alanine and vancomycin

alanine has been researched along with vancomycin in 71 studies

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-199024 (33.80)18.7374
1990's12 (16.90)18.2507
2000's21 (29.58)29.6817
2010's11 (15.49)24.3611
2020's3 (4.23)2.80

Authors

AuthorsStudies
Brown, JP; Burgen, AS; Feeney, J1
Hebeler, BH; Young, FE1
Daneo-Moore, L; Jungkind, D; Rosenthal, RS; Shockman, GD1
Brown, JP; Burgen, AS; Feeney, J; Terenius, L1
Hawkes, GE; Lian, LY; Molinari, H; Pastore, A; Sales, K1
Bisaillon, JG; de Repentigny, J; Mathieu, LG2
Reynolds, PE2
Ward, JB1
Bracha, R; Mirelman, D; Sharon, N1
De Haas-Menger, L; Lugtenberg, EJ; Ruyters, WH1
Borowski, E; Chmara, H2
Nieto, M; Perkins, HR; Reynolds, PE1
Grula, EA; King, RD1
Nieto, M; Perkins, HR3
Neuhaus, RC; Sinha, RK1
Chatterjee, AN; Perkins, HR1
Chatterjee, AN; Tuazon, CU; Wong, W; Young, FE; Zeiger, AR1
Arthur, M; Courvalin, P; Depardieu, F; Reynolds, PE; Snaith, HA1
Arthur, M; Courvalin, P; Depardieu, F; Dutka-Malen, S; Reynolds, PE1
Arthur, M; Courvalin, P; Depardieu, F; Molinas, C1
Lin, CH; Park, IS; Walsh, CT1
Bierbaum, G; Brötz, H; Jack, R; Kluczny, C; Molitor, E; Sahl, HG1
Park, IS; Walsh, CT1
Cornish, N; Hall, GS; Knapp, CC; Ludwig, MD; Sng, LH; Washington, JA1
Isaacs, L; Lahiri, J; Rao, J; Weis, RM; Whitesides, GM1
Bussiere, DE; Holzman, T; Katz, L; Park, CH; Pratt, SD; Severin, JM1
Axelsen, PH; Li, D1
Healy, VL; Lessard, IA; Park, IS; Walsh, CT1
Aihara, Y; Fukamachi, K; Hori, T; Imamura, T; Kasuya, H; Kawashima, A; Kikuchi, K; Ochiai, T; Shiseki, M; Tozuka, K; Yamaguchi, K1
Casnati, A; Cohen, Y; Frish, L; Sansone, F; Ungaro, R1
Götz, F; Otto, M; Peschel, A; Vuong, C1
Abell, C; Cooper, MA; Fiorini, MT; Williams, DH1
Gutheil, WG; Nicholas, RA; Stefanova, ME1
Boneca, IG; Chiosis, G1
Grosset, C; Peyrin, E; Ravel, A; Ravelet, C; Slama, I; Villet, A1
Axelsen, PH; Jusuf, S; Loll, PJ1
Cegelski, L; Hing, AW; Kim, SJ; Mehta, AK; O'Connor, RD; Schaefer, J; Studelska, DR1
Casnati, A; Sansone, F; Ungaro, R1
Cegelski, L; Mehta, AK; O'Connor, RD; Schaefer, J1
Ellman, JA; Jain, RK; Trias, J1
BEST, GK; DURHAM, NN1
DOBSON, MB; DURHAM, NN; FERGUSON, D; KUDLAC, JJ1
DURHAM, NN; FERGUSON, D; JACOBS, CD1
Lee, JG; Roland, C; Sagui, C1
Huskens, J; Mulder, A; Reinhoudt, DN1
Bandur, N; Finking, R; Koert, U; Marahiel, MA; May, JJ; Weber, TT; Wiegeshoff, F1
Boyd, DA; Miller, MA; Mulvey, MR1
Boger, DL; Crowley, BM1
Cegelski, L; Kim, SJ; Preobrazhenskaya, M; Schaefer, J1
Chang, YP; Chu, YH; Tseng, MC1
Breukink, E; de Kruijff, B; Hartung, T; Hasper, HE; Kok, J; Kramer, NE; Kuipers, OP; Morath, S; Smid, EJ; van den Bogaard, PTC1
Aboul-Enein, HY; Alizadeh, R; Ghassempour, A; Karami, A; Najafi, NM; Römpp, A; Spengler, B1
Bobba, S; Gutheil, WG; Putty, S; Vemula, H1
Courvalin, P; Evdokimova, E; Meziane-Cherif, D; Savchenko, A; Stogios, PJ1
Boger, DL; Nakayama, A; Okano, A; Schammel, AW1
Delcour, AH; Farabella, I; Geibel, S; Henderson, NS; Pham, T; Phan, G; Thanassi, DG; Topf, M; Waksman, G1
Fan, H; Fryčák, P; Mesquita, RB; Ramirez, S; Rangel, AO; Santos, IC; Schug, KA; Waybright, VB1
Butel, MJ; Lai-Kuen, R; Louis, M; Pons, JL; Saubaméa, B; Wydau-Dematteis, S; Zahr, N1
Cegelski, L; Romaniuk, JA1
Lemmens, N; van der Aart, LT; van Wamel, WJ; van Wezel, GP1
Chang, JD; Foster, EE; Kim, SJ; Yang, H1
Chang, J; Coffman, L; Kim, SJ; Singh, M1
Balakrishna, AM; Eisenhaber, B; Eisenhaber, F; Grüber, A; Grüber, G; Kamariah, N; Shin, J; Toh, YK1
Liang, Y; Wang, Q; Yan, X; Yang, L; Zhao, W1
Bai, J; Chen, X; Geng, D; Guo, Q; He, W; Li, B; Pan, G; Suo, D; Wang, M; Wang, S; Yin, W; Zhao, X1
Choi, U; Lee, CR; Lee, HB; Lee, JW; Park, SH; Ryu, SH1

