alendronate and acid phosphatase

alendronate has been researched along with acid phosphatase in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (13.64)18.2507
2000's15 (34.09)29.6817
2010's23 (52.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Clair, J; Davidson, J; Fioravanti, C; Frankenfield, D; Jackson, R; Klein, H; Quartuccio, H; Seedor, JG; Solomon, H; Thompson, DD1
Alfano, FS; Basini, G; Campanini, C; Fantuzzi, M; Gatti, C; Girasole, G; Passeri, M; Pedrazzoni, M1
Balena, R; Frankenfield, D; Klein, H; Lee, SC; Markatos, A; Myers, ER; Opas, EE; Seedor, JG; Shea, M; Toolan, BC1
Fleisch, H; Guenther, HL; Vitté, C1
Chambers, TJ; Fuller, K; Owens, JM1
Apone, S; Eyre, DR; Lee, MY1
Baylink, DJ; Lane, N; Libanati, C; Srivastava, AK1
Alakangas, A; Halleen, J; Lehenkari, P; Mönkkönen, J; Mulari, M; Salo, J; Selander, K; Väänänen, K1
Fisher, JE; Glantschnig, H; Reszka, AA; Rodan, GA; Wesolowski, G1
Al Hadari, A; Blumsohn, A; Clowes, JA; Eagleton, AC; Eastell, R; Hannon, RA1
Bone, A; Destefano, J; Duong, LT; Hayami, T; McLane, J; Pickarski, M; Rodan, GA; Wesolowski, GA1
Azuma, Y; Miyaji, T; Nakase, T; Shimizu, N; Uchiyama, Y; Yoshikawa, H1
Broulik, PD; Rosenkrancová, J; Růzicka, P; Sedlácek, R1
Jhee, O; Kang, J; Kim, D; Kim, T; Lee, B; Lee, JW; Lee, M; Om, A; Park, SK; Yuan, H1
Alatalo, SL; Cheng, S; Halleen, JM; Heinonen, A; Ivaska, KK; Kannus, P; Lehtimäki, T; Nenonen, A; Schmidt-Gayk, H; Sievänen, H; Uusi-Rasi, K; Väänänen, HK; Vuori, I1
Byron, CD1
Nagashima, M; Shu, G; Yamamoto, K1
Marcantonio, E; Marcantonio, RA; Nassar, CA; Nassar, PO; Rossa, C; Spolidorio, DM; Spolidorio, LC1
Gradinger, R; Mehlhorn, AT; Rechl, H; Stemberger, A1
Cheng, S; Fagerlund, KM; Halleen, JM; Janckila, AJ; Nenonen, A; Tiitinen, SL; Uusi-Rasi, K; Väänänen, HK; Yam, LT; Ylipahkala, H1
Manolagas, SC; Roberson, PK; Weinstein, RS1
Hu, Y; Peng, B; Wei, L; Xiong, H; Zhang, C1
Angelucci, A; Avnet, S; Baldini, N; Capulli, M; Castelli, F; Cenni, E; Del Fattore, A; Fotia, C; Giunti, A; Granchi, D; Micieli, D; Pignatello, R; Rucci, N; Salerno, M; Teti, A; Zini, N1
Agholme, F; Aspenberg, P; Fahlgren, A; Magnusson, P1
Bloomfield, SA; Bouse, SD; Hogan, HA; Nilsson, MI; Swift, JM; Swift, SN1
Asuncion, FJ; Barrero, M; Dwyer, D; Grisanti, M; Ke, HZ; Kostenuik, PJ; Li, X; Niu, QT; Ominsky, MS; Paszty, C; Simonet, WS; Stolina, M; Warmington, KS1
Chung, MK; Jung, HS; Kim, JH; Li, Z; Moon, HS; Park, YB; Shim, JS1
Bargman, R; Boskey, AL; DiCarlo, E; Pleshko, N; Posham, R; Raggio, C1
Kawahara, I; Kobayashi, Y; Kurihara, S; Mizoguchi, T; Moriyama, Y; Nakayama, T; Ozawa, H; Sahara, N; Takahashi, N; Udagawa, N; Uehara, S; Yamashita, T1
Chen, H; Kubo, KY; Wu, M1
Arai, K; Endo, N; Kondo, N; Netsu, T; Ogose, A1
Chung, JY; Kim, SE; Lee, DW; Lee, JY; Park, K; Suh, DH; Yun, YP1
Iwasaki, A; Matsui, Y; Minami, Y; Miyake, M; Ohbayashi, Y; Sawai, F1
Arana-Chavez, VE; Bradaschia-Correa, V; Moreira, MM1
Alencar, NM; Benevides, NM; Goes, P; Lima, V; Melo, IM; Ribeiro, RA; Silva, LM1
Liu, L; Liu, M; Liu, W; Shen, J; Shen, Y; Zhang, Q; Zhou, Y1
Amizuka, N; Ideno, H; Komatsu, K; Nakashima, K; Nifuji, A; Noda, M; Shibata, T; Shimada, A; Wada, S1
Gupta, S; Khandelwal, M; Manglani, K; Surolia, A; Vijayan, V1
Abe, Y; Amizuka, N; Chiba, H; Iba, K; Kanaya, K; Kawamata, T; Oda, K; Sasaki, K; Sasaki, M; Yamashita, T1
Chen, K; Ding, L; Hu, J; Zhang, N; Zhang, W; Zhu, S1
Arana-Chavez, VE; Bradaschia-Correa, V; Ferreira, LB; Rothbarth, CP1
Ahmad, N; Gautam, J; Khedgikar, V; Kushwaha, P; Mishra, PR; Nagar, GK; Sangwan, NS; Singh, D; Trivedi, PK; Trivedi, R1
Cui, Z; Li, X; Song, J; Xu, C; Yu, B1
Banfi, G; Congiu, T; Mariotti, M; Pasqualetti, S1

