almotriptan has been researched along with sumatriptan in 40 studies
| Studies (almotriptan) | Trials (almotriptan) | Recent Studies (post-2010) (almotriptan) | Studies (sumatriptan) | Trials (sumatriptan) | Recent Studies (post-2010) (sumatriptan) |
|---|---|---|---|---|---|
| 188 | 59 | 42 | 2,405 | 461 | 480 |
| Protein | Taxonomy | almotriptan (IC50) | sumatriptan (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 3E | Homo sapiens (human) | 0.0073 | |
| 5-hydroxytryptamine receptor 3B | Homo sapiens (human) | 0.0073 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.4497 | |
| Carboxypeptidase M | Homo sapiens (human) | 0.02 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.64 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.722 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.64 | |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | 0.3091 | |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | 0.0131 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 7.9433 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 3.9753 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.804 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 0.061 | |
| 5-hydroxytryptamine receptor 1E | Homo sapiens (human) | 5.5 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.64 | |
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | 0.0078 | |
| 5-hydroxytryptamine receptor 5A | Homo sapiens (human) | 0.5012 | |
| 5-hydroxytryptamine receptor 1D | Sus scrofa (pig) | 0.02 | |
| 5-hydroxytryptamine receptor 1A | Mus musculus (house mouse) | 0.45 | |
| 5-hydroxytryptamine receptor 3D | Homo sapiens (human) | 0.0073 | |
| 5-hydroxytryptamine receptor 3C | Homo sapiens (human) | 0.0073 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 6.7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 34 (85.00) | 29.6817 |
| 2010's | 6 (15.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Beleta, J; Bou, J; Domènech, T; Fernández-Forner, D; Gras, J; Heredia, A; Palacios, JM; Puig, J | 1 |
| Bou, J; Fernández, AG; Gras, J; Llenas, J; Palacios, JM | 1 |
| Cardelús, I; Gras, J; Llenas, J; Palacios, JM | 1 |
| Brod, MI; Colman, SS; Gomez-Mancilla, B; Jirgens, KJ; Krishnamurthy, A; Rowland, CR | 1 |
| Hashimoto, S; Iwata, M | 1 |
| Gomez-Mancilla, B; Grosz, DE; Jirgens, KJ; Rowland, CR; Spierings, EL; Whaley, FS | 1 |
| Marcus, DA | 1 |
| Gras, J; Llenas, J; Llupià, J; Palacios, JM | 1 |
| Bou, J; Cortijo, J; Gras, J; Llenas, J; Morcillo, EJ; Palacios, JM | 1 |
| Barr, CE; Goldfarb, SD; Rowland, CR; Torigoe, Y; Wang, E; Wang, JT | 1 |
| Adelman, JU; Goldfarb, SD; Kozma, CM; Mannix, LK; Von, S | 1 |
| Freitag, FG | 1 |
| Palmer, JB; Salonen, R | 1 |
| Tfelt-Hansen, P | 1 |
| Cates, C | 1 |
| Cady, R | 1 |
| Barr, CE; Goldfarb, SD; Wang, JT | 1 |
| Dodick, DW | 1 |
| Rapoport, AM; Sheftell, FD; Tepper, SJ | 1 |
| Csiba, L; Ficzere, A | 1 |
| Cabarrocas, X; Dowson, AJ; Laínez, JM; Massiou, H | 2 |
| Pascual, J | 1 |
| Adelman, JU; Lewit, EJ | 1 |
| Jähnichen, S; Pertz, HH; Radtke, OA | 1 |
| Kowa, H; Nakashima, K; Takeshima, T | 1 |
| Muñoz, P; Pascual, J | 1 |
| Beneke, M; Diener, HC; Gebert, I; Gendolla, A | 1 |
| Capuano, A; Di Trapani, G; Evangelista, M; Ferraro, D; Mei, D; Pierguidi, L; Vollono, C | 1 |
| Diener, HC | 1 |
| Busch, V; Jürgens, TP; Leinisch, E; May, A; Schmidt-Wilcke, T; Schuierer, G | 1 |
| Autret-Leca, E; Beau-Salinas, F; Bensouda-Grimaldi, L; Cissoko, H; Jonville-Béra, AP | 1 |
| Fox, AW; Oberhardt, F | 1 |
| Candela, S; Casolla, B; D'Alonzo, L; Lionetto, L; Martelletti, P; Negro, A; Simmaco, M | 1 |
| Evers, S | 1 |
| Han, W; Li, M; Wang, J; Xu, H | 1 |
14 review(s) available for almotriptan and sumatriptan
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Current topics: expectation for new triptans].
Topics: Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2001 |
Establishing a standard of speed for assessing the efficacy of the serotonin(1B/1D) agonists (triptans).
Topics: Analgesics, Non-Narcotic; Carbazoles; Clinical Trials as Topic; Humans; Indoles; Migraine Disorders; Oxazolidinones; Pain Measurement; Patient Satisfaction; Piperidines; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Treatment Outcome; Triazoles; Tryptamines | 2001 |
Almotriptan versus sumatriptan in migraine treatment: direct medical costs of managing adverse chest symptoms.
