Page last updated: 2024-08-25

alantolactone and sesquiterpenes

alantolactone has been researched along with sesquiterpenes in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19907 (22.58)18.7374
1990's7 (22.58)18.2507
2000's1 (3.23)29.6817
2010's11 (35.48)24.3611
2020's5 (16.13)2.80

Authors

AuthorsStudies
Brisson, J; Dupuis, G1
Alonso Blasi, N; Benezra, C; Fraginals, R; Lepoittevin, JP1
Benezra, C; Blasi, NA; Fraginals, R; Lepoittevin, JP1
Picman, AK; Picman, J1
Chaney, SG; Chapman, DE; Hall, IH; Holbrook, DJ; Lee, KH1
Gonzalez de Canales, F; Hausen, BM; Hinojosa, JL; Llamas, P; Pinedo, JM1
Azoulay, P; Balansard, G; Gasquet, M; Reynier, JP; Timon-David, P1
Benezra, C; Geleick, H; Hausen, B; Klecak, G; Schulz, KH; Stampf, JL1
Benezra, C; Gabriel-Robez, O; Grosshans, E; Schlewer, G; Stampf, JL1
Muro, MD; Olaguibel, JM; Quirce, S; Tabar, AI1
du Peloux Menagé, H; Hawk, JL; Ross, JS; White, IR1
de la Cuadra, J; Mateo, MP; Miquel, FJ; Velasco, M1
Kawabe, Y; Kuno, Y; Sakakibara, S1
Alanko, K; Estlander, T; Jolanki, R; Kanerva, L1
Huo, Y; Li, W; Li, X; Shi, H; Wang, M1
Becnel, JJ; Cantrell, CL; Fronczek, FR; Pridgeon, JW1
Ali, M; Khan, M; Li, J; Li, X; Rasul, A1
Guo, C; Niu, K; Teng, S; Zhang, S1
Jeong, SJ; Jin, SE; Kim, OS; Lim, HS; Shin, HK1
Li, X; Peng, Y; Wang, M; Xu, R; Zhou, G1
Kim, J; Kim, JS; Lee, KW; Lim, SS; Seo, JY1
Hwang, J; Im, DS; Kang, S; Lee, BK; Lee, SJ; Nam, SY; Park, SJ1
Chen, L; Ge, G; Lan, G; Liu, Q; Mao, L; Ning, J; Shen, Y; Wang, S; Yang, L; Yang, N; Ye, J; Zhang, W; Zhou, B; Zhuo, Z1
Bi, Z; Gao, S; Huang, K; Huang, M; Li, X; Liu, N; Liu, S; Liu, T; Liu, X; Lu, C; Mao, J; Miao, S; Ning, W; Qi, M; Qin, S; Sheng, P; Su, C; Sun, T; Wei, L; Wei, Y; Xiao, T; Yang, C; Yang, G; Zhao, L; Zhou, H1
Li, X; Peng, Y; Wang, M; Xu, R1
Amaro-Luis, JM; Chacón-Morales, PA; Dugarte, CS1
Larrosa, I; Osborne, HC; Schmidt, CK1
Jeon, CH; Jeong, YJ; Jung, YS; Kim, JH; Lee, SO1
Lattoo, SK; Mudassir Jeelani, S; Prakash Gupta, A; Shahnawaz, M1
Aleksandrova, YR; Artyushin, OI; Brel, VK; Neganova, ME; Nikolaeva, NS; Sharova, EV; Smirnova, EV; Yandulova, EY1

Reviews

1 review(s) available for alantolactone and sesquiterpenes

ArticleYear
Targeting apoptosis pathways in cancer with alantolactone and isoalantolactone.
    TheScientificWorldJournal, 2013, Volume: 2013

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Humans; Lactones; Neoplasm Proteins; Neoplasms; Sesquiterpenes; Sesquiterpenes, Eudesmane

2013

Other Studies

30 other study(ies) available for alantolactone and sesquiterpenes

ArticleYear
Alantolactone in chrysanthemum extract.
    Contact dermatitis, 1978, Volume: 4, Issue:6

    Topics: Chrysanthemum cinerariifolium; Dermatitis, Contact; Humans; Lactones; Plant Extracts; Sesquiterpenes; Sesquiterpenes, Eudesmane

1978
Toxic effect of alantolactone and dihydroalantolactone in in vitro cultures of leukocytes.
    Chemico-biological interactions, 1976, Volume: 15, Issue:3

