alendronate has been researched along with geranylgeranyl pyrophosphate in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reszka, AA; Rodan, GA | 1 |
| Andela, VB; O'Keefe, RJ; Pirri, M; Puzas, EJ; Rosenblatt, JD; Rosier, RN; Schwarz, EM | 1 |
| Bivi, N; Bonetti, A; Clarke, I; Delneri, D; Harrison, R; Hoyle, DC; Moro, L; Ortolani, F; Quadrifoglio, F; Romanello, M; Tell, G | 1 |
| Crovella, S; De Leo, L; Decorti, G; Marcuzzi, A; Pontillo, A; Tommasini, A | 1 |
| Fujiwara, D; Imano, M; Itoh, T; Komai, M; Mashimo, K; Mukai, J; Nishida, S; Ogawa, N; Sakaguchi, K; Sakamoto, K; Satou, T; Shimaoka, H; Takeda, T; Tsubaki, M | 1 |
| Chen, YN; Mou, Y; Xu, ZX; Yang, J; Zheng, LR | 1 |
2 review(s) available for alendronate and geranylgeranyl pyrophosphate
| Article | Year |
|---|---|
Bisphosphonate mechanism of action.
Topics: Alendronate; Animals; Bone Resorption; Cholesterol; Cytoskeleton; Diphosphonates; Diterpenes; Humans; Lipid Metabolism; Models, Biological; Nitrogen; Osteoclasts; Polyisoprenyl Phosphates; Protein Prenylation | 2002 |
The mevalonate synthesis pathway as a therapeutic target in cancer.
Topics: Acute-Phase Proteins; Alendronate; Alkyl and Aryl Transferases; Animals; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Farnesyltranstransferase; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Mice; Neoplasms; Polyisoprenyl Phosphates; Tumor Cells, Cultured | 2003 |
4 other study(ies) available for alendronate and geranylgeranyl pyrophosphate
| Article | Year |
|---|---|
Identification of secondary targets of N-containing bisphosphonates in mammalian cells via parallel competition analysis of the barcoded yeast deletion collection.
Topics: Alendronate; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Movement; Diphosphonates; DNA Breaks, Double-Stranded; DNA Damage; Etidronic Acid; Gene Deletion; Humans; Ibandronic Acid; Microscopy, Confocal; Microscopy, Electron; Microtubules; Mutation; Polyisoprenyl Phosphates; Risedronic Acid; RNA Interference; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2009 |
The farnesyltransferase inhibitors tipifarnib and lonafarnib inhibit cytokines secretion in a cellular model of mevalonate kinase deficiency.
Topics: Acyclic Monoterpenes; Alendronate; Animals; Anti-Inflammatory Agents; Cell Line; Child; Child, Preschool; Cholesterol; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Farnesyltranstransferase; Humans; Inflammation Mediators; Lovastatin; Male; Mevalonate Kinase Deficiency; Mice; Monocytes; Phosphotransferases (Alcohol Group Acceptor); Piperidines; Polyenes; Polyisoprenyl Phosphates; Polyunsaturated Alkamides; Pyridines; Quinolones; Terpenes | 2011 |
Nitrogen-containing bisphosphonates inhibit RANKL- and M-CSF-induced osteoclast formation through the inhibition of ERK1/2 and Akt activation.
Topics: Alendronate; Animals; Apoptosis; Bone Diseases, Metabolic; Diphosphonates; Humans; Imidazoles; Macrophage Colony-Stimulating Factor; Macrophages; MAP Kinase Signaling System; Mice; Nitrogen; Oncogene Protein v-akt; Osteoclasts; Polyisoprenyl Phosphates; RANK Ligand | 2014 |
Alteration of RhoA Prenylation Ameliorates Cardiac and Vascular Remodeling in Spontaneously Hypertensive Rats.
Topics: Alendronate; Animals; Aorta; Blood Pressure; Bone Density Conservation Agents; Cardiomegaly; Collagen; Echocardiography; Fibrosis; Geranyltranstransferase; Male; Myocardium; Polyisoprenyl Phosphates; Prenylation; Rats, Inbred SHR; Rats, Inbred WKY; rhoA GTP-Binding Protein; Sesquiterpenes; Species Specificity; Vascular Remodeling; Ventricular Remodeling | 2016 |