alanine has been researched along with thymine in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (26.53) | 18.7374 |
| 1990's | 1 (2.04) | 18.2507 |
| 2000's | 18 (36.73) | 29.6817 |
| 2010's | 14 (28.57) | 24.3611 |
| 2020's | 3 (6.12) | 2.80 |
| Authors | Studies |
|---|---|
| Chittenden, GJ; Schwartz, AW | 1 |
| Bisaillon, JG; de Repentigny, J; Mathieu, LG | 2 |
| Stroman, P | 1 |
| Kuzina, ZA; Tereshin, IM | 1 |
| Camakaris, J; Cotton, RG; Danks, DM | 1 |
| Bobikov, EV; Sazykin, IuO | 1 |
| Daniel, JC; Gulyas, BJ | 1 |
| Greco, AE; Schneider, WC | 1 |
| Congdon, PJ; Green, A; Haigh, D; Pollitt, RJ; Smith, R | 1 |
| Burke, WF; Le, HT | 1 |
| Chichenkov, ON; Kharkevich, DA; Korshunova, GA; Sumbatyan, NV; Topin, AN; Zaitsev, SV | 1 |
| Goyette, P; Rozen, R | 1 |
| Matsuno, H; Niikura, K; Okahata, Y | 1 |
| Kise, KJ; Shin, JA | 1 |
| Goseki-Sone, M; Hashimoto-Uoshima, M; Ishikawa, I; Orimo, H; Watanabe, H | 1 |
| Boyle, D; Cumming, A; Doney, A; Fischer, B; Flavell, DM; Frew, D; Montgomery, HE; Morris, A; Palmer, CN; World, M | 1 |
| Grove, A | 1 |
| FINK, K; FINK, RM; HENDERSON, RB | 1 |
| ARMSTRONG, A; HAGOPIAN, H; INGRAM, VM; SJOEQUIST, I; SJOEQUIST, J | 1 |
| Croxford, R; Kim, YI; Lucock, M; Sohn, KJ; Yates, Z | 1 |
| Atala, A; Bauer, SB; Deng, FM; Ehrlich, GD; Feather, SA; Gitlin, J; Goldberg, JD; Goodship, JA; Goodship, TH; Hermanns, M; Hu, FZ; Jiang, S; Jones, KE; Lee, A; Liang, FX; Malcolm, S; Mendelsohn, C; Ostrer, H; Preston, RA; Retik, AB; Schneck, FX; Shapiro, E; Sun, TT; Woolf, AS; Wright, V; Wu, XR; Ye, XY; Yu, J | 1 |
| Doney, AS; Fischer, B; Leese, G; Morris, AD; Palmer, CN | 1 |
| Dolman, NP; Ghosal, A; Jane, DE; Mayer, ML | 1 |
| Frerking, M; Partovi, D | 1 |
| Cheong, JJ; Choi, YD; Hwang, I; Kwon, HB; Moon, TW; Rhee, S | 1 |
| Du, M; Jayaraman, V; Rambhadran, A | 1 |
| Jane, DE; Mulle, C; Perrais, D; Pinheiro, PS | 1 |
| Atta, M; Berteau, O; Chandor-Proust, A; Douki, T; Fontecave, M; Gasparutto, D; Ollagnier-de-Choudens, S | 1 |
| Apland, JP; Aroniadou-Anderjaska, V; Braga, MF | 1 |
| Frerking, M; Wondolowski, J | 1 |
| Andreou, AP; Goadsby, PJ; Holland, PR | 1 |
| Beyrath, J; Bianco, A; Formaggio, F; Geotti-Bianchini, P; Moretto, A; Peggion, C | 1 |
| Atlason, PT; Eaves, RJ; Jane, DE; Mayo-Martin, MB; Molnár, E; Scholefield, CL | 1 |
| Brown, M; Cooper, ME; Crout, R; DeSensi, RS; Marazita, ML; McNeil, DW; Wang, X; Wendell, S; Weyant, RJ | 1 |
| Culka, A; Jehlička, J; Strnad, L | 1 |
| Chen, T; Kaang, BK; Koga, K; Sim, SE; Wu, LJ; Zhuo, M | 1 |
