alanine has been researched along with threonine in 1046 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 424 (40.54) | 18.7374 |
| 1990's | 157 (15.01) | 18.2507 |
| 2000's | 322 (30.78) | 29.6817 |
| 2010's | 115 (10.99) | 24.3611 |
| 2020's | 28 (2.68) | 2.80 |
| Authors | Studies |
|---|---|
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S | 1 |
| Prasad, M | 1 |
| Kieras, FJ | 1 |
| Banik, AK; Majumdar, SK | 1 |
| Ponnamperuma, C; Sweeney, MA; Toste, AP | 1 |
| Perkins, SJ; Richarz, R; Wagner, G; Wüthrich, K | 1 |
| Ashman, PU; Newport, GR; Page, CR; Seed, JR; Stibbs, HH | 1 |
| Albani, M; Ishikura, H; Kersten, H; Murao, K | 1 |
| Morihara, K; Oka, T; Tsuzuki, H | 1 |
| Biondi, A; Biondi, G; Gallone, U; Padula, P; Pignero, A; Quagliuolo, L | 1 |
| Davidson, CS; Fernstrom, JD; Hammarstrom-Wiklund, B; Munro, HN; Rand, WM; Wurtman, RJ | 1 |
| Downs, F; Murty, VL; Peterson, C; Pigman, W | 1 |
| Bouchilloux, S; Granier, C; Ronin, C; van Rietschoten, J | 1 |
| Takahashi, S; Yabu, K | 1 |
| Beccaria, L; Chiumello, G; Gianazza, E; Luppis, B; Righetti, PG | 1 |
| Deutsch, HF; Fett, JW | 1 |
| Hebeler, BH; Young, FE | 1 |
| Hasegawa, T; Ishikura, H; Murao, K | 1 |
| Bury, KD; Grayston, M; Kanarens, J | 1 |
| Gaull, GE; Heinonen, K; Räih, NC; Rassin, DK | 1 |
| Bumpus, FM; Hall, MM; Khairallah, PA; Khosla, MC; Muñoz-Ramírez, H | 1 |
| Chavancy, G; Fournier, A; Garel, JP | 1 |
| Davis, L; Kapke, G | 1 |
| Brimhall, B; Dresler, SL; Jones, RT | 1 |
| Korvatskiĭ, BG | 1 |
| Harper, AE; Maruyama, K; Sunde, ML | 1 |
| Lowe, NR; Robinson, C; Weatherell, JA | 1 |
| Hayes, ML; Hyatt, AT | 1 |
| Barker, JL; Nicoll, RA; Padjen, A | 1 |
| Hinoo, H; Koizumi, K; Mayama, M; Shoji, J; Wakisaka, Y | 1 |
| Chellemi, F | 1 |
| DeVries, AL; Lin, Y; Raymond, JA | 1 |
| Pritchard, DG; Schnute, WC; Todd, CW | 1 |
| Balikcioglu, S; Behnken, L; Besser, H; Förster, FJ; Grosshans, E; Neufahrt, A; Nowicki, L | 1 |
| Baetz, AL; Graham, CK; Hubbert, WT | 1 |
| Gundalakh, AI; Mel'k, MV; Shcheglova, SA; Volkova, ZA | 1 |
| Fein, JE; MacLeod, RA | 1 |
| Fendler, JH; Nagyvary, J; Nome, F | 1 |
| Guadalix, FJ; Ruiz, MC | 1 |
| Benassi, CA; Guggi, A; Rocchi, R; Salvadori, S; Tomatis, R | 1 |
| Garber, AJ; Karl, IE; Kipnis, DM | 1 |
| Heinrich, D; Kubli, F; Metz, J; Wesch, H | 1 |
| Akasaka, T; Ono, N; Sawai, T; Yamaguchi, A | 1 |
| Faden, AI | 1 |
| Aulak, K; Bissler, J; Davis, AE; Eldering, E; Hack, CE; Kramer, J; Parad, RB; Rosen, FS; Stecklein, HP; Strunk, RC | 1 |
| Felton, JS; Jägerstad, M; Knize, MG; Skog, K | 1 |
| Maenz, DD; Patience, JF | 1 |
| Lee, GJ; McFadden, BA | 1 |
| Ata, K; Bouhassira, EE; Kanzaki, A; Nagel, RL; Qiu, JJ; Rybicki, AC; Schwartz, RS; Yawata, Y | 1 |
| Hitch, DC; Kubota, A; Meguid, MM | 1 |
| Bradley, TM; Lo, YH; Rhoads, DE | 1 |
| Greenhalgh, DA; Khorana, HG; Rath, P; Rothschild, KJ; Subramaniam, S | 1 |
| Behar, KL; Ogino, T | 1 |
| Frauendienst-Egger, G; Fukao, T; Hashimoto, T; Orii, T; Osumi, T; Schrod, L; Tomatsu, S; Yamaguchi, S | 1 |
| Altenhofen, W; Bönigk, W; Eismann, E; Kaupp, UB; Kraus, W; Ludwig, J | 1 |
| Angelaccio, S; Bossa, F; Fattori, E; Pascarella, S; Schirch, V; Strong, W | 1 |
| Martinis, SA; Poulos, TL; Raag, R; Sligar, SG | 1 |
| Hashimoto, T; Kuriyama, K; Matsumoto, K; Ueda, S | 1 |
| Arbus, GS; Goldberg, DM; Ish-Shalom, N; Macpherson, NA; Moscarello, MA | 1 |
| Carrell, RW; Daly, M; Harper, PL; Perry, DJ; Price, J; Tait, RC; Walker, ID | 1 |
| Rogers, QR; Spensley, MS; Willits, NH; Zicker, SC | 1 |
| Barbato, G; Bax, A; Ikura, M; Kay, LE; Krinks, M; Spera, S | 1 |
| Blench, I; Freyssinet, JM; Grunebaum, L; Ireland, H; Lane, DA; Morris, HR; Olds, R; Thein, SL; Thompson, E; Walker, ID | 1 |
| Brennan, SO; Donaldson, D; George, PM; Myles, T; Peach, RJ | 1 |
| LeMaster, DM; Markley, JL; Wang, JF | 1 |
| Beg, OU; Brewer, HB; Brunzell, JD; Fojo, SS; Meng, MS; Previato, L; Skarlatos, SI | 1 |
| Sakharova, IS; Torchinsky, YM; Zakomirdina, LN | 1 |
| Altland, K; Benson, MD; Koeppen, AH; Wallace, MR | 1 |
| Adjadj, E; Dimicoli, JL; Favaudon, V; Lhoste, JM; Mispelter, J; Quiniou, E | 1 |
| Ghislain, M; Goffeau, A; Petretski, JH; Rodrigues Júnior, G; Schlesser, A; Van Dyck, L; Wolosker, H | 1 |
| Corbin, JD; Ng, L; Shabb, JB | 1 |
| Chen, WS; Gill, GN; Herbst, JJ; Lazar, CS; Lund, KA; Rosenfeld, MG; Walsh, BJ; Walton, GM; Welsh, JB; Wiley, HS | 1 |
| Horiuchi, T; Imai, M; Ishimura, Y; Koga, H; Makino, R; Matsushima-Hibiya, Y; Shimada, H; Watanabe, Y | 1 |
| Kantrowitz, ER; Xu, W | 1 |
| Countaway, JL; Davis, RJ; Northwood, IC | 1 |
| Corbin, JD; Shabb, JB; Weber, IT | 1 |
| Fong, YL; Means, AR; Soderling, TR; Taylor, WL | 1 |
| Daly, MP; Demediuk, P; Faden, AI | 1 |
| Askanazi, J; Elwyn, DH; Gil, KM; Gump, FE; Kinney, JM; Starker, PM | 1 |
| Mercer, JR; Silva, SV | 1 |
| Kemp, BE; Michnoff, CH; Stull, JT | 1 |
| Mora, F; Peinado, JM | 1 |
| Carpenter, CD; Chen, WS; Evans, RM; Gill, GN; Lazar, CS; Lin, CR; Rosenfeld, MG | 1 |
| Basova, NA; Kushak, RI | 1 |
| Christensen, HN; Flickinger, KS; Pisoni, RL; Thoene, JG | 1 |
| Sakata, Y | 1 |
| Hashimoto, RK; Hiraga, S; Maeda, H; Ogura, T; Uzawa, H | 1 |
| Hama, H; Shimamoto, T; Tsuchiya, T; Tsuda, M | 1 |
| Arme, C; Jeffs, SA | 1 |
| Driessen, AJ; Konings, WN; Russell, JB; Strobel, HJ | 1 |
| Bass, S; Sorrells, V; Youderian, P | 1 |
| Sangiah, S | 1 |
| Harper, AE; Nguyen, H; Repa, JJ; Tews, JK | 1 |
| Christensen, HN; Vadgama, JV | 1 |
| Longbottom, JL; Pepys, J | 1 |
| Bryce, GF | 1 |
| Orlova, TI; Silaev, AB; Sorokina, NV | 1 |
| Asghar, SS; Harold, FM; Levin, E | 1 |
| Abeles, RH; Krodel, E; Massey, V; Walsh, CT | 1 |
| Aprison, MH; Daly, E; McBride, WJ | 1 |
| Morris, I; Slater, JH | 1 |
| Colley, L; Fox, FR; Huggins, AK | 1 |
| Kasarian, BA | 1 |
| Jaton, JC | 1 |
| Givol, D; Rüde, E | 1 |
| Bundgaard, L; Winther, A | 1 |
| Grimble, RF; Whitehead, RG | 3 |
| Murray, CL; Rabinowitz, JC; Samuel, CE | 1 |
| Deutscher, MP; Hilderman, RH | 1 |
| Braun, W; Weiss, C; Zschaler, W | 1 |
| Davidson, EA; Hranisavljevic, J; Simpson, DL | 1 |
| Hallberg, D; Soda, M | 1 |
| Herbert, E; Smith, CJ | 1 |
| Manahan, J; Mandl, I | 2 |
| Hirsh, DI; Lipmann, F | 1 |
| Bell, FE; Owens, SL | 1 |
| Asano, Y; Fukui, A; Sinoara, H | 1 |
| Ghendon, YZ; Mikhejeva, A; Yakobson, E | 1 |
| Anderson, RS; Close, DM | 1 |
| Crippa, PR; Tedeschi, RA; Vecli, A | 1 |
| Kleinkauf, H; Ristow, H; Salnikow, J | 1 |
| Ikenaka, T; Murao, S; Nabeshima, Y; Odani, S; Sakai, M; Sato, S | 1 |
| Anderer, FA; Wittmann, HG; Wittmann-Liebold, B | 1 |
| Miyajima, R; Otsuka, S; Shiio, I | 1 |
| Moat, AG; Thomulka, KW | 1 |
| Read, CP; Southworth, GC | 1 |
| Yamamoto, M; Young, JL | 1 |
| Cooper, MR; DeChatelet, LR; McCall, CE | 1 |
| Aktin, E; Bergisadi, N; Güven, KC; Koyuncuoglu, H | 1 |
| Mandel, P; Trayhurn, P; Virmaux, N | 1 |
| Draper, P | 1 |
| Allsopp, MN; Hullin, RP; Rees, JR | 1 |
| Asafov, GB; Ekisenina, NI; Ivanova, LM; Lumel'skiĭ, VIa; Smagin, VG | 1 |
| Schwarz, E | 1 |
| Maier, R; Riniker, B; Rittel, W | 1 |
| Hass, LF; Jarboe, CJ; Noll, BW | 2 |
| Lindig, OH; Mitlin, N; Thompson, AC; Wiygul, G | 1 |
| Jäkel, A; Liappis, N | 1 |
| Crossley, AC; Evans, PD | 1 |
| Faulstich, H; Heber, H; Wieland, T | 1 |
| Alderson, NE; Amos, HE; Boling, JA; Ely, DG; Goshtasbpour-Parsi, BG | 1 |
| Friedmann, N; Miller, SL; Ring, D; Wolman, Y | 1 |
| Brimhall, B; Dresler, SL; Jones, RT; Runkel, D; Stenzel, P | 1 |
| Markussen, J; Sundby, F | 1 |
| Kreil, G | 1 |
| Miller, EJ | 1 |
| Draper, P; Rees, RJ | 1 |
| Sunde, ML | 1 |
| Oxender, DL; Robbins, JC | 1 |
| Claus, DR; Oxender, DL; Rahmanian, M | 1 |
| De Felice, M; Guardiola, J; Iaccarino, M; Klopotowski, T | 2 |
| Hayaishi, O; Inoue, K; Kurosawa, A; Shizuta, Y; Tanabe, T | 1 |
| Mage, RG | 1 |
| Savageau, MA; Templeton, BA | 1 |
| Halpern, YS | 1 |
| Edmunds, LN; Sulzman, FM | 1 |
| Fekl, W | 1 |
| Rees, MW; Short, MN | 1 |
| Coulson, RA; Herbert, JD | 1 |
| Araya, A; Goodman, M; Maita, T; Matsuda, G; Ota, H; Prychodko, W; Watanabe, B | 1 |
| Ando, T; Suzuki, K | 2 |
| Flores, JJ; Ponnamperuma, C | 1 |
| Okano, T; Sato, Y | 1 |
| Davis, JM; Plaut, SM | 1 |
| Meister, A; Palekar, AG; Tate, SS | 1 |
| Hsueh, HW; Moskowitz, M | 1 |
| Yu, WL | 1 |
| Kaplan, JG; McDonald, RA | 1 |
| Gutman, AB; Yu, TF | 2 |
| Gruber, L; Harris, JE | 1 |
| Dembinski, A; Konturek, SJ; Radecki, T; Thor, P | 1 |
| Christiansen, PA; Reiser, S | 2 |
| Derevitskaya, VA; Kochetokov, NK; Likhosherstov, LM; Medvedev, SA; Zelinsky, ND | 1 |
| Adibi, SA; Amin, PM; Modesto, TA; Morse, EL | 1 |
| Bemiller, JN; Hoffmann, WE; Pappelis, AJ | 1 |
| Bender, ML; Valenzuela, P | 1 |
| Appella, E; Carta-Sorcino, M; Inman, JK; Mage, R | 1 |
| Lowenstein, LM; Mayers, AM; Toback, FG | 1 |
| Dobrev, ID; Krysteva, MA; Mancheva, IN | 1 |
| Hook, DJ; Vining, LC | 1 |
| Iivanainen, M; Palo, J; Savolainen, H | 1 |
| Bajaj, VR; Kapoor, U; Singh, PI | 1 |
| Mobley, WC; Moore, JB; Shooter, EM | 1 |
| Okada, M; Suzuki, K | 1 |
| Bernstein, IA; Gray, RH; Sibrack, LA | 1 |
| Hart, JW; Johnson, RJ | 1 |
| Jörnvall, H; Ohlsson, H; Philipson, L | 1 |
| Giorgio, AJ; Linarelli, LG; Macdonald, RR; Rubin, HM | 1 |
| Doores, L; Schulman, JD; Silagi, S; Wrathall, JR | 1 |
| Anandaraj, MP; Cherayil, JD | 1 |
| Kaback, HR; Stadtman, ER | 1 |
| Agrawal, HC; Davis, JM; Himwich, WA | 1 |
| Iwatani, A; Izui, K; Katsuki, H; Nishikido, T; Tanaka, S | 1 |
| Berger, H; Yanofsky, C | 1 |
| Sekiya, T; Ukita, T | 1 |
| Degani, Y; Patchornik, A; Spande, TF; Witkop, B | 1 |
| Elfving, R; Raunio, R | 1 |
| Milne, MD | 1 |
| Hampton, JR | 1 |
| Hunt, DE | 2 |
| Feder, J | 1 |
| Doi, RH; Horikoshi, K | 1 |
| Kojima, H; Sugae, K | 1 |
| Mikes, O; Sorm, F; Toan, NB; Turková, J | 1 |
| Doi, RH; Migita, LK | 1 |
| Cahill, CF; Felig, P; Marliss, E; Ohman, JL | 1 |
| Baumgarten, J; Schlegel, HG | 1 |
| Abel, CA; Grey, HM; Prahl, JW | 1 |
| Cicmanec, J; Koll, M; Seaman, GR | 1 |
| Dewey, VC; Kidder, GW | 1 |
| Okaju, M; Shapshak, P | 1 |
| Cohen HP LIN, S | 1 |
| Ayala, GF; Cohen, HP; Vasconetto, C | 1 |
| Arkin-Shlank, H; Cavari, BZ; Grossowicz, N | 1 |
| Felig, P; Hendler, R; Kim, YJ; Lynch, V | 1 |
| De Vries, AL; Lin, Y; Shier, WT | 1 |
| Cheyne, GA; Hytten, FE | 1 |
| Burdman, JA | 1 |
| Panksepp, J | 1 |
| Furuchi, A; Tokunaga, T | 1 |
| Boling, JA; Bradley, NW; Willard, JC | 1 |
| Hafez, ES; Jaszczak, S | 1 |
| Hladny, J; Kandler, O; Schleifer, KH | 1 |
| Morishita, S; Muramatsu, K; Odagiri, H; Takeuchi, H | 1 |
| Ono, T; Tasaki, I | 1 |
| Campbell, DJ; Reid, DW; Yakymyshyn, LY | 1 |
| Brummel, MC; Sanborn, BM; Stegink, LD | 1 |
| Karabin, L; Szczepanowska, M; Szcześniak, T; Wituch, K | 1 |
| Fairwell, T; Lovins, RE | 1 |
| Fernstrom, JD; Larin, F; Wurtman, RJ | 1 |
| Shearer, TR; Suttie, JW | 1 |
| Christensen, HN; Koser, BH | 1 |
| Hornig, D; Weber, F; Wiss, O | 1 |
| Freinkel, N; Hare, JW; Metzger, BE | 1 |
| Markelova, SI; Zharikova, GG | 3 |
| Ermol'eva, ZV; Kolosova, IV; Pasternak, NA; Pokidova, NV; Shenderovich, VA | 1 |
| Haufe, F; Haufe, U; Lubs, H; Machill, G | 1 |
| Brummel, MC; Sanborn, BM; Stegink, LD; Vestling, CS | 1 |
| Buck, CA; Granger, GA; Holland, JJ; Taylor, MW | 1 |
| Kotelchuck, D; Scheraga, HA | 1 |
| Hellman, A; Hellman, KB; Martin, DH; Novelli, GD; Yang, WK | 1 |
| Geisler, C; Höcker, P; Stacher, A; Wiser, M | 1 |
| Gerron, GG; Howard, CH; Rudman, D; Vogler, WR | 1 |
| Banerjee, M; Banerjee, SN; Horsley, RJ | 1 |
| Dunnill, PM; Fowden, L | 1 |
| Appella, E; Martin, RG; Voll, MJ | 1 |
| Khorana, HG; Morgan, AR; Wells, RD | 1 |
| Barois, A; Caldera, R; Escourolle, R; Goulon, M; Grosbuis, S; Nouailhat, F | 1 |
| Ebata, M; Miyazaki, K; Otsuka, H | 1 |
| Kapoor, IJ; Tandon, RN | 1 |
| Dusek, Z; Hradec, J | 1 |
| Bruneteau, M; Martin, A; Michel, G | 1 |
| Hoshino, S; Tsubota, H | 1 |
| Ermol'eva, ZV; Pokidova, NV; Zhuravleva, TP | 1 |