Reviews

3 review(s) available for alanine and vancomycin

ArticleYear
Peptido- and glycocalixarenes: playing with hydrogen bonds around hydrophobic cavities.
    Accounts of chemical research, 2003, Volume: 36, Issue:4

    Topics: Alanine; Calixarenes; Crystallography, X-Ray; Glycosides; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ionophores; Ligands; Macromolecular Substances; Models, Molecular; Molecular Conformation; Molecular Mimicry; Peptides; Phenols; Vancomycin

2003
Multivalency in supramolecular chemistry and nanofabrication.
    Organic & biomolecular chemistry, 2004, Dec-07, Volume: 2, Issue:23

    Topics: Alanine; Cyclodextrins; Nanotechnology; Vancomycin

2004
Bacterial cell wall composition and the influence of antibiotics by cell-wall and whole-cell NMR.
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2015, Oct-05, Volume: 370, Issue:1679

    Topics: Alanine; Anti-Bacterial Agents; Cell Wall; Glycopeptides; Lipoglycopeptides; Lysine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Peptidoglycan; Staphylococcus aureus; Vancomycin

2015

Other Studies

68 other study(ies) available for alanine and vancomycin

ArticleYear
A nuclear magnetic resonance study of the interaction between vanomycin and acetyl-D-alanyl-D-alanine in aqueous solution.
    Molecular pharmacology, 1975, Volume: 11, Issue:2

    Topics: Alanine; Chemical Phenomena; Chemistry; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Peptide Chain Termination, Translational; Peptides; Protein Binding; Temperature; Urea; Vancomycin

1975
Autolysis of Neisseria gonorrhoeae.
    Journal of bacteriology, 1975, Volume: 122, Issue:2

    Topics: Alanine; Bacteriolysis; Cell Fractionation; Cell Wall; Chromatography, Paper; Cycloserine; Diaminopimelic Acid; Glucosamine; Hydrogen-Ion Concentration; Neisseria gonorrhoeae; Penicillins; Peptidoglycan; Potassium; Temperature; Vancomycin

1975
Evidence for the synthesis of soluble peptidoglycan fragments by protoplasts of Streptococcus faecalis.
    Journal of bacteriology, 1975, Volume: 124, Issue:1

    Topics: Acetates; Alanine; Cycloserine; Enterococcus faecalis; Hydrolysis; Lysine; Muramidase; Peptide Biosynthesis; Peptidoglycan; Pronase; Protoplasts; Solubility; Stereoisomerism; Tetracycline; Tritium; Vancomycin

1975
A structure-activity study by nuclear magnetic resonance of peptide interactions with vancomycin.
    Molecular pharmacology, 1975, Volume: 11, Issue:2

    Topics: Alanine; Binding Sites; Magnetic Resonance Spectroscopy; Molecular Conformation; Peptide Chain Termination, Translational; Peptides; Structure-Activity Relationship; Vancomycin

1975
Structure of vancomycin and a vancomycin/D-Ala-D-Ala complex in solution.
    Biochemistry, 1990, Mar-06, Volume: 29, Issue:9

    Topics: Alanine; Chemical Phenomena; Chemistry, Physical; Dipeptides; Magnetic Resonance Spectroscopy; Molecular Structure; Solutions; Spectrum Analysis; Vancomycin

1990
Effects of wall inhibitors on thymineless Streptococcus faecalis.
    Canadian journal of microbiology, 1974, Volume: 20, Issue:8

    Topics: Alanine; Aminopterin; Anti-Bacterial Agents; Bacitracin; Cell Wall; Cycloserine; Enterococcus faecalis; Mutation; Penicillins; Stereoisomerism; Thymine; Vancomycin

1974
Peptidoglycan synthesis in bacilli. I. Effect of temperature on the in vitro system from Bacillus megaterium and Bacillus stearothermophilus.
    Biochimica et biophysica acta, 1971, May-18, Volume: 237, Issue:2

    Topics: Alanine; Bacillus; Bacillus megaterium; Bacitracin; Carbon Isotopes; Carboxypeptidases; Cell Fractionation; Cell Membrane; Cell Wall; Cell-Free System; Chlorides; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Drug Stability; Glucosamine; Glycosaminoglycans; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methods; Micrococcus; Muramidase; Nucleoside Diphosphate Sugars; Peptide Biosynthesis; Pimelic Acids; Polysaccharides, Bacterial; Staphylococcus; Temperature; Terpenes; Tritium; Uracil Nucleotides; Vancomycin

