Page last updated: 2024-09-03

allosamidin and acetylglucosamine

allosamidin has been researched along with acetylglucosamine in 86 studies

Compound Research Comparison

Studies (allosamidin)	Trials (allosamidin)	Recent Studies (post-2010) (allosamidin)	Studies (acetylglucosamine)	Trials (acetylglucosamine)	Recent Studies (post-2010) (acetylglucosamine)
88	0	14	5,674	31	2,001

Protein Interaction Comparison

Protein	Taxonomy	acetylglucosamine (IC50)
Cytochrome P450 3A4	Homo sapiens (human)	1.9953
Cannabinoid receptor 1	Rattus norvegicus (Norway rat)	2.5119
Killer cell lectin-like receptor subfamily B member 1A	Rattus norvegicus (Norway rat)	2.2536

Research

Studies (86)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (5.81)	18.7374
1990's	29 (33.72)	18.2507
2000's	37 (43.02)	29.6817
2010's	14 (16.28)	24.3611
2020's	1 (1.16)	2.80

Authors

Authors	Studies
Gooday, GW; Milewski, S; O'Donnell, RW	1
Calvo-Méndez, C; López-Romero, E; Villagómez-Castro, JC	1
Glover, LA; McNab, R	1
Lopez-Romero, E; Pedraza-Reyes, M	1
Nishimoto, Y; Sakuda, S; Takayama, S; Yamada, Y	1
Adams, DJ; Dickinson, K; Hitchcock, CA; Keer, V	2
Butler, AR; Gooday, GW; Martin, VJ; O'Donnell, RW; Stark, MJ	1
Peter, MG; Schweikart, F	1
Bowers, B; Cabib, E; Sburlati, A; Silverman, SJ	1
Brydon, LJ; Chappell, LH; Gooday, GW	1
Doolin, LE; Fukuda, DS; McGowan, MJ; Mynderse, JS; Somers, PJ; Yao, RC	1
Isogai, A; Matsumoto, S; Sakuda, S; Suzuki, A	1
Armand, S; Dijkstra, BW; Henrissat, B; Isogai, A; Kalk, KH; Terwisscha van Scheltinga, AC	1
Adams, DJ; Escott, GM	1
Robbins, PW; Semino, CE	1
Kinoshita, M; Sakuda, S; Yamada, Y; Zhou, ZY	1
Blaak, H; Henrissat, B; Schnellmann, J; Schrempf, H; Walter, S	1
Arnold, K; Brydon, LJ; Chappell, LH; Gooday, GW	1
Aikawa, M; Kaslow, DC; Shahabuddin, M; Toyoshima, T	1
Alexander, IJ; Gooday, GW; Hodge, A	1
Izumida, H; Nishijima, M; Nomoto, AM; Sano, H; Takadera, T	1
López-Romero, E; Villagómez-Castro, JC	1
Blattner, R; Furneaux, RH; Lynch, GP	1
Sakuda, S; Spindler, KD; Spindler-Barth, M	1
Modi, GB; Pereira, ST; Pimenta, PF; Sacks, DL; Shahabuddin, M	1
Brameld, KA; Goddard, WA; Imperiali, B; Shrader, WD	1
Gooday, GW; Sampson, MN	1
Biró, S; Karaffa, L; Karányi, Z; Pócsi, I; Pusztahelyi, T; Sándor, E; Szentirmai, A	1
Sakuda, S; Sakurada, M	1
Odds, FC; Overdijk, B; Van Steijn, GJ	1
Brameld, KA; Dave, SK; Fidock, DA; Hayward, R; Specht, CA; Vinetz, JM; Xu, B	1
Kanai, R; Kawase, T; Mitsutomi, M; Miyashita, K; Sakuda, S; Tanabe, T; Watanabe, T	1
Bortone, K; Cox, R; Ernst, S; Hollis, T; Monzingo, AF; Robertus, JD	1
Bhushan, B	1
Allende, ML; Semino, CE	1
Spindler, KD; Spindler-Barth, M	1
Barends, T; Beintema, JJ; Bokma, E; Dijkstr, BW; Terwissch van Scheltingab, AC	1
Ikeda, H; Kakinuma, K; Nagasawa, H; Sakuda, S; Sugiyama, Y; Takao, H; Yamada, Y; Zhou, ZY	1
De Boer, W; Klein Gunnewiek, PJ; Kowalchuk, GA; Van Veen, JA	1
Eijsink, VG; Gåseidnes, S; Komander, D; Peter, MG; Synstad, B; van Aalten, DM	1
Emri, T; Leiter, E; Majoros, L; Pócsi, I; Pusztahelyi, T; Sámi, L; Szabó, B	1
Bortone, K; Ernst, S; Monzingo, AF; Robertus, JD	1
Sakuda, S	1
Germer, A; Kleinpeter, E; Peter, MG	1
Aksoy, S; Cheng, Q; Li, CB; Narashimhan, S; Yan, J	1
Eggleston, I; Eijsink, VG; Houston, DR; Synstad, B; van Aalten, DM	1
Germer, A; Kleinpeter, E; Klod, S; Peter, MG	1
Papanikolau, Y; Petratos, K; Tavlas, G; Vorgias, CE	1
Andronopoulou, E; Vorgias, CE	1
Aerts, JM; Boot, RG; Houston, DR; Rao, FV; Sakuda, S; van Aalten, DM	1
Liu, HM; Wang, S; Zhang, F	1
Anamnart, S; Kuzuyama, T; Matsuura, H; Nagasawa, H; Nakayama, J; Nihira, T; Okamoto, S; Sakuda, S; Seto, H; Suzuki, A; Wang, Q; Yamada, Y; Zhou, ZY	1
Eijsink, VG; Houston, DR; Peter, MG; Rao, FV; Synstad, B; Vaaje-Kolstad, G; van Aalten, DM	1
Kawachi, R; Koike, Y; Nagasawa, H; Nishio, T; Oku, T; Sakuda, S; Watanabe, Y	1
Karasuda, S; Koga, D; Kono, M; Sakuda, S; Yamamoto, K	1
Chen, NY; Elias, JA; Hu, X; Rabach, L; Rabach, M; Zheng, T; Zhu, Z	1
Andersen, OA; Dixon, MJ; Eggleston, IM; van Aalten, DM	1
Brurberg, MB; Clarke, JL; Eijsink, VG; Hoell, IA; Klemsdal, SS	1
Dubois, F; Giordanengo, P; Laberche, JC; Saguez, J; Sangwan-Norreel, BS; Vincent, C	1
Kawachi, R; Nagasawa, H; Nakanishi, E; Ohira, T; Sakuda, S; Suzuki, S	1
Horinouchi, S; Kawachi, R; Nagasawa, H; Nakanishi, E; Ohira, T; Ohnishi, Y; Sakuda, S; Suzuki, S	1
Hurtado-Guerrero, R; van Aalten, DM	1
Cederkvist, FH; Eijsink, VG; Karlsen, V; Sakuda, S; Saua, SF; Sørlie, M	1
Furihata, K; Horinouchi, S; Miyamoto, K; Nagasawa, H; Nakanishi, E; Ohnishi, Y; Sakuda, S; Suzuki, S; Tsujibo, H; Watanabe, T	1
Bucolo, C; Drago, F; Maltese, A; Musumeci, M; Musumeci, S	1
Chu, HY; Sun, CC; Zhang, HX; Zhao, YS; Zheng, QC	1
Chopra, R; Czerwinski, R; Fitz, L; Fleming, M; Joseph-McCarthy, D; Kriz, R; Krykbaev, R; Lin, L; Mosyak, L; Olland, AM; Presman, E; Schlingmann, G; Somers, W; Stahl, M; Strand, J	1
Fukamizo, T; Nakano, S; Sakuda, S; Takenaka, Y; Tamoi, M	1
Hisamori, D; Matsuda, S; Sattabongkot, J; Takeo, S; Tsuboi, T; Vinetz, J	1
Eguchi-Tsuda, M; Inoue, H; Kan-O, K; Kita, Y; Matsumoto, K; Matsumoto, T; Moriwaki, A; Nagasawa, H; Nakanishi, Y; Nakano, T; Noda, N; Sakuda, S; Sato, Y; Shimizu, T	1
Dennhart, N; Fujiwara, M; Fukamizo, T; Hayashi, H; Letzel, T; Ohnuma, T; Onaga, S; Sakuda, S; Taira, T	1
Baban, J; Eijsink, VG; Fjeld, S; Sakuda, S; Sørlie, M	1
Inoue, H; Kikuchi, N; Matsumoto, T; Muraoka, S; Nagasawa, H; Noda, N; Sakuda, S; Sato, Y; Suzuki, S	1
Li, Z; Liu, T; Qian, X; Wang, Y; Yang, Q	1
Cherqui, A; De Pauw, E; Dommès, J; Francis, F; Giordanengo, P; Haubruge, E; Saguez, J; Vandermoten, S; Versali, MF; Vincent, C	1
Huang, G	1
Boisvert, WA; Egashira, K; Han, X; Ichiki, T; Kitamoto, S; McCurdy, S; Sakuda, S; Sunagawa, K	1
Inoue, H; Nagasawa, H; Sakuda, S	1
Barghini, P; Crognale, S; Fenice, M; Garzillo, AM; Moscatelli, D	1
Nagasawa, H; Sakuda, S; Suzuki, S	1
Aceves, S; Broide, DH; Cho, JY; Miller, M; Pham, A; Rosenthal, P; Sakuda, S	1
Chen, X; Huang, G; Mei, X; Peng, D; Tang, Q; Xiao, F	1
Fukamizo, T; Kanda, Y; Numata, T; Ohnuma, T; Osawa, T; Sakuda, S; Taira, T; Umemoto, N	1
Huang, G; Huang, H	1
Gore, ST; Lakshminarasimhan, A; Mukherjee, S; Valiyaparambil, A; Viswanath, VK	1

