alanine and uracil

alanine has been researched along with uracil in 108 studies

Research

Studies (108)

Timeframe	Studies, this research(%)	All Research%
pre-1990	57 (52.78)	18.7374
1990's	12 (11.11)	18.2507
2000's	32 (29.63)	29.6817
2010's	5 (4.63)	24.3611
2020's	2 (1.85)	2.80

Authors

Authors	Studies
Grossfeld, RM	1
Durham, NN; Walker, CA	1
Kiyomiya, A; Koyama, N; Noso, Y; Ota, K	1
Bhanot, OS; Chambers, RW	1
Chittenden, GJ; Schwartz, AW	2
Dahnke, HG; Mosebach, KO	1
Jane, DE; Mayer, ML; Patneau, DK; Watkins, JC	1
Clifford, DB; Thio, LL; Zorumski, CF	1
Berger, R; Beukenhorst, H; de Bree, PK; Dorland, L; Duran, M; Rovers, P; Schreuder, CH	1
Pu, WT; Struhl, K	1
Engelbrecht, C; Yngner, T	1
Furusawa, M; Hara, Y; Kono, A	1
Fujimoto, S; Kaneko, M; Kikugawa, M; Mizota, C; Tamaki, N	1
O'Donovan, GA; Shanley, MS; Traut, TW; West, TP	1
Tamiya, H	1
Lambein, F; van Parijs, R	2
Garrick-Silversmith, L; Torriani, A	1
Bĕhal, V; Hostálek, Z; Lynen, F; Podojil, M; Vanĕk, Z	1
Stroman, P	1
Gilvarg, C; Levin, Y	1
Harshman, RB; Yamazaki, H	2
Rothwell, JD; Yamazaki, H	1
Böck, A; Buckel, P; Piepersberg, W; Ruffler, D	1
Ashworth, TS; Brown, EG; Roberts, FM	1
Kuzina, ZA; Tereshin, IM	1
Pine, MJ	1
Friedman, H; Lu, P; Rich, A	1
Khan, SR; Yamazaki, H	1
Camakaris, J; Cotton, RG; Danks, DM	1
Ikeda, Y; Sakakibara, Y	1
Bobikov, EV; Sazykin, IuO	1
Kaltwasser, H; Krämer, J	1
Apirion, D; Mangiarotti, G; Schlessinger, D; Silengo, L	1
Knutsen, G	1
Becroft, DM; Phillips, LI; Simmonds, A	1
Jones, ME; Prescott, LM	1
Aonuma, S; Hama, T; Okumura, H; Tamaki, N	1
Daniel, JC; Gulyas, BJ	1
Fitzgerald, T; Yotis, WW	1
Lembein, F; Van Parijs, R	1
Jacobs, ME	1
Kallenbach, NR	1
Brown, EG; Mangat, BS	1
Herrmann, RL; White, CW	1
Kendrick-Jones, J; Perry, SV	1
Magrath, DI; Shaw, DC	1
Adman, R; Doty, P	1
Cronan, JE	1
O'Donovan, GA; Shanley, MS; West, TP	1
Jane, DE; Mayer, ML; Watkins, JC; Wong, LA	1
Beaver, KM; Hawkins, LM; Jane, DE; Roberts, PJ; Sunter, DC; Taylor, PM	1
Bowie, D; Smart, TG	1
Imaoka, T; Kawaguchi, T; Kishi, K; Kiyono, K; Kubo, M; Tatsumi, K; Yamauchi, T; Yanagihara, Y	1
Fujimoto, S; Kaneko, M; Kikugawa, M; Kontani, Y; Tamaki, N	1
Harada, M; Kimura, A; Koga, K; Miura, I; Nishitani, H	1
Beart, PM; Ganakas, AM; Lawrence, AJ; Lunn, ML; Mercer, LD	1
Bleakman, D; Deverill, M; Hoo, K; Jane, DE; Kamboj, R; Mandelzys, A	1
Edwards, AM; Friesen, JD; Goryachev, A; Hemming, SA; Jansma, DB; Macgregor, PF	1
Arai, AC; Kessler, M; Lynch, G; Rogers, G	1
Eisenstein, M; Hollmann, M; Kizelsztein, P; Strutz, N; Teichberg, VI	1
Dohovics, R; Hermann, A; Janáky, R; Oja, SS; Saransaari, P; Varga, V	1
Bhagwat, AS; Sharath, AN; Weinhold, E	1
Fletcher, JM; Harbord, MG; Harrison, RJ; Poplawski, NK; Wiltshire, EJ	1
Fukushima, T; Marshall, J; Sakata, K; Shingai, R	1
Buck, CJ; Mueller, EG; Palenchar, PM	1
Dong, S; Wu, G	1
Kise, KJ; Shin, JA	1
Jane, DE; More, JC; Troop, HM	1
Dolman, NP; Jane, DE; More, JC; Troop, HM	1
Gouaux, E; Jin, R	1
Banke, TG; Gouaux, E; Jin, R; Mayer, ML; Traynelis, SF	1
Fukushima, T; Ichinose, M; Ogurusu, T; Shingai, R	1
FINK, K; FINK, RM; HENDERSON, RB	1
GRISOLIA, S; WALLACH, DP	1
FRITZSON, P	1
FRITZSON, P; PIHL, A	1
GMELIN, R	1
BELJANSKI, M; FISCHER, C	1
BEST, GK; DURHAM, NN	1
COHEN, PP; LINDSAY, RH; NAKAGAWA, H	1
HASH, JH; MILLER, PA; WISHNICK, M	1
Bowen, KH; Dabkowska, I; Gutowski, M; Nilles, JM; Rak, J; Stokes, ST	1
Alt, A; Bleakman, D; Bortolotto, ZA; Collingridge, GL; Dolman, NP; Jack, S; Jane, DE; Knauss, JL; More, JC; Morley, RM; Nistico, R; Roberts, PJ; Troop, HM	1
Alt, A; Bleakman, D; Collingridge, GL; Dolman, NP; Jane, DE; Knauss, JL; More, JC; Troop, HM	1
Allan, RD; Greenwood, JR; Martín, BO; Mewett, KN; Pickering, DS	1
Carmeliet, P; Fontaine, RH; Gallego, J; Gressens, P; Hicklin, DJ; Laudenbach, V; Leroux, P; Marret, S; Medja, F	1
Clarke, VR; Collingridge, GL; Dolman, NP; Huxter, JR; Jane, DE; More, JC; Muller, RU; Roloff, Ev; Zinyuk, LE	1
Alt, A; Bleakman, D; Collingridge, GL; Dolman, NP; Glasser, CR; Jane, DE; Knauss, JL; Mayer, ML; More, JC; Pentikäinen, OT	1
Chae, KA; Cho, HJ; Kim, JS; Lee, H; Seo, DC; Shin, HC; Sung, JM	1
Jayaraman, V; Mankiewicz, KA; Rambhadran, A; Wathen, L	1
Fenwick, MK; Oswald, RE	1
Destro, R; Larsen, S; Madsen, AØ; Munshi, P; Spackman, MA	1
Alushin, GM; Bleakman, D; Bortolotto, ZA; Clarke, VR; Collingridge, GL; Dargan, SL; Doherty, AJ; Fitzjohn, SM; Jane, DE; Lodge, D; Mayer, ML; Nisticò, R; Ogden, AM; Sherwood, JL	1
Ahmed, AH; Fenwick, MK; Jane, DE; Maltsev, AS; Oswald, RE	1
del Aguila, MA; Fernández de la Pradilla, R; Lwoff, N; Tortosa, M; Viso, A	1
Ahmed, AH; Fenwick, MK; Jane, DE; Loh, AP; Oswald, RE; Romero, B; Sondermann, H; Thompson, MD	1
Duncan, GE; Koller, BH; Moy, SS	1
Cooper, D; Jayaraman, V; Landes, CF; MacLean, DM; Poddar, N; Ramaswamy, S; Rambhadran, A; Taylor, JN; Uhm, H	1
Ahmed, AH; Loh, AP; Martinez, M; Oswald, RE	1
Albuquerque, EL; Bezerra, EM; Caetano, EW; Corso, G; da Costa, RF; Freire, VN; Fulco, UL; Lima Neto, JX	1
Tobi, D	1
Bretner, M; Grześkowiak, P; Ignatowska, J; Karatsai, O; Koszytkowska-Stawińska, M; Mironiuk-Puchalska, E; Rędowicz, MJ; Wielechowska, M; Wińska, P	1
Borthakur, D; Negi, VS; Pal, A	1
Duffy, EM; Jorgensen, WL	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1

Reviews

1 review(s) available for alanine and uracil

Article	Year
Biochemistry of plants N-heterocyclic non-protein amino acids. Amino acids, 2021, Volume: 53, Issue:6 Topics: Alanine; Amino Acids, Diamino; Plants; Uracil	2021

Other Studies

107 other study(ies) available for alanine and uracil

Article	Year
The metabolism of beta-alanine by lobster nervous tissue in vitro. Comparative biochemistry and physiology. C: Comparative pharmacology, 1976, Volume: 53, Issue:1 Topics: Alanine; Animals; Aspartic Acid; gamma-Aminobutyric Acid; Ganglia; Isomerism; Nephropidae; Nerve Tissue Proteins; Protein Biosynthesis; RNA; Transcription, Genetic; Uracil	1976