| Fuchs, G; Oepen, H; Oepen, I | 1 |
| Hatano, M; Obara, Y; Ono, S | 1 |
| Griffin, GE; Kesner, L; Muntwyler, E; Sanslone, WR | 1 |
| Manchester, KL | 1 |
| Berg, WE; Mertes, DH | 1 |
| Berl, S; Santini, M | 1 |
| Palo, J; Saifer, A | 1 |
| Lanks, KW | 1 |
| Ermol'eva, ZV; Evseenko, LK; Iulikova, EP; Kolosova, IV; Pasternak, NA; Pokidova, NV; Shenderovich, VA; Silaev, AB | 1 |
| Lohrenz, FN; Tewksbury, DA | 1 |
| Bowman, RL; Ito, Y; Pisano, JJ; Tanimura, T | 1 |
| Fredrickson, DS; Herbert, P; LaRosa, JC; Levy, RI; Lux, SE | 1 |
| Hill, RJ; Naughton, MA; Wake, RG | 1 |
| Haber, E; Waterfield, M | 1 |
| Carton, D; De Schrijver, F; Delbeke, MJ; Dhondt, F; Hooft, C; Kint, J; Samyn, W | 1 |
| Neuhoff, V; Weise, M | 1 |
| Nobel, PS; Wang, CT | 1 |
| A'Zary, E; Saifer, A; Schneck, L; Valenti, C | 1 |
| Christensen, HN; Thomas, EL | 1 |
| Alaupovic, P; Furman, RH; McConathy, WJ; Seidel, D | 1 |
| Brunner, CE; Bryan, JK; Bryan, PA; Cawley, RD | 1 |
| Fürst, P; Josephson, B; Vinnars, E | 1 |
| DeVries, AL; Feeney, RE; Komatsu, SK | 1 |
| DeVries, AL; Feeney, RE; Komatsu, S | 1 |
| Baranova, IP; Egorov, NS | 1 |
| Anderson, JW; Fowden, L | 1 |
| Kearney, EB; Kenney, WC; Singer, TP; Walker, WH; Zeszotek, E | 1 |
| Linkswiler, H; Park, YK | 1 |
| Tauschel, HD | 1 |
| Balasubramanian, M; Myers, RF | 1 |
| Kerly, M; Spruyt, JE | 1 |
| Frolova, VI; Katrukha, GS; Kuzovkov, AD | 1 |
| Diller, A; Schirch, LV | 1 |
| Flory, B; Krassner, SM | 1 |
| Forest, JC; Wightman, F | 1 |
| Debusk, AG; Wolfinbarger, L | 1 |
| Hopkins, L; McFadyen, IR; Young, M | 1 |
| Kloss, G; Schwarz, E | 1 |
| Bubenshchikova, SN; Katrukha, GS; Kharchenko, LI; Silaev, AB; Trufonova, ZhP | 1 |
| Kickuth, R; Scheffer, F; Schlimme, E | 1 |
| Gusev, EI | 1 |
| Ansorge, S; Bohley, P | 1 |
| Demeyer, DI; Henderickx, HK | 1 |
| Roberts, WS; Söll, D; Strominger, JL | 1 |
| Bartelt, DC; DiCarlo, JJ; Greene, LJ; Sussman, AJ | 1 |
| Gray, E; Paulus, H | 1 |
| Björnesjö, KB | 1 |
| Blumenfeld, OO; Gallop, PM; Henson, E; Schneider, AL | 1 |
| Björenesjö, KB | 1 |
| Bodanszky, A; Bodanszky, M; Doubler, MR; Lukin, M; Muramatsu, I | 1 |
| Maeda, K; Muraoka, Y; Takita, T; Umezawa, H | 1 |
| Brown, HH | 1 |
| Bonner, J; DeLange, RJ; Fambrough, DM; Smith, EL | 1 |
| Bairos, MA; Bairos, VA | 1 |
| Eaton, SW; Vernon, RG; Walker, DG | 1 |
| Barabás, G; Szabó, G | 1 |
| Holcomb, GN; James, SA; Lamkin, WM; Wade, J; Ward, DN | 1 |
| Ota, S | 1 |
| Killilea, SD; O'Carra, P | 1 |
| Samofalova, MS | 1 |
| Farid, SA; Kozloff, LM | 1 |
| Hanson, H; Kettmann, U; Kretschmer, K | 1 |
| Beyer, H; Schenk, U | 1 |
| Oravec, M; Sourkes, TL | 1 |
| Landau, RL; Lugibihl, K | 2 |
| McCalla, AG; Yang, HJ | 1 |
| Beisel, WR; Dangerfield, HG; Feigin, RD | 1 |
| Pine, MJ; Sarimo, SS | 1 |
| Berge, T; Borgfors, N; Brun, A; von Studnitz, W | 1 |
| Gross, S; Maskaleris, ML; Milhorat, AT | 1 |
| Tsuzuki, J | 1 |
| Abdel Kader, MM; Abdel Wahab, F; Ata, AA; Emara, SH; Soliman, L | 1 |
| Burzyński, S; Czerniak, Z | 1 |
| Honda, I; Kanaoka, M; Naruse, M; Sakakibara, S | 1 |
| Kane, J; Karakawa, WW; Krause, RM; Lackland, H | 1 |
| Gordon, WG; Greenberg, R; Pepper, L; Thompson, MP | 1 |
| Carruthers, C | 1 |
| McCormick, DB; Sigel, H; Wright, LD | 1 |
| Gineitis, AA; Vinogradova, IA; Vorobyev, VI | 1 |
| Koshiyama, I | 1 |
| Naftalin, L; Stephens, A | 1 |
| Ikehara, M; Ohtsuka, E | 1 |
| McEvoy-Bowe, E; Sarojini Thevi, S | 1 |
| Dennis, ES; Goodchild, CG | 1 |
| Herbert, E; Smith, CJ; Smith, PM | 1 |
| Huang, JM; Wang, IS; Wang, KT | 1 |
| Christian, JH; Waltho, JA | 1 |
| Mepham, TB; Smith, MW | 1 |
| Fujita, T; Hoshino, O; Ikekawa, N; Orimo, H; Watanuki, R; Yoshikawa, M | 1 |
| Gurley, LR; Kischer, CW; Shepherd, GR | 1 |
| Ebata, M; Otsuka, H; Takahashi, Y | 1 |
| Aurich, H | 1 |
| Gutermann, H; Waldschmidt-Leitz, E | 1 |
| Pogorelova, TN | 1 |
| Frolova, VI; Iulikova, EP; Kuzovkov, AD; Oparysheva, EF | 1 |
| Marutian, SA | 1 |
| Andreeva, LA | 1 |
| Carver, MJ; Ryan, WL | 1 |
| Pitts, RF; Stone, WJ | 1 |
| Bourke, JB; Massey, LM; Stillings, BR | 1 |
| Adamson, LF; Ingbar, SH | 1 |
| Kathan, RH; Reichert, LE; Ryan, RJ | 1 |
| Bellamy, D; Dulieu, K; Leonard, RA | 1 |
| Mohri, T | 1 |
| Estes, FL; Wetzel, RL | 1 |
| Kuttner, RE; Lorincz, AB; Portoghese, A | 1 |
| Harper, E; Scharrer, B; Seifter, S | 1 |
| Efron, ML; Mechanic, GL; Shih, VE | 1 |
| Lopes-Vieira, O; Walker, B; Williamson, DH | 1 |
| Oliver, IT; Yeung, D | 1 |
| Abasov, IT | 1 |
| Agnihotri, VP; Vaartaja, O | 1 |
| Cook, CF; Leibholz, J | 1 |
| Kuroda, Y | 1 |
| Brown, M; Dharmsathaphorn, K; Rivier, J; Rosenthal, LE; Vale, W; Yamashiro, DJ | 1 |
| Bhatnagar, R; Chauhan, BS; Desai, NC; Garg, SP | 1 |
| Mora, F; Myers, RD; Peinado, JM | 1 |
| Huisman, TH; Lam, H; Nakatsuji, T | 1 |
| Aoki, N; Iwanaga, S; Miyata, T; Sakata, Y | 1 |
| Demigne, C; Fafournoux, P; Remesy, C | 1 |
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| Caballero-Guerrero, B; Jiménez, E; Jiménez-Díaz, R; Maldonado-Barragán, A; Rodríguez, JM; Ruiz-Barba, JL | 1 |
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| Chen, X; Chen, XC; Du, XB; Du, XX; Kan, B; Li, HX; Li, J; Peng, XC; Wang, L; Wang, YS; Wei, YQ; Wen, YJ; Xu, JR; Yan, F; Ye, B; Yi, T; Zhao, JM; Zhao, X; Zhao, XY | 1 |
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| Cote, G; Grubbs, EG; Habra, MA; Hu, MI; Jasim, S; Jimenez, C; Rich, TA; Waguespack, SG; Ying, AK | 1 |
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| Aragonés, A; Argente, J; Azriel, S; Campos-Barros, A; García-Herrero, CM; Gutierrez-Nogués, A; Navas, MA; Rubio-Cabezas, O; Vincent, O | 1 |
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| Amdani, S; Cummings, DF; Ericksen, SS; Schetz, JA; Teer, ME | 1 |
| Chen, Y; Ding, ZT; Jiang, YP; Lan, DM; Liu, FT; Ren, HM; Wang, J; Wu, JJ; Yue, ZY; Zhao, J | 1 |
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| Grüber, G; Hunke, C; Manimekalai, MS; Sundararaman, L; Tadwal, VS | 1 |
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| Cao, Y; Du, J; Fu, L; Huang, X; Wang, L; Xu, J; Zhang, A; Zhang, Z; Zheng, Q | 1 |
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| Aller, R; Conde, R; de Luis, DA; Gonzalez Sagrado, M; Izaola, O | 1 |
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| Dadheech, S; Hussien, MD; Jain, S; Jyothy, A; Munshi, A; Rao, AV; Shaheen, U | 1 |
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| Costa, JD; Crispim, D; Dora, JM; Leiria, LB; Lopes, MG; Maia, AL; Pinto Ribeiro, RV; Vitali da Silva, A; Wajner, SM | 1 |
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| Bhullar, RP; Billakanti, R; Chelikani, P; Loewen, MC; Pydi, SP; Sobotkiewicz, T | 1 |
| Barada, K; El-Rifai, O; Estiphan, TA; Majarian, T; Rida, K; Usta, J; Wehbeh, A | 1 |
| Ashton, NW; Bolderson, E; Box, JK; Croft, LV; O'Byrne, KJ; Paquet, N; Richard, DJ; Suraweera, A; Urquhart, AJ; Zhang, SD | 1 |
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| Bauzon, F; Bi, E; Cui, J; Fu, H; Jeon, H; Lu, Z; Ye, BH; Yu, JJ; Zang, X; Zhao, H; Zhu, L | 1 |
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| Fujinaga, M; Furutsuka, K; Hashimoto, H; Hatori, A; Kawamura, K; Kumata, K; Nengaki, N; Shimoda, Y; Shiomi, S; Takei, M; Wakizaka, H; Xie, L; Yamasaki, T; Yui, J; Zhang, MR | 1 |
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| Choe, YJ; Hartl, FU; Hassemer, T; Hayer-Hartl, M; Körner, R; Park, SH; Vincenz-Donnelly, L | 1 |
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| Feng, LQ; Huang, X; Huang, YM; Jiang, YQ; Li, HY; Patil, S; Qin, Y; Tian, GB; Xing, Y; Zeng, KJ; Zhang, XF; Zhong, LL | 1 |
| Fu, YH; Hallows, WC; Hirano, A; Jones, CR; Lipzen, A; McMahon, T; Pennacchio, LA; Ptáček, LJ; Shi, G; Xu, Y; Yamazaki, M | 1 |
| Abo-Elmatty, DM; Ghattas, MH; Khattab, SA; Mehanna, ET; Mesbah, NM | 1 |
| Boddeke, HW; Copray, JC; Ferrari, MF; Melo, TQ; van Zomeren, KC | 1 |
| Jin, AL; Xie, XR; Yang, YM | 1 |
| Belfort, G; Chacko, AR; Das, P | 1 |
| Bosma, T; de Vries, L; de Vries, MP; Kuipers, A; Moll, GN; Rink, R | 1 |
| Bagnoli, S; Berti, V; Ferrari, C; Ginestroni, A; Lombardi, G; Lucidi, G; Moretti, M; Nacmias, B; Piaceri, I; Polito, C; Pupi, A; Sorbi, S; Tedde, A | 1 |
| Arbibe, L; Baleux, F; Chhuon, C; Guerrera, IC; Jang, SM; Lipecka, J; Meijer, BM; Muchardt, C; Reisacher, C; Sansonetti, PJ | 1 |
| Gagnon, F; Kassam, I; Medina-Rivera, A; Morange, PE; Trégouët, DA; Wilson, MD; Zwingerman, N | 1 |
| Fujihara, A; Maeda, N | 1 |
| Frost, A; Hickey, KL; Hussmann, JA; Kostova, KK; Osuna, BA; Weinberg, DE; Weissman, JS | 1 |
| Baxter, AG; Blumenthal, A; Dobos, KM; Lucas, M; Schultz, TE; Wiesmüller, KH | 1 |
| He, F; Li, C; Li, X; Wang, X; Xue, M; Zhao, M | 1 |
| Kattula, B; Kuncha, SK; Mazeed, M; Routh, SB; Sankaranarayanan, R; Singh, R | 1 |
| Bennett, DA; Bianco, AC; Chaker, L; Evans, DA; Jo, S; Mash, DC; McAninch, EA; Peeters, RP; Rajan, KB | 1 |
| Dai, L; Kuang, S; Li, J; Rao, Z; Tang, X; Yang, L; Zhong, H; Zhong, Z | 1 |
| Aida, I; Aouichat-Bouguerra, S; Belhocine, K; Boussafsaf, MA; Bousseloub, A; Chaib, S; Debzi, N; Gamar, L; Kadiri, H; Kecili, L; Meddour, Y; Smara, M | 1 |
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| Brotchie, JM; Chiu, WH; Decher, N; Geibl, FF; Henrich, MT; Koprich, JB; Lee, B; Matschke, LA; Oertel, WH; Timmermann, L | 1 |
| Schey, KL; Wang, Z | 1 |
| Beratis, I; Fragkiadaki, S; Kontaxopoulou, D; Koros, C; Marek, K; Papadimitriou, D; Papageorgiou, SG; Papagiannakis, N; Prentakis, A; Seibyl, J; Simitsi, A; Stamelou, M; Stefanis, L; Trapali, XG | 1 |
| Jung, JH; Kim, YS; Lee, SM; Seo, JA | 1 |
| Amr, SS; Hedley-Whyte, ET; Kamakura, T; Nadol, JB; O Apos Malley, JT | 1 |
| Brandman, O; Sitron, CS | 1 |
| Batista, F; Nauman, M; Siminovitch, K; Stanley, P; Sundaram, S; Tanwar, A; Varshney, S; Wei, HX | 1 |
| Julku, UH; Kilpeläinen, T; Myöhänen, TT; Svarcbahs, R | 1 |
| Brandman, O; Giafaglione, JM; Park, JH; Sitron, CS | 1 |
| Chen, Y; Ge, X; Huang, X; Jiang, M; Li, M; Liu, L; Liu, Y; Lu, M; Song, M; Wang, F; Wang, Y; Yang, D; Yin, J; Zhang, J; Zhang, R | 1 |
| Boschin, F; Cantara, S; Capecchi, G; Castagna, MG; Kakularam, KR; Kuhn, H; Marzocchi, C; Ricci, C; Riolo, G | 1 |
| Chen, M; Diedrich, J; Kuhle, B; Liu, Z; Moresco, JJ; Pan, T; Yang, XL; Yates Iii, JR | 1 |
| Adachi, S; Inada, T; Matsuzawa, A; Natsume, T; Noguchi, T; Okuyama, T; Seki, M; Udagawa, T | 1 |
| Baek, SA; Cha, SI; Choi, JE; Choi, SH; Do Yoo, J; Do, SK; Hong, MJ; Kang, HG; Kim, CH; Kim, JH; Kim, S; Lee, J; Lee, JH; Lee, SY; Lee, WK; Lee, YH; Park, JY; Seo, H; Yoo, SS | 1 |
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| Koga, T; Tai, A | 1 |
| Benitez, JA; Bintig, W; Eickholt, BJ; Furnari, F; Larkum, ME; Ledderose, JMT; Reed, R; Roberts, AJ; Sachdev, RNS | 1 |
| Anjum Zia, M; Jahan, N; Kiran, S; Mujtaba, N; Naqvi, SAR; Sultana, B | 1 |
| Jayanthi, LD; Mannangatti, P; Ragu Varman, D; Ramamoorthy, S; Subler, MA; Windle, JJ | 1 |
| Li, R; Shi, W; Yan, Z; Yao, L | 1 |
| Cheng, Y; Guo, Y; Jiang, W; Liu, C; Qian, H; Yang, F; Yao, W; Zhao, Y | 1 |
| Ates, O; Toker, EB; Yesilbag, K | 1 |
| Gao, Y; Li, L; Li, Y; Xiu, M | 1 |
| Huang, C; Lin, D; Lu, R; Zhang, Y; Zhou, L; Zou, H | 1 |
| Birkou, M; Delegkou, GN; Episkopou, V; Fragkaki, N; Marousis, KD; Spyroulias, GA; Toro, T | 1 |
| Chen, L; Gu, J; Huang, C; Kong, Q; Lin, D; Lu, R; Wu, W | 1 |
| Ding, T; Gao, L; Ge, J; Gu, Q; Ma, X; Shen, W; Wang, H; Xue, F; Zhang, X | 1 |
| Jenness, GR; Larson, SL; Pisani, WA; Schutt, TC; Shukla, MK | 1 |
| Ahmad, H; Ahmad, N; Chen, M; Du, J; Jin, Y; Khan, A; Li, X; Ouyang, Y; Tian, Z; Yang, P; Yang, Z; Zeng, L; Zhao, X; Zheng, X | 1 |
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| Duan, Y; Lai, J; Li, L; Shao, L; Wang, J; Wang, Y; Xing, X; Yang, Z | 1 |
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| Cao, Y; Luo, Z; Ma, Y; Shan, J; Song, X; Xu, W; Zhou, J | 1 |
