Page last updated: 2024-08-17

aldosterone and dihydropyridines

aldosterone has been researched along with dihydropyridines in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.27)18.7374
1990's12 (27.27)18.2507
2000's11 (25.00)29.6817
2010's19 (43.18)24.3611
2020's1 (2.27)2.80

Authors

AuthorsStudies
Barrett, PQ; Isales, CM; Lewicki, JA; Nee, JJ1
Bilodeau, L; Durroux, T; Gallo-Payet, N; Payet, MD1
Asayama, J; Itoh, H; Kuwabara, T; Nakagawa, M; Nakata, T; Sasaki, S; Takeda, K; Takesako, T; Tanabe, S; Yamahara, Y1
Bursztyn, M; Grossman, E; Rosenthal, T1
Barrett, PQ; Cohen, CJ; Ertel, EA; Nee, JJ; Smith, MM1
Kasuya, Y; Masuda, Y; Sakai, T; Shigenobu, K; Shudo, C; Tanaka, S1
Bocciolone, M; Boselli, L; Comerio, G; Cuspidi, C; Leonetti, G; Lonati, L; Sampieri, L; Zanchetti, A1
Elliott, HL1
Saruta, T; Suzuki, H1
Iimura, O; Shimamoto, K1
Chin Kon Sung, UG; Corbeij, HM; de Vries, RJ; Dunselman, PH; Lie, KI; van Gilst, WH; van Veldhuisen, DJ1
Brochu, M; Jodoin, S; Picard, S; St-Louis, J1
Beuck, M; Dressel, J; Fey, P; Frobel, K; Hirth-Dietrich, C; Hübsch, W; Kazda, S; Knorr, A; Krämer, T; Sander, E; Stasch, JP1
Horii, M; Imagawa, K; Kawata, H; Nakajima, T; Naya, N; Okayama, S; Saito, Y; Takaoka, M; Uemura, S1
Horii, M; Imagawa, K; Iwama, H; Kawata, H; Nakajima, T; Naya, N; Okayama, S; Saito, Y; Somekawa, S; Uemura, S1
Akashiba, A; Ishimitsu, T; Kameda, T; Matsuoka, H; Minami, J; Numabe, A; Ohta, S; Ono, H; Takahashi, T; Yoshii, M1
Fujii, M; Horie, M; Sakai, H; Tanaka, T; Tsutamoto, T; Yamamoto, T1
Blinn, JR; Bolten, CW; Dietz, JD; Du, S; Funder, JW; Hu, X; Payne, MA; Xia, C1
Akizuki, O; Inayoshi, A; Kitayama, T; Kusaka, H; Matsubara, M; Sasaki, K; Shirakura, S; Yao, K1
Ikeda, K; Inada, Y; Isaka, T; Tajima, N; Takada, Y; Tojo, K1
Aritomi, S; Enomoto, A; Koganei, H; Konda, T; Niinuma, K; Nitta, K; Ogawa, T1
Fujii, M; Horie, M; Kawahara, C; Nishiyama, K; Tanaka, T; Tsutamoto, T; Yamaji, M; Yamamoto, T1
Du, J; Fan, YY; Fu, H; Fujisawa, Y; Hitomi, H; Hosomi, N; Kimura, S; Kiyomoto, H; Kohno, M; Lu, XM; Nagai, Y; Nakano, D; Nishiyama, A; Ohmori, K1
Ban, N; Endo, K; Kawana, H; Miyashita, Y; Nagayama, D; Ohhira, M; Oyama, T; Saiki, A; Sasaki, H; Shirai, K; Yamaguchi, T1
Bärfacker, L; Heidland, A; Kolkhof, P; Queisser, N; Schäfer, S; Schupp, N; Stopper, H; Wolf, M1
Adachi, M; Aritomi, S; Hayata, M; Kakizoe, Y; Kitamura, K; Ko, T; Konda, T; Miyoshi, T; Shiraishi, N; Tomita, K; Uchimura, K; Wakida, N1
Hirayama, K; Kitayama, T; Kosaka, H; Kusaka, H; Matsubara, M; Sasaki, K; Yoda, N1
Araki, E; Goto, R; Kondo, T; Miyamura, N; Ono, K; Sonoda, K; Takaki, Y; Yasuda, T; Yatsuda, R1
Glendenning, P; Grasko, JM; Nguyen, HH1
Inada, H; Ishimitsu, T; Matsuoka, H; Nakano, N; Ohba, S; Okamura, A; Takahashi, T1
Arakawa, K; Fujii, M; Inoki, I; Kimura, T; Konoshita, T; Makino, Y; Miyamori, I; Nakamura, H; Wakahara, S1
Abe, M; Fujita, T; Maruyama, N; Maruyama, T; Matsumoto, K; Matsumoto, S; Okada, K; Soma, M1
Eguchi, K; Ishikawa, J; Kario, K; Matsui, Y; O'Rourke, MF; Shimada, K1
Abe, M; Maruyama, N; Matsumoto, K; Matsumoto, S; Okada, K; Soma, M1
Aritomi, S; Konda, T; Yoshimura, M1
Furusho, H; Kaneko, S; Kitano, K; Ohtani, K; Okajima, M; Takamura, M; Takashima, S; Usui, S; Yamamoto, K1
Kim-Mitsuyama, S1
Abe, M; Inoshita, A; Maruyama, N; Okada, K; Soma, M; Suzuki, H; Yoshida, Y1
Alexandre, J; Beygui, F; Guinamard, R; Hof, T; Manrique, A; Milliez, P; Puddu, PE; Rouet, R; Sallé, L; Simard, C1
Hirayama, A; Nagao, K; Takahashi, A; Tani, S1
Ichihara, A; Itoh, H; Nishimura, T; Sekioka, R; Tanaka, M1
Deinum, J; Lenders, JW; Riksen, NP1
Fujii, M; Ichikawa, M; Imagawa, M; Ishizuka, T; Kaeriyama, S; Konoshita, T; Makino, Y; Nakamura, H; Nakaya, T; Sato, S; Suzuki, J; Urabe, M; Wakahara, S; Yamada, M; Yamamoto, K; Zenimaru, Y1
Acosta-García, LM; Alvarez de la Rosa, D; Aranda, MT; González-Muñiz, R; Martín-Martínez, M; Passeri, D; Pellicciari, R; Pérez de Vega, MJ; Pérez-Gordillo, FL; Serrano-Morillas, N1