Reviews

8 review(s) available for allosamidin and acetylglucosamine

Article	Year
Inhibitors of chitinases. EXS, 1999, Volume: 87 Topics: Acetylglucosamine; Animals; Bacteria; Cations, Divalent; Chitinases; Enzyme Inhibitors; Fungi; Peptides, Cyclic; Plants; Trisaccharides	1999
Searching for new-type antifungal drugs (an outline for possible new strategies). Acta microbiologica et immunologica Hungarica, 2001, Volume: 48, Issue:3-4 Topics: Acetylglucosamine; Amino Acid Sequence; Antifungal Agents; Chitinases; Drug Design; Enzyme Inhibitors; Fungal Proteins; Fungi; Glutathione; Molecular Sequence Data; Penicillium chrysogenum; Signal Transduction; Trisaccharides	2001
Natural product family 18 chitinase inhibitors. Natural product reports, 2005, Volume: 22, Issue:5 Topics: Acetylglucosamine; Biological Factors; Chitinases; Dipeptides; Disulfides; Enzyme Inhibitors; Molecular Structure; Peptides, Cyclic; Proline; Trisaccharides; Tyrosine; Xanthines	2005
Recent progress on synthesis and activities of allosamidin and its analogues. Mini reviews in medicinal chemistry, 2012, Volume: 12, Issue:7 Topics: Acetylglucosamine; Chemistry Techniques, Synthetic; Enzyme Inhibitors; Trisaccharides	2012
Novel biological activities of allosamidins. Molecules (Basel, Switzerland), 2013, Jun-13, Volume: 18, Issue:6 Topics: Acetylglucosamine; Animals; Anti-Asthmatic Agents; Chitinases; Humans; Secondary Metabolism; Streptomyces; Trisaccharides	2013
High-efficient synthesis and biological activities of allosamidins. Journal of enzyme inhibition and medicinal chemistry, 2015, Volume: 30, Issue:6 Topics: Acetylglucosamine; Animals; Antifungal Agents; Bombyx; Carbohydrate Conformation; Chitinases; Enzyme Inhibitors; Fungi; Insecticides; Spodoptera; Trisaccharides	2015
Synthesis, antiasthmatic, and insecticidal/antifungal activities of allosamidins. Journal of enzyme inhibition and medicinal chemistry, 2019, Volume: 34, Issue:1 Topics: Acetylglucosamine; Animals; Anti-Asthmatic Agents; Antifungal Agents; Asthma; Fungi; Humans; Insecticides; Molecular Conformation; Moths; Streptomyces; Trisaccharides	2019
Plasmodium chitinases: revisiting a target of transmission-blockade against malaria. Protein science : a publication of the Protein Society, 2021, Volume: 30, Issue:8 Topics: Acetylglucosamine; Amino Acid Sequence; Animals; Antimalarials; Chitinases; Culicidae; Enzyme Inhibitors; Malaria; Mosquito Vectors; Plasmodium; Protozoan Proteins; Sequence Alignment; Trisaccharides	2021