| Khalid, A; O'Brien-Simpson, NM; Pyreddy, S; Qazi, F; Redmond, CE; Shukla, R; Tomljenovic-Hanic, S; Verma, R | 1 |
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22 review(s) available for alanine and threonine
| Article | Year |
|---|---|
A review of biochemical studies on the genetically distinct collagens of the skeletal system.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Bone and Bones; Cartilage, Articular; Collagen; Glutamates; Homoserine; Hydroxyproline; Leucine; Peptides; Phenylalanine; Proline; Rats; Serine; Threonine; Valine | 1973 |
Utilization of D- and DL- amino acids and analogs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Histidine; Isomerism; Keto Acids; Leucine; Methionine; Nutritional Requirements; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1972 |
Altered quantitative expression of immunoglobulin allotypes in rabbits.
Topics: Alanine; Alleles; Amino Acid Sequence; Animals; Animals, Newborn; Heterozygote; Homozygote; Immune Sera; Immunoglobulin Fragments; Immunoglobulins; Immunosuppression Therapy; Isoantigens; Methionine; Rabbits; Threonine | 1974 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Biochemical substrates for the development of the matured evoked potential.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Brain; Brain Chemistry; Dopamine; Evoked Potentials; Glutamine; Norepinephrine; Rabbits; Serotonin; Tectum Mesencephali; Threonine | 1966 |
[Multiplicity and specificity in code recognition of tRNA against specific amino acid].
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography; Cystine; Escherichia coli; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Leucine; Liver; Lysine; Phenylalanine; Rabbits; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Serine; Threonine; Tyrosine; Yeasts | 1969 |
Selective cleavage and modification of peptides and proteins.
Topics: Alanine; Aspartic Acid; Chemical Phenomena; Chemistry; Chymotrypsin; Cysteine; Glutamates; Glycine; Hydrogen-Ion Concentration; Methionine; Muramidase; Oxidation-Reduction; Peptides; Phenylalanine; Proline; Proteins; Pyrrolidines; Ribonucleases; Serine; Succinates; Threonine; Tryptophan | 1970 |
Transport of amino acids and peptides in the gut and the kidney.
Topics: Adult; Alanine; Amino Acids; Animals; Biological Transport, Active; Digestive System; Glycine; Hartnup Disease; Histidine; Humans; Hydrolysis; Intestinal Absorption; Kidney; Kidney Tubules; Leucine; Lysine; Methionine; Peptides; Phenylalanine; Proteins; Rats; Serine; Threonine; Tryptophan; Valine | 1971 |
Advances in amino acid metabolism in mammals.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acid Oxidoreductases; Amino Acids; Animals; Biological Transport; Dietary Proteins; Glutamates; Glycine; Humans; Liver; Mitochondria; Organ Specificity; Ornithine; Purine Nucleotides; Serine; Threonine; Transaminases | 1981 |
[Secretion defect of kininogens and bulk flow].
Topics: Alanine; Animals; Biological Transport; Golgi Apparatus; Kininogens; Rats; Rats, Inbred BN; Threonine | 1998 |
ELAC2/HPC2 polymorphisms, prostate-specific antigen levels, and prostate cancer.
Topics: Aged; Alanine; Case-Control Studies; Genetic Predisposition to Disease; Heterozygote; Homozygote; Humans; Leucine; Linear Models; Logistic Models; Male; Middle Aged; Neoplasm Proteins; Odds Ratio; Polymorphism, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Research Design; Risk Assessment; Risk Factors; Serine; Threonine | 2003 |
Redox regulation and reaction mechanism of human cystathionine-beta-synthase: a PLP-dependent hemesensor protein.
Topics: Alanine; Allosteric Regulation; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Crystallography, X-Ray; Cystathionine beta-Synthase; DNA Mutational Analysis; Enzyme Activation; Heme; Hemeproteins; Humans; Kinetics; Models, Chemical; Models, Molecular; Models, Structural; Molecular Sequence Data; Molecular Structure; Molecular Weight; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Substrate Specificity; Threonine | 2005 |
[Fatty acid binding protein-2 (FABP2) gene polymorphism in diabetes].
Topics: Adipocytes; Alanine; Amino Acid Substitution; Carrier Proteins; Diabetes Mellitus; Fatty Acid-Binding Proteins; Fatty Acids, Nonesterified; Genetic Predisposition to Disease; Glucose Intolerance; Humans; Insulin Resistance; Lipid Peroxidation; Polymorphism, Genetic; Racial Groups; Threonine | 2005 |
The varitint-waddler mouse phenotypes and the TRPML3 ion channel mutation: cause and consequence.
Topics: Alanine; Animals; Calcium; Genetic Predisposition to Disease; Genotype; Hair Color; Hearing; Hearing Disorders; Isoleucine; Membrane Potentials; Mice; Mice, Mutant Strains; Models, Molecular; Mutation; Phenotype; Proline; Protein Conformation; Protein Structure, Tertiary; Skin Pigmentation; Threonine; Transient Receptor Potential Channels; TRPM Cation Channels | 2008 |
Ala54Thr polymorphism of fatty acid-binding protein 2 gene and fasting blood lipids: a meta-analysis.
Topics: Adolescent; Adult; Alanine; Alleles; Cholesterol, HDL; Cholesterol, LDL; Dyslipidemias; Fatty Acid-Binding Proteins; Female; Homozygote; Humans; Male; Middle Aged; Polymorphism, Genetic; Threonine | 2010 |
Alanine-to-threonine substitutions and amyloid diseases: butyrylcholinesterase as a case study.
Topics: Alanine; Amino Acid Substitution; Amyloidosis; Animals; Butyrylcholinesterase; Disease; Humans; Threonine | 2010 |
Association of the type 2 deiodinase Thr92Ala polymorphism with type 2 diabetes: case-control study and meta-analysis.
Topics: Adult; Aged; Alanine; Case-Control Studies; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Genetic Markers; Genome-Wide Association Study; Homozygote; Humans; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Male; Middle Aged; Multicenter Studies as Topic; Polymorphism, Single Nucleotide; Single-Blind Method; Threonine | 2010 |
MTHFR C677T and A1298C polymorphisms were associated with bladder cancer risk and disease progression: a meta-analysis.
Topics: Alanine; Amino Acid Substitution; Carcinoma; Case-Control Studies; Cysteine; Disease Progression; Genetic Predisposition to Disease; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Threonine; Urinary Bladder Neoplasms | 2013 |
Insights into the evolution of lanthipeptide biosynthesis.
Topics: Alanine; Amino Acids; Bacterial Proteins; Cyclization; Cysteine; Evolution, Molecular; Hydro-Lyases; Multienzyme Complexes; Peptides, Cyclic; Protein Processing, Post-Translational; Serine; Sulfides; Threonine | 2013 |
Sex-specific effect of CPB2 Ala147Thr but not Thr325Ile variants on the risk of venous thrombosis: A comprehensive meta-analysis.
Topics: Alanine; Carboxypeptidase B2; Female; Genetic Predisposition to Disease; Humans; Isoleucine; Male; Risk Factors; Sex Factors; Threonine; Venous Thrombosis | 2017 |
A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans.
Topics: Aged; Aged, 80 and over; Alanine; Alzheimer Disease; Amino Acid Substitution; Black or African American; Case-Control Studies; Dementia; Female; Gene Frequency; Humans; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Male; Middle Aged; Polymorphism, Single Nucleotide; Threonine; United States; White People | 2018 |
An update regarding the role of WNK kinases in cancer.
Topics: Alanine; Animals; Bicarbonates; Mammals; Neoplasms; Neovascularization, Pathologic; Proline; Serine; Sodium Chloride Symporters; Threonine | 2022 |
5 trial(s) available for alanine and threonine
| Article | Year |
|---|---|
Milk protein quantity and quality in low-birth-weight infants: II. Effects on selected aliphatic amino acids in plasma and urine.
Topics: Alanine; Amino Acids; Amino Acids, Essential; Aminobutyrates; Aspartic Acid; Caseins; Citrulline; Glutamates; Glutamine; Humans; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Low Birth Weight; Infant, Newborn; Milk Proteins; Proline; Threonine | 1977 |
Serum levels of excitatory amino acids, serine, glycine, histidine, threonine, taurine, alanine and arginine in treatment-resistant depression: modulation by treatment with antidepressants and prediction of clinical responsivity.
Topics: Adult; Aged; Alanine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arginine; Asparagine; Aspartic Acid; Depressive Disorder, Major; Drug Resistance; Drug Therapy, Combination; Excitatory Amino Acids; Female; Fluoxetine; Glycine; Histidine; Humans; Male; Middle Aged; Personality Inventory; Pindolol; Prognosis; Selective Serotonin Reuptake Inhibitors; Serine; Taurine; Threonine; Trazodone; Treatment Outcome | 1998 |
Proton MR spectroscopy with metabolite-nulling reveals elevated macromolecules in acute multiple sclerosis.
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Alanine; Amino Acids; Aspartic Acid; Biomarkers; Choline; Corpus Callosum; Female; Humans; Isoleucine; Leucine; Lipoma; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis; Proteins; Threonine; Valine | 2001 |
A Thr94Ala mutation in human liver fatty acid-binding protein contributes to reduced hepatic glycogenolysis and blunted elevation of plasma glucose levels in lipid-exposed subjects.
Topics: Alanine; Blood Glucose; Body Weight; Cohort Studies; Fatty Acid-Binding Proteins; Female; Genotype; Glucose Clamp Technique; Glycogenolysis; Humans; Lipids; Liver; Male; Middle Aged; Mutation; Threonine | 2007 |
Fatty acid-binding protein 2 Ala54Thr genotype is associated with insulin resistance and leptin levels changes after a high monounsaturated fat diet in obese non-diabetic patients.
Topics: Adult; Alanine; Amino Acid Substitution; Diet, High-Fat; Dietary Fats, Unsaturated; Fatty Acid-Binding Proteins; Female; Genotype; Humans; Insulin Resistance; Leptin; Male; Middle Aged; Mutation, Missense; Obesity; Polymorphism, Single Nucleotide; Threonine | 2013 |
1019 other study(ies) available for alanine and threonine
| Article | Year |
|---|---|
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2022 |
The free amino acid pool composition during growth of the culture of Xanthomonas citri (Hasse) Dowson.
Topics: Alanine; Amino Acids; Asparagine; Kinetics; Threonine; Tyrosine; Xanthomonas | 1979 |
Alkaline borohydride treatment of cartilage keratan sulfate: a comparison of two reaction conditions.
Topics: Alanine; Animals; Cattle; Chromatography, Ion Exchange; Evaluation Studies as Topic; Galactosamine; Glucosamine; Glycosaminoglycans; Keratan Sulfate; Methods; Nasal Septum; Papain; Serine; Threonine | 1975 |
Induction of nutritional mutants of Micrococcus glutamicus and their amino acid accumulation.
Topics: Alanine; Amino Acids; Biotin; Cell Count; Chromatography, Paper; Cobalt Radioisotopes; Colorimetry; Fermentation; Glutamates; Mesylates; Methionine; Micrococcus; Mutagens; Mutation; Radiation Genetics; Threonine; X-Rays | 1975 |
Formation of amino acids by cobalt-60 irradiation of hydrogen cyanide solutions.
Topics: Alanine; Amino Acids; Aspartic Acid; Cobalt Radioisotopes; Glutamates; Glycine; Hydrogen Cyanide; Hydrolysis; Serine; Threonine; Valine | 1976 |
Individual assignments of the methyl resonances in the 1H nuclear magnetic resonance spectrum of the basic pancreatic trypsin inhibitor.
Topics: Alanine; Amino Acid Sequence; Aprotinin; Chemical Phenomena; Chemistry; Magnetic Resonance Spectroscopy; Metals, Rare Earth; Methylation; Protein Conformation; Threonine | 1978 |
Alteration of free serum amino acids in voles infected with Trypanosoma brucei gambiense.
Topics: Alanine; Amino Acids; Animals; Arvicolinae; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Male; Proline; Serine; Threonine; Trypanosomiasis, African; Tryptophan; Tyrosine; Valine | 1977 |
On the biosynthesis of 5-methoxyuridine and uridine-5-oxyacetic acid in specific procaryotic transfer RNAs.
