alendronate has been researched along with pamidronate in 168 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 28 (16.67) | 18.2507 |
2000's | 82 (48.81) | 29.6817 |
2010's | 50 (29.76) | 24.3611 |
2020's | 8 (4.76) | 2.80 |
Authors | Studies |
---|---|
Alferiev, IS; Amidon, GL; Breuer, E; Cohen, H; El Hanany-Rozen, N; Ezra, A; Gati, I; Golomb, G; Hoffman, A; Mönkkönen, J; Stepensky, D; Törmälehto, S; Weiss, G | 1 |
Bailey, BN; Docampo, R; Rodriguez, JB; Szajnman, SH | 1 |
Bailey, BN; Caldera, A; Croft, SL; Docampo, R; Grimley, JS; Heath, HT; Kendrick, H; Lewis, JC; Lira, R; Martin, MB; Moreno, SN; Oldfield, E; Urbina, JA; Yardley, V | 1 |
Cieslak, JA; Coates, RM; Fukura, S; Koohang, A; Lea, CR; Lee, HJ; Loftus, TC; Martin, MB; Matsumura, Y; Oldfield, E; Sagami, H; Sanders, JM; Sengupta, S; Szabo, CM | 1 |
Martin, MB; Oldfield, E; Szabo, CM | 1 |
Bachmann, R; Bisping, M; Born, AR; Cortesi, R; Glatt, M; Green, JR; Guiglia, G; Jaeggi, KA; Jeker, H; Klein, R; Müller, K; Ramseier, U; Schmid, J; Schreiber, G; Seltenmeyer, Y; Widler, L | 1 |
Gossman, W; Oldfield, E | 1 |
Burzynska, A; Gómez, AO; González-Pacanowska, D; Kafarski, P; Mao, J; Meints, GA; Oldfield, E; Sanders, JM; Van Brussel, EM | 1 |
Bruchhaus, I; Chan, JM; Croft, SL; Flessner, RM; Ghosh, S; Kemp, RG; Kendrick, H; Kobayashi, S; Lea, CR; Lewis, JC; Loftus, TC; Meints, GA; Nozaki, T; Oldfield, E; Tovian, ZS | 1 |
Burzynska, A; Chan, JM; Colantino, A; Ghosh, S; Kafarski, P; Meints, G; Morita, CT; Oldfield, E; Raker, AM; Sanders, JM; Song, Y; Wang, H | 1 |
Craig, SP; Delfino, JM; Fernández, D; Wenck, MA | 1 |
Chan, JM; Flessner, R; Gómez, AO; González-Pacanowska, D; Jennings, S; Kosztowski, T; Kotsikorou, E; Meints, GA; Morita, CT; Odeh, S; Oldfield, E; Papapoulos, SE; Raker, AM; Sanders, JM; Schwerdtfeger, C; Song, Y; van Beek, ER; Wang, H; Zhang, Y | 1 |
Araujo, FG; Chan, JM; Ling, Y; Moreno, SN; Odeh, S; Oldfield, E; Sahota, G | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Barnett, BL; Dunford, JE; Ebetino, FH; Kavanagh, KL; Kwaasi, AA; Oppermann, U; Rogers, MJ; Russell, RG | 1 |
Axelson, J; Cao, R; Chang, SC; Chang, TH; Guo, RT; Hudock, MP; K-M Chen, C; Ko, TP; Kumar, A; Liang, PH; No, JH; Oldfield, E; Song, Y; Wang, AH; Zhang, Y | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Berlicki, Ł; Kafarski, P; Mucha, A | 1 |
Lecouvey, M; Monteil, M; Puljula, E; Turhanen, P; Vepsäläinen, J; Weisell, J | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Artyushin, OI; Brel, VK; Chuprov-Netochin, RN; Leonov, SV; Semenov, VV; Semenova, MN | 1 |
Almeida Paz, FA; Barbosa, JS; Braga, SS | 1 |
Bauss, F; Bosies, E; Fleisch, H; Janner, M; Mühlbauer, RC; Schenk, R; Strein, K | 1 |
Koiso, K; Miyagawa, I; Nemoto, R; Satou, S | 1 |
Grasser, W; Sato, M | 1 |
Harada, M; Koiso, K; Miyakawa, I; Nemoto, R; Nishijima, Y; Sato, S | 1 |
Warrell, RP | 1 |
Azuma, Y; Kiyoki, M; Ohta, T; Okabe, K; Oue, Y; Sato, H; Tsuchimoto, M | 1 |
Ammann, P; Bonjour, JP; Budayr, AA; Burckhardt, P; Gertz, B; Jaquet-Müller, F; Jenzer, A; Rizzoli, R; Thiébaud, D; Zysset, E | 1 |
Collin, P; Fleisch, H; Guenther, HL; Martin, TJ; Sahni, M | 1 |
Hirvonen, MR; Makkonen, N; Mönkkönen, J; Savolainen, K; Teräväinen, T | 1 |
Chilton, KM; Coxon, FP; Lawry, J; Rogers, MJ; Russell, RG; Smith, MO; Suri, S | 1 |
Licata, AA | 1 |
Body, JJ; Coleman, RE; Piccart, M | 1 |
Adachi, H; Hirafuji, M; Igarashi, K; Mitani, H; Shinoda, H | 1 |
Berman, SK; Blank, MA; Ems, BL; Gibson, GW; Myers, WR; Phipps, RJ; Smith, PN | 1 |
Fleisch, HA | 1 |
Bonde, M; Christiansen, C; Delmas, PD; Fledelius, C; Garnero, P; Qvist, P | 1 |
Hara, N; Nakanishi, Y; Takayama, K | 1 |
Greenwald, RA; Miller, F; Stein, B | 1 |
Alferiev, IS; Breuer, E; Cohen, H; Eidelman, N; Golomb, G; Hägele, G; Ornoy, A; Patlas, N; Solomon, V | 1 |
Azuma, Y; Kanatani, H; Kiyoki, M; Komoriya, K; Ohta, T; Oue, Y | 1 |
Brosch, S; Peterlik, M; Pietschmann, P; Smolen, JS; Steiner, G; Stohlawetz, P | 1 |
Knowles, S; Phillips, E; Shear, NH; Weber, E | 1 |
Den Hartigh, J; Pas, O; Ramp-Koopmanschap, W; Twiss, IM; Vermeij, P | 1 |
Hanemaaijer, R; Heikkilä, P; Konttinen, YT; Laitinen, M; Maisi, P; Salo, T; Sorsa, T; Teronen, A; Teronen, O | 1 |
Alferiev, IS; Breuer, E; Cohen, H; Ezra, A; Golomb, G; Hägele, G; Hoffman, A; Mönkkönen, J; Ornoy, A; Patlas, N; Pinto, T; Sagi, H; Seibel, MJ; Solomon, V; Stepensky, D | 1 |
Bhagat, CI; Criddle, A; Faulkner, DL; Gan, SK; Geelhoed, E; Gutteridge, DH; Kent, GN; Price, RI; Prince, RL; Retallack, RW; Stewart, GO; Stuckey, BG; Vasikaran, S; Ward, LC; Will, RK | 1 |
Bellido, T; Manolagas, SC; Parfitt, AM; Plotkin, LI; Roberson, PK; Weinstein, RS | 1 |
Bastaki, S; Blank, MA; Dicay, M; McKnight, W; Wallace, JL | 1 |
Berenson, J; Hortobagyi, G; Lipton, A; Major, PP | 1 |
Bergstrom, JD; Bostedor, RG; Masarachia, PJ; Reszka, AA; Rodan, G | 1 |
Daley, J; Hartman, EE | 1 |
Adami, S; Braga, V; Fracassi, E; Gatti, D; Gerardi, D; Guidi, G | 1 |
Bauer, E; Feurle, J; Kunzmann, V; Tony, HP; Weissinger, F; Wilhelm, M | 1 |
Blank, MA; Dierckman, TA; Gibson, GW; Myers, WR; Phipps, RJ; Smith, PN | 1 |
Ball, DW; Basaria, S; Belzberg, AJ; McCarthy, EF | 1 |
Blank, MA; Gibson, GW; Lichtenberger, LM; Romero, JJ | 1 |
Papapoulos, SE | 1 |
Brand, J; Curtin, J; Hommen, JP; Khan, SN; Lane, JM; Nydick, M; O'Connor, WJ; Schneider, R; Tomin, E | 1 |
Watts, NB | 1 |
Bukowski, JF; Das, H; Kamath, A; Wang, L | 1 |
Gutteridge, DH; Kent, GN; Lim, EM; Stuckey, BG; Ward, LC | 1 |
Cahill, BC; Karwande, SV; Knecht, TP; O'Rourke, MK; Parker, S; Stringham, JC | 1 |
Gomez-Acotto, C; Mautalen, C; Zeni, S | 1 |
Chandia, M; Costa, MC; Costa, MR; Fausto, R; Gano, L; Neves, M; Pereira, N; Rosado, M | 1 |
Jeong-Hwa, B; Kim, GS; Kim, YH | 1 |
Heijckmann, AC; Juttmann, JR; Wolffenbuttel, BH | 1 |
Bergmann, P; Body, JJ; Dumon, JC; Fellemans, C; Fuss, M; Peretz, A; Rozenberg, S; Siderova, V | 1 |
Kotsikorou, E; Oldfield, E | 1 |
Epstein, M; Joshua, F; Major, G | 1 |
Cheng, YY; Huang, L; Kumta, SM; Lee, KM; Xu, JK; Zheng, MH | 1 |
Bhagat, CI; Criddle, RA; Dhaliwal, SS; Drury, PJ; Gutteridge, DH; Kent, GN; Prince, RL; Retallack, RW; Stewart, GO; Stuckey, BG; Vasikaran, S; Walsh, JP; Ward, LC; Will, RK | 1 |
Gharib, S | 1 |
Boos, J; Lanvers-Kaminsky, C; Vorotnjak, M | 1 |
Dimeglio, LA; Ford, L; McClintock, C; Peacock, M | 1 |
Abrahamsen, B; Brixen, KT; Kassem, MS; Mosekilde, L | 1 |
Carter, G; Doecke, C; Goss, AN | 1 |
Bultink, IE; Dijkmans, BA; Lems, WF; Vis, M | 1 |
Cortizo, AM; McCarthy, AD; Vaisman, DN | 1 |
Azzarello, G; Balducci, E; Crepaldi, G; Dalle Carbonare, L; Giannini, S; Realdi, G; Valenti, MT; Vinante, O | 1 |
Hande, K; Richardson, PG; Woo, SB | 1 |
Kwon, KI; Yun, MH | 1 |
Bourgeois, SL; Goodell, GG; Sarathy, AP | 1 |
Broumand, V; Fortin, M; Marx, RE; Sawatari, Y | 1 |
DiMeglio, LA; Peacock, M | 1 |
Eufinger, H; Hoefert, S | 1 |
Robb-Nicholson, C | 1 |
Bosch, JJ; Burggraaf, J; Cohen, AF; de Kam, ML; Twiss, IM; van den Berk, AH; Vermeij, P | 1 |
Alexander, RE | 1 |
Franke, HR; Verdijk, R; Vermes, I; Wolbers, F | 1 |
Anderson, EI; Bexheti, D; Hanna-Brown, M; Hutt, AJ | 1 |
Langdahl, B; Mosekilde, L; Vestergaard, P | 1 |
Alati, C; Allegra, A; Alonci, A; Cicciù, M; De Ponte, FS; Musolino, C; Nastro, E; Oteri, G; Quartarone, E | 1 |
