alkenes has been researched along with salvianolic acid a in 106 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 82 (77.36) | 24.3611 |
| 2020's | 24 (22.64) | 2.80 |
| Authors | Studies |
|---|---|
| Li, H; Liu, W; Wang, J; Wang, S; Xie, Y; Yang, Q; Zhou, X | 1 |
| Chen, SL; Li, XW; Li, Y; Luo, HM; Niu, YY; Sun, C | 1 |
| Guan, SH; Guo, DA; Jiang, BH; Liu, X; Song, XY; Wu, WY; Xie, FB; Yang, M; Yue, QX | 1 |
| Hu, ZB; Wang, ZT; Yang, L; Zhang, JJ; Zhao, SJ | 1 |
| Chen, T; Mo, H; Qu, H; Wang, L; Wang, Y; Zeng, S | 1 |
| Huang, J; Li, GY; Liu, XH; Sun, SQ; Wang, JH; Xu, CH; Zhang, K; Zhang, ZC; Zhou, Q; Zhu, Y | 1 |
| De Bellis, L; Miceli, A; Negro, C | 1 |
| Alford, BL; Hügel, HM | 1 |
| Hao, GP; Li, YL; Miao, ZM; Shi, RJ; Xin, XM | 1 |
| Chen, JD; Chen, XH; He, Y; Shi, HB; Yang, ZJ | 1 |
| Gong, W; Wang, Y; Xiao, Y; Zhang, M | 1 |
| Cao, Y; Fan, ZK; Li, G; Lv, G; Mei, XF; Wang, YF; Wang, YS; Yu, DS; Zhang, YQ | 1 |
| Chen, SL; Li, CF; Luo, HM; Song, JY; Sun, C; Xu, J | 1 |
| Che, X; Fan, H; Li, Y; Liu, K; Tian, H; Xu, H | 1 |
| Dai, Z; Lin, R; Liu, J; Ma, S; Wang, G; Zhao, J | 1 |
| Gao, L; Liang, Y; Qiao, Z; Wang, T; Yang, D; Yu, B; Zhang, P | 1 |
| Fan, JY; Han, JY; Liu, YY; Mao, XW; Pan, CS; Tang, H; Yan, L; Zhang, SY; Zhou, CM | 1 |
| Chen, XY; Jia, XB; Liu, D; Sun, E; Yu, DH; Zhang, ZH | 1 |
| Kuai, BK; Qin, MJ; Wang, W; Xie, XM; Zhou, GJ; Zhou, TS | 1 |
| Chen, XY; Jia, XB; Liu, D; Sun, E; Zhang, ZH | 1 |
| Chen, Q; Chen, X; Li, D; Liu, Y; Pan, D; Wu, X; Xu, T; Zhu, S | 1 |
| Guo, ZX; Han, M; Huang, XF; Jin, YP; Li, SM; Li, W; Ma, XH; Sun, H; Yan, KJ; Yu, Y; Zhou, SP; Zhou, W; Zhu, YH | 1 |
| Chen, B; Du, G; Guo, J; Li, X; Qiang, G; Shi, L; Xuan, Q; Yang, H; Yang, X; Zhang, H; Zhang, L; Zhou, D; Zu, M | 1 |
| Geng, W; Gong, J; He, Y; Ju, A; Li, B; Li, D; Li, L; Lin, R; Liu, Y; Song, M; Wang, Y; Ye, Z; Zhou, D; Zhou, W | 1 |
| Guan, L; Li, ZY; Yao, WJ; Zhang, YL; Zhao, JY; Zhu, MX | 1 |
| Kang, J; Li, F; Li, M; Zhang, Y | 1 |
| Chen, J; Dong, X; Li, P; Lu, J; Song, HP; Zhou, P | 1 |
| Boye, A; Jiang, Y; Wang, J; Wu, C; Wu, J; Yang, X; Yang, Y | 1 |
| Chen, B; Du, G; Guo, J; Qiang, G; Shi, L; Yang, H; Yang, X; Zhang, H; Zhang, L; Zhao, Y; Zhou, D; Zu, M | 1 |
| Bergonzi, MC; Bilia, AR; Bonaccini, L; Karioti, A | 1 |
| An, C; Chen, Q; Jia, L; Li, Y; Wang, M; Wang, S; Yu, L; Zhen, F | 1 |
| Chai, Y; Chen, L; Hu, Z; Li, J; Lu, B; Lu, Y; Wu, H; Zhang, J; Zhang, L | 1 |
| Fu, X; Gu, T; Li, J; Zhao, R | 1 |
| Ju, A; Li, N; Lin, B; Liu, X; Si, Y; Tong, L; Wang, W; Xing, Y; Xu, J; Yue, H | 1 |
| Du, G; He, G; Song, J; Sun, L; Yang, S; Zhang, L; Zhang, W; Zhao, R | 1 |
| Han, X; Huang, J; Li, S; Liu, X; Miao, J; Sun, G; Sun, W; Tong, L | 1 |
| Chen, X; Guo, Y; Hu, Y; Qi, J; Yu, B | 1 |
| Huang, J; Liu, X; Miao, J; Sun, G; Sun, H; Sun, W; Tong, L; Xie, X; Xu, J | 1 |
| Cai, L; Chen, Y; Ding, ZT; Wang, YR; Xing, Y; Yin, TP; Yu, J | 1 |
| Ding, C; Gao, D; Li, Z; Lv, L; Shi, X; Tian, X; Yao, J; Zhang, N; Zhao, Y; Zhou, J; Zu, G | 1 |
| Guo, Y; Hua, L; Liu, Z; Qin, W; Yang, Y; Zheng, X | 1 |
| Du, GH; He, YY; Hou, BY; Ma, LL; Niu, ZR; Pang, XC; Song, JK; Wu, P; Yan, Y; Yang, XY; Zhang, L | 1 |
| Feng, JC; Hou, S; Liu, XP; Shen, PP; Sun, Y; Zhao, MM | 1 |
| Chen, C; Deng, K; Gao, Y; Liu, D; Liu, Y; Song, W; Wang, C; Wei, T; Yang, M; Zhang, L; Zhang, Y; Zheng, X | 1 |
| Barrajón-Catalán, E; Castillo, J; Herranz-López, M; Micol, V; Pérez-Sánchez, A | 1 |
| Huang, J; Li, D; Li, S; Miao, J; Sun, G; Sun, W; Tong, L; Xie, X | 1 |
| Deng, K; Ji, L; Liu, Y; Sun, G; Zhang, Y; Zheng, X; Zhong, Z; Zhou, J | 1 |
| Li, C; Lu, L; Shi, T; Wang, Q; Wang, W; Wang, Y; Zhang, Q; Zhang, Y | 1 |
| Jiang, H; Liu, HC; Liu, XQ; Wang, YH; Wei, CX; Zhang, X | 1 |
| Feng, B; Geng, S; He, Y; Ju, A; Li, D; Li, H; Wan, Y; Wei, H; Ye, Z; Zhang, Y; Zhou, D; Zhuang, P | 1 |
| Huang, J; Li, D; Li, Y; Lu, T; Nie, W; Shao, Y; Tong, L; Zhang, W; Zhu, Y | 1 |
| Geng, Y; Han, B; Shen, L; Wang, J; Wang, M; Wang, Z | 1 |
