alanyl-glutamyl-aspartic-acid has been researched along with alanyl-glutamyl-aspartyl-glycine* in 1 studies
1 other study(ies) available for alanyl-glutamyl-aspartic-acid and alanyl-glutamyl-aspartyl-glycine
| Article | Year |
|---|---|
Peptide Regulation of Skin Fibroblast Functions during Their Aging In Vitro.
The effect peptides KE, KED, AED and AEDG on proliferation (Ki-67), regeneration and aging (CD98hc), apoptosis (caspase-3), and extracellular matrix remodeling (MMP-9) in skin fibroblasts during their aging in culture were studied by immunofluorescent confocal microscopy. All studied peptides inhibited MMP-9 synthesis that increases during aging of skin fibroblasts and enhanced the expression of Ki-67 and CD98hc that are less intensively synthesized during cell aging. Peptides AED and AEDG suppressed caspase-dependent apoptosis that increases during aging of cell cultures. Topics: Animals; Apoptosis; Caspase 3; Cell Proliferation; Cells, Cultured; Cellular Senescence; Dipeptides; Fibroblasts; Matrix Metalloproteinase 9; Oligopeptides; Rats, Wistar | 2016 |