Compounds > allysine

allysine and 2-aminoadipic acid

allysine has been researched along with 2-aminoadipic acid in 68 studies

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-19907 (10.29)18.7374
1990's7 (10.29)18.2507
2000's14 (20.59)29.6817
2010's34 (50.00)24.3611
2020's6 (8.82)2.80

Authors

AuthorsStudies
Diedrich, DL; Schnaitman, CA1
Bode, R; Hammer, T1
Chang, YF; Ghosh, P; Rao, VV1
Chang, YF; Rao, VV1
Dölz, R; Heidemann, E1
Dubois, E; Piérard, A; Ramos, F1
Eyre, DR; Gallop, PM; Paz, MA1
Crombie, G; Faris, B; Franzblau, C; Snider, R1
Dubois, E; Feller, A; Piérard, A; Ramos, F3
Ehmann, DE; Gehring, AM; Walsh, CT1
Jahanmard, E; Suyama, K1
Akagawa, M; Suyama, K1
Daneshvar, B; Dragsted, LO; Hansen, M; Lauridsen, ST; Sandström, B; Young, JF1
Suyama, K; Takeuchi, M; Umeda, H1
Kawamorita, K; Suyama, K; Umeda, H1
VOGEL, HJ; YURA, T1
ASPEN, AJ; MEISTER, A1
Jiménez-Escrig, A; Orensanz, L; Pulido, R; Saura-Calixto, F1
Akagawa, M; Kurota, Y; Sasaki, D; Suyama, K1
Akagawa, M; Ishii, Y; Kurota, Y; Sasaki, D; Suyama, K; Uchida, K; Yotsu-Yamashita, M1
Hirota, T; Ikeda, T; Miura, S; Murai, T; Oitate, M1
Cha, SS; Cheng, CH; Fong, WP; Lam, YM; Tang, WK; Wong, KB1
Jakobs, C; Jozwiak, S; Kacinski, M; Kaczorowska, M; Kmiec, T; Kroczka, S; Salomons, GS; Struys, EA1
Estévez, M; Heinonen, M; Ollilainen, V1
Gospe, SM; Hahn, SH; Sadilkova, K1
Fan, X; Giblin, FJ; Liu, X; Monnier, VM; Nemet, I; Qian, J; Strauch, C; Theves, M; Zhang, J1
Aylett, S; Baxter, P; Christensen, E; Clayton, PT; Craigen, WJ; De Lonlay, P; Dulac, O; Feillet, F; Footitt, EJ; Hemingway, C; Hughes, MI; Jakobs, C; Marlow, N; Mills, KA; Mills, PB; Nabbout, R; Pike, MG; Rennie, J; Schmitt, B; Struys, EA; Tuschl, K; Varadkar, S; Zuberi, SM1
Hoffmann, GF; Koeller, DM; Kölker, S; Okun, JG; Opp, S; Sauer, SW1
Bisson, WH; Chavez, JD; Maier, CS1
Chan, CL; Chan, MK; Fong, WP; Wong, CP; Wong, JW1
Brocker, C; Cantore, M; Failli, P; Vasiliou, V1
Afiuni-Zadeh, S; Azimi, G; Guo, X; Lankmayr, E1
Bok, LA; Emal, D; Houterman, S; Jakobs, C; Struys, EA; Willemsen, MA1
Ceyhan, S; Clayton, PT; Footitt, EJ; Jakobs, C; Mills, PB; Struys, EA; Waters, PJ1
Connolly, MB; Coulter-Mackie, M; Horvath, GA; Jakobs, C; Mercimek-Mahmutoglu, S; Nelson, T; Sargent, M; Stockler-Ipsiroglu, S; Struys, E; Waters, PJ1
De Smet, S; Estévez, M; Morcuende, D; Utrera, M; Vossen, E1
Alfadhel, M; Coulter-Mackie, M; Sirrs, S; Stockler-Ipsiroglu, S; Struys, E; Szeitz, A; Waters, PJ1
Armenteros, M; Estévez, M; Solano, F; Utrera, M; Ventanas, S1
Bok, LA; Cheng, B; Collet, JP; Connolly, M; Coughlin, CR; Das, AM; Gospe, SM; Hartmann, H; Jaggumantri, S; Jakobs, C; Mercimek-Mahmutoglu, S; Meyer, U; Plecko, BR; Sinclair, G; Stockler, S; Struys, E; van der Lee, JH; Van Hove, J; van Karnebeek, CD1
Al-Saman, AS; Rizk, TM1
Al Shahwan, S; Bakkali, A; Nota, B; Salomons, GS; Struys, EA; Tabarki, B1
Estévez, M; Villaverde, A1
Gospe, SM; Hahn, SH; Jung, S; Tran, NT1
Ferrer-López, I; Merinero, B; Pérez-Cerdá, C; Ruiz-Sala, P; Ugarte, M1
Estévez, M; Morcuende, D; Utrera, M1
Davidson, VL; Sanchez-Amat, A; Sehanobish, E; Shin, S1
Qin, J; Yang, ZX1
Frolov, A; Greifenhagen, U; Hoffmann, R1
Arruda, P; Eberlin, MN; Laranjeira, ÂB; MacKenzie, A; Marques, LA; Pena, IA; Yunes, JA1
Al Teneiji, A; Bruun, TU; Cordeiro, D; Inbar-Feigenberg, M; Mercimek-Mahmutoglu, S; Patel, J; Struys, E; Weiss, S1
Dai, S; Fang, X; Hsu, WW; Kurra, Y; Liu, WR; Tharp, JM; Vatansever, EC; Wang, X; Wang, ZA; Zeng, Y1
Caravan, P; Chen, HH; Ferreira, DS; Jones, CM; Koerner, SK; Probst, CK; Rotile, NJ; Tager, AM; Waghorn, PA1
Caravan, P; Jones, CM; Oliveira, BL; Tager, AM; Waghorn, PA1
Estévez, M; Luna, C1
Crowther, LM; Mathis, D; Plecko, B; Poms, M1
Evans, CR; Jones, AE; Karnovsky, A; Michailidis, G; Puskarich, MA; Stringer, KA1
Abston, E; Caravan, P; Désogère, P; Fuchs, BC; Graham-O'Regan, KA; Lanuti, M; Rotile, NJ; Santos Ferreira, DD; Schirmer, MD; Sui, J; Wahsner, J; Wang, J1
Bank, RA; Piersma, B1
Carrapiso, A; Carvalho, L; Delgado, J; Estévez, M; Martín, L; Padilla, P1
Gong, P; Jiang, S; Jiang, Y; Li, H; Wang, J; Wu, M; Wu, Y; Xue, J; Yang, W; Yang, Z; Yuzyuk, T; Zhang, Y1
Hedtke, T; Heinz, A; Schmelzer, CEH1
Chen, H; DeVita, RJ; Dodatko, T; Houten, SM; Leandro, J; Stauffer, B; Yu, C1
Bouchereau, J; Schiff, M1
Ahmed, F; Husain, M; Kleffmann, T1
An, N; Li, X; Shen, X; Sun, X; Wang, J; Yuan, Q; Zhang, Y; Zhao, Y1
Akam, EA; Ay, I; Boice, AT; Caravan, P; Chen, YI; Drummond, M; Gonzalez-Villalobos, RA; Hansen, MK; Hariri, LP; Knipe, RS; Ma, H; Moon, BF; Pantazopoulos, P; Rotile, NJ; Sojoodi, M; Tanabe, KK; Wang, H; Weigand-Whittier, J; Zhang, C; Zhou, IY; Zygmont, SE1