1971
Peptidoglycan synthesis in bacilli. II. Characteristics of protoplast membrane preparations.
    Biochimica et biophysica acta, 1971, May-18, Volume: 237, Issue:2

    Topics: Alanine; Amino Acids; Autoradiography; Bacillus megaterium; Bacitracin; Carbon Isotopes; Cell Membrane; Chloramphenicol; Chlorides; Chromatography, Paper; Edetic Acid; Glucosamine; Glycosaminoglycans; Hydrochloric Acid; Kinetics; Macromolecular Substances; Magnesium; Muramidase; Nucleoside Diphosphate Sugars; Osmotic Pressure; Penicillins; Peptides; Pimelic Acids; Polysaccharides, Bacterial; Protoplasts; Temperature; Time Factors; Tritium; Tromethamine; Uracil Nucleotides; Vancomycin

1971
The synthesis of peptidoglycan in an autolysin-deficient mutant of Bacillus licheniformis N.C.T.C. 6346 and the effect of beta-lactam antibiotics, bacitracin and vancomycin.
    The Biochemical journal, 1974, Volume: 141, Issue:1

    Topics: Alanine; Anti-Bacterial Agents; Bacillus; Bacitracin; Carboxypeptidases; Cell Membrane; Cell Wall; Cephalosporins; Chromatography, Paper; Electrophoresis, Paper; Hydroxylamines; Mutation; Penicillins; Peptidoglycan; Temperature; Vancomycin

1974
Studies on the elongation of bacterial cell wall peptidoglycan and its inhibition by penicillin.
    Annals of the New York Academy of Sciences, 1974, May-10, Volume: 235, Issue:0

    Topics: Adenosine Triphosphate; Alanine; Amino Acids; Bacterial Proteins; Carbon Radioisotopes; Cell Membrane; Cell Wall; Chromatography, Paper; Deoxycholic Acid; Lysine; Micrococcus; Molecular Weight; Muramidase; Nucleotides; Penicillin G; Penicillins; Peptide Chain Elongation, Translational; Peptidoglycan; Pronase; Sodium Dodecyl Sulfate; Taurocholic Acid; Vancomycin

1974
Murein synthesis and identification of cell wall precursors of temperature-sensitive lysis mutants of Escherichia coli.
    Journal of bacteriology, 1972, Volume: 109, Issue:1

    Topics: Alanine; Autoradiography; Bacterial Proteins; Bacteriolysis; Carbon Isotopes; Cell Wall; Chromatography, Paper; Culture Media; Escherichia coli; Mutagens; Mutation; Nitrosoguanidines; Osmotic Pressure; Penicillins; Peptide Biosynthesis; Peptides; Peptidoglycan; Sodium Chloride; Spectrophotometry; Sucrose; Temperature; Vancomycin

1972
Antibiotic tetaine, a new inhibitor of murein precursors synthesis in Escherichia coli K-12.
    Biochemical and biophysical research communications, 1973, Jun-19, Volume: 52, Issue:4

    Topics: Alanine; Amino Acids; Ampicillin; Anti-Bacterial Agents; Bacitracin; Carbon Isotopes; Chromatography, Paper; Cycloserine; Escherichia coli; Kinetics; Lipids; Muramic Acids; Penicillins; Peptidoglycan; Pimelic Acids; Tritium; Uridine; Uridine Diphosphate Sugars; Vancomycin

1973
Morphological changes induced by wall inhibitors in pyogenic cocci.
    Revue canadienne de biologie, 1973, Volume: 32, Issue:2

    Topics: Alanine; Anti-Bacterial Agents; Bacitracin; Cell Wall; Cycloserine; Penicillin G; Staphylococcus aureus; Streptococcus; Streptococcus pyogenes; Vancomycin

1973
Reversal by a specific peptide (diacetyl-alpha gamma-L-diaminobutyryl-D-alanyl-D-alanine) of vancomycin inhibition in intact bacteria and cell-free preparations.
    The Biochemical journal, 1972, Volume: 126, Issue:1

    Topics: Alanine; Aminobutyrates; Bacillus megaterium; Bacteria; Cell-Free System; Iodine Isotopes; Micrococcus; Mucoproteins; Oligopeptides; Staphylococcus; Vancomycin

1972
The inhibition of murein synthesis in Staphylococcus aureus by the antibiotic tetaine.
    Biochemical and biophysical research communications, 1973, Dec-19, Volume: 55, Issue:4

    Topics: Alanine; Anti-Bacterial Agents; Biological Transport; Chromatography, Paper; Cycloserine; Dipeptides; Lipids; Lysine; Methicillin; Muramic Acids; Oligopeptides; Peptide Synthases; Peptidoglycan; Staphylococcus; Tritium; Uridine Diphosphate Sugars; Vancomycin