Bonaninil, M; Corcione, L; Corradi, D; D'Aleo, P; Ferrari, S; Guidotti, R; Manfredi, M; Meleti, M; Merigo, E; Poli, T; Ripasarti, A; Sesenna, E; Vescovi, P; Zanzucchi, E | 1 |
Azzarello, G; Balducci, E; Bertoldo, F; Dalle Carbonare, L; Fracalossi, A; Lo Cascio, V; Valenti, MT; Vinante, O | 1 |
Ji, T; Ruan, M; Zhang, CP | 1 |
Dulea, C; Gherase, A; Savu, SR; Silvestro, L; Tarcomnicu, I | 1 |
Mukherjee, S; Oldfield, E; Song, Y | 1 |
Damiani, D | 1 |
Bianchi, ML; Biggioggero, M; Frasunkiewicz, J; Limonta, C; Vai, S | 1 |
Greig, IR; Idris, AI; Ralston, SH; Rojas, J; Van't Hof, RJ | 1 |
Chagin, AS; Heino, TJ; Sävendahl, L; Takigawa, M | 1 |
French, DD; Margo, CE | 1 |
Goepferich, A; Mayr, H; Schuessele, A; Tessmar, J | 1 |
Silverman, SL | 1 |
Arnol, V; Cortizo, AM; Felice, JI; Gangoiti, MV; McCarthy, AD | 1 |
Bigi, A; Bracci, B; Fini, M; Panzavolta, S; Torricelli, P | 1 |
Yamashita, S | 2 |
Choi, D; Fraunfelder, FT; Fraunfelder, FW; Suhler, E; Winthrop, K | 1 |
Geusens, P | 1 |
Elad, S; Hardan, I; Lazarovici, TS; Taicher, S; Yahalom, R; Yarom, N | 1 |
Christou, S; Efstathiou, E; Ioannou, YS; Kyriakou, A; Savva, SC; Savvides, I; Skordis, N | 1 |
Balasanian, E; Stanton, DC | 1 |
Baer, D; Han, MM; Hui, RL; Khoury, S; Liao, W; Liberty, D; Lo, JC; Martin, D; O'Ryan, FS | 1 |
Eufinger, H; Hoefert, S; Schmitz, I; Tannapfel, A | 1 |
Lamprecht, G | 1 |
Carter, T; Cole, C; Kotecha, RS; Lee, SJ; Murray, KJ; Powers, N | 1 |
Endo, Y; Funayama, H; Kawamura, H; Kumamoto, H; Kuroishi, T; Oizumi, T; Sasaki, K; Sugawara, S; Takahashi, H; Yamaguchi, K; Yamamoto, M; Yokoyama, M | 1 |
Henry, C; Jahnke, W | 1 |
Friedland, B; Treister, NS; Woo, SB | 1 |
Friedrich, NF; Graf, C; Kraenzlin, C; Kraenzlin, ME; Meier, C | 1 |
Arduino, PG; Broccoletti, R; Dalmasso, P; Mozzati, M; Scoletta, M | 1 |
Gillen, C; Nunes, M; Shapiro, JR; Thompson, CB; Wu, Y | 1 |
Byard, S; Duer, MJ; Ironside, MS; Reid, DG | 1 |
Darmon, P; Molines, L; Raccah, D | 1 |
Dabbous, MKh; Seshul, BA; Tipton, DA | 1 |
Kwon, SR; Lim, MJ; Park, SG; Park, W | 1 |
Hussein, O; Komarova, SV; Tiedemann, K | 1 |
Barrs, VR; Beatty, JA; Briscoe, KA; Whitney, JL; Wilkinson, MR | 1 |
Correia, JD; Gano, L; Oliveira, BL; Palma, E; Santos, I; Santos, IC | 1 |
Alloh Amichia, YC; Giumelli, B; Le Bars, P; Soueidan, A | 1 |
Goltz, D; Jauch, C; Schott, H; Schott, TC; Schwendener, RA | 1 |
Kwon, YD; Lee, HW; Ohe, JY | 1 |
Bartl, R | 1 |
Marchetti, C; Montebugnoli, L; Moretti, F; Pelliccioni, GA | 1 |
Alasti, M; Beladi Mousavi, SS; Ghorbani, A; Omidvar, B; Shahbazian, H; Shariat Nabavi, SJ | 1 |
Açil, Y; Gassling, V; Möller, B; Niehoff, P; Rachko, K; Simon, MJ; Wiltfang, J | 1 |
Boulman, N; Kaly, L; Rimar, D; Rosner, I; Rozenbaum, M; Slobodin, G | 1 |
Carson, DA; Cho, JS; Corr, M; Crain, B; Hayashi, T; Miller, LS; Norton, JT | 1 |
Grätz, KW; Jacobsen, C; Metzler, P; Obwegeser, J; Rössle, M; Zemann, W | 1 |
Freiberger, JJ; Kraft, KH; McGraw, T; Moon, RE; Padilla-Burgos, R; Piantadosi, CA; Stolp, BW; Suliman, HB | 1 |
Chen, M; Chen, Y; Chen, Z; Liu, Y; Zhu, Y | 1 |
Abbas, FM; Behnia, H; Dashti, SG; Dehghan, MM; Khojasteh, A; Morad, G; Shahab, S | 1 |
Afsie, S; Al-Nammari, SS; Timothy, T | 1 |
Bouxsein, ML; Brooks, DJ; Demay, MB; Louis, L; Zhu, ED | 1 |
Chikazu, D; Hamada, H; Koizumi, T; Matsuo, A; Satomi, T | 1 |
Bohgaki, M; Goto, M; Imoto, S; Matsumoto, E; Saigo, K | 1 |
De Luna-Bertos, E; García-Martínez, O; Manzano-Moreno, FJ; Ramos-Torrecillas, J; Ruiz, C | 1 |
Araz, K; Dagdeviren, A; Helvacioglu, F; Sahin, F; Senel, FV; Soydan, SS; Tekindal, MA; Yurtcu, E | 1 |
Beecham, E; Bluebond-Langner, M; Candy, B; Howard, R; Jones, L; Laddie, J; McCulloch, R; Rees, H; Vickerstaff, V | 1 |
Bhethanabotla, VR; Conners, CM; Gupta, VK | 1 |
Cunneen, TS; Goold, LA; Leibovitch, I; Martin, P; Pirbhai, A; Rajak, SN; Selva, D; Wilcsek, G | 1 |
Amin, NL; James, RM; Phillips, R | 1 |
Mészaros, Á; Veszelyné Kotán, E | 2 |
González, R; López-Posadas, R; Martínez-Augustin, O; Mascaraque, C; Sánchez de Medina, F; Suárez, MD; Zarzuelo, A | 1 |
Casasnovas, R; Fernández, D; Frau, J; Ortega-Castro, J; Ramis, R; Vilanova, B | 1 |
Filella, X; Florez, H; Guañabens, N; Mandelikova, S; Monegal, A; Peris, P | 1 |
Dehghan, MM; Khojasteh, A; Nazeman, P | 1 |
Chowdhury, A; Karamched, SR; Nosoudi, N; Parasaram, V; Parrish, J; Siclari, S | 1 |
Hanioka, Y; Harada, D; Izui, M; Kashiwagi, H; Kishimoto, K; Kondo, K; Nagamatsu, Y; Namba, N; Oriyama, K; Sakamoto, N; Seino, Y; Tanaka, H; Ueyama, K; Yamada, H | 1 |
Adams, A; Heidenreich, A; Jakob, T; Kuhr, K; Macherey, S; Monsef, I; Skoetz, N; Tesfamariam, YM | 1 |
Chworos, A; Gostynski, B; Madaj, R; Pawlowska, R | 1 |
Chang, AB; Conwell, LS; Jeffery, TC | 1 |
Bhardwaj, A; Sinha, NK; Swe, KMM | 1 |
Chen, Y; Huang, Y; Xiao, Y | 1 |
26 review(s) available for alendronate and pamidronate
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Bisphosphonates, Old Friends of Bones and New Trends in Clinics.
Topics: Animals; Bone and Bones; Bone Density Conservation Agents; Bone Diseases; Diphosphonates; Drug Compounding; Drug Delivery Systems; Humans | 2021 |
Hypercalcemia and bone metastases in breast cancer.
Topics: Alendronate; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Hypercalcemia; Neoplasm Proteins; Pamidronate; Parathyroid Hormone-Related Protein; Proteins; Transforming Growth Factors | 1990 |
Bisphosphonate therapy.
Topics: Alendronate; Animals; Bone Density; Bone Resorption; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Fractures, Bone; Humans; Osteoclasts; Osteoporosis; Osteoporosis, Postmenopausal; Pamidronate; Risedronic Acid | 1997 |
Use of bisphosphonates in cancer patients.
Topics: Alendronate; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Multiple Myeloma; Osteolysis; Pain; Pamidronate; Structure-Activity Relationship | 1996 |
Bisphosphonates: preclinical aspects and use in osteoporosis.
Topics: Alendronate; Animals; Bone Resorption; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Osteoporosis; Pamidronate | 1997 |
[Paraneoplastic syndrome].
Topics: Alendronate; Anticoagulants; Cushing Syndrome; Diagnosis, Differential; Diphosphonates; Disseminated Intravascular Coagulation; Diuretics; Furosemide; Heparin; Humans; Hypercalcemia; Inappropriate ADH Syndrome; Lung Neoplasms; Pamidronate; Paraneoplastic Syndromes | 1997 |
Oral bisphosphonates: A review of clinical use in patients with bone metastases.
Topics: Alendronate; Biological Availability; Bone Density; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Clodronic Acid; Diphosphonates; Double-Blind Method; Etidronic Acid; Humans; Ibandronic Acid; Imidazoles; Male; Multiple Myeloma; Pamidronate; Prostatic Neoplasms; Pyridines; Randomized Controlled Trials as Topic; Risedronic Acid; Zoledronic Acid | 2000 |
Bisphosphonates in the treatment of osteoporosis. Principles and efficacy.
Topics: Administration, Oral; Alendronate; Animals; Bone and Bones; Bone Density; Calcium Channel Blockers; Controlled Clinical Trials as Topic; Diphosphonates; Etidronic Acid; Female; Hip Fractures; Humans; Middle Aged; Osteoporosis; Osteoporosis, Postmenopausal; Pamidronate; Papio; Prospective Studies; Randomized Controlled Trials as Topic; Risedronic Acid; Spinal Fractures; Time Factors | 2000 |
Treatment of osteoporosis with bisphosphonates.