Reviews

5 review(s) available for allysine and 2-aminoadipic acid

ArticleYear
Cross-linking in collagen and elastin.
    Annual review of biochemistry, 1984, Volume: 53

    Topics: 2-Aminoadipic Acid; Animals; Basement Membrane; Cells, Cultured; Chemical Phenomena; Chemistry; Collagen; Connective Tissue Diseases; Cross-Linking Reagents; Elastin; Histidine; Humans; Metabolism, Inborn Errors; Models, Molecular; Protein-Lysine 6-Oxidase; Pyridines; Rats

1984
[Advances in clinical and molecular genetic research on pyridoxine dependent epilepsy].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2013, Volume: 51, Issue:11

    Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Anticonvulsants; Biomarkers; Brain; DNA Mutational Analysis; Electroencephalography; Epilepsy; Genetic Association Studies; Humans; Infant; Infant, Newborn; Magnetic Resonance Imaging; Mutation, Missense; Prognosis; Pyridoxine; Seizures; Status Epilepticus

2013
Collagen cross-linking mediated by lysyl hydroxylase 2: an enzymatic battlefield to combat fibrosis.
    Essays in biochemistry, 2019, 09-13, Volume: 63, Issue:3

    Topics: 2-Aminoadipic Acid; Animals; Collagen; Enzyme Inhibitors; Fibrosis; Humans; Hydroxylation; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase; Protein-Lysine 6-Oxidase; Tacrolimus Binding Proteins

2019
Unique molecular networks: Formation and role of elastin cross-links.
    IUBMB life, 2020, Volume: 72, Issue:5

    Topics: 2-Aminoadipic Acid; Aging; Animals; Blood Vessels; Connective Tissue Diseases; Elastic Tissue; Elastin; Humans; Ligaments; Lung; Lysine; Microfibrils; Oxidation-Reduction; Protein Processing, Post-Translational; Protein-Lysine 6-Oxidase; Skin

2020
Inherited Disorders of Lysine Metabolism: A Review.
    The Journal of nutrition, 2020, 10-01, Volume: 150, Issue:Suppl 1

    Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Amino Acid Metabolism, Inborn Errors; Arginine; Brain; Brain Diseases, Metabolic; Brain Diseases, Metabolic, Inborn; Carnitine; Epilepsy; Glutarates; Glutaryl-CoA Dehydrogenase; Humans; Lysine; Metabolic Diseases; Pyridoxal Phosphate; Pyridoxine

2020

Trials

2 trial(s) available for allysine and 2-aminoadipic acid

ArticleYear
The effect of grape-skin extract on oxidative status.
    The British journal of nutrition, 2000, Volume: 84, Issue:4

    Topics: 2-Aminoadipic Acid; Adult; Analysis of Variance; Antioxidants; Ascorbic Acid; Biomarkers; Catalase; Cross-Over Studies; Erythrocytes; Female; Flavonoids; Glutathione Peroxidase; Glutathione Reductase; Humans; Lipoproteins, LDL; Male; Malondialdehyde; Oxidation-Reduction; Rosales; Superoxide Dismutase

2000
Untargeted Metabolomics Differentiates l-Carnitine Treated Septic Shock 1-Year Survivors and Nonsurvivors.
    Journal of proteome research, 2019, 05-03, Volume: 18, Issue:5

    Topics: 2-Aminoadipic Acid; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Carnitine; Chromatography, Liquid; Fibrinopeptide A; Histamine; Humans; Male; Metabolome; Middle Aged; Prognosis; Severity of Illness Index; Shock, Septic; Survival Analysis; Survivors; Tandem Mass Spectrometry

2019

Other Studies

61 other study(ies) available for allysine and 2-aminoadipic acid

ArticleYear
Lysyl-derived aldehydes in outer membrane proteins of Escherichia coli.
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:8

    Topics: 2-Aminoadipic Acid; Aldehydes; Amino Acids, Dicarboxylic; Chromatography, Thin Layer; Escherichia coli; Mass Spectrometry; Membrane Proteins

1978
Enzymatic production of alpha-aminoadipate-delta-semialdehyde and related compounds by lysine epsilon-dehydrogenase from Candida albicans.
    Zentralblatt fur Mikrobiologie, 1992, Volume: 147, Issue:1-2

    Topics: 2-Aminoadipic Acid; Amino Acid Oxidoreductases; Candida albicans; Culture Media; Hydrogen-Ion Concentration; Lysine; Temperature

1992
L-pipecolic acid metabolism in human liver: L-alpha-aminoadipate delta-semialdehyde oxidoreductase.
    Biochimica et biophysica acta, 1990, May-08, Volume: 1038, Issue:3

    Topics: 2-Aminoadipic Acid; Adult; Aldehyde Oxidoreductases; Coenzymes; Humans; Hydrogen-Ion Concentration; Kinetics; L-Aminoadipate-Semialdehyde Dehydrogenase; Liver; Microbodies; Pipecolic Acids; Povidone; Pseudomonas; Silicon Dioxide; Substrate Specificity

1990
L-pipecolic acid metabolism in human liver: detection of L-pipecolate oxidase and identification of its reaction product.
    Biochimica et biophysica acta, 1990, May-08, Volume: 1038, Issue:3

    Topics: 2-Aminoadipic Acid; Adult; Amino Acids; Biomarkers; Chromatography, Thin Layer; Humans; Liver; Microbodies; Oxidoreductases Acting on CH-NH Group Donors; Pipecolic Acids

1990
Reactivity of the allysine aldehyde group.
    Connective tissue research, 1989, Volume: 18, Issue:4

    Topics: 2-Aminoadipic Acid; Aldehydes; Amines; Amino Acids, Dicarboxylic; Benzyl Compounds; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Imidazoles; Magnetic Resonance Spectroscopy; Mass Spectrometry; Phthalic Acids; Propylamines; Solvents

1989
Control of enzyme synthesis in the lysine biosynthetic pathway of Saccharomyces cerevisiae. Evidence for a regulatory role of gene LYS14.
    European journal of biochemistry, 1988, Jan-15, Volume: 171, Issue:1-2

    Topics: 2-Aminoadipic Acid; Amino Acids, Dicarboxylic; Cloning, Molecular; Enzyme Induction; Enzyme Repression; Gene Expression Regulation; Genes, Fungal; Genes, Regulator; Lysine; Saccharomyces cerevisiae; Saccharopine Dehydrogenases; Transcription, Genetic

1988
Lysine-derived cross-links in the egg shell membrane.
    Biochimica et biophysica acta, 1981, Jan-08, Volume: 640, Issue:1

    Topics: 2-Aminoadipic Acid; Amino Acids; Amino Acids, Dicarboxylic; Animals; Borohydrides; Desmosine; Egg Shell; Lysine; Membrane Proteins

1981
Repression of the genes for lysine biosynthesis in Saccharomyces cerevisiae is caused by limitation of Lys14-dependent transcriptional activation.
    Molecular and cellular biology, 1994, Volume: 14, Issue:10