| Chen, D; Li, M; Wu, T; Zhang, J; Zhang, X | 1 |
| Bao, XY; Chu, MP; Thapa, S; Wang, Y; Yu, LJ; Zhang, KJ; Zheng, Q; Zhu, JZ | 1 |
| Chen, R; Cui, L; Dong, L; He, T; Li, P; Li, Y; Shen, Z; Wen, Y; Zhang, C; Zhang, X; Zhang, Y; Zhao, J; Zheng, X; Zhu, X | 2 |
| Dai, JD; Huang, RX; Jiang, QL; Li, YJ; Liu, LH; Mao, YW; Zhai, WW | 1 |
| Chen, WJ; Liang, WY; Mao, X; Shao, YY; Wu, LF; Yang, GH; Zhang, LZ; Zhang, XX; Zhu, D | 1 |
| Dong, ZB; Feng, L; Han, XJ; Jia, XB; Li, C; Liu, D | 1 |
| Hou, XM; Ju, AC; Ye, ZL; Yue, HS; Zhang, L | 1 |
| Ju, AC; Ye, ZL; Yue, HS; Zhang, L | 1 |
| Chen, J; Chen, QY; Jiao, DM; Tang, XL; Yan, L; Zhu, L | 1 |
| Gao, H; Jin, X; Song, Y; Sun, J; Zhang, S; Zhang, Y | 1 |
| Li, D; Li, S; Tong, L; Xie, X; Yu, Z; Zhao, Y | 1 |
| Ding, K; Dong, J; Jia, Y; Liang, Z; Liu, S; Ma, P; Pei, T; Ru, M | 1 |
| Bräm, S; Esslinger, N; Grubelnik, A; Josuran, R; Meier, N; Opitz, SEW; Peter, S; Trifan, A; Wolfram, E | 1 |
| Bai, J; Cheng, L; Ding, Y; Gao, K; He, L; Jia, Y; Li, L; Liu, M; Liu, W; Song, Y; Wang, F; Wen, A; Yao, M; Zhang, Y; Zhao, J | 1 |
| Habtemariam, S | 1 |
| Che, D; He, H; He, L; Hou, Y; Lin, Y; Sun, M; Sun, W; Wang, C; Yang, L; Zhang, T | 1 |
| Chen, M; Chu, Y; Huang, L; Ju, A; Li, D; Li, W; Li, Y; Liu, C; Polachi, N; Tian, M; Wang, X; Wang, Y; Zhang, Y; Zhou, D; Zhou, S | 1 |
| Choi, JS; Jung, HA; Kim, JA; Paudel, P; Seong, SH; Yu, T | 1 |
| Dai, J; Wang, J; Yu, J; Zhai, W | 1 |
| Chang, X; Chen, QF; Fan, JY; Han, JY; Hu, BH; Li, Q; Liu, YY; Pan, CS; Yan, L | 1 |
| Gao, H; Qu, X; Song, Y; Tao, L; Zhai, J; Zhang, S; Zhang, Y | 1 |
| Li, Y; Yang, D; Zhu, C | 1 |
| Gao, W; Li, P; Li, XS; Liu, K; Liu, XG; Wang, HY; Wu, QW; Yang, H; Zhang, JW | 1 |
| Chen, J; Hu, CY; Jiao, KL; Li, Y; Li, Z; Liu, J; Liu, Y; Teng, MY; Wu, MX; Yue, J; Zhen, J; Zhou, M | 1 |
| Anand, P; Gandhi, M; Jadhav, M; Padwad, Y; Purohit, R; Rawat, K; Shard, A; Sinha, AK | 1 |
| Guo, X; Mo, X; Morsi, Y; You, Z; Zhang, H; Zhu, J; Zhu, T | 1 |
| Cao, W; Duan, J; Guo, J; Leng, J; Li, J; Shang, E; Shen, Z; Wang, N; Wang, Y; Xu, X; Zhu, Z; Zou, N | 1 |
| Bo, P; Chen, SW; Hang, C; Wang, KK; Yan, HS | 1 |
| Lyu, J; Wang, L; Wang, Z; Xie, Y | 1 |
| Cao, P; Han, J; Wang, G; Wei, X | 1 |
| Du, G; Du, L; Fang, L; Qiang, G; Song, J; Wang, S; Yang, X; Zhang, L | 1 |
| Chen, J; Chen, M; Ma, Q; Yang, Q; Yu, C; Zhang, L; Zhou, W | 1 |
| Duan, JA; Gu, W; Guo, J; Guo, S; Qian, D; Su, S; Sun, C; Yu, L; Zhu, Y | 1 |
| Jin, HY; Li, YL; Liu, LN; Ma, SC; Wang, Y; Yue, HS | 1 |
| Chen, CP; Chen, YP; Feng, L; Jia, XB; Qi, CL; Shi, XH; Wang, GY; Yang, B | 1 |
| Deng, C; Huang, F; Kai, G; Lu, S; Ma, X; Wang, Y; Zhao, L | 1 |
| Han, R; Li, B; Wu, Q; Xiu, R; Yuan, X; Zhang, H | 1 |
| Feng, J; Hao, Y; Huang, G; Liang, Z; Ma, D; Miao, J; Wang, X; Xin, M | 1 |
| Bunzel, M; Félix, LM; Martins-Gomes, C; Nunes, FM; Santos, JA; Schäfer, J; Silva, AM; Taghouti, M | 1 |
| Chen, M; Li, H; Tan, R; Wang, Z; Zhang, J; Zhao, S; Zheng, X | 1 |
| Duan, H; Li, S; Liu, J; Tang, C; Wang, Y; Ye, Y; Zhao, G; Zhu, N | 1 |
| Alolga, RN; Chen, Y; Fan, H; Fan, Y; Li, LZ; Li, P; Li, W; Lu, X; Ma, G; Qi, LW; Song, W; Tran, LP; Yin, X; Zhang, B; Zhou, W | 1 |
| Li, B; Pan, J; Qu, H; Xiong, D; Zhang, L | 1 |
| Dong, Z; Guo, C; Qiu, B; Xue, C; Yang, H | 1 |
| Cao, M; Chen, W; Jiang, W; Liu, Y; Meng, X; Peng, D; Xing, S; Zhang, W | 1 |
| Chen, HS; Ma, DC; Zhang, NN; Zhang, YN | 1 |
| Bai, H; He, L; Hu, S; Wang, C; Wang, J; Wang, N; Zhang, Y | 1 |
| Qu, T; Wang, XL; Wang, YH; Yang, RP | 1 |
| Fu, Y; Jiang, B; Wang, L; Xing, R; Yang, L | 1 |
| Liang, S; Liu, P; Sun, S; Yu, L; Zheng, Z | 1 |
| Chu, Y; Ju, A; Li, D; Li, W; Li, X; Li, Y; Wu, Y; Xie, Y; Zheng, D | 1 |
| Cao, XY; Hua, WP; Wang, DH; Wang, XZ; Yang, JX; Yang, QQ; Zhang, T; Zhu, XJ; Zou, HL | 1 |
| Chen, X; Chen, Y; Huang, ZF; Liu, YH; Qin, DY; Yi, JH | 1 |
7 review(s) available for alkenes and salvianolic acid a
| Article | Year |
|---|---|
[Salvia miltiorrhiza as medicinal model plant].