    Topics: Benzofurans; Cells, Cultured; DNA Replication; Kinetics; Lactones; Lectins; Lymphocyte Activation; Lymphocytes; Sesquiterpenes; Sesquiterpenes, Eudesmane; Thymidine

1976
A murine in vitro model of allergic contact dermatitis to sesquiterpene alpha-methylene-gamma-butyrolactones.
    Archives of dermatological research, 1992, Volume: 284, Issue:5

    Topics: Animals; Cross Reactions; Dermatitis, Allergic Contact; Disease Models, Animal; In Vitro Techniques; Lactones; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Sesquiterpenes; Sesquiterpenes, Eudesmane; Species Specificity

1992
A successful murine model for contact sensitization to a sesquiterpene-alpha-methylene-gamma-butyrolactone: sensitization to alantolactone in four strains of mice.
    The Journal of investigative dermatology, 1991, Volume: 97, Issue:3

    Topics: Animals; Dermatitis, Atopic; Dermatitis, Contact; Edema; Lactones; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred DBA; Mice, Inbred Strains; Sesquiterpenes; Sesquiterpenes, Eudesmane; Skin

1991
Treatment of dermatitis caused by the sesquiterpene lactone helenin.
    Die Pharmazie, 1990, Volume: 45, Issue:1

    Topics: Animals; Cysteine; Dermatitis, Contact; Female; Guinea Pigs; Lactones; Sesquiterpenes; Sesquiterpenes, Eudesmane

1990
In vitro inhibition of mouse hepatic mixed-function oxidase enzymes by helenalin and alantolactone.
    Biochemical pharmacology, 1989, Nov-15, Volume: 38, Issue:22

    Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ethylmaleimide; Glutathione; Lactones; Liver; Male; Mice; NADP; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Sesquiterpenes; Sesquiterpenes, Eudesmane; Sesquiterpenes, Guaiane; Toxins, Biological

1989
Contact dermatitis to sesquiterpene lactones in Inula viscosa Aiton.
    Contact dermatitis, 1987, Volume: 17, Issue:5

    Topics: Adult; Benzofurans; Dermatitis, Contact; Female; Flavonoids; Hand Dermatoses; Humans; Inula; Lactones; Patch Tests; Plant Extracts; Sesquiterpenes; Sesquiterpenes, Eudesmane; Skin Diseases, Vesiculobullous

1987
[Helenine and santonine, the 12-carboxy-eudesma-3,11(13) diene].
    Pharmaceutica acta Helvetiae, 1986, Volume: 61, Issue:12

    Topics: Animals; Anthelmintics; Lactones; Plant Extracts; Plants, Medicinal; Santonin; Sesquiterpenes; Sesquiterpenes, Eudesmane

1986
The sensitizing capacity of helenin and of two of its main constituents, the sesquiterpene lactones alantolactone and isoalantolactone: a comparison of epicutaneous and intradermal sensitizing methods in different strains of guinea pig.
    Contact dermatitis, 1982, Volume: 8, Issue:1

    Topics: Administration, Topical; Animals; Dermatitis, Contact; Female; Guinea Pigs; Injections, Intradermal; Lactones; Sesquiterpenes; Sesquiterpenes, Eudesmane

1982
Allergic contact dermatitis to methylenelactones. Use of lymphocyte transformation test.
    Archives of dermatological research, 1982, Volume: 272, Issue:1-2

    Topics: Allergens; Animals; Cells, Cultured; Chemical Phenomena; Chemistry; Dermatitis, Atopic; Dermatitis, Contact; Guinea Pigs; Lactones; Lymphocyte Activation; Methods; Sesquiterpenes; Sesquiterpenes, Eudesmane

1982
Airborne contact dermatitis from Frullania.
    Contact dermatitis, 1994, Volume: 30, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Benzoquinones; Dermatitis, Allergic Contact; Diagnosis, Differential; Female; Humans; Lactones; Male; Middle Aged; Patch Tests; Photosensitivity Disorders; Plants; Sesquiterpenes; Sesquiterpenes, Eudesmane

1994
Sesquiterpene lactone contact sensitivity: clinical patterns of Compositae dermatitis and relationship to chronic actinic dermatitis.
    Contact dermatitis, 1993, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chronic Disease; Dermatitis, Allergic Contact; Female; Humans; Lactones; Male; Middle Aged; Photosensitivity Disorders; Plants; Sesquiterpenes; Sesquiterpenes, Eudesmane

1993
Erythema-multiforme-like eruption following allergic contact dermatitis from sesquiterpene lactones in herbal medicine.
    Contact dermatitis, 1995, Volume: 33, Issue:6

    Topics: Adult; Chromates; Dermatitis, Allergic Contact; Drug Eruptions; Erythema Multiforme; Female; Humans; Lactones; Nickel; Phytotherapy; Plant Extracts; Sesquiterpenes; Sesquiterpenes, Eudesmane

1995
Allergic contact dermatitis associated with photosensitivity, from alantolactone in a chrysanthemum farmer.
    Contact dermatitis, 1999, Volume: 40, Issue:4

    Topics: Agricultural Workers' Diseases; Animals; Dermatitis, Occupational; Dermatitis, Photoallergic; Humans; Lactones; Male; Middle Aged; Patch Tests; Plants; Sesquiterpenes; Sesquiterpenes, Eudesmane

1999
Patch test sensitization to Compositae mix, sesquiterpene-lactone mix, Compositae extracts, laurel leaf, Chlorophorin, Mansonone A, and dimethoxydalbergione.
    American journal of contact dermatitis : official journal of the American Contact Dermatitis Society, 2001, Volume: 12, Issue:1

    Topics: Adult; Allergens; Asteraceae; Benzoquinones; Dermatitis, Allergic Contact; Female; Humans; Lactones; Male; Naphthoquinones; Patch Tests; Plant Extracts; Predictive Value of Tests; Resorcinols; Sesquiterpenes; Sesquiterpenes, Eudesmane; Stilbenes

2001
HPLC determination and NMR structural elucidation of sesquiterpene lactones in Inula helenium.
    Journal of pharmaceutical and biomedical analysis, 2010, Mar-11, Volume: 51, Issue:4

    Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Inula; Isomerism; Lactones; Magnetic Resonance Spectroscopy; Molecular Structure; Reproducibility of Results; Sesquiterpenes; Sesquiterpenes, Eudesmane

2010
Structure-activity relationship studies on derivatives of eudesmanolides from Inula helenium as toxicants against Aedes aegypti larvae and adults.
    Chemistry & biodiversity, 2010, Volume: 7, Issue:7

    Topics: Aedes; Animals; Crystallography, X-Ray; Insecticides; Inula; Lactones; Larva; Models, Molecular; Sesquiterpenes; Sesquiterpenes, Eudesmane; Structure-Activity Relationship

2010
Simultaneous determination of sesquiterpene lactones isoalantolactone and alantolactone isomers in rat plasma by liquid chromatography with tandem mass spectrometry: application to a pharmacokinetic study.
    Journal of separation science, 2014, Volume: 37, Issue:8

    Topics: Animals; Chromatography, Liquid; Lactones; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Sesquiterpenes, Eudesmane; Stereoisomerism; Tandem Mass Spectrometry

2014
Alantolactone from Saussurea lappa Exerts Antiinflammatory Effects by Inhibiting Chemokine Production and STAT1 Phosphorylation in TNF-α and IFN-γ-induced in HaCaT cells.
    Phytotherapy research : PTR, 2015, Volume: 29, Issue:7

    Topics: Anti-Inflammatory Agents; Cell Line; Chemokine CCL17; Chemokine CCL22; Chemokine CCL5; Chemokines; Enzyme-Linked Immunosorbent Assay; Humans; Interferon-gamma; Interleukin-8; Keratinocytes; Lactones; Phosphorylation; Plant Extracts; Polycyclic Sesquiterpenes; Saussurea; Sesquiterpenes; Sesquiterpenes, Eudesmane; STAT1 Transcription Factor; STAT5 Transcription Factor; Tumor Necrosis Factor-alpha; Tumor Suppressor Proteins

2015
Pharmacokinetics, tissue distribution and excretion of isoalantolactone and alantolactone in rats after oral administration of Radix Inulae extract.
    Molecules (Basel, Switzerland), 2015, Apr-28, Volume: 20, Issue:5

    Topics: Administration, Oral; Animals; Chromatography, Liquid; Gastropoda; Lactones; Male; Medicine, Chinese Traditional; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Sesquiterpenes, Eudesmane; Tandem Mass Spectrometry; Tissue Extracts

2015
Alantolactone and Isoalantolactone Prevent Amyloid β
    Phytotherapy research : PTR, 2017, Volume: 31, Issue:5

    Topics: Amyloid beta-Peptides; Animals; Avoidance Learning; Cognition Disorders; Cognitive Dysfunction; Lactones; Male; Maze Learning; Memory Disorders; Mice; Neurons; Neuroprotective Agents; Peptide Fragments; Scopolamine; Sesquiterpenes; Sesquiterpenes, Eudesmane

2017
Anti-allergic effects of sesquiterpene lactones from Saussurea costus (Falc.) Lipsch. determined using in vivo and in vitro experiments.
    Journal of ethnopharmacology, 2018, Mar-01, Volume: 213

    Topics: Animals; Anti-Allergic Agents; Bronchoalveolar Lavage Fluid; Cell Degranulation; Cells, Cultured; Dose-Response Relationship, Drug; Female; Interleukin-13; Interleukin-4; Lactones; Lung; Mast Cells; Mice; Mucins; Plant Roots; Rats; Saussurea; Sesquiterpenes; Sesquiterpenes, Eudesmane

2018
Metabolism and pharmacokinetics of alantolactone and isoalantolactone in rats: Thiol conjugation as a potential metabolic pathway.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018, Jan-01, Volume: 1072

    Topics: Animals; Chromatography, Liquid; Cysteine; Glutathione; Humans; Lactones; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Sesquiterpenes, Eudesmane; Sulfhydryl Compounds; Tandem Mass Spectrometry

2018
Synthesis and discovery of a drug candidate for treatment of idiopathic pulmonary fibrosis through inhibition of TGF-β1 pathway.
    European journal of medicinal chemistry, 2018, Sep-05, Volume: 157

    Topics: Animals; Bleomycin; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Fibroblasts; High-Throughput Screening Assays; Idiopathic Pulmonary Fibrosis; Lactones; Mice; Molecular Structure; NIH 3T3 Cells; Sesquiterpenes; Sesquiterpenes, Eudesmane; Structure-Activity Relationship; Transforming Growth Factor beta1

2018
Intestinal Absorption of Isoalantolactone and Alantolactone, Two Sesquiterpene Lactones from Radix Inulae, Using Caco-2 Cells.
    European journal of drug metabolism and pharmacokinetics, 2019, Volume: 44, Issue:2

    Topics: Administration, Oral; Biological Availability; Caco-2 Cells; Dose-Response Relationship, Drug; Humans; Intestinal Absorption; Inula; Lactones; Permeability; Plant Roots; Sesquiterpenes; Sesquiterpenes, Eudesmane

2019
Helenin from
    Natural product research, 2021, Volume: 35, Issue:21

    Topics: Lactones; Sesquiterpenes; Sesquiterpenes, Eudesmane; Stevia

2021
Sesquiterpene Lactones Potentiate Olaparib-Induced DNA Damage in p53 Wildtype Cancer Cells.
    International journal of molecular sciences, 2022, Jan-20, Volume: 23, Issue:3

    Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromosomal Instability; Dose-Response Relationship, Drug; Drug Synergism; Humans; Lactones; Neoplasms; Oxidative Stress; Phthalazines; Piperazines; Pyrazoles; Pyrimidinones; Sesquiterpenes; Sesquiterpenes, Eudesmane; Tumor Suppressor Protein p53

2022
Elecampane (
    Molecules (Basel, Switzerland), 2022, Jul-25, Volume: 27, Issue:15

    Topics: 3T3-L1 Cells; Adipogenesis; AMP-Activated Protein Kinases; Animals; Cell Differentiation; Inula; Lactones; Mice; Phytochemicals; Plant Extracts; Sesquiterpenes; Sesquiterpenes, Eudesmane

2022
Phytochemical Diversity in Relation to Cytogenetic Variability in Inula racemosa Hook.f., an Endangered Medicinal Plant of Himalayas.
    Chemistry & biodiversity, 2022, Volume: 19, Issue:12

    Topics: Chromatography, Liquid; Cytogenetic Analysis; Humans; Inula; Phytochemicals; Plants, Medicinal; Sesquiterpenes; Tandem Mass Spectrometry; Tetraploidy

2022
Design of Conjugates Based on Sesquiterpene Lactones with Polyalkoxybenzenes by "Click" Chemistry to Create Potential Anticancer Agents.
    Molecules (Basel, Switzerland), 2022, Dec-01, Volume: 27, Issue:23

    Topics: Antineoplastic Agents; Click Chemistry; HEK293 Cells; Humans; Lactones; Neuroblastoma; Phytochemicals; Sesquiterpenes

2022