    Topics: 2-Aminoadipic Acid; Amino Acid Sequence; Amino Acids; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA-Binding Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, Reporter; Lysine; Molecular Sequence Data; Mutagenesis; Recombinant Fusion Proteins; Restriction Mapping; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serine Endopeptidases; Trans-Activators; Transcription, Genetic

1994
Lys80p of Saccharomyces cerevisiae, previously proposed as a specific repressor of LYS genes, is a pleiotropic regulatory factor identical to Mks1p.
    Yeast (Chichester, England), 1997, Volume: 13, Issue:14

    Topics: 2-Aminoadipic Acid; Citric Acid Cycle; Cloning, Molecular; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, Suppressor; Ketoglutaric Acids; Lysine; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors

1997
In Saccharomyces cerevisae, feedback inhibition of homocitrate synthase isoenzymes by lysine modulates the activation of LYS gene expression by Lys14p.
    European journal of biochemistry, 1999, Volume: 261, Issue:1

    Topics: 2-Aminoadipic Acid; Base Sequence; Cloning, Molecular; DNA Primers; DNA-Binding Proteins; Feedback; Fungal Proteins; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Genes, Fungal; Isoenzymes; Kinetics; Lysine; Mutation; Oxo-Acid-Lyases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Subcellular Fractions; Trans-Activators

1999
Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha-aminoadipate reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5.
    Biochemistry, 1999, May-11, Volume: 38, Issue:19

    Topics: 2-Aminoadipic Acid; Acyl Carrier Protein; Aldehyde Oxidoreductases; Carbocysteine; Escherichia coli; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; NADP; Protein Processing, Post-Translational; Saccharomyces cerevisiae; Sulfur Radioisotopes

1999
Bisphenol derivative of allysine for high-performance liquid chromatographic analysis of allysine residue of proteins.
    Journal of chromatography. B, Biomedical sciences and applications, 2000, Mar-10, Volume: 739, Issue:2

    Topics: 2-Aminoadipic Acid; Animals; Cattle; Chromatography, High Pressure Liquid; Phenols; Reproducibility of Results; Spectrophotometry, Ultraviolet

2000
Mechanism of formation of elastin crosslinks.
    Connective tissue research, 2000, Volume: 41, Issue:2

    Topics: 2-Aminoadipic Acid; Aldehydes; Amino Acids; Butylamines; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cross-Linking Reagents; Desmosine; Elastin; Hydrogen-Ion Concentration; Isodesmosine; Lysine; Pyridinium Compounds

2000
Two new elastin cross-links having pyridine skeleton. Implication of ammonia in elastin cross-linking in vivo.
    The Journal of biological chemistry, 2001, Apr-20, Volume: 276, Issue:16

    Topics: 2-Aminoadipic Acid; Aging; Amino Acids; Ammonium Chloride; Animals; Aorta; Carbon Tetrachloride Poisoning; Cattle; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Elastin; Humans; Liver; Liver Cirrhosis, Experimental; Lung; Male; Nuclear Magnetic Resonance, Biomolecular; Pyridines; Rats; Rats, Wistar; Reference Values

2001
High-performance liquid chromatographic quantification of allysine as bis-p-cresol derivative in elastin.
    Amino acids, 2001, Volume: 20, Issue:2

    Topics: 2-Aminoadipic Acid; Age Factors; Animals; Aorta; Cattle; Chromatography, High Pressure Liquid; Cresols; Elastin; Hydrolysis; Magnetic Resonance Spectroscopy; Rats; Spectrometry, Mass, Fast Atom Bombardment

2001
On the glutamic family and lysine in Neurospora; enzymic formation of glutamic gamma-semialdehyde and alpha-aminoadipic delta-semialdehyde from penta-and hexahomoserine.
    Biochimica et biophysica acta, 1957, Volume: 24, Issue:3

    Topics: 2-Aminoadipic Acid; Amino Acids; Glutamates; Lysine; Neurospora; Oligosaccharides; Oxidoreductases; Rubiaceae

1957
The preparation and some properties of alpha-aminoadipic-delta-semialdehyde (delta1-piperideine-6-carboxylic acid).
    Biochemistry, 1962, Volume: 1

    Topics: 2-Aminoadipic Acid; Carboxylic Acids; Pyridines

1962
Study of plasma antioxidant status in Alzheimer's disease.
    European journal of neurology, 2005, Volume: 12, Issue:7

    Topics: 2-Aminoadipic Acid; Alzheimer Disease; Antioxidants; Apolipoproteins E; Biomarkers; Fluorescence Recovery After Photobleaching; Free Radical Scavengers; Genotype; Humans; Oxidation-Reduction; Polymerase Chain Reaction; Polymorphism, Genetic; Uric Acid

2005
Formation of alpha-aminoadipic and gamma-glutamic semialdehydes in proteins by the maillard reaction.
    Annals of the New York Academy of Sciences, 2005, Volume: 1043

