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allylisopropylacetamide and phenobarbital

allylisopropylacetamide has been researched along with phenobarbital in 71 studies

Research

Studies (71)

Timeframe	Studies, this research(%)	All Research%
pre-1990	66 (92.96)	18.7374
1990's	5 (7.04)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bradshaw, JJ; Harrison, GG; Ivanetich, KM; Kaminsky, LS; Marsh, JA; Webber, BL	1
Bradshaw, JJ; Harrison, GG; Ivanetich, KM; Kaminsky, LS; Marsh, JA	1
Correia, MA; Dinizo, SE; Kumbara, H; Mico, BA; Ortiz de Montellano, PR; Yost, GS	1
Farrell, GC; Kunze, KL; Ortiz de Montellano, PR; Schmid, R	1
Mico, BA; Ortiz de Montellano, PR; Yost, GS	1
De Matteis, F; Edwards, PM; Francis, JE	1
de Matteis, F; Unseld, A	1
Correia, MA; Farrell, GC; Mico, BA; Ortiz de Montellano, PR; Schmid, R; Yost, GS	1
Banerjee, S; Conney, AH; Kuntzman, R; Levin, W; Somogyi, A	1
Baird, MB; Birnbaum, LS; Massie, HR; Samis, HB; Zimmerman, JA	1
Smith, A	2
Granick, S; Sinclair, PR	1
Padmanaban, G; Rajamanickam, C; Rao, MR	1
Deitrich, RA; Erwin, G; Troxell, PA	1
Cochón, AC; San Martín de Viale, LC; Wainstok de Calmanovici, R	1
Azri, S; Dale, O; Hagen, B; Neverdal, G; Nilsen, OG	1
Atsmon, A; Mamet, R; Mevasser, R; Schoenfeld, N	1
Atsmon, A; Bomstein, Y; Mamet, R; Mevasser, R; Schoenfeld, N	1
Elliott, WH; Hobbs, AA; Mattschoss, LA; May, BK; Williams, KE	1
Abbott, V; Deloria, LB; Mannering, GJ	1
Robertson, LW; Rodman, LE; Shedlofsky, SI; Swim, AT	1
Bawden, MJ; Elliott, WH; Hansen, AJ; May, BK	1
Hansen, AJ; May, BK	1
Bawden, MJ; Hansen, AJ; May, BK; Srivastava, G	1
Anderson, A; Bawden, MJ; May, BK; Srivastava, G	1
Bhat, GJ; Dwarki, VJ; Francis, VN; Padmanaban, G	1
De Matteis, F; Harvey, C; Martin, SR	1
Premereur, N; Roels, F; Van den Branden, C	1
Liem, HH; Miyai, K; Muller-Eberhard, U; Willson, RA	1
Bock, KW; Fröhling, W; Weiner, R	1
Gayathri, AK; Padmanaban, G	1
Behrens, BC; Bryan, GT; Ichikawa, M; Wang, CY	1
Balchum, OJ; Goldstein, BD	1
Padmanaban, G; Rao, MR	1
Kikuchi, G; Kim, HJ; Oashi, A; Tomita, Y; Watarai, K	1
De Matteis, F	2
Lacroix, S; Rothwell, JD; Sweeney, GD	1
Korinek, J; Moses, HL	1
Rothwell, JD; Sweeney, GD	1
Malathi, K; Padmanaban, G; Rao, MR	1
Badawy, AA; Evans, M	1
Bradshaw, JJ; Ivanetich, KM; Ziman, MR	2
Dunbar, DA; Kaminsky, LS; Murphy, MJ	1
de-Andrade-Silva, E; de-Araujo, PS; Raw, I	1
Schmid, R	1
Bruinvels, J; Pepplinkhuizen, L; Schouten, MJ; Wilson, JH	1
Bonkovsky, HL; Healey, JF; Sinclair, JF; Sinclair, PR; Smith, EL	1
Bar-Nun, S; Oron, L	1
Goodman, AI; Ibraham, NG; Levere, RD; Lutton, JD; Solangi, KB; Svogun, JA	1
Kappas, A; Sassa, S; Schneider, J	1
Breimer, DD; Teunissen, MW; Van Graft, M; Vermeulen, NP	1
Borthwick, IA; Brooker, JD; Elliott, WH; May, BK; Srivastava, G	1
Langry, KC; Ortiz de Montellano, PR; Stearns, RA	1
Light, DR; Loosemore, M; Walsh, C	1
Johnson, EF; Liem, HH; Muller-Eberhard, U	1
Percy, VA; Shanley, BC	1
Ibrahim, NG; Levere, RD; Nelson, JC	1
Muschick, H; Rifkind, AB; Troeger, M	1
Lalwani, ND; Reddy, JK; Reddy, MK; Warren, JR	1
Atsmon, A; Beigel, Y; Epstein, O; Greenblat, Y; Lahav, M; Schoenfeld, N	1
Adzharov, D; Chernev, K; Ivanov, E	1
Gidari, AS; Yeung, TC	1
Loosemore, MJ; Walsh, C; Wogan, GN	1
Dols, DM; Mico, BA; Ortiz de Montellano, PR; Riegelman, S; Silber, B	1
Baird, MB	1
Correia, MA; Farrell, GC	1
Brooker, JD; Elliott, WH; Lim, LK; May, BK; Srivastava, G	1
Golly, I; Hlavica, P	1

Reviews

2 review(s) available for allylisopropylacetamide and phenobarbital

Article	Year
Hepatic heme metabolism: new aspects and speculations. Seminars in liver disease, 1983, Volume: 3, Issue:1 Topics: Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Heme; Liver; Microsomes, Liver; Phenobarbital; Rats	1983
Hepatic and renal effects of peroxisome proliferators: biological implications. Annals of the New York Academy of Sciences, 1982, Volume: 386 Topics: Allylisopropylacetamide; Animals; Carnitine O-Acetyltransferase; Catalase; Clofibrate; Kidney; Lipid Metabolism; Lipofuscin; Liver; Mice; Microbodies; Mitotane; Organoids; Peptides; Phenobarbital; Rats	1982

