alanine has been researched along with tryptophan in 645 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 305 (47.29) | 18.7374 |
| 1990's | 91 (14.11) | 18.2507 |
| 2000's | 150 (23.26) | 29.6817 |
| 2010's | 74 (11.47) | 24.3611 |
| 2020's | 25 (3.88) | 2.80 |
| Authors | Studies |
|---|---|
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S | 1 |
| Kördel, W; Schneider, F | 1 |
| Filutowicz, M; Kłopotowski, T; Wild, J | 1 |
| Chen, RF; Maly, M; Smith, PD | 1 |
| Rogerson, AC | 1 |
| Demonté, JP; Englert, A; Guillard, R; Prémilat, S | 1 |
| Behbehani, AW; Neuhoff, V; Quentin, CD | 1 |
| Aprison, MH; Lane, JD; McBride, WJ; Shea, PA; Smith, JE | 1 |
| Baram, T; Fridkin, M; Hazum, E; Koch, Y | 1 |
| Ashman, PU; Newport, GR; Page, CR; Seed, JR; Stibbs, HH | 1 |
| Wannemacher, RW | 1 |
| Alexandrov, S; Mepham, TB; Peters, AR | 1 |
| Davidson, CS; Fernstrom, JD; Hammarstrom-Wiklund, B; Munro, HN; Rand, WM; Wurtman, RJ | 1 |
| Garsky, VM; Lien, EL | 1 |
| Bouknight, RR; Sadoff, HL | 1 |
| Denizeau, F; Sourkes, TL | 1 |
| Hughes, JV; Johnson, TC | 1 |
| McDaniel, HG | 1 |
| Fontana, A; Savige, WE | 1 |
| Jones, RS; Kelly, GA; Meyer, JH; Spingola, LJ | 1 |
| Cooke, AR; Stephens, JR; Woolson, RF | 1 |
| Chrétien, M; Gilardeau, C; Lis, M; Smith, G | 1 |
| Korvatskiĭ, BG | 1 |
| Redpath, JL | 1 |
| Corwin, LM; Thorne, GM | 1 |
| Crisp, DM; Halestrap, AP; Mendes-Mourāo, J; Pogson, CI | 1 |
| Asch, HL; Read, CP | 1 |
| Umebachi, Y | 1 |
| Gerig, JT; McLeod, RS | 1 |
| Templer, H; Thistlethwaite, PJ | 1 |
| Heinrich, D; Kubli, F; Metz, J; Wesch, H | 1 |
| Bezkorovainy, A; Grohlich, D; Sly, DA | 1 |
| Goda, Y; Maitani, T; Suzuki, J; Takeda, M; Uchiyama, M; Yoshihira, K | 1 |
| Alesiani, M; Davolio, P; Lombardi, G; Moroni, F; Pellicciari, R; Russi, P | 1 |
| Belongia, EA; Gleich, GJ; Lin, F; Lundy, SK; Mayeno, AN | 1 |
| Floss, HG; Mocek, U; Siesel, B; Zhou, P | 1 |
| Brodie, MJ; Connick, JH; Heywood, GC; Sills, GJ; Stone, TW; Thompson, GG | 1 |
| Benamar, D; Daumas, P; Heitz, F; Lazaro, R; Mouden, R; Pullman, A; Ranjalahy-Rasoloarijao, L | 1 |
| Aubrey, KL; Thomas, GJ | 1 |
| Bermes, EW; Flanigan, RC; Holmes, EW; Kinzler, GJ | 1 |
| Brunie, S; Ghosh, G; Pelka, H; Schulman, LH | 1 |
| Cady, SG; Sono, M | 1 |
| Bogitsh, BJ; Davenport, GR | 1 |
| Merutka, G; Shalongo, W; Stellwagen, E | 1 |
| Bass, SH; Mulkerrin, MG; Wells, JA | 1 |
| Bergsma, DJ; Bossard, MJ; Brandt, M; Koser, PL; Levy, MA | 1 |
| Mital, R; Srivastava, TS | 1 |
| Cheng, J; Cheng, ZP; Wang, YF | 1 |
| Kurl, R; Sidransky, H; Verney, E | 1 |
| Hofnung, M; Martineau, P; Quiocho, FA; Spurlino, JC; Szmelcman, S | 1 |
| Bender, SL; Brzovic, P; Dunn, MF; Phillips, RS | 1 |
| Bakalian, MJ; Fernstrom, JD | 1 |
| Bender, DA; Danielian, PS; Njagi, EN | 1 |
| Kłopotowski, T; Walczak, W; Wild, J; Zakrzewska, B | 1 |
| Bou, S; Harada, N; Nagamatsu, A; Shimeno, H; Toda, A | 1 |
| Daumas, P; Heitz, F; Lazaro, R; Ranjalahy-Rasoloarijao, L | 1 |
| Wheeler, CP; Yudilevich, DL | 1 |
| Beale, D; Coadwell, J | 1 |
| Cheek, JM; Edmond, J; Jones, MR; Tamaki, J; Wu, PY | 1 |
| Ahl, PL; Khorana, HG; Mogi, T; Rothschild, KJ; Stern, LJ | 1 |
| Hopfinger, AJ; Johnson, ME; Yuan, CJ | 1 |
| Aoyagi, H; Kato, T; Lee, S; Mihara, H; Yamasaki, N; Yoshida, M | 1 |
| Collins-Lech, C; Sohnle, PG; Wagner, DK | 1 |
| Kiick, DM; Phillips, RS | 1 |
| Dunn, MF; Miles, EW; Phillips, RS; Roy, M | 1 |
| Andrews, JC; Short, SA | 1 |
| Chaouloff, F; Curzon, G; Kennett, GA; Merino, D; Serrurrier, B | 1 |
| Basova, NA; Kushak, RI | 1 |
| Dimaline, R; Martin, V | 1 |
| Cserháti, T; Szögyi, M | 1 |
| Johnson, LW; Smith, CH | 1 |
| Gaillard, JM; Tissot, R; Widmer, J | 1 |
| Karlsson, JO; Sjöstrand, J | 1 |
| Ljungstedt, I; Sjöholm, I | 1 |
| Deuel, TF; Prusiner, S | 1 |
| Kingdon, HS | 1 |
| Hachimori, A; Ito, M; Samejima, T | 1 |
| Burrill, P; Lerner, J; Miller, DS | 1 |
| Bentley, PH; Gregory, RA; Grossman, MI; Tracy, HJ | 1 |
| Garrick-Silversmith, L; Torriani, A | 1 |
| Ingram, LO; Jensen, RA | 1 |
| Chamove, AS; Harlow, HF; Kerr, GR | 1 |
| Callahan, HJ; Liberti, PA; Maurer, PH | 1 |
| Dikow, A; Lolova, I | 1 |
| Asatoor, AM; Navab, F | 1 |
| Curzon, G; Green, AR | 1 |
| Knowles, WS; Sabacky, MJ; Vineyard, BD | 1 |
| Fernstrom, JD; Larin, F; Mostafapour, S; Wurtman, RJ | 1 |
| Hallberg, D; Soda, M | 1 |
| Redhardt, A | 1 |
| Hirsh, DI; Lipmann, F | 1 |
| Jensen, RA | 1 |
| Meybeck, A; Windle, JJ | 1 |
| Froncish, W; Kalmanson, AE; Kharitonenkov, IG; Yuferov, VP | 1 |
| Hughes, RC; Stokes, E; Tanner, PJ | 1 |
| Srinivasan, VT; Van de Vorst, A | 1 |
| Horecker, RL; Melloni, E; Pontremoli, S; Sia, CL; Traniello, S | 1 |
| Allen, CM | 1 |
| Bauer, K; Kleinkauf, H; Lipmann, F; Roskoski, R | 1 |
| Fischer, D; Kössel, H; Schott, H | 1 |
| Ferreira, SH; Greene, LJ; Stewart, JM | 1 |
| Pownall, HJ; Smith, LC | 1 |
| Crippa, PR; Tedeschi, RA; Vecli, A | 1 |
| Aune, KC; Gallagher, JG; Gotto, AM; Morrisett, JD | 1 |
| Donelli, MG; Garattini, S; Rosso, R | 1 |
| Deuel, TF; Turner, DC | 1 |
| Segal, A; Stadtman, ER | 1 |
| Aktin, E; Bergisadi, N; Güven, KC; Koyuncuoglu, H | 1 |
| Kornecki-Gerrity, EH; Penney, DG | 1 |
| Hashimoto, T; Miyazawa, S; Sakurai, T; Shindo, Y | 1 |
| Mandel, P; Trayhurn, P; Virmaux, N | 1 |
| Allsopp, MN; Hullin, RP; Rees, JR | 1 |
| Asafov, GB; Ekisenina, NI; Ivanova, LM; Lumel'skiĭ, VIa; Smagin, VG | 1 |
| Lindig, OH; Mitlin, N; Thompson, AC; Wiygul, G | 1 |
| Andrews, AT | 1 |
| Melera, PW; Momeni, C; Rusch, HP | 1 |
| Asatoor, AM; Chadha, A; Milne, MD; Prosser, DI | 1 |
| Amons, R; Groene, A; Möller, W; Terhorst, C | 1 |
| Sunde, ML | 1 |
| Colowick, SP; Schmidt, JJ | 1 |
| Doctor, BP; Sodd, MA | 1 |
| Christensen, HN; Quay, S | 1 |
| Halpern, YS | 1 |
| Creighton, TE | 1 |
| Calhoun, DH; Jensen, RA | 1 |
| Griffin, GJ; Pass, T | 1 |
| Fekl, W | 1 |
| Tanooka, H | 1 |
| Coulson, RA; Herbert, JD | 1 |
| Alimov, IIu; Iur'eva, EA; Marchenko, ZM | 1 |
| Aleksandrov, VIa; Tabidze, DD | 1 |
| Abita, JP; Bonsen, PP; de Haas, GH; Lazdunski, M; Pieterson, WA | 1 |
| Dembinski, A; Konturek, SJ; Radecki, T; Thor, P | 1 |
| Christiansen, PA; Reiser, S | 3 |
| Bassett, RA; Chain, EB; Corbett, K | 1 |
| Herbert, JD | 1 |
| Hill, RJ | 1 |
| Trayhurn, P; van Heyningen, R | 1 |
| Buxton, BH; Curzon, G; Murray-Lyon, IM; Stewart, DA; Williams, R | 1 |
| Iversen, LL; Snodgrass, SR | 1 |
| Lapidot, Y; Rappoport, S | 1 |
| Dimicoli, JL; Hélène, C | 1 |
| Stadtman, ER; Woolfolk, CA | 1 |
| Kingdon, HS; Stadtman, ER | 1 |
| Bock, RM; Cherayil, J; Faulkner, RD; Hapel, A; Jones, DS; Khorana, HG; Söll, D | 1 |
| Blumenthal, A; Ezekiel, DH | 1 |
| Oxender, DL; Piperno, JR | 1 |
| Ginsburg, A | 1 |
| Degani, Y; Patchornik, A; Spande, TF; Witkop, B | 1 |
| Vagelos, PR; Van Den Bosch, H; Williamson, JR | 1 |
| Staehelin, M | 1 |
| Deppe, CS; Koch, AL | 1 |
| Milne, MD | 1 |
| Berger, H; Brammar, WJ; Yanofsky, C | 1 |
| Kumagai, H; Miles, EW | 1 |
| Hunt, DE | 2 |
| DeCicco, BT; Stukus, PE | 1 |
| Buu-Hoï, NP; Hauspie, R; Lambelin, G; Nicolle, J | 1 |
| Reynolds, JA; Schlesinger, MJ; Schlesinger, S | 1 |
| Deuel, TF; Stadtman, ER | 1 |
| Barabas, G; Kushner, DJ; Mehta, BM | 1 |
| Lines, DR; Waisman, HA | 1 |
| Dolif, D; Jürgens, P | 1 |
| Pettersson, U; Prage, L | 1 |
| Crawford, IP; Maurer, R | 1 |
| Prescott, JM; Wagner, FW; Wilkes, SH | 1 |
| Smissman, EE; Warner, VD | 1 |
| Fisher, HF; Prough, RA | 1 |
| Matta, MS; Silver, MS | 1 |
| Husain, I; Norris, RF; Poupard, JA | 1 |
| Adams, GE; Aldrich, JE; Bisby, RH; Cundall, RB; Redpath, JL; Willson, RL | 1 |
| Altman, KI; Sobocinski, PZ | 1 |
| Snell, EE | 1 |
| Fletcher, PL; Hash, JH | 1 |
| Schultz, SG; Strecker, CK; Yu-Tu, L | 1 |
| Brunel, C; Cathala, G | 1 |
| Bender, ML; Valenzuela, P | 1 |
| Benuck, M; Lajtha, A; Stern, F | 1 |
| Morishita, S; Muramatsu, K; Odagiri, H; Takeuchi, H | 1 |
| Fernstrom, JD; Larin, F; Wurtman, RJ | 1 |
| Gromova, ES; Shabarova, ZA; Tyaglov, BV | 1 |
| Horton, HR; Naik, VR | 1 |
| Shearer, TR; Suttie, JW | 1 |
| Bezanson, GS; Vining, LC | 1 |
| Calloway, DH; Margen, S; Weller, LA | 1 |
| Markelova, SI; Zharikova, GG | 3 |
| Gabel, D; Katchalski, E; Steinberg, IZ | 1 |
| Brewer, HB; Bronzert, TJ; Fales, HM; Milne, GW; Nagai, Y; Pisano, JJ | 1 |
| Potoczek, S | 1 |
| Kotelchuck, D; Scheraga, HA | 1 |
| Ito, T; Moore, GE | 1 |
| Hellman, A; Hellman, KB; Martin, DH; Novelli, GD; Yang, WK | 1 |
| Lynn, KR; Winchester, RV | 1 |
| Guest, JR; Yanofsky, C | 1 |
| Beguin, S; Kepes, A | 1 |
| Glöde, J; Gross, H; Lisý, V; Podŭska, K; Rudinger, J; Skoda, J | 1 |
| Matthews, DB | 1 |
| Dusek, Z; Hradec, J | 1 |
| Hoshino, S; Tsubota, H | 1 |
| Kimmel, HS; Saifer, A | 1 |
| Hanck, A; Schreiner, A | 1 |
| Brewer, JM; Fairwell, T; Lovins, RE; Travis, J | 1 |
| Castagnoli, N; Chain, EB; Corbett, K; Thomas, R | 1 |
| MacKenzie, RE; McCormick, DB; Wu, FY | 1 |
| Jacquez, JA; Sherman, JH; Terris, J | 1 |
| Clayton, BE; Heeley, AF; Heeley, M | 1 |
| Coulson, RA; Hernandez, T | 1 |
| Crawford, MA; Gale, MM; Hansen, IL; Somers, K | 1 |
| Fürst, P; Josephson, B; Vinnars, E | 1 |
| Baranova, IP; Egorov, NS | 1 |
| Kerly, M; Spruyt, JE | 1 |
| Baños, G; Daniel, PM; Moorhouse, SR; Pratt, OE | 1 |
| Flory, B; Krassner, SM | 1 |
| Miyatake, A; Wada, H; Watanabe, T | 1 |
| Leonard, BE; Liska, KJ | 1 |
| Bubenshchikova, SN; Katrukha, GS; Kharchenko, LI; Silaev, AB; Trufonova, ZhP | 1 |
| Gusev, EI | 1 |
| Chibata, I; Fuse, N; Mori, T; Tosa, T | 1 |
| Demeyer, DI; Henderickx, HK | 1 |
| Gray, E; Paulus, H | 1 |
| Chou, C; Larin, FF; Rose, CM; Wurtman, RJ | 1 |
| Szarvas, T; Váradi, J; Verzár-Petri, G | 1 |
| Brown, HH | 1 |
| Steenbergen, ST; Weinberg, ED | 1 |
| Bairos, MA; Bairos, VA | 1 |
| Schneider, G | 1 |
| Hoffmeister, H; Tarnowski, W | 1 |
| Indada, Y; Matsushima, A; Nomoto, M; Sakurai, K; Shibata, K | 1 |
| Farid, SA; Kozloff, LM | 1 |
| Barbato, IM; Barbato, LM | 1 |
| Oravec, M; Sourkes, TL | 1 |
| McCalla, AG; Yang, HJ | 1 |
| Beisel, WR; Dangerfield, HG; Feigin, RD | 1 |
| Abdel Kader, MM; Abdel Wahab, F; Ata, AA; Emara, SH; Soliman, L | 1 |
| Gordon, WG; Greenberg, R; Pepper, L; Thompson, MP | 1 |
| Cook, DA; Henderson, LM | 1 |
| Gineitis, AA; Vinogradova, IA; Vorobyev, VI | 1 |
| Buchanan, BB; Evans, MC; Matsubara, H | 1 |
| Matchett, WH | 1 |
| Jacquez, JA; Sherman, JH | 1 |
| Castles, JJ; Moyer, AN; Wool, IG | 1 |
| Huang, JM; Wang, IS; Wang, KT | 1 |
| Friedmann, T; Johnson, P | 1 |
| Altman, KJ; Deknudt, G; Gerber, GB; Kennes, F; Reuter, AM | 1 |
| Kuz'mina, VV | 1 |
| Andreeva, LA | 1 |
| Buzina, TP; Pokidova, NV | 1 |
| Brown, DM; Michael, AF | 2 |
| Braams, R | 1 |
| Hubbard, JS; Stadtman, ER | 1 |
| Adamson, LF; Ingbar, SH | 1 |
| Morino, Y; Snell, EE | 1 |
| Blum, JJ; Owens, I | 1 |
| Drummond, KN; Michael, AF | 1 |
| Ikawa, M | 1 |
| Kneer, N; Lardy, HA; Veneziale, CM; Walter, P | 1 |
| Abasov, IT | 1 |
| Nelson, J; Pfeffer, M; Ressler, C | 1 |
| Kuroda, Y | 1 |
| Fuji, M; Fukumoto, Y; Nagamatsu, A; Shimeno, H | 2 |
| Ho, TL; Horner, BL; Jones, GH; McRae, GI; Nestor, JJ; Vickery, BH | 1 |
| Baratova, LA; Kazdobina, IS; Ugriumova, GA; Uvarova, RN; Vinogradova, ID | 1 |
| Cohen, LA; Miles, EW; Phillips, RS | 1 |
| Bohnert, HJ; Burkard, G; Crouse, EJ; Gordon, K; Heiser, D; Keller, M; Mubumbila, M; Steinmetz, A; Weil, JH | 1 |
| Ciferri, O; Riccardi, G; Sora, S | 1 |
| Adams, DG; Carr, NG | 1 |
| Gahl, WA; Raiford, D; Schulman, JD; Steinherz, R; Tietze, F | 1 |
| Gueguen, P; Hervé, G; Padron, M; Perbal, B | 1 |
| Poillon, WN | 1 |
| Pogson, CI; Smith, SA | 1 |
| Bass, R; Dillehay, L; Englesberg, E; Hedegaard, HB; Moffett, J | 1 |
| Fukumoto, Y; Nagamatsu, A; Shimeno, H; Toda, A | 1 |
| Cooke, AR; Cooke, HJ; Pfankuche, L | 1 |
| Esaki, N; Kishimoto, K; Manning, JM; Soda, K; Sugio, S; Yoshimura, T | 1 |
| Coggins, JR; James, R; Kleanthous, C; Leech, AP | 1 |
| Camp, S; Quinn, DM; Radić, Z; Taylor, P; Vellom, DC | 1 |
| Ergul, A; Puett, D | 1 |
| Behravan, G; Goodtzova, K; Gräslund, A; Ingemarson, R; Rova, U; Thelander, L | 1 |
| Abdo, S; Alharbi, S; Alkarmi, T; Alnaqib, M; Dar, FK; Galadari, S; Ijaz, MK | 1 |
| Adachi, J; Gomez, M; Smith, CC; Sternberg, EM | 1 |
| Hawkins, RA; Peterson, DR; Sánchez del Pino, MM | 1 |
| Adachi, J; Fujiwara, S; Mio, T; Naito, T; Nishimura, A; Sumino, K; Tatsuno, Y; Ueno, Y | 1 |
| Birdsall, NJ; Lazareno, S; Matsui, H | 1 |
| Belikov, VM; Dementieva, IS; Faleev, NG; Gogoleva, OI; Zakomirdina, LN | 1 |
| Milla, ME; Sauer, RT | 1 |
| al-Rabiee, R; Chiappinelli, VA; Fiordalisi, JJ; Grant, GA | 1 |
| Hayashi, H; Hirotsu, K; Kagamiyama, H; Kuramitsu, S; Metzler, CM; Metzler, DE; Miyahara, I; Mollova, ET; Scott, RD; Yano, T | 1 |
| Coggins, JR; Kelly, SM; Lindsay, JG; Malarkey, K; McKnight, J; Miles, JS; Munro, AW; Price, NC; Thomson, AJ | 1 |
| Banci, L; Bertini, I; Ferrer, JC; Mauk, AG; Morris, IK; Smith, KM; Smith, M; Turano, P | 1 |
| Carpenedo, R; Chiarugi, A; Costantino, G; Mahmoud, MR; Mattoli, L; Moroni, F; Natalini, B; Pellicciari, R; Sadeghpour, BM | 1 |
| Cosgrove, JW; Latham, PS; Sidransky, H; Verney, E | 1 |
| Barber, A; Pérez, M; Ponz, F | 1 |
| Allenmark, SG; Andersson, S; Guiochon, G; Jacobson, SC | 1 |
| Graham-Lorence, S; Ortiz de Montellano, PR; Peterson, JA; Tuck, SF | 1 |
| Gilbert, HJ; Hazlewood, GP; Huskisson, NS; Poole, DM; Virden, R | 1 |
| Arvidson, DN; Hatt, JK; Pecoraro, FS; Pfau, J; Shapiro, M; Youderian, P | 1 |
| Baldwin, RL; Chakrabartty, A; Kortemme, T; Padmanabhan, S | 1 |
| Hagiwara, Y; Kawase, Y; Sato, F | 1 |
| Malthouse, JP; Milne, JJ | 1 |
| Choe, S; Stevens, CF; Sullivan, JM | 1 |
| Collins, A; Gruninger, RH; Jin, R; Johnson, DL; Jolliffe, LK; McMahon, FJ; Middleton, SA; Mulcahy, LS; Tullai, J | 1 |
| Andracki, M; Bowen, SL; Chappell, DA; Fry, GL; Inoue, I; Lalouel, JM; Medh, JD; Ruben, S; Strickland, DK | 1 |
| Lee, S; Naime, D; Okubo, Y; Redman, C; Reid, M; Sistonen, P; Son, S; Wu, X | 1 |
| Garinot-Schneider, C; James, R; Kleanthous, C; Moore, GR; Pommer, AJ | 1 |
| Fujita, N; Ishihama, A; Murakami, K | 1 |
| Brown, WR | 1 |
| Latham, P; Schwartz, A; Sidransky, H; Verney, E | 1 |
| Adachi, J; Gomez, M; Smith, CC; Sternberg, EM; Tatsuno, Y; Ueno, Y | 1 |
| Meyer, K; Simat, T; Steinhart, H; van Wickern, B | 1 |
| Broersma, RJ; Burkhart, JP; Kutcher, LW; Malikayil, JA; Mehdi, S; Neises, B; Peet, NP; Schatzman, GL; Schreuder, HA; Tardif, C | 1 |
| Sidransky, H; Verney, E | 1 |
| Chuang, H; Collins, A; Jan, LY; Jan, YN | 1 |
| Sagnella, DE; Voth, GA | 1 |
| Baumann, C; Chen, Xp; Fernandez, B; Gollnick, P; Hoffman, R; Militello, K; Yang, M | 1 |
| Bonomo, RP; Carima, L; Corradini, R; Cucinotta, V; D'Alessandro, F; Impellizzeri, G; Maccarrone, G; Marchelli, R; Rizzarelli, E; Sartor, G; Vecchio, G | 1 |
| Finn, SE; Greenblatt, EP; Hanson, KK; Harris, RA; Harrison, NL; Koltchine, VV; Krasowski, MD; Mascia, MP; Mihic, SJ; Valenzuela, CF; Wick, MJ; Ye, Q | 1 |
| Braun, P; Kaback, HR; Persson, B; von Heijne, G | 1 |
| Douglas, J; Hinton, JF; Snow, A; Washburn-McCain, AM | 1 |
| Aoki, M; Hachimori, A; Tsuji, E; Uchiumi, T | 1 |
| Cho, H; Plapp, BV | 1 |
| Jernström, B; Johansson, AS; Mannervik, B; Seidel, A; Stenberg, G; Sundberg, K; Widersten, M | 1 |
| Bahnson, BJ; Chin, JK; Colby, TD; Goldstein, BM; Klinman, JP | 1 |
| Barone, G; Catanzano, F; Fusi, P; Graziano, G; Tortora, P | 1 |
| Matalon, R; Warner, DR; Weinstein, LS; Weng, G; Yu, S | 1 |
| Battistoni, A; Caccuri, AM; Chiessi, E; Federici, G; Lahm, A; Lo Bello, M; Mazzetti, AP; Nuccetelli, M; Oakley, AJ; Parker, MW; Ricci, G; Tramontano, A | 1 |
| Aulie, A; Kanui, TI; Sjaastad, OV; Velle, W | 1 |
| Bonn, G; Fiechtner, B; Glossmann, H; Huck, CW; Moebius, FF; Soellner, KE | 1 |
| Gráf, L; Hudáky, P; Kaslik, G; Venekei, I | 1 |
| Baskakov, IV; Bolen, DW | 1 |
| Britt, RD; Diner, BA; Peloquin, JM; Tang, XS | 1 |
| Phillips, RS; Welch, M | 1 |
| Kirley, TL; Lewis Carl, SA; Smith, TM | 1 |
| Beard, WA; Bebenek, K; Darden, TA; Howard, KJ; Kunkel, TA; Le Grice, SF; Levin, JG; Powell, MD; Wilson, SH | 1 |
| Balashov, SP; Ebrey, TG; Gennis, RB; Maeda, A; Tomson, FL | 1 |
| Golovine, SY; Hecht, SM; Short, GF | 1 |
| Jordan, F; Li, H | 1 |
| Dixon, RW; Kollman, P | 1 |
| Hilbers, CW; Pepermans, HA; Prompers, JJ | 1 |
| DenBesten, PK; Gao, C; Li, W; Machule, D | 1 |
| Choi, G; Choi, KY; Jang, DS; Joo, S; Kim, DH; Kim, JS; Nam, GH; Oh, BH | 1 |
| Kato, J; Kobayashi, H; Morioka, H; Ohtsuka, E; Stewart, JD | 1 |
| Albritton, LM; Zavorotinskaya, T | 1 |
| Brown, W; Carpenter, KA; Godbout, C; Hodzic, L; Payza, K; Pou, C; Roberts, E; Schmidt, R; Yue, SY | 1 |
| Cook, WJ; McDonald, JM; Micoli, KJ; Pan, G; Williams, JP; Wu, Y | 1 |
| Meunier, JC; Moisand, C; Mollereau, C; Mouledous, L; Topham, CM | 1 |
| Beard, WA; Bebenek, K; Forgacs, E; Kunkel, TA; Latham, GJ; Lloyd, RS; Prasad, R; Wilson, SH | 1 |
| Budisa, N; Fourmy, D; Huber, R; Loidl, G; Moroder, L; Musiol, HJ; Poirot, S | 1 |
| Kallenbach, NR; Taudte, S; Xin, H | 1 |
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| Bottecchia, C; Noël, T | 1 |
| Fatima, S; Hafeez, A; Ijaz, AIA; Memon, AA; Waseem, M | 1 |
| Kuusisto, J; Laakso, M; Smith, U; Stancáková, A; Vangipurapu, J | 1 |
| Granneman, J; Gros, P; Heck, AJR; Huisman, S; Kuiper, JK; Neviani, V; Rodenburg, RNP; van Bergen En Henegouwen, PMP; van de Waterbeemd, M; van Deventer, S; van Spriel, AB; Wörner, TP; Wortel, IMN; Xenaki, KT | 1 |
| Chen, Y; Ding, W; Lin, S; Wu, J; Yang, Y; Zang, J; Zhang, B; Zhao, H | 1 |
| Chen, W; Qu, C; Wang, S; Wu, J; Zhang, S | 1 |
| Greathouse, DV; Koeppe, RE; McKay, MJ | 1 |
| Bertoša, B; Bolt, EL; He, L; Ivančić-Baće, I; Killelea, T; Markulin, D; Matković, M; Matošević, ZJ; Mitić, D | 1 |
| Bredenbeck, J; Budisa, N; Deniz, E; Durkin, PM; Eberl, KB; Gulzar, A; Kaml, R; Löffler, JG; Stock, G; Valiño-Borau, L; Wolf, S | 1 |
| Bertran, MT; Calder, EDD; Joshi, D; Rowley, J; Walport, LJ; Wu, Y | 1 |
| Chen, YF; Jiang, S; Shen, YM; Tao, JH; Wang, L | 1 |
| Ahmad, R; Azizan, KA; Baharum, SN; Goh, KJ; Goh, YK; Ong, CE | 1 |
| Olberg, A; Sioud, M; Zhang, Q | 1 |
| Gao, JM; Han, H; Liu, C; Qi, J; Sui, D; Tan, S; Wang, P; Xia, X; Xie, C | 1 |
| Kim, M; Shin, HE; Won, CW | 1 |
| Chen, X; Ge, T; He, Z; Wang, J; Yuan, H; Zhang, L | 1 |
| Cheng, Y; Guo, Y; Jiang, W; Liu, C; Qian, H; Yang, F; Yao, W; Zhao, Y | 1 |
| DI, LQ; Huang, X; Lu, YY; Luo, ZC; Qi, MY; Shan, JJ; Zhang, W | 1 |
| Cui, Y; Feng, C; Gao, H; Li, D; Mao, H; Wang, C; Wei, X; Yang, J; Zhu, J | 1 |
| Filipovic, MR; Kreir, M; Moparthi, L; Moparthi, VK; Sinica, V; Vignane, T; Vlachova, V; Zygmunt, PM | 1 |
| Abarike, ED; Amenyogbe, E; Ayisi, CL; Chen, G; Fu, WJ; Huang, JS; Luo, J; Wang, ZL | 1 |
| Brito, F; Curcio, HFQ; da Silva Fidalgo, TK | 1 |
| Fujihara, A; Inoue, K | 2 |
| An, J; Jia, X; Li, X; Liu, R; Liu, S; Mo, Y; Wei, X; Zhang, S; Zhang, Y; Zhou, L | 1 |
| Chen, M; Gong, J; Han, D; Li, F; Wang, D; Wang, Y; Wei, J; Zhang, T; Zhou, L | 1 |
| Duan, Y; Lai, J; Li, L; Shao, L; Wang, J; Wang, Y; Xing, X; Yang, Z | 1 |
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
8 review(s) available for alanine and tryptophan
| Article | Year |
|---|---|
Utilization of D- and DL- amino acids and analogs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Histidine; Isomerism; Keto Acids; Leucine; Methionine; Nutritional Requirements; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1972 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Selective cleavage and modification of peptides and proteins.
Topics: Alanine; Aspartic Acid; Chemical Phenomena; Chemistry; Chymotrypsin; Cysteine; Glutamates; Glycine; Hydrogen-Ion Concentration; Methionine; Muramidase; Oxidation-Reduction; Peptides; Phenylalanine; Proline; Proteins; Pyrrolidines; Ribonucleases; Serine; Succinates; Threonine; Tryptophan | 1970 |
Transport of amino acids and peptides in the gut and the kidney.
Topics: Adult; Alanine; Amino Acids; Animals; Biological Transport, Active; Digestive System; Glycine; Hartnup Disease; Histidine; Humans; Hydrolysis; Intestinal Absorption; Kidney; Kidney Tubules; Leucine; Lysine; Methionine; Peptides; Phenylalanine; Proteins; Rats; Serine; Threonine; Tryptophan; Valine | 1971 |
The developmental biology of heterocyst and akinete formation in cyanobacteria.
Topics: Alanine; Ammonium Chloride; Bacterial Proteins; Cell Division; Cyanobacteria; Light; Methionine Sulfoximine; Rifampin; Tryptophan | 1981 |
Effects of tryptophan related compounds on nuclear regulatory control. Possible role in the eosinophilia-myalgia syndrome.
Topics: Alanine; Animals; Drug Contamination; Eosinophilia-Myalgia Syndrome; Humans; Liver; Nuclear Envelope; Proteins; Receptors, Cytoplasmic and Nuclear; RNA; Tryptophan | 1996 |
Photocatalytic Modification of Amino Acids, Peptides, and Proteins.
Topics: Alanine; Amino Acids; Catalysis; Cysteine; Light; Methionine; Oxidation-Reduction; Peptides; Proteins; Tryptophan | 2019 |
Periodontal disease metabolomics signatures from different biofluids: a systematic review.
Topics: Alanine; Butyrates; Formates; gamma-Aminobutyric Acid; Humans; Lactates; Metabolomics; Mouthwashes; Periodontal Diseases; Periodontitis; Phenylalanine; Propionates; Tryptophan; Tyrosine; Valine | 2022 |
3 trial(s) available for alanine and tryptophan
| Article | Year |
|---|---|
Daily rhythms in the concentrations of various amino acids in human plasma.
Topics: Adolescent; Adult; Alanine; Amino Acids; Circadian Rhythm; Cysteine; Dietary Proteins; Glutamates; Glycine; Humans; Isoleucine; Male; Methionine; Phenylalanine; Tryptophan; Tyrosine | 1968 |
Effect of l-tryptophan and its metabolites on food passage from the crop in chicks.
Topics: Administration, Oral; Alanine; Animals; Asparagine; Chickens; Crop, Avian; Gastrointestinal Motility; Glycine; Kynurenic Acid; Male; Quinolinic Acid; Tryptophan | 2018 |
Effects of autochthonous strains mixture on gut microbiota and metabolic profile in cobia (Rachycentron canadum).