    Topics: 2-Aminoadipic Acid; Amidines; Carcinogens; Glutamates; Glycation End Products, Advanced; Humans; Maillard Reaction; Mutagens; Proteins; Serum Albumin; Serum Albumin, Bovine

2005
New method for the quantitative determination of major protein carbonyls, alpha-aminoadipic and gamma-glutamic semialdehydes: investigation of the formation mechanism and chemical nature in vitro and in vivo.
    Chemical research in toxicology, 2006, Volume: 19, Issue:8

    Topics: 2-Aminoadipic Acid; Animals; Ascorbic Acid; Blood Proteins; Cattle; Chromatography, High Pressure Liquid; Glutamates; Humans; Hydrogen Peroxide; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Oxidation-Reduction; Protein Carbonylation; Rats; Transferrin

2006
Covalent binding of rofecoxib, but not other cyclooxygenase-2 inhibitors, to allysine aldehyde in elastin of human aorta.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:10

    Topics: 2-Aminoadipic Acid; Aged; Aldehydes; Animals; Aorta, Abdominal; Aorta, Thoracic; Cell Line; Cyclooxygenase 2 Inhibitors; Elastin; Female; Humans; Lactones; Male; Rats; Rats, Sprague-Dawley; Sulfones

2007
The crystal structure of seabream antiquitin reveals the structural basis of its substrate specificity.
    FEBS letters, 2008, Sep-03, Volume: 582, Issue:20

    Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Animals; Crystallography, X-Ray; Epilepsy; Fish Proteins; Humans; Mutation; NAD; Protein Conformation; Pyridoxine; Sea Bream; Substrate Specificity

2008
Pyridoxine-dependent seizures caused by alpha amino adipic semialdehyde dehydrogenase deficiency: the first polish case with confirmed biochemical and molecular pathology.
    Journal of child neurology, 2008, Volume: 23, Issue:12

    Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Female; Humans; Poland; Pyridoxine; Seizures; Vitamin B Complex

2008
Analysis of protein oxidation markers alpha-aminoadipic and gamma-glutamic semialdehydes in food proteins using liquid chromatography (LC)-electrospray ionization (ESI)-multistage tandem mass spectrometry (MS).
    Journal of agricultural and food chemistry, 2009, May-13, Volume: 57, Issue:9

    Topics: 2-Aminoadipic Acid; Chromatography, Liquid; Dairy Products; Dietary Proteins; Glutamates; Lactalbumin; Meat; Oxidation-Reduction; Serum Albumin, Bovine; Soybean Proteins; Spectrometry, Mass, Electrospray Ionization

2009
Simultaneous determination of alpha-aminoadipic semialdehyde, piperideine-6-carboxylate and pipecolic acid by LC-MS/MS for pyridoxine-dependent seizures and folinic acid-responsive seizures.
    Journal of neuroscience methods, 2009, Oct-30, Volume: 184, Issue:1

    Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Animals; Calibration; Cattle; Child; Child, Preschool; Chromatography, Liquid; Humans; Leucovorin; Mass Spectrometry; Picolinic Acids; Pipecolic Acids; Protein Stability; Seizures; Temperature; Time Factors

2009
Mechanism of lysine oxidation in human lens crystallins during aging and in diabetes.
    The Journal of biological chemistry, 2009, Dec-11, Volume: 284, Issue:50

    Topics: 2-Aminoadipic Acid; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Cattle; Child; Crystallins; Diabetes Mellitus; Humans; Hydrogen Peroxide; Hyperbaric Oxygenation; Lens, Crystalline; Leucine; Lysine; Metals; Mice; Mice, Inbred C57BL; Middle Aged; Molecular Structure; Oxidants; Oxidation-Reduction; Rabbits; Regression Analysis; Young Adult

2009
Genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy (ALDH7A1 deficiency).
    Brain : a journal of neurology, 2010, Volume: 133, Issue:Pt 7

    Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Biomarkers; Epilepsy; Female; Genotype; Humans; Infant; Male; Mutation, Missense; Phenotype; Pyridoxine

2010
Therapeutic modulation of cerebral L-lysine metabolism in a mouse model for glutaric aciduria type I.
    Brain : a journal of neurology, 2011, Volume: 134, Issue:Pt 1

    Topics: 2-Aminoadipate Transaminase; 2-Aminoadipic Acid; Amino Acid Metabolism, Inborn Errors; Analysis of Variance; Animals; Arginine; Brain; Brain Diseases, Metabolic; Carnitine; Catalase; Glutaryl-CoA Dehydrogenase; Ketoglutaric Acids; Lysine; Mice

2011
A targeted mass spectrometry-based approach for the identification and characterization of proteins containing α-aminoadipic and γ-glutamic semialdehyde residues.
    Analytical and bioanalytical chemistry, 2010, Volume: 398, Issue:7-8

    Topics: 2-Aminoadipic Acid; Animals; Chromatography, Liquid; Glutamates; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Male; Mitochondrial Proteins; Models, Molecular; Oxidation-Reduction; Rats; Rats, Inbred F344; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2010
Human antiquitin: structural and functional studies.
    Chemico-biological interactions, 2011, May-30, Volume: 191, Issue:1-3

    Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Biocatalysis; Cell Cycle; Cyclins; Gene Expression Regulation, Enzymologic; Gene Knockdown Techniques; HEK293 Cells; Humans; Mutagenesis, Site-Directed; Oxidation-Reduction; Substrate Specificity

2011
Aldehyde dehydrogenase 7A1 (ALDH7A1) attenuates reactive aldehyde and oxidative stress induced cytotoxicity.
    Chemico-biological interactions, 2011, May-30, Volume: 191, Issue:1-3

    Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Aldehydes; Animals; CHO Cells; Cricetinae; Cricetulus; Cytosol; Enzyme Activation; Humans; Hydrogen Peroxide; Lipid Peroxidation; Mercaptoethanol; Mitochondria; Oxidants; Oxidative Stress; Recombinant Proteins

2011
Optimization and application of microwave-assisted acid hydrolysis for rapid quantification of protein oxidation markers using LC-MS.
    Talanta, 2011, Sep-30, Volume: 85, Issue:4

    Topics: 2-Aminoadipic Acid; 4-Aminobenzoic Acid; Animals; Biomarkers; Cattle; Chromatography, Liquid; Glutamates; Hydrolysis; Mass Spectrometry; Microwaves; Oxidation-Reduction; Proteins; Time Factors

2011
The measurement of urinary Δ¹-piperideine-6-carboxylate, the alter ego of α-aminoadipic semialdehyde, in Antiquitin deficiency.
    Journal of inherited metabolic disease, 2012, Volume: 35, Issue:5

    Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Diet; Epilepsy; Humans; Lysine; Picolinic Acids

2012
Urinary AASA excretion is elevated in patients with molybdenum cofactor deficiency and isolated sulphite oxidase deficiency.
    Journal of inherited metabolic disease, 2012, Volume: 35, Issue:6

    Topics: 2-Aminoadipic Acid; Adolescent; Amino Acid Metabolism, Inborn Errors; Child; Coenzymes; Cysteine; Humans; Infant, Newborn; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Metabolic Networks and Pathways; Metal Metabolism, Inborn Errors; Metalloproteins; Models, Biological; Molybdenum Cofactors; Molybdoferredoxin; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Sulfite Oxidase; Sulfites

2012
Profound neonatal hypoglycemia and lactic acidosis caused by pyridoxine-dependent epilepsy.
    Pediatrics, 2012, Volume: 129, Issue:5

    Topics: 2-Aminoadipic Acid; Acidosis, Lactic; Aldehyde Dehydrogenase; Alleles; Anticonvulsants; Brain; Diffusion Magnetic Resonance Imaging; DNA Mutational Analysis; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Genetic Carrier Screening; Humans; Hypoglycemia; Infant; Infant, Newborn; Infusions, Intravenous; Magnetic Resonance Imaging; Mutation, Missense; Pyridoxine; Temporal Lobe; Thalamus

2012
Dog rose (Rosa canina L.) as a functional ingredient in porcine frankfurters without added sodium ascorbate and sodium nitrite.
    Meat science, 2012, Volume: 92, Issue:4

    Topics: 2-Aminoadipic Acid; Aldehydes; Animals; Antioxidants; Belgium; Food Preservatives; Food Storage; Fruit; Glutamates; Lipid Peroxidation; Meat Products; Mechanical Phenomena; Pigmentation; Plant Extracts; Proteolysis; Refrigeration; Rosa; Spain; Sus scrofa; Volatile Organic Compounds

2012
Variability of phenotype in two sisters with pyridoxine dependent epilepsy.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2012, Volume: 39, Issue:4

    Topics: 2-Aminoadipic Acid; Disease Progression; Epilepsy; Female; Humans; Phenotype; Siblings; Young Adult

2012
Pre-freezing raw hams affects quality traits in cooked hams: potential influence of protein oxidation.
    Meat science, 2012, Volume: 92, Issue:4

    Topics: 2-Aminoadipic Acid; Animals; Animals, Inbred Strains; Chemical Phenomena; Cold Temperature; Fast Foods; Food Preservation; Food Quality; Glutamates; Humans; Lipid Peroxidation; Lower Extremity; Meat; Mechanical Phenomena; Muscle Proteins; Muscle, Skeletal; Oxidation-Reduction; Protein Carbonylation; Sensation; Spain; Sus scrofa; Upper Extremity

2012
Lysine restricted diet for pyridoxine-dependent epilepsy: first evidence and future trials.
    Molecular genetics and metabolism, 2012, Volume: 107, Issue:3

    Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Child; Child, Preschool; Cognition; Diet; Epilepsy; Female; Humans; Infant; Longitudinal Studies; Lysine; Male; Pipecolic Acids; Pyridoxine

