Page last updated: 2024-08-17

aldosterone and transforming growth factor beta

aldosterone has been researched along with transforming growth factor beta in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (7.94)	18.2507
2000's	41 (65.08)	29.6817
2010's	15 (23.81)	24.3611
2020's	2 (3.17)	2.80

Authors

Authors	Studies
Franco-Saenz, R; Gentry, LE; Gupta, P; Mulrow, PJ	1
Husted, RF; Matsushita, K; Stokes, JB	1
Franco-Saenz, R; Gupta, P; Mulrow, PJ	1
Husted, RF; Stokes, JB	1
Chambaz, EM; Defaye, G; Feige, JJ; Galtier, A; Keramidas, M; Liakos, P	1
Husted, RF; Sigmund, RD; Stokes, JB	1
Stokes, JB	1
Ramires, FJ; Sun, Y; Zhang, J; Zhang, JQ	1
Chai, Q; Hermans, C; Krag, S; Nielsen, CB; Osterby, R; Wogensen, L	1
Bieringer, M; Breu, V; Dechend, R; Fiebeler, A; Haller, H; Luft, FC; Müller, DN; Park, JK; Schmidt, F; Shagdarsuren, E	1
Berrou, J; Hertig, A; Rerolle, JP; Rondeau, E; Vigneau, C	1
Kangawa, K; Kobayashi, N; Matsuoka, H; Mori, Y; Nishikimi, T; Ono, H	1
Border, WA; Gaedeke, J; Noble, NA	1
Bobadilla, NA; Feria, I; Gamba, G; García-Torres, R; González, MA; Juárez, P; López-Casillas, F; Pichardo, I; Ramírez, V; Uribe, N	1
Bernhardt, R; Defaye, G; Feige, JJ; Lenz, D; Liakos, P	1
Bloem, LJ; Chun, TY; Pratt, JH	1
Kessler, E; Kessler-Icekson, G; Levy, MJ; Schlesinger, H; Shalitin, N	1
Barty, MM; Carlesso, G; Davidson, JM; Fogo, AB; Gaspert, A; Ma, LJ; Sheppard, D; Yang, H	1
de Boer, RA; de Borst, MH; Huitema, S; Navis, G; van Gilst, WH; van Goor, H; Vis, LM	1
Hostetter, TH; Juknevicius, I; Kren, S; Lee, R; Segal, Y	1
Aizawa, T; Ishizaka, N; Iso-o, N; Mori, I; Nagai, R; Noiri, E; Ohno, M; Saito, K; Sata, M	1
González-Núñez, D; Natarajan, R; Poch, E; Solé, M	1
Kurabayashi, M	1
Chun, TY; Pratt, JH	1
Cockwell, P; Eardley, KS; Hewison, M; Howie, AJ; Hughes, SV; Lepenies, J; Quinkler, M; Stewart, PM; Zehnder, D	1
Chen, YP; Luo, Y	1
Kobayashi, N; Matsuoka, H; Nakano, S; Ohno, T; Yoshida, K	1
Abe, Y; Baba, R; Fan, YY; Fujita, M; Hosomi, N; Kimura, S; Kohno, M; Miyatake, A; Nagai, Y; Nishiyama, A; Sun, GP	1
Asano, Y; Fujita, M; Hirata, A; Hori, M; Kitakaze, M; Minamino, T; Okada, K; Sanada, S; Shintani, Y; Takashima, S; Tomoike, H; Tsukamoto, O; Yamasaki, S; Yulin, L	1
Abe, Y; Fan, YY; Guo, P; Kimura, S; Kiyomoto, H; Kohno, M; Li, DT; Miyata, K; Nagai, Y; Nishiyama, A; Ohmori, K; Sun, GP	1
Hirata, A; Igarashi, M; Kadomoto, Y; Tominaga, M	1
Chen, J; Gu, Y; Hao, CM; Lai, L; Lin, S	1
Kitamura, K; Tomita, K	1
Akdag, I; Filiz, G; Gullulu, M; Kahvecioglu, S; Savci, V	1
Adachi, M; Ha, V; Kitamura, K; Ko, T; Maekawa, A; Miyoshi, T; Nonoguchi, H; Shiraishi, N; Tomita, K; Tuyen, DG; Wakida, N	1
Demer, LL; Jaffe, IZ; Mendelsohn, ME; Newfell, BG; Tintut, Y	1
Inagaki, K; Makino, H; Miyoshi, T; Mukai, T; Ogura, T; Otani, H; Otsuka, F; Suzuki, J; Takeda, M	1
Fujita, T; Goto, A; Kobayashi, N; Matsuoka, H; Onozato, ML; Tojo, A	1
Adrogue, HJ; Huang, XR; Lan, HY; Soltero, L; Wang, W; Zhang, P	1
Chatziantoniou, C; Dussaule, JC	1
Siragy, HM; Xue, C	1
Chander, PN; Chun, TY; Kim, JW; Pratt, JH; Stier, CT	1
Carvajal, CA; Castillo, CR; Contreras, FJ; Fardella, CE; Herrada, AA; Kalergis, AM; Mosso, LM; Stehr, CB	1
Armanini, D; Calò, LA; Davis, PA; Mormino, P; Pagnin, E; Pessina, AC; Rossi, GP	1
Du, J; Fan, YY; Fu, H; Fujisawa, Y; Hitomi, H; Hosomi, N; Kimura, S; Kiyomoto, H; Kohno, M; Lu, XM; Nagai, Y; Nakano, D; Nishiyama, A; Ohmori, K	1
Beineke, A; Hosten, N; Maschke, U; Mullins, JJ; Peters, BS; Peters, J; Rettig, R; Riegel, T; Schlüter, T	1
Hayashi, T; Kimura, S; Kitada, K; Kitaura, Y; Kobayashi, K; Kurumazuka, D; Matsuda, H; Matsumoto, C; Matsumura, Y; Mori, T; Shirakawa, H	1
Díez, J; González, A; López, B	1
Casarini, DE; Coelho, MS; Ferreira, DN; Furukawa, LN; Heimann, JC; Katayama, IA; Oliveira, IB; Rosa, KT	1
Fujita, H; Harasawa, S; Hirayama, A; Koike, M; Kushiro, T; Nagao, K; Okubo, K; Otsuka, Y	1
Blessing, M; Gekle, M; Grossmann, C; Hauptmann, S; Neumann, J; Rabe, S; Ruhs, S; Schneider, B; Schreier, B	1
Chan, LY; Chow, CW; Lai, KN; Lam, MF; Leung, JC; Lim, AI; Tang, SC	1
Bollag, WB; Nishimoto, K; Rainey, WE; Seki, T	1
Chang, JW; Kim, JH; Kim, JS; Kim, SB; Lee, JH; Lee, SK; Park, JS	1
Day, EC; Shlipak, MG	1
Dai, Z; He, H; Huang, C; Meng, Y; Tang, Y; Wang, X; Xiao, J; Yu, S; Zhao, Q	1
Geier, A; Happ, K; Jahn, D; Link, S; Queisser, N; Schupp, N; Zimnol, A	1
Azizan, EA; Brighton, CA; Brown, MJ; Figg, N; Maniero, C; McFarlane, I; Neogi, SG; Shaikh, LH; Teo, AE; Zhao, W; Zhou, J	1
Albertini, R; Avanzini, MA; Bedino, G; Corradetti, V; Dal Canton, A; Esposito, P; Gregorini, M; Ingo, D; Libetta, C; Mantelli, M; Milanesi, S; Pattonieri, EF; Peressini, S; Rampino, T; Rocca, C; Serpieri, N; Valsania, T	1
Donderski, R; Grajewska, M; Manitius, J; Miśkowiec, I; Odrowąż-Sypniewska, G; Siódmiak, J; Stefańska, A; Stróżecki, P; Sulikowska, B	1
Gong, H; Li, H; Lu, Y; Ma, X; Wang, B; Wang, C; Wu, Z; Yan, Y; Zhang, X	1
Aljohmani, AI; Alzoubi, KH; Mayyas, FA	1
Armani, A; Caprio, M; Cecconi, F; De Zio, D; Filippini, A; Giampietri, C; Mammi, C; Mandatori, S; Marzolla, V; Pacella, I; Padula, F; Piconese, S; Savoia, C; Starace, D; Taurino, M; Vitiello, L	1