Reviews

3 review(s) available for aldosterone and dihydropyridines

ArticleYear
Calcium antagonism: aldosterone and vascular responses to catecholamines and angiotensin II in man.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:6

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Cardiovascular Physiological Phenomena; Cardiovascular System; Dihydropyridines; Humans; Hypertension; Norepinephrine; Vascular Resistance; Vasoconstriction

1993
[Bone and calcium update; research of calcium metabolism on cardiovascular system update. Calcium channel blocker update].
    Clinical calcium, 2011, Volume: 21, Issue:12

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Calcium Channels; Cardiovascular Diseases; Clinical Trials as Topic; Dihydropyridines; Drug Therapy, Combination; Humans; Hypertension; Kidney Diseases; Meta-Analysis as Topic; Sympathetic Nervous System

2011
Pharmacological treatment of aldosterone excess.
    Pharmacology & therapeutics, 2015, Volume: 154

    Topics: Aldosterone; Cytochrome P-450 CYP11B2; Dihydropyridines; Drug Interactions; Epithelial Sodium Channel Blockers; Eplerenone; Glucocorticoids; Heart Failure; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Spironolactone

2015

Trials

15 trial(s) available for aldosterone and dihydropyridines

ArticleYear
Antihypertensive and humoral effects of verapamil and lacidipine in combination in hypertensive patients.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:5

    Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Renin; Verapamil

1993
Efficacy of manidipine in the treatment of hypertension with renal impairment: a multicenter trial.
    American heart journal, 1993, Volume: 125, Issue:2 Pt 2