Other Studies

69 other study(ies) available for allylisopropylacetamide and phenobarbital

Article	Year
An investigation into the hepatic cytochrome P-450 catalysed metabolism of the anaesthetic fluroxene (2,2,2-trifluoroethyl vinyl ether). The South African journal of medical sciences, 1975, Volume: 40, Issue:4 Topics: Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Ether; Ethers; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats	1975
The role of cytochrome P-450 in the toxicity of fluroxene (2,2,2-trifluoroethyl vinyl ether) anaesthesia in vivo. Biochemical pharmacology, 1976, Apr-01, Volume: 25, Issue:7 Topics: Allylisopropylacetamide; Anesthesia; Animals; Benzopyrenes; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethers; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats	1976
Destruction of cytochrome P-450 by 2-isopropyl-4-pentenamide and methyl 2-isopropyl-4-pentenoate: mass spectrometric characterization of prosthetic heme adducts and nonparticipation of epoxide metabolites. Archives of biochemistry and biophysics, 1979, Oct-15, Volume: 197, Issue:2 Topics: Acetamides; Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Epoxy Compounds; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Liver; Mass Spectrometry; Microsomes, Liver; NADP; Phenobarbital; Porphyrins; Rats	1979
Exogenous heme restores in vivo functional capacity of hepatic cytochrome P-450 destroyed by allylisopropylacetamide. Biochemical and biophysical research communications, 1979, Jul-27, Volume: 89, Issue:2 Topics: Acetamides; Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Heme; Kinetics; Male; Microsomes, Liver; Phenobarbital; Rats	1979
Suicidal inactivation of cytochrome P-450. Formation of a heme-substrate covalent adduct. Biochemical and biophysical research communications, 1978, Jul-14, Volume: 83, Issue:1 Topics: Acetamides; Allylisopropylacetamide; Animals; Binding Sites; Cytochrome P-450 Enzyme Inhibitors; Heme; Liver; Phenobarbital; Protein Binding; Rats; Spectrophotometry	1978
The glutathione-linked metabolism of 2-allyl-2-isopropy-lacetamide in rats. Further evidence for the formation of a reactive metabolite. Chemico-biological interactions, 1978, Volume: 23, Issue:2 Topics: Acetamides; Acrylamides; Allylisopropylacetamide; Animals; Bile; Chromatography, Paper; Cytochrome P-450 Enzyme System; Glutathione; Liver; Male; Microsomes, Liver; Phenobarbital; Porphyrins; Rats	1978
Destruction of endogenous and exogenous haem by 2-allyl-2-isopropylacetamide: role of the liver cytochrome P-450 which is inducible by phenobarbitone. The International journal of biochemistry, 1978, Volume: 9, Issue:12 Topics: Acetamides; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; Hexobarbital; Male; Methylcholanthrene; Microsomes, Liver; Paralysis; Phenobarbital; Rats; Sleep; Zoxazolamine	1978
Incorporation of exogenous heme into hepatic cytochrome P-450 in vivo. The Journal of biological chemistry, 1979, Jan-10, Volume: 254, Issue:1 Topics: Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Heme; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Subcellular Fractions	1979
Inhibition of the acute toxicity and adrenocorticolytic effect of 7,12-dimethylbenz(a)anthracene by isopropylvaleramide and allylisopropylacetamide in the rat. Cancer research, 1975, Volume: 35, Issue:9 Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetamides; Adrenal Cortex; Adrenal Glands; Allylisopropylacetamide; Amides; Animals; Barbiturates; Benz(a)Anthracenes; Benzopyrenes; Dimethylnitrosamine; Dose-Response Relationship, Drug; Female; Liver; Methylcholanthrene; Pentobarbital; Phenobarbital; Proadifen; Rats; Secobarbital; Time Factors; Valerates	1975
Allylisopropylacetamide preferentially interacts with the phenobarbital-inducible form of rat hepatic microsomal P-450. Biochemical pharmacology, 1976, Nov-01, Volume: 25, Issue:21 Topics: Acetamides; Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Polychlorinated Biphenyls; Rats	1976