Reviews

8 review(s) available for aldosterone and transforming growth factor beta

Article	Year
Physiologic resistance to the action of aldosterone. Kidney international, 2000, Volume: 57, Issue:4 Topics: Aldosterone; Animals; Drug Resistance; Hormones; Kidney Medulla; Kidney Tubules, Collecting; Transforming Growth Factor beta	2000
[Plasminogen activator inhibitor type 1: physiology and role in renal physiopathology]. Nephrologie, 2001, Volume: 22, Issue:1 Topics: Aldosterone; Fibrinolysis; Fibrosis; Humans; Kidney; Kidney Diseases; Kidney Transplantation; Plasminogen Activator Inhibitor 1; Renin-Angiotensin System; Transforming Growth Factor beta	2001
Angiotensin II and progressive renal insufficiency. Current hypertension reports, 2002, Volume: 4, Issue:5 Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Endothelins; Humans; Kidney Failure, Chronic; Plasminogen Activator Inhibitor 1; Receptors, Angiotensin; Transforming Growth Factor beta	2002
[PPARs and fibrosis]. Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63, Issue:4 Topics: Adipocytes; Aldosterone; Animals; Connective Tissue Growth Factor; Fibrosis; Immediate-Early Proteins; Inflammation; Intercellular Signaling Peptides and Proteins; Mice; NADPH Oxidases; Peroxisome Proliferator-Activated Receptors; Transforming Growth Factor beta	2005
[Prostasin]. Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 5 Topics: Aldosterone; Amyloid beta-Protein Precursor; Animals; Benzamidines; Epithelial Sodium Channels; Guanidines; Humans; Hypertension; Immediate-Early Proteins; Membrane Glycoproteins; Protease Nexins; Protein Serine-Threonine Kinases; Receptors, Cell Surface; Serine Endopeptidases; Serine Proteinase Inhibitors; Sodium Channels; Transforming Growth Factor beta; Trypsin Inhibitor, Kunitz Soybean	2006
Is kidney injury a reversible process? Current opinion in nephrology and hypertension, 2008, Volume: 17, Issue:1 Topics: Aldosterone; Animals; Extracellular Matrix; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Diseases; Receptors, Cell Surface; Transforming Growth Factor beta	2008
Lessons from the gene expression pattern of the rat zona glomerulosa. Molecular and cellular endocrinology, 2013, May-22, Volume: 371, Issue:1-2 Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Calcium; Cardiovascular Diseases; Gene Expression; Potassium; Rats; Signal Transduction; Transcription, Genetic; Transforming Growth Factor beta; Wnt Proteins; Zona Fasciculata; Zona Glomerulosa	2013
Biomarkers for incident CKD: a new framework for interpreting the literature. Nature reviews. Nephrology, 2013, Volume: 9, Issue:8 Topics: Acute-Phase Proteins; Aldosterone; Biomarkers; Connective Tissue Growth Factor; Creatinine; Cystatin C; Genetic Markers; Genetic Predisposition to Disease; Glomerular Filtration Rate; Hepatitis A Virus Cellular Receptor 1; Homocysteine; Humans; Lipocalin-2; Lipocalins; Membrane Glycoproteins; Peptides; Proto-Oncogene Proteins; Receptors, Virus; Renal Insufficiency, Chronic; Risk Factors; Transforming Growth Factor beta; Trefoil Factor-3; Uromodulin	2013