Topics: Aged; Alendronate; Bone and Bones; Bone Density; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Fractures, Bone; Humans; Middle Aged; Osteoporosis, Postmenopausal; Pamidronate; Risedronic Acid | 2001 |
[Pharmacological treatment of osteitis deformans (Paget's bone disease)].
Topics: Alendronate; Analgesics, Non-Narcotic; Antimetabolites; Calcitonin; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Osteitis Deformans; Pamidronate; Radionuclide Imaging; Risedronic Acid | 2005 |
Fracture prevention in postmenopausal women.
Topics: Aged; Alendronate; Bone Density Conservation Agents; Calcitonin; Calcium; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Fractures, Spontaneous; Hormone Replacement Therapy; Humans; Ibandronic Acid; Osteoporosis, Postmenopausal; Pamidronate; Parathyroid Hormone; Risedronic Acid; Selective Estrogen Receptor Modulators; Vitamin D | 2006 |
Paget disease of bone: therapeutic options.
Topics: Alendronate; Alkaline Phosphatase; Anti-Inflammatory Agents; Diphosphonates; Etidronic Acid; Humans; Osteitis Deformans; Pamidronate; Retreatment; Risedronic Acid; Treatment Outcome | 2008 |
[Bisphosphonates and other new therapeutic agents for the treatmednt of osteogenesis imperfecta].
Topics: Alendronate; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bone Density Conservation Agents; Child, Preschool; Clinical Trials as Topic; Denosumab; Diphosphonates; Drug Administration Schedule; Genetic Therapy; Humans; Imidazoles; Infusions, Intravenous; Osteogenesis Imperfecta; Pamidronate; RANK Ligand; Severity of Illness Index; Stem Cell Transplantation; Teriparatide; Zoledronic Acid | 2009 |
Bisphosphonates for postmenopausal osteoporosis: determining duration of treatment.
Topics: Alendronate; Animals; Bone Density Conservation Agents; Diphosphonates; Etidronic Acid; Female; Fracture Healing; Fractures, Bone; Humans; Jaw Diseases; Middle Aged; Osteonecrosis; Osteoporosis, Postmenopausal; Pamidronate; Risedronic Acid | 2009 |
[Bone and joint diseases in children. Bisphosphonates in osteogenesis imperfecta].
Topics: Administration, Oral; Alendronate; Bone Density Conservation Agents; Child; Child, Preschool; Diphosphonates; Humans; Imidazoles; Infant; Infusions, Intravenous; Osteogenesis Imperfecta; Pamidronate; Severity of Illness Index; Zoledronic Acid | 2010 |
Charcot's foot: newest findings on its pathophysiology, diagnosis and treatment.
Topics: Alendronate; Arthropathy, Neurogenic; Biomarkers; Bone Density Conservation Agents; Calcitonin; Diabetic Foot; Diagnosis, Differential; Diphosphonates; Early Diagnosis; Foot Deformities, Acquired; Foot Injuries; Humans; Osteoprotegerin; Pamidronate; Randomized Controlled Trials as Topic; RANK Ligand; Weight-Bearing | 2010 |
A Surgeon's guide to advances in the pharmacological management of acute Charcot neuroarthropathy.
Topics: Alendronate; Alkaline Phosphatase; Arthropathy, Neurogenic; Bone Density Conservation Agents; Calcitonin; Diphosphonates; Humans; Hydroxyproline; Imidazoles; Immobilization; Insulin-Like Growth Factor I; Pamidronate; Randomized Controlled Trials as Topic; RANK Ligand; Skin Temperature; Zoledronic Acid | 2013 |
Pharmacological interventions for pain in children and adolescents with life-limiting conditions.
Topics: Adolescent; Alendronate; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Child; Child, Preschool; Diphosphonates; Gastrointestinal Diseases; Humans; Injections, Spinal; Neuromuscular Agents; Osteogenesis Imperfecta; Pain; Pamidronate; Seizures; Young Adult | 2015 |
Bisphosphonate-Induced Orbital Inflammation: A Case Series and Review.
Topics: Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Bone Diseases, Metabolic; Diphosphonates; Female; Humans; Imidazoles; Male; Middle Aged; Orbital Cellulitis; Orbital Myositis; Pamidronate; Radiography; Retrospective Studies; Zoledronic Acid | 2015 |
QUESTION 1: Should we be using bisphosphonates for osteonecrosis complicating childhood acute lymphoblastic leukaemia?
Topics: Adolescent; Alendronate; Antineoplastic Agents; Bone Density Conservation Agents; Diphosphonates; Female; Humans; Osteonecrosis; Pain; Pamidronate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risedronic Acid | 2016 |
[Therapeutic practice of bisphosphonate use and related pharmaceutical issues I].
Topics: Alendronate; Bone Density Conservation Agents; Bone Diseases, Metabolic; Bone Neoplasms; Clodronic Acid; Diphosphonates; Fractures, Bone; Humans; Hungary; Ibandronic Acid; Imidazoles; Osteoporosis; Pamidronate; Risedronic Acid; Zoledronic Acid | 2016 |
Bisphosphosphonate-calcium phosphate cement composite and its properties.
Topics: Alendronate; Animals; Biocompatible Materials; Bone Density Conservation Agents; Calcium Phosphates; Diphosphonates; Drug Carriers; Drug Delivery Systems; Etidronic Acid; Humans; Pamidronate; Zoledronic Acid | 2019 |
Bisphosphonates or RANK-ligand-inhibitors for men with prostate cancer and bone metastases: a network meta-analysis.
Topics: Adult; Alendronate; Antineoplastic Agents, Hormonal; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Bone Neoplasms; Clodronic Acid; Denosumab; Diphosphonates; Etidronic Acid; Humans; Male; Network Meta-Analysis; Pamidronate; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Quality of Life; Randomized Controlled Trials as Topic; RANK Ligand; Risedronic Acid; Zoledronic Acid | 2020 |
Bisphosphonates for osteoporosis in people with cystic fibrosis.
Topics: Adult; Alendronate; Bone Density Conservation Agents; Child; Cystic Fibrosis; Diphosphonates; Female; Fractures, Bone; Humans; Musculoskeletal Pain; Osteoporosis; Pamidronate; Quality of Life; Randomized Controlled Trials as Topic; Spinal Fractures; Zoledronic Acid | 2023 |
Treatment for osteoporosis in people with beta-thalassaemia.
Topics: Adult; Alendronate; beta-Thalassemia; Child; Clodronic Acid; Denosumab; Diphosphonates; Female; Fractures, Bone; Humans; Male; Middle Aged; Osteoporosis; Pamidronate | 2023 |
17 trial(s) available for alendronate and pamidronate
Article | Year |
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Hypercalcemia and bone metastases in breast cancer.
Topics: Alendronate; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Hypercalcemia; Neoplasm Proteins; Pamidronate; Parathyroid Hormone-Related Protein; Proteins; Transforming Growth Factors | 1990 |
Paget's disease: acquired resistance to one aminobisphosphonate with retained response to another.
Topics: Aged; Alendronate; Diphosphonates; Drug Resistance; Female; Humans; Male; Osteitis Deformans; Pamidronate | 1999 |
Chronic intravenous aminobisphosphonate therapy increases high-density lipoprotein cholesterol and decreases low-density lipoprotein cholesterol.
Topics: Alendronate; Alkaline Phosphatase; Amino Acids; Apolipoprotein A-I; Apolipoproteins B; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diphosphonates; Female; Humans; Infusions, Intravenous; Isoenzymes; Osteoporosis, Postmenopausal; Pamidronate; Structure-Activity Relationship; Triglycerides | 2000 |
Prevention of bone loss and fracture after lung transplantation: a pilot study.
Topics: Absorptiometry, Photon; Adult; Alendronate; Bone Density; Diphosphonates; Drug Administration Schedule; Female; Fractures, Bone; Humans; Lumbar Vertebrae; Lung Transplantation; Male; Middle Aged; Osteoporosis; Pamidronate; Preoperative Care; Prospective Studies; Treatment Outcome | 2001 |
Response to alendronate in osteoporotic women previously treated with pamidronate.
Topics: Administration, Oral; Aged; Alendronate; Alkaline Phosphatase; Bone Density; Calcium; Collagen; Dietary Supplements; Diphosphonates; Female; Hip; Humans; Injections, Intravenous; Lumbar Vertebrae; Osteoporosis, Postmenopausal; Pamidronate; Prospective Studies; Treatment Outcome; Vitamin D | 2003 |
Bisphosphonate resistance in Paget's disease of bone.
Topics: Aged; Aged, 80 and over; Alendronate; Alkaline Phosphatase; Anti-Inflammatory Agents; Clodronic Acid; Diphosphonates; Drug Resistance; Humans; Injections, Intravenous; Middle Aged; Osteitis Deformans; Pamidronate | 2003 |
A randomized clinical trial comparing oral alendronate and intravenous pamidronate for the treatment of Paget's disease of bone.
Topics: Administration, Oral; Aged; Alendronate; Alkaline Phosphatase; Biomarkers; Bone and Bones; Calcium; Diphosphonates; Female; Humans; Injections, Intravenous; Male; Osteitis Deformans; Pain; Pamidronate; Quality of Life | 2004 |
A comparison of oral and intravenous bisphosphonate therapy for children with osteogenesis imperfecta.
Topics: Administration, Oral; Adolescent; Age Factors; Alendronate; Anti-Inflammatory Agents; Bone Density; Child; Child Development; Child, Preschool; Diphosphonates; Female; Humans; Infusions, Intravenous; Male; Osteogenesis Imperfecta; Pamidronate; Prospective Studies; Severity of Illness Index; Treatment Outcome | 2005 |
Two-year clinical trial of oral alendronate versus intravenous pamidronate in children with osteogenesis imperfecta.
Topics: Administration, Oral; Alendronate; Biomarkers; Bone Density Conservation Agents; Bone Remodeling; Child; Diphosphonates; Female; Fractures, Bone; Humans; Incidence; Injections, Intravenous; Male; Osteogenesis Imperfecta; Pamidronate; Prospective Studies | 2006 |
A comparison of the gastrointestinal effects of the nitrogen-containing bisphosphonates pamidronate, alendronate, and olpadronate in humans.
Topics: Adult; Alendronate; Bone Density Conservation Agents; Cross-Over Studies; Diphosphonates; Female; Gastrointestinal Diseases; Humans; Pamidronate; Single-Blind Method | 2006 |
Effect of bisphosphonate treatment on bone mineral density in patients with thalassaemia major.
Topics: Absorptiometry, Photon; Adult; Alendronate; beta-Thalassemia; Bone Density; Bone Density Conservation Agents; Diphosphonates; Female; Humans; Male; Middle Aged; Osteoporosis; Pamidronate; Retrospective Studies; Young Adult | 2008 |
Use of bisphosphonates for the treatment of osteonecrosis as a complication of therapy for childhood acute lymphoblastic leukaemia (ALL).
