Compounds > almotriptan
Page last updated: 2024-09-03

almotriptan and itraconazole

almotriptan has been researched along with itraconazole in 4 studies

Compound Research Comparison

Studies
(almotriptan)		Trials
(almotriptan)		Recent Studies (post-2010)
(almotriptan)		Studies
(itraconazole)		Trials
(itraconazole)		Recent Studies (post-2010) (itraconazole)
18859422494108

Protein Interaction Comparison

ProteinTaxonomyalmotriptan (IC50)itraconazole (IC50)
Tyrosine-protein kinase FynHomo sapiens (human)3.89
ATP-dependent translocase ABCB1Mus musculus (house mouse)0.7
ATP-dependent translocase ABCB1Homo sapiens (human)1.666
Cytochrome P450 3A4Homo sapiens (human)0.4256
ATP-dependent translocase ABCB1Mus musculus (house mouse)0.2
C-X-C chemokine receptor type 1Homo sapiens (human)2.5676
CruzipainTrypanosoma cruzi3
Vasopressin V2 receptorHomo sapiens (human)3.476
C-C chemokine receptor type 4Homo sapiens (human)3.2689
Lanosterol 14-alpha demethylaseHomo sapiens (human)3.6
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)2

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for almotriptan and itraconazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

3 other study(ies) available for almotriptan and itraconazole

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009