Topics: Alanine; Albumins; Alkaline Phosphatase; Amino Acids; Amylases; Animal Feed; Animals; Aspartate Aminotransferases; ATP-Binding Cassette Transporters; Cellulose; Cholesterol; Diet; Fishes; Galactose; Gastrointestinal Microbiome; Glucose; Lipase; Metabolome; Nucleotides; Pepsin A; Perciformes; Purines; Receptors, Antigen, T-Cell; Receptors, Colony-Stimulating Factor; Triglycerides; Trypsin; Tryptamines; Tryptophan | 2022 |
634 other study(ies) available for alanine and tryptophan
| Article | Year |
|---|---|
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2022 |
Chemical modification of two tryptophan residues abolishes the catalytic activity of aminoacylase.
Topics: Alanine; Amidohydrolases; Amino Acids; Azo Compounds; Azoles; Bromosuccinimide; Histidine; Hydrogen-Ion Concentration; Lysine; Succinimides; Tetrazoles; Tosyl Compounds; Tosylphenylalanyl Chloromethyl Ketone; Tryptophan; Tyrosine | 1976 |
Utilization of D-amino acids by dadR mutants of Salmonella typhimurium.
Topics: Alanine; Amino Acids; D-Amino-Acid Oxidase; Glucose; Histidine; Methionine; Mutation; Pyruvates; Salmonella typhimurium; Stereoisomerism; Substrate Specificity; Tryptophan | 1978 |
The fluorescence of fluorescamine-amino acids.
Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry, Physical; Fluorescamine; Hydrogen-Ion Concentration; Kinetics; Leucine; Proline; Spectrometry, Fluorescence; Spiro Compounds; Tryptophan | 1978 |
Modifiers of heterocyst repression and spacing and formation of heterocysts without nitrogenase in the cyanobacterium Anabaena variabilis.
Topics: Alanine; Cyanobacteria; Enzyme Induction; gamma-Glutamyltransferase; Methionine Sulfoximine; Nitrogenase; Tryptophan | 1979 |
Theoretical conformational analysis of three [Trp4, Met5]-enkephalin analogs related to non-radiative energy transfer [proceedings].
Topics: Alanine; Endorphins; Energy Transfer; Enkephalins; Glycine; Methionine; Protein Conformation; Structure-Activity Relationship; Tryptophan | 1979 |
Neurochemical aspects of post-tetanic potentiation of monosynaptic reflexes in the cat spinal cord. I. Analysis of amino acids at maximum of potentiation.
Topics: Action Potentials; Alanine; Amino Acids; Animals; Aspartic Acid; Cats; Electric Stimulation; Female; gamma-Aminobutyric Acid; Glutamine; Glycine; Isoleucine; Leucine; Male; Motor Neurons; Muscle Contraction; Reflex, Monosynaptic; Spinal Cord; Synaptic Transmission; Tryptophan; Tyrosine | 1975 |
A method for concurrent measurement of picomole quantities of acetylcholine, choline, dopamine, norepinephrine, serotonin, 5-hydroxytryptophan, 5-hydroxyindoleacetic acid, tryptophan, tyrosine, glycine, aspartate, glutamate, alanine, and gamma-aminobutyri
Topics: 5-Hydroxytryptophan; Acetylcholine; Alanine; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Choline; Chromatography, Ion Exchange; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glycine; Hydroxyindoleacetic Acid; Male; Methods; Microchemistry; Neurotransmitter Agents; Norepinephrine; Rats; Serotonin; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1975 |
Resistance to enzymic degradation of LH-RH analogues possessing increased biological activity.
Topics: Alanine; Animals; Gonadotropin-Releasing Hormone; Hypothalamus; Leucine; Methionine; Peptide Hydrolases; Pituitary Gland; Pituitary Gland, Anterior; Rats; Stereoisomerism; Structure-Activity Relationship; Tryptophan | 1977 |
Alteration of free serum amino acids in voles infected with Trypanosoma brucei gambiense.
Topics: Alanine; Amino Acids; Animals; Arvicolinae; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Male; Proline; Serine; Threonine; Trypanosomiasis, African; Tryptophan; Tyrosine; Valine | 1977 |
Key role of various individual amino acids in host response to infection.
Topics: Alanine; Amino Acids; Animals; Carbohydrate Metabolism; Glutamine; Humans; Infections; Liver; Muscle Proteins; Muscles; Organ Specificity; Phenylalanine; Phlebotomus Fever; Proteins; Starvation; Structure-Activity Relationship; Tryptophan; Typhoid Fever | 1977 |
Effects of increased supply of essential amino acids on the metabolism of the isolated perfused guinea-pig mammary gland.
Topics: Alanine; Amino Acids, Essential; Animals; Female; Guinea Pigs; In Vitro Techniques; Mammary Glands, Animal; Methionine; Milk Proteins; Perfusion; Serine; Tryptophan | 1979 |
Diurnal variations in plasma concentrations of tryptophan, tryosine, and other neutral amino acids: effect of dietary protein intake.
Topics: Adult; Alanine; Amino Acids; Circadian Rhythm; Dietary Proteins; Glycine; Humans; Isoleucine; Leucine; Male; Middle Aged; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1979 |
Prolonged suppression of insulin release by a somatostatin analog.
Topics: Alanine; Animals; Blood Glucose; Glucagon; Insulin; Kinetics; Male; Rats; Somatostatin; Tryptophan | 1978 |
Tryptophan catabolism in Bacillus megaterium.
Topics: Alanine; Arginine; Bacillus megaterium; Catechols; Cell-Free System; Enzyme Induction; Enzyme Repression; Glucose; Hydrolases; Kynurenine; ortho-Aminobenzoates; Oxidation-Reduction; Oxygen Consumption; Oxygenases; Tryptophan | 1975 |
Regional transport of tryptophan in rat brain.
Topics: Alanine; Animals; Brain; Cerebellum; Corpus Striatum; Hypothalamus; Isoleucine; Kinetics; Male; Rats; Reticular Formation; Serotonin; Synaptosomes; Tryptophan | 1977 |
The effects of hyperphenylalaninaemia on the concentrations of aminoacyl-transfer ribonucleic acid in vivo. A mechanism for the inhibition of neural protein synthesis by phenylalanine.
Topics: Acylation; Alanine; Amino Acyl-tRNA Synthetases; Animals; Brain Chemistry; Formyltetrahydrofolates; Leucine; Lysine; Methionine; Mice; Nerve Tissue Proteins; Phenylalanine; RNA, Transfer; Tryptophan | 1977 |
A comparison of effect of insulin on hepatic metabolites, gluconeogenesis, and ketogenesis.
Topics: Alanine; Animals; Aspartic Acid; Blood Glucose; Carnitine; Citrates; Decanoic Acids; Fasting; Fatty Acids; Fatty Acids, Nonesterified; Gluconeogenesis; Glucose; Insulin; Ketone Bodies; Lactates; Liver; Liver Glycogen; Malates; Male; Pyruvate Carboxylase; Pyruvates; Rats; Tryptophan | 1977 |
Modification of tryptophan to oxindolylalanine by dimethyl sulfoxide-hydrochloric acid.
Topics: Alanine; Dimethyl Sulfoxide; Hydrochloric Acid; Muramidase; Oxidation-Reduction; Peptides; Tryptophan | 1977 |
Canine gut receptors mediating pancreatic responses to luminal L-amino acids.
Topics: Alanine; Amino Acids; Animals; Bicarbonates; Dogs; Intestines; Leucine; Methionine; Pancreas; Perfusion; Phenylalanine; Proteins; Receptors, Drug; Secretin; Stimulation, Chemical; Tryptophan; Valine | 1976 |
Osmoltye and tryptophan receptors controlling gastric emptying in the dog.
Topics: Alanine; Animals; Disaccharides; Dogs; Dose-Response Relationship, Drug; Gastrointestinal Motility; Lysine; Mannitol; Methionine; Monosaccharides; Pressoreceptors; Stomach; Tryptophan | 1976 |
Isolation of a new lipolytic-melanotropic peptide from human pituitary glands.
Topics: Alanine; Biological Assay; Chromatography; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Humans; Isoelectric Focusing; Lipid Metabolism; Peptides; Pituitary Gland; Pituitary Gland, Anterior; Pituitary Hormones, Anterior; Radioimmunoassay; Skin Pigmentation; Tryptophan | 1976 |
[Aminoacid composition of the blood serum in patients with toxic goiter].
Topics: Adolescent; Adult; Alanine; Amino Acids; Female; Goiter; Humans; Hyperthyroidism; Isoleucine; Leucine; Lysine; Male; Middle Aged; Threonine; Tryptophan; Valine | 1976 |
Letter: The sensitivity of E. coli phage T6 to inactivation by selective inorganic radicals.
Topics: Alanine; Bromine; Buffers; Butanols; Coliphages; Dose-Response Relationship, Radiation; Electrons; Free Radicals; Leucine; Radiation Effects; Radiation-Sensitizing Agents; Thiocyanates; Tryptophan | 1975 |
Mutations affecting aromatic amino acid transport in Escherichia coli and Salmonella typhimurium.
Topics: Alanine; Amino Acids; Biological Transport, Active; Chromosome Mapping; Escherichia coli; Ethidium; Genes; Glycine; Mutation; Phenylalanine; Plasmids; Salmonella typhimurium; Tryptophan; Tyrosine | 1975 |
The involvement of mitochondrial pyruvate transport in the pathways of gluconeogenesis from serine and alanine in isolated rat and mouse liver cells.
Topics: Alanine; Animals; Cinnamates; Gluconeogenesis; Glutamine; Glycerol; Lactates; Liver; Mice; Mitochondria, Liver; Oxygen Consumption; Pyruvates; Rats; Serine; Tryptophan | 1975 |
Membrane transport in Schistosoma mansoni: transport of amino acids by adult males.
Topics: Alanine; Amino Acids; Animals; Arginine; Biological Transport; Chromatography; Cysteine; Female; Glutamates; Glycine; Kinetics; Male; Methionine; Mice; Proline; Schistosoma mansoni; Tryptophan | 1975 |
Yellow pigments in the wings of Papilio xuthus (papilionid butterfly).
Topics: Alanine; Animals; Butterflies; Dopamine; Lepidoptera; Pigments, Biological; Tryptophan | 1975 |
Attempted synthesis of 2-methylalanyl-L-prolyl-L-tryptophan. An unexpected result.
Topics: Alanine; Amino Acid Sequence; Oligopeptides; Proline; Tryptophan | 1976 |
Flash photolysis of aqueous tryptophan, alanyl tryptophan and tryptophyl alanine.
Topics: Alanine; Dipeptides; Oxygen; Photolysis; Quantum Theory; Solutions; Tryptophan | 1976 |
[The pattern of distribution of free amino acids in human amniotic fluid related to the duration of pregnancy. Part I: Changes in concentration in normal pregnancy (author's transl)].
Topics: Alanine; Amino Acids; Amniotic Fluid; Chromatography, Gas; Cysteine; Female; Gestational Age; Glycine; Humans; Hydroxyproline; Methionine; Ornithine; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1976 |
Cleavage of human serum transferrin with N-bromosuccinimide.
Topics: Alanine; Aspartic Acid; Bromosuccinimide; Electrophoresis, Polyacrylamide Gel; Glutamine; Humans; Peptide Fragments; Protein Binding; Succinimides; Transferrin; Tryptophan | 1976 |
3-anilino-L-alanine, structural determination of UV-5, a contaminant in EMS-associated L-tryptophan samples.
Topics: Alanine; Chromatography, High Pressure Liquid; Eosinophilia-Myalgia Syndrome; Humans; Magnetic Resonance Spectroscopy; Tryptophan | 1992 |
Nicotinylalanine increases the formation of kynurenic acid in the brain and antagonizes convulsions.
Topics: Alanine; Animals; Anticonvulsants; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Extracellular Matrix; Hippocampus; Kidney; Kynurenic Acid; Liver; Male; Niacin; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine; Tryptophan | 1992 |
3-(Phenylamino)alanine, a novel aniline-derived amino acid associated with the eosinophilia-myalgia syndrome: a link to the toxic oil syndrome?
Topics: Alanine; beta-Alanine; Brassica; Chromatography, High Pressure Liquid; Drug Contamination; Eosinophilia-Myalgia Syndrome; Fatty Acids, Monounsaturated; Plant Oils; Rapeseed Oil; Spain; Tryptophan; United States | 1992 |
Biosynthesis of pyrrolnitrin. Incorporation of 13C, 15N double-labelled D- and L-tryptophan.
Topics: Alanine; Carbon Isotopes; Dipeptides; Nitrogen Isotopes; Pseudomonas; Pyrrolnitrin; Stereoisomerism; Tryptophan | 1992 |
Nicotinylalanine increases cerebral kynurenic acid content and has anticonvulsant activity.
Topics: Alanine; Animals; Anticonvulsants; Brain Chemistry; Electroshock; In Vitro Techniques; Kidney; Kynurenic Acid; Liver; Male; Mice; Mice, Inbred Strains; Niacin; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Tryptophan | 1992 |
How can the aromatic side-chains modulate the conductance of the gramicidin channel? A new approach using non-coded amino acids.
Topics: Alanine; Cations, Monovalent; Circular Dichroism; Gramicidin; Ion Channels; Lipid Bilayers; Signal Transduction; Spectrum Analysis; Tryptophan | 1991 |
Raman spectroscopy of filamentous bacteriophage Ff (fd, M13, f1) incorporating specifically-deuterated alanine and tryptophan side chains. Assignments and structural interpretation.
Topics: Alanine; Capsid; Coliphages; Deuterium; DNA, Bacterial; DNA, Single-Stranded; DNA, Viral; Nucleic Acid Conformation; Protein Conformation; Spectrum Analysis, Raman; Tryptophan | 1991 |
Free amino acids during chronic cyclosporine A toxicity in intact and partially nephrectomized rats.
Topics: Alanine; Amino Acids; Animals; Body Weight; Cyclosporins; Dose-Response Relationship, Drug; Kidney Glomerulus; Male; Methylhistidines; Nephrectomy; Nitrogen; Rats; Rats, Inbred F344; Tryptophan | 1991 |
Activation of methionine by Escherichia coli methionyl-tRNA synthetase.
Topics: Adenosine Monophosphate; Alanine; Amino Acid Sequence; Arginine; Aspartic Acid; Bacterial Proteins; Base Sequence; Catalysis; Enzyme Activation; Escherichia coli; Glutamine; Methionine; Methionine-tRNA Ligase; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Substrate Specificity; Transfer RNA Aminoacylation; Tryptophan | 1991 |
1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-[3-benzo(b)thienyl]-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenase.
Topics: Alanine; Animals; Benzofurans; Binding, Competitive; Circular Dichroism; Ferric Compounds; Ferrous Compounds; Kinetics; Rabbits; Spectrophotometry; Tryptophan; Tryptophan Oxygenase | 1991 |
The in vitro effects of various lysosomotropic agents on the gut of Schistosoma mansoni schistosomula.
Topics: Acridine Orange; Alanine; Amino Acids; Ammonium Chloride; Animals; Chloroquine; Dipeptides; Esters; Hydrogen-Ion Concentration; Leucine; Microscopy, Electron; Microscopy, Fluorescence; Schistosoma mansoni; Tryptophan | 1991 |
A model peptide with enhanced helicity.
Topics: Alanine; Amino Acid Sequence; Circular Dichroism; Hydrogen-Ion Concentration; Molecular Sequence Data; Peptides; Protein Conformation; Tryptophan | 1991 |
A systematic mutational analysis of hormone-binding determinants in the human growth hormone receptor.
Topics: Alanine; Amino Acid Sequence; Antibodies, Monoclonal; Binding Sites; Circular Dichroism; Cysteine; Fluorescence; Genetic Variation; Growth Hormone; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Somatotropin; Tryptophan; Tyrosine | 1991 |
A single Trp121 to Ala121 mutation in human cyclophilin alters cyclosporin A affinity and peptidyl-prolyl isomerase activity.
Topics: Alanine; Amino Acid Isomerases; Amino Acid Sequence; Base Sequence; Carrier Proteins; Cloning, Molecular; Cyclosporins; Escherichia coli; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Peptidylprolyl Isomerase; Recombinant Proteins; Restriction Mapping; Substrate Specificity; Tryptophan | 1991 |
Synthesis, characterization, and DNA binding studies of some mixed-ligand platinum(II) complexes of 1,10-phenanthroline and amino acids.
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Cattle; Cisplatin; DNA; Ethidium; Glycine; Intercalating Agents; Leucine; Magnetic Resonance Spectroscopy; Phenanthrolines; Phenylalanine; Platinum; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1990 |
[Effects of amino acids on the membrane potential of toad oocytes and the underlying mechanism].
Topics: Alanine; Amino Acids; Animals; Bufo bufo; Female; Leucine; Lysine; Membrane Potentials; Oocytes; Progesterone; Tryptophan | 1990 |
Comparison of effects of L-tryptophan and a tryptophan analog, D,L-beta-(1-naphthyl)alanine, on processes relating to hepatic protein synthesis in rats.
Topics: Alanine; Animals; Female; Glucosamine; Leucine; Liver; Nucleoside-Triphosphatase; Phosphoric Monoester Hydrolases; Polynucleotide Adenylyltransferase; Polyribosomes; Protein Biosynthesis; Rats; Rats, Inbred Strains; Tryptophan | 1990 |
Genetic approach to the role of tryptophan residues in the activities and fluorescence of a bacterial periplasmic maltose-binding protein.
Topics: Alanine; ATP-Binding Cassette Transporters; Bacterial Proteins; Base Sequence; Biological Transport; Carbohydrate Sequence; Carrier Proteins; Chemotaxis; Escherichia coli; Escherichia coli Proteins; Maltose; Maltose-Binding Proteins; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutation; Periplasmic Binding Proteins; Protein Engineering; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan | 1990 |
Mechanism of binding of substrate analogues to tryptophan indole-lyase: studies using rapid-scanning and single-wavelength stopped-flow spectrophotometry.
Topics: Alanine; Aminobutyrates; Bacterial Proteins; Escherichia coli; Kinetics; Oxindoles; Protein Binding; Spectrophotometry; Substrate Specificity; Tryptophan; Tryptophanase | 1990 |
Effects of L-tryptophan and other amino acids on electroencephalographic sleep in the rat.
Topics: Alanine; Animals; Computers; Electroencephalography; Fluoxetine; Male; Rats; Rats, Inbred Strains; Sleep; Tryptophan; Valine | 1990 |
Tryptophan metabolism in vitamin B6-deficient mice.
Topics: Alanine; Animals; Cells, Cultured; Formates; Liver; Male; Mice; Mice, Inbred Strains; Tryptophan; Vitamin B 6 Deficiency; Weight Gain | 1990 |
Two distinct types of mutations conferring to Escherichia coli K12 capability of D-tryptophan utilization.
Topics: Alanine; Amino Acid Oxidoreductases; Chromosome Mapping; Deamination; Escherichia coli; Genes, Bacterial; Mutation; Operon; Phenotype; Substrate Specificity; Tryptophan | 1987 |
Inhibition of rat liver tryptophan pyrrolase activity and elevation of brain tryptophan concentration by administration of DL-alpha-amino-beta-pyridinepropanoic acid (pyridylalanine) analogs.
Topics: Alanine; Animals; Brain; Hydroxyindoleacetic Acid; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Structure-Activity Relationship; Tryptophan; Tryptophan Oxygenase | 1987 |
Gramicidin A analogs: influence of the substitution of the tryptophans by naphthylalanines.
Topics: Alanine; Conductometry; Gramicidin; Lipid Bilayers; Naphthalenes; Spectrophotometry, Infrared; Structure-Activity Relationship; Tryptophan | 1989 |
Lysine and alanine transport in the perfused guinea-pig placenta.
Topics: 2,4-Dinitrophenol; Alanine; Animals; Biological Transport; Dinitrophenols; Guinea Pigs; Lysine; Perfusion; Phenylalanine; Placenta; Tryptophan | 1989 |
Some observations on the replacement of the conserved amino acid residues of immunoglobulin domains.
Topics: Alanine; Amino Acids; beta 2-Microglobulin; Computer Graphics; Cysteine; Immunoglobulin Constant Regions; Immunoglobulin Variable Region; Immunoglobulins; Leucine; Serine; Tryptophan; Tyrosine | 1989 |
Plasma amino acid concentrations in premature infants: effect of sampling site.
Topics: Alanine; Amino Acids; Aspartic Acid; Blood Specimen Collection; Capillaries; Chromatography, High Pressure Liquid; Glycine; Heel; Histidine; Humans; Infant, Newborn; Infant, Premature; Serine; Tryptophan; Veins | 1989 |
Substitution of amino acids in helix F of bacteriorhodopsin: effects on the photochemical cycle.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Bacteriorhodopsins; Glutamates; Glutamic Acid; Glutamine; Glycine; Hydrogen Bonding; Kinetics; Leucine; Molecular Sequence Data; Mutation; Phenylalanine; Photochemistry; Proline; Protons; Serine; Tryptophan | 1989 |
QSAR and molecular shape analysis of aryl-substituted alanine analogs as antigelling agents.
Topics: Alanine; Gels; Hemoglobins; Models, Biological; Molecular Conformation; Molecular Structure; Phenylalanine; Solubility; Structure-Activity Relationship; Tryptophan | 1989 |
The spectroscopic analysis for binding of amphipathic and antimicrobial model peptides containing pyrenylalanine and tryptophan to lipid bilayer.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Circular Dichroism; Fluorescent Dyes; Indicators and Reagents; Lipid Bilayers; Molecular Sequence Data; Peptides; Protein Binding; Protein Conformation; Pyrenes; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan | 1989 |
Inhibition of neutrophil killing of Candida albicans pseudohyphae by substances which quench hypochlorous acid and chloramines.
Topics: Alanine; Candida albicans; Chloramines; Humans; Hypochlorous Acid; Mannitol; Methionine; Neutrophils; Oxidation-Reduction; Peroxidase; Superoxides; Tryptophan | 1986 |
Mechanistic deductions from multiple kinetic and solvent deuterium isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Escherichia coli tryptophan indole-lyase.
Topics: Alanine; Binding, Competitive; Catalysis; Cysteine; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lyases; Oxindoles; Pyridoxal Phosphate; Solvents; Tryptophan; Tryptophanase | 1988 |
Detection and identification of transient intermediates in the reactions of tryptophan synthase with oxindolyl-L-alanine and 2,3-dihydro-L-tryptophan. Evidence for a tetrahedral (gem-diamine) intermediate.
Topics: Alanine; Diamines; Escherichia coli; Kinetics; Mathematics; Models, Theoretical; Oxindoles; Protein Binding; Spectrophotometry; Tryptophan; Tryptophan Synthase | 1988 |
opp-lac Operon fusions and transcriptional regulation of the Escherichia coli trp-linked oligopeptide permease.
Topics: Alanine; Anaerobiosis; beta-Galactosidase; DNA, Recombinant; Escherichia coli; Gene Expression Regulation; Genes; Genes, Bacterial; Genetic Linkage; Lac Operon; Leucine; Membrane Transport Proteins; Oligopeptides; Operon; Salmonella typhimurium; Transcription, Genetic; Tryptophan | 1986 |
Amino acid analysis demonstrates that increased plasma free tryptophan causes the increase of brain tryptophan during exercise in the rat.
Topics: Alanine; Amino Acids; Animals; Brain; gamma-Aminobutyric Acid; Glycine; Lysine; Male; Physical Exertion; Rats; Rats, Inbred Strains; Stress, Physiological; Tryptophan | 1986 |
[Various routes of L-tryptophan transport in the small intestine of the chick].
Topics: Alanine; Animals; Chickens; In Vitro Techniques; Intestinal Absorption; Kinetics; Sodium; Threonine; Tryptophan; Valine | 1986 |
Sodium dependence of amino acid-stimulated acid secretion in the conscious rat.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Gastric Acid; Histidine; Hydrogen-Ion Concentration; Male; Rats; Rats, Inbred Strains; Sodium; Tryptophan | 1988 |
Amino acid-amino acid interactions studied by charge-transfer chromatography.
Topics: Alanine; Amino Acids; Chromatography, Thin Layer; Hydrogen-Ion Concentration; Indicators and Reagents; Phenylalanine; Sodium Chloride; Spectrophotometry, Ultraviolet; Tryptophan | 1988 |
Neutral amino acid transport systems of microvillous membrane of human placenta.
Topics: Alanine; Amino Acids; Aminobutyrates; Biological Transport, Active; Cysteine; Female; Humans; Leucine; Microvilli; Placenta; Pregnancy; Sodium; Tryptophan | 1988 |
L-tyrosine and L-tryptophan transport in red blood cells in normal subjects. Effects of other amino acids, temperature and medium of incubation.
Topics: Alanine; Biological Transport; Erythrocytes; Humans; Kinetics; Leucine; Temperature; Tryptophan; Tyrosine | 1986 |
Axonal transport of proteins in retinal ganglion cells. Amino acid incorporation into rapidly transported proteins and distribution of radioactivity to the lateral geniculate body and the superior colliculus.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Axonal Transport; Cysteine; Female; Geniculate Bodies; Glycine; Histidine; Leucine; Lysine; Male; Methionine; Nerve Tissue Proteins; Optic Nerve; Phenylalanine; Proline; Rabbits; Retina; Superior Colliculi; Tritium; Tryptophan | 1972 |
Studies on the tryptophan and drug-binding properties of human serum albumin fragments by affinity chromatography and circular dichroism measurements.
Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry; Chlordiazepoxide; Chromatography, Affinity; Circular Dichroism; Cyanogen Bromide; Dialysis; Electrophoresis, Disc; Ethylenediamines; Humans; Mathematics; Peptide Fragments; Peptides; Phenothiazines; Phenylbutazone; Polysaccharides; Protein Binding; Protein Conformation; Serum Albumin; Tryptophan; Ultraviolet Rays | 1973 |
Regulation of glutamine synthetase from Bacillus subtilis by divalent cations, feedback inhibitors, and L-glutamine.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Ammonia; Bacillus subtilis; Feedback; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Glycine; Histidine; Kinetics; Magnesium; Manganese; Tryptophan | 1974 |
Feedback inhibition of glutamine synthetase from green pea seeds.
Topics: Adenosine Monophosphate; Alanine; Animals; Chromatography, Gel; Escherichia coli; Glutamate-Ammonia Ligase; Glycine; Histidine; Kinetics; Liver; Plants; Rats; Seeds; Species Specificity; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors; Tryptophan | 1974 |
Some properties of glutamine synthetase from baker's yeast.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Amino Acids; Cations, Divalent; Electrophoresis; Glutamate-Ammonia Ligase; Glutamates; Glycine; Histidine; Molecular Weight; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Tryptophan; Ultracentrifugation | 1974 |
Distinct components of neutral amino acid transport in chick small intestine.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Chickens; Glycine; Intestinal Absorption; Intestine, Small; Leucine; Male; Proline; Tryptophan | 1974 |
Nature of the gastric secretagogue in Zollinger-Ellison tumours.
Topics: Alanine; Aspartic Acid; Gastrins; Glutamates; Glycine; Humans; In Vitro Techniques; Leucine; Methionine; Proline; Spectrum Analysis; Tryptophan; Tyrosine; Zollinger-Ellison Syndrome | 1967 |
Macromolecular syntheses during germination and outgrowth of Bacillus subtilis spores.
Topics: Alanine; Amino Acids; Bacillus subtilis; Bacterial Proteins; Carbon Isotopes; Culture Media; Glucose; Hydrogen-Ion Concentration; Microscopy, Phase-Contrast; Mutation; RNA, Bacterial; Spores; Spores, Bacterial; Tryptophan; Uracil | 1973 |
Growth inhibition by L-phenylalanine in Agmenellum quadruplicatum. A clue to some amino acid interrelationships.
Topics: Alanine; Aldehyde-Lyases; Amino Acids; Culture Media; Cyanobacteria; Heptoses; Isoleucine; Leucine; Methionine; Mutation; Phenylalanine; Phenylpyruvic Acids; Stereoisomerism; Tetroses; Time Factors; Tryptophan; Tyrosine | 1973 |
Learning in monkeys fed elevated amino acid diets.
Topics: Alanine; Amino Acids; Animals; Diet; Discrimination Learning; Female; Food; Glycine; Haplorhini; Histidine; Humans; Learning; Macaca; Monkey Diseases; Phenylalanine; Phenylketonurias; Pregnancy; Problem Solving; Reward; Tryptophan; Tyrosine | 1973 |
Physicochemical studies of Ca++ controlled antigen antibody systems.
Topics: Alanine; Animals; Antigen-Antibody Complex; Antigen-Antibody Reactions; Antigens; Binding Sites, Antibody; Calcium; Cations, Divalent; Circular Dichroism; Edetic Acid; Glutamates; Immunoglobulin Fab Fragments; Immunoglobulin G; Kinetics; Peptides; Precipitin Tests; Rabbits; Sheep; Spectrophotometry; Time Factors; Tritium; Tryptophan; Tyrosine; Ultracentrifugation | 1974 |
[Histochemical evidence of aminotransferases. I. Method of histochemical demonstration of a few aminotransferases in rat organs (author's transl)].
Topics: Alanine; Animals; Asparagine; Dihydrolipoamide Dehydrogenase; Electron Transport; Glutamate Dehydrogenase; Glutamates; Glycine; Histocytochemistry; Isoleucine; Ketoglutaric Acids; Kidney; Leucine; Liver; Phenylalanine; Rats; Transaminases; Tryptophan; Tyrosine; Valine | 1974 |
Studies on intestinal absorption of amino acids and a dipeptide in a case of Hartnup disease.
Topics: Adult; Alanine; Amino Acids; Chromatography, Paper; Dipeptides; Female; Hartnup Disease; Histidine; Humans; Intestinal Absorption; Intestine, Small; Niacinamide; Phenylalanine; Radiography; Tryptophan | 1970 |
The effect of tryptophan metabolites on brain 5-hydroxytryptamine metabolism.
Topics: Alanine; Allopurinol; Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Carboxy-Lyases; Histamine; Kynurenic Acid; Kynurenine; Male; Methanol; Methyldopa; Mixed Function Oxygenases; Niacinamide; Nicotinic Acids; Nitroglycerin; ortho-Aminobenzoates; Phenylalanine; Phenylbutyrates; Picolinic Acids; Pyridines; Pyridoxal Phosphate; Pyridoxine; Rats; Serotonin; Sulfuric Acids; Time Factors; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1970 |
Catalytic asymmetric hydrogenation.
Topics: Acylation; Alanine; Amino Acids; Catalysis; Cinnamates; Dihydroxyphenylalanine; Fenclonine; Hydrogenation; Ligands; Optical Rotation; Phenylalanine; Phosphines; Tryptophan | 1973 |
Brain catechol synthesis: control by train tyrosine concentration.
Topics: Alanine; Animals; Benserazide; Brain Chemistry; Dihydroxyphenylalanine; Fenclonine; Histidine; Leucine; Lysine; Male; Phenylalanine; Rats; Tryptophan; Tyrosine | 1974 |
Hepatic blood flow changes following intravenous infusion of various single amino acids in dogs. 3.
Topics: Alanine; Amino Acids; Animals; Arginine; Cysteine; Dogs; Electromagnetic Phenomena; Hepatic Artery; Hepatic Veins; Injections, Intravenous; Liver; Liver Circulation; Lysine; Phenylalanine; Portal System; Rheology; Stimulation, Chemical; Threonine; Tryptophan | 1974 |
[Application of electron spin resonance in radiation biology].
Topics: Alanine; Blood Proteins; Caseins; Electron Spin Resonance Spectroscopy; Globins; Glycine; Phenylalanine; Radiation Effects; Tobacco Mosaic Virus; Tryptophan; Tyrosine; Valine | 1965 |
The divergence in reactivity of aminoacyl transfer ribonucleic acid synthetases of Escherichia coli with hydroxylamine.
Topics: Alanine; Amino Acids; Carbon Isotopes; Chromatography, Ion Exchange; Cysteine; Escherichia coli; Glutamates; Glycine; Hydroxylamines; Isoleucine; Kinetics; Leucine; Ligases; Lysine; Methionine; Periodic Acid; Phenylalanine; RNA, Bacterial; RNA, Transfer; Threonine; Tryptophan; Tyrosine | 1968 |
Metabolic interlock. Regulatory interactions exerted between biochemical pathways.
Topics: Alanine; Bacillus subtilis; Cyclohexanecarboxylic Acids; Cyclohexanes; Diphosphates; Feedback; Histidine; Hydro-Lyases; Kinetics; Leucine; Metabolism; Methionine; Phenylalanine; Pyruvates; Thiophenes; Tryptophan; Tyrosine | 1969 |
Electron paramagnetic resonance study of x-ray and gamma-ray irradiated peptides in the solid state.
Topics: Alanine; Amino Acid Sequence; Cobalt Isotopes; Electron Spin Resonance Spectroscopy; Free Radicals; Glycine; Peptides; Phenylalanine; Radiation Effects; Temperature; Tryptophan; Tyrosine | 1969 |
Electron paramagnetic resonance study of free radical products of the reaction of ninhydrin with amino acids, peptides and proteins.
Topics: Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Dipeptides; Electron Spin Resonance Spectroscopy; Ethanol; Free Radicals; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Lysine; Peptides; Phenylalanine; Proline; Proteins; Serine; Solutions; Tryptophan; Tyrosine; Valine | 1970 |
Cell-wall thickening in Bacillus subtilis. Comparison of thickened and normal walls.
Topics: Alanine; Aspartic Acid; Bacillus subtilis; Bacteriolysis; Cell Wall; Chloramphenicol; Chromatography, DEAE-Cellulose; Culture Media; Diphosphates; Metabolism; Microscopy, Electron; Mucoproteins; Pentosephosphates; Phosphates; Phosphorus Isotopes; Polymers; Polysaccharides, Bacterial; Tritium; Tryptophan | 1970 |
Formation of free radicals in aliphatic and aromatic amino acids by trapped electrons: an E.S.R. study.
Topics: Alanine; Amino Acids; Electron Spin Resonance Spectroscopy; Free Radicals; Glycine; Phenylalanine; Photochemistry; Radiochemistry; Spectrum Analysis; Tryptophan; Tyrosine | 1971 |
Rabbit liver fructose 1,6-diphosphatase. Properties of the native enzyme and their modification by subtilisin.