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Blood Urea Nitrogen; Calcium Channel Blockers; Creatinine; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Nitrobenzenes; Piperazines; Renin; Treatment Outcome

1993
Effects of lacidipine on peak oxygen consumption, neurohormones and invasive haemodynamics in patients with mild to moderate chronic heart failure.
    Heart (British Cardiac Society), 1996, Volume: 75, Issue:2

    Topics: Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Digoxin; Dihydropyridines; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Norepinephrine; Oxygen Consumption; Prospective Studies; Renin; Stroke Volume; Vascular Resistance

1996
Blocking T-type Ca2+ channels with efonidipine decreased plasma aldosterone concentration in healthy volunteers.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:7

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Calcium Channel Blockers; Calcium Channels, T-Type; Cross-Over Studies; Depression, Chemical; Dihydropyridines; Hemodynamics; Humans; Male; Neurotransmitter Agents; Nifedipine; Nitrophenols; Organophosphorus Compounds; Renin; Water-Electrolyte Balance

2006
Efonidipine reduces proteinuria and plasma aldosterone in patients with chronic glomerulonephritis.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:7

    Topics: Adult; Aged; Aldosterone; Amlodipine; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Chronic Disease; Cross-Over Studies; Dihydropyridines; Female; Glomerulonephritis; Humans; Male; Middle Aged; Nitrophenols; Organophosphorus Compounds; Proteinuria

2007
Comparison of the effects of efonidipine and amlodipine on aldosterone in patients with hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:8

    Topics: Aged; Aged, 80 and over; Aldosterone; Amlodipine; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Natriuretic Peptide, Brain; Nitrophenols; Norepinephrine; Organophosphorus Compounds

2007
Long-term effect of efonidipine therapy on plasma aldosterone and left ventricular mass index in patients with essential hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:8

    Topics: Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Natriuretic Peptide, Brain; Nitrophenols; Organophosphorus Compounds; Renin; Time Factors

2009
Protective effects of efonidipine, a T- and L-type calcium channel blocker, on renal function and arterial stiffness in type 2 diabetic patients with hypertension and nephropathy.
    Journal of atherosclerosis and thrombosis, 2009, Volume: 16, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Aldosterone; Amlodipine; Arteries; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Deoxyguanosine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dihydropyridines; Female; Glycated Hemoglobin; Humans; Hypertension; Kidney; Lipids; Male; Middle Aged; Nitrophenols; Organophosphorus Compounds

2009
Effects of efonidipine, an L- and T-type calcium channel blocker, on the renin-angiotensin-aldosterone system in chronic hemodialysis patients.
    International heart journal, 2010, Volume: 51, Issue:3

    Topics: Aged; Aldosterone; Amlodipine; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cross-Over Studies; Dihydropyridines; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitrophenols; Organophosphorus Compounds; Renal Dialysis; Renin-Angiotensin System

2010
A new-generation N/L-type calcium channel blocker leads to less activation of the renin-angiotensin system compared with conventional L type calcium channel blocker.
    Journal of hypertension, 2010, Volume: 28, Issue:10

    Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin I; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System

2010
Benidipine reduces albuminuria and plasma aldosterone in mild-to-moderate stage chronic kidney disease with albuminuria.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:2

    Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Chronic Disease; Diabetic Nephropathies; Dihydropyridines; Female; Glomerular Filtration Rate; Glomerulonephritis; Humans; Hypertension; Male; Middle Aged; Nephrosclerosis; Potassium; Severity of Illness Index; Sodium

2011
Association between aldosterone induced by antihypertensive medication and arterial stiffness reduction: the J-CORE study.
    Atherosclerosis, 2011, Volume: 215, Issue:1

    Topics: Aged; Aldosterone; Antihypertensive Agents; Aorta; Azetidinecarboxylic Acid; Blood Flow Velocity; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Imidazoles; Male; Pulsatile Flow; Tetrazoles; Vascular Resistance

2011
Additive antioxidative effects of azelnidipine on angiotensin receptor blocker olmesartan treatment for type 2 diabetic patients with albuminuria.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:8

