Page last updated: 2024-09-03

almotriptan and trimethoprim

almotriptan has been researched along with trimethoprim in 5 studies

Compound Research Comparison

Studies
(almotriptan)
Trials
(almotriptan)
Recent Studies (post-2010)
(almotriptan)
Studies
(trimethoprim)
Trials
(trimethoprim)
Recent Studies (post-2010) (trimethoprim)
18859426,989845894

Protein Interaction Comparison

ProteinTaxonomyalmotriptan (IC50)trimethoprim (IC50)
Chain A, Dihydrofolate reductaseBacillus anthracis77200
Chain A, dihydrofolate reductase (DHFR)Bacillus anthracis77200
Dihydrofolate reductase Mycobacterium avium0.2588
Dihydrofolate reductaseHomo sapiens (human)1.8206
Dihydrofolate reductaseLacticaseibacillus casei0.3493
Dihydrofolate reductase type 1Escherichia coli0.25
Dihydrofolate reductaseNeisseria gonorrhoeae0.45
Thymidylate synthaseHomo sapiens (human)3.405
Dihydrofolate reductaseStaphylococcus aureus0.0875
Thymidylate synthaseEscherichia coli K-123.405
Dihydrofolate reductaseEscherichia coli K-120.6064
Bifunctional dihydrofolate reductase-thymidylate synthasePlasmodium falciparum K10.01
Dihydrofolate reductase type 1 from Tn4003Staphylococcus aureus0.023
Dipeptidyl peptidase 4Rattus norvegicus (Norway rat)2.7
Dihydrofolate reductasePneumocystis carinii0.7061
Dihydrofolate reductaseCandida albicans0.1361
Dipeptidyl peptidase 4Homo sapiens (human)2.7
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.45
Metabotropic glutamate receptor 5Rattus norvegicus (Norway rat)2.73
Mu-type opioid receptorCavia porcellus (domestic guinea pig)2.8
Bifunctional dihydrofolate reductase-thymidylate synthaseToxoplasma gondii3.2206
Bifunctional dihydrofolate reductase-thymidylate synthasePlasmodium berghei ANKA0.12
Dihydrofolate reductaseStreptococcus pneumoniae TIGR40.0297
Dihydrofolate reductaseLactococcus lactis subsp. lactis Il14030.45
Dihydrofolate reductase Bacillus anthracis4.77
Dihydrofolate reductaseRattus norvegicus (Norway rat)1.244
Dihydrofolate reductase Pneumocystis jirovecii0.092

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for almotriptan and trimethoprim

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

4 other study(ies) available for almotriptan and trimethoprim

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011