Topics: Alanine; Bacillus subtilis; Escherichia coli; Oligoribonucleotides; RNA, Transfer; S-Adenosylmethionine; Serine; Threonine; Uridine; Valine | 1978 |
Semi-synthesis of human insulin by trypsin-catalysed replacement of Ala-B30 by Thr in porcine insulin.
Topics: Alanine; Animals; Humans; Insulin; Swine; Threonine; Trypsin | 1979 |
[Free amino acids in calf embryos].
Topics: Alanine; Amino Acids; Animals; Cattle; Embryo, Mammalian; Glycine; Histidine; Isoleucine; Leucine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1979 |
Diurnal variations in plasma concentrations of tryptophan, tryosine, and other neutral amino acids: effect of dietary protein intake.
Topics: Adult; Alanine; Amino Acids; Circadian Rhythm; Dietary Proteins; Glycine; Humans; Isoleucine; Leucine; Male; Middle Aged; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1979 |
Quantitation of the beta-elimination reaction as used on glycoproteins.
Topics: Alanine; Amino Acids; Borohydrides; Butyrates; Chemistry, Organic; Galactosamine; Glucosamine; Glycoproteins; Hexosamines; Organic Chemistry Phenomena; Serine; Serum Albumin; Threonine | 1977 |
Enzymatic transfer of oligosaccharide from oligosaccharide-lipids to an Asn-Ala-Thr containing heptapeptide.
Topics: Alanine; Animals; Asparagine; Glycolipids; Guanosine Diphosphate Mannose; Kinetics; Microsomes; Oligopeptides; Oligosaccharides; Swine; Threonine; Thyroid Gland | 1978 |
Inhibition of growth and cell wall synthesis of Mycobacterium smegmatis by d-threonine.
Topics: Alanine; Cell Wall; Glycine; Mucoproteins; Muramidase; Mycobacterium; Sucrose; Threonine | 1978 |
Hemoglobin A1C separation by isoelectric focusing.
Topics: Alanine; Aminocaproic Acid; Diabetes Mellitus, Type 1; Glycine; Hemoglobin A; Histidine; Humans; Isoelectric Focusing; Proline; Threonine; Valerates | 1978 |
The variability of human lambda-chain constant regions and some relationships to V-regions sequences.
Topics: Alanine; Amino Acid Sequence; Chromatography, Gel; Chromatography, Ion Exchange; Cystine; Electrophoresis, Paper; Glutamates; Glycine; Humans; Immunoglobulin lambda-Chains; Immunoglobulin Light Chains; Isoleucine; Leucine; Peptides; Proline; Serine; Thiazoles; Threonine; Valine | 1976 |
Chemical composition and turnover of peptidoglycan in Neisseria gonorrhoeae.
Topics: Alanine; Aspartic Acid; Cell Wall; Diaminopimelic Acid; Glucosamine; Glutamates; Glycine; Muramic Acids; Neisseria gonorrhoeae; Peptidoglycan; Threonine | 1976 |
5-methoxyuridine: a new minor constituent located in the first position of the anticodon of tRNAAla, tRNAThr, and tRNAVal from Bacillus subtilis.
Topics: Alanine; Anticodon; Bacillus subtilis; Base Sequence; RNA, Bacterial; RNA, Transfer; Threonine; Uridine; Valine | 1976 |
Route of administration and portal vein amino acid concentration.
Topics: Administration, Oral; Alanine; Amino Acids; Animals; Glycine; Injections, Intravenous; Liver; Parenteral Nutrition; Portal Vein; Rats; Threonine; Tyrosine | 1976 |
Synthesis of angiotensin II antagonists by incorporating alpha-methylalanine or O-methylthreonine residues in angiotension II analogues.
Topics: Alanine; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Rabbits; Rats; Threonine | 1977 |
Turnover of transfer RNA species during development of the posterior silkgland of Bombyx mori L.
Topics: Alanine; Animals; Aspartic Acid; Bombyx; Glycine; Larva; Metamorphosis, Biological; RNA, Transfer; Sebaceous Glands; Serine; Threonine; Time Factors | 1976 |
Stereochemistry of the reaction of sheep liver threonine dehydratase. A nuclear magnetic resonance and optical rotatory dispersion study of its reaction pathway and products.
Topics: Alanine; Animals; Butyrates; Cysteine; Hydro-Lyases; Keto Acids; Liver; Magnetic Resonance Spectroscopy; Optical Rotatory Dispersion; Propionates; Serine; Sheep; Stereoisomerism; Threonine; Threonine Dehydratase | 1976 |
Multiple structural genes for the alpha chain of canine (Canis familiaris) hemoglobin.
Topics: Alanine; Amino Acid Sequence; Animals; Dogs; Genes; Globins; Hemoglobins; Threonine | 1976 |
[Aminoacid composition of the blood serum in patients with toxic goiter].
Topics: Adolescent; Adult; Alanine; Amino Acids; Female; Goiter; Humans; Hyperthyroidism; Isoleucine; Leucine; Lysine; Male; Middle Aged; Threonine; Tryptophan; Valine | 1976 |
Conditions affecting plasma amino acid patterns in chickens fed practical and purified diets.
Topics: Age Factors; Alanine; Amino Acids; Animals; Arginine; Chickens; Circadian Rhythm; Diet; Food Deprivation; Isoleucine; Lysine; Threonine; Valine | 1976 |
Amino acid composition, distribution and origin of "tuft" protein in human and bovine dental enamel.
Topics: Alanine; Amelogenesis; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Dental Enamel; Dental Enamel Proteins; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Free amino acids and amines in human dental plaque.
Topics: Alanine; Amines; Amino Acids; Aminobutyrates; Aspartic Acid; Cadaverine; Chemical Fractionation; Chromatography, Thin Layer; Dansyl Compounds; Dental Plaque; Fluorescence; Fluorometry; Glutamates; Glycine; Histamine; Humans; Ion Exchange; Lysine; Proline; Putrescine; Serine; Threonine; Valine | 1975 |
Studies on convulsants in the isolated frog spinal cord. I. Antagonism of amino acid responses.
Topics: Alanine; Amino Acids; Aminocaproates; Aminoisobutyric Acids; Animals; Asparagine; Bicuculline; Convulsants; Cystathionine; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Imidazoles; In Vitro Techniques; Isomerism; Leucine; Membrane Potentials; Nerve Endings; Neurons, Afferent; Picrotoxin; Rana pipiens; Serine; Spinal Cord; Strychnine; Taurine; Threonine; Valine | 1975 |
Isolation of a new peptide antibiotic TL-119. Studies on antibiotics from the genus Bacillus. IV.
Topics: Alanine; Animals; Anti-Bacterial Agents; Bacillus; Leucine; Mice; Peptides; Phenylalanine; Staphylococcal Infections; Staphylococcus; Threonine; Valine | 1975 |
Synthesis by conventional methods of human growth hormone peptide fragments. I.
Topics: Alanine; Asparagine; Aspartic Acid; Glutamine; Growth Hormone; Histidine; Humans; Leucine; Lysine; Optical Rotation; Peptides; Phenylalanine; Serine; Threonine; Tyrosine | 1975 |
Glycoprotein and protein antifreezes in two Alaskan fishes.
Topics: Alanine; Alaska; Animals; Blood Proteins; Chromatography, Ion Exchange; Fishes; Freezing; Glycoproteins; Seawater; Threonine | 1975 |
Mass spectrometry of fluorescamine derivatives of amino acids and peptides.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Dipeptides; Fluorescamine; Leucine; Mass Spectrometry; Molecular Conformation; Phenylalanine; Structure-Activity Relationship; Threonine | 1975 |
[Isolation and amino acid composition of two pathologically augmented proteins from psoriatic scales (author's transl)].
Topics: Alanine; Amino Acids; Electrophoresis, Disc; Galactosamine; Glycine; Humans; Leucine; Proteins; Psoriasis; Serine; Skin; Threonine | 1975 |
Developmental changes of free amino acids in bovine fetal fluids with gestational age and the interrelationships between the amino acid concentrations in the fluid compartments.
Topics: Alanine; Allantois; Amino Acids; Amniotic Fluid; Animals; Body Fluids; Cattle; Female; Fetal Blood; Fetus; Gastric Mucosa; Gestational Age; Methionine; Ornithine; Pregnancy; Serine; Stomach; Taurine; Threonine | 1975 |
[Some indices of nitrogen metabolism in patients with viral hepatitis].
Topics: Adolescent; Adult; Alanine; Ammonia; Asparagine; Chronic Disease; Cysteine; Cystinuria; Glutamates; Glycine; Hepatitis A; Humans; Isoleucine; Leucine; Methionine; Middle Aged; Nitrogen; Phenylalanine; Serine; Threonine; Urea; Valine | 1975 |
Characterization of neutral amino acid transport in a marine pseudomonad.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport, Active; Glycine; Isoleucine; Kinetics; Leucine; Mutation; Pseudomonas; Seawater; Serine; Stereoisomerism; Threonine; Valine; Water Microbiology | 1975 |
Compartmentalization of amino acids in surfactant aggregates. Partitioning between water and aqueous micellar sodium deodecanoate and between hexane and dodecylammonium propionate trapped water in hexane.
Topics: Alanine; Alkanes; Amino Acids; Arginine; Aspartic Acid; Colloids; Glutamates; Glycine; Isoleucine; Laurates; Leucine; Lysine; Micelles; Phenylalanine; Proline; Serine; Solubility; Threonine; Valine | 1975 |
[Free amino acids in the amniotic fluid and in maternal blood in advanced pregnancy].
Topics: Alanine; Amino Acids; Amniotic Fluid; Cysteine; Female; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Pregnancy Trimester, Third; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Studies on trypsin inhibitors. Part I. Synthesis of protected peptides related to sequence 1-10 of porcine pancreatic secretory trypsin inhibitor II (Kazal).
Topics: Alanine; Animals; Arginine; Cysteine; Glutamine; Peptides; Proline; Serine; Swine; Threonine; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Valine | 1976 |
Alanine and glutamine synthesis and release from skeletal muscle. II. The precursor role of amino acids in alanine and glutamine synthesis.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Glutamine; Glycine; In Vitro Techniques; Insulin; Kinetics; Leucine; Lysine; Male; Methionine; Muscles; Rats; Threonine | 1976 |
[The pattern of distribution of free amino acids in human amniotic fluid related to the duration of pregnancy. Part I: Changes in concentration in normal pregnancy (author's transl)].
Topics: Alanine; Amino Acids; Amniotic Fluid; Chromatography, Gas; Cysteine; Female; Gestational Age; Glycine; Humans; Hydroxyproline; Methionine; Ornithine; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1976 |
Serine residues responsible for tetracycline transport are on a vertical stripe including Asp-84 on one side of transmembrane helix 3 in transposon Tn10-encoded tetracycline/H+ antiporter of Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Antiporters; Aspartic Acid; Bacterial Proteins; Base Sequence; Biological Transport; Carrier Proteins; Cell Membrane; Cysteine; DNA Transposable Elements; DNA, Bacterial; Escherichia coli; Immunoblotting; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Repressor Proteins; Serine; Tetracycline; Threonine | 1992 |
Dynorphin increases extracellular levels of excitatory amino acids in the brain through a non-opioid mechanism.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Dialysis; Dynorphins; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine; Kinetics; Male; Neurotransmitter Agents; Peptide Fragments; Rats; Rats, Inbred Strains; Serine; Stereotaxic Techniques; Taurine; Threonine | 1992 |
C1 inhibitor hinge region mutations produce dysfunction by different mechanisms.
Topics: Alanine; Amino Acid Sequence; Angioedema; Animals; Base Sequence; Cell Line; Cells, Cultured; Codon; Complement C1 Inactivator Proteins; Complement C1s; Fibroblasts; Glutamates; Glutamic Acid; Heterozygote; Humans; Kallikreins; Molecular Sequence Data; Point Mutation; Protein Structure, Secondary; Recombinant Proteins; Threonine; Transfection; Valine | 1992 |
Formation of new heterocyclic amine mutagens by heating creatinine, alanine, threonine and glucose.
Topics: Alanine; Amines; Amino Acids; Chromatography, High Pressure Liquid; Cooking; Creatinine; Glucose; Heterocyclic Compounds; Hot Temperature; Magnetic Resonance Spectroscopy; Maillard Reaction; Mass Spectrometry; Meat; Mutagenicity Tests; Mutagens; Quinoxalines; Salmonella typhimurium; Threonine | 1992 |
L-threonine transport in pig jejunal brush border membrane vesicles. Functional characterization of the unique system B in the intestinal epithelium.
Topics: Alanine; Animals; Biological Transport; In Vitro Techniques; Intestinal Absorption; Jejunum; Kinetics; Lysine; Membrane Potentials; Microvilli; Phenylalanine; Proline; Sodium; Swine; Threonine | 1992 |
Serine-376 contributes to the binding of substrate by ribulose-bisphosphate carboxylase/oxygenase from Anacystis nidulans.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Cyanobacteria; Cysteine; Enzyme Activation; Kinetics; Mutagenesis, Site-Directed; Protein Binding; Ribulose-Bisphosphate Carboxylase; Serine; Substrate Specificity; Threonine | 1992 |
An alanine-to-threonine substitution in protein 4.2 cDNA is associated with a Japanese form of hereditary hemolytic anemia (protein 4.2NIPPON).
Topics: Alanine; Amino Acid Sequence; Anemia, Hemolytic; Base Sequence; Blood Proteins; Blotting, Western; Codon; Cytoskeletal Proteins; DNA; Erythrocyte Membrane; Humans; Japan; Membrane Proteins; Molecular Sequence Data; Mutation; Nucleic Acid Hybridization; Peptide Fragments; Polymerase Chain Reaction; Reticulocytes; RNA Splicing; RNA, Messenger; Threonine | 1992 |
Amino acid profiles correlate diagnostically with organ site in three kinds of malignant tumors.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Arginine; Breast Neoplasms; Carcinoma, Squamous Cell; Discriminant Analysis; Female; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Male; Middle Aged; Sex Factors; Threonine | 1992 |
L-alanine binding sites and Na+, K(+)-ATPase in cilia and other membrane fractions from olfactory rosettes of Atlantic salmon.
Topics: Alanine; Animals; Binding Sites; Cell Membrane; Cilia; Hydrogen-Ion Concentration; Mercuric Chloride; Olfactory Mucosa; Salmon; Serine; Sodium-Potassium-Exchanging ATPase; Threonine | 1991 |
Replacement of leucine-93 by alanine or threonine slows down the decay of the N and O intermediates in the photocycle of bacteriorhodopsin: implications for proton uptake and 13-cis-retinal----all-trans-retinal reisomerization.
Topics: Alanine; Amino Acid Sequence; Bacteriorhodopsins; Cloning, Molecular; Darkness; Escherichia coli; Isomerism; Kinetics; Leucine; Light; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protons; Recombinant Proteins; Retinaldehyde; Rhodopsin; Spectrophotometry; Threonine | 1991 |
Assignment of resonance in the 1H spectrum of rat brain by two-dimensional shift correlated and J-resolved NMR spectroscopy.
Topics: Alanine; Animals; Aspartic Acid; Brain Chemistry; Chromatography, Ion Exchange; Creatine; Electron Spin Resonance Spectroscopy; Female; Fourier Analysis; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Hydrogen; Inositol; Lactates; Magnetic Resonance Spectroscopy; Rats; Rats, Inbred Strains; Taurine; Threonine | 1991 |
Evidence for a structural mutation (347Ala to Thr) in a German family with 3-ketothiolase deficiency.
Topics: Acetyl-CoA C-Acyltransferase; Alanine; Amino Acid Sequence; Base Sequence; Cell Line; Child; Female; Germany; Humans; Male; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Polymerase Chain Reaction; Restriction Mapping; RNA; Threonine | 1991 |
Control of ligand specificity in cyclic nucleotide-gated channels from rod photoreceptors and olfactory epithelium.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Cattle; Cyclic AMP; Cyclic GMP; DNA Mutational Analysis; Electric Conductivity; Ion Channel Gating; Ion Channels; Ligands; Molecular Sequence Data; Photoreceptor Cells; Protein Kinases; Sequence Alignment; Serine; Smell; Threonine; Xenopus laevis | 1991 |
Serine hydroxymethyltransferase: origin of substrate specificity.
Topics: Alanine; Amino Acid Sequence; Escherichia coli; Glycine Hydroxymethyltransferase; Hydrolysis; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Substrate Specificity; Threonine | 1992 |
Crystal structure of the cytochrome P-450CAM active site mutant Thr252Ala.