    Topics: Aged; Albuminuria; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles

2011
L/N-type calcium channel blocker cilnidipine reduces plasma aldosterone, albuminuria, and urinary liver-type fatty acid binding protein in patients with chronic kidney disease.
    Heart and vessels, 2013, Volume: 28, Issue:4

    Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Creatinine; Dihydropyridines; Down-Regulation; Fatty Acid-Binding Proteins; Female; Humans; Hypertension; Japan; Linear Models; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Renal Insufficiency, Chronic; Time Factors; Treatment Outcome

2013
Effects of the T/L-type calcium channel blocker benidipine on albuminuria and plasma aldosterone concentration. A pilot study involving switching from L-type calcium channel blockers to benidipine.
    International heart journal, 2014, Volume: 55, Issue:6

    Topics: Aged; Albuminuria; Aldosterone; Blood Pressure; Calcium Channel Blockers; Creatinine; Dihydropyridines; Female; Glomerular Filtration Rate; Humans; Hypertension; Male; Middle Aged; Pilot Projects; Prospective Studies; Renin

2014

Other Studies

26 other study(ies) available for aldosterone and dihydropyridines

ArticleYear
ANP-(7-23) stimulates a DHP-sensitive Ca2+ conductance and reduces cellular cAMP via a cGMP-independent mechanism.
    The American journal of physiology, 1992, Volume: 263, Issue:2 Pt 1

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Calcium; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dihydropyridines; Electric Conductivity; Intracellular Membranes; Peptide Fragments; Zona Glomerulosa

1992
Background calcium permeable channels in glomerulosa cells from adrenal gland.
    The Journal of membrane biology, 1992, Volume: 129, Issue:2

    Topics: Aldosterone; Animals; Biological Transport; Calcium; Calcium Channels; Cattle; Cell Membrane Permeability; Cells, Cultured; Dihydropyridines; Electric Conductivity; Membrane Potentials; Nifedipine; Rats; Zona Glomerulosa

1992
Effect of manidipine on cardiac hypertrophy and coronary circulation in DOCA/salt hypertensive rats.
    Blood pressure. Supplement, 1992, Volume: 3

    Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Coronary Circulation; Coronary Vessels; Desoxycorticosterone; Dihydropyridines; Electrolytes; Heart Rate; Hypertension; Male; Nitrobenzenes; Piperazines; Rats; Rats, Wistar; Renin; Sodium Chloride

1992
The absence of long-term therapeutic effect of calcium channel blockade in the primary aldosteronism of adrenal adenomas.
    American journal of hypertension, 1988, Volume: 1, Issue:3 Pt 3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Calcium Channel Blockers; Dihydropyridines; Humans; Hyperaldosteronism; Male; Potassium; Renin

1988
Voltage-gated calcium currents have two opposing effects on the secretion of aldosterone.
    The American journal of physiology, 1995, Volume: 268, Issue:4 Pt 1

    Topics: Agatoxins; Aldosterone; Animals; Calcium Channel Blockers; Calcium Channels; Cattle; Dihydropyridines; Electric Conductivity; Electrophysiology; Nickel; Potassium; Spider Venoms; Zona Glomerulosa

1995
Effects of long-term oral administration of NZ-105, a novel calcium antagonist, with or without propranolol in spontaneously hypertensive rats.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:6

    Topics: Administration, Oral; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Heart; Heart Rate; Hypertension; Kidney; Liver; Male; Nitrophenols; Organ Size; Organophosphorus Compounds; Propranolol; Rats; Rats, Inbred SHR; Renin; Time Factors

1993
Efficacy and mode of action of manidipine: a new calcium antagonist.
    American heart journal, 1993, Volume: 125, Issue:2 Pt 2

    Topics: Adult; Aldosterone; Calcium; Calcium Channel Blockers; Dihydropyridines; Diuresis; Female; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Natriuresis; Nitrobenzenes; Norepinephrine; Piperazines; Renin; Treatment Outcome

