aldrin and titanium-dioxide

Aldrin (ALD), a persistent-organic-pollutant (POP), an organochlorine-cyclodiene-pesticide is highly toxic in nature. Titanium dioxide nanoparticles (TNP) are widely used for various industrial applications. Despite the remarkable research on pesticide toxicity, the work with impact of nanoparticles on POP has been dealt with marginally. Chemicals co-exist in the environment and exhibit interactive effects. An investigation was carried out to evaluate the individual and combined effects of ALD (6 ppm) and TNP (60 ppm) exposure at sub-lethal concentration for 24 h in zebrafish. Significant reversal of lipid peroxidation level in liver and brain tissues and restoration in enhanced catalase activity in all examined tissues were observed in combined group. For other parameters, combined exposure of ALD and TNP does not show significant reversal action on ALD toxicity. Further studies are inline to understand combined effects of both to achieve significant reversal of ALD toxicity by TNP nanoparticles with threshold concentration of aldrin.

Topics: Aldrin; Animals; Brain; Catalase; Drug Interactions; Gene Expression; Glutathione; Glutathione Peroxidase; Insecticides; Kidney; Lipid Peroxidation; Liver; Malondialdehyde; Nanoparticles; Superoxide Dismutase; Titanium; Water Pollutants, Chemical; Zebrafish

Suspended particulates collected in Yokohama, Japan over various 24-h periods were found to cause the photochemical epoxidation of aldrin to dieldrin in good yield. trans-Stilbene did not undergo the epoxidation. Upon irradiation of aldrin together with the suspended particulates in quasi-air consisting of 18O2. 100% incorporation of 18O into dieldrin was obtained. Thus, the oxygen atom in dieldrin originated not from the particulates, but from oxygen in air.

Topics: Air Pollutants; Aldrin; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Lead; Nitrates; Oxides; Photochemistry; Spectrometry, Fluorescence; Sulfates; Suspensions; Titanium; Zinc Oxide