Topics: Abietanes; Alkenes; Chromosome Mapping; Ethnopharmacology; Genome, Plant; Medicine, Chinese Traditional; Plants, Medicinal; Polyphenols; Salvia miltiorrhiza; Transcriptome | 2013 |
Effects of Salvia miltiorrhiza on CNS Neuronal Injury and Degeneration: A Plausible Complementary Role of Tanshinones and Depsides.
Topics: Abietanes; Alkenes; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cyclooxygenase 2; Depsides; Humans; Medicine, Chinese Traditional; Nerve Degeneration; Nitric Oxide Synthase Type II; Polyphenols; Salvia miltiorrhiza | 2015 |
Salvianolic Acid Exerts Cardioprotection through Promoting Angiogenesis in Animal Models of Acute Myocardial Infarction: Preclinical Evidence.
Topics: Acute Disease; Alkenes; Angiogenesis Inducing Agents; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Female; Male; Myocardial Infarction; Polyphenols; Rats; Rats, Sprague-Dawley; Swine | 2017 |
[Research progress on salvianolic acids of Salvia miltiorrhiza].
Topics: Alkenes; Animals; Drug Therapy; Drugs, Chinese Herbal; Humans; Molecular Structure; Polyphenols; Salvia miltiorrhiza | 2016 |
Molecular Pharmacology of Rosmarinic and Salvianolic Acids: Potential Seeds for Alzheimer's and Vascular Dementia Drugs.
Topics: Alkenes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Differentiation; Cinnamates; Dementia, Vascular; Depsides; Disease Models, Animal; Gene Expression Regulation; Humans; Lactates; Neural Stem Cells; Neurons; Neuroprotective Agents; Nootropic Agents; Polyphenols; Rosmarinic Acid; Stroke; tau Proteins | 2018 |
Salvianolic Acids for Injection Combined with Conventional Treatment for Patients with Acute Cerebral Infarction: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Topics: Activities of Daily Living; Acute Disease; Alkenes; Brain Ischemia; Cerebral Infarction; Drugs, Chinese Herbal; Humans; Injections; Medicine, Chinese Traditional; Polyphenols; Stroke; Treatment Outcome | 2019 |
Chemical and pharmacological research on the polyphenol acids isolated from Danshen: A review of salvianolic acids.
Topics: Alkenes; Animals; Apoptosis; Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional; Polyphenols; Salvia miltiorrhiza | 2020 |
99 other study(ies) available for alkenes and salvianolic acid a
| Article | Year |
|---|---|
Effect of salvianolic acid B and paeonol on blood lipid metabolism and hemorrheology in myocardial ischemia rabbits induced by pituitruin.
Topics: Acetophenones; Alkenes; Animals; Creatine Kinase; Drug Therapy, Combination; Fibrinogen; Hemorheology; L-Lactate Dehydrogenase; Lipid Metabolism; Lipoproteins, HDL; Malondialdehyde; Myocardial Ischemia; Nitric Oxide; Pituitary Hormones, Posterior; Polyphenols; Rabbits | 2010 |
[Transcriptome characterization for Salvia miltiorrhiza using 454 GS FLX].
Topics: Abietanes; Alkenes; Cytochrome P-450 Enzyme System; Databases, Nucleic Acid; DNA, Plant; Expressed Sequence Tags; Gene Expression Profiling; Genes, Plant; High-Throughput Nucleotide Sequencing; Microsatellite Repeats; Plant Roots; Plants, Medicinal; Polyphenols; Salvia miltiorrhiza; Sequence Analysis, DNA; Transcriptome | 2010 |
Proteomic studies on protective effects of salvianolic acids, notoginsengnosides and combination of salvianolic acids and notoginsengnosides against cardiac ischemic-reperfusion injury.
Topics: Alkenes; Animals; Creatine Kinase; Disease Models, Animal; Drugs, Chinese Herbal; Electrophoresis, Gel, Two-Dimensional; Male; Medicine, Chinese Traditional; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Panax notoginseng; Plants, Medicinal; Polyphenols; Proteomics; Rats; Rats, Wistar; Salvia miltiorrhiza; Saponins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors | 2012 |
Determination and biosynthesis of multiple salvianolic acids in hairy roots of Salvia miltiorrhiza.
Topics: Acetates; Alkenes; Benzofurans; Cinnamates; Cyclopentanes; Depsides; Oxylipins; Phenylpropionates; Plant Growth Regulators; Plant Roots; Plants, Medicinal; Polyphenols; Rosmarinic Acid; Salvia miltiorrhiza; Yeasts | 2011 |
Direct analysis in real time mass spectrometry and multivariate data analysis: a novel approach to rapid identification of analytical markers for quality control of traditional Chinese medicine preparation.
Topics: Alkenes; Carbohydrates; Drugs, Chinese Herbal; Mass Spectrometry; Multivariate Analysis; Polyphenols; Principal Component Analysis; Quality Control; Reproducibility of Results; Salvia miltiorrhiza; Sensitivity and Specificity; Time Factors | 2012 |
Discrimination of different genuine Danshen and their extracts by Fourier transform infrared spectroscopy combined with two-dimensional correlation infrared spectroscopy.
Topics: Alkenes; Plant Extracts; Polyphenols; Salvia miltiorrhiza; Spectroscopy, Fourier Transform Infrared | 2012 |
Antioxidant activity of Buglossoides purpureocaerulea (L.) I.M. Johnst. extracts.
Topics: Alkenes; Antioxidants; Benzofurans; Biphenyl Compounds; Boraginaceae; Caffeic Acids; Cinnamates; Depsides; Free Radical Scavengers; Picrates; Plant Extracts; Polyphenols; Rosmarinic Acid | 2013 |
Total synthesis of (+)-pentamethylsalvianolic acid C.
Topics: Alkenes; Benzofurans; Copper; Drugs, Chinese Herbal; Methylation; Polyphenols; Salvia miltiorrhiza; Stereoisomerism | 2013 |
[Study on effective constituents extracted from fibrous roots of Salvia miltiorrhiza with degrading multi-enzymes from taishan Ganoderma lucidum].
Topics: Abietanes; Alkenes; Drugs, Chinese Herbal; Hydrogen-Ion Concentration; Plant Roots; Polyphenols; Reishi; Salvia miltiorrhiza; Temperature; Wood | 2013 |
Effects of salvianolic acid and notoginseng triterpenes on angiogenesis in EA-hy926 cells in vitro.
Topics: Alkenes; Cell Line, Tumor; Cell Proliferation; Coronary Stenosis; Drugs, Chinese Herbal; Endothelial Cells; Humans; Neovascularization, Pathologic; Panax notoginseng; Polyphenols; Triterpenes; Vascular Endothelial Growth Factor A | 2013 |
[Synergistic protective effects of salvianolic acids and Panax notoginseng saponins on cardiomyocytes with hypoxia-reoxygenation injury].
Topics: Alkenes; Animals; Apoptosis; Cell Hypoxia; Cell Line; Drug Synergism; Myocytes, Cardiac; Oxygen; Panax notoginseng; Polyphenols; Rats; Saponins | 2013 |
The protective effect of salvianolic acid B on blood-spinal cord barrier after compression spinal cord injury in rats.
