Compounds > alendronate

alendronate and farnesol

alendronate has been researched along with farnesol in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisher, JE; Halasy, JM; Hughes, DE; Luckman, SP; Masarachia, PJ; Reszka, AA; Rodan, GA; Rogers, MJ; Russell, RG; Wesolowski, G1
Auriola, S; Benford, HL; Frith, JC; Mönkkönen, J; Rogers, MJ1
Phipps, RJ; Scutt, A; Still, K1
Mönkkönen, J; Ollikainen, J; Taskinen, M; Töyräs, A1
De Leo, L; Decorti, G; Marcuzzi, A; Not, T; Pontillo, A; Tommasini, A; Ventura, A1

Other Studies

5 other study(ies) available for alendronate and farnesol

ArticleYear
Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Jan-05, Volume: 96, Issue:1

    Topics: Alendronate; Animals; Bone Resorption; Cell Differentiation; Cells, Cultured; Cholesterol; Clodronic Acid; Diterpenes; Enzyme Activation; Farnesol; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Mice; Osteoclasts; Protein Kinases; Rabbits; Skull; Squalene

1999
Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs.
    Molecular pharmacology, 1999, Volume: 56, Issue:1

    Topics: Adenosine Triphosphate; Alendronate; Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Cells, Cultured; Diphosphonates; Diterpenes; Endopeptidases; Enzyme Activation; Farnesol; Mice; Protein Prenylation

1999
Effects of risedronate, alendronate, and etidronate on the viability and activity of rat bone marrow stromal cells in vitro.
    Calcified tissue international, 2003, Volume: 72, Issue:2

    Topics: Alendronate; Animals; Bone and Bones; Bone Marrow Cells; Cell Survival; Diphosphonates; Diterpenes; Etidronic Acid; Farnesol; Fibroblasts; Models, Animal; Rats; Rats, Wistar; Risedronic Acid; Stromal Cells

2003
Inhibition of mevalonate pathway is involved in alendronate-induced cell growth inhibition, but not in cytokine secretion from macrophages in vitro.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2003, Volume: 19, Issue:4

    Topics: Alendronate; Animals; Cell Division; Cell Line; Diterpenes; Farnesol; Lipopolysaccharides; Macrophages; Mevalonic Acid; Mice

2003
Natural isoprenoids are able to reduce inflammation in a mouse model of mevalonate kinase deficiency.
    Pediatric research, 2008, Volume: 64, Issue:2

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Acyclic Monoterpenes; Alendronate; Animals; Disease Models, Animal; Diterpenes; Farnesol; Inflammation; Male; Mevalonate Kinase Deficiency; Mice; Mice, Inbred BALB C; Terpenes

2008