Topics: Alanine; Binding Sites; Camphor 5-Monooxygenase; Crystallization; Cytochrome P-450 Enzyme System; Electron Transport; Hydrogen Bonding; Hydroxylation; Mixed Function Oxygenases; Molecular Structure; Mutagenesis, Site-Directed; Protein Conformation; Pseudomonas putida; Threonine; X-Ray Diffraction | 1991 |
Ischemic neuronal injury in the rat hippocampus following transient forebrain ischemia: evaluation using in vivo microdialysis.
Topics: Alanine; Amino Acids; Animals; Cell Survival; Dialysis; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Hippocampus; Ischemic Attack, Transient; Male; Neurons; Potassium; Rats; Rats, Inbred Strains; Taurine; Threonine | 1991 |
Aminoaciduria as a marker of acute renal transplant rejection--a patient study.
Topics: Adolescent; Alanine; Amino Acids; Child; Child, Preschool; Creatinine; Female; Glycine; Graft Rejection; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Serine; Threonine | 1991 |
Antithrombin Cambridge II, 384 Ala to Ser. Further evidence of the role of the reactive centre loop in the inhibitory function of the serpins.
Topics: Aged; Alanine; Antithrombin III; Base Sequence; Binding Sites; Exons; Heparin; Humans; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Proline; Protein Conformation; Serine; Serpins; Threonine; Thrombophlebitis; United Kingdom | 1991 |
Concentrations of amino acids in the plasma of neonatal foals with septicemia.
Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Arginine; Citrulline; Female; Glycine; Gram-Negative Bacteria; Horse Diseases; Horses; Immunoglobulin G; Isoleucine; Male; Phenylalanine; Proline; Sepsis; Threonine; Valine | 1991 |
Secondary structure and side-chain 1H and 13C resonance assignments of calmodulin in solution by heteronuclear multidimensional NMR spectroscopy.
Topics: Alanine; Amino Acid Sequence; Amino Acids, Branched-Chain; Amino Acids, Diamino; Amino Acids, Dicarboxylic; Animals; Asparagine; Binding Sites; Calcium; Calmodulin; Drosophila melanogaster; Glutamine; Glycine; Hydrogen Bonding; Leucine; Magnetic Resonance Spectroscopy; Methionine; Molecular Sequence Data; Molecular Structure; Proline; Recombinant Proteins; Serine; Solutions; Threonine | 1991 |
Antithrombin Glasgow II: alanine 382 to threonine mutation in the serpin P12 position, resulting in a substrate reaction with thrombin.
Topics: Adult; Alanine; Antithrombin III; Electrophoresis, Polyacrylamide Gel; Female; Humans; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Recurrence; Serpins; Threonine; Thrombin; Thrombosis | 1991 |
Albumin Redhill (-1 Arg, 320 Ala----Thr): a glycoprotein variant of human serum albumin whose precursor has an aberrant signal peptidase cleavage site.
Topics: Alanine; Amino Acid Sequence; Arginine; Base Sequence; Endopeptidases; Genes; Genetic Variation; Humans; Membrane Proteins; Molecular Sequence Data; Oligonucleotide Probes; Peptide Fragments; Peptide Mapping; Polymerase Chain Reaction; Prealbumin; Sequence Homology, Nucleic Acid; Serine Endopeptidases; Serum Albumin; Serum Albumin, Human; Threonine; Trypsin | 1990 |
Two-dimensional NMR studies of staphylococcal nuclease. 1. Sequence-specific assignments of hydrogen-1 signals and solution structure of the nuclease H124L-thymidine 3',5'-bisphosphate-Ca2+ ternary complex.
Topics: Alanine; Amino Acid Sequence; Calcium; Glycine; Isoleucine; Magnetic Resonance Spectroscopy; Micrococcal Nuclease; Molecular Sequence Data; Molecular Structure; Protein Conformation; Serine; Solutions; Threonine; Thymine Nucleotides; Valine | 1990 |
Lipoprotein lipaseBethesda: a single amino acid substitution (Ala-176----Thr) leads to abnormal heparin binding and loss of enzymic activity.
Topics: Adult; Alanine; Amino Acid Sequence; Base Sequence; Chromatography, Affinity; DNA; Heparin; Humans; Leukocytes; Lipoprotein Lipase; Macrophages; Male; Molecular Sequence Data; Mutation; Plasmids; Polymerase Chain Reaction; Protein Binding; Reference Values; Restriction Mapping; Threonine; Transfection | 1990 |
Linear dichroism studies of tryptophanase and its quasisubstrate complexes oriented in polyacrylamide gel.
Topics: Alanine; Binding Sites; Escherichia coli; Ligands; Oxindoles; Protein Binding; Protein Conformation; Serine; Spectrum Analysis; Threonine; Tryptophanase | 1990 |
Familial amyloid polyneuropathy: alanine-for-threonine substitution in the transthyretin (prealbumin) molecule.
Topics: Adult; Aged; Alanine; Amyloidosis; Blotting, Southern; DNA; Female; Humans; Isoelectric Focusing; Male; Myocardium; Nervous System Diseases; Pedigree; Prealbumin; Retinol-Binding Proteins; Threonine | 1990 |
Proton NMR studies of apo-neocarzinostatin from Streptomyces carzinostaticus. Sequence-specific assignment and secondary structure.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Antibiotics, Antineoplastic; Glycine; Leucine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Protein Conformation; Solutions; Streptomyces; Threonine; Valine; Zinostatin | 1990 |
Molecular and biochemical characterization of the Dio-9-resistant pma1-1 mutation of the H(+)-ATPase from Saccharomyces cerevisiae.
Topics: Alanine; Cell Membrane; DNA, Fungal; Genomic Library; Hydrogen-Ion Concentration; Kinetics; Mutation; Proton-Translocating ATPases; Saccharomyces cerevisiae; Threonine | 1990 |
One amino acid change produces a high affinity cGMP-binding site in cAMP-dependent protein kinase.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cattle; Cyclic AMP; Cyclic GMP; Kinetics; Macromolecular Substances; Male; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Protein Kinases; Testis; Threonine | 1990 |
Phosphorylation of the epidermal growth factor receptor at threonine 654 inhibits ligand-induced internalization and down-regulation.
Topics: Alanine; Animals; Cell Line; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Ligands; Mice; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Threonine; Transfection | 1990 |
Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation.
Topics: Alanine; Base Sequence; Camphor 5-Monooxygenase; Cloning, Molecular; Cytochrome P-450 Enzyme System; Escherichia coli; Genes, Bacterial; Kinetics; Mixed Function Oxygenases; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Oxygen Consumption; Plasmids; Pseudomonas; Serine; Threonine; Valine | 1989 |
Function of threonine-55 in the carbamoyl phosphate binding site of Escherichia coli aspartate transcarbamoylase.
Topics: Alanine; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Carbamyl Phosphate; Escherichia coli; Kinetics; Molecular Structure; Mutation; Phosphonoacetic Acid; Protein Conformation; Threonine | 1989 |
Mechanism of phosphorylation of the epidermal growth factor receptor at threonine 669.
Topics: Alanine; Animals; Cell Line; Cells, Cultured; ErbB Receptors; Humans; Mutation; Peptide Mapping; Phosphopeptides; Phosphoprotein Phosphatases; Phosphorylation; Plasmids; Protein Kinases; Protein Serine-Threonine Kinases; Submandibular Gland; Threonine | 1989 |
Predicted structures of the cGMP binding domains of the cGMP-dependent protein kinase: a key alanine/threonine difference in evolutionary divergence of cAMP and cGMP binding sites.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Biological Evolution; Cyclic AMP; Cyclic GMP; Humans; Models, Chemical; Molecular Sequence Data; Molecular Structure; Protein Kinases; Sequence Homology, Nucleic Acid; Threonine | 1989 |
Studies of the regulatory mechanism of Ca2+/calmodulin-dependent protein kinase II. Mutation of threonine 286 to alanine and aspartate.
Topics: Alanine; Animals; Aspartic Acid; Base Sequence; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cloning, Molecular; DNA; Macromolecular Substances; Mice; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Plasmids; Protein Biosynthesis; Protein Kinases; Rabbits; Rats; Reticulocytes; Threonine; Transcription, Genetic | 1989 |
Effect of impact trauma on neurotransmitter and nonneurotransmitter amino acids in rat spinal cord.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kinetics; Laminectomy; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Serine; Spinal Cord; Spinal Cord Injuries; Taurine; Threonine | 1989 |
Splanchnic substrate balance in malnourished patients during parenteral nutrition.
Topics: Adipose Tissue; Alanine; Amino Acids, Branched-Chain; Cystine; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycine; Humans; Lipids; Liver; Male; Mesentery; Nitrogen; Parenteral Nutrition; Parenteral Nutrition, Total; Protein Biosynthesis; Protein-Energy Malnutrition; Serine; Splanchnic Circulation; Threonine; Tyrosine | 1985 |
Effect of protein intake on amino acid catabolism and gluconeogenesis by isolated hepatocytes from the cat (Felis domestica).
Topics: Alanine; Amino Acids; Animals; Cats; Dietary Proteins; Gluconeogenesis; Glutamine; Kinetics; Liver; Pyruvates; Pyruvic Acid; Threonine; Tryptophan Oxygenase; Tyrosine Transaminase; Urea | 1985 |
Phosphorylation of synthetic peptides by skeletal muscle myosin light chain kinases.
Topics: Alanine; Amino Acid Sequence; Animals; Chickens; Glutamates; Glutamic Acid; Kinetics; Myosin-Light-Chain Kinase; Oligopeptides; Protein Kinases; Rabbits; Threonine | 1986 |
Glutamic acid as a putative transmitter of the interhemispheric corticocortical connections in the rat.
Topics: Alanine; Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Male; Rats; Rats, Inbred Strains; Serine; Threonine | 1986 |
Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms.
Topics: Alanine; Cell Line; DNA; Epidermal Growth Factor; ErbB Receptors; Humans; Methionine; Mutation; Phosphorylation; Protein Conformation; Protein Kinase C; Receptors, Cell Surface; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Threonine; Transcription, Genetic | 1986 |
[Various routes of L-tryptophan transport in the small intestine of the chick].
Topics: Alanine; Animals; Chickens; In Vitro Techniques; Intestinal Absorption; Kinetics; Sodium; Threonine; Tryptophan; Valine | 1986 |
Characterization of carrier-mediated transport systems for small neutral amino acids in human fibroblast lysosomes.
Topics: Alanine; Amino Acids; Biological Transport, Active; Fibroblasts; Humans; Kinetics; Lysosomes; Mathematics; Osmolar Concentration; Proline; Serine; Sodium Chloride; Threonine | 1987 |
[Abnormal plasminogen and thrombosis].
Topics: Adult; Alanine; Amino Acid Sequence; Fibrinolysis; Humans; Isoelectric Focusing; Male; Plasminogen; Threonine; Thrombosis | 1987 |
Molecular cloning of a human apoC-III variant: Thr 74----Ala 74 mutation prevents O-glycosylation.
Topics: Alanine; Amino Acid Sequence; Apolipoprotein C-III; Apolipoproteins C; Base Sequence; Cloning, Molecular; DNA; Glycosylation; Humans; Lipoproteins, VLDL; Molecular Sequence Data; Mutation; Threonine | 1987 |
Characterization of a novel L-serine transport system in Escherichia coli.
Topics: Alanine; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane; Culture Media; Escherichia coli; Glycine; Isoleucine; Kinetics; Potassium Cyanide; Serine; Threonine; Valine | 1988 |
Echinococcus granulosus (Cestoda): uptake of L-amino acids by secondary hydatid cysts.
Topics: Absorption; Alanine; Amino Acids; Animals; Biological Transport; Cycloleucine; Echinococcosis; Echinococcus; Kinetics; Mathematics; Mice; Mice, Inbred BALB C; Proline; Threonine | 1988 |
Sodium-dependent transport of neutral amino acids by whole cells and membrane vesicles of Streptococcus bovis, a ruminal bacterium.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Cell Membrane; Glucose; Membrane Potentials; Rumen; Serine; Sodium; Streptococcus; Threonine | 1988 |
Mutant Trp repressors with new DNA-binding specificities.
Topics: Alanine; Amino Acid Sequence; Apoproteins; Bacterial Proteins; Base Sequence; Binding Sites; Codon; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Glutamine; Isoleucine; Lysine; Mutation; Operator Regions, Genetic; Protein Conformation; Repressor Proteins; Threonine; Transcription Factors | 1988 |
Effects of glycine and other inhibitory amino acid neurotransmitters on strychnine convulsive threshold in mice.
Topics: Alanine; Animals; beta-Alanine; Diazepam; Dose-Response Relationship, Drug; Glycine; Male; Mice; Mice, Inbred ICR; Seizures; Strychnine; Threonine | 1985 |
Avoidance of GABA-containing diets by olfactory bulbectomized rats.
Topics: Alanine; Animals; Diet; Food Preferences; gamma-Aminobutyric Acid; Male; Odorants; Olfactory Bulb; Rats; Rats, Inbred Strains; Threonine | 1985 |
A new Na+-independent transport system for dipolar amino acids apparently corresponding to systems persisting after erythrocyte maturation in some mammalian genotypes.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Columbidae; Cysteine; Erythrocyte Aging; Erythrocytes; Horses; Kinetics; Serine; Sheep; Sodium; Species Specificity; Threonine | 1985 |
Antigenic and C-substance activities of related glycopeptides from fungal, parasitic and vegetable sources.
Topics: Alanine; Antigen-Antibody Reactions; Antigens; Ascaris; Aspartic Acid; Aspergillus; C-Reactive Protein; Cross Reactions; Epidermophyton; Epitopes; Galactose; Glutamates; Glycopeptides; Mannose; Peptides; Plants; Polysaccharides, Bacterial; Serine; Skin Tests; Threonine; Trichophyton | 1971 |
Studies on the enzymes involved in the biosynthesis of cyclo-tris (N-2,3-dihydroxybenzoyl-L-seryl) in Escherichia coli: kinetic properties of the L-serine-activating enzyme.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Anti-Bacterial Agents; Drug Stability; Enzyme Induction; Escherichia coli; Ethylmaleimide; Glycine; Gramicidin; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Phosphates; Phosphorus Radioisotopes; Proline; Serine; Threonine; Time Factors; Tritium; Tyrosine | 1973 |
[Properties of amino acid pools of actinomycin-producing actinomycetes].
Topics: Actinomycetales; Alanine; Amino Acids; Chloramphenicol; Culture Media; Dactinomycin; Glycine; Isoleucine; Leucine; Peptides; Phenylalanine; Threonine; Thyroxine; Valine | 1973 |
Accumulation of neutral amino acids by Streptococcus faecalis. Energy coupling by a proton-motive force.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Biological Transport, Active; Carbon Radioisotopes; Carboxylic Acids; Cycloserine; Dicyclohexylcarbodiimide; Energy Metabolism; Enterococcus faecalis; Glycine; Glycolysis; Hydrogen-Ion Concentration; Kinetics; Membrane Potentials; Models, Biological; Mutation; Polycyclic Compounds; Potassium; Serine; Sodium; Threonine; Time Factors; Valinomycin | 1973 |
Studies on the elimination reaction of D-amino acid oxidase with -amino- -chlorobutyrate. Further evidence for abstraction of substrate -hydrogen as a proton.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Apoproteins; Catalysis; Chlorine; D-Amino-Acid Oxidase; Deuterium; Hydrogen; Isomerism; Keto Acids; Kidney; Kinetics; Osmolar Concentration; Oxidation-Reduction; Oxygen Consumption; Protons; Serine; Spectrophotometry; Swine; Temperature; Threonine; Tritium | 1973 |
Interconversion of glycine and serine in a synaptosome fraction isolated from the spinal cord, medulla oblongata, telencephalon, and cerebellum of the rat.
Topics: Alanine; Animals; Aspartic Acid; Carbon Radioisotopes; Cerebellum; Female; Glutamates; Glutamine; Glycine; In Vitro Techniques; Medulla Oblongata; Neurotransmitter Agents; Rats; Serine; Spinal Cord; Synaptosomes; Telencephalon; Threonine | 1973 |
Light-dependent synthesis of glutamate in Rhodospirillum rubrum. Physiological evidence for ammonia assimilation via the glutamine synthetase and glutamine: 2-oxoglutarate amino-transferase system.
Topics: Alanine; Ammonia; Aspartic Acid; Carbon Dioxide; Carbon Radioisotopes; Darkness; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Light; Rhodospirillum rubrum; Threonine; Transaminases | 1974 |
The effect of changes in external salinity on the non-protein nitrogenous constituents of parietal muscle from Agonus cataphractus.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Body Water; Ethionine; Fishes; Glutamates; Glutamine; Glycine; Lysine; Methionine; Muscles; Nitrogen; Osmolar Concentration; Potassium; Seawater; Serine; Sodium; Sodium Chloride; Taurine; Threonine | 1974 |
[Relation between gamma-aminobutyric acid and tyrosine metabolism and changes in the brain and liver amino acid content in intact and adrenalectomized rats].
Topics: Adrenal Glands; Adrenalectomy; Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine; Liver; Lysine; Male; Rats; Serine; Stimulation, Chemical; Threonine; Tyrosine | 1972 |
Comparison of the amino acid sequences of the variable regions of light chains derived from two homogeneous rabbit anti-pneumococcal antibodies.
Topics: Aconitic Acid; Alanine; Amino Acid Sequence; Amino Acids; Animals; Antibodies, Bacterial; Asparagine; Aspartic Acid; Autoanalysis; Chromatography, Gel; Electrophoresis, Paper; Glutamates; Glycine; Hydrolysis; Immunoglobulin Fragments; Rabbits; Serine; Streptococcus pneumoniae; Threonine; Tyrosine; Valine | 1974 |
A blocked N-terminal residue in the light chain of rabbit immunoglobulin G.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Chromatography, Paper; Electrophoresis; gamma-Globulins; Glutamates; Glycine; Hydrogen-Ion Concentration; Leucine; Peptide Hydrolases; Rabbits; Serine; Threonine; Valine | 1968 |
Argininosuccinic aciduria in hereditary hair diseases.
Topics: Adolescent; Adult; Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Chromatography, Paper; Cystinuria; Female; Glutamates; Glutamine; Glycine; Hair; Histidine; Humans; Infant; Lysine; Male; Middle Aged; Serine; Skin Diseases; Threonine; Tyrosine; Valine | 1968 |
Fasting serum-aminoacid patterns in kwashiorkor and after administration of different levels of protein.
Topics: Adaptation, Physiological; Alanine; Amino Acids; Child; Diet Therapy; Dietary Proteins; Glycine; Growth; Humans; Kwashiorkor; Serum Albumin; Threonine | 1970 |
NH2-terminal amino acid distribution and amino acid composition of Streptococcus faecalis R soluble and ribosomal proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aspartic Acid; Autoanalysis; Bacterial Proteins; Cell-Free System; Culture Media; Dinitrophenols; Enterococcus faecalis; Folic Acid; Glutamates; Glycine; Methionine; Ribosomes; Serine; Solubility; Threonine | 1973 |
Aminoacyl transfer ribonucleic acid synthesis in toluene-treated liver cells.
Topics: Adenosine Triphosphate; Alanine; Amino Acyl-tRNA Synthetases; Animals; Arginine; Carbon Radioisotopes; Edetic Acid; Escherichia coli; In Vitro Techniques; Kinetics; Liver; Lysine; Magnesium; Male; Mercaptoethanol; Perfusion; Rats; RNA, Bacterial; RNA, Transfer; Threonine; Time Factors; Toluene; Ultracentrifugation | 1974 |
[Influence of changes in urinary pH on the excretion of amino acids from the isolated perfused rat kidney].
Topics: Alanine; Amino Acids; Animals; Arginine; Diffusion; Glycine; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Leucine; Lysine; Perfusion; Rats; Serine; Threonine; Tyrosine; Urine; Valine | 1967 |
Elimination and sulfite addition as a means of localization and identification of substituted seryl and threonyl residues in proteins and proteoglycans.
Topics: Alanine; Alkylation; Aminobutyrates; Animals; Binding Sites; Cartilage; Caseins; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Ion Exchange; Glucagon; Glycoproteins; Glycosaminoglycans; Mucins; Optical Rotatory Dispersion; Oxidation-Reduction; Phosphoproteins; Proteins; Serine; Submandibular Gland; Sulfites; Sulfones; Sulfonic Acids; Sulfur Isotopes; Swine; Threonine; Trypsin | 1972 |
Hepatic blood flow changes following intravenous infusion of various single amino acids in dogs. 3.
Topics: Alanine; Amino Acids; Animals; Arginine; Cysteine; Dogs; Electromagnetic Phenomena; Hepatic Artery; Hepatic Veins; Injections, Intravenous; Liver; Liver Circulation; Lysine; Phenylalanine; Portal System; Rheology; Stimulation, Chemical; Threonine; Tryptophan | 1974 |
Structure of amino acyl oligonucleotides from T-1 ribonuclease digests of soluble ribonucleic acid charged with serine, glycine, threonine, and alanine.
Topics: Alanine; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Glycine; Phosphoric Monoester Hydrolases; Polynucleotides; Ribonucleases; RNA, Transfer; Serine; Spectrophotometry; Threonine; Venoms | 1966 |
Primary structure of insoluble tendon collagen. II. N- and C-terminal positional analysis of collagenolytic breakdown products of trypsin-pretreated collagen.
Topics: Achilles Tendon; Alanine; Amino Acids; Animals; Arginine; Cattle; Collagen; Glycine; Hydroxyproline; Isoleucine; Leucine; Methionine; Methods; Microbial Collagenase; Phenylalanine; Proline; Threonine; Trypsin; Tyrosine | 1968 |
The divergence in reactivity of aminoacyl transfer ribonucleic acid synthetases of Escherichia coli with hydroxylamine.
Topics: Alanine; Amino Acids; Carbon Isotopes; Chromatography, Ion Exchange; Cysteine; Escherichia coli; Glutamates; Glycine; Hydroxylamines; Isoleucine; Kinetics; Leucine; Ligases; Lysine; Methionine; Periodic Acid; Phenylalanine; RNA, Bacterial; RNA, Transfer; Threonine; Tryptophan; Tyrosine | 1968 |
Specificity of the valyl ribonucleic acid synthetase from Escherichia coli in the binding of valine analogues.
Topics: Adenosine Triphosphate; Alanine; Amides; Amines; Amino Acids; Amino Alcohols; Aminobutyrates; Chemical Phenomena; Chemistry; Diphosphates; Escherichia coli; Esters; Glycine; Isoleucine; Kinetics; Leucine; Ligases; Peptides; Phosphorus Isotopes; Protein Binding; RNA, Transfer; Stereoisomerism; Threonine; Valine | 1970 |
Glycopeptides from silk fibroin of Bombyx mori.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Bombyx; Boron Compounds; Chromatography, Gel; Chromatography, Ion Exchange; Fibroins; Glucosamine; Glycine; Glycopeptides; Hydrolysis; Mannose; Molecular Weight; Oxidation-Reduction; Peptide Hydrolases; Peptides; Periodic Acid; Serine; Thiocyanates; Threonine; Trypsin | 1971 |
On the kinetics of poliovirus-specific protein and RNA synthesis in poliovirus-infected cells.
Topics: Alanine; Animals; Cell Line; Isotope Labeling; Kinetics; Macaca; Palatine Tonsil; Phenylalanine; Poliovirus; RNA, Viral; Threonine; Time Factors; Tritium; Uridine; Viral Proteins | 1973 |
Ultraviolet photobleaching of free radicals created in -irradiated amino acids.
Topics: Adipates; Alanine; Amides; Amino Acids; Electron Spin Resonance Spectroscopy; Free Radicals; Glycine; Leucine; Malonates; Radiation Effects; Threonine; Ultraviolet Rays | 1973 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Biosynthesis of valinomycin.
Topics: Adenosine Triphosphate; Alanine; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Thin Layer; Diphosphates; Electrophoresis, Paper; Hydrogen-Ion Concentration; Lactates; Phosphorus Radioisotopes; Streptomyces; Threonine; Valerates; Valine; Valinomycin | 1974 |
Amino acid sequence of an alkaline proteinase inhibitor (Streptomyces subtilisin inhibitor) from Streptomyces albogriseolus S-3253.
Topics: Alanine; Amino Acid Sequence; Chymotrypsin; Cyanogen Bromide; Leucine; Methylation; Microbial Collagenase; Proline; Streptomyces; Subtilisins; Thermolysin; Threonine; Trypsin; Trypsin Inhibitors | 1974 |
[Further studies on amino acid sequence of proteins in tobacco mosaic virus].
Topics: Alanine; Amino Acid Sequence; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis; Glutamates; Leucine; Peptides; Proline; Threonine; Tobacco Mosaic Virus; Valine; Viral Proteins | 1965 |
Regulation of aspartate family amino acid biosynthesis in Brevibacterium flavum. I. Inhibition by amino acids of the enzymes in threonine biosynthesis.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acids; Aspartate-Semialdehyde Dehydrogenase; Aspartic Acid; Brevibacterium; Cysteine; Glutathione; Isoleucine; Lyases; Lysine; Methionine; Phosphotransferases; Serine; Temperature; Threonine | 1968 |
Inorganic nitrogen assimilation in yeasts: alteration in enzyme activities associated with changes in cultural conditions and growth phase.
Topics: Alanine; Alanine Transaminase; Amino Acid Oxidoreductases; Amino Acids; Ammonium Sulfate; Aspartate Aminotransferases; Aspartic Acid; Cell-Free System; Culture Media; Electrophoresis, Disc; Genetics, Microbial; Glucose; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Hydro-Lyases; Hydrogen-Ion Concentration; Lyases; Mutation; NAD; NADP; Nitrogen; Saccharomyces; Saccharomyces cerevisiae; Spectrophotometry; Threonine; Transaminases | 1972 |
Absorption of some amino acids by the haemoflagellate, Trypanosoma gambiense.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Transport; Carbon Isotopes; Cysteine; Glutamates; Glycine; Iodoacetates; Kinetics; Leucine; Lysine; Ornithine; Rats; Serine; Threonine; Trypanosoma brucei gambiense | 1972 |
Enzymic oxidation of some resistant D-amino acids.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Cattle; D-Amino-Acid Oxidase; Glutamates; Indicators and Reagents; Kidney; Liver; Lysine; Methionine; Methods; Oxidation-Reduction; Serine; Swine; Threonine; Time Factors | 1972 |
Amino acid oxidase in leukocytes: evidence against a major role in phagocytosis.
Topics: Alanine; Amino Acid Oxidoreductases; Ascorbic Acid; Carbon Dioxide; Carbon Isotopes; D-Amino-Acid Oxidase; Glucose; Hexosephosphates; Humans; Hydrogen Peroxide; Leukocytes; Neutrophils; Oxygen Consumption; Phagocytosis; Threonine | 1972 |
Lipolytic and hypoglycemic compounds obtained from cystoseira barbata J. Ag.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Blood Glucose; Chromatography, Gel; Chromatography, Paper; Eukaryota; Glutamine; Histidine; Leucine; Lipid Metabolism; Lysine; Methionine; Peptide Fragments; Rabbits; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Composition of the rhodopsin-core obtained by proteolysis of retinal rod outer segments with papain, and its regenerability after photobleaching.
Topics: Alanine; Animals; Arginine; Carbohydrates; Cattle; Chromatography, Thin Layer; Electrophoresis; Glutamates; Glycine; Histidine; Leucine; Light; Lysine; Papain; Photoreceptor Cells; Retinal Pigments; Retinaldehyde; Rhodopsin; Threonine; Tryptophan; Tyrosine | 1974 |
The mycoside capsule of Mycobacterium Avium 357.
Topics: Alanine; Cell Membrane; Chromatography, Thin Layer; Glycolipids; Hexoses; Leucine; Microscopy, Electron; Mycobacterium; Phenylalanine; Threonine; Valine | 1974 |
Plasma concentrations of tryptophan and other amino acids in manic-depressive patients.
Topics: Alanine; Arginine; Aspartic Acid; Bipolar Disorder; Emotions; Glutamates; Glycine; Humans; Isoleucine; Leucine; Methionine; Psychology; Serine; Threonine; Tryptophan; Tyrosine | 1974 |
[Amino acid levels in the blood serum of patients with chronic colitis].
Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Betaine; Chronic Disease; Citrulline; Colitis; Glutamates; Glutamine; Glycine; Histidine; Humans; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tryptophan; Tyrosine; Urea | 1974 |
[Biochemical stigmas of human skin surface in old age (author's transl)].
Topics: Adult; Aged; Aging; Alanine; Amino Acids; Ammonia; Citrulline; Glutamates; Glycine; Histidine; Humans; Lactates; Pyrrolidonecarboxylic Acid; Skin; Surface Properties; Sweating; Threonine; Urea; Valine | 1974 |
Analogues of human calcitonin. I. Influence of modifications in amino acid positions 29 and 31 on hypocalcaemic activity in the rat.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Calcitonin; Calcium; Dose-Response Relationship, Drug; Female; Hypocalcemia; Photometry; Rats; Regression Analysis; Serine; Structure-Activity Relationship; Threonine; Time Factors; Valine | 1974 |
Kinetic studies on the alkali-catalyzed hydrolysis and epimerization of model alkyl and hydroxyalkyl di- and tripeptides.
Topics: Alanine; Alcohols; Alkanes; Borates; Chemical Phenomena; Chemistry; Dipeptides; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Leucine; Oligopeptides; Optical Rotation; Phosphates; Serine; Stereoisomerism; Threonine | 1974 |
Free amino acid levels in the boll weevil (Coleoptera: Curculionidae): the effect of five different diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography, Gas; Coleoptera; Diet; Dietary Proteins; Glutamates; Glycine; Gossypium; Histidine; Isoleucine; Leucine; Male; Mass Spectrometry; Methionine; Phenylalanine; Proline; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
[Free amino acids in the 24 h urine of healthy children (author's transl)].
Topics: Adolescent; Age Factors; Alanine; Amino Acids; Aminobutyrates; Carnosine; Child; Chromatography, Ion Exchange; Citrulline; Female; Glycine; Histidine; Humans; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Serine; Sex Factors; Threonine; Tyrosine; Valine | 1974 |
Free amino acids in the haemocytes and plasma of the larva of Calliphora vicina.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Blood Cells; Blood Coagulation; Diptera; Glutamates; Glutamine; Glycine; Hemolymph; Histidine; Isoleucine; Larva; Leucine; Lysine; Methionine; Phenylalanine; Plasma; Proline; Serine; Taurine; Threonine; Tyrosine; Valine | 1974 |
Syntheses of further analogues of norphalloin. Gly1-, L-val1- and D-Abu2-norphalloin and (beta-trideutero)-Ala5- norphalloin.
Topics: Alanine; Aminobutyrates; Anhydrides; Animals; Chromatography, Thin Layer; Cyclization; Deuterium; Lethal Dose 50; Mice; Mycotoxins; Oligopeptides; Peptides, Cyclic; Phalloidine; Polarography; Temperature; Threonine; Valine | 1974 |
Nitrogen components reaching the omasum and abomasum of lambs fed two nitrogen levels.
Topics: Abomasum; Alanine; Amino Acids; Amino Acids, Essential; Animal Feed; Animals; Glycine max; Male; Nitrogen; Omasum; Proline; Sheep; Threonine; Valine | 1974 |
Prebiotic synthesis of hydrophobic and protein amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Ammonia; Aspartic Acid; Autoanalysis; Chromatography, Gas; Glutamates; Glycine; Isoleucine; Leucine; Mass Spectrometry; Methane; Nitrogen; Proline; Serine; Threonine; Valine; Water | 1972 |
Multiplicity of the hemoglobin alpha chains in dogs and variations among related species.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Dogs; Female; Hemoglobins; Male; Peptide Fragments; Raccoons; Species Specificity; Threonine; Trypsin | 1974 |
Rat-proinsulin C-peptides. Amino-acid sequences.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Autoanalysis; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Electrophoresis, Paper; Glutamine; Glycine; Papain; Pepsin A; Peptides; Proinsulin; Proline; Rats; Threonine; Trypsin | 1972 |
Biosynthesis of melittin, a toxic peptide from bee venom. Amino-acid sequence of the precursor.
Topics: Alanine; Amides; Amino Acid Sequence; Animals; Asparagine; Bees; Carbon Isotopes; Cathepsins; Chromatography, Paper; Electrophoresis, Paper; Exocrine Glands; Glutamates; Glutamine; Glycine; Hydrolysis; Pepsin A; Peptides; Proline; Protein Precursors; Threonine; Tritium; Trypsin; Venoms | 1973 |
The nature of the electron-transparent zone that surrounds Mycobacterium lepraemurium inside host cells.
Topics: Alanine; Animals; Cell Wall; Freeze Etching; Glycolipids; Leucine; Liver; Mice; Microscopy, Electron; Mycobacterium Infections; Mycobacterium lepraemurium; Phenylalanine; Spleen; Threonine; Valine | 1973 |
Transport systems for alanine, serine, and glycine in Escherichia coli K-12.
Topics: Alanine; Autoradiography; Biological Transport, Active; Chromosome Mapping; Escherichia coli; Glycine; Leucine; Mutation; Serine; Stereoisomerism; Threonine; Transduction, Genetic | 1973 |
Multiplicity of leucine transport systems in Escherichia coli K-12.