1993
Effects of dihydropyridines on aldosterone secretion in adrenal capsule preparations from pregnant rats.
    The American journal of physiology, 1997, Volume: 272, Issue:1 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Calcium; Dihydropyridines; Dose-Response Relationship, Drug; Female; Osmolar Concentration; Potassium; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley

1997
Long-term blockade of the angiotensin II receptor in renin transgenic rats, salt-loaded Dahl rats, and stroke-prone spontaneously hypertensive rats.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:9

    Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Atrial Natriuretic Factor; Body Weight; Cerebrovascular Disorders; Cyclic GMP; Dihydropyridines; Hemodynamics; Hormones; Hypertension; Kidney; Rats; Rats, Inbred SHR; Renin; Tetrazoles

1997
Inhibitory effect of efonidipine on aldosterone synthesis and secretion in human adrenocarcinoma (H295R) cells.
    Journal of cardiovascular pharmacology, 2006, Volume: 47, Issue:1

    Topics: Adrenal Gland Neoplasms; Aldosterone; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Line, Tumor; Cytochrome P-450 CYP11B2; Dihydropyridines; Humans; Nitrophenols; Organophosphorus Compounds; RNA, Messenger

2006
A number of marketed dihydropyridine calcium channel blockers have mineralocorticoid receptor antagonist activity.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:3

    Topics: Adrenalectomy; Aldosterone; Animals; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Epithelial Sodium Channels; Male; Mineralocorticoid Receptor Antagonists; Models, Molecular; Mutation; Nimodipine; Protein Binding; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid

2008
Blockade of T-type voltage-dependent Ca2+ channels by benidipine, a dihydropyridine calcium channel blocker, inhibits aldosterone production in human adrenocortical cell line NCI-H295R.
    European journal of pharmacology, 2008, Apr-28, Volume: 584, Issue:2-3

    Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Line; Cytochrome P-450 CYP11B2; Dihydropyridines; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Humans; Membrane Potentials; Patch-Clamp Techniques; Potassium Chloride; RNA, Messenger; Steroid 11-beta-Hydroxylase; Tetrazoles; Valine; Valsartan

2008
Azelnidipine inhibits aldosterone synthesis and secretion in human adrenocortical cell line NCI-H295R.
    European journal of pharmacology, 2009, Mar-01, Volume: 605, Issue:1-3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Angiotensin II; Azetidinecarboxylic Acid; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Line, Tumor; Cytochrome P-450 CYP11B2; Dihydropyridines; Gene Expression Regulation; Humans; Nitrophenols; Organophosphorus Compounds; Potassium Chloride; Steroid 11-beta-Hydroxylase

2009
Different effects of L/N-type and L-type calcium channel blockers on the renin-angiotensin-aldosterone system in SHR/Izm.
    American journal of nephrology, 2009, Volume: 30, Issue:2

    Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Conotoxins; Dihydropyridines; Humans; Male; Norepinephrine; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; Time Factors

2009
Inhibitory effects of a dihydropyridine calcium channel blocker on renal injury in aldosterone-infused rats.
    Journal of hypertension, 2009, Volume: 27, Issue:9

    Topics: Aldosterone; Animals; Azetidinecarboxylic Acid; Blood Pressure; Body Weight; Calcium Channel Blockers; Collagen Type IV; Connective Tissue Growth Factor; Creatinine; Dihydropyridines; Ethidium; Gene Expression; Kidney; Kidney Diseases; Male; Mesangial Cells; NADPH Oxidases; Organ Size; Proteinuria; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta

2009
Aldosterone causes DNA strand breaks and chromosomal damage in renal cells, which are prevented by mineralocorticoid receptor antagonists.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2010, Volume: 42, Issue:6

    Topics: Aldosterone; Animals; Cells, Cultured; Chromones; Chromosomes; Comet Assay; Cytoprotection; Dihydropyridines; DNA Breaks; DNA Damage; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hormone Antagonists; Kidney; Micronucleus Tests; Mifepristone; Mineralocorticoid Receptor Antagonists; Spironolactone; Swine