Trials

3 trial(s) available for alendronate and acid phosphatase

ArticleYear
Serum TRACP 5b is a useful marker for monitoring alendronate treatment: comparison with other markers of bone turnover.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2005, Volume: 20, Issue:10

    Topics: Acid Phosphatase; Alendronate; Biomarkers; Bone Density Conservation Agents; Calcium; Double-Blind Method; Drug Monitoring; Female; Humans; Isoenzymes; Middle Aged; Osteogenesis; Postmenopause; Tartrate-Resistant Acid Phosphatase; Vitamin D

2005
Alendronate decreases TRACP 5b activity in osteoarthritic bone.
    European journal of medical research, 2008, Jan-23, Volume: 13, Issue:1

    Topics: Acid Phosphatase; Aged; Alendronate; Bone and Bones; Bone Density Conservation Agents; Cell Count; Female; Femur Head; Humans; Isoenzymes; Male; Middle Aged; Osteoarthritis, Hip; Osteoclasts; Tartrate-Resistant Acid Phosphatase

2008
Giant osteoclast formation and long-term oral bisphosphonate therapy.
    The New England journal of medicine, 2009, Jan-01, Volume: 360, Issue:1

    Topics: Acid Phosphatase; Adult; Alendronate; Apoptosis; Biopsy; Bone and Bones; Bone Density Conservation Agents; Bone Remodeling; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isoenzymes; Linear Models; Middle Aged; Osteoclasts; Postmenopause; Tartrate-Resistant Acid Phosphatase

2009

Other Studies

41 other study(ies) available for alendronate and acid phosphatase

ArticleYear
The bisphosphonate, alendronate, prevents bone loss in ovariectomized baboons.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1992, Volume: 7, Issue:8

    Topics: Acid Phosphatase; Alendronate; Analysis of Variance; Animals; Bone and Bones; Bone Density; Calcium; Diphosphonates; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Female; Humans; Osteocalcin; Osteoporosis, Postmenopausal; Ovariectomy; Papio; Parathyroid Hormone; Radioimmunoassay

1992
Acute effects of bisphosphonates on new and traditional markers of bone resorption.
    Calcified tissue international, 1995, Volume: 57, Issue:1