The metabolism of 2-allyl-2-isopropylacetamide in vivo and in the isolated perfused rat liver. Biochemical pharmacology, 1976, Nov-15, Volume: 25, Issue:22 Topics: Acetamides; Allylisopropylacetamide; Animals; Bile Ducts; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Fasting; In Vitro Techniques; Kinetics; Liver; Male; Mathematics; Microsomes, Liver; Models, Biological; Organ Specificity; Perfusion; Phenobarbital; Rats	1976
Heme control on the synthesis of delta-aminolevulinic acid synthetase in cultured chick embryo liver cells. Annals of the New York Academy of Sciences, 1975, Apr-15, Volume: 244 Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Cells, Cultured; Chick Embryo; Deferoxamine; Enzyme Induction; Heme; Hemin; Kinetics; Lead; Levulinic Acids; Liver; Phenobarbital; Protein Biosynthesis; Transcription, Genetic	1975
On the sequence of reactions leading to cytochrome P-450 synthesis-effect of drugs. The Journal of biological chemistry, 1975, Mar-25, Volume: 250, Issue:6 Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Apoproteins; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Endoplasmic Reticulum; Glycine; Heme; Iron; Liver; Male; Microsomes, Liver; Phenobarbital; Rats	1975
Characteristics of the induction of aldehyde dehydrogenase in rat liver. Archives of biochemistry and biophysics, 1975, Volume: 166, Issue:2 Topics: Aldehyde Oxidoreductases; Allylisopropylacetamide; Animals; Cycloheximide; Cytosol; Enzyme Induction; Heme; Liver; Phenobarbital; Rats; Species Specificity; Time Factors	1975
Cyclophosphamide and its metabolite acrolein. Some studies on their porphyrinogenic action in 17 day old chick embryo. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1992, Volume: 102, Issue:1 Topics: 5-Aminolevulinate Synthetase; Acrolein; Allylisopropylacetamide; Animals; Chick Embryo; Cyclophosphamide; Cytochrome P-450 Enzyme System; Enzyme Induction; Gestational Age; Liver; Molecular Structure; Phenobarbital; Porphyrins; Proadifen	1992
Metabolism and alkylating activity of thio-TEPA in rat liver slice incubation. Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:6 Topics: Alkylation; Allylisopropylacetamide; Animals; Dose-Response Relationship, Drug; In Vitro Techniques; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Thiotepa; Time Factors; Tissue Survival; Triethylenephosphoramide	1991
Experimental latent and acute porphyria in the non-fasted rat; preventive effect of propranolol. Scandinavian journal of clinical and laboratory investigation, 1991, Volume: 51, Issue:8 Topics: Acute Disease; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Coproporphyrins; Dicarbethoxydihydrocollidine; Feces; Male; Phenobarbital; Porphobilinogen; Porphyrias; Propranolol; Protoporphyrins; Rats; Rats, Inbred Strains	1991
L-Alanine: 4,5-dioxovalerate transaminase does not regulate heme synthesis in rat liver. Biochimica et biophysica acta, 1990, May-16, Volume: 1034, Issue:2 Topics: Alanine; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Chick Embryo; Dicarbethoxydihydrocollidine; Enzyme Induction; Heme; Hemin; Liver; Male; Phenobarbital; Porphyrins; Rats; Rats, Inbred Strains; Transaminases; Valerates	1990
The cDNA and protein sequence of a phenobarbital-induced chicken cytochrome P-450. The Journal of biological chemistry, 1986, Jul-15, Volume: 261, Issue:20 Topics: Allylisopropylacetamide; Amino Acid Sequence; Animals; Base Sequence; Biological Evolution; Chickens; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; DNA; DNA, Recombinant; Nucleic Acid Hybridization; Phenobarbital; Poly A; RNA; RNA, Messenger	1986
Role of xanthine oxidase in the interferon-mediated depression of the hepatic cytochrome P-450 system in mice. Cancer research, 1988, Apr-15, Volume: 48, Issue:8 Topics: Acetylcysteine; Aldehyde Oxidase; Aldehyde Oxidoreductases; Allopurinol; Allylisopropylacetamide; Animals; Azacitidine; Carboxymethylcellulose Sodium; Cytochrome P-450 Enzyme Inhibitors; Dithiothreitol; Ethylmorphine-N-Demethylase; Interferons; Liver; Male; Mice; Phenobarbital; Poly I-C; Polylysine; Tungsten; Tungsten Compounds; Xanthine Dehydrogenase; Xanthine Oxidase	1988