Topics: Administration, Oral; Adolescent; Adrenal Cortex Hormones; Alendronate; Antineoplastic Combined Chemotherapy Protocols; Calcium; Child; Child, Preschool; Combined Modality Therapy; Diphosphonates; Female; Humans; Incidence; Infusions, Intravenous; Male; Osteonecrosis; Pain; Pamidronate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy; Risk Factors; Vitamin D | 2010 |
Bone mineral density and fracture rate in response to intravenous and oral bisphosphonates in adult osteogenesis imperfecta.
Topics: Administration, Oral; Adult; Alendronate; Bone Density; Bone Density Conservation Agents; Cohort Studies; Diphosphonates; Female; Fractures, Bone; Humans; Injections, Intravenous; Male; Osteogenesis Imperfecta; Pamidronate; Retrospective Studies; Treatment Outcome | 2010 |
A prospective clinical trial for assessing the efficacy of a minimally invasive protocol in patients with bisphosphonate-associated osteonecrosis of the jaws.
Topics: Aged; Aged, 80 and over; Alendronate; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Chlorhexidine; Diphosphonates; Drug Combinations; Female; Follow-Up Studies; Humans; Imidazoles; Male; Metronidazole; Middle Aged; Mouthwashes; Oral Hygiene; Pain Measurement; Pamidronate; Prospective Studies; Salicylates; Terpenes; Treatment Outcome; Zoledronic Acid | 2011 |
Comparison of alendronate and pamidronate on bone loss in kidney transplant patients for the first 6 months of transplantation.
Topics: Absorptiometry, Photon; Administration, Oral; Adult; Alendronate; Anti-Inflammatory Agents; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Diphosphonates; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Injections, Intravenous; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Pamidronate; Time Factors; Treatment Outcome; Young Adult | 2011 |
What is the role of hyperbaric oxygen in the management of bisphosphonate-related osteonecrosis of the jaw: a randomized controlled trial of hyperbaric oxygen as an adjunct to surgery and antibiotics.
Topics: Aged; Alendronate; Anti-Bacterial Agents; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Breast Neoplasms; Combined Modality Therapy; Debridement; Diphosphonates; Female; Follow-Up Studies; Gingiva; Humans; Hyperbaric Oxygenation; Imidazoles; Male; Multiple Myeloma; Osteoporosis; Pain Management; Pamidronate; Prospective Studies; Quality of Life; Treatment Outcome; Wound Healing; Zoledronic Acid | 2012 |
Monthly intravenous alendronate treatment can maintain bone strength in osteogenesis imperfecta patients following cyclical pamidronate treatment.
Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Equivalence Trials as Topic; Female; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Japan; Maintenance Chemotherapy; Male; Osteogenesis Imperfecta; Pamidronate; Treatment Outcome | 2020 |
126 other study(ies) available for alendronate and pamidronate
Article | Year |
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A peptide prodrug approach for improving bisphosphonate oral absorption.
Topics: Administration, Oral; Alendronate; Animals; Biological Availability; Caco-2 Cells; Carrier Proteins; Chemical Precipitation; Dipeptides; Diphosphonates; Durapatite; Humans; Injections, Intravenous; Intestinal Absorption; Pamidronate; Peptide Transporter 1; Prodrugs; Rats; Symporters; Tissue Distribution | 2000 |
Bisphosphonates derived from fatty acids are potent growth inhibitors of Trypanosoma cruzi.
Topics: Animals; Bone Resorption; Diphosphonates; Fatty Acids; Humans; Inhibitory Concentration 50; Parasitic Sensitivity Tests; Trypanocidal Agents; Trypanosoma cruzi; United States; United States Food and Drug Administration | 2001 |
Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapy.
Topics: Animals; Antiprotozoal Agents; Chlorocebus aethiops; Diphosphonates; Leishmania donovani; Plasmodium falciparum; Structure-Activity Relationship; Toxoplasma; Trypanosoma brucei brucei; Trypanosoma cruzi; Vero Cells | 2001 |
Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates and diphosphates: a potential route to new bone antiresorption and antiparasitic agents.
Topics: Alkyl and Aryl Transferases; Antiparasitic Agents; Bone Resorption; Diphosphonates; Enzyme Inhibitors; Farnesyltranstransferase; Humans; Models, Molecular; Organophosphates; Quantitative Structure-Activity Relationship; Recombinant Proteins | 2002 |
An investigation of bone resorption and Dictyostelium discoideum growth inhibition by bisphosphonate drugs.
Topics: Alkyl and Aryl Transferases; Animals; Bone Resorption; Crystallography, X-Ray; Dictyostelium; Diphosphonates; Enzyme Inhibitors; Geranyltranstransferase; Humans; Inhibitory Concentration 50; Models, Molecular; Quantitative Structure-Activity Relationship; Rats | 2002 |
Highly potent geminal bisphosphonates. From pamidronate disodium (Aredia) to zoledronic acid (Zometa).
Topics: Animals; Bone Resorption; Calcitriol; Diphosphonates; Hypercalcemia; Imidazoles; In Vitro Techniques; Kidney; Mice; Pamidronate; Parathyroidectomy; Rats; Skull; Structure-Activity Relationship; Thyroidectomy; Zoledronic Acid | 2002 |
Quantitative structure--activity relations for gammadelta T cell activation by phosphoantigens.
Topics: Antigens, Bacterial; Lymphocyte Activation; Models, Molecular; Phosphoproteins; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocytes | 2002 |
3-D QSAR investigations of the inhibition of Leishmania major farnesyl pyrophosphate synthase by bisphosphonates.
Topics: Animals; Crystallography, X-Ray; Dimethylallyltranstransferase; Diphosphonates; Imidazoles; Leishmania major; Models, Molecular; Picolinic Acids; Pyridines; Quantitative Structure-Activity Relationship; Zoledronic Acid | 2003 |
Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo.
Topics: Animals; Antimalarials; Antiprotozoal Agents; Cell Line; Cricetinae; Diphosphonates; Entamoeba histolytica; Entamoebiasis; Humans; In Vitro Techniques; Liver Abscess; Malaria; Mice; Mice, Inbred BALB C; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship | 2004 |
Quantitative structure-activity relationships for gammadelta T cell activation by bisphosphonates.
Topics: Alkyl and Aryl Transferases; Animals; Cell Division; Cell Line; Diphosphonates; Geranyltranstransferase; Humans; Leishmania major; Lymphocyte Activation; Models, Molecular; Quantitative Structure-Activity Relationship; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocytes; Tumor Necrosis Factor-alpha | 2004 |
The purine transferase from Trypanosoma cruzi as a potential target for bisphosphonate-based chemotherapeutic compounds.
Topics: Animals; Diphosphonates; Drug Delivery Systems; Pentosyltransferases; Trypanosoma cruzi | 2004 |
Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorption.
Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Bone Resorption; Calcium; Dictyostelium; Diphosphonates; Geranyltranstransferase; Humans; In Vitro Techniques; Leishmania major; Metatarsal Bones; Mice; Models, Molecular; Pyridinium Compounds; Quantitative Structure-Activity Relationship; Receptors, Antigen, T-Cell, gamma-delta; Trypanocidal Agents | 2005 |
Bisphosphonate inhibitors of Toxoplasma gondi growth: in vitro, QSAR, and in vivo investigations.
Topics: Aldose-Ketose Isomerases; Alkyl and Aryl Transferases; Animals; Antiprotozoal Agents; Cell Line; Diphosphonates; Fosfomycin; Geranyltranstransferase; Humans; Mice; Models, Molecular; Multienzyme Complexes; Oxidoreductases; Quantitative Structure-Activity Relationship; Toxoplasma; Toxoplasmosis | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Structure-activity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of human farnesyl pyrophosphate synthase.
Topics: Binding Sites; Diphosphonates; Enzyme Inhibitors; Geranyltranstransferase; Humans; Models, Molecular; Molecular Structure; Nitrogen; Stereoisomerism; Structure-Activity Relationship; Time Factors | 2008 |
Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation.
Topics: Antineoplastic Agents; Crystallography, X-Ray; Diphosphonates; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Farnesyltranstransferase; Humans; K562 Cells; Magnetic Resonance Spectroscopy; Models, Molecular; Quantitative Structure-Activity Relationship | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Remarkable potential of the α-aminophosphonate/phosphinate structural motif in medicinal chemistry.
Topics: Amino Acid Motifs; Chemistry, Pharmaceutical; Humans; Organophosphonates; Phosphinic Acids | 2011 |
Structural requirements for bisphosphonate binding on hydroxyapatite: NMR study of bisphosphonate partial esters.
Topics: | 2015 |
Synthesis and biological evaluation of indolylglyoxylamide bisphosphonates, antimitotic microtubule-targeting derivatives of indibulin with improved aqueous solubility.
Topics: Acetamides; Animals; Antimitotic Agents; Cell Line, Tumor; Diphosphonates; Drug Screening Assays, Antitumor; Embryo, Nonmammalian; Humans; Indoles; Sea Urchins; Solubility | 2020 |
BM 21.0955, a potent new bisphosphonate to inhibit bone resorption.
Topics: Alendronate; Animals; Benzoates; Bone Resorption; Calcium; Clodronic Acid; Diphosphonates; Etidronic Acid; Ibandronic Acid; Injections, Intravenous; Osteoclasts; Pamidronate; Rats; Retinoids; Risedronic Acid; Spectrophotometry, Atomic; Tetracycline; Thyroxine | 1991 |
Inhibition by a new bisphosphonate (AHBuBP) of bone resorption induced by the MBT-2 tumor of mice.
Topics: Alendronate; Animals; Diphosphonates; Etidronic Acid; Female; Mice; Mice, Inbred C3H; Necrosis; Neoplasm Transplantation; Osteolysis; Pamidronate; Radiography; Skull; Urinary Bladder Neoplasms | 1991 |
Effects of bisphosphonates on isolated rat osteoclasts as examined by reflected light microscopy.
Topics: Alendronate; Animals; Bone Resorption; Cattle; Cell Survival; Diphosphonates; Etidronic Acid; In Vitro Techniques; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Microscopy, Polarization; Osteoclasts; Pamidronate; Rats; Rats, Inbred Strains; Video Recording | 1990 |
Effects of a new bisphosphonate (AHBuBP) on osteolysis induced by human prostate cancer cells in nude mice.
Topics: Adenocarcinoma; Alendronate; Animals; Diphosphonates; Etidronic Acid; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Osteolysis; Pamidronate; Prostatic Neoplasms | 1990 |
Alendronate distributed on bone surfaces inhibits osteoclastic bone resorption in vitro and in experimental hypercalcemia models.
Topics: Alendronate; Animals; Autoradiography; Bone and Bones; Bone Resorption; Calcium; Carbon Radioisotopes; Diphosphonates; Disease Models, Animal; Dose-Response Relationship, Drug; Etidronic Acid; Hydroxycholecalciferols; Hypercalcemia; Male; Organ Culture Techniques; Osteoclasts; Pamidronate; Parathyroid Hormone; Phosphorus; Rats; Rats, Sprague-Dawley; Tibia; Tissue Distribution | 1995 |
Effects of treatment of malignancy-associated hypercalcemia on serum parathyroid hormone-related protein.