Topics: Adenosine Monophosphate; Alanine; Amino Acids; Ammonium Sulfate; Animals; Carboxypeptidases; Centrifugation, Density Gradient; Chemical Precipitation; Chromatography, Ion Exchange; Electrophoresis; Endopeptidases; Fructose-Bisphosphatase; Fructosephosphates; Hydrogen-Ion Concentration; Liver; Macromolecular Substances; Molecular Weight; Rabbits; Sodium Dodecyl Sulfate; Tryptophan; Ultracentrifugation | 1972 |
Biosynthesis of echinulin. Isoprenylation of cyclo-L-alanyl-L-tryptophanyl.
Topics: Alanine; Allyl Compounds; Ammonium Sulfate; Aspergillus; Carbon Isotopes; Cell-Free System; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Dipeptides; Mass Spectrometry; Phosphoric Acids; Spectrophotometry; Terpenes; Tritium; Tryptophan; Ultraviolet Rays | 1972 |
Synthesis of a linear gramicidin by a combination of biosynthetic and organic methods.
Topics: Acylation; Adenosine Triphosphate; Alanine; Amino Acid Sequence; Amino Alcohols; Aminopterin; Ammonium Sulfate; Bacillus; Carbon Isotopes; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Chromatography, Thin Layer; Diphosphates; Formates; Glycine; Leucine; Optical Rotation; Oxidation-Reduction; Peptides; Phosphorus Isotopes; Tryptophan; Tyrothricin; Valine | 1972 |
Synthesis of four undecanucleotides complementary to a region of the coat protein cistron of phage fd.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Base Sequence; Coliphages; DNA Nucleotidyltransferases; DNA Repair; DNA, Single-Stranded; DNA, Viral; Genetic Code; Genetics, Microbial; Methionine; Nucleic Acid Hybridization; Oligonucleotides; Phosphoric Diester Hydrolases; Polynucleotides; Snakes; Spectrophotometry, Ultraviolet; Spleen; Tryptophan; Valine; Venoms; Viral Proteins | 1973 |
Bradykinin potentiating peptide PCA-Lys-Trp-Ala-Pro. An inhibitor of the pulmonary inactivation of bradykinin and conversion of angiotensin I to II.
Topics: Alanine; Alcohols; Angiotensin II; Animals; Benzyl Compounds; Biological Assay; Blood Pressure; Bradykinin; Capillary Permeability; Carboxylic Acids; Cats; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Countercurrent Distribution; Dogs; Drug Synergism; Formates; Glutamates; Guinea Pigs; Ileum; In Vitro Techniques; Ion Exchange Resins; Lung; Lysine; Male; Peptides; Proline; Pyrrolidinones; Rabbits; Rats; Snakes; Time Factors; Tryptophan; Venoms | 1971 |
Interaction of apolipoprotein-alamine and apolipoprotein-glutamine-I with phosphatidylcholine. Effect on solute quenching of intrinsic fluorescence.
Topics: Alanine; Apoproteins; Chlorine; Eggs; Glutamine; Humans; Iodides; Lipoproteins; Lipoproteins, HDL; Lipoproteins, VLDL; Phosphatidylcholines; Protein Binding; Pyridinium Compounds; Serum Albumin; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan | 1974 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Structure of the major complex formed by interaction of phosphatidylcholine bilamellar vesicles and apolipoprotein-alanine (APO-C-III).
Topics: Alanine; Apoproteins; Binding Sites; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Circular Dichroism; Humans; Light; Lipoproteins, VLDL; Mathematics; Membranes, Artificial; Microscopy, Electron; Molecular Conformation; Phosphatidylcholines; Protein Binding; Protein Conformation; Scattering, Radiation; Spectrometry, Fluorescence; Tryptophan; Ultracentrifugation; Ultrafiltration | 1974 |
On the neurotoxic effects induced by alkylating agents.
Topics: Alanine; Animals; Anti-Bacterial Agents; Antimetabolites; Azaserine; Behavior, Animal; Central Nervous System; Chlorambucil; Cyclophosphamide; Cysteine; Drug Antagonism; Glycine; Male; Mannitol; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Phenobarbital; Phenytoin; Rats; Seizures; Spasm; Thiourea; Triethylenemelamine; Tryptophan | 1966 |
Bacillus subtilis glutamine synthetase. Dependence of -glutamyltransferase activity on ionic strength and specific monovalent cations.
Topics: Adenosine Monophosphate; Alanine; Arsenic; Bacillus subtilis; Catalysis; Enzyme Activation; Feedback; Glutamate-Ammonia Ligase; Glycine; Hydroxylamines; Lithium; Macromolecular Substances; Magnesium; Manganese; Naphthalenes; Osmolar Concentration; Potassium; Rubidium; Scattering, Radiation; Sodium; Spectrometry, Fluorescence; Sulfonic Acids; Tryptophan; Ultracentrifugation | 1972 |
Effects of cobaltous ion on various catalytic parameters and on heterologous subunit interactions of Escherichia coli glutamine synthetase.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Catalysis; Cobalt; Colorimetry; Cytosine Nucleotides; Enzyme Activation; Escherichia coli; Feedback; Glutamate-Ammonia Ligase; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Macromolecular Substances; Magnesium; Manganese; Models, Structural; Quaternary Ammonium Compounds; Tryptophan | 1972 |
Lipolytic and hypoglycemic compounds obtained from cystoseira barbata J. Ag.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Blood Glucose; Chromatography, Gel; Chromatography, Paper; Eukaryota; Glutamine; Histidine; Leucine; Lipid Metabolism; Lysine; Methionine; Peptide Fragments; Rabbits; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Kinetic properties of pyruvate kinases from turtle liver and heart.
Topics: Alanine; Allosteric Regulation; Animals; Binding Sites; Citrates; Cysteine; Enzyme Activation; Fructosephosphates; Hexosediphosphates; Hydrogen-Ion Concentration; Isoleucine; Ketoglutaric Acids; Kinetics; Liver; Magnesium; Methionine; Myocardium; Organ Specificity; Phenylalanine; Phosphoenolpyruvate; Protein Binding; Pyruvate Kinase; Serine; Succinates; Tryptophan; Turtles; Valine | 1974 |
The effect of tryptophan administration on fatty acid synthesis in the liver of the fasted normal rat.
Topics: Acetates; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Animals; Carbon Radioisotopes; Cholesterol; Chromatography, Thin Layer; Citric Acid Cycle; Fasting; Fatty Acids; Fatty Acids, Nonesterified; Glycerol; Intestine, Small; Lipids; Liver; Male; Phospholipids; Pyruvate Dehydrogenase Complex; Quinolines; Rats; Time Factors; Triglycerides; Tritium; Tryptophan; Water | 1974 |
Composition of the rhodopsin-core obtained by proteolysis of retinal rod outer segments with papain, and its regenerability after photobleaching.
Topics: Alanine; Animals; Arginine; Carbohydrates; Cattle; Chromatography, Thin Layer; Electrophoresis; Glutamates; Glycine; Histidine; Leucine; Light; Lysine; Papain; Photoreceptor Cells; Retinal Pigments; Retinaldehyde; Rhodopsin; Threonine; Tryptophan; Tyrosine | 1974 |
Plasma concentrations of tryptophan and other amino acids in manic-depressive patients.
Topics: Alanine; Arginine; Aspartic Acid; Bipolar Disorder; Emotions; Glutamates; Glycine; Humans; Isoleucine; Leucine; Methionine; Psychology; Serine; Threonine; Tryptophan; Tyrosine | 1974 |
[Amino acid levels in the blood serum of patients with chronic colitis].
Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Betaine; Chronic Disease; Citrulline; Colitis; Glutamates; Glutamine; Glycine; Histidine; Humans; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tryptophan; Tyrosine; Urea | 1974 |
Free amino acid levels in the boll weevil (Coleoptera: Curculionidae): the effect of five different diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography, Gas; Coleoptera; Diet; Dietary Proteins; Glutamates; Glycine; Gossypium; Histidine; Isoleucine; Leucine; Male; Mass Spectrometry; Methionine; Phenylalanine; Proline; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Navy (Haricot)-bean (Phaseolus vulgaris) lectin. Isolation and characterization of tow components from a toxic agglutinating extract.
Topics: Alanine; Animals; Aspartic Acid; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cysteine; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Glucosamine; Glycoproteins; Hemagglutination Tests; Horses; Lectins; Leucine; Leukocytes; Mannose; Methionine; Molecular Weight; Plant Lectins; Plants; Quail; Serine; Tryptophan | 1974 |
Analysis of isoaccepting tRNAs during the growth phase mitotic cycle of Physarum polycephalum.
Topics: Alanine; Amino Acids; Amino Acyl-tRNA Synthetases; Asparagine; Cell Division; Chromatography, Ion Exchange; Codon; Genetic Code; Glycine; Histidine; Isoleucine; Leucine; Mitosis; Myxomycetes; Protein Biosynthesis; RNA, Transfer; Tritium; Tryptophan; Valine | 1974 |
Intestinal absorption of stereoisomers of dipeptides in the rat.
Topics: Alanine; Aldehydes; Animals; Biological Transport; Diffusion; Dipeptides; Glycine; Hydrolysis; Ileum; Indoleacetic Acids; Indoles; Intestinal Absorption; Intestinal Mucosa; Jejunum; Leucine; Liver; Male; Molecular Weight; Peptide Hydrolases; Phenylalanine; Rats; Stereoisomerism; Tryptophan | 1973 |
50-S ribosomal proteins. Purification and partial characterization of two acidic proteins, A 1 and A 2, isolated from 50-S ribosomes of Escherichia coli.
Topics: Alanine; Amino Acids; Autoanalysis; Bacterial Proteins; Chromatography, DEAE-Cellulose; Cysteine; Electrophoresis; Escherichia coli; Histidine; Isoelectric Focusing; Molecular Weight; Ribosomes; Sodium Dodecyl Sulfate; Tryptophan; Tyrosine; Ultracentrifugation | 1972 |
Chemistry and subunit structure of yeast hexokinase isoenzymes.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Carboxypeptidases; Electrophoresis, Polyacrylamide Gel; Hexokinase; Isoenzymes; Molecular Weight; Oxidation-Reduction; Peptide Fragments; Peptide Hydrolases; Saccharomyces cerevisiae; Sodium Dodecyl Sulfate; Spectrophotometry, Ultraviolet; Tryptophan; Ultracentrifugation; Valine | 1973 |
Nucleotide sequences of transfer ribonucleic acids.
Topics: Alanine; Arginine; Aspartic Acid; Base Sequence; Biological Evolution; Escherichia coli; Evaluation Studies as Topic; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Plants; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Serine; Species Specificity; Tryptophan; Tyrosine; Valine | 1974 |
Basis of transport discrimination of arginine from other basic amino acids in Salmonella typhimurium.
Topics: Alanine; Amino Acids; Arginine; Autoanalysis; Biological Transport; Carbon Radioisotopes; Chromatography, Ion Exchange; Deuterium; Glucose; Histidine; Homoserine; Hydroxyproline; Kinetics; Leucine; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Ornithine; Proline; Salmonella typhimurium; Structure-Activity Relationship; Tritium; Tryptophan | 1974 |
The functional significance of the evolutionary divergence between the tryptophan operons of Escherichia coli and Salmonella typhimurium.
Topics: Alanine; Biological Evolution; Drug Resistance, Microbial; Escherichia coli; Genetic Variation; Glycerophosphates; Indole-3-Glycerol-Phosphate Synthase; Operon; ortho-Aminobenzoates; p-Fluorophenylalanine; Plasmids; Ribulosephosphates; Salmonella typhimurium; Species Specificity; Tryptophan; Tryptophan Synthase | 1974 |
Significance of altered carbon flow in aromatic amino acid synthesis: an approach to the isolation of regulatory mutants in Pseudomonas aeruginosa.
Topics: Alanine; Amino Acids; Biological Assay; Carbon; Cell-Free System; Culture Media; Cyclohexanecarboxylic Acids; Drug Resistance, Microbial; Fluorine; Fluorometry; Fructose; Genetics, Microbial; Hydro-Lyases; Leuconostoc; Methods; Mutation; ortho-Aminobenzoates; Pentosyltransferases; Phenylalanine; Pseudomonas aeruginosa; Transaminases; Tryptophan; Tyrosine | 1972 |
Exogenous carbon and nitrogen requirements for conidial germination by Aspergillus flavus.
Topics: Alanine; Amino Acids; Ammonium Chloride; Aspergillus; Aspergillus flavus; Carbon; Carbon Dioxide; Culture Media; Glucose; Glycine; Nitrogen; Proline; Spores; Spores, Fungal; Surface-Active Agents; Tryptophan | 1972 |
[Amino acids in parenteral feeding].
Topics: Alanine; Amino Acids; Arginine; Histidine; Homeostasis; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Nutrition Disorders; Parenteral Nutrition; Phenylalanine; Proline; Protein Conformation; Protein-Energy Malnutrition; Proteins; Threonine; Tryptophan; Valine | 1972 |
Transformation of germinated spores of Bacillus subtilis on agar plates.
Topics: Agar; Alanine; Bacillus subtilis; Carbon Isotopes; Culture Media; DNA Replication; DNA, Bacterial; Spores, Bacterial; Transformation, Genetic; Tryptophan | 1973 |
Amino acid metabolism in chameleon liver.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Citrulline; Female; Glutamates; Glutamine; Glycine; Histidine; Keto Acids; Liver; Lizards; Lysine; Male; Methionine; Ornithine; Phenylalanine; Pyruvates; Serine; Threonine; Tryptophan | 1972 |
[Amino acid metabolism pathology in the convulsive syndrome in young children].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Child, Preschool; Cystine; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Infant; Infant, Newborn; Leucine; Lysine; Male; Methionine; Proline; Seizures; Serine; Tryptophan; Tyrosine; Valine | 1972 |
[Effect of certain amino acids on the thermostability of animal and plant cells and cellular models].
Topics: Alanine; Amino Acids; Animals; Anura; Chromatography, Paper; Electrophoresis, Paper; Epithelial Cells; Epithelium; Glycerol; Glycine; In Vitro Techniques; Magnoliopsida; Models, Biological; Oviducts; Protein Denaturation; Ranidae; Serine; Thermosensing; Tryptophan | 1972 |
Zymogen-enzyme transformations. On the mechanism of activation of prophospholipase A.
Topics: Alanine; Aminopeptidases; Animals; Binding Sites; Calcium; Enzyme Activation; Enzyme Precursors; Kinetics; Optical Rotatory Dispersion; Pancreas; Phosphatidylcholines; Phospholipases; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Swine; Trypsin; Tryptophan | 1972 |
Release of cholecystokinin by amino acids.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Bicarbonates; Cholecystokinin; Cysteine; Dogs; Drug Synergism; Duodenum; Glutamates; Glycine; Intestinal Mucosa; Pancreas; Pancreatic Juice; Perfusion; Phenylalanine; Secretin; Threonine; Tryptophan | 1973 |
Exchange transport between various amino acids and alanine in isolated intestinal epithelial cells.
Topics: Alanine; Amino Acids; Animals; Arginine; Biological Transport; Carbon Isotopes; Epithelial Cells; Epithelium; Histidine; Intestinal Mucosa; Intestines; Isoleucine; Leucine; Lysine; Male; Ornithine; Phenylalanine; Rats; Sodium; Threonine; Time Factors; Tryptophan; Valine | 1973 |
Biosynthesis of ergotamine by Claviceps purpurea (Fr.) Tul.
Topics: Acetates; Alanine; Amino Acids; Carbon Isotopes; Cells, Cultured; Chromatography, Ion Exchange; Chromatography, Thin Layer; Culture Media; Electrophoresis, Paper; Ergotamine; Formates; Hydrogen-Ion Concentration; Isomerism; Methionine; Mevalonic Acid; Phenylalanine; Plants; Proline; Spectrophotometry, Ultraviolet; Tryptophan | 1973 |
Amino acid metabolism in chameleon tissues.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brain; Citrulline; Glutamates; Glutamine; Glycine; Histidine; Ketoglutaric Acids; Kidney; Liver; Lysine; Muscles; Myocardium; Ornithine; Oxaloacetates; Proline; Pyruvates; Reptiles; Serine; Tryptophan | 1973 |
Quenching of tryptophan fluorescence in rabbit and bovine IgG.
Topics: Alanine; Amino Acids; Ammonium Sulfate; Animals; Autoanalysis; Cattle; Chemical Precipitation; Fluorescence; Hydrogen-Ion Concentration; Immune Sera; Immunoglobulin Fab Fragments; Immunoglobulin G; Rabbits; Tryptophan | 1973 |
The metabolism of amino acids in the bovine lens. Their oxidation as a source of energy.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Carbon Dioxide; Carbon Radioisotopes; Cattle; Collagen; Energy Metabolism; Glucose; Glutamates; Glutathione; In Vitro Techniques; Lactates; Lens, Crystalline; Leucine; Lipid Metabolism; Lysine; Oxidation-Reduction; Proline; Serine; Taurine; Tryptophan; Tyrosine | 1973 |
Plasma amino acids in experimental acute hepatic failure and their relationship to brain tryptophan.
Topics: Acute Disease; Alanine; Amino Acids; Animals; Brain Chemistry; Disease Models, Animal; Glycine; Hepatic Encephalopathy; Liver Diseases; Methionine; Swine; Tryptophan | 1974 |
Amino acid uptake into human brain tumors.
Topics: Absorption; Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Astrocytoma; Autoradiography; Brain Neoplasms; Chloromercuribenzoates; Culture Techniques; Cyanides; Ependymoma; Glutamates; Glycine; Humans; Lysine; Ouabain; Phenylalanine; Taurine; Time Factors; Tritium; Tryptophan; Valine | 1974 |
The synthesis of oligopeptidyl-tRNA.
Topics: Alanine; Binding Sites; Carbon Radioisotopes; Evaluation Studies as Topic; Glycine; Methods; Nitrophenols; Oligopeptides; RNA, Transfer; Succinates; Tryptophan; Tyrosine; Valine | 1974 |
Interactions of aromatic residues of proteins with nucleic acids. I. Proton magnetic resonance studies of the binding of tryptophan-containing peptides to poly(adenylic acid) and deoxyribonucleic acid.
Topics: Adenine Nucleotides; Alanine; Animals; Binding Sites; Cattle; Cold Temperature; Deuterium; DNA; Glycine; Hydrogen-Ion Concentration; Indoles; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Methyl Ethers; Nucleic Acid Conformation; Oligopeptides; Osmolar Concentration; Polynucleotides; Protons; Serotonin; Sodium Chloride; Structure-Activity Relationship; Thymus Gland; Tryptamines; Tryptophan | 1974 |
Regulation of glutamine synthetase. 3. Cumulative feedback inhibition of glutamine synthetase from Escherichia coli.
Topics: Adenine Nucleotides; Alanine; Carbamates; Cytosine Nucleotides; Escherichia coli; Feedback; Glucosamine; Glutamine; Glycine; Histidine; Kinetics; Ligases; Magnesium; Manganese; Phosphates; Tryptophan | 1967 |
Regulation of glutamine synthetase. X. Effect of growth conditions on the susceptibility of Escherichia coli glutamine synthetase to feedback inhibition.
Topics: Adenine Nucleotides; Alanine; Ammonium Chloride; Calcium; Cobalt; Culture Media; Cytosine Nucleotides; Escherichia coli; Feedback; Glucose; Glutamates; Glutamine; Glycerol; Glycine; Histidine; Leucine; Ligases; Magnesium; Manganese; Nitrites; Oxygen; Tryptophan | 1967 |
sRNA specificity for codon recognition as studied by the ribosomal binding technique.
Topics: Alanine; Arginine; Chromatography; Countercurrent Distribution; Escherichia coli; Genetic Code; Glycine; Isoleucine; Leucine; Methionine; Phenylalanine; Polynucleotides; Ribosomes; RNA, Transfer; Serine; Tryptophan; Valine; Yeasts | 1966 |
A comparison of the rates of RNA and protein synthesis in Escherichia coli cells partially starved for different amino acids.
Topics: Alanine; Amino Acids; Bacterial Proteins; Butyrates; Depression, Chemical; Escherichia coli; Feedback; Histidine; Keto Acids; Ribosomes; RNA, Bacterial; Thiazoles; Time Factors; Tryptophan | 1968 |
Amino acid transport systems in Escherichia coli K-12.
Topics: Alanine; Amino Acids; Azides; Biological Transport; Calcium; Carbon Isotopes; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Kinetics; Leucine; Methionine; Phenylalanine; Serine; Sodium; Temperature; Tryptophan; Tyrosine; Valine | 1968 |
Conformational changes in glutamine synthetase from Escherichia coli. II. Some characteristics of the equilibrium binding of feedback inhibitors to the enzyme.
Topics: Adenine Nucleotides; Alanine; Ammonia; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Dialysis; Escherichia coli; Feedback; Glutamine; Kinetics; Ligases; Magnesium; Manganese; Phosphorus Isotopes; Protein Binding; Thermodynamics; Tryptophan | 1969 |
Localization of acyl carrier protein in Escherichia coli.
Topics: Alanine; Autoradiography; Bacterial Proteins; Cytoplasm; Escherichia coli; Fatty Acids; Glutamates; Microscopy, Electron; Thymidine; Tritium; Tryptophan | 1970 |
The primary structure of transfer ribonucleic acid.
Topics: Alanine; Aspartic Acid; Cryptococcus; Escherichia coli; Genetic Code; Isoleucine; Leucine; Methionine; Methylation; Nucleotides; Phenylalanine; RNA, Transfer; Saccharomyces; Serine; Tryptophan; Tyrosine; Valine | 1971 |
In vivo assay of protein synthesizing capacity of Escherichia coli from slowly growing chemostat cultures.
Topics: Alanine; Amino Acids; Bacterial Proteins; Carbon; Carbon Isotopes; Escherichia coli; Glucose; Guanine; Kinetics; RNA, Bacterial; Sulfates; Tryptophan; Vitamins | 1971 |
Analysis of amino acid replacements resulting from frameshift and missense mutations in the tryptophan synthetase A gene of Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Asparagine; Aspartic Acid; Escherichia coli; Genetic Code; Glycine; Ligases; Mutation; Peptides; Suppression, Genetic; Tryptophan; Valine | 1968 |
The B protein of Escherichia coli tryptophan synthetase. II. New -elimination and -replacement reactions.
Topics: Alanine; Carbon Isotopes; Chemical Phenomena; Chemistry; Chlorine; Cysteine; Escherichia coli; Ethers; Glycerophosphates; Hydro-Lyases; Indoles; Kinetics; Mercaptoethanol; Methanol; Models, Biological; Serine; Sulfhydryl Compounds; Sulfides; Tryptophan | 1971 |
Amino-acid protection of ultra-violet-irradiated Bacillus subtilis.
Topics: Acid-Base Equilibrium; Alanine; Bacillus subtilis; Culture Media; Glycine; Histidine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays | 1966 |
Autotrophic and heterotrophic metabolism of Hydrogenomonas. I. Growth yields and patterns under dual substrate conditions.
Topics: Acetates; Alanine; Amino Acids; Biological Assay; Histidine; Hydrogen; Lactobacillus; Mutation; Pseudomonas; Tryptophan | 1968 |
[Effects of various amino acids on the sensitivity of 11 strains of Staphylococcus aureus to penicillin G].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Glycine; Isoleucine; Leucine; Methionine; Penicillin G; Penicillin Resistance; Staphylococcus; Stereoisomerism; Tryptophan; Valine | 1969 |
Formation and localization of the alkaline phosphatase of Escherichia coli.
Topics: Alanine; Alkaline Phosphatase; Amino Acids; Antigen-Antibody Reactions; Binding Sites; Carbon Isotopes; Cross Reactions; Cytoplasm; Dialysis; Enzyme Repression; Escherichia coli; Histidine; Immunodiffusion; Molecular Weight; Mutation; Phosphates; Phosphotransferases; Protoplasts; Tryptophan; Zinc; Zinc Isotopes | 1969 |
Some kinetic properties of Bacillus subtilis glutamine synthetase.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Alanine; Ammonia; Bacillus subtilis; Cytosine Nucleotides; Drug Synergism; Enzyme Activation; Escherichia coli; Feedback; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Iron; Kinetics; Ligases; Magnesium; Manganese; Temperature; Tryptophan | 1970 |
Proflavine binding and release by sensitive and resistant Bacillus subtilis.
Topics: Acridines; Alanine; Bacillus subtilis; Drug Resistance, Microbial; Glucose; Glycerol; Protein Binding; Sodium; Sodium Chloride; Sucrose; Temperature; Time Factors; Tryptophan | 1970 |
The inhibition of intestinal absorption of phenylalanine in the rhesus monkey.
Topics: Alanine; Animals; Diet; Haplorhini; Intestinal Absorption; Leucine; Male; Phenylalanine; Tryptophan; Tyrosine | 1970 |
[Nitrogen metabolism in parenteral feeding].
Topics: Adult; Aged; Alanine; Amino Acids; Ammonia; Creatinine; Diet Therapy; Duodenal Ulcer; Female; Glycine; Humans; Male; Methionine; Middle Aged; Nitrogen; Parenteral Nutrition; Proline; Serine; Stomach Ulcer; Tryptophan; Urea | 1971 |
Structural proteins of adenoviruses. VII. Purification and properties of an arginine-rich core protein from adenovirus type 2 and type 3.
Topics: Adenoviridae; Alanine; Amino Acids; Animals; Antigens; Arginine; Autoanalysis; Carcinoma; Cell Line; Chromatography, Thin Layer; Complement Fixation Tests; Cricetinae; Electrophoresis, Disc; Fluorometry; Immune Sera; Immunodiffusion; Molecular Weight; Mouth Neoplasms; Rabbits; Serotyping; Spectrophotometry; Sulfur Isotopes; Tritium; Tryptophan; Tyrosine; Ultracentrifugation; Ultraviolet Rays; Viral Proteins; Virus Cultivation | 1971 |
Properties and subunit structure of the B component of Pseudomonas putida tryptophan synthetase.
Topics: Alanine; Amino Acids; Borohydrides; Carboxypeptidases; Catalysis; Chemical Precipitation; Chromatography, Gel; Cross Reactions; Detergents; Drug Stability; Electrophoresis, Disc; Escherichia coli; Formates; Glycerophosphates; Hot Temperature; Hydro-Lyases; Immune Sera; Immunodiffusion; Indoles; Kinetics; Macromolecular Substances; Mercaptoethanol; Molecular Weight; Oxidation-Reduction; Pseudomonas; Pyridoxal Phosphate; Serine; Spectrophotometry; Sulfuric Acids; Tryptophan; Ultracentrifugation; Urea | 1971 |
Specificity of Aeromonas aminopeptidase toward amino acid amides and dipeptides.
Topics: Aeromonas; Alanine; Amides; Amino Acids; Aminocaproates; Aminopeptidases; Dipeptides; Glycine; Isoleucine; Kinetics; Leucine; Methionine; Phenylalanine; Structure-Activity Relationship; Tryptophan; Tyrosine; Valerates; Valine | 1972 |
Specificity in enzyme inhibition. 2. -Aminohydroxamic acids as inhibitors of histidine decarboxylase and 3,4-dihydroxyphenylalanine decarboxylase.
Topics: Alanine; Amino Acids; Aromatic Amino Acid Decarboxylase Inhibitors; Binding Sites; Carboxy-Lyases; Drug Antagonism; Histidine; Hydroxamic Acids; Imidazoles; Models, Chemical; Phenylalanine; Structure-Activity Relationship; Tryptophan; Tyrosine | 1972 |
Specificity and spectral resolution of an L-glutamate dehydrogenase-monocarboxylic amino acid complex.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminocaproates; Binding Sites; Glutamate Dehydrogenase; Isoleucine; Leucine; Methionine; Protein Binding; Spectrophotometry; Structure-Activity Relationship; Tryptophan; Tyrosine; Ultraviolet Rays; Valine | 1972 |
A basis for the difference in the inhibition of the uptake of various neutral amino acids by lysine in intestinal epithelial cells.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Carbon Isotopes; Epithelial Cells; Epithelium; Histidine; Intestinal Mucosa; Intestines; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Rats; Sodium; Threonine; Tryptophan; Valine | 1972 |
A comparison of the utilization of methyl and p-nitrophenyl esters in determining the specificity of -chymotrypsin.
Topics: Acetates; Alanine; Catalysis; Chymotrypsin; Glycine; Hydrolysis; Kinetics; Leucine; Methanol; Nitrophenols; Phenylalanine; Stereoisomerism; Structure-Activity Relationship; Tryptophan; Valine | 1972 |
Influence of nutrition on the morphology of a strain of Bifidobacterium bifidum.
Topics: Acetates; Alanine; Amino Acids; Asparagine; Aspartic Acid; Culture Media; Cysteine; Glutamates; Lactobacillus; Mutation; Nutritional Physiological Phenomena; Quaternary Ammonium Compounds; Serine; Surface-Active Agents; Tryptophan | 1972 |
Selective free radical reactions with proteins and enzymes: reactions of inorganic radical anions with amino acids.
Topics: Alanine; Amino Acids; Bromides; Carbonates; Chlorides; Cysteine; Free Radicals; Histidine; Hydrogen-Ion Concentration; Iodides; Kinetics; Methionine; Muramidase; Proteins; Radiation Effects; Radiochemistry; Spectrophotometry; Thiocyanates; Tryptophan; Tyrosine | 1972 |
Hepatic gluconeogenesis and glycogenesis in the starved, x-irradiated rat.
Topics: Alanine; Animals; Blood Glucose; Body Weight; Carbon Isotopes; Fasting; Gluconeogenesis; Glucose; Liver; Liver Glycogen; Male; Quinolines; Radiation Effects; Rats; Rats, Inbred Strains; Statistics as Topic; Time Factors; Tryptophan | 1972 |
[Metabolic and catalytic functions of vitamin B6].
Topics: Alanine; Apoproteins; Catalysis; Chemical Phenomena; Chemistry; Enzyme Activation; Pyridoxal Phosphate; Pyridoxine; Tryptophan | 1972 |
Ribonuclease of Chalaropsis species. II. Chemical properties.
Topics: Alanine; Alkylation; Amides; Amino Acid Sequence; Amino Acids; Ammonia; Aspergillus; Autoanalysis; Carbon Isotopes; Computers; Disulfides; Formates; Glycine; Iodoacetates; Mitosporic Fungi; Oxidation-Reduction; Peptides; Ribonucleases; Species Specificity; Thiocyanates; Tryptophan | 1972 |
Influx of neutral amino acids across the brush border of rabbit ileum. Stereospecificity and the roles of the -amino and -carboxylate groups.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Chemical Phenomena; Chemistry; Diffusion; Female; Histidine; Ileum; Intestinal Mucosa; Kinetics; Leucine; Male; Phenylalanine; Rabbits; Serine; Sodium; Stereoisomerism; Structure-Activity Relationship; Tryptophan; Valine | 1972 |
[Beef brain alkaline phosphatase: role of magnesium on the action of L-phenylalanine and other amino acids].
Topics: Alanine; Alkaline Phosphatase; Amino Acids; Aminocaproates; Animals; Binding Sites; Brain; Cattle; Chemical Phenomena; Chemistry; Enzyme Activation; Female; Humans; Hydrogen-Ion Concentration; Intestines; Isoleucine; Kinetics; Leucine; Magnesium; Molecular Weight; Phenylalanine; Placenta; Pregnancy; Serine; Stereoisomerism; Tryptophan | 1971 |
The difference between alpha-and delta-chymotrypsins. Preparation and alkaline pH dependence of alpha1-chymotrypsin-catalyzed hydrolysis of N-acetyl-L-tryptophan methyl ester (ATME). The involement of alanine-149 in alpha-chymotrypsin catalysis.
Topics: Acetates; Alanine; Catalysis; Chemical Phenomena; Chemistry; Chymotrypsin; Esters; Hydrogen-Ion Concentration; Hydrolysis; Tryptophan | 1971 |
Transamination of amino acids in homogenates of rat brzain.
Topics: Age Factors; Alanine; Amino Acids; Animals; Animals, Newborn; Asparagine; Aspartic Acid; Brain; Chromatography; Culture Media; Electrophoresis, Paper; Glutamates; Glutamine; Isoleucine; Ketoglutaric Acids; Male; Methionine; Organ Culture Techniques; Ornithine; Phenylalanine; Pyruvates; Rats; Transaminases; Tryptophan; Tyrosine; Valine | 1971 |
Effect of excess levels of individual amino acids on growth of rats fed casein diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Caseins; Cystine; Depression, Chemical; Dietary Proteins; DNA; Glutamates; Glycine; Growth; Histidine; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Organ Size; Phenylalanine; Proline; Proteins; Rats; RNA; Serine; Stereoisomerism; Stimulation, Chemical; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Daily variations in the concentrations of individual amino acids in rat plasma.
Topics: Alanine; Amino Acids; Animals; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Phenylalanine; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Optical rotatory dispersion and circular dichroism of mono- and oligonucleotide-amino acids (amidates).
Topics: Adenine Nucleotides; Alanine; Amines; Amino Acids; Chemical Phenomena; Chemistry; Chromatography, Paper; Circular Dichroism; Cytosine Nucleotides; Deoxyribonucleotides; Electrophoresis, Paper; Guanine Nucleotides; Inosine Nucleotides; Methylamines; Models, Structural; Nucleotides; Optical Rotatory Dispersion; Phenylalanine; Polynucleotides; Thymine Nucleotides; Tryptophan; Tyrosine; Ultraviolet Rays; Uracil Nucleotides | 1971 |
Reaction of 2-hydroxy-5-nitrobenzylated carboxypeptidase A with 14 C-1-fluoro-2,4-dinitrobenzene.
Topics: Alanine; Alkylation; Amino Acids; Aspartic Acid; Benzyl Compounds; Carbon Isotopes; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Thin Layer; Dinitrophenols; Fluorine; Fluorometry; Guanidines; Hydrolysis; Nitrobenzenes; Nitrophenols; Protein Denaturation; Serine; Spectrophotometry; Tryptophan; Ultraviolet Rays | 1971 |
The effect of dietary fluoride on plasma free amino acid concentrations in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Diet; Feeding Behavior; Female; Fluorides; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Rats, Inbred Strains; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Studies on the biosynthesis of mitomycin C by Streptomyces verticillatus.
