alanine has been researched along with thromboplastin in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (25.00) | 18.2507 |
| 2000's | 13 (65.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gibbs, CS; Law, VS; Leung, LL; Mao, CT; Paborsky, LR | 1 |
| Gibbs, CS; Leung, LL; McCurdy, SN; Paborsky, LR | 1 |
| Edgington, TS; Ruf, W; Schullek, JR | 1 |
| Edgington, TS; Ruf, W; Schullek, JR; Stone, MJ | 1 |
| Edgington, TS; Kelly, CR; Ruf, W; Schullek, JR | 1 |
| Bode, W; Camp, JT; Fuentes-Prior, P; Kane, WH; Kim, SW; Macedo-Ribeiro, S; Quinn-Allen, MA | 1 |
| Forsythe, MS; Khurana, S; Mousa, SA | 1 |
| Freskgård, PO; Nielsen, LS; Olsen, OH; Persson, E; Petersen, LC | 1 |
| Iwanaga, S; Kawabata, S; Kawasaki, H; Muta, T; Nose, T; Shimohigashi, Y | 1 |
| Bernardi, F; Camire, RM; High, KA; Marchetti, G; Pinotti, M; Pollak, ES; Tidd, T; Toso, R | 1 |
| Bode, W; Fuentes-Prior, P; Kane, WH; Macedo-Ribeiro, S; Peng, W; Quinn-Allen, MA; Saleh, M | 1 |
| Alexander, KA; Kane, WH; Kim, SW; Peng, W; Quinn-Allen, MA | 1 |
| Manithody, C; Rezaie, AR | 1 |
| Abdel-Meguid, SS; Babine, RE; Jin, L; Navaneetham, D; Pandey, P; Strickler, JE; Walsh, PN | 1 |
| Manithody, C; Rezaie, AR; Yang, L | 1 |
| Cloonan, ME; DiNapoli, M; Mousa, SA | 1 |
| Collier, ME; Ettelaie, C; Frentzou, GA; Greenman, J; Li, C | 1 |
| Autin, L; Dahlbäck, B; Steen, M; Tholander, AL; Tran, S; Villoutreix, BO | 1 |
| Collier, ME; Ettelaie, C | 1 |
| Boffito, M; Emerson, M; Gazzard, B; Khawaja, AA; Lovell, AO; Nelson, M; Taylor, KA | 1 |
20 other study(ies) available for alanine and thromboplastin
| Article | Year |
|---|---|
A peptide derived from a tissue factor loop region functions as a tissue factor--factor VIIa antagonist.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Cyclization; Escherichia coli; Factor VIIa; Gene Expression; Molecular Sequence Data; Mutagenesis; Peptide Fragments; Protein Conformation; Protein Structure, Secondary; Recombinant Fusion Proteins; Solubility; Thromboplastin | 1995 |
Identification of the factor VIIa binding site on tissue factor by homologous loop swap and alanine scanning mutagenesis.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Factor VIIa; Interferon-gamma; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Protein Conformation; Receptors, Interferon; Recombinant Proteins; Sequence Alignment; Structure-Activity Relationship; Thromboplastin | 1994 |
Key ligand interface residues in tissue factor contribute independently to factor VIIa binding.
Topics: Alanine; DNA Mutational Analysis; Factor VIIa; Factor X; Humans; Protein Binding; Recombinant Proteins; Structure-Activity Relationship; Thromboplastin | 1994 |
Mutational mapping of functional residues in tissue factor: identification of factor VII recognition determinants in both structural modules of the predicted cytokine receptor homology domain.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; CHO Cells; Cricetinae; Factor VII; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Peptide Mapping; Protein Folding; Receptors, Cytokine; Sequence Homology; Structure-Activity Relationship; Thromboplastin | 1994 |
Tissue Factor residue Asp44 regulates catalytic function of the bound proteinase Factor VIIa.
Topics: Alanine; Animals; Aspartic Acid; Binding, Competitive; Catalysis; CHO Cells; Cricetinae; DNA; Factor VIIa; Humans; Kinetics; Mutation; Peptide Hydrolases; Solubility; Structure-Activity Relationship; Thromboplastin | 1996 |
Identification of functionally important amino acid residues within the C2-domain of human factor V using alanine-scanning mutagenesis.
Topics: Alanine; Amino Acid Sequence; Antibodies, Monoclonal; Enzyme-Linked Immunosorbent Assay; Epitope Mapping; Factor V; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Protein Structure, Secondary; Protein Structure, Tertiary; Thromboplastin | 2000 |
Comparative in vitro efficacy of different platelet glycoprotein IIb/IIIa antagonists on platelet-mediated clot strength induced by tissue factor with use of thromboelastography: differentiation among glycoprotein IIb/IIIa antagonists.
Topics: Abciximab; Alanine; Amidines; Antibodies, Monoclonal; Blood Coagulation; Blood Platelets; Elasticity; Fibrin; Humans; Immunoglobulin Fab Fragments; Isoxazoles; Nephelometry and Turbidimetry; Oxazoles; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Sulfonamides; Thrombelastography; Thromboplastin; Viscosity | 2000 |
Binding of Zn2+ to a Ca2+ loop allosterically attenuates the activity of factor VIIa and reduces its affinity for tissue factor.
Topics: Alanine; Allosteric Site; Amino Acid Chloromethyl Ketones; Binding Sites; Calcium; Catalytic Domain; Dose-Response Relationship, Drug; Factor VIIa; Histidine; Humans; Ions; Kinetics; Models, Molecular; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Surface Plasmon Resonance; Thromboplastin; Time Factors; Zinc | 2000 |
Head-to-tail polymerization of coagulin, a clottable protein of the horseshoe crab.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Horseshoe Crabs; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Peptide Biosynthesis; Peptides; Protein Binding; Protein Structure, Tertiary; Surface Plasmon Resonance; Thromboplastin; Time Factors; Tyrosine; X-Rays | 2000 |
Factor VII mutant V154G models a zymogen-like form of factor VIIa.
Topics: Alanine; Amino Acid Chloromethyl Ketones; Binding Sites; Enzyme Precursors; Factor VII; Factor VIIa; Humans; Isoleucine; Point Mutation; Protein Conformation; Serine Proteinase Inhibitors; Thromboplastin; Valine | 2003 |
The factor V C1 domain is involved in membrane binding: identification of functionally important amino acid residues within the C1 domain of factor V using alanine scanning mutagenesis.
Topics: Alanine; Amino Acid Sequence; Animals; Cell Membrane; COS Cells; Culture Media, Conditioned; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Factor V; Fluorescence Resonance Energy Transfer; Humans; Kinetics; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphatidylserines; Phospholipids; Protein Binding; Protein Structure, Tertiary; Thromboplastin | 2004 |
Trp2063 and Trp2064 in the factor Va C2 domain are required for high-affinity binding to phospholipid membranes but not for assembly of the prothrombinase complex.
Topics: Alanine; Amino Acid Substitution; Animals; Cattle; Cell Line; COS Cells; Factor Va; Fluorescence Resonance Energy Transfer; Humans; Lipid Bilayers; Moths; Phosphatidylserines; Phospholipids; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Proteins; Surface Plasmon Resonance; Thromboplastin; Tryptophan | 2004 |
Functional mapping of charged residues of the 82-116 sequence in factor Xa: evidence that lysine 96 is a factor Va independent recognition site for prothrombin in the prothrombinase complex.
Topics: Alanine; Amides; Antithrombins; Catalysis; Cell Line; Factor Va; Factor Xa; Factor Xa Inhibitors; Humans; Hydrolysis; Lysine; Peptide Fragments; Peptide Mapping; Protein Structure, Tertiary; Prothrombin; Substrate Specificity; Thromboplastin | 2005 |
Structural and mutational analyses of the molecular interactions between the catalytic domain of factor XIa and the Kunitz protease inhibitor domain of protease nexin 2.
Topics: Alanine; Alzheimer Disease; Arginine; Binding Sites; Carrier Proteins; Catalytic Domain; Crystallography, X-Ray; Disulfides; DNA Mutational Analysis; Dose-Response Relationship, Drug; Factor XIa; Humans; Inhibitory Concentration 50; Kinetics; Lysine; Models, Molecular; Models, Statistical; Mutation; Partial Thromboplastin Time; Phenylalanine; Plasmids; Point Mutation; Proline; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Serine; Serine Proteinase Inhibitors; Structure-Activity Relationship; Thromboplastin; Time Factors; Vesicular Transport Proteins | 2005 |
Identification of a basic region on tissue factor that interacts with the first epidermal growth factor-like domain of factor X.
Topics: Alanine; Amino Acid Substitution; Arginine; Asparagine; Epidermal Growth Factor; Factor VIIa; Factor X; Humans; Lysine; Models, Molecular; Protein Structure, Tertiary; Thromboplastin | 2007 |
Efficacy of anticoagulants and platelet inhibitors in cancer-induced thrombosis.
Topics: Alanine; Cell Line, Tumor; Drug Therapy, Combination; Enoxaparin; Heparin, Low-Molecular-Weight; Humans; Neoplasms; Oxazoles; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombelastography; Thromboplastin; Thrombosis; Tinzaparin | 2007 |
Investigation of the mechanisms of tissue factor-mediated evasion of tumour cells from cellular cytotoxicity.
Topics: Alanine; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Immune System; Models, Biological; Mutagenesis, Site-Directed; Neoplasm Metastasis; Peptides; Phosphorylation; Protein Structure, Tertiary; Serine; Thromboplastin; Transfection; Vascular Cell Adhesion Molecule-1 | 2008 |
Mapping of the factor Xa binding site on factor Va by site-directed mutagenesis.
Topics: Alanine; Animals; Binding Sites; Chlorocebus aethiops; COS Cells; Factor Va; Factor Xa; Humans; Kinetics; Mutagenesis, Site-Directed; Mutation; Protein Binding; Prothrombin; Thermodynamics; Thromboplastin | 2008 |
Regulation of the incorporation of tissue factor into microparticles by serine phosphorylation of the cytoplasmic domain of tissue factor.
Topics: Alanine; Apoptosis; Aspartic Acid; Blotting, Western; Cell-Derived Microparticles; Cells, Cultured; Humans; Oligopeptides; Phosphorylation; Serine; Signal Transduction; Thromboplastin | 2011 |
HIV Antivirals Affect Endothelial Activation and Endothelial-Platelet Crosstalk.
Topics: 5'-Nucleotidase; Adenine; Alanine; Anti-HIV Agents; Apyrase; Blood Platelets; Cell Adhesion Molecules; Cell Communication; Cell-Derived Microparticles; Cells, Cultured; Dideoxynucleosides; Endothelial Cells; GPI-Linked Proteins; Human Umbilical Vein Endothelial Cells; Humans; Platelet Activation; Signal Transduction; Tenofovir; Thromboplastin | 2020 |