Other Studies

78 other study(ies) available for allosamidin and acetylglucosamine

Article	Year
Chemical modification studies of the active centre of Candida albicans chitinase and its inhibition by allosamidin. Journal of general microbiology, 1992, Volume: 138, Issue:12 Topics: Acetylglucosamine; Aspartic Acid; Binding Sites; Binding, Competitive; Candida albicans; Chitinases; Diethyl Pyrocarbonate; Ethyldimethylaminopropyl Carbodiimide; Glutamates; Glutamic Acid; Kinetics; Phenylglyoxal; Sulfhydryl Reagents; Trisaccharides	1992
Chitinase activity in encysting Entamoeba invadens and its inhibition by allosamidin. Molecular and biochemical parasitology, 1992, Volume: 52, Issue:1 Topics: Acetylglucosamine; Animals; Chitin; Chitinases; Entamoeba; Hydrolysis; Kinetics; Substrate Specificity; Trisaccharides	1992
Inhibition of Neurospora crassa cytosolic chitinase by allosamidin. FEMS microbiology letters, 1991, Jul-15, Volume: 66, Issue:1 Topics: Acetylglucosamine; Chitinases; Cytosol; Kinetics; Neurospora crassa; Trisaccharides	1991
Chitinase activity in germinating cells of Mucor rouxii. Antonie van Leeuwenhoek, 1991, Volume: 59, Issue:3 Topics: Acetylglucosamine; Chitinases; Hydrolysis; Mucor; Subcellular Fractions; Substrate Specificity; Trisaccharides	1991
Isolation and characterization of new allosamidins. The Journal of antibiotics, 1991, Volume: 44, Issue:7 Topics: Acetylglucosamine; Antifungal Agents; Candida albicans; Chitinases; Magnetic Resonance Spectroscopy; Molecular Structure; Saccharomyces cerevisiae; Spectrometry, Mass, Fast Atom Bombardment; Streptomyces; Trichoderma; Trisaccharides	1991
Microsomal chitinase activity from Candida albicans. Biochimica et biophysica acta, 1991, Jan-23, Volume: 1073, Issue:1 Topics: Acetylglucosamine; Candida albicans; Cell Compartmentation; Centrifugation, Density Gradient; Chitin Synthase; Chitinases; Cytosol; Microsomes; Solubility; Trisaccharides; Trypsin	1991
Kluyveromyces lactis toxin has an essential chitinase activity. European journal of biochemistry, 1991, Jul-15, Volume: 199, Issue:2 Topics: Acetylglucosamine; Amino Acid Sequence; Cell Cycle; Chitinases; Genotype; Killer Factors, Yeast; Kluyveromyces; Macromolecular Substances; Molecular Sequence Data; Mycotoxins; Saccharomyces cerevisiae; Sequence Homology, Nucleic Acid; Trisaccharides	1991
Chitin biosynthesis enhancement by the endochitinase inhibitor allosamidin. Biological chemistry Hoppe-Seyler, 1990, Volume: 371, Issue:6 Topics: Acetylglucosamine; Animals; Artemia; Carbohydrate Sequence; Cell Membrane; Chitin; Chitin Synthase; Chitinases; Glucosamine; Glucosyltransferases; Molecular Sequence Data; Trisaccharides	1990
Chitin synthase 1, an auxiliary enzyme for chitin synthesis in Saccharomyces cerevisiae. The Journal of cell biology, 1989, Volume: 108, Issue:5 Topics: Acetylglucosamine; Antifungal Agents; Cell Cycle; Chitin; Chitin Synthase; Chitinases; Glucosyltransferases; Hydrogen-Ion Concentration; Kinetics; Pyrimidine Nucleosides; Saccharomyces cerevisiae; Trisaccharides	1989
Chitinase activity from Candida albicans and its inhibition by allosamidin. Journal of general microbiology, 1989, Volume: 135, Issue:6 Topics: Acetylglucosamine; Candida albicans; Chitin; Chitinases; Fungal Proteins; Glucosamine; Hydrogen-Ion Concentration; Microbiological Techniques; Temperature; Trisaccharides	1989
Chitinase in female Onchocerca gibsoni and its inhibition by allosamidin. Molecular and biochemical parasitology, 1988, Volume: 29, Issue:2-3 Topics: Acetylglucosamine; Animals; Chitinases; Female; Glucosamine; Onchocerca; Trisaccharides	1988
Method for the detection and quantitation of chitinase inhibitors in fermentation broths; isolation and insect life cycle effect of A82516. The Journal of antibiotics, 1987, Volume: 40, Issue:12 Topics: Acetylglucosamine; Animals; Chemical Phenomena; Chemistry, Physical; Chickens; Chitinases; Enzyme Inhibitors; Fermentation; Insecticides; Spectrophotometry; Streptomyces; Trisaccharides	1987
Search for microbial insect growth regulators. II. Allosamidin, a novel insect chitinase inhibitor. The Journal of antibiotics, 1987, Volume: 40, Issue:3 Topics: Acetylglucosamine; Animals; Bombyx; Chitinases; Fermentation; Glucosamine; Insecta; Insecticides; Streptomyces; Trisaccharides	1987
Stereochemistry of chitin hydrolysis by a plant chitinase/lysozyme and X-ray structure of a complex with allosamidin: evidence for substrate assisted catalysis. Biochemistry, 1995, Dec-05, Volume: 34, Issue:48 Topics: Acetylglucosamine; Carbohydrate Sequence; Catalysis; Chitin; Chitinases; Crystallography, X-Ray; Glycoside Hydrolases; Hydrolysis; Molecular Sequence Data; Muramidase; Plant Proteins; Plants; Stereoisomerism; Substrate Specificity; Trisaccharides	1995
Chitinase activity in human serum and leukocytes. Infection and immunity, 1995, Volume: 63, Issue:12 Topics: Acetylglucosamine; Adult; Chitin; Chitinases; Electrophoresis, Polyacrylamide Gel; Female; Humans; Leukocytes; Male; Molecular Weight; Muramidase; Trisaccharides	1995