2012
A case of extreme prematurity and delayed diagnosis of pyridoxine-dependent epilepsy.
    Neurosciences (Riyadh, Saudi Arabia), 2012, Volume: 17, Issue:4

    Topics: 2-Aminoadipic Acid; Electroencephalography; Epilepsy; Humans; Infant; Magnetic Resonance Imaging; Male; Premature Birth; Pyridoxine; Vitamin B Complex

2012
Pyridoxine-dependent epilepsy with elevated urinary α-amino adipic semialdehyde in molybdenum cofactor deficiency.
    Pediatrics, 2012, Volume: 130, Issue:6

    Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Brain; Child, Preschool; Consanguinity; Developmental Disabilities; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; DNA Mutational Analysis; Electroencephalography; Epilepsy; Exons; Female; Genetic Carrier Screening; Homozygote; Humans; Infant; Infant, Newborn; Leucovorin; Male; Metal Metabolism, Inborn Errors; Molybdoferredoxin; Neurologic Examination; Pyridoxal Phosphate; Pyridoxine; Sequence Analysis, DNA; Sulfurtransferases

2012
Carbonylation of myofibrillar proteins through the maillard pathway: effect of reducing sugars and reaction temperature.
    Journal of agricultural and food chemistry, 2013, Mar-27, Volume: 61, Issue:12

    Topics: 2-Aminoadipic Acid; Animals; Carbohydrates; Copper Sulfate; Glutamates; Maillard Reaction; Meat; Muscle Proteins; Myofibrils; Protein Carbonylation; Swine; Temperature

2013
Preliminary investigation of the use of newborn dried blood spots for screening pyridoxine-dependent epilepsy by LC-MS/MS.
    Molecular genetics and metabolism, 2013, Volume: 110, Issue:3

    Topics: 2-Aminoadipic Acid; Biomarkers; Chromatography, Liquid; Epilepsy; Female; Humans; Infant, Newborn; Male; Neonatal Screening; Retrospective Studies; Tandem Mass Spectrometry

2013
Determination of urinary alpha-aminoadipic semialdehyde by LC-MS/MS in patients with congenital metabolic diseases.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014, Jan-01, Volume: 944

    Topics: 2-Aminoadipic Acid; Adolescent; Child, Preschool; Chromatography, Liquid; Epilepsy; Humans; Infant; Infant, Newborn; Linear Models; Metal Metabolism, Inborn Errors; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2014
Temperature of frozen storage affects the nature and consequences of protein oxidation in beef patties.
    Meat science, 2014, Volume: 96, Issue:3

    Topics: 2-Aminoadipic Acid; Aldehydes; Animals; Cattle; Color; Cooking; Dietary Proteins; Fatty Acids; Food Quality; Food Storage; Freezing; Meat; Oxidation-Reduction; Thiobarbituric Acid Reactive Substances

2014
Steady-state kinetic mechanism of LodA, a novel cysteine tryptophylquinone-dependent oxidase.
    FEBS letters, 2014, Mar-03, Volume: 588, Issue:5

    Topics: 2-Aminoadipic Acid; Bacterial Proteins; Coenzymes; Dipeptides; Hydrogen-Ion Concentration; Indolequinones; Kinetics; Lysine; Marinomonas; Models, Chemical; Proteins

2014
Oxidative degradation of N(ε)-fructosylamine-substituted peptides in heated aqueous systems.
    Amino acids, 2015, Volume: 47, Issue:5

    Topics: 2-Aminoadipic Acid; Chromatography, High Pressure Liquid; Ferrous Compounds; Glucose; Glycation End Products, Advanced; Glycosylation; Hot Temperature; Kinetics; Oxidation-Reduction; Peptides; Reactive Oxygen Species; Solutions; Spectrometry, Mass, Electrospray Ionization; Water

2015
Mouse lysine catabolism to aminoadipate occurs primarily through the saccharopine pathway; implications for pyridoxine dependent epilepsy (PDE).
    Biochimica et biophysica acta. Molecular basis of disease, 2017, Volume: 1863, Issue:1

    Topics: 2-Aminoadipic Acid; Animals; Epilepsy; Female; Lysine; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Picolinic Acids; Pyridoxal Phosphate

2017
Phenotype, biochemical features, genotype and treatment outcome of pyridoxine-dependent epilepsy.
    Metabolic brain disease, 2017, Volume: 32, Issue:2

    Topics: 2-Aminoadipic Acid; Adolescent; Aldehyde Dehydrogenase; Arginine; Child; Child, Preschool; Cohort Studies; Epilepsy; Female; Genotype; Humans; Infant; Lysine; Male; Mutation, Missense; Phenotype; Pyridoxine; Retrospective Studies; Seizures; Treatment Outcome; Vitamins

2017
A Genetically Encoded Allysine for the Synthesis of Proteins with Site-Specific Lysine Dimethylation.
    Angewandte Chemie (International ed. in English), 2017, 01-02, Volume: 56, Issue:1