Topics: Alkenes; Animals; Capillary Permeability; Cytokines; Heme Oxygenase-1; Locomotion; Male; Neuroprotective Agents; NF-kappa B; Occludin; Polyphenols; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Tumor Necrosis Factor-alpha; Water; Zonula Occludens-1 Protein | 2013 |
Metabolism of salvianolic acid A and antioxidant activities of its methylated metabolites.
Topics: Alkenes; Animals; Antioxidants; Bile; Biotransformation; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucuronides; Lipid Peroxidation; Male; Methylation; Polyphenols; Rats; Rats, Sprague-Dawley | 2014 |
A pair of new antioxidant phenolic acid stereoisomers isolated from danshen injection (lyophilized powder).
Topics: Alkenes; Antioxidants; Drugs, Chinese Herbal; Free Radical Scavengers; Hydroxybenzoates; Phenols; Polyphenols; Salvia miltiorrhiza; Stereoisomerism | 2014 |
SalA attenuates ischemia/reperfusion-induced endothelial barrier dysfunction via down-regulation of VLDL receptor expression.
Topics: Alkenes; Down-Regulation; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Polyphenols; Receptors, LDL; Reperfusion Injury; RNA, Messenger | 2014 |
Role of NADPH oxidase in total salvianolic acid injection attenuating ischemia-reperfusion impaired cerebral microcirculation and neurons: implication of AMPK/Akt/PKC.
Topics: Alkenes; AMP-Activated Protein Kinases; Animals; Apoptosis; Capillary Permeability; Cerebral Infarction; Drugs, Chinese Herbal; Infarction, Middle Cerebral Artery; Leukocytes; Lipid Peroxidation; Male; Microcirculation; Movement Disorders; NADPH Oxidases; Nerve Tissue Proteins; Neurons; Phosphorylation; Polyphenols; Protein Kinase C; Protein Transport; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction | 2014 |
[Study on preparation of salvianolic acid phospholipid compound].
Topics: Alkenes; Chemical Phenomena; Chemistry, Pharmaceutical; Glycine max; Intestinal Absorption; Phospholipids; Polyphenols; Temperature | 2014 |
Post-harvest induced production of salvianolic acids and significant promotion of antioxidant properties in roots of Salvia miltiorrhiza (Danshen).
Topics: Alkenes; Antioxidants; Free Radical Scavengers; Plant Roots; Polyphenols; Salvia miltiorrhiza | 2014 |
[Studies on hydroxyapatite applicatied in coprecipitate of total salvianolic acids phospholipid complex].
Topics: Alkenes; Chemical Precipitation; Chemistry, Pharmaceutical; Durapatite; Phospholipids; Polyphenols; Time Factors | 2014 |
The anti-apoptotic and cardioprotective effects of salvianolic acid a on rat cardiomyocytes following ischemia/reperfusion by DUSP-mediated regulation of the ERK1/2/JNK pathway.
Topics: Alkenes; Animals; Apoptosis; Blood Pressure; Blotting, Western; Cardiotonic Agents; Dual-Specificity Phosphatases; Heart Function Tests; Heart Rate; Ischemic Preconditioning, Myocardial; MAP Kinase Signaling System; Molecular Structure; Myocytes, Cardiac; Polyphenols; Rats; Reperfusion Injury | 2014 |
Salvianolic acids T and U: a pair of atropisomeric trimeric caffeic acids derivatives from root of Salvia miltiorrhiza.
Topics: Alkenes; Caffeic Acids; Molecular Structure; Plant Roots; Polyphenols; Salvia miltiorrhiza | 2014 |
Salvianolic Acid a prevents the pathological progression of hepatic fibrosis in high-fat diet-fed and streptozotocin-induced diabetic rats.
Topics: Actins; Alkenes; Animals; Caffeic Acids; Diabetes Mellitus, Experimental; Diet, High-Fat; Disease Progression; Lactates; Liver; Liver Cirrhosis; Phytotherapy; Polyphenols; Rats, Sprague-Dawley; Streptozocin; Transforming Growth Factor beta1 | 2014 |
Salvianolic acid Y: a new protector of PC12 cells against hydrogen peroxide-induced injury from Salvia officinalis.
Topics: Alkenes; Animals; Benzofurans; Cytoprotection; Drugs, Chinese Herbal; Hydrogen Peroxide; Neuroprotective Agents; PC12 Cells; Polyphenols; Proton Magnetic Resonance Spectroscopy; Rats; Salvia officinalis | 2015 |
Salvianolic acids attenuate rat hippocampal injury after acute CO poisoning by improving blood flow properties.
Topics: Alkenes; Animals; Brain Injuries; Carbon Monoxide; Carbon Monoxide Poisoning; Disease Models, Animal; Erythrocytes; Hematocrit; Hemorheology; Hippocampus; Humans; Malondialdehyde; Mannitol; Neurotoxicity Syndromes; Polyphenols; Rats | 2015 |
Screening of mammalian target of rapamycin inhibitors in natural product extracts by capillary electrophoresis in combination with high performance liquid chromatography-tandem mass spectrometry.
Topics: Adaptor Proteins, Signal Transducing; Alkenes; Biological Products; Cell Cycle Proteins; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Electrophoresis, Capillary; Enzyme Inhibitors; Fluoresceins; High-Throughput Screening Assays; Humans; Morpholines; Phosphoproteins; Plant Extracts; Polyphenols; Salvia miltiorrhiza; Small Molecule Libraries; Tandem Mass Spectrometry; TOR Serine-Threonine Kinases | 2015 |
Screening of direct thrombin inhibitors from Radix Salviae Miltiorrhizae by a peak fractionation approach.
Topics: Abietanes; Alkenes; Antithrombins; Chromatography, High Pressure Liquid; Computer Simulation; Drug Evaluation, Preclinical; Models, Molecular; Plant Roots; Polyphenols; Receptors, Drug; Reproducibility of Results; Salvia miltiorrhiza | 2015 |
Compound Astragalus and Salvia miltiorrhiza extracts modulate MAPK-regulated TGF-β/Smad signaling in hepatocellular carcinoma by multi-target mechanism.
Topics: Alkenes; Animals; Astragalus propinquus; Carcinoma, Hepatocellular; Diethylnitrosamine; Down-Regulation; Gene Expression; Hep G2 Cells; Hepatic Stellate Cells; Humans; Karyopherins; Liver Neoplasms; Male; MAP Kinase Signaling System; Plant Extracts; Plasminogen Activator Inhibitor 1; Polyphenols; Polysaccharides; Rats; Receptors, Cytoplasmic and Nuclear; Salvia miltiorrhiza; Saponins; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta1; Triterpenes; Up-Regulation | 2015 |
Antidiabetic Effect of Salvianolic Acid A on Diabetic Animal Models via AMPK Activation and Mitochondrial Regulation.
Topics: Alkenes; Alloxan; AMP-Activated Protein Kinases; Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Diet, High-Fat; Eating; Gene Expression Regulation; Hep G2 Cells; Humans; Hypoglycemic Agents; Membrane Potential, Mitochondrial; Mice; Mitochondria; Polyphenols; Rats; Signal Transduction; Streptozocin | 2015 |
Combination Therapy of Salvianolic Acid and Fluoxetine Improves the Cognitive Function of Rats with Chronic Stress-induced Depression.