Synthesis of "Nod"-like chitin oligosaccharides by the Xenopus developmental protein DG42. Proceedings of the National Academy of Sciences of the United States of America, 1995, Apr-11, Volume: 92, Issue:8 Topics: Acetylglucosamine; Animals; Bacterial Proteins; Base Sequence; Chitin; Chitin Synthase; Chitinases; Glycosyltransferases; Membrane Proteins; Molecular Sequence Data; N-Acetylglucosaminyltransferases; Oligosaccharides; Proteins; Recombinant Proteins; Trisaccharides; Xenopus; Xenopus Proteins	1995
Biosynthetic studies of allosamidin. 2. Isolation of didemethylallosamidin, and conversion experiments of 14C-labeled demethylallosamidin, didemethylallosamidin and their related compounds. The Journal of antibiotics, 1993, Volume: 46, Issue:10 Topics: Acetylglucosamine; Carbohydrate Sequence; Chitinases; Chromatography, High Pressure Liquid; Insecticides; Molecular Sequence Data; Streptomyces; Trisaccharides	1993
Characteristics of an exochitinase from Streptomyces olivaceoviridis, its corresponding gene, putative protein domains and relationship to other chitinases. European journal of biochemistry, 1993, Jun-15, Volume: 214, Issue:3 Topics: Acetylglucosamine; Amino Acid Sequence; Base Sequence; Chitinases; Cloning, Molecular; Genes, Bacterial; Molecular Sequence Data; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Streptomyces; Trisaccharides	1993
Chitinolytic activities in Heligmosomoides polygyrus and their role in egg hatching. Molecular and biochemical parasitology, 1993, Volume: 58, Issue:2 Topics: Acetylglucosamine; Animals; Carbohydrate Sequence; Chitin; Chitinases; Egg Shell; Female; Histocytochemistry; Male; Molecular Sequence Data; Nematospiroides dubius; Trisaccharides	1993
Transmission-blocking activity of a chitinase inhibitor and activation of malarial parasite chitinase by mosquito protease. Proceedings of the National Academy of Sciences of the United States of America, 1993, May-01, Volume: 90, Issue:9 Topics: Acetylglucosamine; Aedes; Animals; Anopheles; Chickens; Chitinases; Endopeptidases; Enzyme Activation; Insecticides; Kinetics; Plasmodium falciparum; Plasmodium gallinaceum; Streptomyces griseus; Trisaccharides	1993
Inhibition of chitinolytic activities from tree species and associated fungi. Phytochemistry, 1996, Volume: 41, Issue:1 Topics: Acetylglucosamine; Carbohydrate Sequence; Chitinases; Enzyme Inhibitors; Eucalyptus; Fungi; Kinetics; Molecular Sequence Data; Oligosaccharides; Oximes; Phenylcarbamates; Plants, Medicinal; Species Specificity; Substrate Specificity; Trees; Trisaccharides	1996
The effect of chitinase inhibitors, cyclo(Arg-Pro) against cell separation of Saccharomyces cerevisiae and the morphological change of Candida albicans. The Journal of antibiotics, 1996, Volume: 49, Issue:8 Topics: Acetylglucosamine; Candida albicans; Chitinases; Enzyme Inhibitors; Peptides, Cyclic; Saccharomyces cerevisiae; Trisaccharides	1996
Identification and partial characterization of three chitinase forms in Entamoeba invadens with emphasis on their inhibition by allosamidin. Antonie van Leeuwenhoek, 1996, Volume: 70, Issue:1 Topics: Acetylglucosamine; Animals; Chitin; Chitinases; Chromatography, Gel; Chromatography, Ion Exchange; Durapatite; Entamoeba; Enzyme Inhibitors; Glycosides; Hymecromone; Isoenzymes; Molecular Weight; Trisaccharides	1996
Synthesis of allosamidin analogues. Carbohydrate research, 1996, Nov-20, Volume: 294 Topics: Acetylglucosamine; Animals; Carbohydrate Conformation; Carbohydrate Sequence; Chitinases; Enzyme Inhibitors; Insecta; Insecticides; Larva; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Structure-Activity Relationship; Trisaccharides	1996
Effect of demethylation on the chitinase inhibitory activity of allosamidin. Archives of insect biochemistry and physiology, 1997, Volume: 36, Issue:3 Topics: Acetylglucosamine; Animals; Artemia; Carbohydrate Sequence; Chironomidae; Chitinases; Enzyme Inhibitors; Kinetics; Methylation; Molecular Sequence Data; Serratia marcescens; Structure-Activity Relationship; Trisaccharides	1997
A novel role for the peritrophic matrix in protecting Leishmania from the hydrolytic activities of the sand fly midgut. Parasitology, 1997, Volume: 115 ( Pt 4) Topics: Acetylglucosamine; Animals; Chitinases; Digestive System; Eating; Hydrolysis; Insect Vectors; Leishmania major; Phlebotomus; Trisaccharides; Trypsin	1997
Substrate assistance in the mechanism of family 18 chitinases: theoretical studies of potential intermediates and inhibitors. Journal of molecular biology, 1998, Jul-31, Volume: 280, Issue:5 Topics: Acetylglucosamine; Binding Sites; Chitinases; Enzyme Inhibitors; Hydrolysis; Models, Molecular; Models, Theoretical; Protein Conformation; Substrate Specificity; Trisaccharides	1998
Involvement of chitinases of Bacillus thuringiensis during pathogenesis in insects. Microbiology (Reading, England), 1998, Volume: 144 ( Pt 8) Topics: Acetylglucosamine; Animals; Bacillus thuringiensis; Chironomidae; Chitinases; Larva; Pest Control, Biological; Spodoptera; Trisaccharides	1998
Allosamidin inhibits the fragmentation of Acremonium chrysogenum but does not influence the cephalosporin-C production of the fungus. FEMS microbiology letters, 1998, Jul-15, Volume: 164, Issue:2 Topics: Acetylglucosamine; Acremonium; Cephalosporins; Chitinases; Enzyme Inhibitors; Trisaccharides	1998
