Compounds > alanine

alanine and ubp 310

alanine has been researched along with ubp 310 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's3 (37.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Dolman, NP; Ghosal, A; Jane, DE; Mayer, ML1
Du, M; Jayaraman, V; Rambhadran, A1
Jane, DE; Mulle, C; Perrais, D; Pinheiro, PS1
Atlason, PT; Eaves, RJ; Jane, DE; Mayo-Martin, MB; Molnár, E; Scholefield, CL1
Grosenbaugh, DK; Ross, BM; Wagley, P; Zanelli, SA1
Kumar, J; Kumari, J; Vinnakota, R1
Laloli, KJ; Li, KM; Lowth, A; Pickford, R; Rentsch, P; Stayte, S; Vissel, B1
Albanese, F; Bagnati, R; Cattaneo, S; Ciammola, A; Consalez, GG; Croci, L; Davoli, E; Di Fonzo, A; Mercatelli, D; Morari, M; Novello, S; Passafaro, M; Passoni, A; Regoni, M; Sassone, J; Serratto, GM; Taverna, S; Valtorta, F; Zanetti, L1

Other Studies

8 other study(ies) available for alanine and ubp 310

ArticleYear
Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Mar-15, Volume: 26, Issue:11

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Crystallography, X-Ray; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; Glutamic Acid; Hydrogen Bonding; Models, Molecular; Oocytes; Patch-Clamp Techniques; Protein Binding; Protein Conformation; Quinoxalines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Fusion Proteins; Thymine; Xenopus laevis

2006
Luminescence resonance energy transfer investigation of conformational changes in the ligand binding domain of a kainate receptor.
    The Journal of biological chemistry, 2008, Oct-03, Volume: 283, Issue:40

    Topics: Alanine; Cell Line; GluK2 Kainate Receptor; Humans; Ligands; Luminescent Measurements; Models, Molecular; Protein Structure, Tertiary; Receptors, Kainic Acid; Thymine

2008
Antagonism of recombinant and native GluK3-containing kainate receptors.
    Neuropharmacology, 2009, Volume: 56, Issue:1

    Topics: Alanine; Animals; Animals, Newborn; Benzodiazepines; Biophysics; Cell Line, Transformed; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hippocampus; Humans; In Vitro Techniques; Kainic Acid; Membrane Potentials; Mice; Mice, Knockout; Mossy Fibers, Hippocampal; Neuronal Plasticity; Patch-Clamp Techniques; Protein Subunits; Pyramidal Cells; Receptors, Kainic Acid; Recombinant Proteins; Synaptic Transmission; Thymine; Transfection

2009
Mapping the ligand binding sites of kainate receptors: molecular determinants of subunit-selective binding of the antagonist [3H]UBP310.
    Molecular pharmacology, 2010, Volume: 78, Issue:6

    Topics: Alanine; Animals; Animals, Newborn; Binding Sites; Binding, Competitive; Crystallography, X-Ray; HEK293 Cells; Humans; Ligands; Point Mutation; Protein Subunits; Protons; Rats; Rats, Wistar; Receptors, Kainic Acid; Thymine

2010
The Role of Kainate Receptors in the Pathophysiology of Hypoxia-Induced Seizures in the Neonatal Mouse.
    Scientific reports, 2018, 05-04, Volume: 8, Issue:1

    Topics: Alanine; Animals; Animals, Newborn; Disease Models, Animal; Disease Susceptibility; Electroencephalography; Hippocampus; Hypoxia; Mice; Mice, Knockout; Receptors, Kainic Acid; Seizures; Synaptic Potentials; Thymine

2018
Structural and Functional Insights into GluK3-kainate Receptor Desensitization and Recovery.
    Scientific reports, 2019, 07-16, Volume: 9, Issue:1

    Topics: Alanine; Animals; Binding Sites; Cryoelectron Microscopy; Crystallography, X-Ray; GluK3 Kainate Receptor; HEK293 Cells; Humans; Mutagenesis, Site-Directed; Polysaccharides; Protein Conformation; Rats; Receptors, Kainic Acid; Thymine

2019
The kainate receptor antagonist UBP310 but not single deletion of GluK1, GluK2, or GluK3 subunits, inhibits MPTP-induced degeneration in the mouse midbrain.
    Experimental neurology, 2020, Volume: 323

    Topics: Alanine; Animals; Dopaminergic Neurons; GluK2 Kainate Receptor; GluK3 Kainate Receptor; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Parkinsonian Disorders; Receptors, Kainic Acid; Thymine

2020
Pharmacological antagonism of kainate receptor rescues dysfunction and loss of dopamine neurons in a mouse model of human parkin-induced toxicity.
    Cell death & disease, 2020, 11-10, Volume: 11, Issue:11

    Topics: Alanine; Animals; Disease Models, Animal; Dopaminergic Neurons; Down-Regulation; Female; GluK2 Kainate Receptor; Male; Mice; Mice, Inbred C57BL; Mutation; Parkinson Disease; Receptors, Kainic Acid; Thymine; Ubiquitin-Protein Ligases

2020