Effects of polychlorinated biphenyls on cytochrome P450 induction in the chick embryo hepatocyte culture. Archives of biochemistry and biophysics, 1989, Nov-15, Volume: 275, Issue:1 Topics: Allylisopropylacetamide; Animals; Cells, Cultured; Chick Embryo; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Hexachlorobenzene; Kinetics; Liver; Methylcholanthrene; Phenobarbital; Polychlorinated Biphenyls; Structure-Activity Relationship	1989
Regulation of genes associated with drug metabolism. Biochemical Society symposium, 1989, Volume: 55 Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Amino Acid Sequence; Animals; Chick Embryo; Cytochrome P-450 Enzyme System; Enzyme Activation; Gene Expression Regulation; Heme; Humans; Inactivation, Metabolic; Liver; Molecular Sequence Data; Phenobarbital; Rats; RNA, Messenger; Transcription, Genetic; Transcriptional Activation	1989
Effect of haem on cytochrome P-450 synthesis. Clinical and experimental pharmacology & physiology, 1989, Volume: 16, Issue:6 Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Gene Expression Regulation; Heme; Heptanoates; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; RNA, Messenger; Steroid 11-beta-Hydroxylase	1989
Heme may not be a positive regulator of cytochrome-P450 gene expression. European journal of biochemistry, 1989, Jan-02, Volume: 178, Issue:3 Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Benzoflavones; beta-Naphthoflavone; Clofibrate; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Gene Expression Regulation; Genes; Heme; Humans; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Reference Values; RNA, Messenger; Transcription, Genetic	1989
Drug induction of P450IIB1/IIB2 and 5-aminolevulinate synthase mRNAs in rat tissues. Biochimica et biophysica acta, 1989, Mar-01, Volume: 1007, Issue:2 Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Blotting, Northern; Cytochrome P-450 Enzyme System; Enzyme Induction; Kidney; Liver; Lung; Male; Phenobarbital; Rats; Rats, Inbred Strains; RNA, Messenger; Tissue Distribution	1989
Regulation of cytochrome P-450 messenger RNA and apoprotein levels by heme. The Journal of biological chemistry, 1987, Dec-15, Volume: 262, Issue:35 Topics: Allylisopropylacetamide; Amitrole; Animals; Apoproteins; Cobalt; Cytochrome P-450 Enzyme System; Gene Expression Regulation; Heme; Hemin; Male; Phenobarbital; Rats; RNA, Messenger	1987
N-alkylation of exogenous haem analogues caused by drugs in isolated hepatocytes. Structural isomerism and chirality of the resulting porphyrins. The Biochemical journal, 1986, Aug-15, Volume: 238, Issue:1 Topics: Acetamides; Allylisopropylacetamide; Animals; Benzoflavones; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Deuteroporphyrins; Dicarbethoxydihydrocollidine; In Vitro Techniques; Liver; Male; Mesoporphyrins; Phenobarbital; Porphyrins; Pyridines; Rats; Rats, Inbred Strains; Stereoisomerism	1986
Cytochrome P-450-dependent H2O2 production demonstrated in vivo. Influence of phenobarbital and allylisopropylacetamide. FEBS letters, 1986, Apr-07, Volume: 199, Issue:1 Topics: Acetamides; Allylisopropylacetamide; Animals; Catalase; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Enzyme Induction; Guinea Pigs; Hydrogen Peroxide; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Species Specificity	1986
Heterogeneous distribution of drug metabolism in elutriated rat hepatocytes. Biochemical pharmacology, 1985, May-01, Volume: 34, Issue:9 Topics: Allylisopropylacetamide; Animals; Centrifugation; Cytochrome P-450 Enzyme System; Flow Cytometry; Fluoresceins; In Vitro Techniques; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains	1985
Regulation of delta-aminolevulinic acid synthetase by drugs and steroids in isolated perfused rat liver. Enzyme, 1973, Volume: 16, Issue:1 Topics: 5-Aminolevulinate Synthetase; Acetamides; Allylisopropylacetamide; Animals; Dexamethasone; Drug Synergism; Enzyme Induction; Fasting; Glucose; Liver; Male; Perfusion; Phenobarbital; Pyridines; Rats; Time Factors; Tyrosine Transaminase	1973