Preparation of biotinylated allosamidins with strong chitinase inhibitory activities. Bioorganic & medicinal chemistry letters, 1998, Nov-03, Volume: 8, Issue:21 Topics: Acetylglucosamine; Biosensing Techniques; Biotin; Chitinases; Enzyme Inhibitors; Trichoderma; Trisaccharides	1998
Distribution of chitinase in guinea pig tissues and increases in levels of this enzyme after systemic infection with Aspergillus fumigatus. Microbiology (Reading, England), 1999, Volume: 145 ( Pt 1) Topics: Acetylglucosamine; Animals; Aspergillosis; Aspergillus fumigatus; beta-N-Acetylhexosaminidases; Brain; Chitinases; Chromatography, Gel; Concanavalin A; Guinea Pigs; Hymecromone; Kidney; Liver; Lung; Molecular Weight; Myocardium; Oligosaccharides; Organ Specificity; Spleen; Time Factors; Trisaccharides	1999
The chitinase PfCHT1 from the human malaria parasite Plasmodium falciparum lacks proenzyme and chitin-binding domains and displays unique substrate preferences. Proceedings of the National Academy of Sciences of the United States of America, 1999, Nov-23, Volume: 96, Issue:24 Topics: Acetylglucosamine; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Chitin; Chitinases; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Gene Expression; Genes, Protozoan; Humans; Hydrogen-Ion Concentration; Malaria; Models, Molecular; Molecular Sequence Data; Plasmodium falciparum; Protein Conformation; Protozoan Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Trisaccharides	1999
Family 19 chitinases of Streptomyces species: characterization and distribution. Microbiology (Reading, England), 1999, Volume: 145 ( Pt 12) Topics: Acetylglucosamine; Amino Acid Sequence; Antifungal Agents; Blotting, Southern; Chitinases; Enzyme Inhibitors; Escherichia coli; Fungi; Gene Amplification; Molecular Sequence Data; Phylogeny; Plant Proteins; Polymerase Chain Reaction; Sequence Analysis, DNA; Streptomyces; Trisaccharides	1999
The X-ray structure of a chitinase from the pathogenic fungus Coccidioides immitis. Protein science : a publication of the Protein Society, 2000, Volume: 9, Issue:3 Topics: Acetylglucosamine; Amino Acid Sequence; Binding Sites; Chitinases; Coccidioides; Crystallography, X-Ray; Enzyme Inhibitors; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Trisaccharides	2000
Production and characterization of a thermostable chitinase from a new alkalophilic Bacillus sp. BG-11. Journal of applied microbiology, 2000, Volume: 88, Issue:5 Topics: Acetylglucosamine; Bacillus; Chitin; Chitinases; Chitosan; Endopeptidases; Enzyme Stability; Enzymes, Immobilized; Fermentation; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Weight; Temperature; Trisaccharides	2000
Chitin oligosaccharides as candidate patterning agents in zebrafish embryogenesis. The International journal of developmental biology, 2000, Volume: 44, Issue:2 Topics: Acetylglucosamine; Animals; Body Patterning; Chitin; Chitinases; Chromatography, High Pressure Liquid; Embryo, Nonmammalian; Hyaluronic Acid; In Situ Hybridization; Oligosaccharides; Time Factors; Trisaccharides; Zebrafish	2000
Enzyme kinetics of hevamine, a chitinase from the rubber tree Hevea brasiliensis. FEBS letters, 2000, Jul-28, Volume: 478, Issue:1-2 Topics: Acetylglucosamine; Binding, Competitive; Chitinases; Chromatography, High Pressure Liquid; Coloring Agents; Euphorbiaceae; Kinetics; Muramidase; Oligosaccharides; Oxidation-Reduction; Plant Proteins; Thermodynamics; Trisaccharides	2000
Biosynthetic studies on the cyclopentane ring formation of allosamizoline, an aminocyclitol component of the chitinase inhibitor allosamidin. The Journal of organic chemistry, 2001, May-18, Volume: 66, Issue:10 Topics: Acetylglucosamine; Chitinases; Deuterium; Enzyme Inhibitors; Glucosamine; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism; Streptomyces; Trisaccharides	2001
Growth of chitinolytic dune soil beta-subclass Proteobacteria in response to invading fungal hyphae. Applied and environmental microbiology, 2001, Volume: 67, Issue:8 Topics: Acetylglucosamine; Betaproteobacteria; Chitin; Chitinases; Colony Count, Microbial; Culture Media; Fungi; Molecular Sequence Data; Soil Microbiology; Trisaccharides	2001
Structural insights into the catalytic mechanism of a family 18 exo-chitinase. Proceedings of the National Academy of Sciences of the United States of America, 2001, Jul-31, Volume: 98, Issue:16 Topics: Acetylglucosamine; Catalysis; Chitinases; Crystallography, X-Ray; Hydrogen Bonding; Hydrolysis; Models, Molecular; Mutagenesis, Site-Directed; Plant Proteins; Protein Conformation; Substrate Specificity; Trisaccharides	2001
The structure of an allosamidin complex with the Coccidioides immitis chitinase defines a role for a second acid residue in substrate-assisted mechanism. Journal of molecular biology, 2002, Jul-05, Volume: 320, Issue:2 Topics: Acetylglucosamine; Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Chitinases; Coccidioides; Crystallography, X-Ray; Glutamic Acid; Glycoside Hydrolases; Kinetics; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Binding; Trisaccharides	2002
[Studies on allosamidin and aflastatin, novel inhibitors of important metabolic pathways, from microorganisms]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:3 Topics: Acetylglucosamine; Aflatoxins; Anti-Bacterial Agents; Enzyme Inhibitors; Pyrrolidinones; Trisaccharides	2002