1973
Condition of cell-wall mucopeptide in dividing and non-dividing cells of Micrococcus lysodeikticus dis-IIp + .
    Canadian journal of microbiology, 1972, Volume: 18, Issue:4

    Topics: Alanine; Amino Acids; Amino Sugars; Carbon Isotopes; Cell Division; Cell Wall; Chromatography, Thin Layer; Cycloserine; Histocytochemistry; Hydroxylamines; Lactones; Micrococcus; Microscopy, Electron; Mitomycins; Penicillins; Peptide Biosynthesis; Peptides; Serine; Spermine; Stereoisomerism; Vancomycin

1972
Physicochemical properties of vancomycin and iodovancomycin and their complexes with diacetyl-L-lysyl-D-alanyl-D-alanine.
    The Biochemical journal, 1971, Volume: 123, Issue:5

    Topics: Alanine; Binding Sites; Circular Dichroism; Iodides; Lysine; Macromolecular Substances; Optical Rotatory Dispersion; Peptides; Potassium Chloride; Spectrophotometry; Surface-Active Agents; Urea; Vancomycin

1971
Modifications of the acyl-D-alanyl-D-alanine terminus affecting complex-formation with vancomycin.
    The Biochemical journal, 1971, Volume: 123, Issue:5

    Topics: Alanine; Amides; Binding Sites; Carboxylic Acids; Chromatography; Electrophoresis; Glutamates; Glycine; Peptides; Spectrophotometry; Vancomycin

1971
The preparation of iodinated vancomycin and its distribution in bacteria treated with the antibiotic.
    The Biochemical journal, 1970, Volume: 116, Issue:1

    Topics: Adsorption; Alanine; Bacillus; Cell Membrane; Cell Wall; Chromatography, Paper; Iodine Isotopes; Magnesium; Micrococcus; Mucoproteins; Protoplasts; Vancomycin

1970
Reversal of the vancomycin inhibition of peptidoglycan synthesis by cell walls.
    Journal of bacteriology, 1968, Volume: 96, Issue:2

    Topics: Adsorption; Alanine; Amino Sugars; Bacitracin; Carbon Isotopes; Cell Wall; Cell-Free System; Lipid Metabolism; Magnesium; Manganese; Micrococcus; Mucoproteins; Peptide Biosynthesis; Peptides; Phosphotransferases; Ristocetin; Staphylococcus; Vancomycin

1968
Compounds formed between nucleotides related to the biosynthesis of bacterial cell wall and vancomycin.
    Biochemical and biophysical research communications, 1966, Aug-12, Volume: 24, Issue:3

    Topics: Alanine; Amino Acids; Aspartic Acid; Cell Wall; Chromatography, Paper; Corynebacterium; Glutamates; Glycine; Lysine; Nucleotides; Ornithine; Staphylococcus; Uracil Nucleotides; Vancomycin

1966
Evidence for the secretion of soluble peptidoglycans by clinical isolates of Staphylococcus aureus.
    Infection and immunity, 1982, Volume: 37, Issue:3

    Topics: Alanine; Culture Media; Dose-Response Relationship, Drug; Endocarditis, Bacterial; Humans; Penicillin G; Peptidoglycan; Staphylococcal Infections; Staphylococcus aureus; Vancomycin

1982
Contribution of VanY D,D-carboxypeptidase to glycopeptide resistance in Enterococcus faecalis by hydrolysis of peptidoglycan precursors.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:9

    Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Carbon-Oxygen Ligases; Carboxypeptidases; Cell Wall; Drug Resistance, Microbial; Enterococcus faecalis; Glycopeptides; Hydrolysis; Ligases; Molecular Sequence Data; Peptidoglycan; Phenotype; Vancomycin

1994
Glycopeptide resistance mediated by enterococcal transposon Tn1546 requires production of VanX for hydrolysis of D-alanyl-D-alanine.
    Molecular microbiology, 1994, Volume: 13, Issue:6

    Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Carbon-Oxygen Ligases; Dipeptides; DNA Transposable Elements; Drug Resistance, Microbial; Enterococcus faecium; Gene Expression Regulation, Bacterial; Genes, Bacterial; Hydrolysis; Lactates; Ligases; Molecular Sequence Data; Peptidoglycan; Protein Kinases; Pyruvates; Pyruvic Acid; Serine-Type D-Ala-D-Ala Carboxypeptidase; Teicoplanin; Transcription Factors; Vancomycin

1994
Characterization of Tn1546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147.
    Journal of bacteriology, 1993, Volume: 175, Issue:1

    Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; Chromosome Inversion; Conjugation, Genetic; DNA Transposable Elements; Drug Resistance, Microbial; Enterococcus faecium; Genes, Bacterial; Gram-Positive Bacterial Infections; Lactates; Molecular Sequence Data; Mutagenesis, Insertional; Nucleotidyltransferases; Open Reading Frames; Plasmids; Repetitive Sequences, Nucleic Acid; Replicon; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Transposases; Vancomycin

1993
Gain of D-alanyl-D-lactate or D-lactyl-D-alanine synthetase activities in three active-site mutants of the Escherichia coli D-alanyl-D-alanine ligase B.
    Biochemistry, 1996, Aug-13, Volume: 35, Issue:32