Topics: Acetamides; Acetates; Alanine; Anhydrides; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Formates; Glucose; Glycine; Heptoses; Isoleucine; Leucine; Methionine; Mevalonic Acid; Mitomycins; Models, Biological; Models, Structural; Oxidation-Reduction; Pentosephosphates; Phenylalanine; Serine; Shikimic Acid; Sodium; Spectrophotometry; Streptomyces; Tryptophan; Valine | 1971 |
Nitrogen balance of men fed amino acid mixtures based on Rose's requirements, egg white protein, and serum free amino acid patterns.
Topics: Adult; Alanine; Amino Acids; Dietary Proteins; Dietetics; Feces; Glutamates; Glycine; Histidine; Humans; Male; Methods; Nitrogen; Nutritional Requirements; Ovalbumin; Protein Deficiency; Statistics as Topic; Tryptophan | 1971 |
Stimulation of basic amino acid uptake by certain neutral amino acids in isolated intestinal epithelial cells.
Topics: Alanine; Animals; Arginine; Biological Transport; Biological Transport, Active; Carbon Isotopes; Depression, Chemical; Epithelial Cells; Epithelium; Glycine; Histidine; Hydrochloric Acid; Intestinal Mucosa; Intestines; Inulin; Isoleucine; Kinetics; Leucine; Lysine; Male; Mathematics; Methionine; Ornithine; Phenylalanine; Proline; Rats; Rats, Inbred Strains; Serous Membrane; Sodium; Stimulation, Chemical; Tritium; Tryptophan; Valine | 1971 |
[Dissociation of S- and P-variants of Bacillus brevis var. G.-B. on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Mutation; Nitrogen; Ornithine; Phenylalanine; Serine; Stimulation, Chemical; Threonine; Time Factors; Tryptophan; Valine | 1971 |
Changes in conformation of insolubilized trypsin and chymotrypsin, followed by fluorescence.
Topics: Alanine; Binding Sites; Carboxylic Acids; Chymotrypsin; Cyanogen Bromide; Hot Temperature; Hydrogen-Ion Concentration; Mathematics; Naphthalenes; Peptides; Polysaccharides; Protein Binding; Protein Conformation; Protein Denaturation; Solubility; Spectrometry, Fluorescence; Sulfonic Acids; Temperature; Toluidines; Trypsin; Trypsin Inhibitors; Tryptophan; Urea | 1971 |
Use of chemical ionization mass spectrometry in analysis of amino acid phenylthiohydantoin derivatives formed during Edman degradation of proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Cetacea; Chromatography, Gas; Deuterium; Glutamine; Glycine; Hydantoins; Leucine; Mass Spectrometry; Methods; Myoglobin; Sulfides; Tryptophan; Valine | 1971 |
[Studies on the correlations between presence of free amino acids in the saliva and dental caries].
Topics: Alanine; Amino Acids; Chemistry Techniques, Analytical; Dental Caries Susceptibility; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Phenylalanine; Saliva; Tryptophan | 1968 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
The growth-stimulating activity of peptides on human hematopoietic cell cultures.
Topics: Alanine; Amino Acids; Cell Division; Cell Line; Culture Media; Culture Techniques; Dipeptides; Growth Substances; Hematopoiesis; Humans; Kinetics; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocytes; Peptides; Phenylalanine; Tryptophan; Tyrosine; Valine | 1969 |
Isoaccepting transfer RNA's of L-M cells in culture and after tumor induction in C3H mice.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cell Line; Chromatography; Connective Tissue; Culture Media; Culture Techniques; Female; Fibrosarcoma; Glycine; Histidine; Isoleucine; Leucine; Ligases; Lysine; Male; Methionine; Mice; Phenylalanine; Proline; RNA, Transfer; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
X- and gamma-radiolysis of some tryptophan dipeptides.
Topics: Alanine; Chromatography, Thin Layer; Glycine; Leucine; Models, Chemical; Peptides; Phenylalanine; Radiation Effects; Tryptophan; Tyrosine | 1970 |
Amino acid replacements associated with reversion and recombination within a coding unit.
Topics: Alanine; Amino Acids; Aspartic Acid; Cysteine; Escherichia coli; Genetic Code; Genetics; Glycine; In Vitro Techniques; Isoleucine; Ligases; Lysine; Mutation; Peptides; Serine; Tryptophan; Valine | 1965 |
Peptide chain initiation and growth in the induced synthesis of beta-galactosidase.
Topics: Alanine; Chloramphenicol; Enzyme Induction; Escherichia coli; Galactosidases; Hydroxylamines; Peptide Biosynthesis; RNA, Messenger; Thiophenes; Tryptophan | 1966 |
Beta-pyrrolo-L-alanine, a new antimetabolite of phenylalanine and tyrosine in Escherichia coli.
Topics: Alanine; Antimetabolites; Chemistry, Organic; Escherichia coli; Organic Chemistry Phenomena; Phenylalanine; Pyrroles; Tryptophan; Tyrosine | 1966 |
Electrochemical studies on the adsorption of amino acids in relation to the compatibility of prosthetic materials and the human body.
Topics: Adsorption; Alanine; Amino Acids; Arginine; Computers; Electrochemistry; Histidine; Hydroxyproline; Lysine; Phenylalanine; Proline; Prostheses and Implants; Surface Tension; Tryptophan; Tyrosine | 1969 |
Effect of cholesteryl 14-methylhexadecanoate on the activity of some amino acid-transfer ribonucleic acid ligases from mammalian tissues.
Topics: Alanine; Animals; Carbon Isotopes; Ligases; Liver; Pancreas; Rats; RNA, Transfer; Sterols; Threonine; Tritium; Tryptophan; Tyrosine | 1969 |
Transaminase activity in sheep rumen content.
Topics: Alanine; Alanine Transaminase; Animals; Arginine; Aspartic Acid; Cysteine; Eukaryota; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Leucine; Methionine; Phenylalanine; Rumen; Serine; Sheep; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
Infrared spectra of related dipeptides.
Topics: Alanine; Amides; Amines; Dipeptides; Glycine; Infrared Rays; Leucine; Spectrophotometry; Tryptophan | 1969 |
[N-(3,5-dicarboxy-4-methyl-2-pyrrolylcarbonyl) amino acids as possible substrates of prolinase].
Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry; Dipeptidases; Dipeptides; Esters; Glutamates; Glycine; Phenylalanine; Pyrroles; Tryptophan | 1970 |
An investigation of the subunit structure of yeast enolase.
Topics: Alanine; Amino Acid Sequence; Arginine; Chromatography; Cyanides; Electrophoresis, Disc; Glycerophosphates; Glycine; Histidine; Hydro-Lyases; Peptides; Spectrum Analysis; Trypsin; Tryptophan; Tyrosine; Urea; Yeasts | 1970 |
Biosynthesis of N-(alpha-hydroxyethyl) lysergamide, a metabolite of Claviceps paspali Stevens and Hall.
Topics: Acetates; Alanine; Alkaloids; Amides; Ascomycota; Carbon Isotopes; Formates; Indoles; Lactones; Mevalonic Acid; Pyruvates; Serine; Tryptophan | 1970 |
Kinetics and mechanism of oxidation-reduction reactions between pyridine nucleotides and flavins.
Topics: Alanine; Amino Acids; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavins; Hot Temperature; Hydrocarbons; Kinetics; Nucleotides; Oxidation-Reduction; Peptides; Phenylalanine; Pyridines; Tryptophan; Tyrosine | 1970 |
[Biosynthesis of gramicidin C on synthetic media with amino acids as the only N source].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Tyrothricin; Valine | 1970 |
Temperature dependence of amino acid transport in Ehrlich ascites cells: with results which bear on the A-L distinction.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Biological Transport, Active; Carcinoma, Ehrlich Tumor; Choline; Culture Media; Diffusion; Glycine; Guinea Pigs; Humans; Kinetics; Mathematics; Metabolism; Methionine; Models, Biological; Phenylalanine; Rabbits; Rats; Sodium; Temperature; Thermodynamics; Tryptophan | 1970 |
An investigation of the hyperaminoaciduria in phenylketonuria associated with the feeding of certain commercial low-phenylalanine preparations.
Topics: Alanine; Amino Acids; Child; Child, Preschool; Diet Therapy; Female; Humans; Hydro-Lyases; Infant; Male; Metabolic Diseases; Phenylalanine; Phenylketonurias; Proteins; Stereoisomerism; Tryptophan | 1970 |
Protein digestion and amino acid absorption in the cayman.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Fishes; Glutamine; Glycine; Intestinal Absorption; Lysine; Ornithine; Proteins; Reptiles; Time Factors; Tryptophan | 1970 |
Studies on plasma amino acids in East African adults in relation to endomyocardial fibrosis.
Topics: Adolescent; Adult; Alanine; Amino Acids; Arginine; Black People; Endomyocardial Fibrosis; Glycine; Histidine; Humans; Leucine; Muscle Proteins; Plants, Edible; Tryptophan; Uganda; Valine | 1970 |
The effect on the nitrogen balance of the ratio essential-non-essential amino acids in intravenously infused solutions.
Topics: Adult; Alanine; Amino Acids; Arginine; Aspartic Acid; Blood Urea Nitrogen; Female; Glycine; Histidine; Humans; Infusions, Parenteral; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Proline; Threonine; Tryptophan; Valine | 1970 |
[Effect of amino acids on the growth of Streptococcus lactis and biosynthesis of nisin].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Depression, Chemical; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Stimulation, Chemical; Streptococcus; Threonine; Tryptophan; Valine | 1970 |
Amino acid metabolism in the isolated perfused rat liver.
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Chromatography; Glutamates; Glycine; In Vitro Techniques; Liver; Lysine; Male; Methionine; Nitrogen Isotopes; Perfusion; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Urea | 1971 |
The entry of amino acids into the skeletal muscle of the rat in vivo.
Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Biological Transport; Glycine; Leucine; Muscle Proteins; Muscles; Rats; Serine; Taurine; Tryptophan | 1971 |
[Dissociation of R- and P plus-variants of Bacillus brevis var. G.-B. during growth on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Valine | 1971 |
Essential amino acids in the culture of Leishmania tarentolae.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Glucose; Glutamates; Glycine; Histidine; Leishmania; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Comparative studies on the primary structure of soluble and mitochondrial glutamic oxaloacetic transaminase isozymes. II. Amino acid sequence of the amino terminal fragments.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aminobutyrates; Animals; Aspartate Aminotransferases; Chemical Phenomena; Chemistry; Chromatography, Paper; Chymotrypsin; Cyanides; Endopeptidases; Glutamates; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Hydroxybutyrates; Isoenzymes; Mitochondria, Muscle; Myocardium; Peptides; Phenylalanine; Proline; Serine; Solubility; Swine; Thiocyanates; Tryptophan; Valine | 1971 |
Effects of morpholino-, pyrrolidino-, piperizino-, and cyclo-octyl-derivatives of beta-alanine on brain amines and amino acids.
Topics: Alanine; Amines; Amino Acids; Aminobutyrates; Animals; Blood Platelets; Brain Chemistry; Cycloparaffins; Dopamine; Female; Humans; Hydroxyindoleacetic Acid; Lysergic Acid Diethylamide; Male; Morpholines; Norepinephrine; Piperazines; Pyrrolidines; Rats; Serotonin; Tryptophan; Tyrosine | 1971 |
[Chemistry of the antibiotic A-128 (neotelomycin)--qualitative and quantitative amino acid composition].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Aspartic Acid; Chemistry Techniques, Analytical; Chromatography, Paper; Electrophoresis; Glycine; Proline; Serine; Threonine; Tryptophan | 1967 |
[Hyperaminoaciduria in children suffering from progressive muscular dystrophy].
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Arginine; Aspartic Acid; Child; Child, Preschool; Creatine; Creatinine; Female; Glutamates; Histidine; Humans; Leucine; Lysine; Male; Methionine; Muscular Dystrophies; Nitrogen; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Studies on continuous enzyme reactions. 3. Enzymatic properties of the DEAE-cellulose-aminoacylase complex.
Topics: Alanine; Amidohydrolases; Aspergillus; Cellulose; Chemical Phenomena; Chemistry; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Metals; Methionine; Phenylalanine; Protein Denaturation; Solubility; Spectrophotometry; Tryptophan; Valine | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Multivalent feedback inhibition of aspartokinase in Bacillus polymyxa. I. Effect of nonpolar L-amino acids.
Topics: Acetates; Alanine; Amino Acids; Anhydrides; Aspartic Acid; Bacillus; Binding Sites; Detergents; Drug Antagonism; Drug Synergism; Feedback; Glycine; Hot Temperature; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Phosphotransferases; Threonine; Tryptophan; Valine | 1968 |
Incorporation of 2-14C tryptophan into the free amino acid spectrum of Vinca minor L.
Topics: Alanine; Amino Acids; Autoradiography; Carbon Isotopes; Chromatography, Paper; Leucine; Phenylalanine; Plants, Medicinal; Serine; Tryptophan; Valine | 1968 |
A study of 2,4,6-trinitrobenzenesulfonic acid for automated amino acid chromatography.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Autoanalysis; Chromatography; Cystine; Glycine; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Isoleucine; Leucine; Lysine; Methionine; Methods; Nitrobenzenes; Phenylalanine; Proline; Serine; Spectrophotometry; Sulfonic Acids; Temperature; Threonine; Tryptophan; Tyrosine; Urea; Valine | 1968 |
Trace metal requirements for malformin biosynthesis.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Aspergillus; Chromium; Cobalt; Copper; Cysteine; Glutamine; Glycine; Histidine; Iron; Isoleucine; Leucine; Lysine; Manganese; Metals; Molybdenum; Peptide Biosynthesis; Phenylalanine; Plant Growth Regulators; Proline; Serine; Trace Elements; Tryptophan; Tyrosine; Valine; Zinc | 1968 |
Two procedures for accelerated separation of amino acids by column chromatography.
Topics: Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Buffers; Chromatography, Ion Exchange; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Methods; Phenylalanine; Proline; Serine; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
[On the influence of the starting position on migration of substances in paper electrophoresis].
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Asparagine; Cysteine; Electrophoresis; Glucose; Glutamates; Glutamine; Glycine; Histidine; Leucine; Lysine; Methionine; Serine; Serum Albumin; Taurine; Tryptophan | 1968 |
[Diacentration--a simple procedure for ultrafiltration in centrifuges].
Topics: Alanine; Arginine; Blood Glucose; Centrifugation; Chemistry, Clinical; Dialysis; Methods; Proteins; Tissue Extracts; Tryptophan | 1968 |
States of amino acid residues in proteins. XVI. Naphthoquinones with two sulfonic groups as a reagent for discrimation of amino groups in proteins.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chymotrypsin; Colorimetry; Freezing; Glycine; Histidine; Hydrogen-Ion Concentration; Imidazoles; Indicators and Reagents; Insulin; Lysine; Muramidase; Naphthoquinones; Proline; Proteins; Ribonucleases; Serine; Spectrophotometry; Sulfonic Acids; Tryptophan; Tyrosine | 1968 |
Number of polypeptide components in bacteriophage T2L contractile sheaths.
Topics: Alanine; Amino Acids; Aspartic Acid; Carboxypeptidases; Coliphages; Glutamine; Glycine; Hydrazines; Leucine; Peptides; Serine; Threonine; Tryptophan; Valine | 1968 |
In vitro inhibition of brain metabolism during postnatal development by high levels of phenylalanine and tryptophan.
Topics: Acetates; Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Carbon; Carbon Dioxide; Carbon Isotopes; Glucose; Glutamates; In Vitro Techniques; Leucine; Lipid Metabolism; Oxygen Consumption; Phenylalanine; Tryptophan | 1969 |
Action of alpha-methyl-DL-tryptophan in vivo on catabolism of amino acids and their conversion to liver glycogen.
Topics: Acetates; Adrenal Glands; Adrenalectomy; Alanine; Amino Acids; Animals; Body Temperature; Carbon Dioxide; Carbon Isotopes; Glutamates; Histidine; Isoleucine; Leucine; Liver; Liver Glycogen; Male; Pyruvates; Rats; Threonine; Time Factors; Tryptophan; Tryptophan Oxygenase; Urea | 1969 |
Amino acid composition of gluten fractions.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chemical Precipitation; Dialysis; Glutamates; Glutens; Glycine; Hydrogen-Ion Concentration; Lysine; Magnesium Sulfate; Papain; Proline; Salicylates; Sulfates; Sulfites; Threonine; Tryptophan | 1969 |
Circadian periodicity of blood amino acids in normal and adrenalectomized mice.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Circadian Rhythm; Cystine; Densitometry; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Mice; Serine; Threonine; Tryptophan; Tryptophan Oxygenase; Tyrosine; Valine | 1969 |
Urinary amino acid patterns in simple and complicated bilharziasis.
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Ascites; Chromatography, Paper; Cystinuria; Hepatomegaly; Humans; Liver Diseases; Male; Middle Aged; Schistosomiasis; Splenomegaly; Threonine; Tryptophan; Tyrosine | 1969 |
Amino acid composition of beta-caseins from the milks of Bos indicus and Bos taurus cows: a comparative study.
Topics: Acrylates; Alanine; Amino Acids; Animals; Arginine; Autoanalysis; Caseins; Cattle; Cellulose; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Electrophoresis; Gels; Glutamates; Histidine; Lysine; Milk; Peptides; Phosphorus; Serine; Species Specificity; Threonine; Trypsin; Tryptophan | 1969 |
The formation of oxalic acid from the side chain of aromatic amino acids in the rat.
Topics: Alanine; Amino Acid Oxidoreductases; Animals; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Hippurates; Male; Oxalates; Phenylalanine; Rats; Snakes; Tryptophan; Tyrosine; Venoms | 1969 |
Histones in early embryogenesis.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Echinodermata; Electrophoresis; Embryo, Nonmammalian; Fishes; Gels; Genetic Code; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
Ferredoxin from the photosynthetic bacterium, Chlorobium thiosulfatophilum. A link to ferredoxins from nonphotosynthetic bacteria.
Topics: Alanine; Amino Acids; Arginine; Bacteria; Chloroplasts; Clostridium; Ferredoxins; Glycine; Histidine; Iron; Light; Lysine; Methionine; Molecular Weight; Oxidation-Reduction; Plants; Spectrum Analysis; Sulfides; Tryptophan | 1969 |
The utilization of tryptophan by neurospora.
Topics: Alanine; In Vitro Techniques; Indoles; Mutation; Neurospora; ortho-Aminobenzoates; Pyridoxal Phosphate; Pyruvates; Temperature; Tryptophan | 1965 |
The effect of metabolic inhibitors on transport and exchange of amino acids in Ehrlich ascites cells.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Carcinoma, Ehrlich Tumor; Cyanides; Dinitrophenols; Glycine; Hexoses; In Vitro Techniques; Phenylalanine; Tryptophan | 1965 |
Regulation of amino acid accumulation in isolated rat diagphragm: effect of puromycin and insulin.
Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Isotopes; Cystine; Diaphragm; Histidine; In Vitro Techniques; Insulin; Isoleucine; Leucine; Male; Muscles; Phenylalanine; Proteins; Puromycin; Rats; Serine; Tryptophan; Tyrosine | 1965 |
Polyamide layer chromatography of DNP-amino acids.
Topics: Alanine; Amides; Arginine; Aspartic Acid; Chromatography; Dinitrophenols; Glutamates; Glycine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
Further characterization of the subunit of Tamm-Horsfall mucoprotein.
Topics: Alanine; Amino Acids; Chromatography, Gel; Cystine; Electrophoresis; Molecular Weight; Mucoproteins; Peptides; Sulfides; Trypsin; Tryptophan | 1966 |
[Incorporation of C14- and H3-tryptophan into different serum proteins through the perfused isolated normal and irradiated liver].
Topics: Alanine; Albumins; Amino Acids; Animals; Blood Proteins; Carbon Isotopes; Chromatography; Electrophoresis; Globulins; Glycine; Liver; Perfusion; Phenylalanine; Radiation Effects; Rats; Serine; Tritium; Tryptophan | 1966 |
[The influence of certain humoral factors on the rate of food reactions in the fish].
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Citrates; Feeding Behavior; Fishes; Glucose; Histidine; Leucine; Tryptophan; Tyrosine; Valine | 1966 |
[Chromatographic investigation of free amino acids of the heart, kidneys and brain in experimental myocarditis].
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Brain; Chromatography, Paper; Cystine; Glutamine; Glycine; Histidine; Kidney; Lysine; Methionine; Myocarditis; Myocardium; Phenylalanine; Rabbits; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
[Study of amino acid compositiion of basic polypeptides of animal origin by paper chromatography method].
Topics: Alanine; Amino Acids; Animals; Arginine; Brain Chemistry; Cattle; Chromatography, Paper; Cystine; Glutamates; Glycine; Histidine; Humans; Kidney; Liver; Lysine; Peptides; Phenylalanine; Placenta; Serine; Tryptophan; Valine | 1966 |
Inhibition of inorganic phosphate transport by amino acids in rat kidney-cortical slices in vitro.
Topics: Alanine; Amino Acids; Animals; Arginine; Biological Transport; Carbon Isotopes; Dinitrophenols; Glycine; In Vitro Techniques; Kidney; Leucine; Lysine; Male; Phenylalanine; Phosphates; Phosphorus Isotopes; Rats; Temperature; Tryptophan | 1967 |
Calcium and phosphate dependency of amino acid transport in rat kidney-cortical slices in vitro.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Calcium; Carbon Isotopes; In Vitro Techniques; Kidney; Kidney Tubules; Leucine; Male; Parathyroid Glands; Phosphates; Rats; Tryptophan; Vitamin D Deficiency | 1967 |
Rate constants of hydrated electron reactions with peptides and proteins.
Topics: Alanine; Albumins; Asparagine; Electrons; Gelatin; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Molecular Weight; Muramidase; Peptides; Phenylalanine; Proline; Proteins; Ribonucleases; Tryptophan; Tyrosine; Valine | 1967 |
Regulation of glutamine synthetase. II. Patterns of feedback inhibition in microorganisms.
Topics: Adenine Nucleotides; Alanine; Bacteria; Cytosine Nucleotides; Eukaryota; Feedback; Fungi; Glucosamine; Glutamine; Glycine; Histidine; Ligases; Magnesium; Manganese; Tryptophan | 1967 |
Further studies of amino acid transport by embryonic chick bone.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Bone and Bones; Chick Embryo; Dactinomycin; Ethylmaleimide; Glycine; In Vitro Techniques; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
The relation of spectral changes and tritium exchange reactions to the mechanism of tryptophanase-catalyzed reactions.
Topics: Alanine; Catalysis; Chemical Phenomena; Chemistry, Physical; Hydrogen-Ion Concentration; Indoles; Lyases; Magnetic Resonance Spectroscopy; Potassium; Spectrophotometry; Tritium; Tryptophan | 1967 |
Amino acid esters as inhibitors of growth and of aminoacyl transfer ribonucleic acid synthetases in Euglena and Astasia.
Topics: Alanine; Amino Acids; Antimetabolites; Aspartic Acid; Cysteine; Esters; Euglena; Eukaryota; Glutamates; Hydrogen-Ion Concentration; Leucine; Ligases; Methionine; Phenylalanine; RNA, Transfer; Tryptophan; Tyrosine | 1967 |
Inhibitory effect of certain amino acids on renal tubular absorption of phosphate.
Topics: Absorption; Alanine; Animals; Calcium; Dogs; Glycine; Inulin; Kidney Tubules; Male; Phosphates; Phosphorus; Tryptophan; Valine | 1967 |
Synthesis and properties of some N-pyridoxyl-L-amino acids and N-(5-phosphopyridoxyl)-L-amino acids.
Topics: Alanine; Aldehydes; Arginine; Aspartic Acid; Chemistry, Organic; Chromatography, Paper; Glutamates; Organic Chemistry Phenomena; Pyridines; Pyridoxal Phosphate; Pyrrolidinones; Serine; Tryptophan; Tyrosine | 1967 |
Influence of L-tryptophan and its metabolites on gluconeogenesis in the isolated, perfused liver.
Topics: Alanine; Animals; Aspartic Acid; Blood Glucose; Caprylates; Carboxy-Lyases; Fatty Acids; Gluconeogenesis; Lactates; Liver; Malates; Male; Manganese; Oxaloacetates; Perfusion; Pyruvates; Quinolines; Rats; Tryptophan | 1967 |
Chromatographic analysis of free amino acids of gastric juice in patients with cancer and other stomach diseases.
Topics: Adult; Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Cystine; Duodenal Ulcer; Female; Gastric Juice; Glutamates; Histidine; Humans; Leucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Polyps; Stomach Diseases; Stomach Neoplasms; Stomach Ulcer; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Metabolism of beta-cyanoalanine.
Topics: Alanine; Aldehydes; Amino Acids; Animals; Body Weight; Brain Chemistry; Chromatography, Ion Exchange; Crystallization; Cyanides; Dipeptides; Liver; Male; Muscles; Pyridines; Pyridoxine; Rats; Seizures; Tryptophan | 1967 |
Effect of amino acids on zinc-65 incorporation by Ehrlich ascites tumor cells in vitro.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Female; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Lysine; Methionine; Mice; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Zinc; Zinc Isotopes | 1967 |
Effect of combined administration of tryptophan with putative tryptophan pyrrolase inhibitors, DL-3-pyridylalanine, allopurinol or nicotinamide, on brain serotonin concentration.
Topics: Alanine; Allopurinol; Animals; Brain Chemistry; Liver; Male; Niacinamide; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tryptophan Oxygenase | 1984 |
Synthesis of a novel class of heteroaromatic amino acids and their use in the preparation of analogues of luteinizing hormone-releasing hormone.
Topics: Alanine; Animals; Benzothiazoles; Chemical Phenomena; Chemistry; Estrus; Female; Gonadotropin-Releasing Hormone; Methods; Pregnancy; Rats; Tryptophan | 1984 |
[Characterization of the subunits of botulinum neurotoxin type A].
Topics: Alanine; Amino Acids; Botulinum Toxins; Chromatography, Ion Exchange; Clostridium botulinum; Leucine; Peptide Fragments; Protein Conformation; Tryptophan | 1984 |
Interactions of tryptophan synthase, tryptophanase, and pyridoxal phosphate with oxindolyl-L-alanine and 2,3-dihydro-L-tryptophan: support for an indolenine intermediate in tryptophan metabolism.
Topics: Alanine; Binding, Competitive; Chemical Phenomena; Chemistry; Escherichia coli; Kinetics; Lyases; Mass Spectrometry; Oxindoles; Pyridoxal Phosphate; Spectrophotometry; Tryptophan; Tryptophan Synthase; Tryptophanase | 1984 |
Comparative effects of DL, D and L-3-pyridylalanine on serotonin concentration and tryptophan-serotonin metabolizing enzymes.
Topics: Alanine; Animals; Brain; Male; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Tissue Distribution; Tryptophan | 1984 |
Transfer RNA genes associated with the 16S and 23S rRNA genes of Euglena chloroplast DNA.
Topics: Alanine; Chloroplasts; DNA, Circular; Euglena gracilis; Genes; Genetic Linkage; Glutamates; Isoleucine; Nucleic Acid Hybridization; RNA, Ribosomal; RNA, Transfer; Tryptophan | 1980 |
Production of amino acids by analog-resistant mutants of the cyanobacterium Spirulina platensis.
Topics: Alanine; Azetidinecarboxylic Acid; Cyanobacteria; Drug Resistance, Microbial; Ethionine; Methionine; p-Fluorophenylalanine; Phenylalanine; Proline; Tryptophan | 1981 |
Patterns of amino acid efflux from isolated normal and cystinotic human leucocyte lysosomes.
Topics: Alanine; Amino Acids; Cystine; Cystinosis; Esters; Humans; Kinetics; Leucine; Leukocytes; Lysine; Lysosomes; Methionine; Phenylalanine; Tryptophan | 1982 |
Incorporation of amino acid analogs during the biosynthesis of Escherichia coli aspartate transcarbamylase.
Topics: Alanine; Amino Acids; Aspartate Carbamoyltransferase; Escherichia coli; Ethionine; Macromolecular Substances; Methylhistidines; p-Fluorophenylalanine; Phenylalanine; Triazoles; Tryptophan | 1980 |
Noncovalent inhibitors of sickle hemoglobin gelation: effects of aryl-substituted alanines.
Topics: Alanine; Gels; Hemoglobin, Sickle; Humans; Phenylalanine; Solubility; Structure-Activity Relationship; Tryptophan | 1982 |
Effects of benserazide and carbidopa on the metabolism of L-tryptophan by isolated rat liver cells.
Topics: Alanine; Animals; Benserazide; Carbidopa; Chemical Phenomena; Chemistry; Hydrazines; Hydrolases; Liver; Oxidation-Reduction; Pyruvates; Rats; Tryptophan; Tryptophan Oxygenase | 1981 |
The A, ASC, and L systems for the transport of amino acids in Chinese hamster ovary cells (CHO-K1).
Topics: Alanine; Amino Acids; Animals; Biological Transport; Cell Line; Cricetinae; Cricetulus; Female; Kinetics; Ovary; Sodium; Tryptophan | 1981 |
Effect of dl-3-pyridylalanine on serotonin concentration and tryptophan-serotonin metabolizing enzymes in rats.
Topics: Alanine; Animals; Aromatic-L-Amino-Acid Decarboxylases; Male; Monoamine Oxidase; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tryptophan Oxygenase | 1981 |
Tryptophan transport by isolated newborn rabbit jejunum.
Topics: Aging; Alanine; Animals; Animals, Newborn; Intestinal Absorption; Jejunum; Phenylalanine; Rabbits; Sodium; Tryptophan | 1980 |
Role of leucine 201 of thermostable D-amino acid aminotransferase from a thermophile, Bacillus sp. YM-1.
Topics: Alanine; Alanine Transaminase; Bacillus; Bacterial Proteins; Base Sequence; Binding Sites; Catalysis; Circular Dichroism; D-Alanine Transaminase; Enzyme Activation; Enzyme Stability; Hot Temperature; Kinetics; Leucine; Molecular Sequence Data; Mutation; Pyridoxal Phosphate; Pyridoxamine; Spectrometry, Fluorescence; Tryptophan | 1995 |
Mutagenesis of active site residues in type I dehydroquinase from Escherichia coli. Stalled catalysis in a histidine to alanine mutant.
Topics: Alanine; Binding Sites; Escherichia coli; Fluorometry; Histidine; Hydro-Lyases; Isoelectric Focusing; Kinetics; Ligands; Mass Spectrometry; Models, Chemical; Mutagenesis; Recombinant Proteins; Schiff Bases; Shikimic Acid; Tryptophan | 1995 |
Allosteric control of acetylcholinesterase catalysis by fasciculin.
Topics: Acetylcholinesterase; Alanine; Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Animals; Catalysis; Cell Line; Cholinesterase Inhibitors; Elapid Venoms; Humans; Kinetics; Mathematics; Mice; Models, Theoretical; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Transfection; Tryptophan; Tyrosine | 1995 |
Trp-21 is important in the processing and secretion of big endothelin-1.
Topics: Alanine; Cell Line; Chromatography, High Pressure Liquid; DNA, Complementary; Endothelin-1; Endothelins; Gene Expression; Mutagenesis, Site-Directed; Protein Precursors; Structure-Activity Relationship; Transfection; Tryptophan | 1995 |
Evidence by site-directed mutagenesis supports long-range electron transfer in mouse ribonucleotide reductase.
Topics: Alanine; Animals; Aspartic Acid; Base Sequence; Binding Sites; Electron Transport; Free Radicals; Hydrogen Bonding; Macromolecular Substances; Manganese; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Proteins; Ribonucleotide Reductases; Structure-Activity Relationship; Tryptophan; Tyrosine | 1995 |
Studies on the rate of selective uptake of amino acids by Trichinella larvae in vivo.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Glycine; Helminth Proteins; Larva; Male; Mice; Mice, Inbred C57BL; Time Factors; Trichinella; Trichinella spiralis; Trichinellosis; Tritium; Tryptophan; Tyrosine | 1994 |
Accumulation of 3-(phenylamino)alanine, a constituent in L-tryptophan products implicated in eosinophilia-myalgia syndrome, in blood and organs of the Lewis rats.
Topics: Alanine; Animals; Chromatography, High Pressure Liquid; Drug Contamination; Drug Residues; Eosinophilia-Myalgia Syndrome; Female; Rats; Rats, Inbred Lew; Tissue Distribution; Tryptophan | 1995 |
Neutral amino acid transport characterization of isolated luminal and abluminal membranes of the blood-brain barrier.
Topics: Alanine; Amino Acids; Amino Acids, Cyclic; Animals; beta-Alanine; Biological Transport; Blood-Brain Barrier; Cattle; Cell Fractionation; Cell Membrane; Centrifugation, Zonal; Endothelium, Vascular; Ficoll; Glutamine; Kinetics; Leucine; Microcirculation; Phenylalanine; Sodium; Tryptophan | 1995 |
Identification of four metabolites of 3-(phenylamino)alanine, a constituent in L-tryptophan products implicated in eosinophilia-myalgia syndrome, in rats.
Topics: Administration, Oral; Alanine; Animals; Blood-Brain Barrier; Brain; Chromatography, High Pressure Liquid; Drug Contamination; Eosinophilia-Myalgia Syndrome; Gas Chromatography-Mass Spectrometry; Kidney; Liver; Lung; Male; Phenylalanine; Rats; Rats, Wistar; Structure-Activity Relationship; Tissue Distribution; Tryptophan | 1994 |
Probing of the location of the allosteric site on m1 muscarinic receptors by site-directed mutagenesis.
Topics: Acetylcholine; Alanine; Allosteric Regulation; Animals; Base Sequence; Binding Sites; Binding, Competitive; Gallamine Triethiodide; Kinetics; Molecular Sequence Data; Muscarinic Antagonists; Mutagenesis, Site-Directed; Mutation; N-Methylscopolamine; Receptors, Muscarinic; Scopolamine Derivatives; Tritium; Tryptophan | 1995 |
Tryptophanase from Escherichia coli: catalytic and spectral properties in water-organic solvents.
Topics: Alanine; Catalysis; Cysteine; Dimethylformamide; Escherichia coli; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Methanol; Pyridoxal Phosphate; Solutions; Spectrophotometry, Ultraviolet; Stereoisomerism; Substrate Specificity; Tryptophan; Tryptophanase; Water | 1994 |
Critical side-chain interactions at a subunit interface in the Arc repressor dimer.
