Page last updated: 2024-09-03

alanylglutamine and fluorouracil

alanylglutamine has been researched along with fluorouracil in 8 studies

Compound Research Comparison

Studies
(alanylglutamine)
Trials
(alanylglutamine)
Recent Studies (post-2010)
(alanylglutamine)
Studies
(fluorouracil)
Trials
(fluorouracil)
Recent Studies (post-2010) (fluorouracil)
2717311245,5629,30714,663

Protein Interaction Comparison

ProteinTaxonomyalanylglutamine (IC50)fluorouracil (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.32
Thymidylate synthaseMus musculus (house mouse)1.58
AromataseHomo sapiens (human)0.63

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's5 (62.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bai, M; Jiang, Z; Liu, Y1
Bai, M; Jiang, Z; Li, D; Yang, N; Yu, J1
Brito, GA; Carneiro-Filho, BA; Fujii, J; Guerrant, RL; Lima, AA; Obrig, T; Oriá, RB; Wood Rea, K1
Bonomi, M; Cabalar, ME; Castro, MA; Cerchietti, LC; Kirchuk, R; Lutteral, MA; Navigante, AH; Negretti, G; Roth, B; Sheinker, B; Uchima, P1
Gong, QF; Peng, YL; Wand, ZQ1
Bellaguarda, EA; Brito, GA; Leitão, RF; Lira, AM; Macedo, FD; Ribeiro, RA; Silva, LR; Sousa, RB1
Braga-Neto, MB; Brito, GA; Guerrant, RL; Lima, AA; Maciel, AA; Monteiro, MS; Oriá, RB; Warren, CA1
Alves, LA; Aquino, CC; Araújo, CV; Bertolini, LR; Brito, GA; Costa, TB; Figueiredo, IL; Lazzarotto, CR; Lima, AA; Oriá, RB; Ribeiro, RA1

Trials

2 trial(s) available for alanylglutamine and fluorouracil

ArticleYear
Double-blinded, placebo-controlled trial on intravenous L-alanyl-L-glutamine in the incidence of oral mucositis following chemoradiotherapy in patients with head-and-neck cancer.
    International journal of radiation oncology, biology, physics, 2006, Aug-01, Volume: 65, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dipeptides; Double-Blind Method; Fluorouracil; Head and Neck Neoplasms; Humans; Injections, Intravenous; Middle Aged; Mouth Mucosa; Stomatitis

2006
[The prospective study on application of parenteral nutrition with alanyl-glutamine dipeptide in chemotherapy of gastrointestinal neoplasms patients].
    Ai zheng = Aizheng = Chinese journal of cancer, 2006, Volume: 25, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Complement C3; Complement C4; Dipeptides; Double-Blind Method; Female; Fluorouracil; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Leucovorin; Male; Middle Aged; Nitrogen; Parenteral Nutrition; Prealbumin; Prospective Studies; Rectal Neoplasms; Serum Albumin; Stomach Neoplasms; Young Adult

2006

Other Studies

6 other study(ies) available for alanylglutamine and fluorouracil

ArticleYear
[Glutamine dipeptide attenuate mucosal atrophic changes and preservation of gut barrier function following 5-FU intervention].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1996, Volume: 34, Issue:6

    Topics: Animals; Atrophy; Bacterial Translocation; Dipeptides; Fluorouracil; Intestinal Mucosa; Male; Parenteral Nutrition; Permeability; Random Allocation; Rats; Rats, Wistar

1996
[Alanyl-glutamine dipeptides protected the liver function by increasing the hepatic glutathione].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1998, Volume: 20, Issue:2

    Topics: Animals; Dipeptides; Enteritis; Fluorouracil; Glutathione; Liver; Liver Function Tests; Male; Parenteral Nutrition; Random Allocation; Rats; Rats, Wistar

1998
Alanyl-glutamine hastens morphologic recovery from 5-fluorouracil-induced mucositis in mice.
    Nutrition (Burbank, Los Angeles County, Calif.), 2004, Volume: 20, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Body Weight; Cell Division; Dipeptides; Dose-Response Relationship, Drug; Fluorouracil; Intestinal Mucosa; Male; Mice; Mice, Inbred BALB C

2004
Glutamine and alanyl-glutamine accelerate the recovery from 5-fluorouracil-induced experimental oral mucositis in hamster.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Cricetinae; Dipeptides; Fluorouracil; Glutamine; Glutathione; Male; Mesocricetus; Mouth Mucosa; Neutrophil Infiltration; Peroxidase; Stomatitis; Sulfhydryl Compounds

2008
Alanyl-glutamine and glutamine supplementation improves 5-fluorouracil-induced intestinal epithelium damage in vitro.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line; Cell Movement; Cell Proliferation; Dipeptides; Dose-Response Relationship, Drug; Fluorouracil; Glutamine; Intestinal Mucosa; Jejunum; Models, Animal; Rats; Time Factors

2008
Alanyl-glutamine attenuates 5-fluorouracil-induced intestinal mucositis in apolipoprotein E-deficient mice.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2015, Volume: 48, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Apolipoproteins E; Apoptosis; Body Weight; Dipeptides; Female; Fluorouracil; Insulin-Like Growth Factor I; Intestinal Mucosa; Leukocyte Count; Lymphoma, B-Cell; Male; Mice, Inbred C57BL; Mitosis; Mucositis; Random Allocation; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Time Factors; Treatment Outcome

2015