Topics: Alendronate; Calcitriol; Calcium; Creatinine; Diphosphonates; Female; Humans; Hypercalcemia; Male; Neoplasms; Pamidronate; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Phosphorus; Proteins | 1994 |
Bisphosphonates act on rat bone resorption through the mediation of osteoblasts.
Topics: Alendronate; Animals; Animals, Newborn; Bone Resorption; Cell Line; Cells, Cultured; Clodronic Acid; Culture Media, Conditioned; Diphosphonates; Dose-Response Relationship, Drug; Etidronic Acid; Ibandronic Acid; Kinetics; Osteoblasts; Pamidronate; Parathyroid Hormone; Rats; Rats, Wistar; Time Factors | 1993 |
Different effects of three bisphosphonates on nitric oxide production by RAW 264 macrophage-like cells in vitro.
Topics: Alendronate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Clodronic Acid; Diphosphonates; Female; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide; Pamidronate | 1996 |
Bisphosphonates induce apoptosis in mouse macrophage-like cells in vitro by a nitric oxide-independent mechanism.
Topics: Alendronate; Animals; Apoptosis; Bone Marrow; Bone Marrow Cells; Bone Resorption; Cell Division; Cell Nucleus; Cells, Cultured; Diphosphonates; DNA; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Ibandronic Acid; Macrophages; Mice; Necrosis; Nitric Oxide; Pamidronate; Protein Biosynthesis | 1996 |
Effects of bisphosphonates on alkaline phosphatase activity, mineralization, and prostaglandin E2 synthesis in the clonal osteoblast-like cell line MC3T3-E1.
Topics: Alendronate; Alkaline Phosphatase; Animals; Calcification, Physiologic; Calcium; Cell Line; Clodronic Acid; Culture Media; Dinoprostone; Diphosphonates; DNA; Glycerophosphates; Mice; Osteoblasts; Pamidronate | 1997 |
Nonclinical model for assessing gastric effects of bisphosphonates.
Topics: Alendronate; Animals; Chelating Agents; Diphosphonates; Edetic Acid; Egtazic Acid; Etidronic Acid; Indomethacin; Male; Pamidronate; Rats; Rats, Sprague-Dawley; Risedronic Acid; Stomach | 1997 |
Measurement of bone degradation products in serum using antibodies reactive with an isomerized form of an 8 amino acid sequence of the C-telopeptide of type I collagen.
Topics: Adult; Alendronate; Amino Acid Sequence; Antibodies; Biomarkers; Bone Resorption; Collagen; Collagen Type I; Cross Reactions; Diphosphonates; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hyperparathyroidism; Menopause; Menstruation; Middle Aged; Molecular Sequence Data; Osteitis Deformans; Osteoporosis; Pamidronate; Peptides; Sensitivity and Specificity | 1997 |
Rapid skeletal turnover and hypercalcemia associated with markedly elevated interleukin-6 levels in a young black man.
Topics: Adult; Alendronate; Alkaline Phosphatase; Black People; Bone and Bones; Bone Remodeling; Collagen; Collagen Type I; Diphosphonates; Humans; Hypercalcemia; Interleukin-6; Male; Osteoclasts; Osteolysis; Pamidronate; Peptides; Phosphates; Radionuclide Imaging | 1998 |
Bisphosphonates and tetracycline: experimental models for their evaluation in calcium-related disorders.
Topics: Alendronate; Animals; Anti-Inflammatory Agents; Betaine; Bone and Bones; Bone Resorption; Calcinosis; Chelating Agents; Diphosphonates; Edetic Acid; Hindlimb; Hydroxyapatites; Male; Pamidronate; Protein Synthesis Inhibitors; Rats; Structure-Activity Relationship; Tetracycline | 1998 |
Effects of continuous alendronate treatment on bone mass and mechanical properties in ovariectomized rats: comparison with pamidronate and etidronate in growing rats.
Topics: Alendronate; Animals; Biomechanical Phenomena; Body Weight; Bone and Bones; Bone Density; Diphosphonates; Etidronic Acid; Female; Ovariectomy; Pamidronate; Rats; Rats, Sprague-Dawley | 1998 |
The effect of alendronate on cytokine production, adhesion molecule expression, and transendothelial migration of human peripheral blood mononuclear cells.
Topics: Alendronate; Antigens, CD; Cell Adhesion Molecules; Cell Communication; Cell Movement; Cytokines; Diphosphonates; Endothelium; Flow Cytometry; Humans; Integrin alpha4; Integrin alpha4beta1; Integrin beta1; Integrins; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-1; Leukocytes, Mononuclear; Pamidronate; Phenotype; Receptors, Lymphocyte Homing; Tumor Necrosis Factor-alpha | 1998 |
Skin reactions associated with bisphosphonates: a report of 3 cases and an approach to management.
Topics: Adult; Alendronate; Antineoplastic Agents; Breast Neoplasms; Clodronic Acid; Diphosphonates; Drug Hypersensitivity; Etidronic Acid; Female; Humans; Middle Aged; Pamidronate; Skin Tests; Urticaria | 1998 |
The effects of nitrogen-containing bisphosphonates on human epithelial (Caco-2) cells, an in vitro model for intestinal epithelium.
Topics: Alendronate; Apoptosis; Caco-2 Cells; Calcium; Cell Survival; Diphosphonates; Epithelial Cells; Humans; Intestinal Mucosa; Models, Biological; Nitrogen; Pamidronate; Solubility; Structure-Activity Relationship | 1999 |
MMP inhibition and downregulation by bisphosphonates.
Topics: Alendronate; Antineoplastic Agents; Body Fluids; Collagenases; Diphosphonates; Gene Expression Regulation, Enzymologic; Humans; Metalloendopeptidases; Neoplasm Invasiveness; Pamidronate; Protease Inhibitors; Tumor Cells, Cultured | 1999 |
Synthesis and preclinical pharmacology of 2-(2-aminopyrimidinio) ethylidene-1,1-bisphosphonic acid betaine (ISA-13-1)-a novel bisphosphonate.
Topics: Administration, Oral; Alendronate; Animals; Antineoplastic Agents; Betaine; Bone Diseases; Bone Neoplasms; Calcium; Capsules; Carcinoma 256, Walker; Cell Line; Diphosphonates; Diuretics, Osmotic; Durapatite; Injections, Intravenous; Intestinal Absorption; Macrophages; Male; Mannitol; Osteogenesis; Pamidronate; Rats; Rats, Inbred Strains; Tight Junctions; Tissue Distribution | 1999 |
Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin.
Topics: Alendronate; Animals; Apoptosis; Calcitonin; Cell Line; Cells, Cultured; Dexamethasone; Diphosphonates; Etidronic Acid; Etoposide; In Situ Nick-End Labeling; Mice; Osteoblasts; Osteocytes; Pamidronate; Prednisolone; Skull; Tumor Necrosis Factor-alpha | 1999 |
N-bisphosphonates cause gastric epithelial injury independent of effects on the microcirculation.
Topics: Administration, Topical; Alendronate; Animals; Dinoprostone; Diphosphonates; Drug Interactions; Epithelium; Male; Microcirculation; Neutrophil Infiltration; Nitric Oxide; Nitric Oxide Donors; Pamidronate; Rats; Rats, Wistar; Stomach; Time Factors | 1999 |
Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase.
Topics: Alendronate; Alkyl and Aryl Transferases; Animals; Carbon-Carbon Double Bond Isomerases; Diphosphonates; Enzyme Inhibitors; Farnesyltranstransferase; Geranyltranstransferase; Hemiterpenes; Humans; In Vitro Techniques; Kinetics; Lipids; Liver; Male; Mevalonic Acid; Osteoclasts; Pamidronate; Protein Prenylation; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 2000 |
A 73-year-old woman with osteoporosis, 1 year later.
Topics: Aged; Alendronate; Diphosphonates; Female; Humans; Osteoporosis; Pamidronate | 2000 |
Stimulation of gammadelta T cells by aminobisphosphonates and induction of antiplasma cell activity in multiple myeloma.
Topics: Alendronate; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Bone Marrow Cells; Cell Division; Cell Survival; Cytotoxicity, Immunologic; Diphosphonates; Humans; Ibandronic Acid; Interferon-gamma; Interleukin-2; Kinetics; Lectins, C-Type; Lymphocyte Activation; Multiple Myeloma; Pamidronate; Plasma Cells; Receptors, Interleukin-2; T-Lymphocytes; Tumor Cells, Cultured | 2000 |
Gastric damage in the rat with nitrogen-containing bisphosphonates depends on pH.
Topics: Administration, Oral; Alendronate; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Diphosphonates; Etidronic Acid; Hydrogen-Ion Concentration; Indomethacin; Male; Pamidronate; Rats; Rats, Sprague-Dawley; Risedronic Acid; Stomach; Structure-Activity Relationship | 2000 |
Case of an ivory vertebra.
Topics: Alendronate; Alkaline Phosphatase; Biopsy; Bone Marrow; Carcinoid Tumor; Diagnosis, Differential; Diphosphonates; Humans; Liver Neoplasms; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Metastasis; Osteitis Deformans; Osteoblasts; Pamidronate; Spinal Neoplasms; Technetium; Tomography, X-Ray Computed | 2000 |
Effect of bisphosphonates on surface hydrophobicity and phosphatidylcholine concentration of rodent gastric mucosa.
Topics: Alendronate; Animals; Anti-Inflammatory Agents; Diphosphonates; Etidronic Acid; Gastric Mucosa; Indomethacin; Male; Pamidronate; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Risedronic Acid; Surface Properties | 2000 |
Bisphosphonate therapy in fibrous dysplasia.
Topics: Administration, Oral; Adult; Aged; Alendronate; Biomarkers; Bone and Bones; Collagen; Collagen Type I; Diphosphonates; Female; Fibrous Dysplasia of Bone; Follow-Up Studies; Fractures, Spontaneous; Humans; Injections, Intravenous; Male; Middle Aged; Osteogenesis; Osteolysis; Pain Measurement; Pamidronate; Peptides; Radiography; Statistics, Nonparametric | 2001 |
Vgamma2Vdelta2 T-cell receptor-mediated recognition of aminobisphosphonates.
Topics: Alendronate; Antigens; Cell Line, Transformed; Cytotoxicity, Immunologic; Diphosphonates; Etidronic Acid; Gene Rearrangement, delta-Chain T-Cell Antigen Receptor; Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor; Humans; Interferon-gamma; Interleukin-2; Jurkat Cells; Lymphocyte Activation; Monocytes; Multiple Myeloma; Neoplasms; Neoplastic Stem Cells; Osteoclasts; Osteoporosis; Pamidronate; Receptors, Antigen, T-Cell, gamma-delta; Recombinant Fusion Proteins; Risedronic Acid; Structure-Activity Relationship; T-Lymphocyte Subsets; Transfection | 2001 |
Bisphosphonate therapy for Paget's disease in a patient with hypoparathyroidism: profound hypocalcemia, rapid response, and prolonged remission.