Topics: Chest Pain; Drug Costs; Electrocardiography; Humans; Indoles; Migraine Disorders; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; United States | 2002 |
Acute treatment of migraine and the role of triptans.
Topics: Acute Disease; Blood Flow Velocity; Carbazoles; Clinical Trials as Topic; Drug Administration Routes; Female; Humans; Indoles; Male; Menstruation; Migraine Disorders; Oxazolidinones; Piperidines; Practice Guidelines as Topic; Pyrrolidines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines; Vasoconstriction; Vasoconstrictor Agents | 2001 |
Almotriptan reduces the incidence of migraine-associated symptoms: a pooled analysis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Clinical Trials, Phase III as Topic; Female; Humans; Male; Middle Aged; Migraine Disorders; Nausea; Photophobia; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines; Vomiting | 2002 |
Mechanisms of action of the 5-HT1B/1D receptor agonists.
Topics: Carbazoles; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2002 |
[Treatment of migraine in patients with hypertension and ischemic heart disease].
Topics: Adjuvants, Pharmaceutic; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Contraindications; Dihydroergotamine; Dopamine Agonists; Ergotamine; Humans; Hypertension; Indoles; Migraine Disorders; Myocardial Ischemia; Oxazolidinones; Retrospective Studies; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents | 2002 |
Almotriptan: pharmacological differences and clinical results.
Topics: Administration, Oral; Humans; Indoles; Migraine Disorders; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2001 |
Comparative aspects of triptans in treating migraine.
Topics: Carbazoles; Cardiovascular Diseases; Humans; Indoles; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Piperidines; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2001 |
[Meta-analysis of triptan treatment in migraine].
Topics: Carbazoles; Evidence-Based Medicine; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Receptor, Serotonin, 5-HT1D; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2004 |
Treatment of perimenstrual migraine with triptans: an update.
Topics: Female; Humans; Migraine Disorders; Premenstrual Syndrome; Randomized Controlled Trials as Topic; Sumatriptan; Treatment Outcome; Tryptamines | 2012 |
The efficacy of triptans in childhood and adolescence migraine.
Topics: Adolescent; Analgesics; Child; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Germany; Humans; Male; Migraine Disorders; Oxazolidinones; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2013 |
Network meta-analysis of migraine disorder treatment by NSAIDs and triptans.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Migraine Disorders; Oxazolidinones; Pyrrolidines; Randomized Controlled Trials as Topic; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2016 |
10 trial(s) available for almotriptan and sumatriptan
| Article | Year |
|---|---|
Treatment satisfaction, functional status, and health-related quality of life of migraine patients treated with almotriptan or sumatriptan.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Indoles; Male; Middle Aged; Migraine Disorders; Patient Satisfaction; Quality of Life; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2001 |
Oral almotriptan vs. oral sumatriptan in the abortive treatment of migraine: a double-blind, randomized, parallel-group, optimum-dose comparison.
Topics: Administration, Oral; Adolescent; Adult; Aged; Cardiovascular System; Chi-Square Distribution; Double-Blind Method; Female; Humans; Indoles; Male; Middle Aged; Migraine with Aura; Migraine without Aura; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2001 |
Almotriptan versus sumatriptan in migraine treatment: direct medical costs of managing adverse chest symptoms.
Topics: Chest Pain; Drug Costs; Electrocardiography; Humans; Indoles; Migraine Disorders; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; United States | 2002 |
Almotriptan increases sustained pain-free outcomes in acute migraine: results from three controlled clinical trials.
Topics: Acute Disease; Adult; Female; Humans; Indoles; Male; Middle Aged; Migraine Disorders; Palliative Care; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 2002 |
Almotriptan is an effective and well-tolerated treatment for migraine pain: results of a randomized, double-blind, placebo-controlled clinical trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Indoles; Male; Middle Aged; Migraine Disorders; Multicenter Studies as Topic; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 2002 |
Almotriptan improves response rates when treatment is within 1 hour of migraine onset.
Topics: Acute Disease; Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Indoles; Male; Middle Aged; Migraine Disorders; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Treatment Outcome; Tryptamines | 2004 |
Almotriptan in migraine patients who respond poorly to oral sumatriptan: a double-blind, randomized trial.
Topics: Adolescent; Adult; Aged; Female; Humans; Indoles; Male; Middle Aged; Migraine Disorders; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 2005 |
Multiple attack study on the available triptans in Italy versus placebo.
Topics: Adult; Female; Humans; Indoles; Italy; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2005 |
Efficacy of almotriptan 12.5 mg in achieving migraine-related composite endpoints: a double-blind, randomized, placebo-controlled study in patients controlled study in patients with previous poor response to sumatriptan 50 mg.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Middle Aged; Migraine Disorders; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2005 |
Oral sumatriptan and almotriptan--delimiting the MAOI effect.