Effect of carbon source during growth on sensitivity of Pseudomonas fluorescens to actinomycin D. Canadian journal of microbiology, 1975, Volume: 21, Issue:1 Topics: Alanine; Barbiturates; Binding Sites; Carbon Radioisotopes; Cell Wall; Dactinomycin; Drug Resistance, Microbial; Edetic Acid; Glucose; Lipopolysaccharides; Phenylalanine; Polysaccharides, Bacterial; Pseudomonas fluorescens; Succinates; Uracil	1975
The basis of the alkalophilic property of a species of bacillus. Journal of general microbiology, 1975, Volume: 86, Issue:2 Topics: Adenosine Triphosphatases; Alanine; Amino Acid Oxidoreductases; Amino Acids; Aminoisobutyric Acids; Bacillus; Bacterial Proteins; Carbon Radioisotopes; Cell Membrane; Glucose; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Malate Dehydrogenase; NAD; Oxygen Consumption; Protoplasts; RNA, Bacterial; Species Specificity; Uracil	1975
Bisulfite-induced C changed to U transitions in yeast alanine tRNA. The Journal of biological chemistry, 1977, Apr-25, Volume: 252, Issue:8 Topics: Alanine; Anticodon; Base Sequence; Cytosine; Kinetics; Oligoribonucleotides; Ribonuclease T1; Ribonucleosides; RNA, Transfer; Saccharomyces cerevisiae; Sulfites; Uracil	1977
Synthesis of uracil and thymine under simulated prebiotic conditions. Bio Systems, 1977, Volume: 9, Issue:2-3 Topics: Acetates; Alanine; Chemical Phenomena; Chemistry; Hot Temperature; Minerals; Photolysis; Propionates; Thymine; Ultraviolet Rays; Uracil; Urea; Water	1977
Possible pathway for prebiotic uracil synthesis by photodehydrogenation. Nature, 1976, Sep-23, Volume: 263, Issue:5575 Topics: Alanine; Photochemistry; Uracil; Urea	1976
[In vivo studies on the metabolism of pyrimidine nucleosides (author's transl)]. Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1975, Volume: 356, Issue:10 Topics: Alanine; Animals; Cytidine; Liver; Male; Pyrimidine Nucleosides; Rats; Thymidine; Time Factors; Uracil; Uridine	1975
Activation and desensitization of AMPA/kainate receptors by novel derivatives of willardiine. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1992, Volume: 12, Issue:2 Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Evoked Potentials; Hippocampus; Ibotenic Acid; Isomerism; Kainic Acid; Kinetics; Mathematics; Mice; Mice, Inbred C57BL; Models, Neurological; Neurons; Pyrimidinones; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Structure-Activity Relationship; Uracil	1992
Effects of bromowillardiine and willardiine on non-N-methyl-D-aspartate receptors in postnatal rat hippocampal neurons. Molecular pharmacology, 1991, Volume: 40, Issue:1 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Alanine; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Hippocampus; Membrane Potentials; Neurons; Pyrimidinones; Quinoxalines; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Uracil	1991
Dihydropyrimidinuria: a new inborn error of pyrimidine metabolism. Journal of inherited metabolic disease, 1991, Volume: 14, Issue:3 Topics: Alanine; Amidohydrolases; Chromatography, High Pressure Liquid; Fibroblasts; Humans; Infant; Liver; Male; Neutrophils; Purine-Pyrimidine Metabolism, Inborn Errors; Spectrophotometry, Ultraviolet; Uracil	1991
Highly conserved residues in the bZIP domain of yeast GCN4 are not essential for DNA binding. Molecular and cellular biology, 1991, Volume: 11, Issue:10 Topics: Alanine; Amino Acid Sequence; Asparagine; Base Sequence; Biological Evolution; DNA Mutational Analysis; DNA-Binding Proteins; DNA, Fungal; Fungal Proteins; Leucine Zippers; Molecular Sequence Data; Oncogene Protein p65(gag-jun); Protein Conformation; Protein Kinases; Recombinant Fusion Proteins; Saccharomyces cerevisiae Proteins; Sequence Alignment; Transcription Factors; Uracil; Yeasts	1991
Metabolism of uridine and determination of liver ribonucleic acid synthesis in developing and adult mice. The International journal of biochemistry, 1985, Volume: 17, Issue:4 Topics: Aging; Alanine; Animals; beta-Alanine; Liver; Male; Mice; Orotic Acid; RNA; Tritium; Uracil; Uridine; Uridine Monophosphate; Uridine Triphosphate	1985
[Effect of uracil on the both reactions, 5-fluorouracil degradation into 2-fluoro-beta-alanine and 5-fluorouracil splitting from tegafur in human tumor]. Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 1 Topics: Adenocarcinoma, Papillary; Alanine; beta-Alanine; Fluorouracil; Humans; Lung Neoplasms; Tegafur; Tumor Cells, Cultured; Uracil	1989
Inhibitory effect of 6-azauracil on beta-alanine metabolism in rat. Journal of nutritional science and vitaminology, 1989, Volume: 35, Issue:5 Topics: Alanine; Amidohydrolases; Animals; Dihydrouracil Dehydrogenase (NAD+); Liver; Male; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Rats; Rats, Inbred Strains; Uracil; Uridine Monophosphate	1989
A Salmonella typhimurium strain defective in uracil catabolism and beta-alanine synthesis. Journal of general microbiology, 1985, Volume: 131, Issue:5 Topics: Alanine; beta-Alanine; Mutation; Salmonella typhimurium; Temperature; Transduction, Genetic; Uracil	1985
Cell differentiation in Chlorella. Symposia of the Society for Experimental Biology, 1963, Volume: 17 Topics: Alanine; Antimetabolites; Azaguanine; Barbiturates; Caffeine; Cell Differentiation; Cell Division; Chloramphenicol; Dihydrostreptomycin Sulfate; Eukaryota; In Vitro Techniques; Microscopy, Electron; Protein Biosynthesis; Sulfates; Thiophenes; Triazines; Uracil	1963
Identification of 1-alanyl-5-ribosyl-4-amino-uracil in pea seedlings ("Pisum sativum"). Archives internationales de physiologie et de biochimie, 1968, Volume: 76, Issue:1 Topics: Alanine; Chemical Phenomena; Chemistry; Chromatography, Paper; Electrophoresis; Hydrogen-Ion Concentration; Ribose; Seeds; Spectrophotometry; Uracil	1968