2010
Regulation of adrenal aldosterone production by serine protease prostasin.
    Journal of biomedicine & biotechnology, 2010, Volume: 2010

    Topics: Adrenal Cortex; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Calcium Channel Blockers; Cell Line; Cytochrome P-450 CYP11B2; Dihydropyridines; Gene Expression Regulation; Gene Silencing; Humans; Nitrophenols; Organophosphorus Compounds; Promoter Regions, Genetic; Rats; Receptors, Proteinase-Activated; Recombinant Proteins; Serine Endopeptidases; Tetrazoles; Transfection; Valine; Valsartan

2010
The L-, N-, and T-type triple calcium channel blocker benidipine acts as an antagonist of mineralocorticoid receptor, a member of nuclear receptor family.
    European journal of pharmacology, 2010, Jun-10, Volume: 635, Issue:1-3

    Topics: Aldosterone; Binding Sites; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Calcium Channels, T-Type; Cell Line; Dihydropyridines; Eplerenone; Humans; Mineralocorticoid Receptor Antagonists; Models, Molecular; Molecular Conformation; Mutation; Pyridines; Receptors, Mineralocorticoid; Spironolactone; Stereoisomerism

2010
Plasma renin activity and aldosterone concentration are not altered by the novel calcium channel antagonist, azelnidipine, in hypertensive patients.
    Internal medicine (Tokyo, Japan), 2010, Volume: 49, Issue:7

    Topics: Aged; Aged, 80 and over; Aldosterone; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Renin

2010
Delayed diagnosis of primary hyperaldosteronism.
    BMJ (Clinical research ed.), 2010, May-25, Volume: 340

    Topics: Adult; Aldosterone; Calcium Channel Blockers; Delayed Diagnosis; Dihydropyridines; Drug Resistance; Female; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Male; Middle Aged; Potassium; Renin

2010
L/N-type calcium channel blocker suppresses reflex aldosterone production induced by antihypertensive action.
    Heart and vessels, 2012, Volume: 27, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Disease Models, Animal; Down-Regulation; Hypertension; Injections, Intravenous; Male; Nifedipine; Rats; Rats, Inbred SHR; Reflex; Renin-Angiotensin System

2012
Benidipine reduces ischemia reperfusion-induced systemic oxidative stress through suppression of aldosterone production in mice.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:3

    Topics: Aldosterone; Animals; Apoptosis; Calcium Channel Blockers; Dihydropyridines; Disease Models, Animal; Down-Regulation; Hemodynamics; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; Oxidative Stress; Ventricular Dysfunction, Left

2012
Proarrhythmic effects of aldosterone during myocardial ischemia-reperfusion: implication of the sarcolemmal-KATP channels.
    Journal of cardiovascular pharmacology, 2014, Volume: 64, Issue:2

    Topics: Action Potentials; Aldosterone; Animals; Benzopyrans; Dihydropyridines; Disease Models, Animal; Female; Glyburide; Heart Ventricles; In Vitro Techniques; KATP Channels; Male; Myocardial Reperfusion Injury; Perfusion; Rabbits; Sarcolemma

2014
Effects of cilnidipine on sympathetic nerve activity and cardiorenal function in hypertensive patients with type 2 diabetes mellitus: association with BNP and aldosterone levels.
    Diabetes research and clinical practice, 2014, Volume: 106, Issue:3

    Topics: Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Natriuretic Peptide, Brain; Prognosis; Renin-Angiotensin System; Sympathetic Nervous System

2014
On the top of ARB N/L type Ca channel blocker leads to less elevation of aldosterone.
    Bioscience reports, 2016, Volume: 36, Issue:5

    Topics: Aged; Aldosterone; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Renin-Angiotensin System; Valsartan

2016
Novel 1,4-Dihydropyridine Derivatives as Mineralocorticoid Receptor Antagonists.
    International journal of molecular sciences, 2023, Jan-26, Volume: 24, Issue:3

    Topics: Aldosterone; Calcium Channel Blockers; Dihydropyridines; Mineralocorticoid Receptor Antagonists; Receptors, Mineralocorticoid

2023