Trials

1 trial(s) available for aldosterone and transforming growth factor beta

Article	Year
Dual blockade of angiotensin II with enalapril and losartan reduces proteinuria in hypertensive patients with type 2 diabetes. Endocrine journal, 2006, Volume: 53, Issue:4 Topics: Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; C-Reactive Protein; Cystatin C; Cystatins; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enalapril; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Natriuretic Peptide, Brain; Proteinuria; Transforming Growth Factor beta	2006

Article

Year

Dual blockade of angiotensin II with enalapril and losartan reduces proteinuria in hypertensive patients with type 2 diabetes.

Endocrine journal, 2006, Volume: 53, Issue:4

Topics: Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; C-Reactive Protein; Cystatin C; Cystatins; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enalapril; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Natriuretic Peptide, Brain; Proteinuria; Transforming Growth Factor beta

2006

Other Studies

54 other study(ies) available for aldosterone and transforming growth factor beta

Article	Year
Transforming growth factor-beta 1 inhibits aldosterone and stimulates adrenal renin in cultured bovine zona glomerulosa cells. Endocrinology, 1992, Volume: 131, Issue:2 Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Bucladesine; Cattle; Cells, Cultured; Cyclic AMP; Enzyme Precursors; Mineralocorticoid Receptor Antagonists; Renin; Transforming Growth Factor beta; Zona Glomerulosa	1992
Induction of resistance to mineralocorticoid hormone in cultured inner medullary collecting duct cells by TGF-beta 1. The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aldosterone; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Biological Transport; Cells, Cultured; DNA; Drug Resistance; Endothelins; Epidermal Growth Factor; Female; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Insulin-Like Growth Factor I; Kidney Medulla; Kidney Tubules, Collecting; Kinetics; Nerve Growth Factors; Platelet-Derived Growth Factor; Radioisotope Dilution Technique; Rats; Rats, Wistar; Sodium; Sodium Radioisotopes; Time Factors; Transforming Growth Factor beta	1994
Transforming growth factor-beta 1 inhibits aldosterone biosynthesis in cultured bovine zona glomerulosa cells. Endocrinology, 1993, Volume: 132, Issue:3 Topics: Aldosterone; Angiotensin II; Animals; Cattle; Cell Survival; Cells, Cultured; Corticosterone; Desoxycorticosterone; Kinetics; Mineralocorticoid Receptor Antagonists; Potassium; Pregnenolone; Transforming Growth Factor beta; Zona Glomerulosa	1993
Separate regulation of Na+ and anion transport by IMCD: location, aldosterone, hypertonicity, TGF-beta 1, and cAMP. The American journal of physiology, 1996, Volume: 271, Issue:2 Pt 2 Topics: Absorption; Aldosterone; Animals; Anions; Biological Transport; Cells, Cultured; Chlorides; Cyclic AMP; Female; Hypertonic Solutions; Kidney Medulla; Kidney Tubules, Collecting; Rats; Rats, Wistar; Sodium; Tissue Distribution; Transforming Growth Factor beta	1996
ACTH angiotensin II and TGF beta participate in the regulation of steroidogenesis in bovine adrenal glomerulosa cells. Endocrine research, 1996, Volume: 22, Issue:4 Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Cattle; Cell Differentiation; Cells, Cultured; Cytochrome P-450 CYP11B2; Hydrocortisone; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Transforming Growth Factor beta; Zona Glomerulosa	1996
Mechanisms of inactivation of the action of aldosterone on collecting duct by TGF-beta. American journal of physiology. Renal physiology, 2000, Volume: 278, Issue:3 Topics: Aldosterone; Amiloride; Animals; Cells, Cultured; Drug Interactions; Epithelial Sodium Channels; Glucocorticoids; Kidney Tubules, Collecting; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Rats; Rats, Wistar; RNA, Messenger; Sodium; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Transforming Growth Factor beta	2000
Local angiotensin II and transforming growth factor-beta1 in renal fibrosis of rats. Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:5 Topics: Aldosterone; Angiotensin II; Animals; Kidney Diseases; Male; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Transforming Growth Factor beta	2000
TGF-beta1-induced glomerular disorder is associated with impaired concentrating ability mimicking primary glomerular disease with renal failure in man. Laboratory investigation; a journal of technical methods and pathology, 2000, Volume: 80, Issue:12 Topics: Aldosterone; Animals; Aquaporin 2; Aquaporin 6; Aquaporins; Circadian Rhythm; Disease Models, Animal; Diuresis; Female; Glomerular Filtration Rate; Humans; Juxtaglomerular Apparatus; Kidney Failure, Chronic; Kidney Glomerulus; Male; Mice; Mice, Transgenic; Promoter Regions, Genetic; Reference Values; Swine; Transforming Growth Factor beta	2000
