Page last updated: 2024-09-03

almotriptan and diclofenac

almotriptan has been researched along with diclofenac in 6 studies

Compound Research Comparison

Studies (almotriptan)	Trials (almotriptan)	Recent Studies (post-2010) (almotriptan)	Studies (diclofenac)	Trials (diclofenac)	Recent Studies (post-2010) (diclofenac)
188	59	42	8,874	1,874	3,616

Protein Interaction Comparison

Protein	Taxonomy	diclofenac (IC50)
Aldo-keto reductase family 1 member B10	Homo sapiens (human)	1.9
Prostaglandin G/H synthase 1	Bos taurus (cattle)	0.003
Prostaglandin G/H synthase 1	Ovis aries (sheep)	1.3376
Interleukin-8	Homo sapiens (human)	0.008
Prostaglandin G/H synthase 1	Homo sapiens (human)	0.0415
Sodium- and chloride-dependent GABA transporter 1	Rattus norvegicus (Norway rat)	0.5
C-X-C chemokine receptor type 1	Homo sapiens (human)	0.012
Sodium- and chloride-dependent GABA transporter 2	Rattus norvegicus (Norway rat)	0.5
Sodium- and chloride-dependent GABA transporter 3	Rattus norvegicus (Norway rat)	0.5
Prostaglandin G/H synthase 2	Homo sapiens (human)	0.4165
Prostaglandin G/H synthase 2	Rattus norvegicus (Norway rat)	0.5
Sodium- and chloride-dependent betaine transporter	Rattus norvegicus (Norway rat)	0.5
Prostaglandin G/H synthase 2	Ovis aries (sheep)	1.6867
Prostaglandin G/H synthase 2	Mus musculus (house mouse)	0.0502
Solute carrier family 22 member 6	Homo sapiens (human)	4
Prostaglandin G/H synthase 1	Rattus norvegicus (Norway rat)	0.5
P2Y purinoceptor 12	Rattus norvegicus (Norway rat)	0.02

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (66.67)	29.6817
2010's	2 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
De Klippel, N; Giurgea, S; Herroelen, L; Jacquy, J; Louis, P; Monseu, G; Schoenen, J; Vandenheede, M	1
Burstein, R; Jakubowski, M	1

Reviews

1 review(s) available for almotriptan and diclofenac

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for almotriptan and diclofenac

Article	Year
Almotriptan and its combination with aceclofenac for migraine attacks: a study of efficacy and the influence of auto-evaluated brush allodynia. Cephalalgia : an international journal of headache, 2008, Volume: 28, Issue:10 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Middle Aged; Migraine Disorders; Multivariate Analysis; Physical Stimulation; Pilot Projects; Prevalence; Serotonin Receptor Agonists; Somatosensory Disorders; Treatment Outcome; Tryptamines	2008

Article

Year

Almotriptan and its combination with aceclofenac for migraine attacks: a study of efficacy and the influence of auto-evaluated brush allodynia.

Cephalalgia : an international journal of headache, 2008, Volume: 28, Issue:10

Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Middle Aged; Migraine Disorders; Multivariate Analysis; Physical Stimulation; Pilot Projects; Prevalence; Serotonin Receptor Agonists; Somatosensory Disorders; Treatment Outcome; Tryptamines

2008

Other Studies

4 other study(ies) available for almotriptan and diclofenac

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
Almotriptan efficacy in migraine with allodynia: a critique of Schoenen et al. Cephalalgia : an international journal of headache, 2009, Volume: 29, Issue:10 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Middle Aged; Migraine Disorders; Multivariate Analysis; Physical Stimulation; Pilot Projects; Prevalence; Serotonin Receptor Agonists; Somatosensory Disorders; Treatment Outcome; Tryptamines	2009