    Topics: Acid Phosphatase; Aged; Aged, 80 and over; Alendronate; Amino Acids; Biomarkers; Bone and Bones; Bone Resorption; Clodronic Acid; Collagen; Collagen Type I; Diphosphonates; Female; Humans; Hydroxyproline; Injections, Intravenous; Male; Middle Aged; Osteitis Deformans; Osteoporosis; Peptides; Time Factors

1995
The effects of 2-year treatment with the aminobisphosphonate alendronate on bone metabolism, bone histomorphometry, and bone strength in ovariectomized nonhuman primates.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:6

    Topics: Acid Phosphatase; Alendronate; Alkaline Phosphatase; Animals; Biomarkers; Bone and Bones; Calcification, Physiologic; Calcitonin; Calcium; Creatinine; Diphosphonates; Dose-Response Relationship, Drug; Female; Ovariectomy; Papio; Parathyroid Hormone; Phosphates; Reference Values; Tensile Strength; Time Factors

1993
Bisphosphonates induce osteoblasts to secrete an inhibitor of osteoclast-mediated resorption.
    Endocrinology, 1996, Volume: 137, Issue:6

    Topics: Acid Phosphatase; Alendronate; Animals; Bone Resorption; Cell Line; Culture Media, Conditioned; Diphosphonates; Endopeptidases; Hot Temperature; Ibandronic Acid; Isoenzymes; Kinetics; Molecular Weight; Osteoblasts; Osteoclasts; Rats; Rats, Wistar; Tartrate-Resistant Acid Phosphatase

1996
Osteoclast activation: potent inhibition by the bisphosphonate alendronate through a nonresorptive mechanism.
    Journal of cellular physiology, 1997, Volume: 172, Issue:1

    Topics: Acid Phosphatase; Alendronate; Animals; Animals, Newborn; Calcitriol; Cells, Cultured; Mice; Osteoclasts; Rats; Rats, Wistar; Receptors, Calcitonin

1997
Osteoclasts generate cross-linked collagen N-telopeptides (NTx) but not free pyridinolines when cultured on human bone.
    Bone, 1997, Volume: 21, Issue:2

    Topics: Acid Phosphatase; Alendronate; Amino Acids; Animals; Anti-Inflammatory Agents; Biomarkers; Bone Marrow; Bone Resorption; Calcitonin; Calcitriol; Cells, Cultured; Chromatography, High Pressure Liquid; Collagen; Collagen Type I; Culture Media; Dentin; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Femur; Humans; Hydrocortisone; Isoenzymes; Mice; Mice, Inbred BALB C; Osteoclasts; Peptide Biosynthesis; Peptides; Receptors, Calcitonin; Tartrate-Resistant Acid Phosphatase

1997
Development of a synthetic peptide-based tartrate-resistant acid phosphatase radioimmunoassay for the measurement of bone resorption in rat serum.
    Journal of bone and mineral metabolism, 2002, Volume: 20, Issue:2

    Topics: Acid Phosphatase; Alendronate; Animals; Antibodies; Biomarkers; Bone Density; Bone Resorption; Collagen Type I; Estradiol; Female; Ovariectomy; Peptides; Radioimmunoassay; Rats; Rats, Sprague-Dawley

2002
Alendronate disturbs vesicular trafficking in osteoclasts.
    Calcified tissue international, 2002, Volume: 70, Issue:1

    Topics: Acid Phosphatase; Alendronate; Animals; Animals, Newborn; Apoptosis; Biological Transport; Bone and Bones; Bone Resorption; Cattle; In Vitro Techniques; Isoenzymes; Liposomes; Osteoclasts; Rats; Rats, Sprague-Dawley; Tartrate-Resistant Acid Phosphatase; Transport Vesicles

2002
M-CSF, TNFalpha and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase.
    Cell death and differentiation, 2003, Volume: 10, Issue:10