Topics: Alkenes; Animals; Antidepressive Agents, Second-Generation; Chronic Disease; Cognition Disorders; Depressive Disorder; Disease Models, Animal; Drug Therapy, Combination; Fluoxetine; Male; Maze Learning; Polyphenols; Rats; Rats, Sprague-Dawley; Stress, Psychological | 2016 |
The Mixture of Salvianolic Acids from Salvia miltiorrhiza and Total Flavonoids from Anemarrhena asphodeloides Attenuate Sulfur Mustard-Induced Injury.
Topics: Alkenes; Anemarrhena; Animals; Chemical Warfare Agents; Flavonoids; Intestine, Small; Liver; Male; Mustard Gas; Polyphenols; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Testis | 2015 |
Effect of salvianolic acid A and C compatibility on inflammatory cytokines in rats with unilateral ureteral obstruction.
Topics: Alkenes; Animals; Caffeic Acids; Chemokine CCL5; Chemokine CXCL10; Cytokines; Drugs, Chinese Herbal; Humans; Lactates; Male; Polyphenols; Rats; Ureteral Obstruction | 2015 |
Bioactive minor components of the total salvianolic acids injection prepared from Salvia miltiorrhiza Bge.
Topics: Alkenes; Carbon-13 Magnetic Resonance Spectroscopy; Molecular Structure; Polyphenols; Proton Magnetic Resonance Spectroscopy; Salvia miltiorrhiza | 2016 |
Prevention of vascular smooth muscle cell proliferation and injury-induced neointimal hyperplasia by CREB-mediated p21 induction: An insight from a plant polyphenol.
Topics: Alkenes; Animals; Carotid Artery Injuries; Cell Cycle Checkpoints; Cell Proliferation; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase Inhibitor p21; Humans; Hyperplasia; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Polyphenols; Rats, Sprague-Dawley; Signal Transduction; Tunica Intima | 2016 |
Characterization of metabolites in rats after intravenous administration of salvianolic acid for injection by ultra-performance liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry.
Topics: Administration, Intravenous; Alkenes; Animals; Chromatography, Liquid; Limit of Detection; Male; Mass Spectrometry; Polyphenols; Rats; Rats, Wistar | 2016 |
Quantitative analysis of highly similar salvianolic acids with 1H qNMR for quality control of traditional Chinese medicinal preparation Salvianolate Lyophilized Injection.
Topics: Alkenes; Chromatography, High Pressure Liquid; Freeze Drying; Medicine, Chinese Traditional; Polyphenols; Proton Magnetic Resonance Spectroscopy; Quality Control | 2016 |
Development and validation of a UFLC-MS/MS method for determination of 7'(Z)-(8″S, 8‴S)-epi-salvianolic acid E, (7'R, 8'R, 8″S, 8‴S)-epi-salvianolic acid B and salvianolic acid B in rat plasma and its application to pharmacokinetic studies.
Topics: Alkenes; Animals; Benzofurans; Chromatography, High Pressure Liquid; Drug Stability; Linear Models; Male; Polyphenols; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2016 |
Improving the antioxidant activity and enriching salvianolic acids by the fermentation of Salvia miltiorrhizae with Geomyces luteus.
Topics: Alkenes; Antioxidants; Ascomycota; Benzofurans; Biphenyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fermentation; Phenols; Picrates; Polyphenols; Salvia miltiorrhiza; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared | 2016 |
New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats.
Topics: Alkenes; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Carrier Proteins; Cell Cycle Proteins; Dietary Fats; Hep G2 Cells; Humans; Lipid Metabolism; Liver; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Non-alcoholic Fatty Liver Disease; Polyphenols; Rats; Rats, Sprague-Dawley | 2016 |
Quantitatively metabolic profiles of salvianolic acids in rats after gastric-administration of Salvia miltiorrhiza extract.
Topics: Alkenes; Animals; Benzaldehydes; Caffeic Acids; Catechols; Drug Stability; Drugs, Chinese Herbal; Hydroxybenzoates; Lactates; Male; Metabolome; Molecular Structure; Polyphenols; Rats; Rats, Wistar; Salvia miltiorrhiza | 2016 |
Effects of the Nrf2 Protein Modulator Salvianolic Acid A Alone or Combined with Metformin on Diabetes-associated Macrovascular and Renal Injury.
Topics: Alkenes; Animals; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Nephropathies; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Heme Oxygenase-1; Male; Membrane Proteins; Metformin; Mice; Mice, Inbred ICR; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Polyphenols | 2016 |
Neuroprotective Effect of Salvianolic Acids against Cerebral Ischemia/Reperfusion Injury.
Topics: Alkenes; Animals; Apoptosis; Astrocytes; Blotting, Western; Brain Ischemia; Infarction, Middle Cerebral Artery; Male; Membrane Potential, Mitochondrial; Mitochondria; Neuroprotective Agents; Polyphenols; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction | 2016 |
Ectopic Expression of DREB Transcription Factor, AtDREB1A, Confers Tolerance to Drought in Transgenic Salvia miltiorrhiza.
Topics: Abietanes; Alkenes; Arabidopsis; Arabidopsis Proteins; Catalase; Cluster Analysis; Droughts; Ectopic Gene Expression; Gene Expression Regulation, Plant; Malondialdehyde; Plant Roots; Plants, Genetically Modified; Polyphenols; Salvia miltiorrhiza; Sequence Analysis, RNA; Stress, Physiological; Superoxide Dismutase; Transcription Factors; Water | 2016 |
Lemon balm extract (Melissa officinalis, L.) promotes melanogenesis and prevents UVB-induced oxidative stress and DNA damage in a skin cell model.
Topics: Alkenes; Antioxidants; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cinnamates; Depsides; DNA Damage; Humans; Inflammation; Keratinocytes; Lipids; Melanocytes; Melissa; Oxidative Stress; Oxygen; Plant Extracts; Polyphenols; Reactive Oxygen Species; Rosmarinic Acid; Skin; Tandem Mass Spectrometry; Ultraviolet Rays | 2016 |
Simultaneous determination and pharmacokinetic study of four phenolic acids in rat plasma using UFLC-MS/MS after intravenous administration of salvianolic acid for injection.
Topics: Administration, Intravenous; Alkenes; Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Hydroxybenzoates; Male; Polyphenols; Rats; Rats, Wistar; Salvia miltiorrhiza; Tandem Mass Spectrometry | 2017 |
Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
Topics: Abietanes; Alkenes; Arabidopsis Proteins; Biosynthetic Pathways; Dehydration; Gene Expression; Gene Expression Regulation, Plant; Plant Roots; Plants, Genetically Modified; Polyphenols; Salvia miltiorrhiza; Transcription Factors; Up-Regulation | 2017 |
The effect of Chinese herbs and its effective components on coronary heart disease through PPARs-PGC1α pathway.
Topics: Alkenes; Animals; Cholesterol; Coronary Disease; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Heart; Lipid Metabolism; Male; MAP Kinase Signaling System; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Peroxisome Proliferator-Activated Receptors; Phosphatidylinositol 3-Kinases; Phytotherapy; Polyphenols; Proto-Oncogene Proteins c-akt; Random Allocation; Rats, Sprague-Dawley; Retinoid X Receptor alpha; Saponins | 2016 |
A mini-network balance model for evaluating the progression of cardiovascular complications in Goto-Kakizaki rats.
Topics: Alkenes; Animals; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus, Type 2; Disease Progression; Drug Therapy, Combination; Hypoglycemic Agents; Metformin; Models, Biological; Polyphenols; Rats, Wistar | 2017 |
Salvianolic Acids for Injection (SAFI) suppresses inflammatory responses in activated microglia to attenuate brain damage in focal cerebral ischemia.
Topics: Alkenes; Animals; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Inflammation; Interleukin-1beta; Interleukin-6; Male; Microglia; Neuroprotective Agents; NF-kappa B; Polyphenols; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Stroke; Toll-Like Receptor 4 | 2017 |
Simultaneous determination of eight bioactive components of Qishen Yiqi dripping pills in rat plasma using UFLC-MS/MS and its application to a pharmacokinetic study.
Topics: Alkenes; Animals; Benzaldehydes; Caffeic Acids; Catechols; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Drugs, Chinese Herbal; Ginsenosides; Glucosides; Hydroxybenzoates; Isoflavones; Limit of Detection; Male; Polyphenols; Rats; Rats, Sprague-Dawley; Rosmarinic Acid; Saponins; Tandem Mass Spectrometry; Triterpenes | 2017 |
Amelioration of cognitive impairments in APPswe/PS1dE9 mice is associated with metabolites alteration induced by total salvianolic acid.
Topics: Alkenes; Amyloid beta-Protein Precursor; Animals; Blood Glucose; Cholesterol, HDL; Cholesterol, LDL; Cognition Disorders; Cognitive Dysfunction; Enzyme-Linked Immunosorbent Assay; Gas Chromatography-Mass Spectrometry; Hippocampus; Male; Mice; Mice, Inbred C57BL; Polyphenols; Triglycerides | 2017 |
Minor compounds of the high purity salvianolic acid B freeze-dried powder from Salvia miltiorrhiza and antibacterial activity assessment.
Topics: Acinetobacter baumannii; Alkenes; Anti-Bacterial Agents; Benzofurans; Caffeic Acids; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Freeze Drying; Methicillin-Resistant Staphylococcus aureus; Molecular Structure; Polyphenols; Powders; Salvia miltiorrhiza | 2018 |
Salvianolic acids enhance cerebral angiogenesis and neurological recovery by activating JAK2/STAT3 signaling pathway after ischemic stroke in mice.
Topics: Alkenes; Animals; Brain Ischemia; Cerebral Cortex; Janus Kinase 2; Male; Mice; Mice, Inbred C57BL; Microvessels; Neovascularization, Physiologic; Neurons; Polyphenols; Random Allocation; Recovery of Function; Signal Transduction; STAT3 Transcription Factor; Stroke | 2017 |
[Preparation and characterization of salvianolic acids-tanshinones composite powder for inhalation via co-micronized method].
Topics: Abietanes; Alkenes; Chemistry, Pharmaceutical; Drugs, Chinese Herbal; Dry Powder Inhalers; Microscopy, Electron, Scanning; Particle Size; Polyphenols; Powders; Salvia miltiorrhiza; Wettability; X-Ray Diffraction | 2016 |
[Protective effect of seven kinds of phenolic acids of total salvianolic acids components on human umbilical vein endothelial cells with hypoxic injury].
Topics: Alkenes; Cell Hypoxia; Cell Survival; Drugs, Chinese Herbal; Human Umbilical Vein Endothelial Cells; Humans; Hydroxybenzoates; Malondialdehyde; Oxidative Stress; Polyphenols; Protective Agents; Superoxide Dismutase | 2016 |
Salvianolic Acids for Injection (SAFI) promotes functional recovery and neurogenesis via sonic hedgehog pathway after stroke in mice.
Topics: Alkenes; Animals; Drugs, Chinese Herbal; Hedgehog Proteins; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Polyphenols; Random Allocation; Recovery of Function; Signal Transduction; Stroke; Veratrum Alkaloids | 2017 |
[Monitoring method for macroporous resin column chromatography process of salvianolic acids based on near infrared spectroscopy].
Topics: Alkenes; Chromatography; Drugs, Chinese Herbal; Least-Squares Analysis; Polyphenols; Spectroscopy, Near-Infrared | 2016 |
[Construction of NIRS-based process analytical system for production of salvianolic acid for injection and relative discussion].
Topics: Alkenes; Chemistry, Pharmaceutical; Chromatography; Drugs, Chinese Herbal; Injections; Medicine, Chinese Traditional; Polyphenols; Spectroscopy, Near-Infrared | 2016 |
Salvianolic acid A reverses cisplatin resistance in lung cancer A549 cells by targeting c-met and attenuating Akt/mTOR pathway.
Topics: Adenocarcinoma; Alkenes; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Cisplatin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Lung Neoplasms; Phytotherapy; Polyphenols; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Salvia miltiorrhiza; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation | 2017 |
Prescription Optimization and Oral Bioavailability Study of Salvianolic Acid Extracts W/O/W Multiple Emulsion.
Topics: Administration, Oral; Alkenes; Animals; Biological Availability; Brain Infarction; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Compounding; Emulsifying Agents; Emulsions; Hematologic Diseases; Hemorheology; Humans; Hydrophobic and Hydrophilic Interactions; Injections, Intravenous; Male; Oils; Particle Size; Polyphenols; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Water | 2017 |
Simultaneous determination and tissue distribution studies of four phenolic acids in rat tissue by UFLC-MS/MS after intravenous administration of salvianolic acid for injection.
Topics: Alkenes; Animals; Chromatography, High Pressure Liquid; Hydroxybenzoates; Linear Models; Male; Polyphenols; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2018 |
SmJAZ8 acts as a core repressor regulating JA-induced biosynthesis of salvianolic acids and tanshinones in Salvia miltiorrhiza hairy roots.
Topics: Abietanes; Alkenes; Co-Repressor Proteins; Cyclopentanes; Oxylipins; Plant Proteins; Plant Roots; Polyphenols; Salvia | 2018 |
Is comfrey root more than toxic pyrrolizidine alkaloids? Salvianolic acids among antioxidant polyphenols in comfrey (Symphytum officinale L.) roots.
Topics: Alkenes; Antioxidants; Chromatography, High Pressure Liquid; Comfrey; Plant Roots; Polyphenols; Pyrrolizidine Alkaloids; Tandem Mass Spectrometry | 2018 |
Salvianolic acid A ameliorates renal ischemia/reperfusion injury by activating Akt/mTOR/4EBP1 signaling pathway.
Topics: Acute Kidney Injury; Alkenes; Animals; Apoptosis; Biomarkers; Blood Urea Nitrogen; Carrier Proteins; Cell Line; Creatinine; Cytoprotection; Disease Models, Animal; Humans; Intracellular Signaling Peptides and Proteins; Kidney; Male; Oxidative Stress; Phosphoproteins; Phosphorylation; Polyphenols; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Renal Agents; Reperfusion Injury; Signal Transduction; TOR Serine-Threonine Kinases | 2018 |
Simultaneous identification of three pseudoallergic components in Danshen injection by using high-expression Mas-related G protein coupled receptor X2 cell membrane chromatography coupled online to HPLC-ESI-MS/MS.
Topics: Alkenes; Animals; Caffeic Acids; Cell Line; Cell Membrane; Chromatography; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Humans; Lactates; Male; Mice; Molecular Structure; Nerve Tissue Proteins; Polyphenols; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Salvia miltiorrhiza; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2018 |
A quality marker study on salvianolic acids for injection.