Biochemical effects of 3,5-diethoxycarbonyl-1,4-dihydrocollidine in mouse liver. Biochemical pharmacology, 1974, Oct-01, Volume: 23, Issue:19 Topics: Allylisopropylacetamide; Aniline Compounds; Animals; Carbon Radioisotopes; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dicarboxylic Acids; Female; Heme; Iron Radioisotopes; Kinetics; Leucine; Lipid Metabolism; Liver; Mice; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; NADP; Organ Size; Phenobarbital; Phospholipids; Protein Biosynthesis; Pyridines; Ribonucleases; RNA	1974
Nitroreduction of 5-nitrofuran derivatives by rat liver xanthine oxidase and reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase. Biochemical pharmacology, 1974, Dec-15, Volume: 23, Issue:24 Topics: Acetamides; Allylisopropylacetamide; Animals; Carbon Radioisotopes; Chromatography, Ion Exchange; Cytochrome c Group; Cytochrome Reductases; Cytosol; Dialysis; Electron Transport; Female; Hydrazines; In Vitro Techniques; Liver; Methylcholanthrene; Microsomes, Liver; Milk; NADP; Nitrofurans; Nitrofurantoin; Oxidation-Reduction; Phenobarbital; Protein Binding; Rats; Thiazoles; Xanthine Oxidase	1974
Modification of the response of rats to lethal levels of ozone by enzyme-inducing agents. Toxicology and applied pharmacology, 1974, Volume: 27, Issue:2 Topics: Allylisopropylacetamide; Aminobenzoates; Animals; Enzyme Induction; Male; Methylcholanthrene; Oxidoreductases; Ozone; Phenobarbital; Phenothiazines; Polychlorinated Biphenyls; Rats; Time Factors	1974
Biochemical effects of the porphyrinogenic drug allylisopropylacetamide. A comparative study with phenobarbital. The Biochemical journal, 1973, Volume: 134, Issue:4 Topics: Acetamides; Allylisopropylacetamide; Animals; Carbon Radioisotopes; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Female; Heme; Liver; Microsomes, Liver; Organ Size; Phenobarbital; Phospholipids; Proteins; Rats; Ribonucleases; RNA	1973
Comparative study on induction of hepatic delta-aminolevulinate synthetase by different drugs. Enzyme, 1973, Volume: 16, Issue:1 Topics: 5-Aminolevulinate Synthetase; Acetamides; Allylisopropylacetamide; Animals; Bucladesine; Cells, Cultured; Chick Embryo; Cycloheximide; Cytosol; Dicarboxylic Acids; Enzyme Induction; Heme; Liver; Mitochondria, Liver; Phenobarbital; Pyridines; Rats; Species Specificity; Time Factors	1973
The effects of drugs on the activities of 5-aminolaevulinate synthetase and other enzymes in the pathway of haem biosynthesis. The Biochemical journal, 1972, Volume: 130, Issue:2 Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Dicarboxylic Acids; Esters; Griseofulvin; Heme; Liver; Mice; Phenobarbital; Phenylbutazone; Porphyrias; Pyridines; Rats	1972
Evidence against a regulatory role for heme oxygenase in hepatic heme synthesis. Biochimica et biophysica acta, 1973, May-28, Volume: 304, Issue:3 Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Heme; Liver; Male; Microsomes, Liver; Oxygenases; Phenobarbital; Rats; Spleen; Starvation	1973
Theophylline suppression of delta-aminolevulinic acid synthetase induction in chick embryo and rat livers. Biochemical and biophysical research communications, 1973, Aug-21, Volume: 53, Issue:4 Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Chick Embryo; Drug Interactions; Enzyme Induction; Etiocholanolone; Hydroxysteroids; In Vitro Techniques; Liver; Male; Phenobarbital; Pregnanediones; Rats; Theophylline; Time Factors; Xanthines	1973
Spectroscopic evidence of interaction between 2-allyl-2-isopropylacetamide and cytochrome P-450 of rat liver microsomes. Biochemical and biophysical research communications, 1973, Dec-10, Volume: 55, Issue:3 Topics: Acetamides; Allylisopropylacetamide; Animals; Binding Sites; Computers, Analog; Cytochrome P-450 Enzyme System; Hexobarbital; Male; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Regression Analysis; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors	1973