Topics: Alanine; Bacteriophage P22; Biophysical Phenomena; Biophysics; Circular Dichroism; Escherichia coli; Isoleucine; Models, Molecular; Molecular Structure; Mutagenesis, Insertional; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Repressor Proteins; Spectrometry, Fluorescence; Thermodynamics; Tryptophan; Valine; Viral Proteins; Viral Regulatory and Accessory Proteins | 1995 |
Affinity of native kappa-bungarotoxin and site-directed mutants for the muscle nicotinic acetylcholine receptor.
Topics: Alanine; Amino Acid Sequence; Animals; Bungarotoxins; Cell Division; Cell Line; Chick Embryo; Dose-Response Relationship, Drug; Fibroblasts; Glutamine; Lysine; Mice; Molecular Sequence Data; Muscle, Skeletal; Mutagenesis, Site-Directed; Proline; Quail; Receptors, Nicotinic; Recombinant Proteins; Sequence Homology, Amino Acid; Snake Venoms; Tryptophan | 1994 |
NMR studies of 1H resonances in the 10-18-ppm range for aspartate aminotransferase from Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Asparagine; Aspartate Aminotransferases; Escherichia coli; Histidine; Hydrogen; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins; Sensitivity and Specificity; Tryptophan | 1994 |
The role of tryptophan 97 of cytochrome P450 BM3 from Bacillus megaterium in catalytic function. Evidence against the 'covalent switching' hypothesis of P-450 electron transfer.
Topics: Alanine; Bacillus megaterium; Bacterial Proteins; Base Sequence; Catalysis; Circular Dichroism; Cytochrome P-450 Enzyme System; DNA Primers; Electron Spin Resonance Spectroscopy; Electron Transport; Escherichia coli; Heme; Mixed Function Oxygenases; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADPH-Ferrihemoprotein Reductase; Phenylalanine; Protein Structure, Secondary; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1994 |
Active site coordination chemistry of the cytochrome c peroxidase Asp235Ala variant: spectroscopic and functional characterization.
Topics: Alanine; Aspartic Acid; Base Sequence; Binding Sites; Cytochrome-c Peroxidase; Electron Spin Resonance Spectroscopy; Heme; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Iron; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Recombinant Proteins; Spectrum Analysis; Structure-Activity Relationship; Temperature; Tryptophan | 1994 |
Modulation of the kynurenine pathway in search for new neuroprotective agents. Synthesis and preliminary evaluation of (m-nitrobenzoyl)alanine, a potent inhibitor of kynurenine-3-hydroxylase.
Topics: Alanine; Animals; Anticonvulsants; Binding, Competitive; Brain; Hippocampus; Hydrolases; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Liver; Mixed Function Oxygenases; Models, Molecular; Molecular Structure; Motor Activity; Rats; Seizures; Tryptophan | 1994 |
Effect of 3-phenylamino-L-alanine on tryptophan binding to rat hepatic nuclear envelopes.
Topics: Alanine; Animals; Cell Nucleus; Drug Contamination; Female; Kinetics; Liver; Macrophages; Mice; Microsomes, Liver; Nuclear Envelope; Rats; Rats, Sprague-Dawley; Tritium; Tryptophan | 1994 |
In vivo increase of passive intestinal absorption by cotransporter activation in rat.
Topics: Alanine; Animals; Biological Transport, Active; Cytoskeleton; Deoxyglucose; Diffusion; Galactose; Intercellular Junctions; Intestinal Absorption; Jejunum; Male; Mannitol; Rats; Rats, Wistar; Sodium; Sorbitol; Tryptophan | 1993 |
Estimation of the number of enantioselective sites of bovine serum albumin using frontal chromatography.
Topics: Adsorption; Alanine; Binding Sites; Chromatography, Affinity; Mandelic Acids; Phenylbutyrates; Serum Albumin, Bovine; Stereoisomerism; Structure-Activity Relationship; Tryptophan | 1993 |
Active sites of the cytochrome p450cam (CYP101) F87W and F87A mutants. Evidence for significant structural reorganization without alteration of catalytic regiospecificity.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Camphor 5-Monooxygenase; Cloning, Molecular; Cytochrome P-450 Enzyme System; Escherichia coli; Ferricyanides; Hydrazines; Mixed Function Oxygenases; Models, Molecular; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Protein Conformation; Protoporphyrins; Recombinant Proteins; Spectrophotometry; Tryptophan | 1993 |
The role of conserved tryptophan residues in the interaction of a bacterial cellulose binding domain with its ligand.
Topics: Alanine; Alkaline Phosphatase; Amino Acid Sequence; Blotting, Western; Cellulose; Electrophoresis, Polyacrylamide Gel; Endo-1,4-beta Xylanases; Escherichia coli; Glycoside Hydrolases; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Pseudomonas fluorescens; Recombinant Fusion Proteins; Tryptophan | 1993 |
Tryptophan super-repressors with alanine 77 changes.
Topics: Alanine; Amino Acid Sequence; Apoproteins; Bacterial Proteins; Base Sequence; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Repressor Proteins; Tryptophan | 1993 |
Aromatic side-chain contribution to far-ultraviolet circular dichroism of helical peptides and its effect on measurement of helix propensities.
Topics: Alanine; Amino Acid Sequence; Circular Dichroism; Molecular Sequence Data; Peptides; Protein Conformation; Protein Structure, Secondary; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tryptophan; Tyrosine | 1993 |
Subchronic toxicity of 3-phenylamino alanine, an impurity in L-tryptophan reported to be associated with eosinophilia-myalgia syndrome.
Topics: Administration, Oral; Alanine; Animals; Blood Chemical Analysis; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Eosinophilia-Myalgia Syndrome; Female; Heart; Kidney; Liver; Macrophages, Alveolar; Male; Organ Size; Random Allocation; Rats; Rats, Sprague-Dawley; Testis; Tissue Distribution; Tryptophan | 1995 |
The effect of different amino acid side chains on the stereospecificity and catalytic efficiency of the tryptophan synthase-catalysed exchange of the alpha-protons of amino acids.
Topics: Alanine; Binding Sites; Catalysis; Cloning, Molecular; Escherichia coli; Glycine; Kinetics; Macromolecular Substances; Magnetic Resonance Spectroscopy; Mathematics; Models, Theoretical; Recombinant Proteins; Salmonella typhimurium; Substrate Specificity; Tryptophan; Tryptophan Synthase | 1996 |
Three distinct structural environments of a transmembrane domain in the inwardly rectifying potassium channel ROMK1 defined by perturbation.
Topics: Alanine; Amino Acid Sequence; Animals; Cell Membrane; Female; Membrane Potentials; Models, Molecular; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Point Mutation; Polymerase Chain Reaction; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Structure, Secondary; Recombinant Proteins; Tryptophan; Xenopus | 1995 |
Identification of a critical ligand binding determinant of the human erythropoietin receptor. Evidence for common ligand binding motifs in the cytokine receptor family.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Cell Line; Cell Membrane; Chlorocebus aethiops; Cloning, Molecular; Conserved Sequence; Erythropoietin; Escherichia coli; Humans; Kinetics; Ligands; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Protein Structure, Secondary; Receptors, Cytokine; Receptors, Erythropoietin; Recombinant Proteins; Sequence Homology, Amino Acid; Transfection; Tryptophan; Tyrosine | 1996 |
Lipoprotein lipase binds to low density lipoprotein receptors and induces receptor-mediated catabolism of very low density lipoproteins in vitro.
Topics: Alanine; Binding Sites; Catalysis; Cells, Cultured; Emulsions; Fat Emulsions, Intravenous; Fibroblasts; Glutathione Transferase; Humans; Kinetics; Lipoprotein Lipase; Lipoproteins, VLDL; Male; Mutagenesis, Site-Directed; Point Mutation; Receptors, LDL; Recombinant Fusion Proteins; Skin; Tryptophan | 1996 |
Point mutations characterize KEL10, the KEL3, KEL4, and KEL21 alleles, and the KEL17 and KEL11 alleles.
Topics: Alanine; Alleles; Amino Acid Sequence; Arginine; Base Sequence; Codon; DNA; Exons; Glutamic Acid; Glutamine; Humans; Kell Blood-Group System; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Sequence Analysis, DNA; Tryptophan; Valine | 1996 |
Identification of putative active-site residues in the DNase domain of colicin E9 by random mutagenesis.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Colicins; Conserved Sequence; Deoxyribonucleases; DNA; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Sequence Alignment; Spectrometry, Fluorescence; Tryptophan | 1996 |
Transcription factor recognition surface on the RNA polymerase alpha subunit is involved in contact with the DNA enhancer element.
Topics: Alanine; Amino Acid Sequence; Arginine; Bacterial Proteins; Binding Sites; Cyclic AMP Receptor Protein; DNA Footprinting; DNA-Directed RNA Polymerases; DNA, Bacterial; Enhancer Elements, Genetic; Escherichia coli; Gene Expression Regulation, Bacterial; Lac Operon; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Plants; Protein Binding; Protein Structure, Secondary; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Species Specificity; Transcription, Genetic; Tryptophan | 1996 |
Comparative histopathologic evaluation of animal studies: murine studies with L-tryptophan and constitutents.
Topics: Alanine; Animals; Drug Combinations; Mice; Mice, Inbred Strains; Muscle, Skeletal; Muscular Diseases; Skin; Skin Diseases; Tryptophan | 1996 |
A comparative study of tissue distribution and excretion among three substances implicated in eosinophilia-myalgia syndrome.
Topics: Alanine; Animals; Biotransformation; Brain; Carbolines; Eosinophilia-Myalgia Syndrome; Humans; Kidney; Liver; Rats; Tissue Distribution; Tryptophan | 1996 |
Synthesis and analysis of contaminants in ems-related tryptophan.
Topics: Alanine; Chromatography, High Pressure Liquid; Drug Contamination; Eosinophilia-Myalgia Syndrome; Humans; Tryptophan; Tryptophanase | 1996 |
Molecular design and characterization of an alpha-thrombin inhibitor containing a novel P1 moiety.
Topics: Alanine; Animals; Binding Sites; Crystallography, X-Ray; Drug Design; Hirudins; Models, Molecular; Oligopeptides; Partial Thromboplastin Time; Peptide Fragments; Protein Conformation; Rats; Serine Proteinase Inhibitors; Software; Thrombin; Trypsin; Trypsin Inhibitors; Tryptophan | 1997 |
Mouse strain and source of L-tryptophan affects hepatic nuclear tryptophan binding.
Topics: Alanine; Animals; Binding, Competitive; Cell Nucleus; Liver; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Inbred NZB; Protein Biosynthesis; Selenic Acid; Selenium Compounds; Sodium Selenite; Tryptophan | 1997 |
Scanning mutagenesis of the putative transmembrane segments of Kir2.1, an inward rectifier potassium channel.
Topics: Alanine; Amino Acid Sequence; Animals; Macromolecular Substances; Membrane Potentials; Models, Structural; Molecular Sequence Data; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Point Mutation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Structure, Secondary; Recombinant Proteins; Transcription, Genetic; Tryptophan; Xenopus laevis | 1997 |
Structure and dynamics of hydronium in the ion channel gramicidin A.
Topics: Alanine; Dimerization; Gramicidin; Hydrogen Bonding; Ion Channels; Kinetics; Models, Molecular; Onium Compounds; Protein Conformation; Tryptophan; Valine | 1996 |
Alanine-scanning mutagenesis of Bacillus subtilis trp RNA-binding attenuation protein (TRAP) reveals residues involved in tryptophan binding and RNA binding.
Topics: Alanine; Asparagine; Bacillus subtilis; Bacterial Proteins; Binding Sites; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; RNA; RNA-Binding Proteins; Transcription Factors; Tryptophan | 1997 |
Chiral recognition by the copper(II) complex of 6-deoxy-6-N-(2-methylaminopyridine)-beta-cyclodextrin.
Topics: Alanine; Aminopyridines; beta-Cyclodextrins; Calorimetry; Chromatography, High Pressure Liquid; Circular Dichroism; Copper; Cyclodextrins; Electron Spin Resonance Spectroscopy; Magnetic Resonance Spectroscopy; Molecular Conformation; Potentiometry; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stereoisomerism; Thermodynamics; Tryptophan | 1997 |
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.
Topics: Alanine; Amino Acid Sequence; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Binding Sites; Cell Line; Electrophysiology; Enflurane; Ethanol; Glycine; Humans; Molecular Sequence Data; Mutagenesis; Propofol; Receptors, GABA-A; Receptors, Glycine; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Tryptophan; Xenopus | 1997 |
Alanine insertion scanning mutagenesis of lactose permease transmembrane helices.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cell Membrane; Escherichia coli; Escherichia coli Proteins; Lactose; Membrane Transport Proteins; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Insertional; Protein Structure, Secondary; Symporters; Tryptophan | 1997 |
Effects of alanine and glycine substitution for tryptophan on the heterogeneity of gramicidin A analogs in micelles.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Circular Dichroism; Glycine; Gramicidin; Micelles; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary; Sodium Dodecyl Sulfate; Structure-Activity Relationship; Tryptophan | 1997 |
Effect of replacement of His-118, His-125 and Trp-143 by alanine on the catalytic activity and subunit assembly of inorganic pyrophosphatase from thermophilic bacterium PS-3.
Topics: Alanine; Amino Acid Substitution; Enzyme Activation; Escherichia coli; Histidine; Inorganic Pyrophosphatase; Protein Conformation; Pyrophosphatases; Structure-Activity Relationship; Tryptophan | 1998 |
Specificity of alcohol dehydrogenases for sulfoxides.
Topics: Alanine; Alcohol Dehydrogenase; Amino Acid Substitution; Animals; Binding Sites; Enzyme Inhibitors; Horses; Humans; Isoenzymes; Models, Molecular; Mutation; Phenylalanine; Structure-Activity Relationship; Substrate Specificity; Sulfoxides; Tryptophan | 1998 |
Differences in the catalytic efficiencies of allelic variants of glutathione transferase P1-1 towards carcinogenic diol epoxides of polycyclic aromatic hydrocarbons.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Alanine; Alleles; Carcinogens; Catalysis; Glutathione Transferase; Mutation; Stereoisomerism; Tryptophan | 1998 |
Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes.
Topics: Alanine; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Binding Sites; Coenzymes; Crystallography, X-Ray; Horses; Ligands; Liver; Models, Molecular; NAD; Niacinamide; Phenylalanine; Structure-Activity Relationship; Substrate Specificity; Tryptophan; Valine | 1998 |
Differential scanning calorimetry study of the thermodynamic stability of some mutants of Sso7d from Sulfolobus solfataricus.
Topics: Alanine; Amino Acid Substitution; Archaeal Proteins; Calorimetry, Differential Scanning; DNA-Binding Proteins; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Osmolar Concentration; Phenylalanine; Protein Denaturation; Sulfolobus; Thermodynamics; Tryptophan; Tyrosine | 1998 |
A novel mutation in the switch 3 region of Gsalpha in a patient with Albright hereditary osteodystrophy impairs GDP binding and receptor activation.
Topics: Adenylyl Cyclases; Adult; Alanine; Aluminum Compounds; Amino Acid Sequence; Arginine; Base Sequence; Binding Sites; Cloning, Molecular; Erythrocyte Membrane; Escherichia coli; Exons; Female; Fibrous Dysplasia, Polyostotic; Fluorides; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Male; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Protein Biosynthesis; Protein Structure, Secondary; Receptors, Cell Surface; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Tryptophan | 1998 |
Mutations of Gly to Ala in human glutathione transferase P1-1 affect helix 2 (G-site) and induce positive cooperativity in the binding of glutathione.
Topics: Alanine; Binding Sites; Circular Dichroism; Cysteine; Escherichia coli; Glutathione; Glutathione S-Transferase pi; Glutathione Transferase; Glycine; Humans; Isoenzymes; Kinetics; Models, Molecular; Mutation; Protein Conformation; Recombinant Proteins; Spectrophotometry, Ultraviolet; Tryptophan | 1998 |
Ruminal escape and apparent degradation of amino acids administered intraruminally in mixtures to cows.
Topics: Alanine; Amino Acids; Amino Acids, Essential; Animals; Arginine; Cattle; Female; Mathematics; Rumen; Tryptophan | 1998 |
Histidine77, glutamic acid81, glutamic acid123, threonine126, asparagine194, and tryptophan197 of the human emopamil binding protein are required for in vivo sterol delta 8-delta 7 isomerization.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Asparagine; Carrier Proteins; Cell Membrane; Glutamic Acid; Histidine; Humans; Isoenzymes; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Peptide Fragments; Piperidines; Saccharomyces cerevisiae; Steroid Isomerases; Threonine; Tryptophan | 1999 |
The differential specificity of chymotrypsin A and B is determined by amino acid 226.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Catalytic Domain; Cattle; Chymotrypsin; Glycine; Models, Molecular; Molecular Sequence Data; Mutagenesis; Phenylalanine; Protein Isoforms; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Serine Endopeptidases; Substrate Specificity; Tryptophan; Tyrosine | 1999 |
Monitoring the sizes of denatured ensembles of staphylococcal nuclease proteins: implications regarding m values, intermediates, and thermodynamics.
Topics: Alanine; Amino Acid Substitution; Chromatography, Gel; Chromatography, High Pressure Liquid; Chymotrypsinogen; Micrococcal Nuclease; Mutagenesis, Site-Directed; Protein Denaturation; Reproducibility of Results; Spectrometry, Fluorescence; Thermodynamics; Threonine; Tryptophan; Urea; Valine | 1998 |
An electron spin-echo envelope modulation (ESEEM) study of the QA binding pocket of PS II reaction centers from spinach and Synechocystis.
Topics: Alanine; Binding Sites; Cyanobacteria; Electron Spin Resonance Spectroscopy; Histidine; Intracellular Membranes; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Plastoquinone; Spinacia oleracea; Tryptophan | 1999 |
Enzymatic syntheses of 6-(4H-selenolo[3,2-b]pyrrolyl)-L-alanine, 4-(6H-selenolo[2,3-b]pyrrolyl)-L-alanine, and 6-(4H-furo[3,2-b]pyrrolyl-L-alanine.
Topics: Alanine; Cell Division; Escherichia coli; Furans; Organoselenium Compounds; Salmonella typhimurium; Tryptophan; Tryptophan Synthase | 1999 |
Mutagenesis of two conserved tryptophan residues of the E-type ATPases: inactivation and conversion of an ecto-apyrase to an ecto-NTPase.
Topics: Acid Anhydride Hydrolases; Adenine Nucleotides; Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Brain; Chymotrypsin; Conserved Sequence; COS Cells; Enzyme Inhibitors; Escherichia coli; Glutamic Acid; Humans; Hydrolysis; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleoside-Triphosphatase; Protein Folding; Sodium Azide; Transfection; Triazines; Tryptophan | 1999 |
Residues in the alphaH and alphaI helices of the HIV-1 reverse transcriptase thumb subdomain required for the specificity of RNase H-catalyzed removal of the polypurine tract primer.
Topics: Alanine; Base Sequence; DNA; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Protein Structure, Secondary; Ribonuclease H; RNA; Substrate Specificity; Tryptophan | 1999 |
Chromophore-protein-water interactions in the L intermediate of bacteriorhodopsin: FTIR study of the photoreaction of L at 80 K.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Bacteriorhodopsins; Cold Temperature; Halobacterium salinarum; Hydrogen; Models, Molecular; Oxygen; Photochemistry; Schiff Bases; Spectroscopy, Fourier Transform Infrared; Threonine; Tryptophan; Valine; Water | 1999 |
Effects of release factor 1 on in vitro protein translation and the elaboration of proteins containing unnatural amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacterial Proteins; Dimerization; Escherichia coli; Escherichia coli Proteins; HIV Protease; Hot Temperature; Peptide Termination Factors; Plasmids; Protein Biosynthesis; Species Specificity; Tetrahydrofolate Dehydrogenase; Transcription, Genetic; Tryptophan | 1999 |
Effects of substitution of tryptophan 412 in the substrate activation pathway of yeast pyruvate decarboxylase.
Topics: Alanine; Amino Acid Substitution; Apoenzymes; Binding Sites; Circular Dichroism; Enzyme Activation; Enzyme Stability; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Protein Structure, Tertiary; Pyruvate Decarboxylase; Recombinant Proteins; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Substrate Specificity; Thiamine Pyrophosphate; Tryptophan | 1999 |
The free energies for mutating S27 and W79 to alanine in streptavidin and its biotin complex: the relative size of polar and nonpolar free energies on biotin binding.
Topics: Alanine; Amino Acid Substitution; Biotin; Computer Simulation; Mutation; Protein Binding; Serine; Static Electricity; Streptavidin; Thermodynamics; Tryptophan | 1999 |
Tryptophan mediated photoreduction of disulfide bond causes unusual fluorescence behaviour of Fusarium solani pisi cutinase.
Topics: Alanine; Amides; Carboxylic Ester Hydrolases; Cysteine; Disulfides; Fluorescence; Fusarium; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Sulfhydryl Compounds; Sulfhydryl Reagents; Tryptophan | 1999 |
Activation of recombinant bovine matrix metalloproteinase-20 and its hydrolysis of two amelogenin oligopeptides.
Topics: Alanine; Ameloblasts; Amelogenin; Amino Acids; Animals; Calcium; Cattle; Chromatography, Affinity; Chromatography, Ion Exchange; Dental Enamel Proteins; Dialysis; Enzyme Activation; Escherichia coli; Gene Expression Regulation, Enzymologic; Genetic Vectors; Hydrolysis; Leucine; Mass Spectrometry; Matrix Metalloproteinase 20; Matrix Metalloproteinases; Proline; Recombinant Proteins; Tryptophan; Zinc | 1999 |
Roles of active site aromatic residues in catalysis by ketosteroid isomerase from Pseudomonas putida biotype B.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Catalysis; Equilenin; Kinetics; Mutagenesis, Site-Directed; Nandrolone; Phenylalanine; Pseudomonas putida; Recombinant Proteins; Spectrometry, Fluorescence; Steroid Isomerases; Tryptophan; Tyrosine | 1999 |
Tryptophan H33 plays an important role in pyrimidine (6-4) pyrimidone photoproduct binding by a high-affinity antibody.
Topics: Alanine; Amino Acid Substitution; Antibody Affinity; Antibody Specificity; Chromatography, Affinity; DNA; Immunoglobulin Fragments; Immunoglobulin Variable Region; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Protein Folding; Pyrimidine Dimers; Spectrometry, Fluorescence; Surface Plasmon Resonance; Tryptophan; Tyrosine | 1999 |
A hydrophobic patch in ecotropic murine leukemia virus envelope protein is the putative binding site for a critical tyrosine residue on the cellular receptor.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Animals; Binding Sites; Cell Line, Transformed; Friend murine leukemia virus; Glycoproteins; Humans; Membrane Glycoproteins; Methionine; Mice; Models, Molecular; Molecular Sequence Data; Moloney murine leukemia virus; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Protein Processing, Post-Translational; Receptors, Virus; Retroviridae Proteins, Oncogenic; Sequence Homology, Amino Acid; Tryptophan; Tyrosine; Viral Envelope Proteins | 1999 |
The glycine residue in cyclic lactam analogues of galanin(1-16)-NH2 is important for stabilizing an N-terminal helix.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cell Line; Circular Dichroism; Energy Transfer; Galanin; Glycine; Humans; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Peptides, Cyclic; Protein Structure, Secondary; Spectrometry, Fluorescence; Tryptophan; Tumor Cells, Cultured; Tyrosine | 1999 |
Requirement of calmodulin binding by HIV-1 gp160 for enhanced FAS-mediated apoptosis.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Apoptosis; Binding Sites; Calmodulin; Caspase 3; Caspases; Enzyme Activation; fas Receptor; HIV Envelope Protein gp160; HIV-1; Humans; Jurkat Cells; Models, Molecular; Molecular Sequence Data; Myosin-Light-Chain Kinase; Peptide Fragments; Point Mutation; Protein Structure, Secondary; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Sphingosine; Transfection; Tryptophan | 2000 |
Functional inactivation of the nociceptin receptor by alanine substitution of glutamine 286 at the C terminus of transmembrane segment VI: evidence from a site-directed mutagenesis study of the ORL1 receptor transmembrane-binding domain.
Topics: Alanine; Amino Acid Substitution; Animals; Asparagine; CHO Cells; Cricetinae; Glutamine; Humans; Membrane Proteins; Mutagenesis, Site-Directed; Nociceptin Receptor; Phenylalanine; Protein Conformation; Receptors, Opioid; Signal Transduction; Tryptophan; Tyrosine | 2000 |
Vertical-scanning mutagenesis of a critical tryptophan in the "minor groove binding track" of HIV-1 reverse transcriptase. Major groove DNA adducts identify specific protein interactions in the minor groove.
Topics: Adenine; Alanine; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Binding Sites; Consensus Sequence; Epoxy Compounds; Glycine; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Stereoisomerism; Templates, Genetic; Tryptophan | 2000 |
Synthesis of beta-(1-azulenyl)-L-alanine as a potential blue-colored fluorescent tryptophan analog and its use in peptide synthesis.
Topics: Alanine; Azulenes; Circular Dichroism; Fluorescent Dyes; Gastrins; Models, Chemical; Peptide Biosynthesis; Sesquiterpenes; Spectrophotometry; Tryptophan | 2000 |
Alanine mutagenesis of high-mobility-group-protein-1 box B (HMG1-B).
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Carrier Proteins; Circular Dichroism; DNA; DNA-Binding Proteins; Fluorescence; Guanidine; High Mobility Group Proteins; HMGB1 Protein; Models, Molecular; Molecular Sequence Data; Mutation; Phenylalanine; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Temperature; Thermodynamics; Tryptophan | 2000 |
Two novel mutations in the WASP gene in Wiskott-Aldrich patients of Chile origin: W64R and A124E.
Topics: Alanine; Amino Acid Substitution; Arginine; Chile; Glutamic Acid; Humans; Infant; Male; Point Mutation; Proteins; Tryptophan; Wiskott-Aldrich Syndrome; Wiskott-Aldrich Syndrome Protein | 2000 |
A single amino acid substitution (Trp(666)-->Ala) in the interbox1/2 region of the interleukin-6 signal transducer gp130 abrogates binding of JAK1, and dominantly impairs signal transduction.
Topics: Alanine; Animals; Antigens, CD; B-Lymphocytes; Cell Division; COS Cells; Cytokine Receptor gp130; Cytoplasm; Dose-Response Relationship, Drug; Interleukin-6; Janus Kinase 1; Membrane Glycoproteins; Mice; Mutagenesis, Site-Directed; Point Mutation; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptors, Interleukin; Receptors, Interleukin-5; Signal Transduction; Transcriptional Activation; Transfection; Tryptophan | 2000 |
The annexin A3-membrane interaction is modulated by an N-terminal tryptophan.
Topics: Alanine; Annexin A3; Calcium; Electrophysiology; Humans; Liposomes; Membranes; Models, Molecular; Permeability; Phospholipids; Protein Conformation; Protein Denaturation; Protein Folding; Tryptophan; Urea | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Redox properties of protein disulfide bond in oxidized thioredoxin and lysozyme: a pulse radiolysis study.
Topics: Alanine; Amino Acid Substitution; Animals; Anions; Aspartic Acid; Chickens; Chlamydomonas reinhardtii; Disulfides; Electrons; Free Radicals; Muramidase; Mutagenesis, Site-Directed; Oxidation-Reduction; Protons; Pulse Radiolysis; Sulfhydryl Compounds; Thioredoxins; Tryptophan | 2000 |
Biological function and site II Ca2+-induced opening of the regulatory domain of skeletal troponin C are impaired by invariant site I or II Glu mutations.
Topics: Alanine; Animals; Calcium; Chickens; Circular Dichroism; Escherichia coli; Glutamic Acid; Muscle Fibers, Skeletal; Muscle, Skeletal; Mutagenesis, Site-Directed; Myocardium; Plasmids; Protein Binding; Protein Structure, Tertiary; Rabbits; Recombinant Proteins; Spectrometry, Fluorescence; Troponin C; Tryptophan; Ultraviolet Rays | 2000 |
Characterization of the binding site on the formyl peptide receptor using three receptor mutants and analogs of Met-Leu-Phe and Met-Met-Trp-Leu-Leu.
Topics: Alanine; Animals; Anti-HIV Agents; Arginine; Asparagine; Aspartic Acid; Binding Sites; Chemotaxis; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Enfuvirtide; Guanosine 5'-O-(3-Thiotriphosphate); HIV Envelope Protein gp41; Humans; Kinetics; Leucine; Ligands; Methionine; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Peptide Biosynthesis; Peptide Fragments; Phenylalanine; Protein Binding; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Sodium; Tryptophan | 2000 |
Diphtheria toxin NAD affinity and ADP ribosyltransferase activity are reduced at tryptophan 153 substitutions for alanine or phenylalanine.
Topics: Adenosine Diphosphate Ribose; Alanine; Amino Acid Substitution; Diphtheria Toxin; Mutagenesis, Site-Directed; NAD; Peptide Fragments; Phenylalanine; Poly(ADP-ribose) Polymerases; Temperature; Tryptophan | 2000 |
Dopamine transporter tryptophan mutants highlight candidate dopamine- and cocaine-selective domains.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding, Competitive; Carrier Proteins; Cations; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Immunohistochemistry; Ions; Membrane Glycoproteins; Membrane Transport Proteins; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Protein Conformation; Radioligand Assay; Signal Transduction; Tritium; Tryptophan | 2000 |
Antibacterial activity of 15-residue lactoferricin derivatives.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Anti-Bacterial Agents; Circular Dichroism; Escherichia coli; Humans; Lactoferrin; Molecular Sequence Data; Peptide Fragments; Protein Structure, Secondary; Sequence Alignment; Staphylococcus aureus; Tryptophan | 2000 |
Ubiquinone binding, ubiquinone exclusion, and detailed cofactor conformation in a mutant bacterial reaction center.
Topics: Alanine; Binding Sites; Carotenoids; Crystallography, X-Ray; Models, Molecular; Molecular Conformation; Mutation; Photosynthetic Reaction Center Complex Proteins; Rhodobacter sphaeroides; Tryptophan; Ubiquinone | 2000 |
Trp-676 facilitates nicotinamide coenzyme exchange in the reductive half-reaction of human cytochrome P450 reductase: properties of the soluble W676H and W676A mutant reductases.
Topics: Alanine; Binding Sites; Catalysis; Cytochrome c Group; Enzyme Activation; Flavin-Adenine Dinucleotide; Histidine; Humans; Kinetics; Mutagenesis, Site-Directed; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Protein Structure, Tertiary; Recombinant Proteins; Solubility; Spectrometry, Fluorescence; Thermodynamics; Tryptophan | 2000 |
Role of two histidines in the (6-4) photolyase reaction.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Deoxyribodipyrimidine Photo-Lyase; Deuterium Oxide; DNA Repair; Glutamine; Histidine; Hydrogen-Ion Concentration; Leucine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protons; Sequence Homology, Amino Acid; Substrate Specificity; Time Factors; Tryptophan; Xenopus | 2001 |
Structure-activity relationships of trout bradykinin ([Arg(0),Trp(5),Leu(8)]-bradykinin).
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Bradykinin; Bradykinin Receptor Antagonists; Circular Dichroism; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Leucine; Muscle Contraction; Muscle, Smooth; Peptide Biosynthesis; Protein Conformation; Quinolines; Sodium Dodecyl Sulfate; Stereoisomerism; Structure-Activity Relationship; Trifluoroethanol; Trout; Tryptophan | 2000 |
Trp 346 and Leu 352 residues in protective antigen are required for the expression of anthrax lethal toxin activity.
Topics: Alanine; Animals; Antigens, Bacterial; Bacterial Toxins; Blotting, Western; Cell Line; Cell Membrane; Cytosol; Electrophoresis, Polyacrylamide Gel; Endocytosis; Escherichia coli; Hydrogen-Ion Concentration; Leucine; Methionine; Mice; Mutagenesis; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Transport; Trypsin; Tryptophan | 2001 |
Interactions between mastoparan B and the membrane studied by 1H NMR spectroscopy.
Topics: Alanine; Cell Membrane; Circular Dichroism; Dimyristoylphosphatidylcholine; Intercellular Signaling Peptides and Proteins; Lipid Bilayers; Magnetic Resonance Spectroscopy; Micelles; Models, Molecular; Peptides; Phospholipid Ethers; Phosphorylcholine; Protein Conformation; Protein Structure, Secondary; Structure-Activity Relationship; Tryptophan; Wasp Venoms | 2001 |
Structural similarities between glutamate receptor channels and K(+) channels examined by scanning mutagenesis.
Topics: Alanine; Animals; Bacterial Proteins; Cell Line; Crystallization; GluK2 Kainate Receptor; Humans; Ion Channel Gating; Kidney; Membrane Potentials; Models, Chemical; Molecular Sequence Data; Mutagenesis; Oocytes; Patch-Clamp Techniques; Polyamines; Potassium Channels; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Glutamate; Receptors, Kainic Acid; Sequence Homology, Amino Acid; Tryptophan; Xenopus laevis | 2001 |
Sensitivity of single membrane-spanning alpha-helical peptides to hydrophobic mismatch with a lipid bilayer: effects on backbone structure, orientation, and extent of membrane incorporation.
Topics: Alanine; Amides; Amino Acid Sequence; Leucine; Lipid Bilayers; Lysine; Membrane Proteins; Models, Chemical; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Tryptophan | 2001 |
How Ala-->Gly mutations in different helices affect the stability of the apomyoglobin molten globule.
Topics: Alanine; Amino Acid Substitution; Animals; Anions; Apoproteins; Chlorides; Circular Dichroism; Glycine; Hot Temperature; Mutagenesis, Site-Directed; Myoglobin; Perchlorates; Protein Folding; Protein Structure, Secondary; Spectrometry, Fluorescence; Sulfates; Thermodynamics; Trichloroacetic Acid; Tryptophan; Whales | 2001 |
Incorporation of beta-selenolo[3,2-b]pyrrolyl-alanine into proteins for phase determination in protein X-ray crystallography.