    Topics: Acid Phosphatase; Actins; Adaptor Proteins, Signal Transducing; Alendronate; Alkyl and Aryl Transferases; Animals; Apoptosis; Blotting, Western; Bone Marrow Cells; Bone Resorption; Carrier Proteins; Caspase 3; Caspase 9; Caspases; Cell Cycle Proteins; Cell Survival; Collagen; Collagen Type I; Cytokines; Diterpenes; Enzyme Inhibitors; Eukaryotic Initiation Factors; Immunohistochemistry; Interleukin-1; Isoenzymes; Macrophage Colony-Stimulating Factor; Membrane Glycoproteins; Mice; Models, Biological; NF-kappa B; Osteoclasts; Peptides; Phosphoproteins; Protein Kinases; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Ribosomal Protein S6; Ribosomal Protein S6 Kinases, 70-kDa; Serine-Threonine Kinase 3; Signal Transduction; Sirolimus; Tartrate-Resistant Acid Phosphatase; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha

2003
Clinical performance of immunoreactive tartrate-resistant acid phosphatase isoform 5b as a marker of bone resorption.
    Bone, 2004, Volume: 34, Issue:1

    Topics: Acid Phosphatase; Aged; Alendronate; Biomarkers; Bone Resorption; Calcium; Diet; Female; Humans; Immunoassay; Isoenzymes; Middle Aged; Premenopause; Protein Isoforms; Renal Dialysis; Renal Insufficiency; Reproducibility of Results; Tartrate-Resistant Acid Phosphatase

2004
The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model.
    Arthritis and rheumatism, 2004, Volume: 50, Issue:4

    Topics: Acid Phosphatase; Alendronate; Animals; Anterior Cruciate Ligament; Bone Remodeling; Calcinosis; Cartilage, Articular; Collagen; Collagen Type I; Collagen Type II; Disease Models, Animal; Disease Progression; Extracellular Matrix Proteins; Glycoproteins; Isoenzymes; Male; Matrilin Proteins; Osteoarthritis, Knee; Osteoclasts; Peptides; Rats; Sclerosis; Severity of Illness Index; Tartrate-Resistant Acid Phosphatase; Transforming Growth Factor beta

2004
Alendronate inhibits bone resorption at the bone-screw interface.
    Clinical orthopaedics and related research, 2005, Issue:430

    Topics: Acid Phosphatase; Alendronate; Animals; Bone Resorption; Bone Screws; Cathepsin K; Cathepsins; Disease Models, Animal; External Fixators; Femur; Isoenzymes; Male; Prosthesis Failure; Rats; Rats, Wistar; Tartrate-Resistant Acid Phosphatase

2005
Effect of alendronate administration on bone mineral density and bone strength in castrated rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2005, Volume: 37, Issue:7

    Topics: Acid Phosphatase; Alendronate; Alkaline Phosphatase; Animals; Biomechanical Phenomena; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Calcium; Isoenzymes; Male; Orchiectomy; Organ Size; Osteoclasts; Rats; Seminal Vesicles; Tartrate-Resistant Acid Phosphatase; Tibia

2005
Effect of Korean oriental medicine extract on bone mass as compared with alendronate in ovariectomized rats.
    Journal of medicinal food, 2005,Fall, Volume: 8, Issue:3

    Topics: Acid Phosphatase; Alendronate; Amino Acids; Animals; Biomechanical Phenomena; Bone Density; Bone Remodeling; Bone Resorption; Calcium; Complementary Therapies; Female; Korea; Medicine, Traditional; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; Spine

2005
Role of the osteoclast in cranial suture waveform patterning.
    The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology, 2006, Volume: 288, Issue:5

    Topics: Acid Phosphatase; Age Factors; Aging; Alendronate; Animals; Animals, Newborn; Bone Density Conservation Agents; Bone Development; Bone Remodeling; Bone Resorption; Cell Count; Cell Proliferation; Cranial Sutures; Eating; Food, Formulated; Male; Mice; Mice, Inbred ICR; Osteoclasts; Skull

2006
Differences in osteoclast formation between proximal and distal tibial osteoporosis in rats with adjuvant arthritis: inhibitory effects of bisphosphonates on osteoclasts.
    Modern rheumatology, 2006, Volume: 16, Issue:6