Topics: Alendronate; Calcitriol; Calcium; Cervical Vertebrae; Diphosphonates; Female; Humans; Hypocalcemia; Hypoparathyroidism; Middle Aged; Osteitis Deformans; Pamidronate; Pelvis; Scapula; Tibia; Time Factors; Treatment Outcome | 2001 |
Do different aminobisphosphonates have similar preventive effect on experimental thyroid hormone-induced osteopenia in rats?
Topics: Alendronate; Animals; Body Weight; Bone Diseases, Metabolic; Diphosphonates; Female; Pamidronate; Rats; Rats, Sprague-Dawley; Thyroxine | 2001 |
Synthesis, characterization and biodistribution of bisphosphonates Sm-153 complexes: correlation with molecular modeling interaction studies.
Topics: Alendronate; Animals; Bone and Bones; Diphosphonates; Durapatite; Energy Transfer; Female; Mice; Models, Molecular; Molecular Conformation; Pamidronate; Radiochemistry; Radioisotopes; Radiopharmaceuticals; Samarium; Tissue Distribution | 2002 |
Inhibitory action of bisphosphonates on bone resorption does not involve the regulation of RANKL and OPG expression.
Topics: Alendronate; Animals; Bone Resorption; Carrier Proteins; Cells, Cultured; Diphosphonates; Gene Expression Regulation; Glycoproteins; Membrane Glycoproteins; Mice; Mice, Inbred ICR; Osteoblasts; Osteoclasts; Osteoprotegerin; Pamidronate; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction | 2002 |
Intravenous pamidronate compared with oral alendronate for the treatment of postmenopausal osteoporosis.
Topics: Administration, Oral; Aged; Alendronate; Bone Density; Diphosphonates; Female; Fractures, Spontaneous; Humans; Injections, Intravenous; Lumbar Vertebrae; Middle Aged; Osteoporosis, Postmenopausal; Pamidronate; Radiography; Retrospective Studies; Spinal Fractures; Time Factors | 2002 |
A quantitative structure-activity relationship and pharmacophore modeling investigation of aryl-X and heterocyclic bisphosphonates as bone resorption agents.
Topics: Alendronate; Bone Resorption; Diphosphonates; Heterocyclic Compounds; Models, Molecular; Pamidronate; Quantitative Structure-Activity Relationship | 2003 |
Bisphosphonates induce apoptosis of stromal tumor cells in giant cell tumor of bone.
Topics: Alendronate; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Diphosphonates; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Flow Cytometry; Giant Cell Tumor of Bone; Humans; Imidazoles; In Situ Nick-End Labeling; Osteoclasts; Pamidronate; Stromal Cells; Tumor Cells, Cultured; Zoledronic Acid | 2004 |
By the way, doctor. My wife is 80. In order to increase her bone calcium, she takes calcium citrate tablets. Her doctor now wants to put her on Aredia by IV injection every three months. Since this is not FDA approved, is it a good idea?
Topics: Aged; Aged, 80 and over; Alendronate; Antineoplastic Agents; Calcium Citrate; Diphosphonates; Female; Humans; Osteoporosis; Pamidronate | 2004 |
In vitro toxicity of bisphosphonates on human neuroblastoma cell lines.
Topics: Alendronate; Apoptosis; Cell Line, Tumor; Cell Proliferation; Clodronic Acid; Diphosphonates; Drug Screening Assays, Antitumor; Germany; Humans; Ibandronic Acid; Imidazoles; Neuroblastoma; Pamidronate; Time Factors; Zoledronic Acid | 2004 |
Bisphosphonates and avascular necrosis of the jaw: a possible association.
Topics: Aged; Aged, 80 and over; Alendronate; Anti-Inflammatory Agents; Diphosphonates; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Long-Term Care; Male; Mandibular Diseases; Maxillary Diseases; Middle Aged; Multiple Myeloma; Osteitis Deformans; Osteonecrosis; Pamidronate; Risk Factors; Tomography, X-Ray Computed | 2005 |
The effect of intravenous pamidronate versus oral alendronate on bone mineral density in patients with osteoporosis.
Topics: Absorptiometry, Photon; Administration, Oral; Aged; Aged, 80 and over; Alendronate; Anti-Inflammatory Agents; Bone Density; Bone Density Conservation Agents; Diphosphonates; Female; Hip; Humans; Injections, Intravenous; Male; Middle Aged; Osteoporosis; Pamidronate; Prospective Studies; Spine | 2005 |
Bone-specific alkaline phosphatase activity is inhibited by bisphosphonates: role of divalent cations.
Topics: Alendronate; Alkaline Phosphatase; Animals; Bone and Bones; Bone Resorption; Cations, Divalent; Diphosphonates; Imidazoles; Isoenzymes; Magnesium; Osteoblasts; Osteosarcoma; Pamidronate; Rats; Tumor Cells, Cultured; Zinc; Zoledronic Acid | 2005 |
Bisphosphonates decrease telomerase activity and hTERT expression in MCF-7 breast cancer cells.
Topics: Alendronate; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Clodronic Acid; Diphosphonates; DNA-Binding Proteins; Female; Gene Expression; Humans; Pamidronate; Telomerase; Tumor Cells, Cultured | 2005 |
Osteonecrosis of the jaw and bisphosphonates.
Topics: Alendronate; Animals; Diphosphonates; Humans; Imidazoles; Jaw Diseases; Osteonecrosis; Osteoporosis; Pamidronate; Zoledronic Acid | 2005 |
High-performance liquid chromatography method for determining alendronate sodium in human plasma by detecting fluorescence: application to a pharmacokinetic study in humans.
Topics: Alendronate; Bone Density Conservation Agents; Calibration; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citrates; Diphosphonates; Fluorenes; Humans; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Pamidronate; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Time Factors; Trichloroacetic Acid | 2006 |
Bisphosphonate-associated osteonecrosis of the jaws and endodontic treatment: two case reports.
Topics: Aged; Alendronate; Bone Density Conservation Agents; Diphosphonates; Humans; Imidazoles; Jaw Diseases; Male; Osteonecrosis; Pamidronate; Zoledronic Acid | 2005 |
Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment.
Topics: Abscess; Alendronate; Antineoplastic Agents; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Dental Caries; Dexamethasone; Diphosphonates; Drug Interactions; Female; Humans; Hyperostosis; Imidazoles; Jaw Diseases; Male; Multiple Myeloma; Osteonecrosis; Osteopetrosis; Osteoporosis; Pamidronate; Periodontitis; Prostatic Neoplasms; Risk Factors; Tooth Extraction; Zoledronic Acid | 2005 |
[Osteonecrosis of the jaws as a possible adverse effect of the use of bisphosphonates].
Topics: Aged; Alendronate; Diphosphonates; Female; Follow-Up Studies; Humans; Imidazoles; Male; Mandibular Diseases; Maxillary Diseases; Middle Aged; Mouth Diseases; Osteonecrosis; Osteoporosis, Postmenopausal; Pamidronate; Plasmacytoma; Radiography, Panoramic; Risk Factors; Zoledronic Acid | 2005 |
By the way, doctor. I've heard that taking Fosamax for a long time causes the jawbone to deteriorate. Do you know anything about this?
Topics: Alendronate; Bone Density Conservation Agents; Diphosphonates; Female; Humans; Imidazoles; Osteoclasts; Osteonecrosis; Pamidronate; Zoledronic Acid | 2005 |
Relationship between periodontal disease and systemic diseases.
Topics: Alendronate; Bone Density Conservation Agents; Contraindications; Dental Implantation, Endosseous; Diphosphonates; Humans; Imidazoles; Infusions, Intravenous; Jaw Diseases; Osteonecrosis; Pamidronate; Zoledronic Acid | 2006 |
Differential effects of bisphosphonates on breast cancer cell lines.
Topics: Alendronate; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Clodronic Acid; Cyclin D1; Diphosphonates; DNA Fragmentation; Etidronic Acid; Female; Flow Cytometry; Humans; Ibandronic Acid; Imidazoles; Pamidronate; Risedronic Acid; RNA, Messenger; Zoledronic Acid | 2007 |
Evaluation of multidimensional capillary electrophoretic methodologies for determination of amino bisphosphonate pharmaceuticals.
Topics: Alendronate; Diphosphonates; Electrophoresis, Capillary; Humans; Pamidronate; Reproducibility of Results | 2006 |
Bisphosphonate-associated osteonecrosis of the jaw in patients with multiple myeloma and breast cancer.
Topics: Alendronate; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Diphosphonates; Female; Humans; Imidazoles; Jaw Diseases; Male; Mandible; Maxilla; Middle Aged; Multiple Myeloma; Necrosis; Osteonecrosis; Pamidronate; Tomography, X-Ray Computed; Zoledronic Acid | 2007 |
Bone necrosis of the jaws associated with bisphosphonate treatment: a report of twenty-nine cases.
Topics: Aged; Aged, 80 and over; Alendronate; Anti-Bacterial Agents; Antifungal Agents; Bone Density Conservation Agents; Bone Neoplasms; Chlorhexidine; Curettage; Diphosphonates; Female; Humans; Hydrogen Peroxide; Imidazoles; Jaw Diseases; Male; Mandibular Diseases; Maxillary Diseases; Middle Aged; Mouthwashes; Multiple Myeloma; Osteonecrosis; Osteoporosis; Pamidronate; Radiography; Time Factors; Zoledronic Acid | 2006 |
Amino-bisphosphonates decrease hTERT gene expression in breast cancer in vitro.
Topics: Alendronate; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Clodronic Acid; Diphosphonates; Female; Gene Expression Regulation, Neoplastic; Humans; Pamidronate; Telomerase | 2007 |
[Advances in the research of bisphosphonate-associated osteonecrosis of the jaws].
Topics: Alendronate; Biomedical Research; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Diphosphonates; Humans; Osteonecrosis; Pamidronate | 2006 |
Development and application of a high-performance liquid chromatography-mass spectrometry method to determine alendronate in human urine.
Topics: Alendronate; Biological Availability; Chromatography, High Pressure Liquid; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Mass Spectrometry; Pamidronate; Reference Standards | 2007 |
NMR investigations of the static and dynamic structures of bisphosphonates on human bone: a molecular model.
Topics: Alendronate; Biochemistry; Bone and Bones; Bone Density Conservation Agents; Crystallography, X-Ray; Diphosphonates; Etidronic Acid; Humans; Hydrogen; Imidazoles; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Pamidronate; Protein Structure, Tertiary; Risedronic Acid; Zoledronic Acid | 2008 |
Metaphyseal sclerosis associated with bisphosphonate therapy.
Topics: Alendronate; Bone and Bones; Bone Density Conservation Agents; Dermatomyositis; Diphosphonates; Humans; Osteogenesis Imperfecta; Pamidronate; Radiography; Sclerosis | 2007 |
Comment on: Bisphosphonates and osteonecrosis of the jaw.
Topics: Administration, Oral; Adolescent; Adult; Alendronate; Child; Child, Preschool; Diphosphonates; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Jaw Diseases; Male; Osteonecrosis; Pamidronate; Prospective Studies; Risk Assessment | 2008 |
Aminobisphosphonates cause osteoblast apoptosis and inhibit bone nodule formation in vitro.