Solution-state conformational study of the hevamine inhibitor allosamidin and six potential inhibitor analogues by NMR spectroscopy and molecular modeling. The Journal of organic chemistry, 2002, Sep-06, Volume: 67, Issue:18 Topics: Acetylglucosamine; Algorithms; Chitinases; Crystallography, X-Ray; Enzyme Inhibitors; Hevea; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Muramidase; Oligosaccharides; Plant Proteins; Solvents; Stereoisomerism; Structure-Activity Relationship; Trisaccharides	2002
Cloning and functional expression of a fat body-specific chitinase cDNA from the tsetse fly, Glossina morsitans morsitans. Insect biochemistry and molecular biology, 2002, Volume: 32, Issue:9 Topics: Acetylglucosamine; Amino Acid Sequence; Animals; Base Sequence; Chitinases; Cloning, Molecular; DNA, Complementary; Fat Body; Gene Expression; Hydrogen-Ion Concentration; Immunoblotting; Molecular Sequence Data; RNA, Messenger; Sequence Analysis, DNA; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Trisaccharides; Tsetse Flies	2002
The cyclic dipeptide CI-4 [cyclo-(l-Arg-d-Pro)] inhibits family 18 chitinases by structural mimicry of a reaction intermediate. The Biochemical journal, 2002, Nov-15, Volume: 368, Issue:Pt 1 Topics: Acetylglucosamine; Binding Sites; Chitinases; Molecular Conformation; Molecular Mimicry; Peptides, Cyclic; Plant Proteins; Protein Conformation; Protein Engineering; Serratia marcescens; Trisaccharides; X-Ray Diffraction	2002
NMR spectroscopic and theoretical study of the complexation of the inhibitor allosamidin in the binding pocket of the plant chitinase hevamine. Journal of molecular modeling, 2002, Volume: 8, Issue:8 Topics: Acetylglucosamine; Binding Sites; Chitinases; Enzyme Inhibitors; Hevea; Hydrogen Bonding; Insecticides; Macromolecular Substances; Models, Molecular; Models, Theoretical; Muramidase; Nuclear Magnetic Resonance, Biomolecular; Plant Proteins; Trisaccharides; Tryptophan; Tyrosine	2002
De novo purification scheme and crystallization conditions yield high-resolution structures of chitinase A and its complex with the inhibitor allosamidin. Acta crystallographica. Section D, Biological crystallography, 2003, Volume: 59, Issue:Pt 2 Topics: Acetylglucosamine; Amino Acids; Binding Sites; Chitinases; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors; Escherichia coli; Models, Molecular; Protein Conformation; Trisaccharides	2003
Purification and characterization of a new hyperthermostable, allosamidin-insensitive and denaturation-resistant chitinase from the hyperthermophilic archaeon Thermococcus chitonophagus. Extremophiles : life under extreme conditions, 2003, Volume: 7, Issue:1 Topics: Acetylglucosamine; Amino Acid Sequence; Cellulose; Chitin; Chitinases; Enzyme Inhibitors; Enzyme Stability; Guanidine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Molecular Weight; Protein Denaturation; Substrate Specificity; Thermococcus; Trisaccharides	2003
Crystal structures of allosamidin derivatives in complex with human macrophage chitinase. The Journal of biological chemistry, 2003, May-30, Volume: 278, Issue:22 Topics: Acetylglucosamine; Amino Acid Sequence; Chitinases; Crystallography, X-Ray; Humans; Macrophages; Models, Molecular; Molecular Sequence Data; Protein Conformation; Sequence Homology, Amino Acid; Trisaccharides	2003
Stereoselective synthesis of 2-amino-2-deoxysugars: N-alkyl-D-allosamines. Organic & biomolecular chemistry, 2003, May-21, Volume: 1, Issue:10 Topics: Acetylglucosamine; Amino Sugars; Chitinases; Deoxy Sugars; Glucosamine; Glucosides; Oxidation-Reduction; Stereoisomerism; Trisaccharides	2003
Nucleotide sequences of genes encoding allosamidin-sensitive and -insensitive chitinases produced by allosamidin-producing Streptomyces. Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:9 Topics: Acetylglucosamine; Amino Acid Sequence; Base Sequence; Chitinases; Cloning, Molecular; Enzyme Inhibitors; Isoenzymes; Molecular Sequence Data; Recombinant Proteins; Sequence Alignment; Streptomyces; Trisaccharides	2003
Structure of the D142N mutant of the family 18 chitinase ChiB from Serratia marcescens and its complex with allosamidin. Biochimica et biophysica acta, 2004, Jan-14, Volume: 1696, Issue:1 Topics: Acetylglucosamine; Binding, Competitive; Catalysis; Chitinases; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Serratia marcescens; Trisaccharides	2004
Development of a genetic system in chitinase-producing streptomyces and the application of an allosamidin-insensitive chitinase gene to homologous overexpression. Molecular biotechnology, 2004, Volume: 26, Issue:3 Topics: Acetylglucosamine; Bacterial Proteins; Chitinases; DNA Methylation; Drug Resistance, Bacterial; Enzyme Inhibitors; Escherichia coli; Gene Expression Regulation, Bacterial; Genetic Vectors; Methyltransferases; Promoter Regions, Genetic; Recombinant Proteins; Sequence Homology; Streptomyces; Transfection; Trisaccharides	2004
Kinetic analysis of a chitinase from red sea bream, Pagrus major. Bioscience, biotechnology, and biochemistry, 2004, Volume: 68, Issue:6 Topics: Acetylglucosamine; Animals; Binding, Competitive; Chitin; Chitinases; Kinetics; Oligosaccharides; Sea Bream; Trisaccharides	2004