    Topics: Absorptiometry, Photon; Acid Phosphatase; Alendronate; Animals; Arthritis, Experimental; Bone Density; Bone Density Conservation Agents; Bone Marrow Cells; Cells, Cultured; Dose-Response Relationship, Drug; Etidronic Acid; Giant Cells; Isoenzymes; Male; Osteoclasts; Osteoporosis; Rats; Rats, Inbred Lew; Tartrate-Resistant Acid Phosphatase; Tibia

2006
Alendronate therapy in cyclosporine-induced alveolar bone loss in rats.
    Journal of periodontal research, 2007, Volume: 42, Issue:5

    Topics: Acid Phosphatase; Alendronate; Alkaline Phosphatase; Alveolar Bone Loss; Alveolar Process; Animals; Biomarkers; Bone Density; Bone Density Conservation Agents; Calcium; Cell Count; Cyclosporine; Disease Models, Animal; Immunosuppressive Agents; Isoenzymes; Male; Osteoblasts; Osteocalcin; Osteoclasts; Random Allocation; Rats; Rats, Wistar; Tartrate-Resistant Acid Phosphatase

2007
Clinical performance of six different serum tartrate-resistant acid phosphatase assays for monitoring alendronate treatment.
    Clinical laboratory, 2008, Volume: 54, Issue:9-10

    Topics: Acid Phosphatase; Alendronate; Bone Density Conservation Agents; Drug Monitoring; Female; Humans; Immunoenzyme Techniques; Isoenzymes; Postmenopause; Randomized Controlled Trials as Topic; ROC Curve; Tartrate-Resistant Acid Phosphatase

2008
Effect of alendronate on alveolar bone resorption and angiogenesis in rats with experimental periapical lesions.
    International endodontic journal, 2010, Volume: 43, Issue:6

    Topics: Acid Phosphatase; Alendronate; Alveolar Bone Loss; Alveolar Process; Animals; Bone Density Conservation Agents; Bone Resorption; Disease Models, Animal; Drug Administration Schedule; Isoenzymes; Male; Mandible; Microvessels; Neovascularization, Physiologic; Periapical Diseases; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tartrate-Resistant Acid Phosphatase

2010
Bone-targeted doxorubicin-loaded nanoparticles as a tool for the treatment of skeletal metastases.
    Current cancer drug targets, 2010, Volume: 10, Issue:7

    Topics: Acid Phosphatase; Alendronate; Animals; Antineoplastic Agents; Biological Transport; Bone Density Conservation Agents; Bone Neoplasms; Carcinoma; Cell Count; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Female; Humans; Isoenzymes; Mice; Mice, Nude; Nanocapsules; Osteoclasts; Osteolysis; Radiography; Tartrate-Resistant Acid Phosphatase; Xenograft Model Antitumor Assays

2010
Targeting RANKL for reduction of bone loss around unstable implants: OPG-Fc compared to alendronate in a model for mechanically induced loosening.
    Bone, 2011, Volume: 48, Issue:2

    Topics: Acid Phosphatase; Alendronate; Animals; Bone Density Conservation Agents; Bone Plates; Bone Resorption; Immunohistochemistry; Isoenzymes; Male; Osteoprotegerin; Prostheses and Implants; RANK Ligand; Rats; Rats, Sprague-Dawley; Tartrate-Resistant Acid Phosphatase; Tibia

2011
Cancellous bone formation response to simulated resistance training during disuse is blunted by concurrent alendronate treatment.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2011, Volume: 26, Issue:9

    Topics: Acid Phosphatase; Adipocytes; Alendronate; Animals; Apoptosis; Body Weight; Bone and Bones; Cell Count; Hindlimb Suspension; Isoenzymes; Male; Muscle Contraction; Muscular Disorders, Atrophic; Organ Size; Osteocytes; Osteogenesis; Rats; Rats, Sprague-Dawley; Resistance Training; Tarsus, Animal; Tartrate-Resistant Acid Phosphatase