A model for the regulation of delta-aminolaevulinate synthetase induction in rat liver. The Biochemical journal, 1973, Volume: 134, Issue:4 Topics: 5-Aminolevulinate Synthetase; Adrenalectomy; Allylisopropylacetamide; Animals; Carbon Radioisotopes; Castration; Citrates; Cytochrome P-450 Enzyme System; Dactinomycin; Enzyme Induction; Female; Heme; Hydrocortisone; Iron Radioisotopes; Liver; Male; Microsomes, Liver; Models, Biological; Phenobarbital; Protein Binding; Rats	1973
Drug interactions in experimental hepatic porphyria. A model for the exacerbation by drugs of human variegate porphyria. Enzyme, 1973, Volume: 16, Issue:1 Topics: 5-Aminolevulinate Synthetase; Administration, Oral; Allylisopropylacetamide; Animals; Chickens; Cobalt; Dicarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Humans; Injections, Intraperitoneal; Levulinic Acids; Liver; Male; Mitochondria, Liver; Models, Biological; Phenobarbital; Porphobilinogen; Porphyrias; Pyridines; Rats; Species Specificity; Spectrometry, Fluorescence	1973
The effects of chemical porphyrogens and drugs on the activity of rat liver tryptophan pyrrolase. The Biochemical journal, 1973, Volume: 136, Issue:4 Topics: Acetamides; Allylisopropylacetamide; Animals; Apoproteins; Cytochrome P-450 Enzyme System; Dicarboxylic Acids; Griseofulvin; Heme; Humans; Hydrocortisone; Levulinic Acids; Liver; Male; Mental Disorders; Microsomes; Phenobarbital; Phenylbutazone; Porphyrias; Proadifen; Protein Precursors; Pyridines; Rats; Starvation; Time Factors; Tryptophan; Tryptophan Oxygenase	1973
Reaction schemes for the degradation of cytochromes P-450 by allyl-isopropylacetamide and fluroxene. Biochemical pharmacology, 1980, Oct-15, Volume: 29, Issue:20 Topics: Acetamides; Allylisopropylacetamide; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Ethers; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Rats	1980
Role of hepatic microsomal cytochrome P-450 in the toxicity of fluorinated ether anesthetics. Biochemical pharmacology, 1980, Volume: 29, Issue:24 Topics: Allylisopropylacetamide; Anesthetics; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Ethers; Male; Microsomes, Liver; Phenobarbital; Rats	1980
Reaction schemes for the degradation of cytochrome P-450 by allyl-iso-propylacetamide and fluroxene. Advances in experimental medicine and biology, 1981, Volume: 136 Pt B Topics: Acetamides; Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Ethers; Kinetics; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats	1981
Effect of drugs and hormones on rat liver dimethylaminoazobenzene reductase activity. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1982, Volume: 15, Issue:1 Topics: Allylisopropylacetamide; Amitrole; Animals; Cytochrome P-450 Enzyme System; Female; In Vitro Techniques; Methylcholanthrene; Microsomes, Liver; NADH, NADPH Oxidoreductases; p-Dimethylaminoazobenzene; Phenobarbital; Rats; Rats, Inbred Strains; Streptozocin; Thyroxine	1982
Serine and glycine-induced catalepsy in porphyric rats: an animal model for psychosis? Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:2 Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Catalepsy; Disease Models, Animal; Glycine; Humans; Male; Phenobarbital; Porphobilinogen; Porphyrias; Psychotic Disorders; Rats; Rats, Inbred Strains; Serine	1983
Formation of cytochrome P-450 containing haem or cobalt-protoporphyrin in liver homogenates of rats treated with phenobarbital and allylisopropylacetamide. The Biochemical journal, 1984, Sep-01, Volume: 222, Issue:2 Topics: Acetamides; Allylisopropylacetamide; Animals; Apoenzymes; Cytochrome P-450 Enzyme System; Heme; Immunoelectrophoresis; In Vitro Techniques; Liver; Male; Phenobarbital; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains; Spectrophotometry	1984
Evidence that 2-allyl-2-isopropylacetamide and phenobarbital induce the same cytochrome P-450 in cultured chick embryo hepatocytes. Biochemical and biophysical research communications, 1984, Dec-28, Volume: 125, Issue:3 Topics: Acetamides; Allylisopropylacetamide; Animals; Chick Embryo; Cytochrome P-450 Enzyme System; Enzyme Induction; Liver; Phenobarbital; Spectrophotometry; Time Factors	1984