Molecular cloning and functional characterization of mouse chitotriosidase. Gene, 2005, Aug-29, Volume: 357, Issue:1 Topics: Acetylglucosamine; Amino Acid Sequence; Animals; Chitin; Chitinases; Chromosomes; Cloning, Molecular; Enzyme Activation; Enzyme Inhibitors; Hexosaminidases; Mice; Molecular Sequence Data; Multigene Family; Open Reading Frames; Organ Specificity; Protein Binding; Recombinant Proteins; Sequence Homology, Amino Acid; Trisaccharides	2005
Molecular cloning, characterization, and expression studies of a novel chitinase gene (ech30) from the mycoparasite Trichoderma atroviride strain P1. FEMS microbiology letters, 2006, Volume: 256, Issue:2 Topics: 5' Untranslated Regions; Acetylglucosamine; Amino Acid Sequence; Botrytis; Chitin; Chitinases; Cloning, Molecular; Conserved Sequence; DNA, Fungal; Enzyme Inhibitors; Escherichia coli; Gene Expression Regulation, Fungal; Introns; Molecular Sequence Data; Molecular Weight; Phylogeny; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Fungal; RNA, Messenger; Sequence Alignment; Sequence Analysis, DNA; Trichoderma; Trisaccharides	2006
Differential aphicidal effects of chitinase inhibitors on the polyphagous homopteran Myzus persicae (Sulzer). Pest management science, 2006, Volume: 62, Issue:12 Topics: Acetylglucosamine; Animals; Aphids; Chitinases; Disulfides; Female; Insecticides; Trisaccharides; Tyrosine	2006
Chitinase inhibitor allosamidin is a signal molecule for chitinase production in its producing Streptomyces I. Analysis of the chitinase whose production is promoted by allosamidin and growth accelerating activity of allosamidin. The Journal of antibiotics, 2006, Volume: 59, Issue:7 Topics: Acetylglucosamine; Chitin; Chitinases; Molecular Structure; Signal Transduction; Streptomyces; Trisaccharides	2006
Chitinase inhibitor allosamidin is a signal molecule for chitinase production in its producing Streptomyces II. Mechanism for regulation of chitinase production by allosamidin through a two-component regulatory system. The Journal of antibiotics, 2006, Volume: 59, Issue:7 Topics: Acetylglucosamine; Chitin; Chitinases; Disaccharides; Gene Expression Regulation, Enzymologic; Gene Silencing; Molecular Structure; Signal Transduction; Streptomyces; Trisaccharides	2006
Structure of Saccharomyces cerevisiae chitinase 1 and screening-based discovery of potent inhibitors. Chemistry & biology, 2007, Volume: 14, Issue:5 Topics: Acetazolamide; Acetylglucosamine; Amino Acid Sequence; Binding Sites; Chitinases; Cloning, Molecular; Conserved Sequence; Crystallography, X-Ray; Enzyme Inhibitors; Fluorescent Dyes; Glycosides; Hydrogen-Ion Concentration; Hymecromone; Kinetin; Models, Molecular; Molecular Sequence Data; Plants; Purines; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Structure-Activity Relationship; Trisaccharides	2007
Thermodynamic analysis of allosamidin binding to a family 18 chitinase. Biochemistry, 2007, Oct-30, Volume: 46, Issue:43 Topics: Acetylglucosamine; Chitinases; Hydrogen-Ion Concentration; Lectins; Models, Molecular; Protein Binding; Serratia marcescens; Thermodynamics; Trisaccharides	2007
Chitinase inhibitor allosamidin promotes chitinase production of Streptomyces generally. International journal of biological macromolecules, 2008, Jul-01, Volume: 43, Issue:1 Topics: Acetylglucosamine; Chitinases; DNA, Bacterial; Enzyme Inhibitors; Molecular Sequence Data; Phylogeny; Promoter Regions, Genetic; Soil Microbiology; Streptomyces; Trisaccharides	2008
Effect of chitinase inhibitors on endotoxin-induced uveitis (EIU) in rabbits. Pharmacological research, 2008, Volume: 57, Issue:3 Topics: Acetylglucosamine; Animals; Anti-Inflammatory Agents; Caffeine; Chitinases; Dexamethasone; Endotoxins; Enzyme Inhibitors; Escherichia coli; Kinetics; Lipopolysaccharides; Male; Phosphodiesterase Inhibitors; Rabbits; Tears; Trisaccharides; Uveitis	2008
Analysis of a three-dimensional structure of human acidic mammalian chitinase obtained by homology modeling and ligand binding studies. Journal of molecular modeling, 2009, Volume: 15, Issue:5 Topics: Acetylglucosamine; Amino Acid Sequence; Binding Sites; Chitin; Chitinases; Humans; Hydrogen Bonding; Ligands; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Sequence Alignment; Software; Static Electricity; Structural Homology, Protein; Thermodynamics; Trisaccharides	2009
Triad of polar residues implicated in pH specificity of acidic mammalian chitinase. Protein science : a publication of the Protein Society, 2009, Volume: 18, Issue:3 Topics: Acetylglucosamine; Amino Acid Sequence; Animals; Asthma; Catalytic Domain; Chitinases; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Humans; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Protein Conformation; Substrate Specificity; Trisaccharides	2009
Chitinase gene expression in response to environmental stresses in Arabidopsis thaliana: chitinase inhibitor allosamidin enhances stress tolerance. Bioscience, biotechnology, and biochemistry, 2009, Volume: 73, Issue:5 Topics: Acetylglucosamine; Arabidopsis; Chitinases; Enzyme Inhibitors; Gene Expression Regulation, Plant; Reverse Transcriptase Polymerase Chain Reaction; Stress, Physiological; Trisaccharides	2009