2011
Increased bone formation and bone mass induced by sclerostin antibody is not affected by pretreatment or cotreatment with alendronate in osteopenic, ovariectomized rats.
    Endocrinology, 2011, Volume: 152, Issue:9

    Topics: Acid Phosphatase; Alendronate; Animals; Antibodies, Monoclonal; Bone and Bones; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Bone Morphogenetic Proteins; Disease Models, Animal; Female; Genetic Markers; Isoenzymes; Osteocalcin; Osteogenesis; Ovariectomy; Rats; Rats, Sprague-Dawley; Tartrate-Resistant Acid Phosphatase

2011
Effect of alendronate on healing of extraction sockets and healing around implants.
    Oral diseases, 2011, Volume: 17, Issue:7

    Topics: Acid Phosphatase; Alendronate; Alveolar Bone Loss; Animals; Azo Compounds; Biomarkers; Bone Density Conservation Agents; Collagen Type I; Coloring Agents; Dental Implantation, Endosseous; Dental Implants; Dental Materials; Eosine Yellowish-(YS); Isoenzymes; Male; Maxilla; Methyl Green; Molar; Osseointegration; Osteoclasts; Osteogenesis; Rats; Rats, Sprague-Dawley; Tartrate-Resistant Acid Phosphatase; Time Factors; Titanium; Tooth Extraction; Tooth Socket; Wound Healing

2011
Comparable outcomes in fracture reduction and bone properties with RANKL inhibition and alendronate treatment in a mouse model of osteogenesis imperfecta.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2012, Volume: 23, Issue:3

    Topics: Acid Phosphatase; Alendronate; Animals; Biomechanical Phenomena; Bone Density; Bone Density Conservation Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Isoenzymes; Male; Mice; Osteogenesis Imperfecta; Osteoporotic Fractures; RANK Ligand; Recombinant Fusion Proteins; Tartrate-Resistant Acid Phosphatase; Weight Gain; X-Ray Microtomography

2012
Polarized osteoclasts put marks of tartrate-resistant acid phosphatase on dentin slices--a simple method for identifying polarized osteoclasts.
    Bone, 2011, Volume: 49, Issue:6

    Topics: Acid Phosphatase; Actins; Alendronate; Animals; Bone Resorption; Calcitonin; Cathepsin K; Cell Polarity; Cytological Techniques; Dentin; Isoenzymes; Male; Mice; Osteoclasts; Tartrate-Resistant Acid Phosphatase; Vacuolar Proton-Translocating ATPases

2011
Combined treatment with a traditional Chinese medicine, Hachimi-jio-gan (Ba-Wei-Di-Huang-Wan) and alendronate improves bone microstructure in ovariectomized rats.
    Journal of ethnopharmacology, 2012, Jun-26, Volume: 142, Issue:1

    Topics: Acid Phosphatase; Alendronate; Animals; Bone Density Conservation Agents; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Isoenzymes; Lumbar Vertebrae; Medicine, Chinese Traditional; Osteocalcin; Osteogenesis; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; Tartrate-Resistant Acid Phosphatase; Tibia

2012
Osteoconductive action of alendronate after implantation of beta tricalcium phosphate in rat adjuvant-induced arthritis.
    Journal of bone and mineral metabolism, 2012, Volume: 30, Issue:6

    Topics: Acid Phosphatase; Alendronate; Animals; Arthritis, Experimental; Calcification, Physiologic; Calcium Phosphates; Collagen Type I; Collagen Type I, alpha 1 Chain; Isoenzymes; Male; Osteocalcin; Osteogenesis; Rats; Tartrate-Resistant Acid Phosphatase

2012
Local delivery of alendronate eluting chitosan scaffold can effectively increase osteoblast functions and inhibit osteoclast differentiation.
    Journal of materials science. Materials in medicine, 2012, Volume: 23, Issue:11

    Topics: Acid Phosphatase; Alendronate; Animals; Base Sequence; Bone Density Conservation Agents; Cell Differentiation; Cell Line; Chitosan; DNA Primers; Drug Carriers; Isoenzymes; Mice; Microscopy, Electron, Scanning; NFATC Transcription Factors; Osteoblasts; Osteoclasts; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tartrate-Resistant Acid Phosphatase