Mineralocorticoid receptor affects AP-1 and nuclear factor-kappab activation in angiotensin II-induced cardiac injury. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2 Topics: Aldosterone; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Body Weight; Cardiovascular Diseases; Fibroblast Growth Factor 2; Heart; Immunohistochemistry; Mineralocorticoid Receptor Antagonists; NF-kappa B; Organ Size; Platelet-Derived Growth Factor; Rats; Receptors, Mineralocorticoid; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spironolactone; Tetrazoles; Transcription Factor AP-1; Transforming Growth Factor beta; Valine; Valsartan	2001
Long-term adrenomedullin infusion improves survival in malignant hypertensive rats. Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:1 Topics: Adrenomedullin; Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Weight; Desoxycorticosterone; Heart Rate; Humans; Hypertension, Malignant; Infusion Pumps; Injections, Subcutaneous; Kidney; Male; Organ Size; Peptides; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; RNA, Messenger; Survival Rate; Time Factors; Transforming Growth Factor beta; Vasodilator Agents	2002
Therapeutic benefit of spironolactone in experimental chronic cyclosporine A nephrotoxicity. Kidney international, 2003, Volume: 63, Issue:1 Topics: Aldosterone; Animals; Chronic Disease; Collagen Type I; Collagen Type IV; Cyclosporine; Fibronectins; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; RNA, Messenger; Spironolactone; Transforming Growth Factor beta; Transforming Growth Factor beta1	2003
Transforming growth factor beta1 inhibits aldosterone and cortisol production in the human adrenocortical cell line NCI-H295R through inhibition of CYP11B1 and CYP11B2 expression. The Journal of endocrinology, 2003, Volume: 176, Issue:1 Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Analysis of Variance; Androstenedione; Angiotensin II; Colforsin; Corticosterone; Cortodoxone; Cytochrome P-450 CYP11B2; Depression, Chemical; Humans; Hydrocortisone; RNA, Messenger; Steroid 11-beta-Hydroxylase; Transforming Growth Factor beta; Tumor Cells, Cultured	2003
Aldosterone inhibits inducible nitric oxide synthase in neonatal rat cardiomyocytes. Endocrinology, 2003, Volume: 144, Issue:5 Topics: Aldosterone; Animals; Animals, Newborn; Cells, Cultured; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucocorticoids; Mineralocorticoid Receptor Antagonists; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spironolactone; Transforming Growth Factor beta; Transforming Growth Factor beta1	2003
Expression of procollagen C-proteinase enhancer in cultured rat heart fibroblasts: evidence for co-regulation with type I collagen. Journal of cellular biochemistry, 2003, Oct-01, Volume: 90, Issue:2 Topics: Aldosterone; Animals; Antioxidants; Ascorbic Acid; Blotting, Northern; Blotting, Western; Bone Morphogenetic Protein 1; Bone Morphogenetic Proteins; Cells, Cultured; Collagen Type I; Fibroblasts; Gene Expression Regulation; Glycoproteins; Heart; Intercellular Signaling Peptides and Proteins; Metalloendopeptidases; Procollagen; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta	2003
Transforming growth factor-beta-dependent and -independent pathways of induction of tubulointerstitial fibrosis in beta6(-/-) mice. The American journal of pathology, 2003, Volume: 163, Issue:4 Topics: Aldosterone; Animals; Antigens, Neoplasm; Blood Pressure; DNA-Binding Proteins; Fibrosis; Integrins; Kidney Diseases; Kidney Tubules; Male; Mice; Mice, Knockout; Plasminogen Activator Inhibitor 1; Renin-Angiotensin System; Smad2 Protein; Systole; Thrombospondin 1; Tissue Distribution; Trans-Activators; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ureteral Obstruction	2003
Specific MAP-kinase blockade protects against renal damage in homozygous TGR(mRen2)27 rats. Laboratory investigation; a journal of technical methods and pathology, 2003, Volume: 83, Issue:12 Topics: Actins; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Desmin; Enzyme Inhibitors; Glomerular Mesangium; Homozygote; Imidazoles; Kidney Diseases; Male; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyrimidines; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrphostins	2003
Effect of aldosterone on renal transforming growth factor-beta. American journal of physiology. Renal physiology, 2004, Volume: 286, Issue:6 Topics: Aldosterone; Angiotensin I; Animals; Blood Pressure; Body Weight; Drug Implants; Gene Expression Regulation; Kidney; Male; Nuclease Protection Assays; Rats; Rats, Sprague-Dawley; Renin; Stimulation, Chemical; Transforming Growth Factor beta; Water-Electrolyte Balance	2004
Iron chelation and a free radical scavenger suppress angiotensin II-induced upregulation of TGF-beta1 in the heart. American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:4 Topics: Aldosterone; Angiotensin II; Animals; Chemokine CCL2; Deferoxamine; Enzyme Inhibitors; Ferritins; Fibrosis; Free Radical Scavengers; Gene Expression; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Iron; Iron Chelating Agents; Male; Myocardium; Oxidative Stress; Phenylurea Compounds; Protoporphyrins; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation; Vasoconstrictor Agents	2005