Enzymatic characterization of the Plasmodium vivax chitinase, a potential malaria transmission-blocking target. Parasitology international, 2009, Volume: 58, Issue:3 Topics: Acetylglucosamine; Animals; Chitin; Chitinases; Enzyme Inhibitors; Enzyme Precursors; Humans; Hydrogen-Ion Concentration; Hymecromone; Malaria; Plasmodium vivax; Protozoan Proteins; Recombinant Proteins; Temperature; Trisaccharides	2009
Demethylallosamidin, a chitinase inhibitor, suppresses airway inflammation and hyperresponsiveness. Biochemical and biophysical research communications, 2009, Dec-04, Volume: 390, Issue:1 Topics: Acetylglucosamine; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Chemokine CCL11; Chitinases; Cyclooxygenase 2 Inhibitors; Down-Regulation; Interleukin-13; Lung; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Pneumonia; Trisaccharides	2009
Transglycosylation reaction catalyzed by a class V chitinase from cycad, Cycas revoluta: a study involving site-directed mutagenesis, HPLC, and real-time ESI-MS. Biochimica et biophysica acta, 2010, Volume: 1804, Issue:4 Topics: Acetylglucosamine; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Catalytic Domain; Chitinases; Chromatography, High Pressure Liquid; Cycas; DNA Primers; DNA, Plant; Enzyme Inhibitors; Glycosylation; Kinetics; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligosaccharides; Recombinant Proteins; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Trisaccharides	2010
The roles of three Serratia marcescens chitinases in chitin conversion are reflected in different thermodynamic signatures of allosamidin binding. The journal of physical chemistry. B, 2010, May-13, Volume: 114, Issue:18 Topics: Acetylglucosamine; Catalytic Domain; Chitin; Chitinases; Crystallography, X-Ray; Enzyme Inhibitors; Protein Structure, Tertiary; Serratia marcescens; Thermodynamics; Trisaccharides	2010
Preparation of allosamidin and demethylallosamidin photoaffinity probes and analysis of allosamidin-binding proteins in asthmatic mice. Bioorganic & medicinal chemistry, 2011, May-15, Volume: 19, Issue:10 Topics: Acetylglucosamine; Animals; Anti-Asthmatic Agents; Asthma; beta-N-Acetylhexosaminidases; Bronchoalveolar Lavage Fluid; Chitinases; Enzyme Inhibitors; Lectins; Male; Mice; Protein Binding; Recombinant Proteins; Streptomyces; Trisaccharides	2011
A modeling study for structure features of β-N-acetyl-D-hexosaminidase from Ostrinia furnacalis and its novel inhibitor allosamidin: species selectivity and multi-target characteristics. Chemical biology & drug design, 2012, Volume: 79, Issue:4 Topics: Acetylglucosamine; Amino Acid Sequence; Animals; beta-N-Acetylhexosaminidases; Binding Sites; Chitinases; Humans; Insecticides; Lepidoptera; Models, Molecular; Molecular Sequence Data; Protein Binding; Sequence Alignment; Trisaccharides	2012
Purification and characterisation of a 31-kDa chitinase from the Myzus Persicae aphid: a target for hemiptera biocontrol. Applied biochemistry and biotechnology, 2012, Volume: 166, Issue:5 Topics: Acetylglucosamine; Animals; Aphids; Chitinases; Disulfides; Enzyme Inhibitors; Molecular Weight; Pest Control, Biological; Trisaccharides; Tyrosine	2012
Chitinase inhibition promotes atherosclerosis in hyperlipidemic mice. The American journal of pathology, 2013, Volume: 183, Issue:1 Topics: Acetylglucosamine; Animals; Atherosclerosis; Biomarkers; Cell Line; Chitinases; Cytokines; Enzyme Inhibitors; Macrophages; Male; Mice; Mice, Knockout; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Trisaccharides	2013
High production of cold-tolerant chitinases on shrimp wastes in bench-top bioreactor by the Antarctic fungus Lecanicillium muscarium CCFEE 5003: bioprocess optimization and characterization of two main enzymes. Enzyme and microbial technology, 2013, Oct-10, Volume: 53, Issue:5 Topics: Acetylglucosamine; Animals; Antarctic Regions; Bioengineering; Bioreactors; Brachyura; Chitin; Chitinases; Cold Temperature; Enzyme Inhibitors; Fermentation; Hydrogen-Ion Concentration; Hypocreales; Molecular Weight; Penaeidae; Seawater; Trisaccharides; Waste Products	2013
Identification of the allosamidin-releasing factor in allosamidin-producing Streptomyces. The Journal of antibiotics, 2014, Volume: 67, Issue:2 Topics: Acetylglucosamine; Chitin; Chitinases; Streptomyces; Trisaccharides	2014
Targeting AMCase reduces esophageal eosinophilic inflammation and remodeling in a mouse model of egg induced eosinophilic esophagitis. International immunopharmacology, 2014, Volume: 18, Issue:1 Topics: Acetylglucosamine; Allergens; Animals; Cells, Cultured; Chemokine CCL11; Chitinases; Disease Models, Animal; Eggs; Enzyme Inhibitors; Eosinophilic Esophagitis; Esophagus; Female; Fibrosis; Humans; Hyperplasia; Hypersensitivity, Immediate; Inflammation Mediators; Mice, Inbred BALB C; Molecular Targeted Therapy; Ovalbumin; Trisaccharides	2014
Crystal structures and inhibitor binding properties of plant class V chitinases: the cycad enzyme exhibits unique structural and functional features. The Plant journal : for cell and molecular biology, 2015, Volume: 82, Issue:1 Topics: Acetylglucosamine; Amino Acid Motifs; Amino Acid Sequence; Arabidopsis; Bacterial Proteins; Binding Sites; Chitin; Chitinases; Crystallography, X-Ray; Cycas; Enzyme Inhibitors; Evolution, Molecular; Glycosylation; Molecular Sequence Data; Nicotiana; Plant Proteins; Sequence Alignment; Serratia; Temperature; Trisaccharides	2015