2012
Adjunct teriparatide therapy with monitoring of bone turnover markers and bone scintigraphy for bisphosphonate-related osteonecrosis of the jaw.
    Oral surgery, oral medicine, oral pathology and oral radiology, 2013, Volume: 115, Issue:4

    Topics: Acid Phosphatase; Aged; Alendronate; Alkaline Phosphatase; Amino Acids; Biomarkers; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Bone Regeneration; Bone Resorption; Collagen Type I; Female; Follow-Up Studies; Humans; Isoenzymes; Mandible; Mandibular Diseases; Osteocalcin; Osteogenesis; Peptide Fragments; Peptides; Procollagen; Radionuclide Imaging; Radiopharmaceuticals; Tartrate-Resistant Acid Phosphatase; Technetium Tc 99m Medronate; Teriparatide

2013
Reduced RANKL expression impedes osteoclast activation and tooth eruption in alendronate-treated rats.
    Cell and tissue research, 2013, Volume: 353, Issue:1

    Topics: Acid Phosphatase; Alendronate; Animals; Bone Density Conservation Agents; Bone Resorption; Cell Differentiation; Dental Sac; Isoenzymes; Osteoclasts; Osteoprotegerin; RANK Ligand; Rats; Rats, Wistar; Receptor Activator of Nuclear Factor-kappa B; Tartrate-Resistant Acid Phosphatase; Tooth Eruption

2013
Low-dose combination of alendronate and atorvastatin reduces ligature-induced alveolar bone loss in rats.
    Journal of periodontal research, 2014, Volume: 49, Issue:1

    Topics: Acid Phosphatase; Alanine Transaminase; Alendronate; Alkaline Phosphatase; Alveolar Bone Loss; Animals; Aspartate Aminotransferases; Atorvastatin; Body Weight; Bone Density Conservation Agents; Dental Cementum; Gingiva; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infusions, Parenteral; Injections, Subcutaneous; Isoenzymes; Leukocyte Disorders; Leukocytes; Leukocytosis; Male; Monocytes; Neutrophils; Peroxidase; Pyrroles; Rats, Wistar; Root Resorption; Tartrate-Resistant Acid Phosphatase

2014
The effect of alendronate on the expression of important cell factors in osteoclasts.
    Molecular medicine reports, 2013, Volume: 8, Issue:4

    Topics: Acid Phosphatase; Alendronate; Animals; Bone Density Conservation Agents; Carbonic Anhydrase II; Cell Line; Cell Nucleus; Cell Size; Fas Ligand Protein; fas Receptor; Gene Expression; Isoenzymes; Mice; Osteoclasts; RANK Ligand; Receptors, Cell Surface; Tartrate-Resistant Acid Phosphatase

2013
Alendronate promotes bone formation by inhibiting protein prenylation in osteoblasts in rat tooth replantation model.
    The Journal of endocrinology, 2013, Volume: 219, Issue:2

    Topics: Acid Phosphatase; Alendronate; Alkaline Phosphatase; Animals; Bone Density Conservation Agents; Cell Differentiation; Cell Line; Cell Proliferation; In Vitro Techniques; Isoenzymes; Models, Animal; Osteoblasts; Osteocalcin; Osteogenesis; Protein Prenylation; Rats; Tartrate-Resistant Acid Phosphatase; Tooth Replantation

2013
Methionine down-regulates TLR4/MyD88/NF-κB signalling in osteoclast precursors to reduce bone loss during osteoporosis.
    British journal of pharmacology, 2014, Volume: 171, Issue:1

    Topics: Acid Phosphatase; Administration, Oral; Alendronate; Animals; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Cells, Cultured; Chemokine CCL3; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Therapy, Combination; Female; Inflammation Mediators; Isoenzymes; Methionine; Myeloid Differentiation Factor 88; NF-kappa B; Osteoclasts; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; RNA Interference; Signal Transduction; Tartrate-Resistant Acid Phosphatase; Time Factors; Toll-Like Receptor 4