12-Lipoxygenase metabolism in mouse distal convoluted tubule cells. Kidney international, 2005, Volume: 67, Issue:1 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Aldosterone; Angiotensin II; Animals; Arachidonate 12-Lipoxygenase; Base Sequence; Blood Platelets; Cell Line; DNA; Gene Expression Regulation, Enzymologic; Humans; Kidney Tubules, Distal; Leukocytes; Mice; RNA, Messenger; Transforming Growth Factor beta	2005
Aldosterone increases plasminogen activator inhibitor-1 synthesis in rat cardiomyocytes. Molecular and cellular endocrinology, 2005, Jul-15, Volume: 239, Issue:1-2 Topics: Aldosterone; Animals; Cell Line; Gene Expression Regulation; Mineralocorticoid Receptor Antagonists; Myocytes, Cardiac; Plasminogen Activator Inhibitor 1; Rats; Spironolactone; Transforming Growth Factor beta; Transforming Growth Factor beta1	2005
Increased expression of mineralocorticoid effector mechanisms in kidney biopsies of patients with heavy proteinuria. Circulation, 2005, Sep-06, Volume: 112, Issue:10 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Biopsy; Blood Pressure; Chemokine CCL2; Female; Glomerular Basement Membrane; Humans; Immediate-Early Proteins; Interleukin-6; Ischemia; Kidney; Kidney Function Tests; Male; Middle Aged; Protein Serine-Threonine Kinases; Proteinuria; Receptors, Mineralocorticoid; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1	2005
[The effect of tubular epithelial cells activated by aldosterone on renal interstitial fibroblasts in co-culture system]. Zhonghua yi xue za zhi, 2005, Aug-03, Volume: 85, Issue:29 Topics: Aldosterone; Coculture Techniques; Collagen Type I; Endothelin-1; Epithelial Cells; Fibroblasts; Humans; Kidney Tubules, Proximal; Transforming Growth Factor beta	2005
Cardioprotective mechanisms of spironolactone associated with the angiotensin-converting enzyme/epidermal growth factor receptor/extracellular signal-regulated kinases, NAD(P)H oxidase/lectin-like oxidized low-density lipoprotein receptor-1, and Rho-kinas Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:11 Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Chemokine CCL2; Coronary Vessels; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fibrillar Collagens; Gene Expression; Heart Ventricles; Hypertension; Imidazolidines; Intracellular Signaling Peptides and Proteins; Male; Mineralocorticoid Receptor Antagonists; NADPH Oxidases; Peptidyl-Dipeptidase A; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; rho-Associated Kinases; rhoA GTP-Binding Protein; Scavenger Receptors, Class E; Signal Transduction; Sodium Chloride; Spironolactone; Transforming Growth Factor beta; Transforming Growth Factor beta1	2005
Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan. Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:3 Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Body Weight; Collagen; Connective Tissue Growth Factor; Creatine; Hypertension; Imidazoles; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Male; Nephrectomy; Organ Size; Peptidyl-Dipeptidase A; Proteinuria; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium Chloride; Tetrazoles; Transforming Growth Factor beta	2006
The antagonism of aldosterone receptor prevents the development of hypertensive heart failure induced by chronic inhibition of nitric oxide synthesis in rats. Cardiovascular drugs and therapy, 2006, Volume: 20, Issue:2 Topics: Actins; Aldosterone; Animals; Blotting, Western; Cytochrome P-450 CYP11B2; Drug Therapy, Combination; Eplerenone; Fibrosis; Heart Failure; Heart Ventricles; Hypertension; Immunohistochemistry; Male; Mineralocorticoid Receptor Antagonists; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Proliferating Cell Nuclear Antigen; Protein Precursors; Random Allocation; Rats; Rats, Inbred WKY; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone; Transforming Growth Factor beta; Transforming Growth Factor beta1	2006
Involvements of Rho-kinase and TGF-beta pathways in aldosterone-induced renal injury. Journal of the American Society of Nephrology : JASN, 2006, Volume: 17, Issue:8 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aldosterone; Animals; Enzyme Activation; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Kidney; Male; Nephrectomy; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Time Factors; Transforming Growth Factor beta	2006
Aldosterone promotes fibronectin production through a Smad2-dependent TGF-beta1 pathway in mesangial cells. Biochemical and biophysical research communications, 2006, Sep-15, Volume: 348, Issue:1 Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Animals; Cells, Cultured; Cytochrome P-450 CYP11B2; Extracellular Matrix; Fibronectins; Male; Mesangial Cells; Rats; Receptors, Mineralocorticoid; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1	2006