Topics: Administration, Oral; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injections, Subcutaneous; Male; Migraine Disorders; Models, Biological; Monoamine Oxidase; Serotonin 5-HT1 Receptor Agonists; Sumatriptan; Time Factors; Tryptamines | 2012 |
17 other study(ies) available for almotriptan and sumatriptan
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Pharmacological characterization of almotriptan: an indolic 5-HT receptor agonist for the treatment of migraine.
Topics: Animals; Cattle; Colforsin; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; HeLa Cells; Humans; Indoles; Male; Meningeal Arteries; Migraine Disorders; Muscle, Smooth, Vascular; Rabbits; Rats; Rats, Wistar; Saphenous Vein; Serotonin Receptor Agonists; Sumatriptan; Swine; Transfection; Tryptamines; Vasoconstriction; Vasoconstrictor Agents | 2000 |
Functional profile of almotriptan in animal models predictive of antimigraine activity.
Topics: Animals; Arteriovenous Anastomosis; Carotid Arteries; Cats; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electric Stimulation; Female; Guinea Pigs; Hemodynamics; Indoles; Male; Meningeal Arteries; Migraine Disorders; Models, Animal; Muscle, Smooth, Vascular; Regional Blood Flow; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstriction; Vasodilation | 2000 |
Cardiovascular safety profile of almotriptan, a new indolic derivative for the treatment of migraine.
Topics: Animals; Blood Pressure; Cardiovascular System; Cats; Coronary Circulation; Coronary Vessels; Dogs; Electrocardiography; Female; Guinea Pigs; Heart Rate; Indoles; Injections, Subcutaneous; Macaca fascicularis; Male; Migraine Disorders; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Safety; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2000 |
[Migraine headache. Severe attacks: triptans are essential].
Topics: Clinical Trials as Topic; Humans; Indoles; Migraine Disorders; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 2001 |
Safety profile of almotriptan, a new antimigraine agent. Effects on central nervous system, renal function and respiratory dynamics.
Topics: Animals; Behavior, Animal; Central Nervous System; Dogs; Drug Interactions; Guinea Pigs; Indoles; Kidney; Kidney Function Tests; Male; Mice; Migraine Disorders; Rats; Respiratory Mechanics; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2001 |
Vascular effects of the new anti-migraine agent almotriptan on human cranial and peripheral arteries.
Topics: Arteries; Basilar Artery; Carotid Artery, Internal; Coronary Vessels; Humans; In Vitro Techniques; Indoles; Meningeal Arteries; Migraine Disorders; Ophthalmic Artery; Pulmonary Veins; Serotonin Receptor Agonists; Sumatriptan; Temporal Arteries; Tryptamines; Vasoconstriction; Vasoconstrictor Agents | 2001 |
Cost savings in migraine associated with less chest pain on new triptan therapy.
Topics: Chest Pain; Cohort Studies; Cost Savings; Cost-Benefit Analysis; Data Collection; Female; Humans; Indoles; Male; Migraine Disorders; Outcome Assessment, Health Care; Retrospective Studies; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; United States | 2002 |
Triptan medications to treat acute migraine.
Topics: Acute Disease; Humans; Indoles; Meta-Analysis as Topic; Migraine Disorders; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2002 |
Triptan medications to treat acute migraine.
Topics: Acute Disease; Clinical Trials as Topic; Humans; Indoles; Meta-Analysis as Topic; Migraine Disorders; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2002 |
Triptan medications to treat acute migraine.
Topics: Acute Disease; Humans; Indoles; Meta-Analysis as Topic; Migraine Disorders; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2002 |
Impact of chest pain on cost of migraine treatment with almotriptan and sumatriptan.
Topics: Adolescent; Adult; Chest Pain; Cohort Studies; Cost Savings; Cost-Benefit Analysis; Drug Costs; Electrocardiography; Female; Health Care Costs; Humans; Male; Middle Aged; Migraine Disorders; Retrospective Studies; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 2002 |
Involvement of 5-HT1B receptors in triptan-induced contractile responses in guinea-pig isolated iliac artery.
Topics: Animals; Benzamides; Brain; Carbazoles; Dinoprost; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endothelium, Vascular; Female; Forecasting; Guinea Pigs; Iliac Artery; Indoles; Ketanserin; Male; Muscle Contraction; Muscle, Smooth; Oxadiazoles; Oxazolidinones; Piperazines; Piperidines; Pyrrolidines; Receptor, Serotonin, 5-HT1B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Sumatriptan; Triazoles; Tryptamines | 2004 |
Correlation between lipophilicity and triptan outcomes.
Topics: Central Nervous System Diseases; Chemical Phenomena; Chemistry, Physical; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Statistics as Topic; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2005 |
Migraine-like headache in intracranial haemorrhage is alleviated by sumatriptan and almotriptan.
Topics: Adult; Diagnosis, Differential; Drug Therapy, Combination; Headache; Humans; Intracranial Hemorrhages; Male; Migraine Disorders; Sumatriptan; Tryptamines | 2008 |
Drug dependence associated with triptans and ergot derivatives: a case/non-case study.
Topics: Claviceps; Dihydroergotamine; Ergotamine; Humans; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Risk; Substance-Related Disorders; Sumatriptan; Tryptamines | 2010 |