Topics: Alanine; Bacterial Proteins; Biological Transport, Active; Chromatography, DEAE-Cellulose; Escherichia coli; Isoleucine; Leucine; Mutation; Nitrosoguanidines; Osmosis; Protein Binding; Serine; Stereoisomerism; Threonine; Transduction, Genetic; Valine | 1973 |
Multiplicity of isoleucine, leucine, and valine transport systems in Escherichia coli K-12.
Topics: Alanine; Amino Acids; Biological Transport, Active; Carbon Radioisotopes; Escherichia coli; Isoleucine; Leucine; Methionine; Mutation; Threonine; Valine | 1974 |
Mutations affecting the different transport systems for isoleucine, leucine, and valine in Escherichia coli K-12.
Topics: Alanine; Amino Acids; Bacterial Proteins; Biological Transport, Active; Chromosome Mapping; Escherichia coli; Genes; Isoleucine; Leucine; Methionine; Mutagens; Mutation; Nitrosoguanidines; Threonine; Transduction, Genetic; Ultraviolet Rays; Valine | 1974 |
Regulation of biodegradative threonine deaminase. 3. Effects of beta substituents of substrate on absorption spectrum and circular dichroism of the enzyme-bound pyridoxal phosphate.
Topics: Alanine; Binding Sites; Chlorine; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Circular Dichroism; Escherichia coli; Hydro-Lyases; Hydroxylation; Kinetics; Molecular Conformation; Protein Binding; Pyridoxal Phosphate; Schiff Bases; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Stereoisomerism; Structure-Activity Relationship; Threonine; Time Factors; Valine | 1974 |
Transport of biosynthetic intermediates: regulation of homoserine and threonine uptake in Escherichia coli.
Topics: Alanine; Amino Acids; Bacterial Proteins; Biological Transport, Active; Carbon Radioisotopes; Chloramphenicol; Depression, Chemical; Escherichia coli; Homoserine; Isoleucine; Leucine; Methionine; Threonine; Valine | 1974 |
Persisting circadian oscillations in enzyme activity in non-dividing cultures of Euglena.
Topics: Acid Phosphatase; Alanine; Alkaline Phosphatase; Amino Acid Oxidoreductases; Aminohydrolases; Cell Division; Circadian Rhythm; Darkness; Euglena gracilis; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; Kinetics; L-Lactate Dehydrogenase; Light; Serine; Threonine | 1972 |
[Amino acids in parenteral feeding].
Topics: Alanine; Amino Acids; Arginine; Histidine; Homeostasis; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Nutrition Disorders; Parenteral Nutrition; Phenylalanine; Proline; Protein Conformation; Protein-Energy Malnutrition; Proteins; Threonine; Tryptophan; Valine | 1972 |
The tryptic peptides and terminal sequences of the protein from the cowpea strain of tobacco mosaic virus.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Arginine; Autoanalysis; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Electrophoresis, Paper; Hydrolysis; Peptides; Plant Diseases; Plants, Edible; Protein Denaturation; Threonine; Tobacco Mosaic Virus; Trypsin; Tyrosine; Viral Proteins | 1972 |
Amino acid metabolism in chameleon liver.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Citrulline; Female; Glutamates; Glutamine; Glycine; Histidine; Keto Acids; Liver; Lizards; Lysine; Male; Methionine; Ornithine; Phenylalanine; Pyruvates; Serine; Threonine; Tryptophan | 1972 |
Amino acid compositions of all the tryptic peptides from the and polypeptide chains of adult hemoglobin of the slow loris (Nycticebus coucang). Biochemical studies on hemoglobins and myoglobins. X.
Topics: Alanine; Amino Acids; Animals; Arginine; Chromatography; Chromatography, Paper; Glutamine; Hemoglobins; Histidine; Isoleucine; Leucine; Lysine; Methionine; Myoglobin; Peptides; Phenylalanine; Primates; Serine; Threonine; Trypsin; Tyrosine; Valine | 1972 |
Studies on protamines. XVI. The complete amino acid sequence of clupeine YII.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Chromatography; Fishes; Male; Proline; Protamines; Serine; Spermatozoa; Threonine; Valine | 1972 |
Studies on protamines. XVII. The complete amino acid sequence of clupeine YI.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Cell Nucleus; Chromatography; Fishes; Glycine; Isoleucine; Male; Proline; Protamines; Serine; Spermatozoa; Threonine | 1972 |
Polymerization of amino acids under primitive earth conditions.
Topics: Alanine; Amino Acids; Ammonia; Aspartic Acid; Autoradiography; Biological Evolution; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Ion Exchange; Electricity; Electrophoresis, Paper; Glutamates; Glycine; Hydrolysis; Leucyl Aminopeptidase; Mass Spectrometry; Methane; Peptides; Threonine; Water | 1972 |
Interaction of 4-nitroquinoline 1-oxide and related carcinogens with histone and aliphatic amino acids.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carcinogens; Cattle; Chemical Phenomena; Chemistry; Glutamates; Glycine; Histones; Isoleucine; Leucine; Lysine; Methionine; Proline; Protein Denaturation; Quinolines; Serine; Spectrophotometry; Threonine; Thymus Gland; Valine | 1972 |
Effects of mother-litter separation on survival, growth, and brain amino acid levels.
Topics: Alanine; Amino Acids; Aminobutyrates; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Aspartic Acid; Body Weight; Brain; Brain Chemistry; Female; Glutamates; Housing, Animal; Lactation; Male; Maternal Behavior; Maternal Deprivation; Organ Size; Pregnancy; Rats; Social Behavior; Threonine; Weaning | 1972 |
Rat liver aminomalonate decarboxylase. Identity with cytoplasmic serine hydroxymethylase and allothreonine aldolase.
Topics: Alanine; Aldehyde-Lyases; Amino Acids; Animals; Binding Sites; Binding, Competitive; Carbon Isotopes; Carboxy-Lyases; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Glycine; Liver; Male; Malonates; Mitochondria, Liver; Molecular Weight; Protein Denaturation; Rats; Serine; Tetrahydrofolates; Threonine; Transferases; Tritium | 1973 |
A growth factor for animal cells derived from peptone. I. Isolation and characterization of the growth factor.
Topics: Alanine; Aspartic Acid; Chromatography, Gel; Chromatography, Paper; Clone Cells; Culture Media; Culture Techniques; Glutamates; Glycine; Growth Substances; L Cells; Lysine; Molecular Weight; Peptones; Serine; Spectrophotometry; Threonine | 1973 |
Surface binding of amino acids by L1210 cells at 4 degrees C.
Topics: Alanine; Amino Acids; Animals; Binding Sites; Biological Transport, Active; Cell Line; Cell Membrane; Histidine; Hydrogen-Ion Concentration; Hydroxylation; Isoleucine; Leucine; Leukemia L1210; Lipids; Mice; Phenylalanine; Solubility; Structure-Activity Relationship; Threonine; Tyrosine; Water | 1973 |
Biosynthesis of branched-chain amino acids in Schizosaccharomyces pombe: regulatory properties of threonine deaminase.
Topics: Alanine; Amino Acids; Ammonium Sulfate; Ascomycota; Chromatography, Gel; Culture Media; Enzyme Activation; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Leucine; Protamines; Pyridoxal Phosphate; Stimulation, Chemical; Temperature; Threonine; Valine | 1973 |
Hyperglutamatemia in primary gout.
Topics: Adult; Aged; Alanine; Ammonia; Chromatography; Fasting; Glutamates; Glutamine; Glycine; Gout; Humans; Male; Metabolism, Inborn Errors; Middle Aged; Serine; Threonine; Uric Acid | 1973 |
The reversal of triparanol-induced cataracts in the rat. 3. Amino acid content and uptake of 14 C -AIB in cataractous and clearing lenses.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Cataract; Cystine; Diet; Glutamates; Glycine; Histidine; Isoleucine; Lens, Crystalline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Serine; Threonine; Triparanol; Tyrosine; Valine | 1973 |
Release of cholecystokinin by amino acids.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Bicarbonates; Cholecystokinin; Cysteine; Dogs; Drug Synergism; Duodenum; Glutamates; Glycine; Intestinal Mucosa; Pancreas; Pancreatic Juice; Perfusion; Phenylalanine; Secretin; Threonine; Tryptophan | 1973 |
Exchange transport between various amino acids and alanine in isolated intestinal epithelial cells.
Topics: Alanine; Amino Acids; Animals; Arginine; Biological Transport; Carbon Isotopes; Epithelial Cells; Epithelium; Histidine; Intestinal Mucosa; Intestines; Isoleucine; Leucine; Lysine; Male; Ornithine; Phenylalanine; Rats; Sodium; Threonine; Time Factors; Tryptophan; Valine | 1973 |
A new destruction of blood group substances. Isolation of glycopeptide containing O-glycosidic carbohydrate-peptide linkage.
Topics: Acetamides; Alanine; Amino Acids; Animals; Autoanalysis; Blood Group Antigens; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis, Paper; Galactosamine; Gastric Mucosa; Glycopeptides; Pronase; Swine; Threonine | 1973 |
Amino acid levels in plasma, liver, and skeletal muscle during protein deprivation.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Body Weight; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Liver; Male; Methionine; Muscles; Organ Size; Phenylalanine; Protein Deficiency; Rats; Serine; Threonine; Time Factors; Tyrosine; Valine | 1973 |
Relationship of protein metabolism to senescence of corn (Zea mays L.) stalk parenchyma, cob parenchyma and first developed leaf tissues.
Topics: Aging; Alanine; Amino Acids; Aspartic Acid; Carbon Isotopes; Cell Count; Chromatography; Dactinomycin; Glutamine; Leucine; Models, Biological; Ornithine; Phenylalanine; Plant Proteins; Plants; Ribonucleases; Ribosomes; RNA; RNA, Messenger; Threonine; Time Factors; Tyrosine | 1973 |
Preparation and kinetic properties of a new form of chymotrypsin which is active at alkaline pH: 1 -chymotrypsin.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Binding, Competitive; Buffers; Cattle; Chemical Phenomena; Chemistry; Chromatography, Affinity; Chymotrypsin; Chymotrypsinogen; Drug Stability; Enzyme Activation; Esters; Hydrogen-Ion Concentration; Kinetics; Protein Conformation; Structure-Activity Relationship; Threonine | 1973 |
The immunoglobulins derived from a VH-CH recombinant rabbit and its normal relatives. II. Chemical studies of allotype related differences in Fd and Fc fragments.
Topics: Alanine; Amino Acids; Animals; Chromatography, Gel; Electrophoresis, Paper; Homozygote; Immunoglobulin Fc Fragments; Immunoglobulin Fragments; Immunoglobulin G; Isoantigens; Papain; Peptides; Rabbits; Recombination, Genetic; Threonine; Trypsin | 1973 |
Alterations in renal and plasma amino acid concentrations during renal compensatory growth.
Topics: Alanine; Amino Acids; Animals; Kidney; Kidney Cortex; Leucine; Male; Methionine; Nephrectomy; Ornithine; Rats; Serine; Starvation; Threonine; Tyrosine | 1973 |
Studies on tyrosine environments of chicken ovomucoid. The environment of the most-exposed tyrosine.
Topics: Absorption; Alanine; Amino Acid Sequence; Amino Acids; Animals; Chickens; Chromatography, Ion Exchange; Chromatography, Thin Layer; Egg Proteins; Glutamine; Glycine; Lysine; Methane; Mucoproteins; Neuraminic Acids; Nitro Compounds; Peptide Fragments; Spectrum Analysis; Threonine; Tyrosine | 1973 |
Biosynthetic precursors of etamycin, a peptidolactone antibiotic from Streptomyces griseoviridus.
Topics: Alanine; Anti-Bacterial Agents; Benzene Derivatives; Carbon Radioisotopes; Glucose; Hydroxyproline; Lactones; Leucine; Lysine; Nitrates; Peptides, Cyclic; Picolinic Acids; Potassium; Proline; Sarcosine; Streptomyces; Structure-Activity Relationship; Threonine; Tritium | 1973 |
Free amino acids and carbohydrates in the cerebrospinal fluid of 305 mentally retarded patients: a screening study.
Topics: Adolescent; Adult; Alanine; Amino Acids; Arginine; Carbohydrates; Child; Child, Preschool; Chromatography, Thin Layer; Cystine; Epilepsy; Female; Glutamates; Glutamine; Humans; Intellectual Disability; Intelligence Tests; Isoleucine; Leucine; Lysine; Male; Metabolism, Inborn Errors; Methionine; Middle Aged; Ornithine; Phenylalanine; Pneumoencephalography; Threonine; Valine | 1973 |
Plasma amino acids in subjects taking oral contraceptives.
Topics: Alanine; Amino Acids; Contraceptives, Oral; Contraceptives, Oral, Combined; Ethynodiol Diacetate; Female; Glycine; Humans; Leucine; Menstruation; Mestranol; Threonine; Time Factors; Valine | 1973 |
Proteolytic modification of the beta nerve growth factor protein.
Topics: Alanine; Alkylation; Amino Acids; Animals; Arginine; Biological Assay; Carboxypeptidases; Chemical Phenomena; Chemistry; Chick Embryo; Drug Stability; Electrophoresis, Disc; Ganglia; Hydrogen-Ion Concentration; Isoelectric Focusing; Macromolecular Substances; Male; Mice; Nerve Growth Factors; Proteins; Submandibular Gland; Threonine | 1974 |
Amino acid metabolism in rats fed a high protein diet without pyridoxine.
Topics: Alanine; Amino Acids; Animals; Autoanalysis; Caseins; Centrifugation; Chromatography, Paper; Creatinine; Dietary Proteins; Glycine; L-Serine Dehydratase; Liver; Lyases; Male; Nitrogen; Protein Biosynthesis; Rats; Threonine; Vitamin B 6 Deficiency | 1974 |
Localization of the histidine-rich protein in keratohyalin: a morphologic and macromolecular marker in epidermal differentiation.
Topics: Alanine; Animals; Animals, Newborn; Arginine; Aspartic Acid; Cell Differentiation; Cytoplasmic Granules; Electrophoresis, Polyacrylamide Gel; Glutamates; Glycine; Histidine; Histocytochemistry; Keratins; Macromolecular Substances; Microscopy, Electron; Microscopy, Electron, Scanning; Rats; Serine; Skin; Threonine; Tritium | 1974 |
Influence of feeding and fasting on plasma free amino acids in the equine.
Topics: Alanine; Amino Acids; Amino Acids, Essential; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Weight; Diet; Fasting; Glutamine; Glycine; Horses; Male; Threonine; Time Factors | 1974 |
An acetylated N-terminus of adenovirus type 2 hexon protein.
Topics: Acetylation; Adenoviridae; Alanine; Amino Acid Sequence; Carbon Radioisotopes; Chromatography, Ion Exchange; Electrophoresis, Paper; Hydrogen-Ion Concentration; Mass Spectrometry; Peptide Fragments; Proline; Serine; Threonine; Time Factors; Viral Proteins | 1974 |
Selective malabsorption of vitamin B 12: report of a case with metabolic studies.
Topics: Alanine; Amino Acids; Anemia, Macrocytic; Child; Chromatography, Gas; Glycine; Hemoglobins; Histidine; Humans; Isoleucine; Leucine; Malabsorption Syndromes; Male; Malonates; Methionine; Proteinuria; Renal Tubular Transport, Inborn Errors; Reticulocytes; Serine; Taurine; Threonine; Tyrosine; Valine; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Hyperglutamatemia in primary gout.
Topics: Administration, Oral; Alanine; Erythrocytes; Glutamates; Glutamine; Glycine; Gout; Humans; Male; Puberty; Serine; Threonine; Time Factors; Uric Acid | 1974 |
Altered amino acid concentrations accompanying suppression of malignancy of mouse melanoma cells by 5-bromodeoxyuridine.
Topics: Alanine; Amino Acids; Animals; Asparagine; Bromodeoxyuridine; Cells, Cultured; Glutamates; Glutamine; Glycine; Lysine; Melanoma; Methionine; Mice; Neoplasm Proteins; Ornithine; Phenylalanine; Pigmentation; Proline; Serine; Threonine; Valine | 1974 |
A simple method for large-scale preparation of chick embryo tRNA.
Topics: Alanine; Animals; Asparagine; Carbon Radioisotopes; Chick Embryo; Chromatography, DEAE-Cellulose; Chromatography, Gel; Evaluation Studies as Topic; Glycine; Hydrogen-Ion Concentration; Methods; RNA, Transfer; Serine; Threonine; Time Factors; Valine | 1974 |
Glycine uptake in Escherichia coli. II. Glycine uptake, exchange, and metabolism by an isolated membrane preparation.