| Almeida-Suhett, CP; Aroniadou-Anderjaska, V; Braga, MF; Figueiredo, TH; Pidoplichko, VI; Prager, EM | 1 |
| Ahmad-Annuar, A; Aziz, ZA; Chong, YB; Eow, GB; Gopalai, AA; Kuppusamy, R; Li, HH; Lim, SK; Lim, SY; Lim, TT; Norlinah, MI; Puvanarajah, S; Tan, AH; Tan, CT; Tan, LP; Viswanathan, S; Zhao, Y | 1 |
| Ishikura, T; Maruyama, T; Matsuura, T; Ohbuchi, T; Ohkubo, J; Suzuki, H; Ueta, Y; Yoshimura, M | 1 |
| Choi, M; Gençay, K; Hu, JC; Reid, BM; Richardson, AS; Seymen, F; Simmer, JP; Tuna, E; Wang, S; Yildirim, M | 1 |
| Apland, JP; Aroniadou-Anderjaska, V; Braga, MF; Figueiredo, TH; Miller, SL; Rossetti, F | 1 |
| Chafai El Alaoui, S; Cherkaoui Jaouad, I; El Alloussi, M; Laarabi, FZ; Lyahyai, J; Sefiani, A | 1 |
| Andreou, AP; Goadsby, PJ; Holland, PR; Lasalandra, MP | 1 |
| Grosenbaugh, DK; Ross, BM; Wagley, P; Zanelli, SA | 1 |
| Kumar, J; Kumari, J; Vinnakota, R | 1 |
| Laloli, KJ; Li, KM; Lowth, A; Pickford, R; Rentsch, P; Stayte, S; Vissel, B | 1 |
| Albanese, F; Bagnati, R; Cattaneo, S; Ciammola, A; Consalez, GG; Croci, L; Davoli, E; Di Fonzo, A; Mercatelli, D; Morari, M; Novello, S; Passafaro, M; Passoni, A; Regoni, M; Sassone, J; Serratto, GM; Taverna, S; Valtorta, F; Zanetti, L | 1 |
| Smith, JC; Topham, CM | 1 |
49 other study(ies) available for alanine and thymine
| Article | Year |
|---|---|
Synthesis of uracil and thymine under simulated prebiotic conditions.
Topics: Acetates; Alanine; Chemical Phenomena; Chemistry; Hot Temperature; Minerals; Photolysis; Propionates; Thymine; Ultraviolet Rays; Uracil; Urea; Water | 1977 |
Effects of wall inhibitors on thymineless Streptococcus faecalis.
Topics: Alanine; Aminopterin; Anti-Bacterial Agents; Bacitracin; Cell Wall; Cycloserine; Enterococcus faecalis; Mutation; Penicillins; Stereoisomerism; Thymine; Vancomycin | 1974 |
Pyrimidine-sensitive drosophila wing mutants: withered (whd), tilt (tt) and dumpy (dp).
Topics: Alanine; Animals; Chromosomes; Culture Media; Drosophila melanogaster; Female; Genes, Lethal; Male; Mutation; Phenotype; Phosphotransferases; Pyrimidines; Suppression, Genetic; Thymidine; Thymine; Uracil; Uridine; Wings, Animal | 1974 |
Influence of cell wall inhibitors in thymine-requiring Staphylococcus aureus strains.
Topics: Alanine; Cell Wall; Cycloserine; DNA, Bacterial; Fluorouracil; Methicillin; Mucoproteins; Penicillin Resistance; Penicillins; Staphylococcus; Thymine | 1972 |
[The effect of a series of antibiotics on nucleic acid and protein synthesis in Salmonella pullorum].
Topics: Alanine; Bacterial Proteins; Carbon Radioisotopes; Chloramphenicol; DNA, Bacterial; Erythromycin; Lysine; RNA, Bacterial; Salmonella; Tetracycline; Thymine; Time Factors; Uracil | 1973 |
A screening test for urinary purines and pyrimidines and related compounds using auxotrophic mutants of Escherichia coli K12.
Topics: Adenine; Alanine; Aspartic Acid; Biological Assay; Carbamates; Child; Chromatography, Paper; Cytosine; Escherichia coli; Glycosides; Humans; Imidazoles; Inosine; Mutation; Orotic Acid; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Purinones; Pyrimidines; Ribose; Thymine; Uracil; Uric Acid | 1970 |
[Effect of desoxystreptamine-containing antibiotics on incorporation of labelled amino acids and precursors of nucleic acids in different fractions of Proteus vulgaris and Pseudomonas aeruginosa].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Aspartic Acid; Bacterial Proteins; Cell Wall; Depression, Chemical; DNA, Bacterial; Erythromycin Ethylsuccinate; Gentamicins; Glycine; Kanamycin; Leucine; Lysine; Methionine; Neomycin; Proteus; Pseudomonas aeruginosa; RNA, Bacterial; Thymine; Time Factors; Tyrosine; Uracil | 1969 |
Incorporation of labeled nucleic acid and protein precursors by diapausing and nondiapausing blastocysts.
Topics: Alanine; Animals; Autoradiography; Caniformia; Carbon Isotopes; Dactinomycin; DNA; Embryo Implantation; Female; In Vitro Techniques; Lactation; Mink; Morphogenesis; Ovum; Pregnancy; Protein Biosynthesis; Puromycin; Rabbits; Rats; RNA; RNA, Messenger; Thymine; Uracil; Urease; Valine; Xenarthra | 1969 |
Incorporation of pyrimidine deoxyribonucleosides into liver lipids and other components.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Aspartic Acid; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Deoxyribonucleosides; Deoxyuridine; DNA; Fatty Acids; Glutamates; Glycerides; Glycerol; Glycerylphosphorylcholine; Hydrolysis; Lipids; Liver; Male; Methionine; Mice; Microsomes, Liver; Mitochondria, Liver; Nucleosides; Phosphatidylcholines; Phosphatidylethanolamines; Protein Biosynthesis; Rats; Serine; Thymidine; Thymine; Tritium | 1971 |
Hypermethioninaemia and 3-hydroxyisobutyric aciduria in an apparently healthy baby.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Aminoisobutyric Acids; Humans; Hydroxybutyrates; Infant; Isomerism; Lactates; Lactic Acid; Methionine; Thymine; Valine | 1981 |
Construction and characterization of the host component of the Bacillus subtilis HV2 cloning system.
Topics: Alanine; Bacillus subtilis; Bacteriophages; Citric Acid Cycle; Cloning, Molecular; Mutation; Plasmids; Spores, Bacterial; Streptomycin; Thymine; Transduction, Genetic; Ultraviolet Rays | 1981 |
Opioid ligands with extraordinarily high mu-selectivity: dermorphin tetrapeptides containing thymine-modified alanine residues.
Topics: Alanine; Amino Acid Sequence; Analgesics, Opioid; Animals; Brain; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Molecular Sequence Data; Oligopeptides; Opioid Peptides; Rats; Receptors, Opioid, mu; Thymine; Vas Deferens | 1994 |
The thermolabile variant 677C-->T can further reduce activity when expressed in cis with severe mutations for human methylenetetrahydrofolate reductase.
Topics: Alanine; Alleles; Amino Acid Substitution; Catalytic Domain; Cytosine; Enzyme Activation; Gene Expression Regulation; Genetic Variation; Homocystinuria; Hot Temperature; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutagenesis, Site-Directed; Mutation, Missense; Oxidoreductases Acting on CH-NH Group Donors; Plasmids; Polymorphism, Genetic; Thymine; Valine | 2000 |
Design and characterization of asparagine- and lysine-containing alanine-based helical peptides that bind selectively to A.T base pairs of oligonucleotides immobilized on a 27 mhz quartz crystal microbalance.
Topics: Adenine; Alanine; Amino Acid Sequence; Asparagine; Base Pairing; Biosensing Techniques; Circular Dichroism; DNA-Binding Proteins; Kinetics; Lysine; Models, Chemical; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Peptides; Polydeoxyribonucleotides; Protein Binding; Protein Structure, Secondary; Thymine | 2001 |
The contribution of the methyl groups on thymine bases to binding specificity and affinity by alanine-rich mutants of the bZIP motif.
Topics: Alanine; Amino Acid Motifs; Amino Acid Substitution; Basic-Leucine Zipper Transcription Factors; Binding Sites; DNA; DNA-Binding Proteins; Fluorescence Polarization; G-Box Binding Factors; Mutation; Protein Binding; Thermodynamics; Thymine; Titrimetry; Transcription Factors; Uracil; Yeasts | 2001 |
A novel point mutation (C571T) in the tissue-non-specific alkaline phosphatase gene in a case of adult-type hypophosphatasia.
Topics: Alanine; Alkaline Phosphatase; Alleles; Alveolar Bone Loss; Chromosomes, Human, Pair 1; Cytosine; Ethanolamines; Exons; Female; Genes, Dominant; Humans; Hypophosphatasia; Introns; Middle Aged; Mutation, Missense; Pedigree; Periodontitis; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Thymine; Valine | 2001 |
Haplotype analysis of the PPARgamma Pro12Ala and C1431T variants reveals opposing associations with body weight.
Topics: Adult; Alanine; Amino Acid Substitution; Body Mass Index; Body Weight; Cytosine; Diabetes Mellitus, Type 2; Exercise; Female; Genetic Carrier Screening; Genetic Testing; Genetic Variation; Genotype; Haplotypes; Humans; Linkage Disequilibrium; Male; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Regression Analysis; Thymine; Transcription Factors | 2002 |
Surface salt bridges modulate DNA wrapping by the type II DNA-binding protein TF1.
Topics: Alanine; Anions; Aspartic Acid; Bacillus subtilis; Bacteriophages; Cations; Cross-Linking Reagents; Dimerization; DNA; DNA-Binding Proteins; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Glutaral; Ions; Kinetics; Lysine; Models, Molecular; Mutation; Pentoxyl; Plasmids; Protein Binding; Salts; Thermotoga maritima; Thymine; Viral Proteins | 2003 |
beta-amino acid formation by tissue slices incubated with pyrimidines.
Topics: Alanine; Amino Acids; Butyrates; Lipid Metabolism; Liver; Pyrimidines; Thymine; Uracil | 1953 |
CHEMICAL STUDIES ON AMINO ACID ACCEPTOR RIBONUCLEIC ACIDS. 3. THE DEGRADATION OF PURIFIED ALANINE- AND VALINE-SPECIFIC YEAST S-RNA'S BY PANCREATIC RIBONUCLEASE.
Topics: Alanine; Amino Acids; Chromatography; Cytosine; Guanine; Hypoxanthines; Nucleosides; Nucleotides; Pancreas; Research; Ribonuclease, Pancreatic; Ribonucleases; RNA; Thymine; Uracil Nucleotides; Valine; Yeasts | 1964 |
Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate.
Topics: Alanine; Animals; Antimetabolites, Antineoplastic; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Cytosine; DNA Probes; Female; Fluorouracil; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genotype; Humans; Leucovorin; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Polymorphism, Genetic; Random Allocation; Thymidylate Synthase; Thymine; Transfection; Transplantation, Heterologous; Valine | 2004 |
Lack of major involvement of human uroplakin genes in vesicoureteral reflux: implications for disease heterogeneity.
Topics: Alanine; Amino Acid Substitution; Animals; Base Sequence; Case-Control Studies; Chromosome Mapping; Cytosine; Embryo, Mammalian; Exons; Gene Expression; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Introns; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation, Missense; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Proline; Thymine; Uroplakin Ia; Uroplakin Ib; Uroplakin II; Uroplakin III; Urothelium; Vesico-Ureteral Reflux | 2004 |
Cardiovascular risk in type 2 diabetes is associated with variation at the PPARG locus: a Go-DARTS study.
Topics: Age Factors; Alanine; Alleles; Amino Acid Substitution; Cardiovascular Diseases; Cohort Studies; Cytosine; Diabetes Mellitus, Type 2; Female; Genetic Testing; Genetic Variation; Humans; Male; Middle Aged; Myocardial Infarction; Polymorphism, Genetic; PPAR gamma; Proline; Risk Factors; Sex Factors; Smoking; Thymine | 2004 |
Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Crystallography, X-Ray; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; Glutamic Acid; Hydrogen Bonding; Models, Molecular; Oocytes; Patch-Clamp Techniques; Protein Binding; Protein Conformation; Quinoxalines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Fusion Proteins; Thymine; Xenopus laevis | 2006 |
Presynaptic inhibition by kainate receptors converges mechanistically with presynaptic inhibition by adenosine and GABAB receptors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Alanine; Animals; Baclofen; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Agonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; Naphthalenes; Neuromuscular Depolarizing Agents; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Kainic Acid; Receptors, Presynaptic; Thymine | 2006 |
Complementation of an E. coli cysteine auxotrophic mutant for the structural modification study of 3'(2'),5'-bisphosphate nucleotidase.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Arabidopsis Proteins; Base Sequence; Cysteine; Cytosine; Escherichia coli; Genetic Complementation Test; Molecular Sequence Data; Mutagenesis; Mutation; Nucleotidases; Phosphoric Monoester Hydrolases; Sequence Homology, Amino Acid; Thymine; Valine | 2007 |
Luminescence resonance energy transfer investigation of conformational changes in the ligand binding domain of a kainate receptor.
Topics: Alanine; Cell Line; GluK2 Kainate Receptor; Humans; Ligands; Luminescent Measurements; Models, Molecular; Protein Structure, Tertiary; Receptors, Kainic Acid; Thymine | 2008 |
Antagonism of recombinant and native GluK3-containing kainate receptors.
Topics: Alanine; Animals; Animals, Newborn; Benzodiazepines; Biophysics; Cell Line, Transformed; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hippocampus; Humans; In Vitro Techniques; Kainic Acid; Membrane Potentials; Mice; Mice, Knockout; Mossy Fibers, Hippocampal; Neuronal Plasticity; Patch-Clamp Techniques; Protein Subunits; Pyramidal Cells; Receptors, Kainic Acid; Recombinant Proteins; Synaptic Transmission; Thymine; Transfection | 2009 |
DNA repair and free radicals, new insights into the mechanism of spore photoproduct lyase revealed by single amino acid substitution.
Topics: Alanine; Amino Acids; Bacillus subtilis; Catalysis; Catalytic Domain; Cloning, Molecular; Cysteine; DNA Repair; Free Radicals; Iron-Sulfur Proteins; Models, Chemical; Proteins; Sulfinic Acids; Thymine; Ultraviolet Rays | 2008 |
Soman induces ictogenesis in the amygdala and interictal activity in the hippocampus that are blocked by a GluR5 kainate receptor antagonist in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Amygdala; Animals; Calcium; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Seizures; Soman; Thymine | 2009 |
Subunit-dependent postsynaptic expression of kainate receptors on hippocampal interneurons in area CA1.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Baclofen; Benzothiadiazines; Biophysics; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; Galactolipids; Hippocampus; In Vitro Techniques; Interneurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Thymine | 2009 |
Activation of iGluR5 kainate receptors inhibits neurogenic dural vasodilatation in an animal model of trigeminovascular activation.