Topics: Alkenes; Animals; Benzofurans; Biomarkers; Brain; Brain Ischemia; Cell Line; Cinnamates; Depsides; Drugs, Chinese Herbal; Endothelium, Vascular; Injections; Interleukin-1; Interleukin-6; Male; Polyphenols; Quality Control; Rats, Sprague-Dawley; Rosmarinic Acid; Superoxide Dismutase | 2018 |
Computational insights into β-site amyloid precursor protein enzyme 1 (BACE1) inhibition by tanshinones and salvianolic acids from Salvia miltiorrhiza via molecular docking simulations.
Topics: Abietanes; Alkenes; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Computational Biology; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Lamiaceae; Molecular Docking Simulation; Molecular Structure; Polyphenols; Structure-Activity Relationship | 2018 |
Preparation and Quality Evaluation of Salvianolic Acids and Tanshinones Dry Powder Inhalation.
Topics: Abietanes; Alkenes; Chemistry, Pharmaceutical; Dry Powder Inhalers; Polyphenols; Quality Control | 2018 |
Angioedema and Hemorrhage After 4.5-Hour tPA (Tissue-Type Plasminogen Activator) Thrombolysis Ameliorated by T541 via Restoring Brain Microvascular Integrity.
Topics: Alkenes; Animals; Antigens, CD; Astragalus Plant; Brain; Brain Edema; Cadherins; Carotid Artery Thrombosis; Cell Adhesion Molecules; Cerebrovascular Circulation; Claudin-5; Collagen Type IV; Disease Models, Animal; Drug Combinations; Drugs, Chinese Herbal; Electron Transport Complex I; Electron Transport Complex II; Electron Transport Complex IV; Intracranial Hemorrhages; Laminin; Male; Mice; Occludin; Panax notoginseng; Polyphenols; Receptors, Cell Surface; Reperfusion Injury; Saponins; Tissue Plasminogen Activator; Zonula Occludens-1 Protein | 2018 |
Salvianolic acid inhibits the effects of high glucose on vascular endothelial dysfunction by modulating the Sirt1-eNOS pathway.
Topics: Alkenes; Gene Expression Regulation, Enzymologic; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Nitric Oxide Synthase Type III; Polyphenols; Signal Transduction; Sirtuin 1 | 2019 |
Impact of Sodium
Topics: Administration, Oral; Alkenes; Animals; Biological Availability; Biological Transport; Caco-2 Cells; Caprylates; Cell Membrane Permeability; Ginsenosides; Humans; Intestinal Absorption; Intestines; Male; Polyphenols; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2018 |
Correlation between macroscopic characteristics and tissue-specific chemical profiling of the root of Salvia miltiorrhiza.
Topics: Abietanes; Alkenes; Chromatography, High Pressure Liquid; Color; Drugs, Chinese Herbal; Plant Roots; Polyphenols; Salvia miltiorrhiza; Tandem Mass Spectrometry | 2018 |
Salvianolic acids improve liver lipid metabolism in ovariectomized rats via blocking STAT-3/SREBP1 signaling.
Topics: Alkenes; Animals; Drugs, Chinese Herbal; Female; Humans; Lipid Metabolism; Liver; Obesity; Ovariectomy; Polyphenols; Postmenopause; Rats; Salvia miltiorrhiza; Signal Transduction; STAT3 Transcription Factor; Sterol Regulatory Element Binding Protein 1; Triglycerides | 2018 |
Styryl-cinnamate hybrid inhibits glioma by alleviating translation, bioenergetics and other key cellular responses leading to apoptosis.
Topics: Alkenes; Animals; Cell Line, Tumor; Cell Proliferation; Cinnamates; Computational Chemistry; Cyclin D; Gene Expression Regulation, Neoplastic; Glioma; Heterografts; Humans; Mice; Neoplasm Proteins; Polyphenols; Protein Interaction Maps; Proteomics; Small Molecule Libraries | 2019 |
Facile preparation of a controlled-release tubular scaffold for blood vessel implantation.
Topics: Alkenes; Animals; Blood Vessel Prosthesis Implantation; Carotid Arteries; Cell Adhesion; Cell Proliferation; Cells, Cultured; Female; Gelatin; Human Umbilical Vein Endothelial Cells; Humans; Nanoparticles; Particle Size; Polyphenols; Polyurethanes; Porosity; Rabbits; Silicon Dioxide; Surface Properties; Tissue Engineering; Tissue Scaffolds | 2019 |
Improved dialysis removal of protein-bound uremic toxins by salvianolic acids.
Topics: Alkenes; Animals; Binding, Competitive; Cresols; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Indican; Male; Microdialysis; Polyphenols; Protein Binding; Proteins; Rats, Sprague-Dawley; Renal Dialysis; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Toxins, Biological; Uremia | 2019 |
Salvianolic acid B combined with mesenchymal stem cells contributes to nucleus pulposus regeneration.
Topics: Alkenes; Animals; Disease Models, Animal; Intervertebral Disc Degeneration; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Nucleus Pulposus; Polyphenols; Rabbits; Regeneration | 2020 |
Microbial inoculant and garbage enzyme reduced cadmium (Cd) uptake in Salvia miltiorrhiza (Bge.) under Cd stress.
Topics: Abietanes; Alkenes; Biodegradation, Environmental; Biomass; Cadmium; Plant Roots; Polyphenols; Rhizosphere; Salvia miltiorrhiza; Soil Microbiology; Soil Pollutants | 2020 |
Salvianolic Acid A Ameliorates Early-Stage Atherosclerosis Development by Inhibiting NLRP3 Inflammasome Activation in Zucker Diabetic Fatty Rats.
Topics: Alkenes; Animals; Atherosclerosis; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Inflammasomes; Lipids; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Polyphenols; Rats; Rats, Zucker | 2020 |
Salvia miltiorrhiza stem-leaf active components of salvianolic acids and flavonoids improved the hemorheological disorder and vascular endothelial function on microcirculation dysfunction rats.
Topics: Alkenes; Animals; Endothelial Cells; Flavonoids; Hemorheology; Male; Microcirculation; Plant Leaves; Plant Stems; Polyphenols; Rats; Rats, Wistar; Salvia miltiorrhiza | 2020 |
[Study on application of salvianolic acids reference extract in quality control of Salvia miltiorrhiza and salvianolic acids for injection].
Topics: Alkenes; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Polyphenols; Quality Control; Reproducibility of Results; Salvia miltiorrhiza | 2019 |
[Migration of phenolic active ingredients in Danshen Dizhuye during ultrafiltration of hollow fiber membrane].
Topics: Alkenes; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Polyphenols; Salvia miltiorrhiza; Ultrafiltration | 2020 |
SmMYB2 promotes salvianolic acid biosynthesis in the medicinal herb Salvia miltiorrhiza.
Topics: Alkenes; Gene Expression Regulation, Plant; Plant Proteins; Plants, Medicinal; Polyphenols; Salvia miltiorrhiza | 2020 |
Salvianolic Acid Alleviated Blood-Brain Barrier Permeability in Spontaneously Hypertensive Rats by Inhibiting Apoptosis in Pericytes via P53 and the Ras/Raf/MEK/ERK Pathway.
