Compounds > almotriptan
Page last updated: 2024-09-03

almotriptan and vardenafil

almotriptan has been researched along with vardenafil in 4 studies

Compound Research Comparison

Studies
(almotriptan)		Trials
(almotriptan)		Recent Studies (post-2010)
(almotriptan)		Studies
(vardenafil)		Trials
(vardenafil)		Recent Studies (post-2010) (vardenafil)
188594232020

Protein Interaction Comparison

ProteinTaxonomyalmotriptan (IC50)vardenafil (IC50)
cystic fibrosis transmembrane conductance regulatorHomo sapiens (human)0.14
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)1.7801
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit deltaHomo sapiens (human)0.0077
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)1.6334
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.817
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)0.57
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alphaHomo sapiens (human)0.0077
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammaHomo sapiens (human)0.0077
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)4.15
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit betaHomo sapiens (human)0.0077
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'Homo sapiens (human)0.0077
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1AHomo sapiens (human)0.265
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)1.3846
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)2.091
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)4.15
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)2.091
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)1.5801
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7AHomo sapiens (human)1.9
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammaHomo sapiens (human)0.0077
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)0.265
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)1.34
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AHomo sapiens (human)1.3701
cAMP-specific 3',5'-cyclic phosphodiesterase 7BHomo sapiens (human)1.6601
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10AHomo sapiens (human)1.4883

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for almotriptan and vardenafil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

3 other study(ies) available for almotriptan and vardenafil

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009