2014
Inhibitory effect of bisphosphonate on osteoclast function contributes to improved skeletal pain in ovariectomized mice.
    Journal of bone and mineral metabolism, 2015, Volume: 33, Issue:2

    Topics: Acid Phosphatase; Alendronate; Animals; Diphosphonates; Disease Models, Animal; Female; Isoenzymes; Mice; Mice, Inbred C57BL; Osteoclasts; Osteoporosis; Ovariectomy; Pain; Pain Threshold; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Tartrate-Resistant Acid Phosphatase; Transient Receptor Potential Channels

2015
Early intra-articular injection of alendronate reduces cartilage changes and subchondral bone loss in rat temporomandibular joints after ovariectomy.
    International journal of oral and maxillofacial surgery, 2014, Volume: 43, Issue:8

    Topics: Acid Phosphatase; Alendronate; Animals; Cartilage; Female; Immunoenzyme Techniques; Injections, Intra-Articular; Isoenzymes; Mandibular Condyle; Ovariectomy; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Tartrate-Resistant Acid Phosphatase; Temporomandibular Joint; X-Ray Microtomography

2014
Effects of the bisphosphonate alendronate on molars of young rats after lateral luxation.
    Dental traumatology : official publication of International Association for Dental Traumatology, 2014, Volume: 30, Issue:6

    Topics: Acid Phosphatase; Alendronate; Alveolar Process; Animals; Bone Density Conservation Agents; Dental Cementum; Dentin; Female; Isoenzymes; Male; Microscopy, Electron, Transmission; Molar; Odontogenesis; Osteoclasts; Osteopontin; Periodontium; Rats; Rats, Wistar; Root Resorption; Tartrate-Resistant Acid Phosphatase; Time Factors; Tooth Ankylosis; Tooth Apex; Tooth Avulsion; Tooth Root

2014
Preventive effects of withaferin A isolated from the leaves of an Indian medicinal plant Withania somnifera (L.): comparisons with 17-β-estradiol and alendronate.
    Nutrition (Burbank, Los Angeles County, Calif.), 2015, Volume: 31, Issue:1

    Topics: Acid Phosphatase; Alendronate; Animals; Biomarkers; Bone and Bones; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Estradiol; Female; Isoenzymes; Mice; Mice, Inbred BALB C; Osteocalcin; Osteoclasts; Osteoporosis; Ovariectomy; Plant Leaves; Plants, Medicinal; Receptor Activator of Nuclear Factor-kappa B; Tartrate-Resistant Acid Phosphatase; Tumor Necrosis Factor-alpha; Withania; Withanolides

2015
Treatment with recombinant lubricin attenuates osteoarthritis by positive feedback loop between articular cartilage and subchondral bone in ovariectomized rats.
    Bone, 2015, Volume: 74

    Topics: Acid Phosphatase; Alendronate; Animals; Cartilage, Articular; Collagen Type I; Collagen Type X; Feedback, Physiological; Female; Glycoproteins; Humans; Isoenzymes; Matrix Metalloproteinase 13; Osteoarthritis; Ovariectomy; Peptides; Platelet Endothelial Cell Adhesion Molecule-1; Protective Agents; Rats, Sprague-Dawley; Recombinant Proteins; Tartrate-Resistant Acid Phosphatase; Tibia; Transcription Factors; X-Ray Microtomography

2015
Alendronate rescued osteoporotic phenotype in a model of glucocorticoid-induced osteoporosis in adult zebrafish scale.
    International journal of experimental pathology, 2015, Volume: 96, Issue:1

    Topics: Acid Phosphatase; Alendronate; Alkaline Phosphatase; Animals; Biomarkers; Bone Density Conservation Agents; Bone Matrix; Bone Remodeling; Disease Models, Animal; Glucocorticoids; Isoenzymes; Male; Osteoclasts; Osteoporosis; Phenotype; Prednisolone; Tartrate-Resistant Acid Phosphatase; Time Factors; Tissue Culture Techniques; Zebrafish; Zebrafish Proteins

2015