Topics: Afferent Pathways; Alanine; Animals; Calcitonin Gene-Related Peptide; Dura Mater; Electric Stimulation; Male; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Thymine; Trigeminal Nerve; Vasodilation | 2009 |
Replacement of Ala by Aib improves structuration and biological stability in thymine-based alpha-nucleopeptides.
Topics: Alanine; Amino Acid Sequence; Aminoisobutyric Acids; Animals; Cell Line, Tumor; Drug Design; Humans; Hydrolysis; Mice; Oligopeptides; Protein Conformation; Protein Stability; Thymine | 2010 |
Mapping the ligand binding sites of kainate receptors: molecular determinants of subunit-selective binding of the antagonist [3H]UBP310.
Topics: Alanine; Animals; Animals, Newborn; Binding Sites; Binding, Competitive; Crystallography, X-Ray; HEK293 Cells; Humans; Ligands; Point Mutation; Protein Subunits; Protons; Rats; Rats, Wistar; Receptors, Kainic Acid; Thymine | 2010 |
Taste genes associated with dental caries.
Topics: Adenine; Adult; Alanine; Child; Child, Preschool; Cohort Studies; Cytosine; Dental Caries; Dental Caries Susceptibility; DMF Index; Female; Gene Frequency; Genetic Variation; Genotype; Guanine; Haplotypes; Humans; Linkage Disequilibrium; Male; Polymorphism, Single Nucleotide; Proline; Receptors, G-Protein-Coupled; Risk Factors; Taste; Thymine; Transducin; Valine | 2010 |
Testing a portable Raman instrument: the detection of biomarkers in gypsum powdered matrix under gypsum crystals.
Topics: Adenine; Alanine; Biomarkers; Calcium Sulfate; Crystallization; Glycine; Powders; Spectrum Analysis, Raman; Thymine; Urea | 2012 |
Kainate receptor-mediated synaptic transmissions in the adult rodent insular cortex.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Benzodiazepines; Cerebral Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; GluK2 Kainate Receptor; Mice; Mice, Inbred C57BL; Mice, Knockout; Picrotoxin; Pyramidal Cells; Receptors, Kainic Acid; Synaptic Transmission; Thymine | 2012 |
Presynaptic facilitation of glutamate release in the basolateral amygdala: a mechanism for the anxiogenic and seizurogenic function of GluK1 receptors.
Topics: Acoustic Stimulation; Alanine; Amygdala; Animals; Bicuculline; Biophysical Phenomena; Excitatory Amino Acid Agents; Exploratory Behavior; GABA-A Receptor Antagonists; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Sensory Gating; Sodium Channel Blockers; Tetrodotoxin; Thymine | 2012 |
Lack of association between the LRRK2 A419V variant and Asian Parkinson's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Case-Control Studies; China; Cohort Studies; Cytosine; Female; Gene Frequency; Genetic Variation; Genotype; Heterozygote; Humans; India; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Malaysia; Male; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Protein Serine-Threonine Kinases; Risk Factors; Singapore; Thymine; Valine; Young Adult | 2013 |
Electrophysiological effects of kainic acid on vasopressin-enhanced green fluorescent protein and oxytocin-monomeric red fluorescent protein 1 neurones isolated from the supraoptic nucleus in transgenic rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Alanine; Animals; Arginine Vasopressin; Cell Separation; Electric Conductivity; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Green Fluorescent Proteins; Isoxazoles; Kainic Acid; Luminescent Proteins; Neurons; Oxytocin; Patch-Clamp Techniques; Primary Cell Culture; Propionates; Rats; Rats, Transgenic; Receptors, Ionotropic Glutamate; Receptors, Kainic Acid; Red Fluorescent Protein; Supraoptic Nucleus; Thymine | 2014 |
STIM1 and SLC24A4 Are Critical for Enamel Maturation.