    Topics: 2-Aminoadipic Acid; Escherichia coli; Genetic Code; Histones; Humans; Lysine; Methylation; Models, Molecular; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Tumor Suppressor Protein p53

2017
Molecular Magnetic Resonance Imaging of Lung Fibrogenesis with an Oxyamine-Based Probe.
    Angewandte Chemie (International ed. in English), 2017, 08-07, Volume: 56, Issue:33

    Topics: 2-Aminoadipic Acid; Amines; Animals; Bleomycin; Chelating Agents; Gadolinium; Magnetic Resonance Imaging; Mice; Molecular Conformation; Molecular Probes; Pulmonary Fibrosis

2017
High sensitivity HPLC method for determination of the allysine concentration in tissue by use of a naphthol derivative.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017, Oct-01, Volume: 1064

    Topics: 2-Aminoadipic Acid; Animals; Aorta; Bleomycin; Chromatography, High Pressure Liquid; Hydrolysis; Limit of Detection; Linear Models; Lung; Mice; Mice, Inbred C57BL; Naphthalenesulfonates; Pulmonary Fibrosis; Reproducibility of Results; Swine

2017
Formation of allysine in β-lactoglobulin and myofibrillar proteins by glyoxal and methylglyoxal: Impact on water-holding capacity and in vitro digestibility.
    Food chemistry, 2019, Jan-15, Volume: 271

    Topics: 2-Aminoadipic Acid; Glycation End Products, Advanced; Glyoxal; Lactoglobulins; Pyruvaldehyde; Water

2019
New insights into human lysine degradation pathways with relevance to pyridoxine-dependent epilepsy due to antiquitin deficiency.
    Journal of inherited metabolic disease, 2019, Volume: 42, Issue:4

    Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Epilepsy; Humans; Lysine; Metabolic Networks and Pathways; Pipecolic Acids; Vitamin B 6

2019
    Journal of the American Chemical Society, 2019, 04-10, Volume: 141, Issue:14

    Topics: 2-Aminoadipic Acid; Acetates; Animals; Gallium Radioisotopes; Heterocyclic Compounds, 1-Ring; Indoles; Mice; Positron-Emission Tomography; Pulmonary Fibrosis

2019
Malondialdehyde interferes with the formation and detection of primary carbonyls in oxidized proteins.
    Redox biology, 2019, Volume: 26

    Topics: 2-Aminoadipic Acid; Humans; Hydrazones; Malondialdehyde; Metabolic Networks and Pathways; Molecular Structure; Oxidation-Reduction; Protein Carbonylation; Proteins

2019
Simultaneous quantification of alpha-aminoadipic semialdehyde, piperideine-6-carboxylate, pipecolic acid and alpha-aminoadipic acid in pyridoxine-dependent epilepsy.
    Scientific reports, 2019, 08-06, Volume: 9, Issue:1

    Topics: 2-Aminoadipic Acid; Biomarkers; Child; Child, Preschool; Chromatography, Liquid; Epilepsy; Female; Humans; Infant; Lysine; Male; Mass Screening; Picolinic Acids; Pipecolic Acids; Tandem Mass Spectrometry

2019
Deletion of 2-aminoadipic semialdehyde synthase limits metabolite accumulation in cell and mouse models for glutaric aciduria type 1.
    Journal of inherited metabolic disease, 2020, Volume: 43, Issue:6

    Topics: 2-Aminoadipic Acid; Amino Acid Metabolism, Inborn Errors; Animals; Brain; Brain Diseases, Metabolic; CRISPR-Cas Systems; Disease Models, Animal; Female; Glutarates; Glutaryl-CoA Dehydrogenase; HEK293 Cells; Humans; Liver; Male; Mice; Mice, Knockout

2020
Acetylation, Methylation and Allysine Modification Profile of Viral and Host Proteins during Influenza A Virus Infection.
    Viruses, 2021, 07-20, Volume: 13, Issue:7

    Topics: 2-Aminoadipic Acid; A549 Cells; Acetylation; Animals; Computational Biology; Epithelial Cells; Host-Pathogen Interactions; Humans; Influenza A virus; Influenza, Human; Mass Spectrometry; Methylation; Orthomyxoviridae; Orthomyxoviridae Infections; Protein Processing, Post-Translational; Swine

2021
Efficient biosynthesis of α-aminoadipic acid via lysine catabolism in Escherichia coli.
    Biotechnology and bioengineering, 2023, Volume: 120, Issue:1

    Topics: 2-Aminoadipic Acid; Escherichia coli; Lysine; Saccharomyces cerevisiae; Saccharopine Dehydrogenases

2023
Tailored Chemical Reactivity Probes for Systemic Imaging of Aldehydes in Fibroproliferative Diseases.
    Journal of the American Chemical Society, 2023, 09-27, Volume: 145, Issue:38

    Topics: 2-Aminoadipic Acid; Aldehydes; Animals; Lung; Magnetic Resonance Imaging; Mice

2023