Pharmacologic toxicity of cimetidine on hepatic and renal drug metabolism. Research communications in chemical pathology and pharmacology, 1984, Volume: 45, Issue:1 Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Cimetidine; Cytochrome P-450 Enzyme System; Heme Oxygenase (Decyclizing); Kidney; Liver; Male; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains	1984
Metabolism of estradiol in liver cell culture. Differential responses of C-2 and C-16 oxidations to drugs and other chemicals that induce selective species of cytochrome P-450. The Journal of clinical investigation, 1983, Volume: 72, Issue:4 Topics: Allylisopropylacetamide; Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Cell Count; Cells, Cultured; Chick Embryo; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Estradiol; Liver; Methylcholanthrene; Phenobarbital	1983
Influence of allylisopropylacetamide and phenobarbital treatment on in vivo antipyrine metabolite formation in rats. Xenobiotica; the fate of foreign compounds in biological systems, 1983, Volume: 13, Issue:8 Topics: Acetamides; Allylisopropylacetamide; Animals; Antipyrine; Biotransformation; Half-Life; Male; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors	1983
Evidence that 2-allyl-2-isopropylacetamide, phenobarbital and 3,5-diethoxycarbonyl-1,4-dihydrocollidine induce the same cytochrome P450 mRNA in chick embryo liver. European journal of biochemistry, 1983, Nov-02, Volume: 136, Issue:2 Topics: Acetamides; Allylisopropylacetamide; Animals; Chemical Phenomena; Chemistry; Chick Embryo; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; DNA; Enzyme Induction; Liver; Nucleic Acid Hybridization; Phenobarbital; Pyridines; RNA, Messenger	1983
The allylisopropylacetamide and novonal prosthetic heme adducts. Molecular pharmacology, 1984, Volume: 25, Issue:2 Topics: Acetamides; Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Heme; Liver; Magnetic Resonance Spectroscopy; Phenobarbital; Rats; Structure-Activity Relationship	1984
Studies on the autoinactivation behavior of pure, reconstituted phenobarbital-induced cytochrome P-450 isozyme from rat liver. The Journal of biological chemistry, 1980, Oct-10, Volume: 255, Issue:19 Topics: Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Isoenzymes; Kinetics; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Phenobarbital; Rats	1980
The effect in vivo and in vitro of allylisopropylacetamide on the content of hepatic microsomal cytochrome P-450 2 of phenobarbital treated rabbits. Biochemical and biophysical research communications, 1983, Mar-29, Volume: 111, Issue:3 Topics: Acetamides; Allylisopropylacetamide; Animals; Chemical Phenomena; Chemistry; Cytochrome P-450 Enzyme System; Heme; In Vitro Techniques; Microsomes, Liver; NADP; Phenobarbital; Rabbits	1983
Factors affecting haem degradation in rat brain. Biochemical pharmacology, 1980, Jun-01, Volume: 29, Issue:11 Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Biotransformation; Brain; Female; Heme; Heme Oxygenase (Decyclizing); In Vitro Techniques; Lead; Liver; Phenobarbital; Rats	1980
Control of delta-aminolaevulinate synthase and haem oxygenase in chronic-iron-overloaded rats. The Biochemical journal, 1981, Oct-15, Volume: 200, Issue:1 Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Cobalt; Heme; Heme Oxygenase (Decyclizing); Iron; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains	1981
Kinetic evidence for heterogeneous responsiveness of mixed function oxidase isozymes to inhibition and induction by allylisopropylacetamide in chick embryo liver. The Journal of biological chemistry, 1982, Oct-10, Volume: 257, Issue:19 Topics: 7-Alkoxycoumarin O-Dealkylase; Acetamides; Allylisopropylacetamide; Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrene Hydroxylase; Chick Embryo; Cycloheximide; Cytochrome P-450 Enzyme System; Enzyme Induction; Isoenzymes; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Oxygenases; Phenobarbital	1982
An in vitro model demonstrating the glucose effect and the influence of fasting on porphyrin metabolism. FEBS letters, 1982, Feb-22, Volume: 138, Issue:2 Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Chick Embryo; Dicarbethoxydihydrocollidine; Fasting; Glucose; Phenobarbital; Porphyrins; Time Factors	1982
[Changes in liver microsomal enzymes and the synthesis of delta-aminolevulinic acid in short-term exposure of rabbits to allylisopropylacetamide, hexachlorobenzene and phenobarbital]. Eksperimentalna meditsina i morfologiia, 1982, Volume: 21, Issue:3 Topics: Acetamides; Allylisopropylacetamide; Aminolevulinic Acid; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Enzyme Induction; Hexachlorobenzene; Levulinic Acids; Microsomes, Liver; Phenobarbital; Rabbits; Time Factors	1982
Effects of porphyrinogenic (porphyria-producing) agents on avian embryonic hepatic glutathione S-transferase activity. Biochemical and biophysical research communications, 1981, May-15, Volume: 100, Issue:1 Topics: Acetamides; Allylisopropylacetamide; Animals; Chick Embryo; Cyproterone; Cytochrome P-450 Enzyme System; Cytosol; Glutathione Transferase; Heme; Liver; Phenobarbital; Porphyrias	1981
Determination of partition ratios for allylisopropylacetamide during suicidal processing by a phenobarbital-induced cytochrome P-450 isozyme from rat liver. The Journal of biological chemistry, 1981, Aug-25, Volume: 256, Issue:16 Topics: Acetamides; Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; DNA; Enzyme Induction; Isoenzymes; Kinetics; Microsomes, Liver; Phenobarbital; Rats	1981
In vivo effects of the cytochrome P-450 suicide substrate 2-isopropyl-4-pentenamide (allylisopropylacetamide) on the disposition and metabolic pattern of propranolol. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:1 Topics: Acetamides; Allylisopropylacetamide; Animals; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dogs; Drug Interactions; Enzyme Induction; Kinetics; Male; Phenobarbital; Propranolol; Propylene Glycol; Propylene Glycols	1981
Use of 2-allyl-2-isopropylacetamide as a catalytic site probe for rabbit cytochrome P-450. Research communications in chemical pathology and pharmacology, 1981, Volume: 33, Issue:3 Topics: Acetamides; Allylisopropylacetamide; Animals; Binding Sites; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains	1981
Microsomal NADPH-dependent lipid peroxidation does not require the presence of intact cytochrome P450. Biochemical and biophysical research communications, 1980, Aug-29, Volume: 95, Issue:4 Topics: Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Heme; In Vitro Techniques; Lipid Peroxides; Male; Malondialdehyde; Methylcholanthrene; Microsomes, Liver; NADP; Phenobarbital; Pregnenolone Carbonitrile; Rats	1980
Structural and functional reconstitution of hepatic cytochrome P-450 in vivo. Reversal of allylisopropylacetamide-mediated destruction of the hemoprotein by exogenous heme. The Journal of biological chemistry, 1980, Nov-10, Volume: 255, Issue:21 Topics: Acetamides; Allylisopropylacetamide; Animals; Cycloheximide; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Ethylmorphine-N-Demethylase; Heme; Kinetics; Male; Microsomes, Liver; Phenobarbital; Rats	1980
Evidence that in chick embryos destruction of hepatic microsomal cytochrome P-450 haem is a general mechanism of induction of delta-aminolaevulinate synthase by porphyria-causing drugs. The Biochemical journal, 1980, Sep-15, Volume: 190, Issue:3 Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Chick Embryo; Cytochrome P-450 Enzyme System; Deferoxamine; Dicarbethoxydihydrocollidine; Enzyme Induction; Heme; Hemin; Microsomes, Liver; Phenobarbital; Porphyrias; Proadifen	1980
Inactivation of phenobarbital-inducible rabbit-liver microsomal cytochrome P-450 by allylisopropylacetamide: impact on electron transfer. Biochimica et biophysica acta, 1993, Apr-05, Volume: 1142, Issue:1-2 Topics: Allylisopropylacetamide; Amino Acids; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochromes b5; Electron Transport; Enzyme Induction; Heme; Microsomes, Liver; NAD; NADP; Phenobarbital; Proteins; Rabbits	1993