Alanyluracils in plants. Archives internationales de physiologie et de biochimie, 1969, Volume: 77, Issue:1 Topics: Alanine; Plants; Seeds; Uracil	1969
Macromolecular syntheses during germination and outgrowth of Bacillus subtilis spores. Journal of bacteriology, 1973, Volume: 114, Issue:2 Topics: Alanine; Amino Acids; Bacillus subtilis; Bacterial Proteins; Carbon Isotopes; Culture Media; Glucose; Hydrogen-Ion Concentration; Microscopy, Phase-Contrast; Mutation; RNA, Bacterial; Spores; Spores, Bacterial; Tryptophan; Uracil	1973
Regulation of biosynthesis of excessive metabolites. XVI. Origin of the terminal group of tetracyclines. Folia microbiologica, 1974, Volume: 19, Issue:2 Topics: Acetates; Alanine; Bicarbonates; Carbon Radioisotopes; Colorimetry; Glutamates; Glutarates; Malonates; Propionates; Pyruvates; Streptomyces aureofaciens; Succinates; Tetracycline; Uracil	1974
Pyrimidine-sensitive drosophila wing mutants: withered (whd), tilt (tt) and dumpy (dp). Hereditas, 1974, Volume: 78, Issue:2 Topics: Alanine; Animals; Chromosomes; Culture Media; Drosophila melanogaster; Female; Genes, Lethal; Male; Mutation; Phenotype; Phosphotransferases; Pyrimidines; Suppression, Genetic; Thymidine; Thymine; Uracil; Uridine; Wings, Animal	1974
Response of Escherichia coli to ornithyl peptides. The Journal of biological chemistry, 1972, Jan-25, Volume: 247, Issue:2 Topics: Alanine; Bacterial Proteins; Benzyl Compounds; Carbon Isotopes; Escherichia coli; Formates; Genetics, Microbial; Isoleucine; Lysine; Microbial Sensitivity Tests; Mutation; Nucleic Acids; Ornithine; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Peptides; Uracil	1972
MSI accumulation induced by sodium chloride. Biochemistry, 1972, Feb-15, Volume: 11, Issue:4 Topics: Alanine; Arginine; Bacterial Proteins; Carbon Isotopes; Chloramphenicol; Chromatography, Thin Layer; Culture Media; Drug Stability; Escherichia coli; Genetics, Microbial; Guanine Nucleotides; Hydroxides; Hypertonic Solutions; Kinetics; Mutation; Phosphoric Acids; Phosphorus Isotopes; Potassium; Rifampin; RNA, Bacterial; Sodium Chloride; Thiophenes; Uracil	1972
Limited production of R17 ribonucleic acid phage in the presence of rifampin. Biochemistry, 1972, Aug-29, Volume: 11, Issue:18 Topics: Alanine; Carbon Isotopes; Centrifugation, Density Gradient; Chloramphenicol; Coliphages; Electrophoresis, Disc; Escherichia coli; Kinetics; Rifampin; RNA, Viral; Sodium Dodecyl Sulfate; Uracil; Viral Proteins; Virus Replication	1972
RNA overproducing revertants of an alanyl-tRNA synthetase mutant of Escherichia coli. Molecular & general genetics : MGG, 1972, Volume: 119, Issue:4 Topics: Alanine; Amino Acyl-tRNA Synthetases; Carbon Isotopes; Centrifugation, Zonal; Crosses, Genetic; Escherichia coli; Genes, Regulator; Mutation; RNA, Bacterial; RNA, Ribosomal; RNA, Transfer; Temperature; Transduction, Genetic; Uracil	1972
Biosynthesis of willardiine and isowillardiine in germinating pea seeds and seedlings. The Biochemical journal, 1972, Volume: 129, Issue:4 Topics: Alanine; Carbon Isotopes; Chromatography, Ion Exchange; Light; Orotic Acid; Pyrimidinones; Seeds; Structure-Activity Relationship; Thiouracil; Uracil	1972
[The effect of a series of antibiotics on nucleic acid and protein synthesis in Salmonella pullorum]. Antibiotiki, 1973, Volume: 18, Issue:11 Topics: Alanine; Bacterial Proteins; Carbon Radioisotopes; Chloramphenicol; DNA, Bacterial; Erythromycin; Lysine; RNA, Bacterial; Salmonella; Tetracycline; Thymine; Time Factors; Uracil	1973
Kinetics of maturation of the amino termini of the cell proteins of Escherichia coli. Biochimica et biophysica acta, 1969, Jan-21, Volume: 174, Issue:1 Topics: Alanine; Amino Acids; Bacterial Proteins; Carbon Isotopes; Chloramphenicol; Depression, Chemical; Electrophoresis; Escherichia coli; Genetics, Microbial; Membranes; Methionine; Mutation; Ribosomes; RNA, Bacterial; Solubility; Time Factors; Uracil	1969
An in vivo block in the initiation of protein synthesis. Cold Spring Harbor symposia on quantitative biology, 1969, Volume: 34 Topics: Alanine; Bacterial Proteins; Bacteriolysis; Carbon Isotopes; Centrifugation, Density Gradient; Centrifugation, Zonal; Cold Temperature; Depression, Chemical; Escherichia coli; Ribosomes; Rifampin; RNA; RNA, Messenger; Species Specificity; Time Factors; Uracil	1969
Continued expression of the ribonucleic acid control gene during inhibition of Escherichia coli ribonucleic acid and protein synthesis. Journal of bacteriology, 1970, Volume: 102, Issue:3 Topics: Alanine; Bacterial Proteins; Carbon Isotopes; Chloramphenicol; Coliphages; Depression, Chemical; Escherichia coli; Genes; Genetics, Microbial; Histidine; Isoleucine; Methionine; Ribosomes; Rifampin; RNA, Bacterial; RNA, Viral; Spectrophotometry; Uracil; Viral Proteins	1970
A screening test for urinary purines and pyrimidines and related compounds using auxotrophic mutants of Escherichia coli K12. Biochemical medicine, 1970, Volume: 3, Issue:4 Topics: Adenine; Alanine; Aspartic Acid; Biological Assay; Carbamates; Child; Chromatography, Paper; Cytosine; Escherichia coli; Glycosides; Humans; Imidazoles; Inosine; Mutation; Orotic Acid; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Purinones; Pyrimidines; Ribose; Thymine; Uracil; Uric Acid	1970
Formation of ppGpp in a relaxed and stringent strain of Escherichia coli during diauxie lag. Biochemistry, 1971, Oct-12, Volume: 10, Issue:21 Topics: Alanine; Autoradiography; Bacterial Proteins; Carbon Isotopes; Chromatography, Thin Layer; Escherichia coli; Genetics, Microbial; Glucose; Guanine Nucleotides; Mutation; Phosphates; Phosphorus Isotopes; RNA, Bacterial; Succinates; Thiophenes; Uracil	1971
The dormant spore-specific state of DNA and macromolecular synthesis in spheroplasts of Bacillus subtilis spores. Biochimica et biophysica acta, 1969, Apr-22, Volume: 179, Issue:2 Topics: Adenine; Alanine; Amino Acids; Bacillus subtilis; Calcium; Carbon Isotopes; Culture Media; DNA, Bacterial; Glucose; Hot Temperature; Magnesium; Manganese; Muramidase; Nucleosides; Osmolar Concentration; Protein Biosynthesis; RNA, Bacterial; Spores; Thymidine; Tritium; Uracil	1969
[Effect of desoxystreptamine-containing antibiotics on incorporation of labelled amino acids and precursors of nucleic acids in different fractions of Proteus vulgaris and Pseudomonas aeruginosa]. Antibiotiki, 1969, Volume: 14, Issue:9 Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Aspartic Acid; Bacterial Proteins; Cell Wall; Depression, Chemical; DNA, Bacterial; Erythromycin Ethylsuccinate; Gentamicins; Glycine; Kanamycin; Leucine; Lysine; Methionine; Neomycin; Proteus; Pseudomonas aeruginosa; RNA, Bacterial; Thymine; Time Factors; Tyrosine; Uracil	1969
[Utilization of pyrimidine derivatives by Hydrogenomonas facilis. I. Intermediates and enzymes of cytosine degradation]. Archiv fur Mikrobiologie, 1969, Volume: 68, Issue:3 Topics: Alanine; Amidohydrolases; Aminohydrolases; Chemical Phenomena; Chemistry; Chromatography, Paper; Culture Media; Cytosine; Hydro-Lyases; Oxidoreductases; Propionates; Pseudomonas; Uracil; Urea; Urease	1969
Biosynthetic precursors of 30S and 50S ribosomal particles in Escherichia coli. Biochemistry, 1968, Volume: 7, Issue:1 Topics: Alanine; Bacillus subtilis; Bacterial Proteins; Carbon Isotopes; Centrifugation, Zonal; Chromatography, Ion Exchange; Escherichia coli; Hybridization, Genetic; Kinetics; Nucleic Acid Denaturation; Phenols; Ribonucleases; Ribosomes; RNA, Bacterial; Solubility; Tritium; Uracil	1968
Degradation of uracil by synchronous cultures of Chlorella fusca. Biochimica et biophysica acta, 1972, May-29, Volume: 269, Issue:3 Topics: Alanine; Biological Transport; Carbon Dioxide; Carbon Isotopes; Cells, Cultured; Chlorella; Chlorophyta; Chromatography, Thin Layer; Glucose; Kinetics; Light; Mathematics; Nucleic Acids; Oxygen Consumption; Propionates; Radiation Effects; Tritium; Uracil; Urea	1972
Hereditary orotic aciduria: long-term therapy with uridine and a trial of uracil. The Journal of pediatrics, 1969, Volume: 75, Issue:5 Topics: Alanine; Anemia, Macrocytic; Child; Child, Preschool; Humans; Infant; Intellectual Disability; Male; Orotic Acid; Purine-Pyrimidine Metabolism, Inborn Errors; Uracil; Uridine	1969
Modified methods for the determination of carbamyl aspartate. Analytical biochemistry, 1969, Volume: 32, Issue:3 Topics: Alanine; Antipyrine; Arginine; Aspartic Acid; Carbamates; Citrulline; Colorimetry; Darkness; Indicators and Reagents; Methods; Oximes; Spectrophotometry; Sulfuric Acids; Time Factors; Uracil; Urea	1969
Orotate as a beta-alanine donor for anserine and carnosine biosynthesis, and effects of actinomycin D and azauracil on their pathway. Journal of biochemistry, 1969, Volume: 66, Issue:2 Topics: Alanine; Amino Acids; Animals; Autoanalysis; Autoradiography; Body Weight; Carbon Isotopes; Chromatography, Paper; Dactinomycin; Depression, Chemical; Dipeptides; Injections, Intramuscular; Injections, Intraperitoneal; Injections, Intravenous; Liver; Male; Muscle Proteins; Muscles; Orotic Acid; Rats; RNA; Skeleton; Stimulation, Chemical; Temperature; Time Factors; Triazines; Uracil	1969
Incorporation of labeled nucleic acid and protein precursors by diapausing and nondiapausing blastocysts. Biology of reproduction, 1969, Volume: 1, Issue:1 Topics: Alanine; Animals; Autoradiography; Caniformia; Carbon Isotopes; Dactinomycin; DNA; Embryo Implantation; Female; In Vitro Techniques; Lactation; Mink; Morphogenesis; Ovum; Pregnancy; Protein Biosynthesis; Puromycin; Rabbits; Rats; RNA; RNA, Messenger; Thymine; Uracil; Urease; Valine; Xenarthra	1969
Interference with cellular incorporation of substrates into Staphylococcus aureus by hormones. Journal of medical microbiology, 1971, Volume: 4, Issue:1 Topics: Acetates; Adenine; Alanine; Amino Acids; Androsterone; Carbon Isotopes; Dihydrotestosterone; Glucose; Glutamates; Glycerol; Gonadal Steroid Hormones; Hydroxyprogesterones; Lysine; Progesterone; Staphylococcus; Uracil	1971
Isolation and characterization of 1-ananyl-uracil (willardiine) and 3-alanyl-uracil (iso-willardiine) from Pisum sativum. Biochemical and biophysical research communications, 1968, Aug-13, Volume: 32, Issue:3 Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Crystallization; Hydrogen-Ion Concentration; Plants; Spectrophotometry; Uracil	1968
Beta-alanine used by ebony and normal drosophila melanogaster with notes on glucose, uracil, dopa, and dopamine. Biochemical genetics, 1968, Volume: 1, Issue:3 Topics: Alanine; Animals; Behavior, Animal; Biological Transport; Carbon Isotopes; Cyanides; Dihydroxyphenylalanine; Dopamine; Drosophila; Ethanol; Female; Glucose; Heterozygote; Hexosephosphates; Mutation; Ovary; Permeability; Tritium; Uracil	1968
Theory of thermal transitions in low molecular weight RNA chains. Journal of molecular biology, 1968, Nov-14, Volume: 37, Issue:3 Topics: Adenine; Alanine; Chemical Phenomena; Chemistry, Physical; Cytosine; Guanine; Models, Structural; Molecular Weight; RNA; Thermodynamics; Tyrosine; Uracil	1968
Structure of a pyrimidine amino acid from pea seedlings. Biochimica et biophysica acta, 1969, May-06, Volume: 177, Issue:3 Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry; Crystallization; Electrophoresis; Esters; Infrared Rays; Magnetic Resonance Spectroscopy; Plants; Pyrimidines; Spectrum Analysis; Ultraviolet Rays; Uracil	1969
Beta-alanine inhibition in Neurospora and its reversal by carbamyl compounds. Biochimica et biophysica acta, 1966, Aug-24, Volume: 124, Issue:2 Topics: Alanine; Aminobutyrates; Arginine; Asparagine; Carbamates; Citrulline; Molecular Biology; Mutation; Neurospora; Nucleosides; Uracil	1966
Protein synthesis and enzyme response to contractile activity in skeletal muscle. Nature, 1967, Jan-28, Volume: 213, Issue:5074 Topics: Alanine; Animals; Anura; Azaguanine; Carbon Isotopes; Creatine Kinase; Dactinomycin; Ethionine; Leucine; Muscle Contraction; Muscles; Puromycin; Uracil	1967
The occurrence and source of beta-alanine in alkaline hydrolysates of sRNA: a sensitive method for the detection and assay of 5,6-dihydrouracil residues in RNA. Biochemical and biophysical research communications, 1967, Jan-10, Volume: 26, Issue:1 Topics: Alanine; Alkalies; Autoanalysis; Chemical Phenomena; Chemistry; Chromatography, Paper; Electrophoresis; Magnetic Resonance Spectroscopy; RNA, Transfer; Uracil; Yeasts	1967
Inactivation of alanine acceptance activity of yeast transfer RNA by photochemical reduction of uracil. Biochemical and biophysical research communications, 1967, Jun-09, Volume: 27, Issue:5 Topics: Adenine Nucleotides; Alanine; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Cytosine Nucleotides; Guanine Nucleotides; Light; RNA, Transfer; Tritium; Uracil; Uracil Nucleotides; Yeasts	1967
Beta-alanine synthesis in Escherichia coli. Journal of bacteriology, 1980, Volume: 141, Issue:3 Topics: Alanine; Aspartic Acid; beta-Alanine; Carboxy-Lyases; Chromosome Mapping; Escherichia coli; Genes; Glutamate Decarboxylase; Kinetics; Pantothenic Acid; Substrate Specificity; Uracil	1980
Improved colorimetric procedure for quantitating N-carbamoyl-beta-alanine with minimum dihydrouracil interference. Analytical biochemistry, 1982, May-15, Volume: 122, Issue:2 Topics: Alanine; beta-Alanine; Colorimetry; Spectrophotometry; Uracil	1982
Willardiines differentiate agonist binding sites for kainate- versus AMPA-preferring glutamate receptors in DRG and hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:6 Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Binding Sites; Dose-Response Relationship, Drug; Ganglia, Spinal; Hippocampus; Kainic Acid; Kinetics; Neurons; Pyrimidinones; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Time Factors; Uracil	1994
Binding of the new radioligand (S)-[3H]AMPA to rat brain synaptic membranes: effects of a series of structural analogues of the non-NMDA receptor agonist willardiine. Neuropharmacology, 1995, Volume: 34, Issue:4 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cycloleucine; Male; Pyrimidinones; Quinoxalines; Radioligand Assay; Rats; Rats, Wistar; Receptors, AMPA; Stereoisomerism; Synaptic Membranes; Tritium; Uracil	1995
Thiocyanate ions selectively antagonize AMPA-evoked responses in Xenopus laevis oocytes microinjected with rat brain mRNA. British journal of pharmacology, 1993, Volume: 109, Issue:3 Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Cell Membrane; Cerebellum; Electrophysiology; Female; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Microinjections; Neurons; Oocytes; Pregnancy; Pyrimidinones; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Thiocyanates; Uracil; Xenopus laevis	1993
3-Cyano-2,6-dihydroxypyridine (CNDP), a new potent inhibitor of dihydrouracil dehydrogenase. Journal of biochemistry, 1993, Volume: 114, Issue:6 Topics: Alanine; Animals; Antineoplastic Agents; Dihydrouracil Dehydrogenase (NAD+); Drug Synergism; Fluorouracil; Male; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Phosphorylation; Pyridines; Rats; Rats, Inbred Strains; Sarcoma, Yoshida; Tumor Cells, Cultured; Uracil	1993
Identity of D-3-aminoisobutyrate-pyruvate aminotransferase with alanine-glyoxylate aminotransferase 2. Biochimica et biophysica acta, 1993, Feb-13, Volume: 1156, Issue:2 Topics: Alanine; Alanine Transaminase; Animals; beta-Alanine; Fluorouracil; Kinetics; Liver; Precipitin Tests; Rats; Transaminases; Uracil	1993
Comparative studies on the metabolism of new fluorinated pyrimidine drugs in the liver by in vivo 19F magnetic resonance spectroscopic observation. Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:2 Topics: Alanine; Animals; Dihydrouracil Dehydrogenase (NAD+); Drug Interactions; Fluorouracil; Liver; Magnetic Resonance Spectroscopy; Male; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Pyridines; Rats; Rats, Wistar; Tegafur; Uracil	1993
Localisation and properties of AMPA-insensitive kainate sites: receptor autoradiography and gene expression in rat brain. Neuroscience letters, 1996, Feb-02, Volume: 204, Issue:1-2 Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Base Sequence; Brain; Brain Chemistry; Excitatory Amino Acid Agonists; Gene Expression Regulation; In Vitro Techniques; Male; Molecular Sequence Data; Pyrimidinones; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Uracil	1996
Synthesis of willardiine and 6-azawillardiine analogs: pharmacological characterization on cloned homomeric human AMPA and kainate receptor subtypes. Journal of medicinal chemistry, 1997, Oct-24, Volume: 40, Issue:22 Topics: Alanine; Cell Line; Excitatory Amino Acid Agonists; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Pyrimidinones; Radioligand Assay; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Proteins; Triazines; Uracil	1997
RNA polymerase II subunit Rpb9 regulates transcription elongation in vivo. The Journal of biological chemistry, 2000, Nov-10, Volume: 275, Issue:45 Topics: Alanine; Alleles; Antimetabolites; Cell Division; DNA, Complementary; Dose-Response Relationship, Drug; Fungal Proteins; Gene Deletion; Mutagenesis, Site-Directed; Nucleic Acid Hybridization; Phenotype; Protein Structure, Tertiary; RNA; RNA Polymerase II; Saccharomyces cerevisiae; Temperature; Transcription, Genetic; Uracil; Zinc	2000
Effects of the potent ampakine CX614 on hippocampal and recombinant AMPA receptors: interactions with cyclothiazide and GYKI 52466. Molecular pharmacology, 2000, Volume: 58, Issue:4 Topics: Alanine; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Cells, Cultured; Diuretics; Drug Interactions; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Humans; In Vitro Techniques; Male; Oxazines; Pyrimidinones; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Recombinant Proteins; Sodium Chloride Symporter Inhibitors; Tritium; Uracil	2000
Mutant cycle analysis of the active and desensitized states of an AMPA receptor induced by willardiines. Biochemistry, 2000, Oct-24, Volume: 39, Issue:42 Topics: Alanine; Animals; Anura; Benzothiadiazines; Binding Sites; Dose-Response Relationship, Drug; Ion Channel Gating; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Pyrimidinones; Receptors, AMPA; Uracil	2000
Interference of S-nitrosoglutathione with the binding of ligands to ionotropic glutamate receptors in pig cerebral cortical synaptic membranes. Neurochemical research, 2000, Volume: 25, Issue:8 Topics: Alanine; Animals; Binding, Competitive; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutathione; Kainic Acid; Kinetics; Ligands; Neuroprotective Agents; Nitroso Compounds; Piperazines; Pyrimidinones; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; S-Nitrosoglutathione; Swine; Synaptic Membranes; Uracil	2000
Reviving a dead enzyme: cytosine deaminations promoted by an inactive DNA methyltransferase and an S-adenosylmethionine analogue. Biochemistry, 2000, Nov-28, Volume: 39, Issue:47 Topics: Adenosine; Alanine; Cysteine; Cytosine; Deamination; DNA (Cytosine-5-)-Methyltransferases; DNA-Cytosine Methylases; Enzyme Inhibitors; Escherichia coli; Mutagenesis, Site-Directed; S-Adenosylmethionine; Serine; Uracil	2000
Ornithine carbamoyltransferase deficiency presenting with chorea in a female. Journal of inherited metabolic disease, 2000, Volume: 23, Issue:8 Topics: Alanine; Chorea; Female; Glutamine; Humans; Infant; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Uracil	2000
Calcium inhibits willardiine-induced responses in kainate receptor GluR6(Q)/KA-2. Neuroreport, 2001, Jan-22, Volume: 12, Issue:1 Topics: Alanine; Calcium Chloride; Cells, Cultured; GluK2 Kainate Receptor; Humans; Kidney; Membrane Potentials; Pyrimidinones; Receptors, Kainic Acid; Uracil	2001
The role of the cysteine residues of ThiI in the generation of 4-thiouridine in tRNA. The Journal of biological chemistry, 2001, Sep-07, Volume: 276, Issue:36 Topics: Alanine; Amino Acid Motifs; Bacterial Proteins; Carbon-Sulfur Lyases; Cloning, Molecular; Cysteine; Disulfides; Dithionitrobenzoic Acid; Escherichia coli; Escherichia coli Proteins; Iron; Models, Chemical; Mutagenesis, Site-Directed; Plasmids; RNA, Transfer; Spectrophotometry; Sulfur; Sulfurtransferases; Thiamine; Thiouridine; Time Factors; Ultraviolet Rays; Uracil	2001
Two-dimensional (17)O multiple quantum magic-angle spinning NMR of organic solids. Journal of the American Chemical Society, 2001, Sep-19, Volume: 123, Issue:37 Topics: Alanine; Benzoates; Glutamic Acid; Magnetic Resonance Spectroscopy; Molecular Structure; Oxygen Isotopes; Uracil	2001
The contribution of the methyl groups on thymine bases to binding specificity and affinity by alanine-rich mutants of the bZIP motif. Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:9 Topics: Alanine; Amino Acid Motifs; Amino Acid Substitution; Basic-Leucine Zipper Transcription Factors; Binding Sites; DNA; DNA-Binding Proteins; Fluorescence Polarization; G-Box Binding Factors; Mutation; Protein Binding; Thermodynamics; Thymine; Titrimetry; Transcription Factors; Uracil; Yeasts	2001
The novel antagonist 3-CBW discriminates between kainate receptors expressed on neonatal rat motoneurones and those on dorsal root C-fibres. British journal of pharmacology, 2002, Volume: 137, Issue:7 Topics: Alanine; Animals; Animals, Newborn; Benzodiazepines; Benzyl Compounds; Dose-Response Relationship, Drug; Evoked Potentials; Excitatory Amino Acid Antagonists; Motor Neurons; Nerve Fibers; Pyrimidinones; Quinoxalines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Spinal Nerve Roots; Time Factors; Uracil	2002
Structural requirements for novel willardiine derivatives acting as AMPA and kainate receptor antagonists. British journal of pharmacology, 2003, Volume: 138, Issue:6 Topics: Alanine; Animals; Animals, Newborn; Drug Antagonism; Evoked Potentials; Molecular Conformation; Molecular Structure; Nerve Fibers, Unmyelinated; Pyrimidinones; Rats; Receptors, AMPA; Receptors, Kainic Acid; Spinal Cord; Spinal Nerve Roots; Structure-Activity Relationship; Uracil	2003
Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal. Biochemistry, 2003, May-13, Volume: 42, Issue:18 Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Crystallography, X-Ray; Dimerization; Excitatory Amino Acid Agonists; Kainic Acid; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Pyrimidinones; Quinoxalines; Rats; Receptors, AMPA; Structure-Activity Relationship; Uracil	2003
Structural basis for partial agonist action at ionotropic glutamate receptors. Nature neuroscience, 2003, Volume: 6, Issue:8 Topics: Alanine; Animals; Cell Line; Crystallography, X-Ray; Electric Conductivity; Electrophysiology; Humans; Ion Channels; Ligands; Models, Biological; Molecular Conformation; Oocytes; Pyrimidinones; Receptors, AMPA; Uracil; Xenopus laevis	2003
Inhibition of willardiine-induced currents through rat GluR6/KA-2 kainate receptor channels by Zinc and other divalent cations. Neuroscience letters, 2003, Oct-02, Volume: 349, Issue:2 Topics: Alanine; Animals; Barium; Binding, Competitive; Calcium; Cations, Divalent; Cell Line, Transformed; Dose-Response Relationship, Drug; GluK2 Kainate Receptor; Humans; Magnesium; Membrane Potentials; Patch-Clamp Techniques; Pyrimidinones; Rats; Receptors, Kainic Acid; Uracil; Zinc	2003
beta-amino acid formation by tissue slices incubated with pyrimidines. The Journal of biological chemistry, 1953, Volume: 201, Issue:1 Topics: Alanine; Amino Acids; Butyrates; Lipid Metabolism; Liver; Pyrimidines; Thymine; Uracil	1953
Enzymic interconversion of hydrouracil and beta-ureidopropionic acid. Biochimica et biophysica acta, 1955, Volume: 18, Issue:3 Topics: Alanine; beta-Alanine; Uracil	1955
The catabolism of C14-labeled uracil, dihydrouracil, and beta-ureidopropionic acid in rat liver slices. The Journal of biological chemistry, 1957, Volume: 226, Issue:1 Topics: Alanine; Animals; beta-Alanine; Liver; Rats; Uracil; Urea	1957
The catabolism of C14-labeled uracil, dihydrouracil, and beta-ureidopropionic acid in the intact rat. The Journal of biological chemistry, 1957, Volume: 226, Issue:1 Topics: Alanine; Animals; beta-Alanine; Rats; Uracil; Urea	1957
[The free amino acids in the seeds of Acacia willardiana (Mimosaceae). Isolation of willardiin, a new plant amino acid which is probably L-beta-(3-uracil)-alpha-aminopropionic acid]. Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1959, Oct-30, Volume: 316 Topics: Acacia; Alanine; Amino Acids; Propionates; Seeds; Uracil	1959
[Messenger RNA, specific acceptor of L-amino acids in the presence of bacterial enzymes]. Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1963, Jul-08, Volume: 257 Topics: Alanine; Alcaligenes; Amino Acids; RNA; RNA, Bacterial; RNA, Messenger; Uracil; Valine; Yeasts	1963
EFFECT OF VANCOMYCIN ON BACILLUS SUBTILIS. Archives of biochemistry and biophysics, 1964, Volume: 105 Topics: Alanine; Antimetabolites; Bacillus subtilis; Bacterial Proteins; Bacteriolysis; Carbon Isotopes; Colorimetry; Glucose; Glutamates; Magnesium; Mucoproteins; Pentosephosphates; Peptides; Pharmacology; Proteins; Research; Spectrophotometry; Uracil; Vancomycin	1964
PATHWAY OF PYRIMIDINE BIOSYNTHESIS IN PREMETAMORPHIC TADPOLES. The Journal of biological chemistry, 1964, Volume: 239 Topics: Alanine; Animals; Anura; Aspartic Acid; Carbamates; Carbon Isotopes; Carboxy-Lyases; Glucose; Larva; Liver; Metabolism; Metamorphosis, Biological; Orotic Acid; Phosphates; Pyrimidines; Research; RNA; Succinates; Uracil	1964
ON THE MODE OF ACTION OF THE TETRACYCLINE ANTIBIOTICS IN STAPHYLOCOCCUS AUREUS. The Journal of biological chemistry, 1964, Volume: 239 Topics: Alanine; Anti-Bacterial Agents; Antimetabolites; Bacterial Proteins; Carbon Isotopes; Cell Division; Chloramphenicol; DNA; DNA, Bacterial; Glutamates; Lysine; Metabolism; Penicillin G; Pharmacology; Proteins; Research; Staphylococcus; Staphylococcus aureus; Tetracycline; Thymidine; Tritium; Uracil	1964
Barrier-free intermolecular proton transfer induced by excess electron attachment to the complex of alanine with uracil. The Journal of chemical physics, 2004, Apr-01, Volume: 120, Issue:13 Topics: Alanine; Anions; Electrons; Glycine; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Conformation; Protons; Solvents; Spectrum Analysis; Uracil	2004
Synthesis and pharmacology of willardiine derivatives acting as antagonists of kainate receptors. Journal of medicinal chemistry, 2005, Dec-01, Volume: 48, Issue:24 Topics: Alanine; Animals; Animals, Newborn; Calcium; Cell Line; Humans; In Vitro Techniques; Long-Term Potentiation; Mossy Fibers, Hippocampal; Nerve Fibers, Unmyelinated; Protein Subunits; Pyrimidinones; Radioligand Assay; Rats; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Proteins; Spinal Cord; Spinal Nerve Roots; Stereoisomerism; Structure-Activity Relationship; Uracil	2005
Structure-activity relationship studies on N3-substituted willardiine derivatives acting as AMPA or kainate receptor antagonists. Journal of medicinal chemistry, 2006, Apr-20, Volume: 49, Issue:8 Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cell Line; Drug Evaluation, Preclinical; Humans; In Vitro Techniques; Molecular Structure; Pyrimidinones; Rats; Receptors, Kainic Acid; Recombinant Proteins; Structure-Activity Relationship; Time Factors; Uracil	2006
3-hydroxypyridazine 1-oxides as carboxylate bioisosteres: a new series of subtype-selective AMPA receptor agonists. Neuropharmacology, 2006, Volume: 51, Issue:1 Topics: Alanine; Animals; Carboxylic Acids; Cerebral Cortex; Cloning, Molecular; Cyclic N-Oxides; Dose-Response Relationship, Drug; Electrophysiology; In Vitro Techniques; Models, Molecular; Molecular Mimicry; Oocytes; Pyridazines; Pyrimidinones; Radioligand Assay; Rats; Receptors, AMPA; Receptors, Glutamate; Recombinant Proteins; RNA, Complementary; Structure-Activity Relationship; Uracil; Xenopus laevis	2006
Neonatal hypoxic preconditioning involves vascular endothelial growth factor. Neurobiology of disease, 2007, Volume: 26, Issue:1 Topics: Aging; Alanine; Animals; Animals, Newborn; Antibodies, Blocking; Brain; Excitatory Amino Acid Agonists; Hypoxia, Brain; Ibotenic Acid; Injections, Intraperitoneal; Mice; Mice, Transgenic; Mutation; Promoter Regions, Genetic; Pyrimidinones; Recombinant Proteins; Uracil; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2; Weight Loss	2007
Inhibition of kainate receptors reduces the frequency of hippocampal theta oscillations. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Feb-28, Volume: 27, Issue:9 Topics: Alanine; Animals; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Long-Evans; Rats, Wistar; Receptors, Kainic Acid; Theta Rhythm; Uracil	2007
Synthesis and pharmacological characterization of N3-substituted willardiine derivatives: role of the substituent at the 5-position of the uracil ring in the development of highly potent and selective GLUK5 kainate receptor antagonists. Journal of medicinal chemistry, 2007, Apr-05, Volume: 50, Issue:7 Topics: Alanine; Animals; Animals, Newborn; Binding Sites; Calcium; Cell Line; Crystallography, X-Ray; Humans; In Vitro Techniques; Ligands; Models, Molecular; Motor Neurons; Nerve Fibers, Unmyelinated; Protein Conformation; Pyrimidinones; Rats; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Proteins; Spinal Nerve Roots; Stereoisomerism; Structure-Activity Relationship; Uracil	2007
Bioavailability of the amino acid-attached prodrug as a new anti-HIV agent in rats. Journal of veterinary science, 2007, Volume: 8, Issue:3 Topics: Administration, Oral; Alanine; Aminopyridines; Animals; Anti-HIV Agents; Area Under Curve; Biological Availability; Half-Life; Injections, Intravenous; Male; Prodrugs; Rats; Rats, Sprague-Dawley; Uracil	2007
Chemical interplay in the mechanism of partial agonist activation in alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. Biochemistry, 2008, Jan-08, Volume: 47, Issue:1 Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cell Line; Fluorescence Resonance Energy Transfer; Humans; Protein Binding; Protein Conformation; Protein Structure, Secondary; Pyrimidinones; Receptors, AMPA; Spectroscopy, Fourier Transform Infrared; Uracil	2008
NMR spectroscopy of the ligand-binding core of ionotropic glutamate receptor 2 bound to 5-substituted willardiine partial agonists. Journal of molecular biology, 2008, May-02, Volume: 378, Issue:3 Topics: Alanine; Binding Sites; Crystallography, X-Ray; Ligands; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Pyrimidinones; Receptors, AMPA; Uracil	2008
Estimated H-atom anisotropic displacement parameters: a comparison between different methods and with neutron diffraction results. Acta crystallographica. Section A, Foundations of crystallography, 2008, Volume: 64, Issue:Pt 4 Topics: Alanine; Algorithms; Anisotropy; Crystallography; Glycine; Hydrogen; Models, Chemical; Neutron Diffraction; Uracil; X-Ray Diffraction; Xylitol	2008
ACET is a highly potent and specific kainate receptor antagonist: characterisation and effects on hippocampal mossy fibre function. Neuropharmacology, 2009, Volume: 56, Issue:1 Topics: Action Potentials; Alanine; Animals; Calcium; Cell Line, Transformed; Crystallography, X-Ray; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Humans; In Vitro Techniques; Models, Molecular; Mossy Fibers, Hippocampal; Pyramidal Cells; Rats; Receptors, Kainic Acid; Synaptic Transmission; Transfection; Uracil	2009
Mechanism of partial agonism at the GluR2 AMPA receptor: Measurements of lobe orientation in solution. Biochemistry, 2008, Oct-07, Volume: 47, Issue:40 Topics: Alanine; Animals; Crystallography, X-Ray; Glutamic Acid; Kainic Acid; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Receptors, AMPA; Solutions; Uracil	2008
[2,3]-Sigmatropic rearrangements of 3-sulfinyl dihydropyrans: application to the syntheses of the cores of ent-dysiherbaine and deoxymalayamicin A. The Journal of organic chemistry, 2008, Nov-21, Volume: 73, Issue:22 Topics: Alanine; Bridged Bicyclo Compounds, Heterocyclic; Hydroxylation; Pyrans; Stereoisomerism; Sulfoxides; Uracil	2008
Mechanisms of antagonism of the GluR2 AMPA receptor: structure and dynamics of the complex of two willardiine antagonists with the glutamate binding domain. Biochemistry, 2009, May-12, Volume: 48, Issue:18 Topics: Alanine; Calorimetry; Crystallography, X-Ray; Excitatory Amino Acid Antagonists; Glutamic Acid; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Conformation; Radioligand Assay; Receptors, AMPA; Uracil	2009
Effects of the selective kainate receptor antagonist ACET on altered sensorimotor gating in a genetic model of reduced NMDA receptor function. Brain research, 2012, Mar-14, Volume: 1443 Topics: Alanine; Animals; Antipsychotic Agents; Carrier Proteins; Disease Models, Animal; Gene Knockdown Techniques; Isoxazoles; Mice; Nerve Tissue Proteins; Propionates; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Uracil	2012
Role of conformational dynamics in α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor partial agonism. The Journal of biological chemistry, 2012, Dec-21, Volume: 287, Issue:52 Topics: Alanine; Amino Acid Substitution; Fluorescence Resonance Energy Transfer; HEK293 Cells; Humans; Mutation, Missense; Protein Structure, Tertiary; Receptors, AMPA; Uracil	2012
Thermodynamics and mechanism of the interaction of willardiine partial agonists with a glutamate receptor: implications for drug development. Biochemistry, 2014, Jun-17, Volume: 53, Issue:23 Topics: Alanine; Animals; Binding Sites; Drug Design; Drug Partial Agonism; Drugs, Investigational; Entropy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hydrogen Bonding; Isoelectric Point; Kinetics; Ligands; Models, Molecular; Peptide Fragments; Protein Binding; Rats; Receptors, AMPA; Recombinant Fusion Proteins; Thermodynamics; Uracil	2014
A quantum biochemistry investigation of willardiine partial agonism in AMPA receptors. Physical chemistry chemical physics : PCCP, 2015, May-21, Volume: 17, Issue:19 Topics: Alanine; Drug Partial Agonism; Ligands; Models, Molecular; Protein Conformation; Quantum Theory; Receptors, AMPA; Thermodynamics; Uracil	2015
Dynamical differences of hemoglobin and the ionotropic glutamate receptor in different states revealed by a new dynamics alignment method. Proteins, 2017, Volume: 85, Issue:8 Topics: 2,3-Diphosphoglycerate; Alanine; Algorithms; Allosteric Site; Animals; Binding Sites; Excitatory Amino Acid Agonists; Halogenation; Hemoglobins; Humans; Kainic Acid; Ligands; Molecular Dynamics Simulation; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Rats; Receptors, AMPA; Sequence Alignment; Sequence Homology, Amino Acid; Thermodynamics; Uracil	2017
New insight into nucleo α-amino acids - Synthesis and SAR studies on cytotoxic activity of β-pyrimidine alanines. Bioorganic chemistry, 2020, Volume: 100 Topics: Alanine; Antineoplastic Agents; beta-Alanine; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Models, Molecular; Pyrimidines; Uracil	2020
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009