    Topics: Alanine; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Carbon-Oxygen Ligases; Drug Resistance; Escherichia coli; Hydrogen-Ion Concentration; Lactates; Ligases; Mutation; Peptide Synthases; Substrate Specificity; Vancomycin

1996
Effects of the lantibiotic mersacidin on the morphology of staphylococci.
    Zentralblatt fur Bakteriologie : international journal of medical microbiology, 1996, Volume: 284, Issue:2-3

    Topics: Alanine; Anti-Bacterial Agents; Bacteriocins; Penicillins; Peptides; Staphylococcus; Sulfides; Tunicamycin; Vancomycin

1996
D-Alanyl-D-lactate and D-alanyl-D-alanine synthesis by D-alanyl-D-alanine ligase from vancomycin-resistant Leuconostoc mesenteroides. Effects of a phenylalanine 261 to tyrosine mutation.
    The Journal of biological chemistry, 1997, Apr-04, Volume: 272, Issue:14

    Topics: Alanine; Amino Acid Sequence; Binding Sites; Dipeptides; Drug Resistance, Microbial; Lactates; Leuconostoc; Models, Molecular; Molecular Sequence Data; Peptide Synthases; Phenotype; Phenylalanine; Point Mutation; Sequence Alignment; Tyrosine; Vancomycin

1997
Antimicrobial susceptibility testing of a clinical isolate of vancomycin-dependent enterococcus using D-alanine-D-alanine as a growth supplement.
    American journal of clinical pathology, 1998, Volume: 109, Issue:4

    Topics: Alanine; Anti-Bacterial Agents; Drug Resistance, Microbial; Electrophoresis, Gel, Pulsed-Field; Enterococcus; Humans; Microbial Sensitivity Tests; Vancomycin

1998
A trivalent system from vancomycin.D-ala-D-Ala with higher affinity than avidin.biotin.
    Science (New York, N.Y.), 1998, May-01, Volume: 280, Issue:5364

    Topics: Alanine; Avidin; Biotin; Calorimetry; Chromatography, High Pressure Liquid; Dipeptides; Kinetics; Ligands; Thermodynamics; Vancomycin

1998
The structure of VanX reveals a novel amino-dipeptidase involved in mediating transposon-based vancomycin resistance.
    Molecular cell, 1998, Volume: 2, Issue:1

    Topics: Alanine; Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Carboxypeptidases; Copper; Crystallography, X-Ray; Dipeptidases; Dipeptides; DNA Transposable Elements; Drug Resistance, Microbial; Enterococcus faecium; Enzyme Inhibitors; Hedgehog Proteins; Mice; Models, Molecular; Molecular Sequence Data; Organophosphorus Compounds; Propionates; Protein Conformation; Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine-Type D-Ala-D-Ala Carboxypeptidase; Structure-Activity Relationship; Trans-Activators; Vancomycin

1998
A rational strategy for enhancing the affinity of vancomycin towards depsipeptide ligands.
    Bioorganic & medicinal chemistry, 1998, Volume: 6, Issue:7

    Topics: Alanine; Anti-Bacterial Agents; Dipeptides; Drug Resistance, Microbial; Lactic Acid; Ligands; Models, Molecular; Thermodynamics; Vancomycin

1998
Determinants for differential effects on D-Ala-D-lactate vs D-Ala-D-Ala formation by the VanA ligase from vancomycin-resistant enterococci.
    Biochemistry, 1999, Oct-19, Volume: 38, Issue:42

    Topics: Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Arginine; Bacterial Proteins; Base Sequence; Carbon-Oxygen Ligases; Dipeptides; Enterococcus; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Lactic Acid; Leuconostoc; Ligands; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Synthases; Stereoisomerism; Templates, Genetic; Vancomycin; Vancomycin Resistance

1999
[Two cases of methicillin-resistant Staphylococcus aureus (MRSA) sepsis following craniotomy].
    No shinkei geka. Neurological surgery, 2000, Volume: 28, Issue:5

    Topics: Adult; Aged; Alanine; Aminoglycosides; Ampicillin; Anti-Bacterial Agents; Craniotomy; Dibekacin; Drug Therapy, Combination; Female; Humans; Male; Meningeal Neoplasms; Meningioma; Methicillin Resistance; Postoperative Complications; Sepsis; Staphylococcal Infections; Sulbactam; Thienamycins; Treatment Outcome; Vancomycin

2000
Complexation of a peptidocalix[4]arene, a vancomycin mimic, with alanine-containing guests by NMR diffusion measurements.
    The Journal of organic chemistry, 2000, Aug-11, Volume: 65, Issue:16

    Topics: Alanine; Diffusion; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Mimicry; Vancomycin

2000
The D-alanine residues of Staphylococcus aureus teichoic acids alter the susceptibility to vancomycin and the activity of autolytic enzymes.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:10

    Topics: Alanine; Anti-Bacterial Agents; Autolysis; Cell Wall; Lysostaphin; Mutation; Phosphates; Staphylococcus aureus; Teichoic Acids; Vancomycin; Vancomycin Resistance

