alanyl-alanyl-phenylalanine chloromethyl ketone and benzyloxycarbonylleucyl-leucyl-leucine aldehyde

alanyl-alanyl-phenylalanine chloromethyl ketone has been researched along with benzyloxycarbonylleucyl-leucyl-leucine aldehyde in 2 studies

Compound Research Comparison

Studies (alanyl-alanyl-phenylalanine chloromethyl ketone)	Trials (alanyl-alanyl-phenylalanine chloromethyl ketone)	Recent Studies (post-2010) (alanyl-alanyl-phenylalanine chloromethyl ketone)	Studies (benzyloxycarbonylleucyl-leucyl-leucine aldehyde)	Trials (benzyloxycarbonylleucyl-leucyl-leucine aldehyde)	Recent Studies (post-2010) (benzyloxycarbonylleucyl-leucyl-leucine aldehyde)
17	0	2	2,473	3	1,057

Protein Interaction Comparison

Protein	Taxonomy	benzyloxycarbonylleucyl-leucyl-leucine aldehyde (IC50)
Proteasome subunit beta type-11	Homo sapiens (human)	1.9893
Calpain-9	Homo sapiens (human)	9.88
Proteasome subunit alpha type-7	Homo sapiens (human)	1.9893
Replicase polyprotein 1ab	Severe acute respiratory syndrome-related coronavirus	3.9
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	3.8999
Aromatase	Homo sapiens (human)	0.044
Indoleamine 2,3-dioxygenase 1	Homo sapiens (human)	0.5
Proteasome subunit beta type-1	Homo sapiens (human)	1.0853
Proteasome subunit alpha type-1	Homo sapiens (human)	1.9893
Proteasome subunit alpha type-2	Homo sapiens (human)	1.9893
Proteasome subunit alpha type-3	Homo sapiens (human)	1.9893
Proteasome subunit alpha type-4	Homo sapiens (human)	1.9893
Proteasome subunit beta type-8	Homo sapiens (human)	1.9893
Proteasome subunit beta type-9	Homo sapiens (human)	1.9893
Proteasome subunit alpha type-5	Homo sapiens (human)	1.9893
Proteasome subunit beta type-4	Homo sapiens (human)	1.9893
Proteasome subunit beta type-6	Homo sapiens (human)	1.9893
Proteasome subunit beta type-5	Homo sapiens (human)	0.6088
Proteasome subunit beta type-10	Homo sapiens (human)	1.9893
Proteasome subunit beta type-3	Homo sapiens (human)	1.9893
Proteasome subunit beta type-2	Homo sapiens (human)	2.0443
Proteasome subunit alpha type-6	Homo sapiens (human)	1.9893
Proteasome subunit alpha-type 8	Homo sapiens (human)	1.9893
Proteasome subunit beta type-7	Homo sapiens (human)	1.9893

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bennink, JR; Chen, W; Crews, CM; Myung, J; Princiotta, MF; Schubert, U; Yewdell, JW	1
Chikuma, T; Hojo, H; Tsuchiya, Y; Yamaguchi, M	1

Other Studies

2 other study(ies) available for alanyl-alanyl-phenylalanine chloromethyl ketone and benzyloxycarbonylleucyl-leucyl-leucine aldehyde

Article	Year
Cells adapted to the proteasome inhibitor 4-hydroxy- 5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival. Proceedings of the National Academy of Sciences of the United States of America, 2001, Jan-16, Volume: 98, Issue:2 Topics: Amino Acid Chloromethyl Ketones; Aminopeptidases; Animals; Antigen Presentation; Antigens; Boronic Acids; Bortezomib; CD8-Positive T-Lymphocytes; Cell Survival; Cysteine Endopeptidases; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Drug Resistance; Endopeptidases; Enzyme Activation; H-2 Antigens; Leupeptins; Lymphoma, T-Cell; Mice; Multienzyme Complexes; Neoplasm Proteins; Oligopeptides; Peptide Fragments; Phenols; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Pyrazines; Selection, Genetic; Serine Endopeptidases; Sulfones; Thymus Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tyramine; Ubiquitins	2001
Degradation of glyceraldehyde-3-phosphate dehydrogenase triggered by 4-hydroxy-2-nonenal and 4-hydroxy-2-hexenal. Archives of biochemistry and biophysics, 2005, Jun-15, Volume: 438, Issue:2 Topics: Aldehydes; Amino Acid Chloromethyl Ketones; Blotting, Western; Chromatography, Gel; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Leupeptins; Lipid Peroxidation; Oxidative Stress; Phenylmethylsulfonyl Fluoride; Proteasome Endopeptidase Complex; Sepharose; Serine Endopeptidases; Time Factors; U937 Cells	2005

Article

Year

Cells adapted to the proteasome inhibitor 4-hydroxy- 5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival.

Proceedings of the National Academy of Sciences of the United States of America, 2001, Jan-16, Volume: 98, Issue:2

Topics: Amino Acid Chloromethyl Ketones; Aminopeptidases; Animals; Antigen Presentation; Antigens; Boronic Acids; Bortezomib; CD8-Positive T-Lymphocytes; Cell Survival; Cysteine Endopeptidases; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Drug Resistance; Endopeptidases; Enzyme Activation; H-2 Antigens; Leupeptins; Lymphoma, T-Cell; Mice; Multienzyme Complexes; Neoplasm Proteins; Oligopeptides; Peptide Fragments; Phenols; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Pyrazines; Selection, Genetic; Serine Endopeptidases; Sulfones; Thymus Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tyramine; Ubiquitins

2001

Degradation of glyceraldehyde-3-phosphate dehydrogenase triggered by 4-hydroxy-2-nonenal and 4-hydroxy-2-hexenal.

Archives of biochemistry and biophysics, 2005, Jun-15, Volume: 438, Issue:2

Topics: Aldehydes; Amino Acid Chloromethyl Ketones; Blotting, Western; Chromatography, Gel; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Leupeptins; Lipid Peroxidation; Oxidative Stress; Phenylmethylsulfonyl Fluoride; Proteasome Endopeptidase Complex; Sepharose; Serine Endopeptidases; Time Factors; U937 Cells

2005