Aldosterone blockage in proliferative glomerulonephritis prevents not only fibrosis, but proliferation as well. Renal failure, 2006, Volume: 28, Issue:6 Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Cell Proliferation; Disease Models, Animal; Diuretics; Fibrosis; Glomerulonephritis, Membranoproliferative; Ki-67 Antigen; Kidney; Mineralocorticoid Receptor Antagonists; Rats; Rats, Sprague-Dawley; Spironolactone; Tetrazoles; Transforming Growth Factor beta; Valine; Valsartan	2006
Inhibition of prostasin-induced ENaC activities by PN-1 and regulation of PN-1 expression by TGF-beta1 and aldosterone. Kidney international, 2006, Volume: 70, Issue:8 Topics: Aldosterone; Amyloid beta-Protein Precursor; Animals; Biological Transport; Cell Line; Electrophysiology; Epithelial Sodium Channels; Female; Gene Expression Regulation; Gene Silencing; Kidney Tubules, Collecting; Mice; Oocytes; Protease Nexins; Receptors, Cell Surface; RNA, Messenger; Serine Endopeptidases; Sodium; Sodium Channels; Transforming Growth Factor beta; Transforming Growth Factor beta1; Xenopus	2006
Mineralocorticoid receptor activation promotes vascular cell calcification. Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:4 Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenal Cortex Hormones; Aldosterone; Alkaline Phosphatase; Animals; Aorta; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Calcinosis; Cattle; Cells, Cultured; Coronary Vessels; Humans; Minerals; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptors, Mineralocorticoid; Signal Transduction; Transforming Growth Factor beta; Vascular Diseases	2007
Antagonistic effects of bone morphogenetic protein-4 and -7 on renal mesangial cell proliferation induced by aldosterone through MAPK activation. American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:5 Topics: Aldosterone; Animals; Bone Morphogenetic Protein 4; Bone Morphogenetic Protein 7; Bone Morphogenetic Protein Receptors, Type I; Bone Morphogenetic Proteins; Cell Line; Cell Proliferation; Enzyme Activation; Eplerenone; Extracellular Signal-Regulated MAP Kinases; JNK Mitogen-Activated Protein Kinases; Mesangial Cells; Mice; Mineralocorticoid Receptor Antagonists; Mitogen-Activated Protein Kinases; Mitosis; Phosphorylation; Signal Transduction; Smad6 Protein; Spironolactone; Transforming Growth Factor beta	2007
Dual blockade of aldosterone and angiotensin II additively suppresses TGF-beta and NADPH oxidase in the hypertensive kidney. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:5 Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiac Output, Low; Drug Synergism; Eplerenone; Hypertension; Indoles; Kidney; Male; Mineralocorticoid Receptor Antagonists; NADPH Oxidases; Oxidative Stress; Rats; Rats, Inbred Dahl; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase; Spironolactone; Superoxide Dismutase; Transforming Growth Factor beta	2007
Renal inflammation is modulated by potassium in chronic kidney disease: possible role of Smad7. American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:4 Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Chronic Disease; Creatinine; Disease Models, Animal; Kidney; Kidney Diseases; Male; Nephritis; NF-kappa B; Potassium; Potassium, Dietary; Rats; Rats, Sprague-Dawley; Smad7 Protein; Sodium; Transforming Growth Factor beta	2007
Local renal aldosterone production induces inflammation and matrix formation in kidneys of diabetic rats. Experimental physiology, 2008, Volume: 93, Issue:7 Topics: Adrenalectomy; Albuminuria; Aldosterone; Animals; Blood Glucose; Collagen Type IV; Cytochrome P-450 CYP11B2; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Fibronectins; Inflammation; Interleukin-6; Kidney; NF-kappa B; Rats; RNA, Messenger; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2008
Aldosterone, but not angiotensin II, increases profibrotic factors in kidney of adrenalectomized stroke-prone spontaneously hypertensive rats. American journal of physiology. Endocrinology and metabolism, 2008, Volume: 295, Issue:2 Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Fibrosis; Immunohistochemistry; Kidney; Kidney Diseases; Male; Osteopontin; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred SHR; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Smad2 Protein; Smad7 Protein; Transforming Growth Factor beta	2008
Primary aldosteronism can alter peripheral levels of transforming growth factor beta and tumor necrosis factor alpha. Journal of endocrinological investigation, 2009, Volume: 32, Issue:9 Topics: Adult; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Interleukin-10; Male; Middle Aged; Renin; Renin-Angiotensin System; Spironolactone; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2009