Topics: Alkenes; Animals; Apoptosis; Blood-Brain Barrier; Cells, Cultured; Dose-Response Relationship, Drug; MAP Kinase Signaling System; Molecular Structure; Pericytes; Permeability; Polyphenols; Rats; Rats, Inbred SHR; Rats, Wistar; Structure-Activity Relationship; Tumor Suppressor Protein p53 | 2020 |
The efficacy and safety of salvianolic acids on acute cerebral infarction treatment: A protocol for systematic review and meta analysis.
Topics: Activities of Daily Living; Acute Disease; Alkenes; Cerebral Infarction; Cognition; Combined Modality Therapy; Humans; Meta-Analysis as Topic; Polyphenols; Randomized Controlled Trials as Topic; Research Design; Systematic Review as Topic | 2020 |
Polyphenol composition and biological activity of Thymus citriodorus and Thymus vulgaris: Comparison with endemic Iberian Thymus species.
Topics: Alkenes; Antioxidants; Caco-2 Cells; Cell Proliferation; Cinnamates; Cluster Analysis; Depsides; Food Analysis; Hep G2 Cells; Humans; Plant Extracts; Polyphenols; Rosmarinic Acid; Thymus Plant | 2020 |
smi-miR396b targeted SmGRFs, SmHDT1, and SmMYB37/4 synergistically regulates cell growth and active ingredient accumulation in Salvia miltiorrhiza hairy roots.
Topics: Abietanes; Abscisic Acid; Acetates; Alkenes; Anthocyanins; Binding Sites; Biomass; Cell Proliferation; Cyclopentanes; Droughts; Gene Expression Profiling; Gene Expression Regulation, Plant; Gene Ontology; Gene Regulatory Networks; Gibberellins; MicroRNAs; Oxylipins; Phylogeny; Plant Proteins; Plant Roots; Plants, Genetically Modified; Polyphenols; Propanols; RNA Stability; Salt Stress; Salvia miltiorrhiza; Secondary Metabolism; Terpenes; Transcription Factors; Transcription, Genetic; Transcriptome | 2020 |
Differential distribution of characteristic constituents in root, stem and leaf tissues of Salvia miltiorrhiza using MALDI mass spectrometry imaging.
Topics: Abietanes; Alkenes; China; Chromatography, Liquid; Phytochemicals; Plant Leaves; Plant Roots; Plant Stems; Plants, Medicinal; Polyphenols; Salvia miltiorrhiza; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2020 |
Integrative omic and transgenic analyses reveal the positive effect of ultraviolet-B irradiation on salvianolic acid biosynthesis through upregulation of SmNAC1.
Topics: Alkenes; Enzymes; Gene Expression Regulation, Plant; Metabolomics; Plant Leaves; Plant Proteins; Plants, Genetically Modified; Polyphenols; Proteomics; RNA Interference; Salvia miltiorrhiza; Transcription Factors; Ultraviolet Rays; Up-Regulation | 2020 |
A HPLC-DAD-MS/MS Method for Simultaneous Determination of Six Active Ingredients of
Topics: Alkenes; Animals; Chromatography, High Pressure Liquid; Female; Infusions, Intravenous; Male; Molecular Structure; Plasma; Polyphenols; Pyrazines; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Tandem Mass Spectrometry | 2021 |
Comparative pharmacokinetics of seven bioactive components in normal, sham-operated, and myocardial ischemia-reperfusion injury rats after oral administration of the Salvia Miltiorrhiza-Moutan Cortex herb pair.
Topics: Abietanes; Acids, Carbocyclic; Administration, Oral; Alkenes; Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Linear Models; Male; Myocardial Reperfusion Injury; Paeonia; Polyphenols; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Salvia miltiorrhiza; Sensitivity and Specificity | 2021 |
UPLC/MS-based untargeted metabolomics reveals the changes of metabolites profile of Salvia miltiorrhiza bunge during Sweating processing.
Topics: Abietanes; Alkenes; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Medicine, Chinese Traditional; Metabolomics; Multivariate Analysis; Plant Roots; Polyphenols; Salvia miltiorrhiza; Spectrometry, Mass, Electrospray Ionization | 2020 |
Salvianolic Acids for Injection alleviates cerebral ischemia/reperfusion injury by switching M1/M2 phenotypes and inhibiting NLRP3 inflammasome/pyroptosis axis in microglia in vivo and in vitro.
Topics: Alkenes; Amino Acid Transport System ASC; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Brain Ischemia; Calcium-Binding Proteins; Caspase 1; Cell Survival; Cells, Cultured; Disease Models, Animal; Inflammasomes; Injections, Intraperitoneal; Interleukin-1beta; Intracellular Signaling Peptides and Proteins; Male; Microfilament Proteins; Microglia; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphate-Binding Proteins; Polyphenols; Pyroptosis; Rats, Sprague-Dawley; Reperfusion Injury | 2021 |
Three salvianolic acids inhibit 2019-nCoV spike pseudovirus viropexis by binding to both its RBD and receptor ACE2.
Topics: Alkenes; Angiotensin-Converting Enzyme 2; Benzofurans; Caffeic Acids; Cell Survival; COVID-19 Drug Treatment; HEK293 Cells; Humans; Lactates; Molecular Structure; Polyphenols; Protein Binding; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Virus Internalization | 2021 |
In vitro Preparation and Evaluation of Sustained-Release Microcapsules of Salvianolic Acid.
Topics: Alkenes; Capsules; Delayed-Action Preparations; Polyphenols | 2021 |
Neurovascular protection of salvianolic acid B and ginsenoside Rg1 combination against acute ischemic stroke in rats.
Topics: Alkenes; Animals; Blood-Brain Barrier; Brain; Ginsenosides; Ischemic Stroke; Male; Neuroprotective Agents; Polyphenols; Rats; Rats, Sprague-Dawley | 2021 |
Clinical Observation of Salvianolic Acid Combined with Panax Notoginseng Saponins Combined with Basic Nursing Intervention on Cerebral Ischemia-Reperfusion Injury in Rats.
Topics: Alkenes; Animals; bcl-2-Associated X Protein; Caspase 3; Female; Humans; Infarction; Interleukin-6; Interleukin-8; Male; NF-kappa B; Panax notoginseng; Polyphenols; Rats; Rats, Wistar; Reperfusion Injury; Saponins; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Water | 2022 |
Interaction study of salvianolic acids for injection on pharmacokinetics of clopidogrel in rats using LC-MS/MS.
Topics: Alkenes; Animals; Chromatography, Liquid; Clopidogrel; Cytochrome P-450 Enzyme System; Humans; Isoenzymes; Platelet Aggregation Inhibitors; Polyphenols; Rats; Tandem Mass Spectrometry | 2022 |
Overexpression of SmLAC25 promotes lignin accumulation and decreases salvianolic acid content in Salvia miltiorrhiza.
Topics: Alkenes; Gene Expression Regulation, Plant; Lignin; Plant Roots; Polyphenols; Salvia miltiorrhiza | 2022 |
[Study on metabolites in vivo of Dangefentong Capsules based on UHPLC-Q/Orbitrap-MS/MS].
Topics: Abietanes; Acetonitriles; Alkenes; Animals; Capsules; Chromatography, High Pressure Liquid; Dogs; Drugs, Chinese Herbal; Flavonoids; Formates; Male; Polyphenols; Pueraria; Tandem Mass Spectrometry | 2022 |