2000
Binding of vancomycin group antibiotics to D-alanine and D-lactate presenting self-assembled monolayers.
    Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:11

    Topics: Alanine; Anti-Bacterial Agents; Binding Sites; Dimerization; Fatty Acids; Hydrogen Bonding; Kinetics; Lactic Acid; Peptides; Peptidoglycan; Phosphatidylcholines; Protein Binding; Surface Plasmon Resonance; Vancomycin

2000
Fluorescent coupled enzyme assays for D-alanine: application to penicillin-binding protein and vancomycin activity assays.
    Analytical biochemistry, 2000, Dec-15, Volume: 287, Issue:2

    Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Carrier Proteins; Fluorescent Dyes; Hexosyltransferases; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Peptidyl Transferases; Reference Standards; Sensitivity and Specificity; Vancomycin

2000
Selective cleavage of D-Ala-D-Lac by small molecules: re-sensitizing resistant bacteria to vancomycin.
    Science (New York, N.Y.), 2001, Aug-24, Volume: 293, Issue:5534

    Topics: Alanine; Anti-Bacterial Agents; Catalysis; Combinatorial Chemistry Techniques; Computer Simulation; Drug Design; Drug Synergism; Enterococcus; Enterococcus faecalis; Enterococcus faecium; Hydrolysis; Lactates; Methylurea Compounds; Microbial Sensitivity Tests; Models, Molecular; Oligopeptides; Peptide Library; Peptidoglycan; Protein Precursors; Pyrrolidines; Stereoisomerism; Vancomycin; Vancomycin Resistance

2001
Displacement study on a vancomycin-based stationary phase using N-acetyl-D-alanine as a competing agent.
    Journal of chromatographic science, 2002, Volume: 40, Issue:2

    Topics: Alanine; Anti-Bacterial Agents; Binding, Competitive; Chromatography, Affinity; Stereoisomerism; Vancomycin

2002
The role of configurational entropy in biochemical cooperativity.
    Journal of the American Chemical Society, 2002, Apr-10, Volume: 124, Issue:14

    Topics: Alanine; Anti-Bacterial Agents; Computer Simulation; Dimerization; Ligands; Molecular Conformation; Thermodynamics; Vancomycin

2002
Rotational-echo double resonance characterization of the effects of vancomycin on cell wall synthesis in Staphylococcus aureus.
    Biochemistry, 2002, Oct-29, Volume: 41, Issue:43

    Topics: Alanine; Carbon Isotopes; Cell Wall; Cross-Linking Reagents; Glycine; Lysine; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Peptidoglycan; Staphylococcus aureus; Vancomycin

2002
REDOR with a relative full-echo reference.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 2003, Volume: 163, Issue:1

    Topics: Alanine; Anti-Bacterial Agents; Binding Sites; Cell Membrane; Computer Simulation; Deuterium; Isotope Labeling; Membrane Proteins; Models, Biological; Models, Chemical; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Spin Labels; Staphylococcus aureus; Vancomycin

2003
D-Ala-D-lac binding is not required for the high activity of vancomycin dimers against vancomycin resistant enterococci.
    Journal of the American Chemical Society, 2003, Jul-23, Volume: 125, Issue:29

    Topics: Alanine; Anti-Bacterial Agents; Binding Sites; Dimerization; Enterococcus faecalis; Kinetics; Oligopeptides; Spectrometry, Fluorescence; Vancomycin; Vancomycin Resistance

2003
EFFECT OF VANCOMYCIN ON BACILLUS SUBTILIS.
    Archives of biochemistry and biophysics, 1964, Volume: 105

    Topics: Alanine; Antimetabolites; Bacillus subtilis; Bacterial Proteins; Bacteriolysis; Carbon Isotopes; Colorimetry; Glucose; Glutamates; Magnesium; Mucoproteins; Pentosephosphates; Peptides; Pharmacology; Proteins; Research; Spectrophotometry; Uracil; Vancomycin

1964
RESPONSE OF 1-ASPARTIC-4-CARBOXYLASE TO SELECTED INHIBITORS.
    Canadian journal of microbiology, 1964, Volume: 10

    Topics: Alanine; Aspartic Acid; Carbon Dioxide; Carboxy-Lyases; Enzyme Inhibitors; Flavobacterium; Keto Acids; Ketoglutaric Acids; Mitomycin; Mitomycins; Penicillins; Proteins; Pyridoxal Phosphate; Pyruvates; Research; Serine; Vancomycin

1964
RELATIONSHIP OF A BETA-ALANINE-PYRUVIC AMINOTRANSFERASE TO REVERSAL OF D-SERINE INHIBITION OF GROWTH.
    Journal of bacteriology, 1964, Volume: 88

    Topics: Alanine; Alanine Transaminase; Aspartic Acid; beta-Alanine; Cycloserine; Flavobacterium; Ketoglutaric Acids; Mitomycin; Mitomycins; Pantothenic Acid; Penicillins; Pharmacology; Pyridoxal Phosphate; Pyruvates; Research; Serine; Transaminases; Vancomycin