Topics: Alanine; Ameloblasts; Amelogenesis; Animals; Antiporters; Arginine; Calcium Signaling; Child; Child, Preschool; Consanguinity; Cysteine; Cytosine; Dental Enamel Hypoplasia; Female; Genetic Variation; Homozygote; Humans; Membrane Proteins; Mice; Mutation, Missense; Neoplasm Proteins; Pedigree; Stromal Interaction Molecule 1; Thymine; Valine | 2014 |
The limitations of diazepam as a treatment for nerve agent-induced seizures and neuropathology in rats: comparison with UBP302.
Topics: Alanine; Amygdala; Animals; Anticonvulsants; Anxiety; Diazepam; Hippocampus; Male; Nerve Degeneration; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Seizures; Soman; Status Epilepticus; Thymine | 2014 |
Further evidence for causal FAM20A mutations and first case of amelogenesis imperfecta and gingival hyperplasia syndrome in Morocco: a case report.
Topics: Alanine; Amelogenesis Imperfecta; Base Sequence; Child; Codon, Nonsense; Cytosine; Dental Enamel Proteins; Exons; Female; Fibromatosis, Gingival; Frameshift Mutation; Gingival Hyperplasia; Homozygote; Humans; Leucine; Morocco; Sequence Deletion; Syndrome; Thymine | 2015 |
Modulation of nociceptive dural input to the trigeminocervical complex through GluK1 kainate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Afferent Pathways; Alanine; Animals; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Iontophoresis; Isoquinolines; Male; Meningeal Arteries; Neurons; Nociception; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Thymine; Trigeminal Nuclei | 2015 |
The Role of Kainate Receptors in the Pathophysiology of Hypoxia-Induced Seizures in the Neonatal Mouse.
Topics: Alanine; Animals; Animals, Newborn; Disease Models, Animal; Disease Susceptibility; Electroencephalography; Hippocampus; Hypoxia; Mice; Mice, Knockout; Receptors, Kainic Acid; Seizures; Synaptic Potentials; Thymine | 2018 |
Structural and Functional Insights into GluK3-kainate Receptor Desensitization and Recovery.
Topics: Alanine; Animals; Binding Sites; Cryoelectron Microscopy; Crystallography, X-Ray; GluK3 Kainate Receptor; HEK293 Cells; Humans; Mutagenesis, Site-Directed; Polysaccharides; Protein Conformation; Rats; Receptors, Kainic Acid; Thymine | 2019 |
The kainate receptor antagonist UBP310 but not single deletion of GluK1, GluK2, or GluK3 subunits, inhibits MPTP-induced degeneration in the mouse midbrain.
Topics: Alanine; Animals; Dopaminergic Neurons; GluK2 Kainate Receptor; GluK3 Kainate Receptor; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Parkinsonian Disorders; Receptors, Kainic Acid; Thymine | 2020 |
Pharmacological antagonism of kainate receptor rescues dysfunction and loss of dopamine neurons in a mouse model of human parkin-induced toxicity.
Topics: Alanine; Animals; Disease Models, Animal; Dopaminergic Neurons; Down-Regulation; Female; GluK2 Kainate Receptor; Male; Mice; Mice, Inbred C57BL; Mutation; Parkinson Disease; Receptors, Kainic Acid; Thymine; Ubiquitin-Protein Ligases | 2020 |
Peptide nucleic acid Hoogsteen strand linker design for major groove recognition of DNA thymine bases.
Topics: Alanine; Alkenes; Base Pairing; Cross-Linking Reagents; Crystallography, X-Ray; DNA; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Nucleic Acid Conformation; Peptide Nucleic Acids; Peptides; Pyrimidines; RNA, Untranslated; Thermodynamics; Thymine | 2021 |