Compounds > alanine

alanine and trienomycin a

alanine has been researched along with trienomycin a in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19906 (50.00)18.7374
1990's0 (0.00)18.2507
2000's2 (16.67)29.6817
2010's2 (16.67)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Funayama, S; Iwasaki, K; Komiyama, K; Masuda, K; Okada, K; Satoh, J; Umezawa, I1
Anraku, Y; Funayama, S; Komiyama, K; Mita, A; Omura, S; Shibata, K; Umezawa, I; Yang, ZB1
Anraku, Y; Funayama, S; Hirokawa, Y; Komiyama, K; Masuda, K; Omura, S; Umezawa, I; Yamaguchi, H1
Funayama, S; Komiyama, K; Okada, K; Umezawa, I1
Funayama, S; Iwasaki, K; Komiyama, K; Okada, K; Umezawa, I1
Ando, C; Furihata, K; Hiramoto, S; Otake, N; Sasaki, T; Seto, H; Sugita, M1
Kim, WG; Song, NK; Yoo, ID1
Futamura, Y; Hironiwa, N; Imoto, M; Kitagawa, M; Nishio, M; Suzuki, S; Tashiro, E1
Del Valle, DJ; Krische, MJ1
Li, X; Lu, C; Shen, Y; Wang, J1
Chen, H; Chen, ZF; Gao, JM; He, QR; Li, D; Liu, Y; Liu, YX; Tang, JJ; Yi, ZF1
Bian, ZY; Gao, JM; Luo, YQ; Tang, JJ; Xu, DD1

Other Studies

12 other study(ies) available for alanine and trienomycin a

ArticleYear
Studies on a novel cytocidal antibiotic, trienomycin A. Taxonomy, fermentation, isolation, and physico-chemical and biological characteristics.
    The Journal of antibiotics, 1985, Volume: 38, Issue:6

    Topics: Alanine; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Cell Line; Chemical Phenomena; Chemistry; Fermentation; HeLa Cells; Humans; Liver Neoplasms; Streptomyces

1985
Structure-activity relationship of a novel antitumor ansamycin antibiotic trienomycin A and related compounds.
    The Journal of antibiotics, 1988, Volume: 41, Issue:9

    Topics: Alanine; Animals; Antibiotics, Antineoplastic; Cyclohexanecarboxylic Acids; Female; HeLa Cells; Leukemia P388; Mice; Structure-Activity Relationship

1988
Antitumor activity of trienomycin A on murine tumors.
    The Journal of antibiotics, 1987, Volume: 40, Issue:12

    Topics: Alanine; Animals; Antibiotics, Antineoplastic; Cell Survival; DNA, Neoplasm; Female; Humans; Mice; Neoplasm Proteins; RNA, Neoplasm; Tumor Cells, Cultured

1987
Structure of trienomycin A, a novel cytocidal ansamycin antibiotic.
    The Journal of antibiotics, 1985, Volume: 38, Issue:8

    Topics: Alanine; Antibiotics, Antineoplastic; Magnetic Resonance Spectroscopy

1985
Structures of trienomycins A, B and C, novel cytocidal ansamycin antibiotics.
    The Journal of antibiotics, 1985, Volume: 38, Issue:12

    Topics: Alanine; Antibiotics, Antineoplastic; Bacteria; Chemical Phenomena; Chemistry; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry

1985
Studies on mycotrienin antibiotics, a novel class of ansamycins. V. Isolation and structure determination of novel mycotrienin congeners.
    The Journal of antibiotics, 1985, Volume: 38, Issue:8

    Topics: Alanine; Aminophenols; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Fermentation; Hydroquinones; Magnetic Resonance Spectroscopy; Streptomyces

1985
Trienomycin G, a new inhibitor of nitric oxide production in microglia cells, from Streptomyces sp. 91614.
    The Journal of antibiotics, 2002, Volume: 55, Issue:2

    Topics: Alanine; Aminophenols; Antibiotics, Antineoplastic; Bridged Bicyclo Compounds, Heterocyclic; Microglia; Molecular Structure

2002
Trierixin, a novel Inhibitor of ER stress-induced XBP1 activation from Streptomyces sp. 1. Taxonomy, fermentation, isolation and biological activities.
    The Journal of antibiotics, 2007, Volume: 60, Issue:9

    Topics: Alanine; Anti-Bacterial Agents; DNA-Binding Proteins; Endoplasmic Reticulum; Fermentation; HeLa Cells; Humans; Hydroquinones; Inhibitory Concentration 50; Lactams, Macrocyclic; Luciferases; Nuclear Proteins; Regulatory Factor X Transcription Factors; Reverse Transcriptase Polymerase Chain Reaction; Streptomyces; Stress, Physiological; Thapsigargin; Transcription Factors; X-Box Binding Protein 1

2007
Total synthesis of (+)-trienomycins A and F via C-C bond-forming hydrogenation and transfer hydrogenation.
    Journal of the American Chemical Society, 2013, Jul-31, Volume: 135, Issue:30

    Topics: Alanine; Carbon; Chemistry Techniques, Synthetic; Hydrogenation; Lactams, Macrocyclic

2013
Diversity of Polyketide Chains Achieved by Deleting the Tailoring Genes in the Biosynthesis of Ansatrienins.
    Chembiochem : a European journal of chemical biology, 2018, 02-02, Volume: 19, Issue:3

    Topics: Alanine; Aminophenols; Bridged Bicyclo Compounds, Heterocyclic; Magnetic Resonance Spectroscopy; Molecular Conformation; Polyketides; Stereoisomerism; Streptomyces

2018
The natural product trienomycin A is a STAT3 pathway inhibitor that exhibits potent in vitro and in vivo efficacy against pancreatic cancer.
    British journal of pharmacology, 2021, Volume: 178, Issue:12

    Topics: Alanine; Animals; Apoptosis; Biological Products; Cell Line, Tumor; Cell Proliferation; Mice; Molecular Docking Simulation; Pancreatic Neoplasms; Signal Transduction; STAT3 Transcription Factor

2021
Trienomycin A-simplified analogs: Synthesis and anti-neuroinflammatory activity.
    Bioorganic & medicinal chemistry letters, 2023, 01-15, Volume: 80

    Topics: Alanine; Animals; Hydrogen Peroxide; Neuroprotective Agents; PC12 Cells; Rats; Structure-Activity Relationship

2023