1964
First principles investigation of vancomycin and teicoplanin binding to bacterial cell wall termini.
    Journal of the American Chemical Society, 2004, Jul-14, Volume: 126, Issue:27

    Topics: Alanine; Anti-Bacterial Agents; Bacteria; Cell Wall; Dipeptides; Kinetics; Lactates; Teicoplanin; Thermodynamics; Vancomycin

2004
Inhibition of the D-alanine:D-alanyl carrier protein ligase from Bacillus subtilis increases the bacterium's susceptibility to antibiotics that target the cell wall.
    The FEBS journal, 2005, Volume: 272, Issue:12

    Topics: Adenosine; Alanine; Anti-Bacterial Agents; Bacillus subtilis; Bacterial Proteins; Base Sequence; Carbon-Oxygen Ligases; Carrier Proteins; Cell Wall; Cloning, Molecular; Drug Resistance, Bacterial; Enzyme Inhibitors; Escherichia coli Proteins; Growth Inhibitors; Microbial Sensitivity Tests; Molecular Sequence Data; Protein Processing, Post-Translational; Substrate Specificity; Transferases; Transferases (Other Substituted Phosphate Groups); Vancomycin

2005
Enterococcus gallinarum N04-0414 harbors a VanD-type vancomycin resistance operon and does not contain a D-alanine:D-alanine 2 (ddl2) gene.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:3

    Topics: Alanine; Amino Acid Sequence; Base Sequence; Enterococcus; Genes, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Data; Multigene Family; Operon; Vancomycin; Vancomycin Resistance

2006
Total synthesis and evaluation of [Psi[CH2NH]Tpg4]vancomycin aglycon: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding.
    Journal of the American Chemical Society, 2006, Mar-08, Volume: 128, Issue:9

    Topics: Alanine; Dipeptides; Kinetics; Lactates; Oligopeptides; Vancomycin

2006
Structures of Staphylococcus aureus cell-wall complexes with vancomycin, eremomycin, and chloroeremomycin derivatives by 13C{19F} and 15N{19F} rotational-echo double resonance.
    Biochemistry, 2006, Apr-25, Volume: 45, Issue:16

    Topics: Alanine; Carbon Isotopes; Cell Wall; Glycine; Glycopeptides; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Nitrogen Isotopes; Peptidoglycan; Staphylococcus aureus; Vancomycin

2006
Quantitative measurements of vancomycin binding to self-assembled peptide monolayers on chips by quartz crystal microbalance.
    Analytical biochemistry, 2007, Dec-01, Volume: 371, Issue:1

    Topics: Alanine; Anti-Bacterial Agents; Biosensing Techniques; Crystallization; Equipment Design; Kinetics; Ligands; Models, Molecular; Peptides; Protein Binding; Quartz; Sensitivity and Specificity; Surface Plasmon Resonance; Vancomycin

2007
Increased D-alanylation of lipoteichoic acid and a thickened septum are main determinants in the nisin resistance mechanism of Lactococcus lactis.
    Microbiology (Reading, England), 2008, Volume: 154, Issue:Pt 6

    Topics: Alanine; Anti-Bacterial Agents; Cell Division; Cell Wall; Drug Resistance, Bacterial; Lactococcus lactis; Lipopolysaccharides; Microscopy, Confocal; Microscopy, Electron; Nisin; Teichoic Acids; Vancomycin

2008
Crystalline degradation products of vancomycin as chiral stationary phase in microcolumn liquid chromatography.
    Journal of separation science, 2008, Volume: 31, Issue:13

    Topics: Alanine; Atropine; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Liquid; Crystallization; Methyldopa; Microchemistry; Particle Size; Phenylalanine; Propranolol; Silicon Dioxide; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Vancomycin

2008
A liquid chromatography-tandem mass spectrometry assay for d-Ala-d-Lac: a key intermediate for vancomycin resistance in vancomycin-resistant enterococci.
    Analytical biochemistry, 2013, Nov-15, Volume: 442, Issue:2

    Topics: Alanine; Chromatography, Liquid; Enterococcus; Humans; Lactates; Linear Models; Tandem Mass Spectrometry; Vancomycin; Vancomycin Resistance

2013
Structural basis for the evolution of vancomycin resistance D,D-peptidases.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Apr-22, Volume: 111, Issue:16

    Topics: Alanine; Binding Sites; DNA Mutational Analysis; Evolution, Molecular; Ligands; Models, Molecular; Mutagenesis; Serine-Type D-Ala-D-Ala Carboxypeptidase; Substrate Specificity; Vancomycin; Vancomycin Resistance

2014
Total synthesis of [Ψ[C(═NH)NH]Tpg(4)]vancomycin and its (4-chlorobiphenyl)methyl derivative: impact of peripheral modifications on vancomycin analogues redesigned for dual D-Ala-D-Ala and D-Ala-D-Lac binding.
    Journal of the American Chemical Society, 2014, Oct-01, Volume: 136, Issue:39