Oxidative stress-related proteins in a Conn's adenoma tissue. Relevance for aldosterone's prooxidative and proinflammatory activity. Journal of endocrinological investigation, 2010, Volume: 33, Issue:1 Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Female; Gene Expression; Heme Oxygenase-1; Humans; Hyperaldosteronism; NADPH Oxidases; Oxidative Stress; Plasminogen Activator Inhibitor 1; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Transforming Growth Factor beta	2010
Inhibitory effects of a dihydropyridine calcium channel blocker on renal injury in aldosterone-infused rats. Journal of hypertension, 2009, Volume: 27, Issue:9 Topics: Aldosterone; Animals; Azetidinecarboxylic Acid; Blood Pressure; Body Weight; Calcium Channel Blockers; Collagen Type IV; Connective Tissue Growth Factor; Creatinine; Dihydropyridines; Ethidium; Gene Expression; Kidney; Kidney Diseases; Male; Mesangial Cells; NADPH Oxidases; Organ Size; Proteinuria; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta	2009
Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism. American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:5 Topics: Administration, Oral; Aldosterone; Animals; Cardiomegaly; Collagen Type I; Cytochrome P-450 CYP1A1; Disease Models, Animal; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Hyperaldosteronism; Hypertension; Indoles; Intercellular Adhesion Molecule-1; Magnetic Resonance Imaging; Membrane Glycoproteins; Mice; Myocardium; NADPH Oxidase 2; NADPH Oxidases; Phosphorylation; Promoter Regions, Genetic; Rats; Rats, Inbred F344; Rats, Transgenic; Renin; RNA, Messenger; Time Factors; Transforming Growth Factor beta	2009
Dietary salt restriction activates mineralocorticoid receptor signaling in volume-overloaded heart failure. European journal of pharmacology, 2009, Nov-25, Volume: 623, Issue:1-3 Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Body Weight; Cell Size; Contraindications; Diet, Sodium-Restricted; Endomyocardial Fibrosis; Heart; Heart Failure; Hemodynamics; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Myocytes, Cardiac; Natriuretic Peptide, Brain; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Signal Transduction; Spironolactone; Transforming Growth Factor beta; Tyrosine; Ventricular Remodeling	2009
Circulating biomarkers of collagen metabolism in cardiac diseases. Circulation, 2010, Apr-13, Volume: 121, Issue:14 Topics: Aldosterone; Biomarkers; Carrier Proteins; Collagen; Connective Tissue Growth Factor; Heart Diseases; Heart Failure; Humans; Matrix Metalloproteinase 1; Myocardium; Myocytes, Cardiac; Peptide Fragments; Procollagen; Stroke Volume; Transforming Growth Factor beta	2010
Salt-induced cardiac hypertrophy and interstitial fibrosis are due to a blood pressure-independent mechanism in Wistar rats. The Journal of nutrition, 2010, Volume: 140, Issue:10 Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Collagen Type I; Collagen Type III; Disease Models, Animal; Drinking; Eating; Echocardiography; Fibrosis; Gene Expression; Heart Ventricles; Hydralazine; Hypertension; Losartan; Male; Myocardium; Potassium; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Sodium; Sodium Chloride, Dietary; Transforming Growth Factor beta; Urine	2010
Amlodipine suppressed cardiac gene expression of brain natriuretic peptide, transforming growth factor-β₁ and fibronectin mediated by aldosterone in male stroke-prone spontaneously hypertensive rats. The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:12 Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiotonic Agents; Fibronectins; Gene Expression Regulation; Heart; Hypertension; Male; Myocardium; Natriuretic Peptide, Brain; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; Transforming Growth Factor beta	2010
Aldosterone/NaCl-induced renal and cardiac fibrosis is modulated by TGF-β responsiveness of T cells. Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:5 Topics: Aldosterone; Animals; Blood Pressure; Collagen; Extracellular Matrix; Fibronectins; Fibrosis; Kidney; Mice; Mice, Transgenic; Myocardium; Organ Size; Plasminogen Activator Inhibitor 1; Proteinuria; Sodium Chloride, Dietary; T-Lymphocytes; Transforming Growth Factor beta	2011
Oxidative damages in tubular epithelial cells in IgA nephropathy: role of crosstalk between angiotensin II and aldosterone. Journal of translational medicine, 2011, Oct-06, Volume: 9 Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Angiotensin II; Apoptosis; Cells, Cultured; Cytochrome P-450 CYP11B2; Epithelial Cells; Female; Gene Expression Regulation; Glomerulonephritis, IGA; Humans; Immunoglobulin A; Kidney Tubules, Proximal; Male; Mesangial Cells; Oxidative Stress; Receptor, Angiotensin, Type 2; Receptors, Mineralocorticoid; Renin-Angiotensin System; Time Factors; Transforming Growth Factor beta; Up-Regulation	2011