Topics: Alanine; Annexin A5; Bacterial Proteins; Crystallography, X-Ray; Escherichia coli; Models, Molecular; Mutation; Organoselenium Compounds; Protein Conformation; Proteins; Recombinant Proteins; Spectrum Analysis; Thermodynamics; Tryptophan | 2001 |
An essential residue in the flexible peptide linking the two idiosynchratic domains of bacterial tyrosyl-tRNA synthetases.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Enzyme Activation; Geobacillus stearothermophilus; Kinetics; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phenylalanine; Protein Structure, Tertiary; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship; Thermodynamics; Tryptophan; Tyrosine; Tyrosine-tRNA Ligase | 2001 |
Proteins with beta-(thienopyrrolyl)alanines as alternative chromophores and pharmaceutically active amino acids.
Topics: Alanine; Annexin A5; Bacterial Proteins; Bridged Bicyclo Compounds, Heterocyclic; Circular Dichroism; Escherichia coli; Fermentation; Hot Temperature; Humans; Models, Molecular; Molecular Mimicry; Protein Biosynthesis; Protein Conformation; Protein Engineering; Proteins; Tryptophan | 2001 |
Optimized aminolysis conditions for cleavage of N-protected hydrophobic peptides from solid-phase resins.
Topics: Alanine; Chromatography, High Pressure Liquid; Fluorenes; Gramicidin; Leucine; Peptides; Resins, Plant; Tryptophan | 2001 |
Identification of potential substrate-binding sites in yeast and human acyl-CoA sterol acyltransferases by mutagenesis of conserved sequences.
Topics: Acyltransferases; Alanine; Amino Acid Sequence; Animals; Binding Sites; Conserved Sequence; Esterification; Gene Deletion; Gene Expression; Humans; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation, Missense; Promoter Regions, Genetic; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Sterol O-Acyltransferase; Structure-Activity Relationship; Transfection; Tryptophan; Tyrosine | 2001 |
Catalase-peroxidase from synechocystis is capable of chlorination and bromination reactions.
Topics: Alanine; Bacterial Proteins; Bromine; Catalase; Chlorine; Cyanobacteria; Electrons; Escherichia coli Proteins; Hydrogen Peroxide; Hydrogen-Ion Concentration; Iodine; Models, Chemical; Mutagenesis, Site-Directed; Peroxidase; Peroxidases; Phenylalanine; Protein Binding; Recombinant Proteins; Time Factors; Tryptophan | 2001 |
Difference in cholesterol-binding and cytolytic activities between listeriolysin O and seeligeriolysin O: a possible role of alanine residue in tryptophan-rich undecapeptide.
Topics: Alanine; Animals; Bacterial Toxins; Cholesterol; Heat-Shock Proteins; Hemolysin Proteins; Hemolysis; Listeria; Listeria monocytogenes; Mutation; Peptides; Recombinant Proteins; Sheep; Tryptophan | 2001 |
Investigation of the dNTP-binding site of HIV-1 reverse transcriptase using photoreactive analogs of dNTP.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Catalytic Domain; Deoxyuracil Nucleotides; Dideoxynucleotides; HIV Reverse Transcriptase; Kinetics; Magnesium; Manganese; Photoaffinity Labels; Photochemistry; Tryptophan; Tyrosine; Ultraviolet Rays; Uracil Nucleotides | 2001 |
Anchoring of surface proteins to the cell wall of Staphylococcus aureus. Cysteine 184 and histidine 120 of sortase form a thiolate-imidazolium ion pair for catalysis.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Aminoacyltransferases; Bacterial Proteins; Binding Sites; Catalysis; Cell Wall; Cysteine; Cysteine Endopeptidases; Histidine; Hydrolysis; Imidazoles; Ions; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Peptides; Plasmids; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Staphylococcus aureus; Sulfhydryl Compounds; Time Factors; Tryptophan | 2002 |
Effect of mutation of a calmodulin binding site on Ca2+ regulation of inositol trisphosphate receptors.
Topics: Alanine; Amino Acid Substitution; Animals; Binding Sites; Calcium; Calcium Channels; Calmodulin; COS Cells; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Microsomes; Mutagenesis, Site-Directed; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Transfection; Tryptophan | 2001 |
Recognition of cello-oligosaccharides by a family 17 carbohydrate-binding module: an X-ray crystallographic, thermodynamic and mutagenic study.
Topics: Alanine; Binding Sites; Calorimetry; Cellulase; Cellulose; Clostridium; Crystallography, X-Ray; Hydrogen Bonding; Ligands; Models, Molecular; Mutation; Oligosaccharides; Protein Binding; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Static Electricity; Substrate Specificity; Tetroses; Thermodynamics; Titrimetry; Trioses; Tryptophan | 2001 |
Structural studies of porcine myeloid antibacterial peptide PMAP-23 and its analogues in DPC micelles by NMR spectroscopy.
Topics: Alanine; Amino Acid Sequence; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Arginine; Circular Dichroism; Leukocytes; Lipid Bilayers; Magnetic Resonance Spectroscopy; Micelles; Models, Molecular; Molecular Sequence Data; Peptide Biosynthesis; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Structure-Activity Relationship; Swine; Tryptophan | 2002 |
Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor.
Topics: Alanine; Allosteric Site; Arginine; Bacterial Proteins; Crystallography, X-Ray; DNA; Escherichia coli; Escherichia coli Proteins; Hypoxanthine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Repressor Proteins; Tryptophan | 2002 |
Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner.
Topics: Alanine; Alcohols; Amino Acid Motifs; Amino Acids; Animals; Blotting, Western; Dose-Response Relationship, Drug; Glutamic Acid; Glutamine; Leucine; Oocytes; Phosphorylation; Protein Binding; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Time Factors; Tryptophan; Xenopus laevis | 2002 |
Essential hydrophilic carboxyl-terminal regions including cysteine residues of the yeast stretch-activated calcium-permeable channel Mid1.
Topics: Alanine; Alleles; Asparagine; Binding Sites; Calcium; Calcium Channels; Codon; Codon, Nonsense; Cysteine; Fungal Proteins; Hydroxylamine; Immunoblotting; Membrane Glycoproteins; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine; Time Factors; Tryptophan; Two-Hybrid System Techniques | 2002 |
Chimaeric gonadotropin-releasing hormone (GnRH) peptides with improved affinity for the catfish (Clarias gariepinus) GnRH receptor.
Topics: Alanine; Animals; Aspartic Acid; Binding Sites; Catfishes; Cell Line; Cell Membrane; Chickens; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Gonadotropin-Releasing Hormone; Humans; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Peptides; Protein Binding; Protein Structure, Tertiary; Receptors, LHRH; Recombinant Fusion Proteins; Transfection; Tryptophan; Tyrosine | 2002 |
Hydration effects of heparin on antithrombin probed by osmotic stress.
Topics: Alanine; Antithrombins; Asparagine; Binding Sites; Heparin; Isoleucine; Kinetics; Leucine; Models, Molecular; Osmotic Pressure; Protein Binding; Serine; Spectrometry, Fluorescence; Thermodynamics; Threonine; Time Factors; Tryptophan; Valine; Water; X-Rays | 2002 |
PPARgamma2 pro12Ala polymorphism and insulin resistance in Japanese hypertensive patients.
Topics: Adult; Alanine; Alleles; Amino Acid Substitution; Arginine; Asian People; Gene Frequency; Genotype; Humans; Hypertension; Insulin Resistance; Japan; Male; Middle Aged; Polymorphism, Genetic; Proline; Receptors, Adrenergic, beta; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tryptophan | 2002 |
Probing the role of the F-helix in serpin stability through a single tryptophan substitution.
Topics: Alanine; alpha 1-Antitrypsin; Amino Acid Sequence; Amino Acid Substitution; Drug Stability; Guanidine; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Protein Structure, Secondary; Recombinant Proteins; Serpins; Spectrometry, Fluorescence; Tryptophan | 2002 |
Substitutions of Phe61 located in the vicinity of template 5'-overhang influence polymerase fidelity and nucleoside analog sensitivity of HIV-1 reverse transcriptase.
Topics: Adenosine Triphosphate; Alanine; Base Pair Mismatch; Dimerization; DNA; HIV Reverse Transcriptase; Inhibitory Concentration 50; Kinetics; Leucine; Mutagenesis; Mutation; Phenotype; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Thymine Nucleotides; Tryptophan; Tyrosine | 2002 |
Re-engineering butyrylcholinesterase as a cocaine hydrolase.
Topics: Alanine; Amino Acid Substitution; Animals; Butyrylcholinesterase; CHO Cells; Cocaine; Cricetinae; Genetic Engineering; Hydrolases; Models, Molecular; Tryptophan; Tyrosine | 2002 |
Synthesis of a 2-arylsulphonylated tryptophan: the antibacterial activity of bovine lactoferricin peptides containing Trp(2-Pmc).
Topics: Alanine; Animals; Anti-Bacterial Agents; Cattle; Escherichia coli; Indoles; Lactoferrin; Microbial Sensitivity Tests; Molecular Structure; Peptides; Staphylococcus aureus; Tryptophan | 2002 |
Cerebrospinal fluid glutamine, tryptophan, and tryptophan metabolite concentrations in dogs with portosystemic shunts.
Topics: Alanine; Animals; Dietary Proteins; Dog Diseases; Dogs; Female; Glutamine; Hepatic Encephalopathy; Hydroxyindoleacetic Acid; Male; Portal System; Quinolinic Acid; Serine; Tryptophan | 2002 |
Geometry and intrinsic tilt of a tryptophan-anchored transmembrane alpha-helix determined by (2)H NMR.
Topics: Alanine; Biophysical Phenomena; Biophysics; Cell Membrane; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Models, Theoretical; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Tryptophan | 2002 |
Assessment of enamelysin (MMP-20) selectivity to three peptide bonds on amelogenin sequence.
Topics: Alanine; Amelogenesis; Amelogenin; Amino Acid Sequence; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Dental Enamel; Dental Enamel Proteins; Hydrolysis; Leucine; Matrix Metalloproteinase 20; Matrix Metalloproteinases; Methionine; Peptide Mapping; Proline; Protein Folding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Proteins; Serine; Statistics as Topic; Substrate Specificity; Swine; Time Factors; Tooth Calcification; Tryptophan | 2002 |
Substrate-induced conformational transition in human phenylalanine hydroxylase as studied by surface plasmon resonance analyses: the effect of terminal deletions, substrate analogues and phosphorylation.
Topics: Alanine; Catalytic Domain; Cyclic AMP-Dependent Protein Kinases; Humans; Phenylalanine; Phenylalanine Hydroxylase; Phosphorylation; Protein Conformation; Sequence Deletion; Serine; Spectrometry, Fluorescence; Surface Plasmon Resonance; Tryptophan | 2003 |
Amino acid content of cell cultures infected with Cowdria ruminantium propagated in a protein-free medium.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Bacteriological Techniques; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media, Serum-Free; Ehrlichia ruminantium; Glutamine; Glycine; Heartwater Disease; Proline; Ruminants; Serine; Tryptophan | 2002 |
Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1.
Topics: Adenosine Triphosphate; Alanine; Algorithms; Cations; Cell Line; Cell Membrane; Genetic Vectors; Green Fluorescent Proteins; Humans; Immunoblotting; Ion Transport; Ions; Leukotriene C4; Luminescent Proteins; Microscopy, Confocal; Models, Biological; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Transport; Recombinant Fusion Proteins; Substrate Specificity; Time Factors; Transfection; Tryptophan | 2002 |
Role of protein and substrate dynamics in catalysis by Pseudomonas putida cytochrome P450cam.
Topics: Adamantane; Alanine; Amino Acid Substitution; Camphanes; Camphor; Camphor 5-Monooxygenase; Catalysis; Fluorescence Polarization; Fluorescence Resonance Energy Transfer; Norbornanes; Pseudomonas putida; Recombinant Proteins; Substrate Specificity; Thermodynamics; Tryptophan; Tyrosine | 2002 |
Biotin sulfoxide reductase: Tryptophan 90 is required for efficient substrate utilization.
Topics: Alanine; Escherichia coli; Guanine Nucleotides; Iron-Sulfur Proteins; Isoenzymes; Molybdenum; Mutagenesis, Site-Directed; Oxidoreductases; Phenylalanine; Pterins; Recombinant Fusion Proteins; Rhodobacter sphaeroides; Tryptophan; Tyrosine | 2003 |
Use of intein-directed peptide biosynthesis to improve serum stability and bioactivity of a gelatinase inhibitory peptide.
Topics: Alanine; Amino Acid Sequence; Cell Movement; Drug Stability; Enzyme Inhibitors; Gelatinases; Humans; Mutagenesis, Insertional; Peptide Library; Peptides; Protein Splicing; Recombinant Fusion Proteins; Tryptophan; Tumor Cells, Cultured | 2003 |
Engineered fibronectin type III domain with a RGDWXE sequence binds with enhanced affinity and specificity to human alphavbeta3 integrin.
Topics: Alanine; Antibodies, Monoclonal; Biotinylation; Cell Adhesion; DNA Primers; Enzyme-Linked Immunosorbent Assay; Fibronectins; Flow Cytometry; Glutamic Acid; Humans; In Vitro Techniques; Integrin alphaVbeta3; Kinetics; Molecular Conformation; Oligopeptides; Peptide Fragments; Peptide Library; Plasmids; Polymerase Chain Reaction; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Substrate Specificity; Tryptophan; Tumor Cells, Cultured | 2003 |
Retroevolution of lambda Cro toward a stable monomer.
Topics: Alanine; Amino Acid Sequence; Circular Dichroism; Databases as Topic; Dimerization; DNA-Binding Proteins; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Repressor Proteins; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Temperature; Thermodynamics; Tryptophan; Ultracentrifugation; Viral Proteins; Viral Regulatory and Accessory Proteins | 2003 |
Mechanism of flavin mononucleotide cofactor binding to the Desulfovibrio vulgaris flavodoxin. 1. Kinetic evidence for cooperative effects associated with the binding of inorganic phosphate and the 5'-phosphate moiety of the cofactor.
Topics: Alanine; Apoproteins; Asparagine; Binding Sites; Desulfovibrio vulgaris; Flavin Mononucleotide; Flavodoxin; Histidine; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Phosphates; Protein Binding; Riboflavin; Spectrometry, Fluorescence; Thermodynamics; Threonine; Tryptophan; Tyrosine | 2003 |
Photoacoustic spectroscopy study of neodymium complexes with alanine, valine, phenylalanine and tryptophan.
Topics: Absorption; Acoustics; Alanine; Electrons; Ions; Lanthanoid Series Elements; Ligands; Models, Statistical; Neodymium; Phenylalanine; Spectrophotometry; Tryptophan | 2003 |
A single surface tryptophan in the chitin-binding domain from Bacillus circulans chitinase A1 plays a pivotal role in binding chitin and can be modified to create an elutable affinity tag.
Topics: Alanine; Amino Acid Sequence; Bacillus; Chitin; Chitinases; Electrophoresis, Polyacrylamide Gel; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Osmolar Concentration; Phenylalanine; Plasmids; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Alignment; Tryptophan | 2003 |
Interfacial anchor properties of tryptophan residues in transmembrane peptides can dominate over hydrophobic matching effects in peptide-lipid interactions.
Topics: Alanine; Circular Dichroism; Leucine; Lipid Bilayers; Lysine; Magnetic Resonance Spectroscopy; Membrane Proteins; Models, Chemical; Peptide Fragments; Phosphatidylcholines; Protein Structure, Secondary; Tryptophan | 2003 |
Ultrasonic absorption in aqueous solutions of amino acids at neutral pH.
Topics: Absorption; Alanine; Amino Acids; Glycine; Histidine; Humans; Hydrogen-Ion Concentration; Imidazoles; Phenylalanine; Solutions; Tryptophan; Ultrasonics | 2003 |
Asp274 and his346 are essential for heme binding and catalytic function of human indoleamine 2,3-dioxygenase.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Blotting, Western; Catalysis; Cell Division; Circular Dichroism; Cytokines; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Heme; Histidine; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kinetics; Ligands; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Binding; Protein Conformation; Rats; Sequence Homology, Amino Acid; Tryptophan; Tryptophan Oxygenase; Ultraviolet Rays; Up-Regulation | 2003 |
Kinetic mechanism of the GCN5-related chromosomal aminoglycoside acetyltransferase AAC(6')-Ii from Enterococcus faecium: evidence of dimer subunit cooperativity.
Topics: Acetyltransferases; Alanine; Calorimetry; Diffusion; Dimerization; Dose-Response Relationship, Drug; Enterococcus faecium; Escherichia coli; Kinetics; Models, Chemical; Multigene Family; Mutation; Protein Binding; Protein Structure, Tertiary; Solvents; Thermodynamics; Tryptophan | 2003 |
Experimental tests of villin subdomain folding simulations.
Topics: Alanine; Carrier Proteins; Computer Simulation; Fluorescence; Kinetics; Microfilament Proteins; Models, Molecular; Phenylalanine; Protein Conformation; Protein Folding; Temperature; Thermodynamics; Tryptophan | 2003 |
Alanine prevents the inhibition of pyruvate kinase activity caused by tryptophan in cerebral cortex of rats.
Topics: Alanine; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Nerve Tissue Proteins; Pyruvate Kinase; Rats; Rats, Wistar; Tryptophan | 2003 |
Molecular determinants of the balance between co-repressor and co-activator recruitment to the retinoic acid receptor.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Cell Line; DNA Mutational Analysis; Glutathione Transferase; Haplorhini; Ligands; Luciferases; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Transcription, Genetic; Transfection; Tryptophan | 2003 |
The nutrition of animal tissues cultivated in vitro. IV. Amino acid requirements of chick embryonic heart fibroblasts.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Fibroblasts; Glycine; Histidine; Hydroxyproline; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
The amino acid requirements of rabbit fibroblasts, strain RM3-56.
Topics: Alanine; Amino Acids; Animals; Arginine; Cystine; Fibroblasts; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Rabbits; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
Amino acids as gustatory stimuli in the rat.
Topics: Alanine; Amino Acids; Animals; Chorda Tympani Nerve; Glycine; Methionine; Rats; Sodium Chloride; Taste; Tryptophan | 1962 |
Interaction of amino-acids with riboflavin.
Topics: Alanine; Amino Acids; Glycine; Leucine; Phenylalanine; Riboflavin; Tryptophan | 1963 |
[Thin layer chromatographic separation of amino acids on cellulose layers].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Methionine; Serine; Tryptophan; Tyrosine; Valine | 1962 |
The specific chemical sensitivity of Helix nerve cells.
Topics: Acetylcholine; Alanine; Amino Acids; Animals; Dopamine; Ganglia; Glutamates; Helix, Snails; Histamine; Neurons; Phenylalanine; Serotonin; Snails; Tryptophan | 1962 |
The antihistaminic action of normal human blood constituents and tissue biolytes.
Topics: Alanine; Erythrocytes; Gastric Juice; Guanidines; Humans; Ileum; Intestinal Secretions; Leucine; Methionine; Tryptophan | 1962 |
[RESEARCH ON THE NUTRITION OF ERWINIA CAROTOVORA].
Topics: Alanine; Aminobutyrates; Ammonium Compounds; Arginine; Asparagine; Aspartic Acid; Boron; Calcium; Cobalt; Copper; Creatine; Creatinine; Culture; Culture Media; Cysteine; Cystine; Erwinia; Glutamates; Glycine; Iron; Lysine; Magnesium; Manganese; Methionine; Minerals; Molybdenum; Pectobacterium carotovorum; Proteins; Quaternary Ammonium Compounds; Tryptophan; Tyrosine; Zinc | 1963 |
THE AMINO ACID SEQUENCE OF ILAMYCIN AND ILAMYCIN B.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Leucine; Research; Tryptophan | 1963 |
A NEW METHOD FOR QUANTITATIVE PAPER CHROMATOGRAPHY.
Topics: Alanine; Ascorbic Acid; Chromatography; Chromatography, Paper; Colorimetry; Creatine; Creatinine; Ephedrine; Iodides; Iodine; Malonates; Pilocarpine; Research; Tryptophan | 1963 |
N-ACETYLAMINO ACIDS AND PROTEIN SYNTHESIS.
Topics: Alanine; Glutamates; Histidine; Liver; Proteins; Research; RNA; Tryptophan; Tyrosine | 1963 |
GAS CHROMATOGRAPHY OF AMINO ACIDS. 1. ANALYSIS OF THE MIXTURE OF METHYL-NTRIFLUOROACETYL DERIVATIVES.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography; Chromatography, Gas; Fluoroacetates; Glutamates; Glycine; Hydroxyproline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1963 |
EFFECT OF TRICHINELLA SPIRALIS INFECTION ON INCORPORATION OF AMINO ACIDS INTO SERUM AND HEMOGLOBIN.
Topics: Alanine; Amino Acids; Animals; Blood Proteins; Carbon Isotopes; Glycine; Hemoglobins; Mice; Research; Trichinella spiralis; Trichinellosis; Tryptophan; Tyrosine | 1963 |
AMINOPEPTIDASE OF THE OCULAR LENS. II. SUBSTRATE SPECIFICITY.
Topics: Alanine; Aminopeptidases; Cobalt; Glutamine; Ions; Kidney; Lens, Crystalline; Leucine; Magnesium; Manganese; Naphthalenes; Research; Substrate Specificity; Tryptophan | 1963 |
THE SOLUBILITY OF AMINO ACIDS AND RELATED COMPOUNDS IN AQUEOUS UREA SOLUTIONS.
Topics: Alanine; Amino Acids; Asparagine; Chemical Phenomena; Chemistry; Glutamine; Glycine; Histidine; Leucine; Methionine; Peptides; Phenylalanine; Research; Solubility; Solvents; Spectrophotometry; Threonine; Tryptophan; Tyrosine; Urea | 1963 |
THE INHIBITION OF CEREBRAL DIGLYCINASE BY ALPHA-AMINO-, ALPHA-KETO- AND ALPHA-HYDROXY ACIDS.
Topics: Alanine; Aminobutyrates; Animals; Arginine; Aspartic Acid; Brain; Cobalt; Enzyme Inhibitors; Histidine; Hydroxy Acids; Keto Acids; Leucine; Methionine; Mice; Peptide Hydrolases; Peptides; Pharmacology; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Valine | 1963 |
[QUANTITATIVE STUDY OF THE FATE OF AMINO ACIDS UNDER THE INFLUENCE OF THE FREE HYDROXYL RADICAL].
Topics: Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Biochemical Phenomena; Biochemistry; Carbon Isotopes; Chromatography; Glutamates; Hydroxides; Hydroxyl Radical; Phenylalanine; Research; Serine; Tryptophan | 1963 |
STUDIES ON MORPHINE. IV. EFFECTS OF SOME METABOLITES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
Topics: Alanine; Cyanides; Fluoroacetates; Glutamine; Iodoacetates; Mice; Morphine; NAD; Nalorphine; Niacin; Niacinamide; Pharmacology; Pyridines; Pyridoxine; Research; Serine; Toxicology; Tryptophan | 1963 |
INFLUENCE OF AMINO ACIDS ON RAT LIVER PHENYLALANINE HYDROXYLASE ACTIVITY.
Topics: Alanine; Amides; Amino Acids; Blood Chemical Analysis; Citrates; Glycine; Leucine; Liver; Metabolism; Mixed Function Oxygenases; Phenylalanine; Phenylalanine Hydroxylase; Rats; Research; Tryptophan; Tyrosine | 1964 |
MIGRATION OF AMINO ACIDS ACROSS THE MEMBRANE OF THE HUMAN ERYTHROCYTE.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport; Carbon Isotopes; Erythrocytes; Glycine; Histidine; Leucine; Methionine; Permeability; Phenylalanine; Proteins; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
DYNAMIC PHENOMENA IN MICROSPHERES FROM THERMAL PROTEINOID.
Topics: Alanine; Arginine; Aspartic Acid; Colloids; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Microspheres; Peptides; Phenylalanine; Photomicrography; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
[SEPARATION OF AMINO ACIDS BY CHROMATOGRAPHY ON THIN LAYERS OF DIETHYLAMINOETHYL CELLULOSE].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
STUDIES ON THE SPECIFICITY OF TYROSINE-ALPHA-KETOGLUTARATE TRANSAMINASE.
Topics: 5-Hydroxytryptophan; Alanine; Amphetamine; Benzoates; Butyrates; Catecholamines; Dihydroxyphenylalanine; Enzyme Inhibitors; Ephedrine; Indoleacetic Acids; Ketoglutaric Acids; Lactates; Liver; Mandelic Acids; Methyldopa; Normetanephrine; Pharmacology; Phenylacetates; Phenylalanine; Propionates; Rats; Research; Transaminases; Tryptophan; Tyramine; Tyrosine; Tyrosine Transaminase | 1964 |
[FREE AMINO ACIDS IN THE BLOOD AND URINE OF PATIENTS WITH SOME FORMS OF DERMATOSIS].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Blood; Cystine; Dermatitis; Eczema; Erythema Multiforme; Glutamates; Glycine; Histidine; Lupus Erythematosus, Systemic; Lysine; Proteins; Psoriasis; Renal Aminoacidurias; Serine; Skin Diseases; Taurine; Threonine; Toxicology; Tryptophan; Urticaria | 1964 |
A SIMPLE PREPARATION METHOD FOR DIPHOSPHOMIDAZOLE.
Topics: Alanine; Amides; Calcium Phosphates; Chlorides; Chromatography; Cysteine; Cystine; Glycine; Histidine; Imidazoles; Ion Exchange Resins; Methionine; Phosphates; Phosphorus; Research; Serine; Tryptophan; Tyrosine | 1964 |
[ON THE COLORIMETRY OF ALPHA-AMINO ACIDS AND PRIMARY AMINES WITH THE AID OF ASCORBIC ACID].
Topics: Alanine; Amines; Amino Acids; Ammonia; Ascorbic Acid; Colorimetry; Ethylamines; Glutamates; Glycine; Histidine; Lysine; Methionine; Research; Spectrophotometry; Threonine; Tryptophan | 1964 |
INTERACTIONS OF PURINE WITH PROTEINS AND AMINO ACIDS.
Topics: Alanine; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Glycine; Histidine; Hot Temperature; Muramidase; Phenylalanine; Proteins; Purines; Research; Ribonucleases; Serum Albumin; Serum Albumin, Bovine; Tryptophan; Tyrosine | 1964 |
AMINO ACID COMPOSITION OF BULK PROTEIN OF EUGLENA GROWN IN WASTE WATER.
Topics: Alanine; Amino Acids; Animals; Euglena; Histidine; Methionine; Proline; Proteins; Research; Sewage; Threonine; Tryptophan; Valine; Wastewater | 1964 |
ELECTRONIC EFFECTS AND L-AMINO-ACID OXIDASE SPECIFICITY.
Topics: Alanine; Amino Acid Oxidoreductases; Amino Acids; L-Amino Acid Oxidase; Leucine; Phenylacetates; Phenylalanine; Research; Snakes; Tryptophan; Tyrosine; Venoms | 1964 |
THE SYNTHESIS AND METABOLISM OF DL-TRYPTOPHAN-5-14C.
Topics: Acetates; Alanine; Amino Acids; Anilides; Benzoates; Glutamates; Glutarates; Lipid Metabolism; Liver; Liver Glycogen; Nucleic Acids; ortho-Aminobenzoates; Protein Hydrolysates; Rats; Research; Tryptophan | 1964 |
A NEW HAEMOGLOBIN-JA OXFORD FOUND DURING A SURVEY OF AN ENGLISH POPULATION.
Topics: Alanine; Aspartic Acid; Chromatography; Electrophoresis; England; Glycine; Hemoglobins; Hemoglobins, Abnormal; Lysine; Peptides; Tryptophan | 1964 |
AMINO ACIDS AS PROTECTIVE COMPOUNDS IN ULTRAVIOLET-IRRADIATED HANSENULA WINGEI.
Topics: Alanine; Amino Acids; Arginine; Cysteine; Cystine; Ethionine; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Pichia; Proline; Radiation-Protective Agents; Research; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays; Valine; Yeasts | 1964 |
BREAKDOWN OF AMINO ACIDS BY ENTEROBACTERIACEAE. II. STEREOSPECIFICITY OF ALKALIZATION REACTION.
Topics: Alanine; Amino Acids; Enterobacteriaceae; Glutamates; Histidine; Research; Serine; Tryptophan; Valine | 1964 |
[DEGRADATION OF TRYPTOPHAN BY ESCHERICHIA COLI. II. INDIRECT METHODS].
Topics: Alanine; Escherichia coli; Glycine; Indoleacetic Acids; Indoles; Metabolism; Research; Serine; Tryptophan | 1964 |
THE MAJOR ALKALINE PROTEINASE OF ASPERGILLUS ORYZAE, ASPERGILLOPEPTIDASE B. II. PARTIAL SPECIFIC VOLUME, MOLECULAR WEIGHT, AND AMINO ACID COMPOSITION.
Topics: Alanine; Amides; Amino Acids; Aspergillus; Aspergillus oryzae; Bacterial Proteins; Buffers; Chemical Phenomena; Chemistry, Physical; Cysteine; Cystine; Densitometry; Endopeptidases; Glycine; Molecular Weight; Nitrogen; Peptide Hydrolases; Research; Serine; Serine Endopeptidases; Tryptophan | 1964 |
FALSE FEEDBACK INHIBITION OF AROMATIC AMINO ACID BIOSYNTHESIS BY BETA-2-THIENYLALANINE.
Topics: Alanine; Amino Acids; Amino Acids, Aromatic; Escherichia coli; Feedback; Ligases; Metabolism; Mutation; Pharmacology; Phenylalanine; Proteins; Research; RNA; Shikimic Acid; Thiophenes; Tryptophan; Tyrosine | 1965 |
RAT LIVER ENZYME DOES NOT ACTIVATE ACETYLAMINO ACIDS.
Topics: Acetates; Adenosine Triphosphate; Alanine; Amino Acids; Arginine; Diphosphates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Liver; Lysine; Methionine; Phenylalanine; Proline; Rats; Research; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
EFFECT OF AMINO ACIDS ON GROWTH OF SPHAEROTILUS DISCOPHORUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Bacteriological Techniques; Caseins; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Proline; Research; Serine; Sphaerotilus; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
OPHIDIAN L-AMINO ACID OXIDASE. THE NATURE OF THE ENZYME-SUBSTRATE COMPLEXES.
Topics: Alanine; Amino Acid Oxidoreductases; Amino Acids; Animals; Biochemical Phenomena; Biochemistry; Catalysis; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Glycine; Hydroquinones; Kinetics; L-Amino Acid Oxidase; Phenylalanine; Research; Snakes; Tryptophan; Venoms | 1965 |
RECENT DEVELOPMENTS IN THE UNDERSTANDING OF AMINO-ACID AND PROTEIN METABOLISM BY SCHISTOSOMA MANSONI IN VITRO.
Topics: Alanine; Amino Acids; Animals; Arginase; Arginine; Aspartic Acid; Carbon Isotopes; Glucose; Hemoglobins; Histidine; In Vitro Techniques; Ornithine; Peptides; Proline; Proteins; Radiometry; Research; Schistosoma; Schistosoma mansoni; Tryptophan; Urea | 1965 |
Human RNase H1 uses one tryptophan and two lysines to position the enzyme at the 3'-DNA/5'-RNA terminus of the heteroduplex substrate.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Catalysis; Escherichia coli; Humans; Kinetics; Lysine; Models, Biological; Models, Chemical; Molecular Sequence Data; Mutation; Oligonucleotides; Plasmids; Protein Binding; Protein Structure, Tertiary; Ribonuclease H; Sequence Homology, Amino Acid; Time Factors; Tryptophan | 2003 |
Dynamic features of a heme delivery system for cytochrome C maturation.
Topics: Alanine; Amino Acid Motifs; Bacterial Outer Membrane Proteins; Bacterial Proteins; Cell Division; Cytochromes c; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Genotype; Heme; Hemeproteins; Histidine; Membrane Proteins; Models, Biological; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Periplasm; Phenotype; Plasmids; Precipitin Tests; Protein Binding; Subcellular Fractions; Tryptophan | 2003 |
Structural characterization of the peroxodiiron(III) intermediate generated during oxygen activation by the W48A/D84E variant of ribonucleotide reductase protein R2 from Escherichia coli.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Escherichia coli Proteins; Ferric Compounds; Ferrous Compounds; Glutamic Acid; Oxygen; Oxygenases; Protein Subunits; Ribonucleotide Reductases; Spectroscopy, Mossbauer; Spectrum Analysis; Tryptophan; X-Rays | 2003 |
Effect of pH on the oxidation-reduction properties of thioredoxins.
Topics: Alanine; Animals; Aspartic Acid; Binding Sites; Chlamydomonas reinhardtii; Cysteine; Disulfides; Electron Transport; Escherichia coli Proteins; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Oxidation-Reduction; Protons; Thioredoxin h; Thioredoxins; Tryptophan | 2003 |
Mutation of cysteine 214 in Gi1 alpha subunit abolishes its endogenous GTPase activity.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Alanine; Amino Acid Substitution; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cysteine; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Triphosphate; Hydrolysis; Kinetics; Mutation; Pertussis Toxin; Protein Binding; Protein Subunits; RGS Proteins; Thermodynamics; Trypsin; Tryptophan | 2004 |
Influence of the polymorphisms Tpr64Arg in the beta 3-adrenergic receptor gene and Pro12Ala in the PPAR gamma 2 gene on metabolic syndrome-related phenotypes in an indigenous population of the Brazilian Amazon.
Topics: Alanine; Arginine; Brazil; Female; Humans; Male; Metabolic Syndrome; Obesity; Phenotype; Polymorphism, Single Nucleotide; Proline; Racial Groups; Receptors, Adrenergic, beta-3; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tryptophan | 2004 |
Nitrogen metabolism in the African lungfish (Protopterus dolloi) aestivating in a mucus cocoon on land.
Topics: Africa; Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Estivation; Fishes; Glutamic Acid; Time Factors; Tryptophan | 2004 |
DL- beta-3-oxindolylalanine (DL-hydroxytryptophan). 1. Synthesis.
Topics: 5-Hydroxytryptophan; Alanine; Oxindoles; Tryptophan | 1951 |
Beta-3-oxindolylalanine (hydroxytryptophan). 2. Spectroscopic and chromatographic properties.