    Topics: Alanine; Binding Sites; Dipeptides; Lactates; Molecular Conformation; Stereoisomerism; Vancomycin

2014
Allosteric signalling in the outer membrane translocation domain of PapC usher.
    eLife, 2014, Oct-28, Volume: 3

    Topics: Alanine; Allosteric Regulation; Amino Acid Motifs; Amino Acid Substitution; Anti-Bacterial Agents; Cell Membrane Permeability; Erythromycin; Escherichia coli Proteins; Fimbriae, Bacterial; Gene Expression; Membrane Potentials; Molecular Dynamics Simulation; Molecular Sequence Data; Mutation; Porins; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Protein Transport; Signal Transduction; Uropathogenic Escherichia coli; Vancomycin

2014
Determination of Noncovalent Binding Using a Continuous Stirred Tank Reactor as a Flow Injection Device Coupled to Electrospray Ionization Mass Spectrometry.
    Journal of the American Society for Mass Spectrometry, 2015, Volume: 26, Issue:7

    Topics: Alanine; Drug Discovery; Equipment Design; Flow Injection Analysis; Models, Chemical; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Vancomycin

2015
The functional dlt operon of Clostridium butyricum controls the D-alanylation of cell wall components and influences cell septation and vancomycin-induced lysis.
    Anaerobe, 2015, Volume: 35, Issue:Pt B

    Topics: Alanine; Anti-Bacterial Agents; Bacteriolysis; Cell Division; Cell Wall; Clostridium butyricum; Microscopy; Operon; Surface Properties; Teichoic Acids; Vancomycin

2015
Substrate Inhibition of VanA by d-Alanine Reduces Vancomycin Resistance in a VanX-Dependent Manner.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8

    Topics: Alanine; Anti-Bacterial Agents; Bacterial Proteins; Carbon-Oxygen Ligases; Cell Wall; Drug Resistance, Microbial; Enterococcus faecium; Glycopeptides; Ligases; Peptidoglycan; Serine-Type D-Ala-D-Ala Carboxypeptidase; Streptomyces coelicolor; Vancomycin; Vancomycin Resistance

2016
Quantification of the d-Ala-d-Lac-Terminated Peptidoglycan Structure in Vancomycin-Resistant Enterococcus faecalis Using a Combined Solid-State Nuclear Magnetic Resonance and Mass Spectrometry Analysis.
    Biochemistry, 2017, 01-31, Volume: 56, Issue:4

    Topics: Alanine; Anti-Bacterial Agents; Cell Wall; Dipeptides; Endopeptidases; Enterococcus faecalis; Lactates; Magnetic Resonance Spectroscopy; Mass Spectrometry; Peptidoglycan; Uridine Diphosphate N-Acetylmuramic Acid; Vancomycin; Vancomycin Resistance

2017
Hidden Mode of Action of Glycopeptide Antibiotics: Inhibition of Wall Teichoic Acid Biosynthesis.
    The journal of physical chemistry. B, 2017, 04-27, Volume: 121, Issue:16

    Topics: Alanine; Anti-Bacterial Agents; Biosynthetic Pathways; Cell Wall; Glycopeptides; Humans; Lipoglycopeptides; Staphylococcal Infections; Staphylococcus aureus; Teichoic Acids; Vancomycin

2017
Effect of the additional cysteine 503 of vancomycin-resistant Enterococcus faecalis (V583) alkylhydroperoxide reductase subunit F (AhpF) and the mechanism of AhpF and subunit C assembling.
    Free radical biology & medicine, 2019, Volume: 138

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Bacterial Proteins; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Enterococcus faecalis; Escherichia coli; Gene Expression; Kinetics; Molecular Docking Simulation; Mutagenesis, Site-Directed; Peroxiredoxins; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Subunits; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Vancomycin; Vancomycin Resistance

2019
A Biochemical Lanthanide-Encoding Approach Enables Quantitative Monitoring of the Bacterial Response to Vancomycin Treatment.
    Biochemistry, 2020, 09-29, Volume: 59, Issue:38

    Topics: Alanine; Anti-Bacterial Agents; Europium; Gadolinium; Isotope Labeling; Lanthanoid Series Elements; Leucine; Methionine; Microbial Viability; Peptidoglycan; Samarium; Staphylococcus aureus; Stereoisomerism; Uridine Diphosphate N-Acetylmuramic Acid; Vancomycin

2020
Reversible dougong structured receptor-ligand recognition for building dynamic extracellular matrix mimics.
    Proceedings of the National Academy of Sciences of the United States of America, 2022, 02-22, Volume: 119, Issue:8

    Topics: Alanine; Biocompatible Materials; Biomimetics; Dipeptides; Extracellular Matrix; Humans; Hydrogels; Ligands; Protein Engineering; Vancomycin

2022
Divergent Effects of Peptidoglycan Carboxypeptidase DacA on Intrinsic β-Lactam and Vancomycin Resistance.
    Microbiology spectrum, 2022, 08-31, Volume: 10, Issue:4

    Topics: Alanine; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Carboxypeptidases; Escherichia coli; Peptidoglycan; Vancomycin; Vancomycin Resistance

2022