alisol-a-24-acetate and alismol

alisol-a-24-acetate has been researched along with alismol* in 1 studies

Other Studies

1 other study(ies) available for alisol-a-24-acetate and alismol

ArticleYear
[Chemical constituents of Alisma orientalis and their immunosuppressive function].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009, Volume: 34, Issue:8

    To investigate the chemical constituents with immunosuppressive function from Alisma orientalis.. The chemical constituents were isolated and purified by kinds of column chromatography and its structures were elucidated by NMR spectra and physicochemical properties. Its immunocompentence of lymphocytes taken from spleen of mouse were examined by MTT assay.. Twelve compounds were isolated and identified as clovandiol (1), orientalol E (2), alismoxide (3), alismol (4), 4alpha, l0alpha-dihydroxy-5beta-H-guaj-6-en (5), alismorientols A (6), alisol F (7), alisol A (8), 13beta,17beta-epoxy alisol A (9), alisol B 23-acetate (10), 1H-indole-3-carboxylic acid (11) and cuccinic acid (12). Compounds 9, 10 and alisol A 24-acetate showed immunosuppressive function.. Compounds 1, 5, 11 and 12 were isolated firstly from this genus,and the NMR spectra data of 1 were corrected firstly, some protostan-type triterpenoids may be developed as new drug with immunosuppressive function.

    Topics: Alisma; Animals; Cells, Cultured; Cholestenones; Drugs, Chinese Herbal; Immunosuppressive Agents; Indoles; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Sesquiterpenes; T-Lymphocytes; Triterpenes

2009