alendronate has been researched along with simvastatin in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 13 (59.09) | 24.3611 |
| 2020's | 4 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Bowers, JR; Dailiana, ZH; McCarthy, EF; Urbaniak, JR | 1 |
| Bartosová, L; Cermáková, E; Cibicek, N; Cibicková, L; Jun, D; Micuda, S; Palicka, V | 1 |
| Borgström, F; Jönsson, B; Kanis, JA; Ström, O; Zethraeus, N | 1 |
| Chihara, K; Inoue, Y; Kaji, H; Naito, J; Sowa, H; Sugimoto, T | 1 |
| Lee, Y; Liu, X; Marx, DB; Nawshad, A; Reinhardt, RA; Wang, D | 1 |
| Brandt, NJ; Stefanacci, RG | 1 |
| Killeen, AC; Marx, DB; Narayana, N; Payne, JB; Rakes, PA; Reinhardt, RA; Schmid, MJ; Wang, D; Zhang, Y | 1 |
| Le, HO; Marx, DB; Narayana, N; Powell, SE; Price, U; Reinhardt, RA; Schmid, MJ; Wang, D; Zhang, Y | 1 |
| Brannon, M; Chakraborty, K; Kalra, S; Krishnan, K; Lightner, J; Moukharskaya, J; Niyazi, M; Palau, VE; Rogers, M; Stone, WL | 1 |
| Araújo, TS; Carvalho, NS; Costa, DS; Medeiros, JV; Nicolau, LA; Silva, MM; Silva, RO; Soares, PM; Sousa, NA; Souza, LK | 1 |
| Connolly, JG; Gagne, JJ | 1 |
| Abuelezz, SA; Atalla, SS; El Aziz, LFA; Gorge, SS; Mohamed, MT | 1 |
| Gonçalves, RV; Maldonado, IRSC; Novaes, RD; Oliveira, MGA; Oliveira, TT; Pinto, AS; Sequetto, PL | 1 |
| Bettencourt, A; Martin, V | 1 |
| Fervers, F; Henrich, D; Kontradowitz, K; Leiblein, M; Marzi, I; Seebach, C | 1 |
| Bandgar, SA; Jadhav, NR; Manjappa, AS | 1 |
| Apostu, D; Gheban, D; Lucaciu, O; Mester, A; Oltean-Dan, D; Rares Ciprian Benea, H | 1 |
| Chatzopoulos, GS; Koidou, VP; Tsalikis, L | 1 |
3 review(s) available for alendronate and simvastatin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Bone regeneration: Biomaterials as local delivery systems with improved osteoinductive properties.
Topics: Alendronate; Anti-Bacterial Agents; Biocompatible Materials; Blood Platelets; Bone and Bones; Bone Regeneration; Drug Carriers; Humans; Intercellular Signaling Peptides and Proteins; Raloxifene Hydrochloride; Simvastatin | 2018 |
Local drug delivery in the treatment of furcation defects in periodontitis: a systematic review.
Topics: Alendronate; Dental Scaling; Furcation Defects; Humans; Periodontitis; Root Planing; Rosuvastatin Calcium; Simvastatin; Treatment Outcome | 2023 |
19 other study(ies) available for alendronate and simvastatin
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Drug therapy increases bone density in osteonecrosis of the femoral head in canines.
Topics: Alendronate; Animals; Bone Density; Dogs; Femur Head Necrosis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Simvastatin | 2004 |
Differential effects of statins and alendronate on cholinesterases in serum and brain of rats.
Topics: Alendronate; Animals; Atorvastatin; Bone Density Conservation Agents; Brain; Butyrylcholinesterase; Cholinesterases; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Pyrroles; Rats; Rats, Wistar; Simvastatin | 2007 |
The cost-effectiveness of the treatment of high risk women with osteoporosis, hypertension and hyperlipidaemia in Sweden.
Topics: Aged; Aged, 80 and over; Alendronate; Antihypertensive Agents; Bone Density Conservation Agents; Cost-Benefit Analysis; Female; Health Care Costs; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Middle Aged; Models, Econometric; Osteoporosis, Postmenopausal; Quality-Adjusted Life Years; Simvastatin; Sweden | 2008 |
Statin suppresses apoptosis in osteoblastic cells: role of transforming growth factor-beta-Smad3 pathway.
Topics: Alendronate; Animals; Apoptosis; Cell Line; Gene Expression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Osteoblasts; Quinolines; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Simvastatin; Smad3 Protein; Transforming Growth Factor beta | 2008 |
Role of prostaglandin pathway and alendronate-based carriers to enhance statin-induced bone.
Topics: Alendronate; Animals; Cell Line; Cyclodextrins; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intramolecular Oxidoreductases; Mice; Models, Biological; Osteoblasts; Polymerase Chain Reaction; Prostaglandin-E Synthases; Prostaglandins; Rats; Real-Time Polymerase Chain Reaction; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Simvastatin | 2011 |
Discontinuation of unnecessary medications in older adults.
Topics: Aged; Aged, 80 and over; Alendronate; Anti-Ulcer Agents; Antihypertensive Agents; Assisted Living Facilities; Bone Density Conservation Agents; Case Management; Diabetes Mellitus; Drug Therapy; Evidence-Based Medicine; Guidelines as Topic; Hepatitis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Lisinopril; Longevity; Male; Omeprazole; Osteoporosis; Palliative Care; Pharmacists; Precision Medicine; Simvastatin | 2011 |
Impact of local and systemic alendronate on simvastatin-induced new bone around periodontal defects.
Topics: Administration, Topical; Alendronate; Alveolar Bone Loss; Animals; Bone Density Conservation Agents; Bone Regeneration; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections, Intravenous; Mandible; Rats; Rats, Sprague-Dawley; Simvastatin | 2012 |
Effects of local simvastatin-alendronate conjugate in preventing periodontitis bone loss.
Topics: Alendronate; Alveolar Bone Loss; Animals; beta-Cyclodextrins; Bone Density Conservation Agents; Drug Combinations; Endotoxins; Escherichia coli; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imaging, Three-Dimensional; Injections; Lipopolysaccharides; Maxillary Diseases; Molar; Osteoclasts; Palate; Periodontitis; Premedication; Rats; Rats, Sprague-Dawley; Sequestering Agents; Simvastatin; X-Ray Microtomography | 2013 |
Synergistic growth inhibition of PC3 prostate cancer cells with low-dose combinations of simvastatin and alendronate.
Topics: Alendronate; Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Male; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Simvastatin | 2015 |
Protective Effects of Simvastatin Against Alendronate-Induced Gastric Mucosal Injury in Rats.
Topics: Alendronate; Animals; Bone Density Conservation Agents; Dose-Response Relationship, Drug; Female; Gastric Mucosa; Gene Expression Regulation; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-1beta; Malondialdehyde; Peroxidase; Rats; Rats, Wistar; Simvastatin; Stomach Ulcer; Tumor Necrosis Factor-alpha | 2016 |
Comparison of Calipers for Matching on the Disease Risk Score.
Topics: Aged; Aged, 80 and over; Alendronate; Anti-Inflammatory Agents, Non-Steroidal; Bone Density Conservation Agents; Cardiovascular Diseases; Cohort Studies; Computer Simulation; Cyclooxygenase 2 Inhibitors; Epidemiologic Methods; Ezetimibe; Female; Gastrointestinal Hemorrhage; Humans; Male; Medicare; Models, Theoretical; Monte Carlo Method; Odds Ratio; Osteoporotic Fractures; Prognosis; Propensity Score; Raloxifene Hydrochloride; Risk Assessment; Simvastatin; United States | 2016 |
The anti-osteoporotic and anti-atherogenic effects of alendronate and simvastatin in ovariectomized rats fed high fat diet: A comparative study of combination therapy versus monotherapy.
Topics: Alendronate; Alkaline Phosphatase; Animals; Atherosclerosis; Body Weight; Bone and Bones; Bone Density; Combined Modality Therapy; Diet, High-Fat; Female; Osteocalcin; Osteoporosis; Ovariectomy; Rats; Simvastatin | 2017 |
Low Doses of Simvastatin Potentiate the Effect of Sodium Alendronate in Inhibiting Bone Resorption and Restore Microstructural and Mechanical Bone Properties in Glucocorticoid-Induced Osteoporosis.
Topics: Alendronate; Alkaline Phosphatase; Animals; Bone and Bones; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Bone Resorption; Calcium; Dexamethasone; Drug Synergism; Osteoporosis; Phosphorus; Rats; Rats, Wistar; Simvastatin; Urea | 2017 |
Do antiosteoporotic drugs improve bone regeneration in vivo?
Topics: Absorptiometry, Photon; Alendronate; Alkaline Phosphatase; Animals; Biomechanical Phenomena; Blotting, Western; Bone Density; Bone Density Conservation Agents; Bone Morphogenetic Protein 2; Bone Regeneration; Bony Callus; Calcium-Regulating Hormones and Agents; Collagen Type I; Female; Femur; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Macrophage Colony-Stimulating Factor; Osteocalcin; Osteogenesis; Osteogenesis, Distraction; Parathyroid Hormone; Raloxifene Hydrochloride; RANK Ligand; Rats; Reverse Transcriptase Polymerase Chain Reaction; Simvastatin; Thiophenes; Tomography, X-Ray Computed | 2020 |
A remarkable in vitro cytotoxic, cell cycle arresting and proapoptotic characteristics of low-dose mixed micellar simvastatin combined with alendronate sodium.
Topics: Alendronate; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Micelles; Poloxamer; Simvastatin | 2020 |
Tibolone, alendronate, and simvastatin enhance implant osseointegration in a preclinical in vivo model.
Topics: Alendronate; Animals; Bone Density; Dental Implants; Female; Humans; Norpregnenes; Osseointegration; Ovariectomy; Rats; Simvastatin; Titanium | 2020 |