Topics: Alendronate; Animals; Animals, Newborn; Apoptosis; Bone Density Conservation Agents; Calcification, Physiologic; Cell Survival; Cells, Cultured; Collagen; Diphosphonates; Dose-Response Relationship, Drug; Mice; Osteoblasts; Osteocalcin; Osteoclasts; Osteogenesis; Pamidronate; Protein Prenylation; Rabbits; Skull | 2008 |
Effects of alendronate and pamidronate on cultured rat metatarsal bones: failure to prevent dexamethasone-induced growth retardation.
Topics: Alendronate; Animals; Bone Density; Cell Differentiation; Cell Line; Cell Proliferation; Chondrocytes; Cytoprotection; Dexamethasone; Diphosphonates; Foot Bones; Humans; Pamidronate; Rats; Rats, Sprague-Dawley; Tissue Culture Techniques | 2008 |
Postmarketing surveillance rates of uveitis and scleritis with bisphosphonates among a national veteran cohort.
Topics: Administration, Oral; Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Databases, Factual; Diphosphonates; Drug Prescriptions; Female; Humans; Infusions, Parenteral; Male; Middle Aged; Pamidronate; Pharmacy Service, Hospital; Product Surveillance, Postmarketing; Scleritis; United States; United States Department of Veterans Affairs; Uveitis; Veterans | 2008 |
Enhanced bone morphogenetic protein-2 performance on hydroxyapatite ceramic surfaces.
Topics: Alendronate; Animals; Bone Morphogenetic Protein 2; Cell Differentiation; Cell Line; Ceramics; Coated Materials, Biocompatible; Diphosphonates; Durapatite; Immobilized Proteins; Mice; Muramidase; Osteoblasts; Pamidronate | 2009 |
Opposing effects of bisphosphonates and advanced glycation end-products on osteoblastic cells.
Topics: 3T3 Cells; Alendronate; Animals; Bone Density Conservation Agents; Calcium; Calcium Channels, L-Type; Cattle; Cell Line; Diabetes Complications; Diphosphonates; Dose-Response Relationship, Drug; Glycation End Products, Advanced; Imidazoles; Mice; Osteoblasts; Osteoporosis; Pamidronate; Rats; Reactive Oxygen Species; Serum Albumin, Bovine; Time Factors; Zoledronic Acid | 2008 |
Alendronate and Pamidronate calcium phosphate bone cements: setting properties and in vitro response of osteoblast and osteoclast cells.
Topics: Alendronate; Bone Cements; Bone Density Conservation Agents; Calcium Phosphates; Cell Differentiation; Cell Line; Cell Proliferation; Diphosphonates; Humans; Microscopy, Electron, Scanning; Osteoblasts; Osteoclasts; Pamidronate | 2009 |
Postmarketing surveillance rates of uveitis and scleritis with bisphosphonates among a national veteran cohort.
Topics: Administration, Oral; Alendronate; Bone Density Conservation Agents; Databases, Factual; Diphosphonates; Drug Prescriptions; Humans; Infusions, Parenteral; Pamidronate; Pharmacy Service, Hospital; Product Surveillance, Postmarketing; Scleritis; United States; United States Department of Veterans Affairs; Uveitis; Veterans | 2009 |
Bisphosphonate-related osteonecrosis of the jaws: a single-center study of 101 patients.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Alendronate; Angiogenesis Inhibitors; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bone Density Conservation Agents; Diabetes Mellitus, Type 2; Diphosphonates; Female; Follow-Up Studies; Glucocorticoids; Humans; Imidazoles; Injections, Intravenous; Jaw Diseases; Male; Middle Aged; Minimally Invasive Surgical Procedures; Oral Surgical Procedures; Osteonecrosis; Pamidronate; Risk Factors; Smoking; Time Factors; Treatment Outcome; Wound Healing; Zoledronic Acid | 2009 |
Outcome of surgical management of bisphosphonate-related osteonecrosis of the jaws: review of 33 surgical cases.
Topics: Adult; Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Diphosphonates; Female; Humans; Imidazoles; Jaw Diseases; Male; Middle Aged; Osteonecrosis; Pamidronate; Treatment Outcome; Zoledronic Acid | 2009 |
Intravenous bisphosphonate-related osteonecrosis of the jaw: bone scintigraphy as an early indicator.
Topics: Administration, Oral; Alendronate; Bone Density Conservation Agents; Diphosphonates; Early Diagnosis; Female; Humans; Imidazoles; Injections, Intravenous; Jaw Diseases; Male; Middle Aged; Neoplasms; Osteonecrosis; Pamidronate; Radionuclide Imaging; Radiopharmaceuticals; Retrospective Studies; Technetium Compounds; Zoledronic Acid | 2009 |
Importance of microcracks in etiology of bisphosphonate-related osteonecrosis of the jaw: a possible pathogenetic model of symptomatic and non-symptomatic osteonecrosis of the jaw based on scanning electron microscopy findings.
Topics: Adult; Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Connective Tissue; Diphosphonates; Female; Humans; Imidazoles; Inflammation; Jaw; Jaw Diseases; Male; Mandibular Diseases; Maxillary Diseases; Microscopy, Electron, Scanning; Middle Aged; Osteomyelitis; Osteonecrosis; Osteoporosis; Osteoradionecrosis; Pamidronate; Time Factors; Zoledronic Acid | 2010 |
In vitro determination of the release of alendronic acid from alendronate tablets of different brands during deglutition.
Topics: Alendronate; Algorithms; Bone Density Conservation Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Deglutition; Diphosphonates; Drugs, Generic; Indicators and Reagents; Kinetics; Pamidronate; Solubility; Solvents; Tablets; Therapeutic Equivalency | 2009 |
Inhibition of necrotic actions of nitrogen-containing bisphosphonates (NBPs) and their elimination from bone by etidronate (a non-NBP): a proposal for possible utilization of etidronate as a substitution drug for NBPs.
Topics: Alendronate; Animals; Bone Density Conservation Agents; Bone Resorption; Diphosphonates; Ear, External; Etidronic Acid; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Inflammation Mediators; Injections, Intraperitoneal; Injections, Subcutaneous; Interleukin-1; Male; Mice; Mice, Inbred BALB C; Necrosis; Osteonecrosis; Osteosclerosis; Pamidronate; Pravastatin; Radionuclide Imaging; Radiopharmaceuticals; Risedronic Acid; Technetium; Tibia; Time Factors; Zoledronic Acid | 2010 |
An in vitro assay to measure targeted drug delivery to bone mineral.
Topics: Alendronate; Anabolic Agents; Bone and Bones; Bone Density Conservation Agents; Diphosphonates; Drug Delivery Systems; Durapatite; Etidronic Acid; Humans; Ibandronic Acid; Imidazoles; Nuclear Magnetic Resonance, Biomolecular; Pamidronate; Risedronic Acid; Zoledronic Acid | 2010 |
Use of cone-beam computerized tomography for evaluation of bisphosphonate-associated osteonecrosis of the jaws.
Topics: Adult; Aged; Alendronate; Bone Density Conservation Agents; Cone-Beam Computed Tomography; Diphosphonates; Dry Socket; Female; Humans; Imaging, Three-Dimensional; Imidazoles; Male; Mandibular Diseases; Maxillary Diseases; Middle Aged; Oroantral Fistula; Osteonecrosis; Osteosclerosis; Pamidronate; Radiography, Dental, Digital; Radiography, Panoramic; Tooth Socket; Zoledronic Acid | 2010 |
Possible beneficial effect of bisphosphonates in osteonecrosis of the knee.
Topics: Alendronate; Alkaline Phosphatase; Amino Acids; Bone Density Conservation Agents; Bone Marrow Diseases; Collagen Type I; Diphosphonates; Edema; Humans; Knee; Leg Bones; Magnetic Resonance Imaging; Middle Aged; Osteocalcin; Osteonecrosis; Pain Measurement; Pamidronate; Peptide Fragments; Peptides; Procollagen; Prospective Studies | 2010 |
Treatment outcomes in patients with bisphosphonate-related osteonecrosis of the jaws: a prospective study.
Topics: Aged; Alcohol Drinking; Alendronate; Anti-Bacterial Agents; Bone Density Conservation Agents; Chronic Disease; Clindamycin; Cohort Studies; Combined Modality Therapy; Debridement; Diphosphonates; Female; Follow-Up Studies; Fractures, Spontaneous; Humans; Imidazoles; Jaw Diseases; Male; Oral Fistula; Osteonecrosis; Pamidronate; Penicillins; Prospective Studies; Remission Induction; Risk Factors; Smoking; Tooth Extraction; Treatment Outcome; Wound Healing; Zoledronic Acid | 2010 |
Bisphosphonate protonation states, conformations, and dynamics on bone mineral probed by solid-state NMR without isotope enrichment.
Topics: Alendronate; Animals; Bone Density; Bone Density Conservation Agents; Crystallization; Diphosphonates; Horses; Imidazoles; Magnetic Resonance Spectroscopy; Molecular Structure; Pamidronate; Structure-Activity Relationship; Technology, Pharmaceutical; Zoledronic Acid | 2010 |
Effect of bisphosphonates on human gingival fibroblast production of mediators of osteoclastogenesis: RANKL, osteoprotegerin and interleukin-6.
Topics: Alendronate; Analysis of Variance; Bone Density Conservation Agents; Bone Remodeling; Cells, Cultured; Diphosphonates; Fibroblasts; Gingiva; Humans; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Necrosis; Osteoclasts; Osteoprotegerin; Pamidronate; RANK Ligand; Statistics, Nonparametric | 2011 |
Acute effects of intravenous administration of pamidronate in patients with osteoporosis.
Topics: Acute-Phase Proteins; Adult; Aged; Aged, 80 and over; Alendronate; Biomarkers; Blood Cells; Bone Density Conservation Agents; C-Reactive Protein; Calcium; Collagen Type I; Diphosphonates; Female; Humans; Injections, Intravenous; Interferon-gamma; Interleukin-6; Male; Middle Aged; Osteoporosis; Pamidronate; Peptides; RNA, Messenger; Tumor Necrosis Factor-alpha | 2010 |
Breast cancer cells inhibit spontaneous and bisphosphonate-induced osteoclast apoptosis.
Topics: Alendronate; Animals; Apoptosis; Bone Density Conservation Agents; Bone Resorption; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cells, Cultured; Diphosphonates; Female; Humans; Immunoblotting; Mice; Microspectrophotometry; Osteoclasts; Pamidronate; Polymerase Chain Reaction | 2011 |
Use of bisphosphonates to treat severe idiopathic hypercalcaemia in a young Ragdoll cat.
Topics: Alendronate; Animals; Bone Density Conservation Agents; Cat Diseases; Cats; Diphosphonates; Female; Follow-Up Studies; Hypercalcemia; Pamidronate; Severity of Illness Index; Treatment Outcome | 2011 |
99mTc(CO)3-labeled pamidronate and alendronate for bone imaging.