Topics: 5-Hydroxytryptophan; Alanine; Oxindoles; Tryptophan | 1951 |
Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands.
Topics: Alanine; Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cycloserine; Databases as Topic; Escherichia coli; Excitatory Amino Acid Antagonists; Glycine; Humans; Hydrogen Bonding; Indoles; Kynurenic Acid; Ligands; Mice; Models, Chemical; Models, Molecular; Molecular Sequence Data; Potassium Channels; Proline; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sequence Homology, Amino Acid; Serine; Threonine; Tryptophan; Water | 2004 |
Contributions of amino acid side chains to the kinetics and thermodynamics of the bivalent binding of protein L to Ig kappa light chain.
Topics: Alanine; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Chromatography, Gel; Computational Biology; Computer Simulation; Dimerization; Disulfides; DNA-Binding Proteins; Humans; Immunoglobulin kappa-Chains; Immunoglobulin Variable Region; Kinetics; Mutagenesis, Site-Directed; Protein Binding; Radioimmunoassay; Spectrometry, Fluorescence; Surface Plasmon Resonance; Thermodynamics; Time Factors; Tryptophan; Tyrosine | 2004 |
In vivo properties of thiol inhibitors of the three vasopeptidases NEP, ACE and ECE are improved by introduction of a 7-azatryptophan in P2' position.
Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartic Acid Endopeptidases; Endothelin-Converting Enzymes; Indans; Male; Metalloendopeptidases; Molecular Structure; Neprilysin; Peptidyl-Dipeptidase A; Protease Inhibitors; Rats; Rats, Wistar; Structure-Activity Relationship; Sulfhydryl Compounds; Tryptophan; Vascular Diseases | 2004 |
Trp2063 and Trp2064 in the factor Va C2 domain are required for high-affinity binding to phospholipid membranes but not for assembly of the prothrombinase complex.
Topics: Alanine; Amino Acid Substitution; Animals; Cattle; Cell Line; COS Cells; Factor Va; Fluorescence Resonance Energy Transfer; Humans; Lipid Bilayers; Moths; Phosphatidylserines; Phospholipids; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Proteins; Surface Plasmon Resonance; Thromboplastin; Tryptophan | 2004 |
Cysteine repeat domains and adjacent sequences determine distinct bone morphogenetic protein modulatory activities of the Drosophila Sog protein.
Topics: Alanine; Amino Acid Motifs; Amino Acid Substitution; Animals; Bone Morphogenetic Proteins; Cysteine; Drosophila; Drosophila Proteins; Gene Expression Regulation, Developmental; Genes, Insect; Ligands; Microinjections; Point Mutation; Protein Structure, Tertiary; RNA; Sequence Deletion; Structure-Activity Relationship; Tryptophan; Wings, Animal; Xenopus | 2004 |
Receptor internalization-independent activation of Smad2 in activin signaling.
Topics: Activins; Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Chlorocebus aethiops; COS Cells; DNA-Binding Proteins; Molecular Sequence Data; Phosphorylation; Point Mutation; Potassium; Promoter Regions, Genetic; Proteins; Signal Transduction; Smad2 Protein; Trans-Activators; Tryptophan | 2004 |
Formation of a semiquinone at the QB site by A- or B-branch electron transfer in the reaction center from Rhodobacter sphaeroides.
Topics: Alanine; Anti-Bacterial Agents; Benzoquinones; Binding Sites; Electron Transport; Freezing; Light; Mutagenesis, Site-Directed; Oxidation-Reduction; Photosynthetic Reaction Center Complex Proteins; Polyenes; Rhodobacter sphaeroides; Spectroscopy, Fourier Transform Infrared; Tryptophan; Ubiquinone | 2004 |
The stereospecificity and catalytic efficiency of the tryptophan synthase-catalysed exchange of the alpha-protons of amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Catalysis; Deuterium; Glycine Hydroxymethyltransferase; Hydrogen; Kinetics; Norleucine; Nuclear Magnetic Resonance, Biomolecular; Predictive Value of Tests; Protons; Serine; Stereoisomerism; Substrate Specificity; Tryptophan; Tryptophan Synthase; Valine | 2004 |
Tryptophan 621 and serine 667 residues of Daxx regulate its nuclear export during glucose deprivation.
Topics: Active Transport, Cell Nucleus; Alanine; Antibiotics, Antineoplastic; Binding Sites; Cell Line, Tumor; Exportin 1 Protein; Fatty Acids, Unsaturated; Genetic Vectors; Glucose; Humans; Immunoblotting; Karyopherins; Male; Models, Biological; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Prostatic Neoplasms; Protein Binding; Receptors, Cytoplasmic and Nuclear; Serine; Time Factors; Tryptophan | 2004 |
Mutation of the surface-exposed amino acid Trp to Ala in the FVIII C2 domain results in defective secretion of the otherwise functional protein.
Topics: Alanine; Blotting, Western; Cell Line; Electrophoresis, Polyacrylamide Gel; Factor VIII; Factor Xa; Humans; Mutation; Protein Binding; Protein Structure, Tertiary; Tryptophan; von Willebrand Factor | 2004 |
Interaction of 7-azatryptophan and beta-(1-azulenyl)-alanine with a nitroxyl radical.
Topics: Alanine; Electron Spin Resonance Spectroscopy; Free Radicals; In Vitro Techniques; Molecular Structure; Nitrogen Oxides; Oligopeptides; Spin Labels; Tryptophan | 2003 |
Functional dissection and molecular characterization of calcium-sensitive actin-capping and actin-depolymerizing sites in villin.
Topics: Actins; Alanine; Aspartic Acid; Binding Sites; Calcium; Cloning, Molecular; DNA Mutational Analysis; Dose-Response Relationship, Drug; Escherichia coli; Gelsolin; Humans; Kinetics; Magnetic Resonance Spectroscopy; Microfilament Proteins; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Thermodynamics; Time Factors; Tryptophan; Urea | 2004 |
Alanine-scanning mutagenesis in the signature disulfide loop of the glycine receptor alpha 1 subunit: critical residues for activation and modulation.
Topics: Alanine; Allosteric Regulation; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Cell Line; Conserved Sequence; Cysteine; Disulfides; Humans; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Proline; Protein Structure, Tertiary; Protein Subunits; Receptors, Glycine; Tryptophan | 2004 |
Ionic interactions near the loop L4 are important for maintaining the active-site environment and the dimer stability of (pro)caspase 3.
Topics: Alanine; Binding Sites; Caspase 3; Caspases; Catalysis; Chromatography, Gel; Circular Dichroism; Dimerization; Enzyme Precursors; Enzyme Stability; Fluorescence; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutation; Protein Processing, Post-Translational; Static Electricity; Thermodynamics; Tryptophan | 2004 |
Antimicrobial activity of arginine- and tryptophan-rich hexapeptides: the effects of aromatic clusters, D-amino acid substitution and cyclization.
Topics: Alanine; Amino Acid Motifs; Anti-Infective Agents; Antimicrobial Cationic Peptides; Arginine; Bacillus subtilis; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Erythrocytes; Escherichia coli; Hemolysis; Humans; Lipid Bilayers; Peptides; Protein Conformation; Tryptophan | 2004 |
Direct probing of zwitterion formation in unsolvated peptides.
Topics: Alanine; Models, Molecular; Peptides; Protein Conformation; Thermodynamics; Tryptophan | 2003 |
Long-range dynamic effects of point mutations propagate through side chains in the serine protease inhibitor eglin c.
Topics: Alanine; Animals; Leeches; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Nanotechnology; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Point Mutation; Polymerase Chain Reaction; Protein Conformation; Protein Subunits; Proteins; Serine Proteinase Inhibitors; Serpins; Thermodynamics; Tryptophan; Valine | 2004 |
The helical alanine controversy: an (Ala)6 insertion dramatically increases helicity.
Topics: Alanine; Amino Acid Sequence; Circular Dichroism; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Peptides; Protein Structure, Secondary; Thermodynamics; Tryptophan | 2004 |
Supplementation with aromatic amino acids improves leucine kinetics but not aromatic amino acid kinetics in infants with infection, severe malnutrition, and edema.
Topics: Alanine; Amino Acids, Aromatic; Anthropometry; Body Water; Deuterium; Edema; Enteral Nutrition; Humans; Infant; Infections; Intubation, Gastrointestinal; Kinetics; Leucine; Phenylalanine; Protein-Energy Malnutrition; Proteins; Tryptophan; Tyrosine | 2004 |
The Arg64 allele of the beta 3-adrenoceptor gene but not the -3826G allele of the uncoupling protein 1 gene is associated with increased leptin levels in the Spanish population.
Topics: Adipocytes; Adult; Alanine; Arginine; Blood Glucose; Body Mass Index; Carrier Proteins; Cholesterol; Cross-Sectional Studies; Female; Gene Frequency; Genotype; Glycine; Humans; Insulin; Ion Channels; Leptin; Linear Models; Male; Membrane Proteins; Middle Aged; Mitochondrial Proteins; Obesity; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Receptors, Adrenergic, beta-3; Receptors, Leptin; Sex Factors; Spain; Triglycerides; Tryptophan; Uncoupling Protein 1; Waist-Hip Ratio | 2004 |
Strength of integration of transmembrane alpha-helical peptides in lipid bilayers as determined by atomic force spectroscopy.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Alanine; Leucine; Lipid Bilayers; Membrane Proteins; Membranes; Microscopy, Atomic Force; Models, Chemical; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Protein Structure, Tertiary; Tryptophan; Water | 2004 |
A charged amino acid residue in the transmembrane/cytoplasmic region of tapasin influences MHC class I assembly and maturation.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Antiporters; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP Binding Cassette Transporter, Subfamily B, Member 3; ATP-Binding Cassette Transporters; Cell Line, Transformed; Cell Membrane; Cytoplasm; Endoplasmic Reticulum; Heat-Shock Proteins; Histocompatibility Antigens Class I; HLA Antigens; HLA-B8 Antigen; Humans; Immunoglobulins; Isomerases; Lysine; Membrane Transport Proteins; Mice; Molecular Sequence Data; Protein Disulfide-Isomerases; Protein Folding; Protein Processing, Post-Translational; Protein Transport; Tryptophan; Up-Regulation | 2005 |
The phosphatidylserine binding site of the factor Va C2 domain accounts for membrane binding but does not contribute to the assembly or activity of a human factor Xa-factor Va complex.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Enzyme Activation; Factor Va; Factor Xa; Humans; Lipid Bilayers; Peptide Fragments; Phosphatidylserines; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Prothrombin; Recombinant Proteins; Tryptophan | 2005 |
Tryptophan residues flanking the second transmembrane helix (TM2) set the signaling state of the Tar chemoreceptor.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Chemoreceptor Cells; Chemotaxis; Cytoplasm; Escherichia coli; Escherichia coli Proteins; Histidine Kinase; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Methylation; Molecular Sequence Data; Protein Structure, Secondary; Receptors, Cell Surface; Signal Transduction; Tryptophan | 2005 |
Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste.
Topics: Alanine; Animals; Benzene Derivatives; Binding Sites; Cell Line; Cell Membrane; Cysteine; Dose-Response Relationship, Drug; Humans; Ligands; Mice; Models, Chemical; Models, Molecular; Mutation; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Recombinant Fusion Proteins; Taste; Tryptophan | 2005 |
Probing the communication between the regulatory and catalytic domains of a protein tyrosine kinase, Csk.
Topics: Alanine; Animals; Catalytic Domain; Chickens; Crystallography, X-Ray; CSK Tyrosine-Protein Kinase; Enzyme Activation; Phenylalanine; Phosphopeptides; Phosphotyrosine; Point Mutation; Protein Conformation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Sequence Alignment; Sequence Deletion; src Homology Domains; src-Family Kinases; Substrate Specificity; Tryptophan | 2005 |
Probing the environment of signal-anchor sequences during topogenesis in the endoplasmic reticulum.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Chlorocebus aethiops; COS Cells; Endoplasmic Reticulum; Genetic Vectors; Hydrophobic and Hydrophilic Interactions; Intracellular Membranes; Leucine; Lipid Bilayers; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Protein Sorting Signals; Protein Transport; Transfection; Tryptophan; Valine | 2005 |
Switching pyridine nucleotide specificity in P450 BM3: mechanistic analysis of the W1046H and W1046A enzymes.
Topics: Alanine; Amino Acid Substitution; Animals; Bacillus megaterium; Bacterial Proteins; Cytochrome P-450 Enzyme System; Flavin-Adenine Dinucleotide; Histidine; Kinetics; Mixed Function Oxygenases; Mutation; NADP; NADPH-Ferrihemoprotein Reductase; Potentiometry; Protein Structure, Tertiary; Pyridines; Rats; Spectrophotometry; Substrate Specificity; Thermodynamics; Tryptophan | 2005 |
Entropic stabilization of isolated beta-sheets.
Topics: Alanine; Algorithms; Computer Simulation; Models, Molecular; Monte Carlo Method; Peptides; Protein Structure, Secondary; Thermodynamics; Tryptophan | 2005 |
Functional characterization of N-terminal nucleotide binding domain (NBD-1) of a major ABC drug transporter Cdr1p of Candida albicans: uncommon but conserved Trp326 of Walker B is important for ATP binding.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Motifs; ATP-Binding Cassette Transporters; Binding Sites; Bromosuccinimide; Candida albicans; Conserved Sequence; Drug Resistance, Fungal; Fluorescent Dyes; Fungal Proteins; Magnesium; Membrane Transport Proteins; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; Protein Structure, Tertiary; Spectrophotometry; Tryptophan | 2005 |
An essential tryptophan of Escherichia coli DnaA protein functions in oligomerization at the E. coli replication origin.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Motifs; Bacterial Proteins; Cross-Linking Reagents; DNA; DNA Mutational Analysis; DNA-Binding Proteins; Dose-Response Relationship, Drug; Escherichia coli; Glutaral; Leucine; Mutation; Phenylalanine; Plasmids; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Replication Origin; Time Factors; Tryptophan | 2005 |
Phosphorylation of the RGS protein Sst2 by the MAP kinase Fus3 and use of Sst2 as a model to analyze determinants of substrate sequence specificity.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Consensus Sequence; Feedback, Physiological; GTPase-Activating Proteins; Histidine; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phenylalanine; Phosphorylation; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity; Tryptophan | 2005 |
Functional characterization and ATP-induced dimerization of the isolated ABC-domain of the haemolysin B transporter.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; ATP-Binding Cassette Transporters; Bacterial Proteins; Buffers; Carrier Proteins; Dimerization; Escherichia coli Proteins; Hemolysin Proteins; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Models, Chemical; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; Protein Structure, Tertiary; Tryptophan; Tyrosine | 2005 |
Insensitivity of D-amino acid dehydrogenase synthesis to catabolic repression in dadR mutants of Salmonella typhimurium.
Topics: Alanine; D-Amino-Acid Oxidase; Enzyme Repression; Genes, Bacterial; Glucose; Histidine; Methionine; Mutation; Operon; Salmonella typhimurium; Tryptophan | 1975 |
A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study.
Topics: Alanine; Animals; Binding Sites; Crystallography, X-Ray; Dose-Response Relationship, Drug; Electrophysiology; Glutamic Acid; Ions; Kainic Acid; Kinetics; Ligands; Models, Biological; Models, Chemical; Models, Molecular; Mutagenesis; Mutation; Oocytes; Patch-Clamp Techniques; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, AMPA; RNA, Complementary; Tryptophan; Tyrosine; Xenopus laevis | 2005 |
An on-pathway hidden intermediate and the early rate-limiting transition state of Rd-apocytochrome b562 characterized by protein engineering.
Topics: Alanine; Cytochromes b; Glycine; Models, Molecular; Mutation; Protein Engineering; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Tryptophan | 2005 |
A crystallographic study of Cys69Ala flavodoxin II from Azotobacter vinelandii: structural determinants of redox potential.
Topics: Alanine; Amino Acid Sequence; Azotobacter vinelandii; Binding Sites; Crystallography, X-Ray; Cysteine; Flavin Mononucleotide; Flavodoxin; Glycine; Hydrogen Bonding; Leucine; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Folding; Sequence Homology, Amino Acid; Structural Homology, Protein; Tryptophan | 2005 |
Kinetics of the interaction of sulfate and hydrogen phosphate radicals with small peptides of glycine, alanine, tyrosine and tryptophan.
Topics: Alanine; Glycine; Kinetics; Peptides; Phosphates; Photochemistry; Sulfates; Tryptophan; Tyrosine | 2005 |
Tryptophan at position 104 is involved in transforming light signal into changes of beta-sheet structure for the signaling state in the BLUF domain of AppA.
Topics: Alanine; Apoproteins; Bacterial Proteins; Escherichia coli; Flavoproteins; Light; Light Signal Transduction; Mutation; Protein Structure, Secondary; Protein Structure, Tertiary; Spectroscopy, Fourier Transform Infrared; Time Factors; Tryptophan; Ultraviolet Rays | 2005 |
Critical structure-function determinants within the N-terminal region of pulmonary surfactant protein SP-B.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Adsorption; Alanine; Amino Acid Sequence; Amino Acids; Circular Dichroism; Humans; Kinetics; Lipid Bilayers; Molecular Sequence Data; Peptides; Phosphatidylglycerols; Phospholipids; Pressure; Proline; Protein Structure, Secondary; Protein Structure, Tertiary; Pulmonary Surfactant-Associated Protein B; Structure-Activity Relationship; Time Factors; Tryptophan; Ultraviolet Rays | 2006 |
Purification and characterization of spiralin, the main protein of the Spiroplasma citri membrane.
Topics: Alanine; Bacterial Outer Membrane Proteins; Biochemistry; Buffers; Cell Membrane; Detergents; Electrophoresis; Electrophoresis, Agar Gel; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glycine; Histidine; Immunoelectrophoresis; Intracellular Membranes; Leucine; Methionine; Molecular Weight; Phenylalanine; Sepharose; Spiroplasma citri; Subcellular Fractions; Threonine; Tryptophan; Tyrosine; Valine | 1977 |
Quantitative measurement of serotonin synthesis and sequestration in individual live neuronal cells.
Topics: Alanine; Animals; Cell Line, Transformed; Diagnostic Imaging; Dose-Response Relationship, Drug; Exocytosis; Imaging, Three-Dimensional; Immunohistochemistry; Microscopy; Neurons; Photons; Rats; Serotonin; Transport Vesicles; Tryptophan | 2005 |
Role of the transmembrane domain of FXYD7 in structural and functional interactions with Na,K-ATPase.
Topics: Adenosine Triphosphatases; Alanine; Amino Acids; Animals; Cell Membrane; Cloning, Molecular; Dimerization; Electrophysiology; Glycine; Immunoprecipitation; Isoleucine; Membrane Glycoproteins; Membrane Potentials; Mice; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Oocytes; Patch-Clamp Techniques; Polymerase Chain Reaction; Potassium; Protein Binding; Protein Structure, Tertiary; Rats; RNA, Complementary; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship; Tryptophan; Valine; Xenopus | 2005 |
Deficiency of disulfide bonds facilitating fibrillogenesis of endostatin.
Topics: Alanine; Alzheimer Disease; Animals; Benzothiazoles; Cell Survival; Circular Dichroism; Disulfides; Endostatins; Escherichia coli; Fibril-Associated Collagens; Fluorescent Dyes; Glutathione; Hydrogen-Ion Concentration; Light; Microscopy, Atomic Force; Neovascularization, Pathologic; PC12 Cells; Protein Conformation; Protein Structure, Tertiary; Rats; Scattering, Radiation; Spectroscopy, Fourier Transform Infrared; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Tryptophan; Ultraviolet Rays | 2006 |
Conversion of a porin-like peptide channel into a gramicidin-like channel by glycine to D-alanine substitutions.
Topics: Alanine; Amino Acids; Cations; Cell Membrane; Circular Dichroism; Electrolytes; Glycine; Gramicidin; Ion Channels; Lipid Bilayers; Models, Molecular; Peptides; Porins; Protein Conformation; Protein Folding; Protein Structure, Secondary; Spectrophotometry, Infrared; Time Factors; Tryptophan | 2006 |
Synergistic effects on escape of a ligand from the closed tryptophan synthase bienzyme complex.
Topics: Alanine; Allosteric Regulation; Bacteria; Benzimidazoles; Catalytic Domain; Glycerophosphates; Indoles; Ligands; Models, Chemical; Models, Molecular; Protein Binding; Spectrophotometry; Tryptophan; Tryptophan Synthase | 2005 |
Interactions involved in the realignment of membrane-associated helices. An investigation using oriented solid-state NMR and attenuated total reflection Fourier transform infrared spectroscopies.
Topics: Alanine; Amino Acid Sequence; Cell Membrane; Detergents; DNA; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Lipid Bilayers; Magnetic Resonance Spectroscopy; Micelles; Models, Chemical; Models, Statistical; Molecular Sequence Data; Peptides; Protein Structure, Secondary; Protons; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Transfection; Tryptophan; Tyrosine | 2006 |
A non-cleavable UmuD variant that acts as a UmuD' mimic.
Topics: Alanine; DNA Polymerase III; DNA-Directed DNA Polymerase; Escherichia coli; Escherichia coli Proteins; Mutagenesis, Site-Directed; Phenotype; Protein Binding; Tryptophan; Two-Hybrid System Techniques; Ultraviolet Rays | 2006 |
Fluorescence energy transfer studies of human deoxycytidine kinase: role of cysteine 185 in the conformational changes that occur upon substrate binding.
Topics: Alanine; Binding Sites; Cysteine; Deoxycytidine Kinase; Energy Transfer; Enzyme Activation; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Kinetics; Maleimides; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Nucleosides; Phosphates; Protein Binding; Protein Conformation; Substrate Specificity; Tryptophan | 2006 |
Structure of a complex of Thermoactinomyces vulgaris R-47 alpha-amylase 2 with maltohexaose demonstrates the important role of aromatic residues at the reducing end of the substrate binding cleft.
Topics: Alanine; alpha-Amylases; Amino Acid Substitution; Amino Acids, Aromatic; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Hydrogen Bonding; Hydrolysis; Kinetics; Micromonosporaceae; Models, Molecular; Oligosaccharides; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Substrate Specificity; Tryptophan; Tyrosine; Water | 2006 |
Roles of the human Rad51 L1 and L2 loops in DNA binding.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; DNA Repair; DNA-Binding Proteins; Humans; Molecular Sequence Data; Protein Binding; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Rad51 Recombinase; Recombination, Genetic; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 2006 |
Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin.
Topics: Alanine; Calorimetry; Complement C3; Enzyme-Linked Immunosorbent Assay; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Naphthalenes; Peptides, Cyclic; Protein Binding; Static Electricity; Structure-Activity Relationship; Tryptophan | 2006 |
Two separate, conserved acidic amino acid domains within the Toxoplasma gondii MIC2 cytoplasmic tail are required for parasite survival.
Topics: Alanine; Amino Acid Sequence; Animals; Cytoplasm; DNA Mutational Analysis; Fructose-Bisphosphate Aldolase; Membrane Proteins; Models, Genetic; Molecular Sequence Data; Point Mutation; Protein Binding; Protein Structure, Tertiary; Protozoan Proteins; Sequence Homology, Amino Acid; Toxoplasma; Tryptophan | 2006 |
Insight into heme protein redox potential control and functional aspects of six-coordinate ligand-sensing heme proteins from studies of synthetic heme peptides.
Topics: Alanine; Cytochromes b5; Electrochemistry; Hemeproteins; Histidine; Hydrogen-Ion Concentration; Iron; Ligands; Mesoporphyrins; Microsomes; Mitochondria; Oxidation-Reduction; Peptides; Protein Binding; Protein Conformation; Protein Isoforms; Solvents; Tryptophan | 2006 |
The putative transmembrane segment 7 of human organic anion transporter hOAT1 dictates transporter substrate binding and stability.
Topics: Alanine; Amino Acid Substitution; Animals; Biological Transport; Biotinylation; Blotting, Western; Cell Membrane; Chlorocebus aethiops; COS Cells; Humans; Mutagenesis, Site-Directed; Organic Anion Transport Protein 1; p-Aminohippuric Acid; Protein Binding; Substrate Specificity; Transfection; Tryptophan; Tyrosine | 2007 |
Structure-activity relationship studies on quorum sensing ComX(RO-E-2) pheromone.
Topics: Alanine; Amino Acid Substitution; Bacillus; Bacterial Proteins; Chromatography, High Pressure Liquid; Indicators and Reagents; Lac Operon; Mass Spectrometry; Quorum Sensing; Structure-Activity Relationship; Tryptophan | 2007 |
Site-directed mutagenesis of two aromatic residues lining the active site pocket of the yeast Ltp1.
Topics: Alanine; Amino Acid Substitution; Amino Acids, Aromatic; Binding Sites; Catalysis; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Protein Tyrosine Phosphatases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Tryptophan; Tyrosine | 2007 |
A role for the S0 transmembrane segment in voltage-dependent gating of BK channels.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Calcium; Cells, Cultured; Humans; Ion Channel Gating; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Mice; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutation; Recombinant Proteins; Sequence Alignment; Tryptophan | 2007 |
Local inhibitory reflexes excited by mucosal application of nutrient amino acids in guinea pig jejunum.
Topics: Action Potentials; Adenosine Triphosphate; Alanine; Amino Acids; Animals; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Intestinal Mucosa; Jejunum; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Neural Inhibition; Phenylalanine; Reaction Time; Receptor, Cholecystokinin B; Receptors, Purinergic P2; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Reflex; Serotonin; Sincalide; Tryptophan | 2007 |
Unveiling hidden catalytic contributions of the conserved His/Trp-III in tyrosine recombinases: assembly of a novel active site in Flp recombinase harboring alanine at this position.
Topics: Alanine; Amino Acid Sequence; Catalytic Domain; Conserved Sequence; DNA Nucleotidyltransferases; Histidine; Hydrogen Peroxide; Models, Genetic; Models, Molecular; Mutation; Recombinases; Substrate Specificity; Tryptophan; Tyramine; Tyrosine | 2007 |
Domain organization and polarity of tail needle GP26 in the portal vertex structure of bacteriophage P22.
Topics: Alanine; Bacteriophage P22; Guanidine; Hydrophobic and Hydrophilic Interactions; Mutation; Open Reading Frames; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Transition Temperature; Tryptophan; Viral Proteins | 2007 |
Complexation of Al(III) by aromatic amino acids in the gas phase.
Topics: Alanine; Aluminum; Amino Acids; Cations; Metals; Models, Chemical; Models, Molecular; Molecular Conformation; Nitrogen; Oxygen; Phenylalanine; Software; Solvents; Tryptophan; Tyrosine | 2007 |
Generation of quinoneimine intermediates in the bioactivation of 3-(N-phenylamino)alanine (PAA) by human liver microsomes: a potential link between eosinophilia-myalgia syndrome and toxic oil syndrome.
Topics: Alanine; Biotransformation; Chromatography, High Pressure Liquid; Disease Outbreaks; Eosinophilia-Myalgia Syndrome; Fatty Acids, Monounsaturated; Food Contamination; Foodborne Diseases; Humans; Microsomes, Liver; Plant Oils; Quinones; Rapeseed Oil; Spain; Spectrometry, Mass, Electrospray Ionization; Tryptophan | 2007 |
Oxindolealanine in age-related human cataracts.
Topics: Aged; Aged, 80 and over; Alanine; alpha-Crystallins; Animals; Biomarkers; Cataract; Cattle; Chromatography, High Pressure Liquid; Humans; Indoles; Lens Cortex, Crystalline; Lens Nucleus, Crystalline; Lens, Crystalline; Oxidation-Reduction; Oxindoles; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tryptophan | 2007 |
The interaction of arginine- and tryptophan-rich cyclic hexapeptides with Escherichia coli membranes.
Topics: Alanine; Amino Acid Sequence; Antimicrobial Cationic Peptides; Escherichia coli; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Oligopeptides; Peptides, Cyclic; Structure-Activity Relationship; Time Factors; Tryptophan | 2008 |
Molecular dynamics simulation of human LOX-1 provides an explanation for the lack of OxLDL binding to the Trp150Ala mutant.
Topics: Alanine; Computer Simulation; Crystallography, X-Ray; Humans; Hydrogen Bonding; Lipoproteins, LDL; Models, Molecular; Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Scavenger Receptors, Class E; Tryptophan | 2007 |
Molecular mechanism of target recognition by subtilin, a class I lanthionine antibiotic.
Topics: Alanine; Anti-Bacterial Agents; Bacteriocins; Cell Membrane; Coated Vesicles; Diphosphates; Fluoresceins; Lactococcus lactis; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Succinic Acid; Sulfides; Tryptophan; Uridine Diphosphate N-Acetylmuramic Acid | 2008 |
Expression and purification of a Plasmodium vivax antigen - PvTARAg55 tryptophan- and alanine-rich antigen and its immunological responses in human subjects.
Topics: Alanine; Amino Acid Sequence; Animals; Antibodies, Protozoan; Antigens, Protozoan; Cytokines; Exons; Humans; Lymphocyte Activation; Malaria Vaccines; Molecular Sequence Data; Plasmodium vivax; Repetitive Sequences, Amino Acid; Tryptophan; Vaccines, Synthetic | 2007 |
About the breakdown of tryptophan to alanine and anthranilic acid in the animal organism.
Topics: Alanine; ortho-Aminobenzoates; Tryptophan | 1949 |
Analysis of tryptophan residues in the staphylococcal multidrug transporter QacA reveals long-distance functional associations of residues on opposite sides of the membrane.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Benzalkonium Compounds; Biological Transport; Blotting, Western; Cell Membrane; Chlorhexidine; Dequalinium; Drug Resistance, Microbial; Electrophoresis, Polyacrylamide Gel; Ethidium; Fluoresceins; Indoles; Membrane Transport Proteins; Microbial Sensitivity Tests; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Pentamidine; Phenylalanine; Protein Structure, Secondary; Pyronine; Rhodamines; Staphylococcus; Tryptophan | 2008 |
Characterization of ligand-binding properties of the human BMP type II receptor extracellular domain.
Topics: Activin Receptors, Type II; Alanine; Amino Acid Sequence; Amino Acid Substitution; Bone Morphogenetic Protein Receptors, Type II; Conserved Sequence; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Tertiary; Tryptophan; Tyrosine | 2008 |
Monitoring fibril formation of the N-terminal domain of PABPN1 carrying an alanine repeat by tryptophan fluorescence and real-time NMR.
Topics: Alanine; Amino Acid Sequence; Amyloid; Fluorescence; Humans; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Poly(A)-Binding Protein II; Protein Structure, Tertiary; Recombinant Proteins; Repetitive Sequences, Amino Acid; Tryptophan | 2008 |
Structural mobility of the monomeric C-terminal domain of the HIV-1 capsid protein.
Topics: Alanine; Biochemistry; Capsid Proteins; Dimerization; HIV-1; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Mutation; Peptides; Protein Conformation; Protein Structure, Tertiary; Time Factors; Tryptophan | 2008 |
Enhanced transdermal delivery of a dipeptide by dermaportation.
Topics: Administration, Cutaneous; Alanine; Cells, Cultured; Dipeptides; Drug Delivery Systems; Epidermis; Female; Humans; Models, Biological; Skin Absorption; Tryptophan | 2008 |
Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux.
Topics: Adenosine Triphosphate; Alanine; alpha-Synuclein; Analysis of Variance; Animals; Calcium; Cell Line, Tumor; Cobalt; Dose-Response Relationship, Drug; Flufenamic Acid; Gene Expression Regulation; Green Fluorescent Proteins; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Mitochondria; Mutation; Neuroblastoma; Neurons; Protein Kinases; Rats; Threonine; Transfection; Tryptophan | 2009 |
The terahertz dance of water with the proteins: the effect of protein flexibility on the dynamical hydration shell of ubiquitin.
Topics: Alanine; Crystallography, X-Ray; Phenylalanine; Protein Conformation; Protein Folding; Solubility; Solvents; Terahertz Spectroscopy; Tryptophan; Ubiquitin; Water | 2009 |
Amidation of bioactive peptides: the structure of the lyase domain of the amidating enzyme.
Topics: Alanine; Amidine-Lyases; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Binding Sites; Calcium; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Glycine; Hippurates; Histidine; Hydrophobic and Hydrophilic Interactions; Kinetics; Lyases; Methionine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Peptides; Protein Binding; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Reproducibility of Results; Substrate Specificity; Transfection; Tryptophan; Tyrosine; Zinc | 2009 |
Mmp-20 and Klk4 cleavage site preferences for amelogenin sequences.
Topics: Alanine; Amelogenesis; Amelogenin; Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dental Enamel; Dental Enamel Proteins; Electrophoresis, Polyacrylamide Gel; Histidine; Kallikreins; Matrix Metalloproteinase 20; Proline; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Swine; Tandem Mass Spectrometry; Tryptophan | 2009 |
AMINO ACID COMPOSITION OF HIGHLY PURIFIED VIRAL PARTICLES OF INFLUENZA A AND B.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Humans; Influenza, Human; Isoleucine; Leucine; Lysine; Methionine; Orthomyxoviridae; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine; Virion | 1947 |
Fluorescent analogues of the insect neuropeptide helicokinin I: synthesis, photophysical characterization and biological activity.
Topics: Alanine; Amino Acid Sequence; Animals; Fluorescent Dyes; Insect Hormones; Insect Proteins; Models, Molecular; Moths; Neuropeptides; Receptors, Peptide; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 2010 |
Residue N84 of yeast cystathionine beta-synthase is a determinant of reaction specificity.
Topics: Alanine; Aspartic Acid; Catalysis; Cystathionine; Cystathionine beta-Synthase; Histidine; Homocysteine; Kinetics; Mutation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Substrate Specificity; Time Factors; Tryptophan | 2010 |
On the synthesis of two compounds that are isosteric with tryptophan: beta- [coumaronyl (3)] - alanine and beta- [naphtyl- (1)] - alanine.
Topics: Alanine; Tryptophan | 1947 |
Synthesis and biological characterization of argyrin F.
Topics: Alanine; Antineoplastic Agents; Cell Line; Cyclin-Dependent Kinase Inhibitor p27; Humans; Kinetics; Peptide Hydrolases; Peptides, Cyclic; Protease Inhibitors; Proteasome Inhibitors; RNA Interference; RNA, Small Interfering; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Tryptophan | 2010 |
Fatty acid modulation and polyamine block of GluK2 kainate receptors analyzed by scanning mutagenesis.
