alloxan has been researched along with metformin in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.17) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 2 (8.33) | 29.6817 |
| 2010's | 14 (58.33) | 24.3611 |
| 2020's | 6 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kimura, M; Suzuki, J | 1 |
| Cenani, A; Güven, M; Hatemi, H; Kanigür-Sultuybek, G; Onaran, I; Tezcan, V | 1 |
| Li, J; Liu, M; Liu, Z; Wang, M; Zeng, Z | 1 |
| Choi, YH; Lee, I; Lee, MG | 1 |
| Aragão, DM; da Costa, JC; Garcia, RM; Guarize, L; Lanini, J; Scio, E | 1 |
| Birman, E; Blouin, MJ; Carboni, JM; David, S; Dool, CJ; Gottardis, M; Mashhedi, H; Pollak, M; Zakikhani, M; Zhao, Y | 1 |
| Abd el-Latif, FF; Khalifa, M; Sayed, AA | 1 |
| Ancona-Leon, G; Cardena-Arredondo, C; Diaz-Cedillo, F; Figueroa-Valverde, L; Garcia-Cervera, E; Lopez-Ramos, M; Pool-Gomez, E | 1 |
| Nayak, AK; Pal, D | 1 |
| Nayak, AK; Pal, D; Santra, K | 1 |
| Irekpita, JE; Ojo, OO; Olayaki, LA; Yakubu, MT | 1 |
| Ferdaus, R; Jahan, L; Shaheen, SM | 1 |
| Chinwuba Okoye, T; Chukwunonso Obi, B; Nonye Igwe, C; Okpashi, VE; Olisah Alumanah, E | 1 |
| Darvhekar, V; Jyotishi, SG; Mazumder, PM; Shelke, PG; Tripathi, AS | 1 |
| Heidarian, E; Kheiri, S; Rafieian-Kopaei, M; Rahimi-Madiseh, M | 1 |
| Cavalcante, MR; Coutinho, HDM; de Albuquerque, TR; de Barros Viana, GS; de Menezes, IRA; de Oliveira Garcia, FA; Felipe, CFB; Garcia, TR; Menezes, CDA; Moreira, AC; Pinheiro, PG; Santos, ES; Silva, TF | 1 |
| Ifeanacho, MO; Ikewuchi, CC; Ikewuchi, JC | 1 |
| Aa, AB; Ga, A; Om, J; Ts, E | 1 |
| Ghumman, SA; Noreen, S; Tul Muntaha, S | 1 |
| Achyut, A; Amir, Z; Amna, N; Fazle, R; Irfan, U; Shafiq Ur, R | 1 |
| Hashim, WS; Qader, SM; Yasin, YS | 1 |
| Hussain, F; Khan, M; Parvez, M | 1 |
| Al-Sarray, RAH; Al-Shaeli, SJJ | 1 |
| Almuttairi, RS | 1 |
1 trial(s) available for alloxan and metformin
| Article | Year |
|---|---|
Metformin and Bee Venom: a Comparative Detection of Histological Alteration of the Pancreas and Systemic Inflammatory Markers in Diabetic Mice.
Topics: Alloxan; Animals; Bee Venoms; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Insulin; Interleukin-10; Interleukin-6; Male; Metformin; Mice; Pancreas; Tumor Necrosis Factor-alpha | 2022 |
23 other study(ies) available for alloxan and metformin
| Article | Year |
|---|---|
[Hypoglycemic effects of the blended Chinese traditional medicines in genetically and chemically diabetic mice].
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glyburide; Hypoglycemic Agents; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Metformin; Mice; Tolbutamide | 1984 |
The effect of metformin on insulin receptors and lipid peroxidation in alloxan and streptozotocin induced diabetes.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Insulin; Lipid Peroxidation; Liver; Male; Metformin; Rats; Receptor, Insulin; Streptozocin | 1995 |
The antidiabetic effects of cysteinyl metformin, a newly synthesized agent, in alloxan- and streptozocin-induced diabetic rats.
Topics: Alloxan; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Insulin; Male; Metformin; Organ Size; Pancreas; Rats; Rats, Wistar; Streptozocin; Triglycerides | 2008 |
Effects of diabetes mellitus induced by alloxan on the pharmacokinetics of metformin in rats: restoration of pharmacokinetic parameters to the control state by insulin treatment.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Insulin; Male; Metabolic Clearance Rate; Metformin; Rats; Rats, Sprague-Dawley | 2008 |
Hypoglycemic effects of Cecropia pachystachya in normal and alloxan-induced diabetic rats.
Topics: Alloxan; Animals; Antioxidants; Ascorbic Acid; Blood Glucose; Cecropia Plant; Diabetes Mellitus; Diabetes Mellitus, Type 2; Flavonoids; Free Radical Scavengers; Glucose Tolerance Test; Glucosides; Glyburide; Hypoglycemic Agents; Male; Medicine, Traditional; Metformin; Phenols; Plant Extracts; Rats; Rats, Wistar | 2010 |
IGF1/insulin receptor kinase inhibition by BMS-536924 is better tolerated than alloxan-induced hypoinsulinemia and more effective than metformin in the treatment of experimental insulin-responsive breast cancer.
Topics: Alloxan; Antineoplastic Agents; Benzimidazoles; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Evaluation, Preclinical; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Metformin; Protein Kinase Inhibitors; Pyridones; Receptor, IGF Type 1; Treatment Outcome | 2011 |
Fenugreek attenuation of diabetic nephropathy in alloxan-diabetic rats: attenuation of diabetic nephropathy in rats.
Topics: Alloxan; Animals; Anti-Inflammatory Agents; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glutathione; Interleukin-6; Kidney; Lipid Peroxidation; Malondialdehyde; Metformin; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rosiglitazone; Superoxide Dismutase; Thiazolidinediones; Trigonella | 2012 |
Glibenclamide-pregnenolone derivative has greater hypoglycemic effects and biodistribution than glibenclamide-OH in alloxan-rats.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drug Combinations; Female; Glyburide; Hypoglycemic Agents; Metformin; Pregnenolone; Rats; Rats, Wistar; Tissue Distribution | 2012 |
Formulation optimization and evaluation of jackfruit seed starch-alginate mucoadhesive beads of metformin HCl.
Topics: Alginates; Alloxan; Animals; Artocarpus; Calcium Chloride; Delayed-Action Preparations; Diabetes Mellitus, Experimental; Drug Compounding; Factor Analysis, Statistical; Gels; Glucuronic Acid; Hexuronic Acids; Hydrogen-Ion Concentration; Hypoglycemic Agents; Kinetics; Male; Metformin; Rats; Seeds; Starch; Water | 2013 |
Tamarind seed polysaccharide-gellan mucoadhesive beads for controlled release of metformin HCl.
Topics: Administration, Oral; Alloxan; Animals; Diabetes Mellitus, Experimental; Drug Carriers; Hypoglycemic Agents; Intestinal Mucosa; Metformin; Polysaccharides; Polysaccharides, Bacterial; Seeds; Tamarindus | 2014 |
Methanolic extract of Moringa oleifera leaves improves glucose tolerance, glycogen synthesis and lipid metabolism in alloxan-induced diabetic rats.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucose Tolerance Test; Glycogen; Glycogen Synthase; Hypoglycemic Agents; Insulin; Lipid Metabolism; Male; Metformin; Methanol; Moringa oleifera; Plant Extracts; Plant Leaves; Rats; Rats, Wistar | 2015 |
A therapeutic TDS patch of Metformin from a HPMC-PVA blend studied with a biological membrane of fish-swim bladder: An approach for dermal application in NIDDM.
Topics: Administration, Cutaneous; Alloxan; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Hypoglycemic Agents; Hypromellose Derivatives; Male; Metformin; Mice; Polyvinyl Alcohol | 2015 |
Comparative Study of the Antioxidant Effects of Metformin, Glibenclamide, and Repaglinide in Alloxan-Induced Diabetic Rats.
Topics: Alloxan; Animals; Antioxidants; Biomarkers; Blood Glucose; Carbamates; Catalase; Diabetes Complications; Diabetes Mellitus, Experimental; Glutathione; Glyburide; Hypoglycemic Agents; Lipid Peroxidation; Male; Malondialdehyde; Metformin; Oxidative Stress; Piperidines; Rats; Superoxide Dismutase | 2016 |
Influence of Musa sapientum L. on pharmacokinetic of metformin in diabetic gastroparesis.
Topics: Alloxan; Animals; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Gastroparesis; Male; Metformin; Musa; Plant Extracts; Rats, Sprague-Dawley | 2016 |
Effect of hydroalcoholic Allium ampeloprasum extract on oxidative stress, diabetes mellitus and dyslipidemia in alloxan-induced diabetic rats.
Topics: Allium; Alloxan; Animals; Antioxidants; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Dyslipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Kidney; Liver; Male; Metformin; Oxidative Stress; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Triglycerides | 2017 |
Murraya paniculata (L.) (Orange Jasmine): Potential Nutraceuticals with Ameliorative Effect in Alloxan-Induced Diabetic Rats.
Topics: Alloxan; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Dietary Supplements; Glyburide; Hypoglycemic Agents; India; Liver; Male; Medicine, Traditional; Metformin; Murraya; Pancreas; Plant Extracts; Rats; Rats, Wistar; Triglycerides | 2017 |
Restoration of plasma markers of liver and kidney functions/integrity in alloxan-induced diabetic rabbits by aqueous extract of Pleurotus tuberregium sclerotia.
Topics: Alloxan; Animals; Biomarkers; Blood Urea Nitrogen; Chromatography, Gas; Diabetes Mellitus, Experimental; Diuretics; Dose-Response Relationship, Drug; Hypoglycemic Agents; Kidney; Liver; Metformin; Plant Extracts; Pleurotus; Rabbits | 2017 |
Preliminary phytochemical screening, antioxidant and antihyperglycaemic activity of Moringa oleifera leaf extracts.
Topics: Alloxan; Animals; Antioxidants; Ascorbic Acid; Biphenyl Compounds; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Ethanol; Female; Hypoglycemic Agents; Male; Metformin; Methanol; Moringa oleifera; Picrates; Plant Extracts; Plant Leaves; Rats, Wistar; Solvents; Water | 2017 |
Linum usitatissimum seed mucilage-alginate mucoadhesive microspheres of metformin HCl: Fabrication, characterization and evaluation.
Topics: Alginates; Alloxan; Animals; Diabetes Mellitus, Experimental; Drug Compounding; Drug Liberation; Flax; Hypoglycemic Agents; Male; Metformin; Microspheres; Plant Mucilage; Rats; Seeds | 2020 |
Detailed approach toward the anti-hyperglycemic potential of Sterculia diversifolia G. Don against alloxan-induced in vivo hyperglycemia model.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Humans; Hyperglycemia; Hypoglycemic Agents; Kaempferols; Metformin; Mice; Phytochemicals; Plant Extracts; Quercetin; Sterculia | 2022 |
Evaluation of metformin performance on alloxan-induced diabetic rabbits.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Glutathione; Hypoglycemic Agents; Metformin; Rabbits | 2022 |
Crude extract from
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Euphorbia; Gliclazide; Glyburide; Hypoglycemic Agents; Insulin; Metformin; Plant Extracts; Rats | 2023 |
The Effects of Metformin Treatment on Diabetic Albino Rats' Pancreas, Liver, and Kidney Histology.
Topics: Alloxan; Animals; Diabetes Mellitus; Kidney; Liver; Male; Metformin; Mice; Pancreas; Rats; Rodent Diseases; Water | 2023 |