Topics: Alendronate; Animals; Bone and Bones; Crystallography, X-Ray; Diphosphonates; Female; Mice; Molecular Conformation; Pamidronate; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Technetium; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2011 |
[Prosthetic rehabilitation after osteonecrosis of the jaws due to histiocytosis X and treatment with bisphosphonates apropos of a case].
Topics: Adult; Alendronate; Bone Density Conservation Agents; Denture Design; Denture, Partial, Fixed; Denture, Partial, Temporary; Diphosphonates; Female; Histiocytosis, Langerhans-Cell; Humans; Imidazoles; Jaw, Edentulous, Partially; Mandibular Diseases; Osteonecrosis; Pamidronate; Risk Factors; Tooth Extraction; Zoledronic Acid | 2010 |
N⁴-[Alkyl-(hydroxyphosphono)phosphonate]-cytidine-new drugs covalently linking antimetabolites (5-FdU, araU or AZT) with bone-targeting bisphosphonates (alendronate or pamidronate).
Topics: Alendronate; Animals; Antimetabolites, Antineoplastic; Arabinofuranosyluracil; Bone and Bones; Bone Density Conservation Agents; Cell Line, Tumor; Cytidine; Diphosphonates; Drug Screening Assays, Antitumor; Durapatite; Fluorouracil; Humans; Macrophages; Mice; Pamidronate; Uridine; Zidovudine | 2011 |
Bisphosphonates modulate the expression of OPG and M-CSF in hMSC-derived osteoblasts.
Topics: Alendronate; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Cell Culture Techniques; Cell Differentiation; Culture Media; Diphosphonates; Enzyme-Linked Immunosorbent Assay; Glyceraldehyde 3-Phosphate Dehydrogenase (NADP+); Humans; Macrophage Colony-Stimulating Factor; Male; Mesenchymal Stem Cells; Osteoblasts; Osteoclasts; Osteogenesis; Osteoprotegerin; Pamidronate; Real-Time Polymerase Chain Reaction; Time Factors; Young Adult | 2012 |
[Inflammation of the jaws during treatment with bisphosphonates].
Topics: Administration, Oral; Aged; Alendronate; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Diphosphonates; Drug Approval; Female; Humans; Imidazoles; Infusions, Intravenous; Jaw Diseases; Opportunistic Infections; Osteomyelitis; Osteonecrosis; Osteoporosis; Pamidronate; Practice Guidelines as Topic; Risk Factors; Zoledronic Acid | 2011 |
The cytotoxic effects of three different bisphosphonates in-vitro on human gingival fibroblasts, osteoblasts and osteogenic sarcoma cells.
Topics: Alendronate; Alkaline Phosphatase; Bone Density Conservation Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Collagen Type I; Coloring Agents; Diphosphates; Diphosphonates; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Follow-Up Studies; Gingiva; Humans; Imidazoles; Osteoblasts; Osteocalcin; Osteosarcoma; Pamidronate; Tetrazolium Salts; Thiazoles; Zoledronic Acid | 2012 |
Uncommon transient osteoporosis of pregnancy at multiple sites associated with cytomegalovirus infection: is there a link?
Topics: Absorptiometry, Photon; Adult; Alendronate; Ankle Joint; Bone Density Conservation Agents; Cytomegalovirus Infections; Diphosphonates; Female; Hip Joint; Humans; Knee Joint; Magnetic Resonance Imaging; Osteoporosis; Pamidronate; Pregnancy; Pregnancy Complications; Radionuclide Imaging | 2011 |
Cutting edge: nitrogen bisphosphonate-induced inflammation is dependent upon mast cells and IL-1.
Topics: Alendronate; Animals; Chemotaxis; Clodronic Acid; Diphosphonates; Imidazoles; Interleukin-1alpha; Interleukin-1beta; Leukocytes; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Myeloid Differentiation Factor 88; Neutrophils; Pamidronate; Peritonitis; Receptors, Interleukin-1; Zoledronic Acid | 2012 |
Osteopathology induced by bisphosphonates and dental implants: clinical observations.
Topics: Actinomycosis; Administration, Intravenous; Administration, Oral; Alendronate; Anti-Bacterial Agents; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Cone-Beam Computed Tomography; Debridement; Dental Implants; Diphosphonates; Female; Follow-Up Studies; Humans; Ibandronic Acid; Imidazoles; Male; Mandible; Mandibular Neoplasms; Maxilla; Neoplasms; Osteomyelitis; Osteoporosis; Pamidronate; Risk Factors; Time Factors; Zoledronic Acid | 2013 |
[Simultaneous determination of alendronate, pamidronate, ibandronate and risedronate using ion chromatography with integrated pulsed amperometric detection].
Topics: Alendronate; Chromatography, Ion Exchange; Diphosphonates; Electrochemical Techniques; Etidronic Acid; Humans; Ibandronic Acid; Pamidronate; Risedronic Acid | 2012 |
Healing of extraction sockets and augmented alveolar defects following 1-year treatment with bisphosphonate.
Topics: Alendronate; Alveolar Ridge Augmentation; Animals; Bone Transplantation; Collagen Type I; Cone-Beam Computed Tomography; Diphosphonates; Dogs; Female; Humans; Mandible; Pamidronate; Peptides; Random Allocation; Surgical Flaps; Tooth Extraction; Transplantation, Homologous; Wound Healing | 2013 |
Effect of bisphosphonates on the rapidly growing male murine skeleton.
Topics: Alendronate; Animals; Apoptosis; Biomechanical Phenomena; Bone and Bones; Bone Development; Bone Resorption; Chondrocytes; Clodronic Acid; Diphosphonates; Hypertrophy; Imidazoles; Male; Mice; Mice, Inbred C57BL; Pamidronate; Phenotype; X-Ray Microtomography; Zoledronic Acid | 2014 |
A simple evaluation method for early detection of bisphosphonate-related osteonecrosis of the mandible using computed tomography.
Topics: Administration, Intravenous; Administration, Oral; Alendronate; Alveolar Process; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density; Bone Density Conservation Agents; Case-Control Studies; Diphosphonates; Early Diagnosis; Etidronic Acid; Female; Humans; Image Processing, Computer-Assisted; Imidazoles; Male; Mandible; Mandibular Diseases; Middle Aged; Osteolysis; Osteosclerosis; Pamidronate; Risedronic Acid; Risk Factors; Time Factors; Tomography, X-Ray Computed; Zoledronic Acid | 2014 |
[Effects of four bisphosphonates on macrophage phagocytosis: quantitative measurement by flow cytometry using high-fluorescence particles and human monocytic cell line THP-1].
Topics: Alendronate; Apoptosis; Bone Density Conservation Agents; Cell Line; Diphosphonates; Flow Cytometry; Fluorescent Dyes; Humans; Imidazoles; Macrophages; Pamidronate; Phagocytosis; Zoledronic Acid | 2014 |
High doses of bisphosphonates reduce osteoblast-like cell proliferation by arresting the cell cycle and inducing apoptosis.
Topics: Alendronate; Apoptosis; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Clodronic Acid; Coloring Agents; Diphosphonates; Dose-Response Relationship, Drug; Flow Cytometry; G1 Phase; Humans; Ibandronic Acid; Necrosis; Osteoblasts; Pamidronate; Resting Phase, Cell Cycle; Spectrophotometry; Tetrazolium Salts; Thiazoles; Time Factors | 2015 |
Effects of alendronate and pamidronate on apoptosis and cell proliferation in cultured primary human gingival fibroblasts.
Topics: Adolescent; Adult; Alendronate; Apoptosis; Bone Density Conservation Agents; Cell Proliferation; Cells, Cultured; Diphosphonates; Female; Fibroblasts; Gingiva; Humans; Male; Pamidronate; Young Adult | 2015 |
Concentration-dependent effects of alendronate and pamidronate functionalized gold nanoparticles on osteoclast and osteoblast viability.
Topics: Alendronate; Animals; Cell Survival; Diphosphonates; Dose-Response Relationship, Drug; Gold; Metal Nanoparticles; Mice; Osteoblasts; Osteoclasts; Pamidronate; RAW 264.7 Cells | 2017 |
[Bisphosphonate use and related pharmaceutical issues II].
Topics: Administration, Oral; Alendronate; Bone Density Conservation Agents; Bone Neoplasms; Clodronic Acid; Confounding Factors, Epidemiologic; Diphosphonates; Drug Costs; Drug Prescriptions; Drugs, Generic; Humans; Hungary; Ibandronic Acid; Imidazoles; National Health Programs; Osteoporosis; Pamidronate; Retrospective Studies; Risedronic Acid; Zoledronic Acid | 2016 |
The Bisphosphonate Pamidronate is an Intestinal Antiinflammatory Agent in Rat and Mouse Experimental Colitis.
Topics: Alendronate; Animals; Anti-Inflammatory Agents; Colitis; Dextran Sulfate; Diphosphonates; Ibandronic Acid; Immunologic Factors; Intestinal Mucosa; Mice; Pamidronate; Rats; T-Lymphocytes; Trinitrobenzenesulfonic Acid | 2016 |
New insights into human farnesyl pyrophosphate synthase inhibition by second-generation bisphosphonate drugs.
Topics: Alendronate; Binding Sites; Bone Density Conservation Agents; Diphosphonates; Drug Discovery; Geranyltranstransferase; Hemiterpenes; Humans; Molecular Dynamics Simulation; Organophosphorus Compounds; Pamidronate; Protein Binding; Structure-Activity Relationship; Thermodynamics | 2017 |
Clinical significance of increased serum levels of FGF-23 in fibrous dysplasia.
Topics: Adult; Aged; Alendronate; Biomarkers; Bone Density Conservation Agents; Female; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibrous Dysplasia of Bone; Humans; Male; Middle Aged; Osteomalacia; Pamidronate; Phosphorus; Reference Values; Young Adult; Zoledronic Acid | 2018 |
Immediate implant placement following 1-year treatment with oral versus intravenous bisphosphonates: a histomorphometric canine study on peri-implant bone.
Topics: Alendronate; Animals; Bone Density Conservation Agents; Dental Implantation, Endosseous; Dental Implants; Dogs; Female; Osseointegration; Pamidronate | 2019 |
Tissue-Nonspecific Alkaline Phosphatase (TNAP) as the Enzyme Involved in the Degradation of Nucleotide Analogues in the Ligand Docking and Molecular Dynamics Approaches.
Topics: Adenosine Triphosphate; Alendronate; Alkaline Phosphatase; Computational Biology; Diphosphates; Diphosphonates; Enzymes; Humans; Hydrogen Bonding; Ligands; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Pamidronate; Phosphates; Protein Conformation; Thermodynamics; Zoledronic Acid | 2021 |
Atypical femur fracture associated with common anti-osteoporosis drugs in FDA adverse event reporting system.
Topics: Alendronate; Bone Density Conservation Agents; Denosumab; Diphosphonates; Femur; Humans; Ibandronic Acid; Osteoporosis; Pamidronate; Pharmaceutical Preparations; Risedronic Acid | 2023 |