AMP-activated protein kinase inhibits TGF-β-, angiotensin II-, aldosterone-, high glucose-, and albumin-induced epithelial-mesenchymal transition. American journal of physiology. Renal physiology, 2013, Mar-15, Volume: 304, Issue:6 Topics: Albumins; Aldosterone; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Angiotensin II; Cell Line; Epithelial-Mesenchymal Transition; Glucose; Heme Oxygenase-1; Humans; Metformin; NADPH Oxidase 4; NADPH Oxidases; Nephrosclerosis; Pyrazoles; Pyrimidines; Reactive Oxygen Species; Ribonucleosides; Thioredoxins; Transforming Growth Factor beta	2013
Renal sympathetic denervation suppresses ventricular substrate remodelling in a canine high-rate pacing model. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2014, Volume: 10, Issue:3 Topics: Aldosterone; Angiotensin II; Animals; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Catheter Ablation; Disease Models, Animal; Disease Progression; Dogs; Female; Fibrosis; Heart Failure; Heart Ventricles; Kidney; Male; Natriuretic Peptide, Brain; Sympathectomy; Time Factors; Transforming Growth Factor beta; Ventricular Function, Left; Ventricular Pressure; Ventricular Remodeling	2014
Aldosterone induces fibrosis, oxidative stress and DNA damage in livers of male rats independent of blood pressure changes. Toxicology and applied pharmacology, 2014, Nov-01, Volume: 280, Issue:3 Topics: Aldosterone; Animals; Blood Pressure; Blotting, Western; Cyclic N-Oxides; Histocytochemistry; Liver Cirrhosis; Male; Mineralocorticoid Receptor Antagonists; NF-E2-Related Factor 2; Oxidative Stress; Random Allocation; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA; Spin Labels; Spironolactone; Statistics, Nonparametric; Transforming Growth Factor beta	2014
DACH1, a zona glomerulosa selective gene in the human adrenal, activates transforming growth factor-β signaling and suppresses aldosterone secretion. Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:5 Topics: Adrenocortical Carcinoma; Aldosterone; Disease Progression; Eye Proteins; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Middle Aged; Real-Time Polymerase Chain Reaction; RNA, Neoplasm; Signal Transduction; Transcription Factors; Transforming Growth Factor beta; Tumor Cells, Cultured; Zona Glomerulosa	2015
Mesenchymal Stromal Cells Prevent Renal Fibrosis in a Rat Model of Unilateral Ureteral Obstruction by Suppressing the Renin-Angiotensin System via HuR. PloS one, 2016, Volume: 11, Issue:2 Topics: Aldosterone; Angiotensin II; Animals; Animals, Genetically Modified; Apoptosis; Cell Differentiation; Cell Line; Disease Models, Animal; ELAV-Like Protein 1; Fibrosis; Green Fluorescent Proteins; Humans; Immunophenotyping; Interleukin-10; Kidney; Kidney Tubules; Male; Mesenchymal Stem Cells; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Transforming Growth Factor beta; Ureteral Obstruction	2016
Aldosterone antagonist therapy and its relationship with inflammation, fibrosis, thrombosis, mineral-bone disorder and cardiovascular complications in peritoneal dialysis (PD) patients. International urology and nephrology, 2017, Volume: 49, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Biomarkers; Blood Pressure; Cardiovascular Diseases; Chronic Kidney Disease-Mineral and Bone Disorder; Echocardiography; Female; Fibrosis; Humans; Inflammation; Interleukin-6; Male; Matrix Metalloproteinase 2; Middle Aged; Mineralocorticoid Receptor Antagonists; Osteopontin; P-Selectin; Parathyroid Hormone; Peritoneal Dialysis; Pulse Wave Analysis; Renal Insufficiency, Chronic; Spironolactone; Thrombosis; Transforming Growth Factor beta; Vascular Stiffness	2017
Mineralocorticoid receptor antagonism protects the aorta from vascular smooth muscle cell proliferation and collagen deposition in a rat model of adrenal aldosterone-producing adenoma. Journal of physiology and biochemistry, 2018, Volume: 74, Issue:1 Topics: ACTH-Secreting Pituitary Adenoma; Aldosterone; Animals; Antihypertensive Agents; Aorta; Cell Proliferation; Collagen; Disease Models, Animal; Eplerenone; Hydralazine; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Proto-Oncogene Proteins c-mdm2; Random Allocation; Rats, Sprague-Dawley; Spironolactone; Transforming Growth Factor beta; Vascular Remodeling; Vasodilator Agents	2018
The Impact of Spironolactone on Markers of Myocardial Oxidative Status, Inflammation and Remodeling in Hyperthyroid Rats. Current molecular pharmacology, 2020, Volume: 13, Issue:3 Topics: Aldosterone; Animals; Antioxidants; Biomarkers; Blood Pressure; Body Weight; Cardiovascular Diseases; Endothelin-1; Heart; Heart Rate; Hyperthyroidism; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Nitrites; Organ Size; Oxidative Stress; Random Allocation; Rats; Spironolactone; Thyroid Hormones; Thyroxine; Transforming Growth Factor beta	2020
Altered Tregs Differentiation and Impaired Autophagy Correlate to Atherosclerotic Disease. Frontiers in immunology, 2020, Volume: 11 Topics: Aldosterone; Animals; Apolipoproteins E; Atherosclerosis; Autophagy; Cell Differentiation; Cell Polarity; Disease Models, Animal; Forkhead Transcription Factors; Humans; Male; Mice; Mice, Inbred C57BL; Plaque, Atherosclerotic; T-Lymphocytes, Regulatory; Transforming Growth Factor beta	2020