allylsilane has been researched along with 10-hydroxyasimicin* in 1 studies
1 other study(ies) available for allylsilane and 10-hydroxyasimicin
Article | Year |
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Highly stereoselective and modular syntheses of 10-hydroxytrilobacin and three diastereomers via stereodivergent [3 + 2]-annulation reactions.
A convergent synthesis of the annonaceous acetogenin, 10-hydroxytrilobacin ( 4a), was accomplished by using the [3 + 2]-annulation reaction of tetrahydrofuranyl carboxaldehyde 2a and allylsilane 3. The stereodivergency of the [3 + 2]-annulation reaction made it possible to achieve modular, highly stereoselective syntheses of three 10-hydroxytrilobacin diastereomers from the same precursors by using simple modifications of reaction conditions. Topics: Aldehydes; Alkenes; Alkynes; Furans; Silanes; Stereoisomerism | 2008 |