Topics: Alanine; Amino Acid Sequence; Arginine; Cell Line; Chlorides; Docosahexaenoic Acids; GluK2 Kainate Receptor; Humans; Ion Channel Gating; Membrane Potentials; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Patch-Clamp Techniques; Permeability; Protein Conformation; Receptors, Kainic Acid; Spermine; Structure-Activity Relationship; Transfection; Tryptophan | 2010 |
Acquisition of Raman spectra of amino acids using portable instruments: outdoor measurements and comparison.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; beta-Alanine; Glutamic Acid; Glutamine; Glycine; Methionine; Proline; Research Design; Robotics; Serine; Spectrum Analysis, Raman; Transportation; Tryptophan; Tyrosine; Workplace | 2010 |
Synthesis of peptides containing 5-hydroxytryptophan, oxindolylalanine, N-formylkynurenine and kynurenine.
Topics: 5-Hydroxytryptophan; Alanine; Amino Acid Sequence; Humans; Kynurenine; Molecular Sequence Data; Molecular Structure; Oxidation-Reduction; Oxindoles; Peptides; Tryptophan | 2011 |
SSTR1- and SSTR3-selective somatostatin analogues.
Topics: Alanine; Animals; Biological Assay; Cells, Cultured; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Quinolines; Receptors, Somatostatin; Somatostatin; Stereoisomerism; Substrate Specificity; Tryptophan | 2011 |
The role of Ala231 and Trp227 in the substrate specificities of fungal 17β-hydroxysteroid dehydrogenase and trihydroxynaphthalene reductase: Steroids versus smaller substrates.
Topics: 17-Hydroxysteroid Dehydrogenases; Alanine; Amino Acid Sequence; Ascomycota; Benzopyrans; Catalytic Domain; Estrenes; Fungal Proteins; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Phenanthrenes; Steroids; Substrate Specificity; Tryptophan | 2012 |
Insights on the mechanism of proton transfer reactions in amino acids.
Topics: Alanine; Amino Acids; Models, Chemical; Models, Molecular; Molecular Dynamics Simulation; Phenylalanine; Protons; Thermodynamics; Tryptophan; Water | 2011 |
Positions of polar amino acids alter interactions between transmembrane segments and detergents.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Detergents; Hydrophobic and Hydrophilic Interactions; Membrane Proteins; Molecular Sequence Data; Peptide Fragments; Protein Folding; Protein Structure, Secondary; Sodium Dodecyl Sulfate; Tryptophan | 2011 |
Response of GWALP transmembrane peptides to changes in the tryptophan anchor positions.
Topics: Acetylation; Alanine; Amino Acid Sequence; Deuterium Exchange Measurement; Glycine; Lipid Bilayers; Membrane Proteins; Membranes, Artificial; Molecular Sequence Data; Peptide Fragments; Protein Engineering; Tryptophan | 2011 |
Altered tryptophan and alanine transport in fibroblasts from boys with attention-deficit/hyperactivity disorder (ADHD): an in vitro study.
Topics: Alanine; Attention Deficit Disorder with Hyperactivity; Blood-Brain Barrier; Cells, Cultured; Child; Fibroblasts; Humans; Male; Protein Transport; Tryptophan | 2011 |
Structure of a monomeric mutant of the HIV-1 capsid protein.
Topics: Alanine; Capsid Proteins; Crystallography, X-Ray; HIV-1; Humans; Methionine; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Multimerization; Protein Structure, Tertiary; Solutions; Structure-Activity Relationship; Tryptophan; Virus Assembly | 2011 |
Mass spectrometric characterization of peptides containing different oxidized tryptophan residues.
Topics: 5-Hydroxytryptophan; Alanine; Amino Acid Sequence; Animals; Kynurenine; Molecular Sequence Data; Muscle Proteins; Oxidation-Reduction; Oxindoles; Peptides; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan | 2011 |
Pharmacological activity of a Bv8 analogue modified in position 24.
Topics: Alanine; Amino Acid Substitution; Amphibian Proteins; Analgesics; Animals; Chemotaxis; CHO Cells; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Hyperalgesia; Ligands; Macrophages; Male; Mice; Neuropeptides; Pain, Postoperative; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Peptide; Structure-Activity Relationship; Transfection; Tryptophan | 2012 |
Active site substitution A82W improves the regioselectivity of steroid hydroxylation by cytochrome P450 BM3 mutants as rationalized by spin relaxation nuclear magnetic resonance studies.
Topics: Alanine; Amino Acid Substitution; Bacillus megaterium; Bacterial Proteins; Biotransformation; Catalytic Domain; Cytochrome P-450 Enzyme System; Hydroxylation; Mutagenesis, Site-Directed; NADPH-Ferrihemoprotein Reductase; Norethindrone; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Testosterone; Tryptophan | 2012 |
Immobilization of chitosan in sol-gel phases for chiral open-tubular capillary electrochromatography.
Topics: Alanine; Capillary Electrochromatography; Catechin; Chitosan; Glycine; Hydrophobic and Hydrophilic Interactions; Phase Transition; Sensitivity and Specificity; Silanes; Stereoisomerism; Tryptophan | 2012 |
Structural implication for the impaired binding of W150A mutant LOX-1 to oxidized low density lipoprotein, OxLDL.
Topics: Alanine; Binding Sites; Crystallography, X-Ray; Endothelial Cells; Escherichia coli; Humans; Lipoproteins, LDL; Molecular Docking Simulation; Mutation; Oxidation-Reduction; Protein Binding; Protein Folding; Protein Multimerization; Protein Stability; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Fusion Proteins; Scavenger Receptors, Class E; Tryptophan | 2012 |
Reduction of chronic graft injury with a new HTK-based preservation solution in a murine heart transplantation model.
Topics: Alanine; Animals; Cold Ischemia; Endomyocardial Fibrosis; Glycine; Heart; Heart Transplantation; Histidine; Ketoglutaric Acids; Male; Mice; Mice, Inbred C57BL; Models, Animal; Organ Preservation Solutions; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transplantation, Heterotopic; Transplantation, Isogeneic; Tryptophan | 2012 |
Precursors and nitrogen origins of trichloronitromethane and dichloroacetonitrile during chlorination/chloramination.
Topics: Acetonitriles; Alanine; Asparagine; Chloramines; Gas Chromatography-Mass Spectrometry; Halogenation; Hydrocarbons, Chlorinated; Hydrogen-Ion Concentration; Nitrogen; Tryptophan; Tyrosine | 2012 |
The role of the second and third extracellular loops of the adenosine A1 receptor in activation and allosteric modulation.
Topics: Alanine; Allosteric Regulation; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Glutamic Acid; Humans; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Receptor, Adenosine A1; Saccharomyces cerevisiae; Sequence Alignment; Thiophenes; Tryptophan | 2012 |
Role of tryptophan residues in a class V chitinase from Nicotiana tabacum.
Topics: Acetylglucosamine; Alanine; Binding Sites; Chitinases; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Enzyme Stability; Escherichia coli; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Nicotiana; Phenylalanine; Plant Proteins; Plasmids; Recombinant Proteins; Tryptophan | 2012 |
Tryptophan stabilizes His-heme loops in the denatured state only when it is near a loop end.
Topics: Alanine; Guanidine; Hemeproteins; Histidine; Protein Denaturation; Protein Stability; Protein Structure, Secondary; Tryptophan | 2012 |
The roles of tryptophans in primer synthesis by the DNA primase of bacteriophage T7.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Substitution; Bacteriophage T7; Binding Sites; Biocatalysis; DNA Primase; DNA Primers; DNA, Single-Stranded; Genetic Complementation Test; Kinetics; Mutation; Oligoribonucleotides; Protein Binding; Surface Plasmon Resonance; Templates, Genetic; Tryptophan; Tyrosine; Viral Proteins; Virus Replication; Zinc | 2012 |
Prenylation at the indole ring leads to a significant increase of cytotoxicity of tryptophan-containing cyclic dipeptides.
Topics: Alanine; Biocatalysis; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Dimethylallyltranstransferase; Dipeptides; Fungal Proteins; Hemiterpenes; Humans; Indoles; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Organophosphorus Compounds; Peptides, Cyclic; Prenylation; Proline; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity; Tryptophan | 2012 |
Screening for POLG W748S and A467T mutations in ataxia patients from Spain.
Topics: Adult; Age of Onset; Aged; Alanine; Ataxia; DNA Polymerase gamma; DNA-Directed DNA Polymerase; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Male; Middle Aged; Mutation; Polymorphism, Single Nucleotide; Serine; Spain; Threonine; Tryptophan; Young Adult | 2012 |
Native state conformational heterogeneity of HP35 revealed by time-resolved FRET.
Topics: Alanine; Fluorescence Resonance Energy Transfer; Kinetics; Microfilament Proteins; Nitriles; Protein Folding; Protein Structure, Tertiary; Tryptophan | 2012 |
Serum stability of selected decapeptide agonists of KISS1R using pseudopeptides.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Glycine; Humans; Kisspeptins; Mice; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Serum; Tryptophan | 2012 |
In vitro degradation of lysine by ruminal fluid-based fermentations and by Fusobacterium necrophorum.
Topics: Acetic Acid; Alanine; Animals; Cattle; Fermentation; Fusobacterium necrophorum; Gastric Juice; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Lysine; Methionine; Propionates; Rumen; Tryptophan | 2013 |
The role of amino acids in spina bifida.
Topics: Adult; Alanine; Amino Acids; Amniocentesis; Amniotic Fluid; Cystathionine; Cysteine; Female; Gestational Age; Humans; Phenylalanine; Pregnancy; Pregnancy Trimester, Second; Spinal Dysraphism; Tryptophan; Tyrosine; Ultrasonography, Prenatal | 2012 |
Juxtamembrane tryptophans of synaptobrevin 2 control the process of membrane fusion.
Topics: Alanine; Amino Acid Substitution; Animals; Cells, Cultured; Chromaffin Cells; Embryo, Mammalian; Exocytosis; Hydrophobic and Hydrophilic Interactions; Membrane Fusion; Mice; Mice, Knockout; Mutagenesis, Site-Directed; Mutant Proteins; Patch-Clamp Techniques; Protein Stability; Protein Structure, Tertiary; Recombinant Proteins; Tryptophan; Vesicle-Associated Membrane Protein 2; Vesicle-Associated Membrane Protein 3 | 2013 |
Structural basis of the interaction of MbtH-like proteins, putative regulators of nonribosomal peptide biosynthesis, with adenylating enzymes.
Topics: Adenosine Monophosphate; Alanine; Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Aspartic Acid; Bacterial Proteins; Crystallography, X-Ray; Escherichia coli; Models, Molecular; Molecular Sequence Data; Multigene Family; Mutation; Peptide Biosynthesis, Nucleic Acid-Independent; Peptide Synthases; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Tryptophan | 2013 |
Aromatic interactions with naphthylalanine in a β-hairpin peptide.
Topics: Alanine; Amino Acids, Aromatic; Dermatan Sulfate; Naphthalenes; Peptides; Phenylalanine; Tryptophan | 2013 |
Controlling enzyme inhibition using an expanded set of genetically encoded amino acids.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Computer Simulation; Escherichia coli; Folic Acid; Folic Acid Antagonists; Methotrexate; Mice; Models, Molecular; Molecular Sequence Data; Naphthalenes; Phenylalanine; Protein Binding; Protein Engineering; Recombinant Proteins; Sequence Alignment; Tetrahydrofolate Dehydrogenase; Tryptophan | 2013 |
Defining a key receptor-CheA kinase contact and elucidating its function in the membrane-bound bacterial chemosensory array: a disulfide mapping and TAM-IDS Study.
Topics: Adaptor Proteins, Signal Transducing; Alanine; Bacterial Proteins; Chemotaxis; Disulfides; Escherichia coli; Escherichia coli Proteins; Histidine Kinase; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Models, Chemical; Molecular Docking Simulation; Protein Kinases; Protein Structure, Tertiary; Signal Transduction; Tryptophan | 2013 |
Binding of RNA by APOBEC3G controls deamination-independent restriction of retroviruses.
Topics: Alanine; Amino Acid Substitution; Animals; APOBEC Deaminases; Catalytic Domain; Cytidine Deaminase; Cytosine Deaminase; Deamination; Enzyme Activation; HEK293 Cells; HIV-1; Humans; Mice; Moloney murine leukemia virus; NIH 3T3 Cells; Protein Multimerization; Reverse Transcription; RNA, Viral; Tryptophan; Virus Assembly; Virus Integration; Virus Release | 2013 |
The perturbation of tryptophan fluorescence by phenylalanine to alanine mutations identifies the hydrophobic core in a subset of bacterial Ig-like domains.
Topics: Alanine; Arthrobacter; Fluorescence; Hydrophobic and Hydrophilic Interactions; Immunoglobulins; Phenylalanine; Tryptophan | 2013 |
Structural characterization of new microcystins containing tryptophan and oxidized tryptophan residues.
Topics: Alanine; Chromatography, Liquid; Kynurenine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microcystins; Microcystis; Oxidation-Reduction; Oxindoles; Tandem Mass Spectrometry; Tryptophan | 2013 |
Dissecting the contributions of β-hairpin tyrosine pairs to the folding and stability of long-lived human γD-crystallins.
Topics: Alanine; Cataract; Cations; gamma-Crystallins; Humans; Hydrophobic and Hydrophilic Interactions; Kynurenine; Models, Molecular; Molecular Dynamics Simulation; Mutation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Tryptophan; Tyrosine; Ultraviolet Rays | 2014 |
Heavy atom induced phosphorescence study on the influence of internal structural factors on the photophysics of tryptophan in aqueous solutions.
Topics: Alanine; Fluorescence; Hydrogen-Ion Concentration; Oligopeptides; Tryptophan | 2014 |
Easy preparation of dehydroalanine building blocks equipped with oxazolidin-2-one chiral auxiliaries, and applications to the stereoselective synthesis of substituted tryptophans.
Topics: Alanine; Kinetics; Models, Chemical; Molecular Structure; Oligopeptides; Oxazolidinones; Receptors, Opioid, mu; Stereoisomerism; Tryptophan | 2014 |
Kinetics of cellobiohydrolase (Cel7A) variants with lowered substrate affinity.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Binding, Competitive; Biocatalysis; Catalytic Domain; Cellobiose; Cellulose; Cellulose 1,4-beta-Cellobiosidase; Fungal Proteins; Kinetics; Models, Molecular; Mutation; Protein Binding; Substrate Specificity; Thermodynamics; Trichoderma; Tryptophan | 2014 |
Biosynthetic incorporation of the azulene moiety in proteins with high efficiency.
Topics: Alanine; Azulenes; Bacterial Proteins; Lactococcus lactis; Protein Biosynthesis; Tryptophan | 2015 |
Tryptophan-dependent membrane interaction and heteromerization with the internal fusion peptide by the membrane proximal external region of SARS-CoV spike protein.
Topics: Alanine; Amino Acid Substitution; Animals; Cell Membrane; Chlorocebus aethiops; Peptide Fragments; Phenylalanine; Protein Binding; Protein Interaction Domains and Motifs; Protein Multimerization; Severe acute respiratory syndrome-related coronavirus; Spike Glycoprotein, Coronavirus; Tryptophan; Vero Cells; Viral Fusion Proteins | 2015 |
Radical-induced, proton-transfer-driven fragmentations in [b(5)-H]˙(+) ions derived from pentaalanyl tryptophan.
Topics: Alanine; Free Radicals; Oxazolone; Peptides; Protons; Quantum Theory; Thermodynamics; Tryptophan | 2015 |
The Interaction Between β-3 Adrenergic Receptor and Peroxisome Proliferator-Activated Receptor Gamma Gene Polymorphism to Periodontal Disease in Community-Dwelling Elderly Japanese.
Topics: Aged; Alanine; Arginine; Body Mass Index; C-Reactive Protein; Epistasis, Genetic; Female; Gene-Environment Interaction; Genotype; Glycated Hemoglobin; Heterozygote; Humans; Middle Aged; Obesity; Periodontal Attachment Loss; Periodontal Diseases; Periodontal Index; Periodontal Pocket; Polymorphism, Genetic; Postmenopause; PPAR gamma; Proline; Receptors, Adrenergic, beta-3; Tooth Loss; Tryptophan | 2015 |
Probing the role of Proline in the antimicrobial activity and lipopolysaccharide binding of indolicidin.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Binding Sites; Cattle; Escherichia coli; Klebsiella pneumoniae; Lipopolysaccharides; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Neutrophils; Proline; Protein Binding; Protein Conformation; Pseudomonas aeruginosa; Salmonella typhi; Structure-Activity Relationship; Tryptophan | 2015 |
A conserved WW domain-like motif regulates invariant chain-dependent cell-surface transport of the NKG2D ligand ULBP2.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Antigens, Differentiation, B-Lymphocyte; Binding Sites; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; HEK293 Cells; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Humans; Intercellular Signaling Peptides and Proteins; Jurkat Cells; Models, Molecular; Molecular Sequence Data; NK Cell Lectin-Like Receptor Subfamily K; Protein Binding; Protein Interaction Domains and Motifs; Protein Isoforms; Protein Transport; Sequence Alignment; Signal Transduction; Tryptophan | 2015 |
A Novel Multivariate Index for Pancreatic Cancer Detection Based On the Plasma Free Amino Acid Profile.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Area Under Curve; Asparagine; Body Mass Index; Cross-Sectional Studies; Early Detection of Cancer; Fasting; Female; Histidine; Humans; Isoleucine; Japan; Male; Middle Aged; Pancreatic Neoplasms; Pancreatitis, Chronic; ROC Curve; Serine; Tryptophan; Young Adult | 2015 |
Plasma concentrations and intakes of amino acids in male meat-eaters, fish-eaters, vegetarians and vegans: a cross-sectional analysis in the EPIC-Oxford cohort.
Topics: Adult; Alanine; Amino Acids; Animals; Cross-Sectional Studies; Diet, Vegan; Diet, Vegetarian; Energy Intake; Fishes; Glycine; Humans; Lysine; Male; Meat; Methionine; Middle Aged; Seafood; Surveys and Questionnaires; Tryptophan; Tyrosine | 2016 |
Dehydrodipeptide Hydrogelators Containing Naproxen N-Capped Tryptophan: Self-Assembly, Hydrogel Characterization, and Evaluation as Potential Drug Nanocarriers.
Topics: Alanine; Cell Line, Tumor; Circular Dichroism; Drug Carriers; Humans; Hydrogels; Hydrophobic and Hydrophilic Interactions; MCF-7 Cells; Microscopy, Electron, Transmission; Models, Theoretical; Naphthalenes; Naproxen; Phenylalanine; Rheology; Tryptophan | 2015 |
Role of Non-Active-Site Residue Trp-93 in the Function and Stability of New Delhi Metallo-β-Lactamase 1.
Topics: Alanine; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Biocatalysis; Cloning, Molecular; Enterobacter cloacae; Enzyme Stability; Escherichia coli; Gene Expression; Hydrogen Bonding; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Kinetics; Models, Molecular; Mutation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Thermodynamics; Tryptophan | 2016 |
Probing the active site tryptophan of Staphylococcus aureus thioredoxin with an analog.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Catalytic Domain; Kinetics; Models, Molecular; Molecular Probes; Protein Engineering; Staphylococcus aureus; Thiophenes; Thioredoxins; Transfer RNA Aminoacylation; Tryptophan | 2015 |
Reconstitution and spectroscopic analysis of caveolin-1 residues 62-178 reveals that proline 110 governs its structure and solvent exposure.
Topics: Alanine; Caveolin 1; Cholesterol; Circular Dichroism; Hydrophobic and Hydrophilic Interactions; Micelles; Mutation; Phosphorylcholine; Proline; Protein Structure, Secondary; Solvents; Structure-Activity Relationship; Tryptophan | 2016 |
Tryptophan 299 is a conserved residue of human pregnane X receptor critical for the functional consequence of ligand binding.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Computational Biology; Crystallography, X-Ray; Cytochrome P-450 CYP3A; Diphosphonates; Epithelial Cells; Hep G2 Cells; Humans; Hydrocarbons, Fluorinated; Ligands; Luciferases; Mutation; Pregnane X Receptor; Protein Binding; Protein Conformation; Receptors, Steroid; Sulfonamides; Transfection; Tryptophan; Two-Hybrid System Techniques | 2016 |
Enantioselective Collision-Activated Dissociation of Gas-Phase Tryptophan Induced by Chiral Recognition of Protonated L-Alanine Peptides.
Topics: Alanine; Peptides; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Tryptophan | 2017 |
Role of active site loop in coenzyme binding and flavin reduction in cytochrome P450 reductase.
Topics: Alanine; Arabidopsis; Arginine; Aspartic Acid; Bacillus megaterium; Catalysis; Catalytic Domain; Chromatography, High Pressure Liquid; Cytochromes c; Flavins; Humans; Hydrogen Bonding; Kinetics; Mutagenesis, Site-Directed; Mutation; NADP; NADPH-Ferrihemoprotein Reductase; Protein Binding; Protein Domains; Saccharomyces cerevisiae; Static Electricity; Tryptophan | 2016 |
Bedaquiline Targets the ε Subunit of Mycobacterial F-ATP Synthase.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Substitution; Antitubercular Agents; Diarylquinolines; Enzyme Inhibitors; Microbial Sensitivity Tests; Molecular Targeted Therapy; Mycobacterium smegmatis; Protein Subunits; Tryptophan | 2016 |
Tuning electronic transport via hepta-alanine peptides junction by tryptophan doping.
Topics: Alanine; Electricity; Electrons; Models, Theoretical; Peptides; Temperature; Tryptophan | 2016 |
Photo-oxidation of IgG1 and Model Peptides: Detection and Analysis of Triply Oxidized His and Trp Side Chain Cleavage Products.
Topics: Alanine; Chromatography, High Pressure Liquid; Histidine; Immunoglobulin G; Light; Mass Spectrometry; Oxidation-Reduction; Peptides; Photosensitizing Agents; Tryptophan | 2017 |
Mutational analysis of protein folding inside the ribosome exit tunnel.
Topics: Alanine; Amino Acid Sequence; Biomechanical Phenomena; Circular Dichroism; DNA Mutational Analysis; Models, Molecular; Mutation; Peptides; Protein Domains; Protein Folding; Ribosomes; Tryptophan; Zinc | 2017 |
Killing of Staphylococcus aureus and Salmonella enteritidis and neutralization of lipopolysaccharide by 17-residue bovine lactoferricins: improved activity of Trp/Ala-containing molecules.
Topics: Alanine; Amino Acid Sequence; Animals; Anti-Bacterial Agents; Cattle; Endotoxemia; Female; Lactoferrin; Lipopolysaccharides; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Microbial Sensitivity Tests; Peptide Fragments; Salmonella enteritidis; Staphylococcus aureus; Tryptophan | 2017 |
Aromatic dipeptide Trp-Ala can be transported by Arabidopsis peptide transporters AtPTR1 and AtPTR5.
Topics: Alanine; Animals; Arabidopsis; Arabidopsis Proteins; Biological Transport; Cell Membrane; Dipeptides; Membrane Transport Proteins; Oocytes; Saccharomyces cerevisiae; Tryptophan; Xenopus laevis | 2017 |
Quantitative chiral analysis of amino acids in solution using enantiomer-selective photodissociation of cold gas-phase tryptophan via chiral recognition.
Topics: Alanine; Amino Acids; Serine; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Threonine; Tryptophan | 2017 |
A Residue Specific Insight into the Arkadia E3 Ubiquitin Ligase Activity and Conformational Plasticity.
Topics: Alanine; Amino Acid Substitution; Arginine; Genes, Reporter; Luciferases; Magnetic Resonance Spectroscopy; Mutant Proteins; Nuclear Proteins; Protein Conformation; Signal Transduction; Transforming Growth Factor beta; Tryptophan; Ubiquitin-Protein Ligases | 2017 |
Low levels of serum serotonin and amino acids identified in migraine patients.
Topics: Adult; Alanine; Arginine; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Dipeptides; Discriminant Analysis; Female; Humans; Male; Metabolome; Methionine; Migraine Disorders; Principal Component Analysis; Proline; RNA, Transfer, Amino Acyl; ROC Curve; Serotonin; Tryptophan | 2018 |
Enantiomeric resolution and modeling of DL-alanine-DL-tryptophan dipeptide on amylose stationary phase.
Topics: Alanine; Amylose; Chromatography, High Pressure Liquid; Dipeptides; Hydrogen; Limit of Detection; Reproducibility of Results; Stereoisomerism; Tryptophan | 2018 |
Co-addition Strategy for Enhancement of Chaetominine from Submerged Fermentation of Aspergillus fumigatus CY018.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Alanine; Aspergillus fumigatus; Bioreactors; Fermentation; Humans; Indole Alkaloids; K562 Cells; ortho-Aminobenzoates; Shikimic Acid; Transcription, Genetic; Tryptophan | 2018 |
Metabolite amyloid-like fibrils interact with model membranes.
Topics: Adenine; Alanine; Anisotropy; Diphenylhexatriene; Fluorescence; HEK293 Cells; Humans; Hydrogen Bonding; Lipid Bilayers; Macromolecular Substances; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylserines; Polyacetylene Polymer; Polymers; Polyynes; Tryptophan; Tyrosine | 2018 |
Painting argyrins blue: Negishi cross-coupling for synthesis of deep-blue tryptophan analogue β-(1-azulenyl)-l alanine and its incorporation into argyrin C.
Topics: Alanine; Azulenes; Circular Dichroism; Peptides, Cyclic; Sesquiterpenes; Spectrophotometry, Ultraviolet; Tryptophan | 2018 |
Bilirubin Interference in Plasma Amino Acid Analysis by Ion Exchange Chromatography.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Bilirubin; Cellulose; Child, Preschool; Chromatography, Ion Exchange; Cross-Sectional Studies; Cystine; Female; Glycine; Humans; Infant; Isoleucine; Leucine; Lysine; Male; Methionine; Tryptophan | 2018 |
Nine Amino Acids Are Associated With Decreased Insulin Secretion and Elevated Glucose Levels in a 7.4-Year Follow-up Study of 5,181 Finnish Men.
Topics: Aged; Alanine; Amino Acids; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Type 2; Finland; Follow-Up Studies; Glutamic Acid; Humans; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Metabolomics; Middle Aged; Phenylalanine; Risk Factors; Tryptophan; Tyrosine; Valine | 2019 |
Site-specific functionality and tryptophan mimicry of lipidation in tetraspanin CD9.
Topics: Alanine; Cell Communication; Cell Membrane; Humans; Lipids; Mutation; Protein Binding; Tetraspanin 29; Tryptophan | 2020 |
Chimeric design of pyrrolysyl-tRNA synthetase/tRNA pairs and canonical synthetase/tRNA pairs for genetic code expansion.
Topics: Alanine; Amino Acids; Chimera; Escherichia coli; Genetic Code; HEK293 Cells; Histidine; Humans; Lysine; Phenylalanine; RNA, Transfer; Synthetic Biology; Tryptophan; Tyrosine | 2020 |
The second N-terminal aromatic residue of the fungal defensin, blapersin, of Blastomyces percursus is essential for its antibacterial activity.
Topics: Alanine; Amino Acid Substitution; Anti-Bacterial Agents; Blastomyces; Defensins; Fungal Proteins; Gram-Positive Bacteria; HEK293 Cells; Hemolysis; Humans; Microbial Sensitivity Tests; Models, Molecular; Phenylalanine; Protein Conformation; Structure-Activity Relationship; Tryptophan; Tyrosine | 2020 |
Flanking aromatic residue competition influences transmembrane peptide helix dynamics.
Topics: Alanine; Amino Acid Sequence; Cell Membrane; Leucine; Lipid Bilayers; Membrane Proteins; Nuclear Magnetic Resonance, Biomolecular; Peptides; Tryptophan | 2020 |
A Tryptophan 'Gate' in the CRISPR-Cas3 Nuclease Controls ssDNA Entry into the Nuclease Site, That When Removed Results in Nuclease Hyperactivity.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Catalytic Domain; Circular Dichroism; CRISPR-Associated Proteins; CRISPR-Cas Systems; DNA; DNA Helicases; DNA, Single-Stranded; Escherichia coli; Escherichia coli Proteins; Gene Editing; Humans; Mutation, Missense; Protein Conformation; Sequence Homology, Amino Acid; Temperature; Tryptophan | 2021 |
Through bonds or contacts? Mapping protein vibrational energy transfer using non-canonical amino acids.
Topics: Alanine; Allosteric Regulation; Azulenes; Energy Transfer; Hydrogen Bonding; Molecular Dynamics Simulation; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Proteins; Quantum Theory; Solutions; Thermodynamics; Tryptophan; Vibration | 2021 |
Fluorescent Amino Acid Initiated de novo Cyclic Peptides for the Label-Free Assessment of Cell Permeability*.
Topics: Alanine; Azulenes; Cell Line, Tumor; Fluorescent Dyes; Humans; Molecular Structure; Optical Imaging; Peptides, Cyclic; Permeability; Sesquiterpenes; Tryptophan | 2021 |
Lizhong Decoction Ameliorates Ulcerative Colitis in Mice via Regulation of Plasma and Urine Metabolic Profiling.
Topics: Alanine; Amino Acids; Animals; Arachidonic Acids; Aspartic Acid; Bile Acids and Salts; Biomarkers; Colitis; Colitis, Ulcerative; Dextrans; Drugs, Chinese Herbal; Glutamates; Glycerophospholipids; Linoleic Acids; Mice; Sphingolipids; Terpenes; Tryptophan | 2022 |
Growth modulation and metabolic responses of Ganoderma boninense to salicylic acid stress.
Topics: Alanine; Arecaceae; Carbohydrates; Carbon; Chromatography, Liquid; Cluster Analysis; Coumarins; Culture Media; Ganoderma; In Vitro Techniques; Ions; Lipids; Mass Spectrometry; Melanins; Phenols; Phenylalanine; Plant Diseases; Plant Roots; Salicylic Acid; Tryptophan | 2021 |
Structural Requirements for the Binding of a Peptide to Prohibitins on the Cell Surface of Monocytes/Macrophages.
Topics: Alanine; Amino Acid Sequence; Humans; Leucine; Macrophages; Membrane Proteins; Monocytes; Peptide Library; Peptides; Prohibitins; Proteomics; Tryptophan | 2022 |
Efficient production of a cyclic dipeptide (cyclo-TA) using heterologous expression system of filamentous fungus Aspergillus oryzae.
Topics: Alanine; Aspergillus oryzae; Dipeptides; Tryptophan | 2022 |
Metabolomic profiles to explore biomarkers of severe sarcopenia in older men: A pilot study.
Topics: Aged; Aged, 80 and over; Alanine; Biomarkers; Cohort Studies; Cross-Sectional Studies; Humans; Male; Pilot Projects; Proline; Sarcopenia; Tryptophan | 2022 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
The combination of microbiome and metabolome to analyze the cross-cooperation mechanism of
Topics: Alanine; Animals; Echinacea; Fatty Acids, Volatile; Gastrointestinal Microbiome; Glycine; Glycosphingolipids; Humans; Leucine; Metabolome; Mice; Microbiota; Ornithine; Phenylalanine; Polysaccharides; Porphyrins; Serine; Threonine; Tryptophan; Tyrosine | 2022 |
[Mechanism of Cordyceps militaris against non-small cell lung cancer: based on serum metabolomics].
Topics: Alanine; Animals; Arginine; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cisplatin; Cordyceps; Glutamic Acid; Glutamine; Glyoxylates; Humans; Lung Neoplasms; Metabolomics; Mice; Mice, Nude; Nitrogen; Phenylalanine; RNA, Transfer; Tryptophan; Tyrosine | 2022 |
Effects of hydrogen peroxide and l-tryptophan on antioxidative potential, apoptosis, and mammalian target of rapamycin signaling in bovine intestinal epithelial cells.
Topics: Alanine; Animals; Antioxidants; Apoptosis; Catalase; Cattle; Cysteine; Epithelial Cells; Hydrogen Peroxide; Large Neutral Amino Acid-Transporter 1; Mammals; Oxidative Stress; Serine; Signal Transduction; Superoxide Dismutase; TOR Serine-Threonine Kinases; Tryptophan | 2022 |
The human TRPA1 intrinsic cold and heat sensitivity involves separate channel structures beyond the N-ARD domain.
Topics: Alanine; Ankyrin Repeat; Hot Temperature; Humans; Thermosensing; TRPA1 Cation Channel; Tryptophan | 2022 |
Chemical properties of inner and surficial regions of hydrogen-bonded clusters of biological molecules: ultraviolet photodissociation and water adsorption analyses in the gas phase.
Topics: Adsorption; Alanine; Hydrogen; Tandem Mass Spectrometry; Tryptophan | 2023 |
Metabolic pathway analysis of hyperuricaemia patients with hyperlipidaemia based on high-throughput mass spectrometry: a case‒control study.
Topics: Alanine; Aspartic Acid; Biomarkers; Case-Control Studies; Glycine; Humans; Hyperlipidemias; Hyperuricemia; Linoleic Acid; Mass Spectrometry; Metabolic Diseases; Metabolic Networks and Pathways; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine | 2022 |
D-Amino acid recognition of tripeptides studied by ultraviolet photodissociation spectroscopy of hydrogen-bonded clusters.
Topics: Alanine; Amino Acids; Hydrogen; Spectrum Analysis; Tryptophan | 2023 |
Uncovering the Molecular Mechanisms of Cosolvency and Predicting the Cosolvency Phenomenon by Molecular Simulations: A Case Study of Amino Acids.
Topics: Alanine; Amino Acids; Phenylalanine; Proline; Tryptophan | 2023 |
The Association between Macrosomia and Amino Acids' Levels in Maternal and Cord Sera: A Case-Control Study.
Topics: Alanine; Amino Acids; Arginine; Case-Control Studies; Chromatography, Liquid; Female; Fetal Macrosomia; Glutamic Acid; Glutamine; Histidine; Humans; Infant, Newborn; Leucine; Methionine; Tandem Mass Spectrometry; Threonine; Tryptophan; Valine | 2023 |
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |