Page last updated: 2024-08-23

alkenes and okadaic acid

alkenes has been researched along with okadaic acid in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (31.58)18.2507
2000's13 (68.42)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, HJ; Bradbury, EM; Guo, XW; Roberge, M; Swank, RA; Th'ng, JP; Tudan, C1
Anderson, H; Roberge, M1
Cheng, A; Honkanen, RE; Walsh, AH1
Takai, A1
Balczon, R; Cheng, A; Honkanen, RE; Koons, JS; Walsh, AH; Zuo, Z1
Dounay, AB; Forsyth, CJ1
Douglas, P; Lees-Miller, SP; Moorhead, GB; Ye, R1
Biade, S; Boyd, JT; Chapman, JD; Stobbe, CC1
Bastan, R; Peachell, PT; Peirce, MJ1
McCluskey, A; Sakoff, JA; Sim, AT1
Farndale, RW; Sundaresan, P1
Bock, PJ; Faulkner, NE; Lane, BR; Markovitz, DM1
Fandrich, RR; Jeyaraman, M; Kardami, E; Lukas, A; Tanguy, S1
Göke, B; Groblewski, GE; Krzykowski, KJ; Schäfer, C; Steffen, H1
Ballard, DW; Carter, RS; Gomez, RJ; Khan, WN; Kray, AE; Llanes, JM; Pennington, KN; Sanders, LE; Wadzinski, BE1
Boynton, A; Messner, DJ; Romeo, C; Rossie, S1
Fang, L; Willis, WD; Wu, J; Zhang, X1
Li, Z; Tu, X; Wang, CC1
Hanaoka, F; Hirano, T; Ikehara, T; Imamoto, N; Imamura, S; Kimura, K; Maeshima, K; Murayama, A; Takemoto, A; Watanabe, Y; Yamaguchi, K; Yanagisawa, J; Yokoyama, S1

Reviews

2 review(s) available for alkenes and okadaic acid

ArticleYear
[Naturally occurring toxins with specific inhibitory activity against protein serine/threonine phosphatases 1 and 2A].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1998, Volume: 43, Issue:8 Suppl

    Topics: Alkenes; Animals; Antifungal Agents; Cantharidin; Marine Toxins; Microcystins; Okadaic Acid; Oxazoles; Peptides, Cyclic; Phosphoprotein Phosphatases; Polyenes; Pyrans; Pyrones; Spiro Compounds

1998
Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies.
    Journal of medicinal chemistry, 2002, Mar-14, Volume: 45, Issue:6

    Topics: Alkenes; Antibiotics, Antineoplastic; Antifungal Agents; Cantharidin; Crystallography, X-Ray; Cyclosporine; Enzyme Inhibitors; Humans; Microcystins; Models, Molecular; Okadaic Acid; Peptides, Cyclic; Phosphoprotein Phosphatases; Polyenes; Pyrans; Pyrones; Spiro Compounds; Structure-Activity Relationship

2002

Other Studies

17 other study(ies) available for alkenes and okadaic acid

ArticleYear
Chromosome condensation induced by fostriecin does not require p34cdc2 kinase activity and histone H1 hyperphosphorylation, but is associated with enhanced histone H2A and H3 phosphorylation.
    The EMBO journal, 1995, Mar-01, Volume: 14, Issue:5

    Topics: Alkaloids; Alkenes; Animals; CDC2 Protein Kinase; Chromosomes; Cyclins; Ethers, Cyclic; G2 Phase; Genes, cdc; Histones; Mice; Mitosis; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Polyenes; Protamine Kinase; Protein Kinase C; Protein Phosphatase 1; Pyrones; Staurosporine; Temperature; Tumor Cells, Cultured

1995
Topoisomerase II inhibitors affect entry into mitosis and chromosome condensation in BHK cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1996, Volume: 7, Issue:1

    Topics: Aclarubicin; Alkenes; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Cycle Proteins; Cell Line; Chromosomes; Cricetinae; DNA-Binding Proteins; Enzyme Inhibitors; Etoposide; G2 Phase; Guanine Nucleotide Exchange Factors; Kidney; Mitosis; Nuclear Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Polyenes; Pyrones; Razoxane; Temperature; Thiobarbiturates; Topoisomerase II Inhibitors

1996
Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A.
    FEBS letters, 1997, Oct-27, Volume: 416, Issue:3

    Topics: Alkenes; Animals; Antibiotics, Antineoplastic; Brain; Cattle; Enzyme Inhibitors; Isoenzymes; Kinetics; Muscle, Skeletal; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylase Kinase; Polyenes; Pyrones; Rabbits; Recombinant Fusion Proteins

1997
Fostriecin-mediated G2-M-phase growth arrest correlates with abnormal centrosome replication, the formation of aberrant mitotic spindles, and the inhibition of serine/threonine protein phosphatase activity.
    Cancer research, 1998, Aug-15, Volume: 58, Issue:16

    Topics: Alkenes; Animals; Antineoplastic Agents; Cantharidin; Centrosome; CHO Cells; Cricetinae; Enzyme Inhibitors; G2 Phase; Mitosis; Okadaic Acid; Phosphoprotein Phosphatases; Polyenes; Pyrones; RNA, Messenger; Spindle Apparatus; Tumor Suppressor Protein p53

1998
Abbreviated synthesis of the C3-C14 (substituted 1,7-dioxaspiro[5.5]undec-3-ene) system of okadaic acid.
    Organic letters, 1999, Aug-12, Volume: 1, Issue:3

    Topics: Alkenes; Enzyme Inhibitors; Lactones; Okadaic Acid; Spiro Compounds

1999
Protein phosphatases regulate DNA-dependent protein kinase activity.
    The Journal of biological chemistry, 2001, Jun-01, Volume: 276, Issue:22

    Topics: Alkenes; Antigens, Nuclear; Catalysis; Catalytic Domain; Cell Line; Cells, Cultured; DNA Damage; DNA Helicases; DNA Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Ku Autoantigen; Microcystins; Nuclear Proteins; Okadaic Acid; Peptides, Cyclic; Phosphates; Phosphoprotein Phosphatases; Phosphorylation; Polyenes; Precipitin Tests; Protein Binding; Protein Kinases; Protein Phosphatase 1; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Pyrones; Recombinant Proteins; Time Factors

2001
Chemical agents that promote chromatin compaction radiosensitize tumour cells.
    International journal of radiation biology, 2001, Volume: 77, Issue:10

    Topics: Alkenes; Cell Survival; Chromatin; Histones; HT29 Cells; Humans; Hydroxamic Acids; Immunohistochemistry; Neoplasms; Okadaic Acid; Polyenes; Pyrones; Radiation Tolerance

2001
Regulation of immunoglobulin E-mediated secretion by protein phosphatases in human basophils and mast cells of skin and lung.
    European journal of pharmacology, 2001, Oct-26, Volume: 430, Issue:1

    Topics: Alkenes; Antifungal Agents; Basophils; Enzyme Inhibitors; Histamine Release; Humans; Immunoglobulin E; Lung; Marine Toxins; Mast Cells; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Polyenes; Pyrans; Pyrones; Skin; Spiro Compounds

2001
P38 mitogen-activated protein kinase dephosphorylation is regulated by protein phosphatase 2A in human platelets activated by collagen.
    FEBS letters, 2002, Sep-25, Volume: 528, Issue:1-3

    Topics: Alkenes; Animals; Blood Platelets; Carrier Proteins; Cattle; Collagen; Enzyme Inhibitors; Humans; In Vitro Techniques; Kinetics; Mitogen-Activated Protein Kinases; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphoprotein Phosphatases; Phosphorylation; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Polyenes; Protein Phosphatase 2; Pyrones

2002
Protein phosphatase 2A enhances activation of human immunodeficiency virus type 1 by phorbol myristate acetate.
    Journal of virology, 2003, Volume: 77, Issue:3

    Topics: Alkenes; HIV-1; Humans; Okadaic Acid; Phosphoprotein Phosphatases; Polyenes; Promoter Regions, Genetic; Protein Kinase C; Protein Phosphatase 2; Pyrones; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells; Virus Activation

2003
Ischemia-induced dephosphorylation of cardiomyocyte connexin-43 is reduced by okadaic acid and calyculin A but not fostriecin.
    Molecular and cellular biochemistry, 2003, Volume: 242, Issue:1-2

    Topics: Alkenes; Animals; Blotting, Western; Cells, Cultured; Connexin 43; Gap Junctions; Gene Expression; Ischemia; Marine Toxins; Myocytes, Cardiac; Okadaic Acid; Oxazoles; Phosphorylation; Polyenes; Pyrones; Rats; Rats, Sprague-Dawley

2003
CRHSP-24 phosphorylation is regulated by multiple signaling pathways in pancreatic acinar cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2003, Volume: 285, Issue:4

    Topics: Alkenes; Animals; Binding Sites; Calcineurin Inhibitors; Calcium; Cholecystokinin; Cyclic AMP; Cyclosporine; DNA-Binding Proteins; Enzyme Inhibitors; Marine Toxins; Okadaic Acid; Oxazoles; Pancreas; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Polyenes; Pyrones; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors

2003
Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A.
    The Journal of biological chemistry, 2005, Oct-28, Volume: 280, Issue:43

    Topics: Active Transport, Cell Nucleus; Adenosine Triphosphate; Alkenes; Animals; B-Lymphocytes; Catalysis; Cell Line; Chromatography, Liquid; Cytoplasm; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Gene Deletion; Humans; I-kappa B Kinase; Immunoblotting; Immunoprecipitation; Inflammation; Jurkat Cells; Mice; Mice, Inbred C57BL; Mutation; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Polyenes; Protein Phosphatase 2; Pyrones; Sepharose; Serine; Signal Transduction; Spleen; Threonine; Time Factors; Transfection; Tumor Necrosis Factor-alpha

2005
Inhibition of PP2A, but not PP5, mediates p53 activation by low levels of okadaic acid in rat liver epithelial cells.
    Journal of cellular biochemistry, 2006, Sep-01, Volume: 99, Issue:1

    Topics: Alkenes; Amino Acid Sequence; Animals; Antigens, Viral, Tumor; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; G1 Phase; Liver; Molecular Sequence Data; Nuclear Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Polyenes; Protein Phosphatase 2; Pyrones; Rats; RNA, Small Interfering; Tumor Suppressor Protein p53

2006
The effects of protein phosphatase inhibitors on the duration of central sensitization of rat dorsal horn neurons following injection of capsaicin.
    Molecular pain, 2006, Jul-17, Volume: 2

    Topics: Afferent Pathways; Alkenes; Animals; Capsaicin; Disease Models, Animal; Enzyme Inhibitors; Inflammation Mediators; Male; Nociceptors; Okadaic Acid; Pain; Pain Threshold; Phosphoprotein Phosphatases; Physical Stimulation; Polyenes; Posterior Horn Cells; Pyrones; Rats; Rats, Sprague-Dawley; Reaction Time; Synaptic Transmission; Time Factors

2006
Okadaic acid overcomes the blocked cell cycle caused by depleting Cdc2-related kinases in Trypanosoma brucei.
    Experimental cell research, 2006, Nov-01, Volume: 312, Issue:18

    Topics: Alkenes; Animals; CDC2 Protein Kinase; Cell Cycle; Enzyme Inhibitors; Humans; Isoenzymes; Okadaic Acid; Phosphoprotein Phosphatases; Polyenes; Protein Phosphatase 2; Protein Subunits; Protozoan Proteins; Pyrones; RNA Interference; Trypanosoma brucei brucei

2006
The chromosomal association of condensin II is regulated by a noncatalytic function of PP2A.
    Nature structural & molecular biology, 2009, Volume: 16, Issue:12

    Topics: Adenosine Triphosphatases; Alkenes; Animals; Cell Line; Cells, Cultured; Chromosomes; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Kinesins; Models, Biological; Multiprotein Complexes; Okadaic Acid; Polyenes; Protein Phosphatase 2; Pyrones; Xenopus

2009