Topics: Alanine; Arsenic; Autoradiography; Azides; Biological Transport; Carbon Isotopes; Cell Membrane; Chromatography, Thin Layer; Cold Temperature; Cyanides; Dinitrophenols; Escherichia coli; Glucose; Glycine; Helium; Hydrazines; Hydrogen-Ion Concentration; Hydroxylamines; Iodoacetates; Magnesium; Mercury; Nucleotides; Phosphatidylethanolamines; Serine; Sulfonic Acids; Threonine | 1968 |
Control of carbon dioxide fixation in Escherichia coli by compounds related to TCA cycle.
Topics: Alanine; Arginine; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Cell-Free System; Citrates; Citric Acid Cycle; Coenzyme A; Depression, Chemical; Escherichia coli; Fumarates; Glutamates; Lactates; Lysine; Malates; Malonates; Ovalbumin; Proline; Pyruvates; Succinates; Tartrates; Threonine | 1968 |
Suppressor selectrion for amino acid replacements expected on the basis of the genetic code.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bacterial Proteins; Escherichia coli; Genes; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Histidine; Hydro-Lyases; Isoleucine; Leucine; Lysine; Methionine; Mutation; Nucleotides; Phenylalanine; RNA, Messenger; Serine; Suppression, Genetic; Threonine; Tyrosine; Valine | 1967 |
The effect of branched chain amino acids on the synthesis of isoleucine from threonine and pyruvate in crude extracts from Escherichia coli.
Topics: Alanine; Aspartic Acid; Chromatography, Thin Layer; Escherichia coli; Isoleucine; Leucine; Pyruvates; Serine; Threonine; Tissue Extracts; Valine | 1970 |
Serine metabolism in the culture form of Trypanosoma cruzi: synthesis of other amino acids.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Ion Exchange; Cysteine; Glutamates; Glycine; Protein Biosynthesis; Proteins; Serine; Threonine; Trypanosoma cruzi | 1971 |
Amino-acid protection of ultra-violet-irradiated Bacillus subtilis.
Topics: Acid-Base Equilibrium; Alanine; Bacillus subtilis; Culture Media; Glycine; Histidine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays | 1966 |
Studies on the specificity of Bacillus subtilis neutral protease with synthetic substrates.
Topics: Alanine; Amino Acid Sequence; Bacillus subtilis; Catalysis; Histidine; Isoleucine; Kinetics; Leucine; Peptide Hydrolases; Peptides; Phenylalanine; Serine; Threonine; Valine | 1967 |
The NH2-terminal residues of Bacillus subtilis proteins.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus subtilis; Carbon Isotopes; Chromatography, Gel; Escherichia coli; Fluorine; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Nitrobenzenes; Proteins; Ribosomes; Serine; Species Specificity; Threonine; Tritium; Valine | 1968 |
On the C-terminal amino acid of bacterial alpha-amylase.
Topics: Alanine; Amino Acid Sequence; Amylases; Aspartic Acid; Bacillus subtilis; Carbon; Chemical Phenomena; Chemistry; Electrophoresis; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Paper; Serine; Threonine; Tyrosine; Valine | 1968 |
Serine-containing active center of alkaline proteinase of Aspergillus flavus.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Arthrobacter; Aspergillus; Bacillus subtilis; Binding Sites; Chromatography, Ion Exchange; Chromatography, Paper; Glycine; Isoflurophate; Methionine; Peptide Hydrolases; Phosphorus Isotopes; Serine; Streptomyces; Threonine; Trypsin | 1969 |
The amino-terminal residues of Bacillus subtilis proteins made in vitro.
Topics: Alanine; Bacillus subtilis; Bacterial Proteins; Carbon Isotopes; Cell-Free System; Chromatography, Gel; Folic Acid; Formates; Kinetics; Methionine; Molecular Weight; Peptide Biosynthesis; Peptide Hydrolases; RNA, Messenger; Serine; Threonine; Tritium; Valine | 1970 |
Plasma amino acid levels in diabetic ketoacidosis.
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Arginine; Butyrates; Child; Citrulline; Cystine; Diabetic Ketoacidosis; Female; Glycine; Histidine; Humans; Insulin; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1970 |
[Threonine deaminease from Arthrobacter strain 23].
Topics: Alanine; Aminobutyrates; Aminoisobutyric Acids; Arthrobacter; Binding Sites; Bromides; Carbohydrates; Cell-Free System; Chemical Precipitation; Culture Media; Edetic Acid; Enzyme Activation; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Leucine; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Sulfates; Threonine; Ultracentrifugation; Valine; Vibration | 1971 |
Carboxy-terminal structure of the chain of human IgA myeloma proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Antigens; Aspartic Acid; Bence Jones Protein; Blood Protein Electrophoresis; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Gel; Cyanides; Cysteine; Glutamates; Glycine; Humans; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin A; Immunoglobulin G; Iodine Isotopes; Methods; Models, Structural; Oxidation-Reduction; Peptides; Rabbits; Sulfides; Thiocyanates; Threonine; Tyrosine; Valine | 1971 |
Serine biosynthesis in Tetrahymena pyriformis S.
Topics: Acetates; Acyltransferases; Alanine; Aldehyde-Lyases; Animals; Carbon Isotopes; Citric Acid Cycle; Fatty Acids; Formates; Glucose; Glutamates; Glycine; Ketoglutaric Acids; Lactates; Protein Biosynthesis; Pyruvates; Serine; Tetrahymena pyriformis; Threonine | 1971 |
Methionine or folate and phosphoenolpyruvate in the biosynthesis of threonine in Crithidia fasciculata.
Topics: Alanine; Carbon Isotopes; Cell-Free System; Chromatography, Paper; Culture Media; Cystine; Eukaryota; Folic Acid; Homocysteine; Homoserine; Hydrazones; Hydroxybutyrates; Keto Acids; Methionine; Methyltransferases; Phosphoenolpyruvate; Sulfonic Acids; Sulfur Isotopes; Threonine | 1972 |
Detection of non-protein amino acids in the presence of protein amino acids. II.
Topics: Alanine; Amino Acids; Autoanalysis; Buffers; Chemical Phenomena; Chemistry; Chromatography; Colorimetry; Cysteine; Hydrogen-Ion Concentration; Isoleucine; Methods; Proteins; Threonine; Urea; Valine | 1972 |
The effect of diethyl- -fluoroglutarate on phosphates and glutamate in slices of rabbit cerebral cortex.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Cerebral Cortex; Esters; Fluorine; Glucose; Glutamate Dehydrogenase; Glutamates; Glutamine; Glutarates; Glycine; Oxidative Phosphorylation; Phosphates; Rabbits; Serine; Threonine | 1972 |
The effect of topical application of diethyl- -fluoroglutarate on the metabolism and electrical activity in vivo of cat cerebral cortex.
Topics: Adenosine Triphosphate; Alanine; Aminobutyrates; Ammonia; Animals; Aspartic Acid; Cats; Cerebral Cortex; Electric Stimulation; Electroencephalography; Esters; Fluorine; Glucose; Glucosephosphates; Glutamates; Glutamine; Glutarates; Glycine; Lactates; Malates; Pyruvates; Serine; Synapses; Thalamic Nuclei; Threonine | 1972 |
Regulation of aspartokinase activity in a thermophilic bacterium.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacteria; Feedback; Homoserine; Isoleucine; Kinetics; Lysine; Methionine; Phosphotransferases; Stereoisomerism; Threonine; Valine | 1972 |
Amino acid metabolism during starvation in human pregnancy.
Topics: Adolescent; Adult; Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Blood Glucose; Female; Food Deprivation; Gluconeogenesis; Glycine; Humans; Hypoglycemia; Isoleucine; Leucine; Pregnancy; Serine; Starvation; Threonine; Time Factors; Valine | 1972 |
Structure and mode of action of glycoproteins from an antarctic fish.
Topics: Acylation; Alanine; Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Blood Physiological Phenomena; Chemical Phenomena; Chemistry; Deuterium; Dimethyl Sulfoxide; Disaccharides; Fishes; Freezing; Galactose; Galactosidases; Glycols; Glycoproteins; Magnetic Resonance Spectroscopy; Models, Structural; Oxidation-Reduction; Plants; Threonine | 1972 |
The aminoaciduria of pregnancy.
Topics: Alanine; Amino Acids; Female; Folic Acid; Glycine; Histidine; Humans; Kidney; Pregnancy; Renal Aminoacidurias; Serine; Statistics as Topic; Threonine | 1972 |
Further observations on protein synthesis by isolated nuclei from rat brain cells.
Topics: Alanine; Animals; Brain; Carbon Isotopes; Cell Nucleus; Cycloheximide; Dactinomycin; Leucine; Nerve Tissue Proteins; Neurons; Puromycin; Rats; Sodium; Threonine; Valine | 1972 |
A basis for the difference in the inhibition of the uptake of various neutral amino acids by lysine in intestinal epithelial cells.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Carbon Isotopes; Epithelial Cells; Epithelium; Histidine; Intestinal Mucosa; Intestines; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Rats; Sodium; Threonine; Tryptophan; Valine | 1972 |
Hypothalamic radioactivity after intragastric glucose- 14 C in rats.
Topics: Alanine; Animals; Carbon Isotopes; Diabetes Mellitus; Feeding Behavior; Food Deprivation; Glucose; Glycine; Hypothalamus; Insulin; Linoleic Acids; Male; Rats; Rats, Inbred Strains; Threonine | 1972 |
Nature of the receptor substance of Mycobacterium smegmatis for D4 bacteriophage adsorption.
Topics: Acetone; Adsorption; Alanine; Amino Acids; Antiviral Agents; Autoanalysis; Chloroform; Chromatography, Paper; Chromatography, Thin Layer; Glycolipids; Hexoses; Infrared Rays; Methanol; Mycobacteriophages; Mycobacterium; Phenylalanine; Solvents; Species Specificity; Spectrophotometry; Threonine | 1972 |
Amino acid patterns in the blood plasma of the young bovine.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Cystine; Female; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1972 |
Endocrine control of free amino acids content in uterine fluid in pregnant rabbits.
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Body Fluids; Castration; Corpus Luteum; Embryo Implantation; Estradiol; Female; Glycine; Ovary; Pregnancy; Progesterone; Rabbits; Serine; Taurine; Threonine; Uterus | 1972 |
[Amino acid sequence of the threonine containing mureins of some species of Streptococcus].
Topics: Alanine; Amino Acid Sequence; Cell Wall; Chromatography, Paper; Chromatography, Thin Layer; Glycine; Peptidoglycan; Phosphates; Serine; Streptococcus; Threonine | 1972 |
Effect of excess levels of individual amino acids on growth of rats fed casein diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Caseins; Cystine; Depression, Chemical; Dietary Proteins; DNA; Glutamates; Glycine; Growth; Histidine; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Organ Size; Phenylalanine; Proline; Proteins; Rats; RNA; Serine; Stereoisomerism; Stimulation, Chemical; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Effect of dietary protein level on plasma free amino acids in the chicken.
Topics: Alanine; Amino Acids; Animals; Blood; Body Weight; Caseins; Chickens; Depression, Chemical; Dietary Proteins; Glycine; Isoleucine; Leucine; Lysine; Male; Methionine; Proline; Proteins; Serine; Stimulation, Chemical; Threonine; Tyrosine; Valine | 1971 |
Quantitative amino acids in amniotic fluid and maternal plasma in early and late pregnancy. Preliminary report.
Topics: Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Arginine; Aspartic Acid; Citrulline; Cystine; Female; Gestational Age; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Chicken heart H 4 lactate dehydrogenase: N-terminal and C-terminal residues.
Topics: Acetamides; Acetates; Alanine; Amino Acid Sequence; Amino Acids; Anhydrides; Animals; Carboxylic Acids; Chemical Phenomena; Chemistry; Chickens; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Dipeptides; Electrophoresis; Hot Temperature; Hydrolysis; Hydroxylamines; L-Lactate Dehydrogenase; Leucine; Myocardium; Peptide Hydrolases; Peptides; Protein Denaturation; Pseudomonas; Pyrrolidinones; Threonine; Tritium | 1971 |
Biosynthesis of riboflavin by Ashbya gossypii. II. The influence of animal proteins on the riboflavin biosynthesis.
Topics: Alanine; Animal Population Groups; Animals; Ascomycota; Autoanalysis; Bone and Bones; Culture Media; Fermentation; Filtration; Gelatin; Glycine; Hydrogen-Ion Concentration; Proline; Proteins; Riboflavin; Skin; Threonine | 1971 |
Quantitative protein sequencing using mass spectrometry: mass spectral analysis of 2-anilino-5-thiazolinone derivatives of amino acids without prior conversion to the phenyl thiohydantoins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aniline Compounds; Animals; Arginine; Autoanalysis; Cattle; Chemical Phenomena; Chemistry; Drug Stability; Glutamates; Hydantoins; Lysine; Mass Spectrometry; Methods; Phenylalanine; Ribonucleases; Serine; Sulfides; Thiazoles; Thiocyanates; Threonine; Tyrosine | 1971 |
Daily variations in the concentrations of individual amino acids in rat plasma.
Topics: Alanine; Amino Acids; Animals; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Phenylalanine; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
The effect of dietary fluoride on plasma free amino acid concentrations in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Diet; Feeding Behavior; Female; Fluorides; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Rats, Inbred Strains; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Effect of substrate structure on coupling ratio for Na + -dependent transport of amino acids.
Topics: Alanine; Amino Acids; Animals; Asparagine; Biological Transport; Carbon Isotopes; Columbidae; Cysteine; Erythrocytes; Hydroxyproline; Kinetics; Models, Biological; Models, Structural; Potassium; Potassium Isotopes; Proline; Serine; Sodium; Sodium Chloride; Sodium Isotopes; Structure-Activity Relationship; Threonine; Tritium | 1971 |
The effect of vitamin C depletion on the free amino acid content in blood plasma of the guinea pig.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Ascorbic Acid Deficiency; Aspartic Acid; Citrulline; Cysteine; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Time Factors; Tyrosine; Valine | 1971 |
Carbohydrate metabolism in pregnancy. IX. Plasma levels of gluconeogenic fuels during fasting in the rat.
Topics: Alanine; Amino Acids; Animals; Carbohydrate Metabolism; Fasting; Female; Gluconeogenesis; Glutamates; Glutamine; Glycerol; Hypoglycemia; Lactates; Pregnancy; Pyruvates; Rats; Serine; Threonine; Time Factors | 1971 |
[Dissociation of S- and P-variants of Bacillus brevis var. G.-B. on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Mutation; Nitrogen; Ornithine; Phenylalanine; Serine; Stimulation, Chemical; Threonine; Time Factors; Tryptophan; Valine | 1971 |
[Antineoplastic effect and chemical structure of protamines of various origin].
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Depression, Chemical; Fishes; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Leukemia, Experimental; Lysine; Methionine; Mice; Proline; Protamines; Sarcoma 37; Serine; Threonine | 1971 |
[Behavior of serum amino acids in rats with experimentally produced hyperphenylalaninemia].
Topics: Alanine; Amino Acids; Animals; Disease Models, Animal; Glutamates; Phenylalanine; Proline; Rats; Threonine | 1971 |
Beef heart H 4 lactate dehydrogenase: N-terminal and C-terminal residues.
Topics: Acetates; Alanine; Animals; Cattle; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis; Electrophoresis, Paper; Fluorine; Isoenzymes; L-Lactate Dehydrogenase; Leucine; Myocardium; Nitrobenzenes; Peptides; Phenylalanine; Pronase; Sulfonic Acids; Thiocyanates; Threonine; Tritium | 1971 |
Similarities and differences among specific tRNA's in mammalian tissues.
Topics: Alanine; Animals; Brain Chemistry; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cattle; Chick Embryo; Culture Techniques; Fibroblasts; Glycine; HeLa Cells; Humans; Kidney; Leucine; Liver; Lysine; Mice; Muscles; Neoplasms, Experimental; Phenylalanine; Rabbits; RNA, Transfer; Serine; Species Specificity; Threonine; Tritium | 1967 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Isoaccepting transfer RNA's of L-M cells in culture and after tumor induction in C3H mice.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cell Line; Chromatography; Connective Tissue; Culture Media; Culture Techniques; Female; Fibrosarcoma; Glycine; Histidine; Isoleucine; Leucine; Ligases; Lysine; Male; Methionine; Mice; Phenylalanine; Proline; RNA, Transfer; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
[Distribution of free amino acids in plasma in patients with a chronic lymphatic and acute leukemia].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Citrulline; Cystine; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Leukemia, Lymphoid; Lysine; Methionine; Ornithine; Phenylalanine; Prednisolone; Proline; Serine; Threonine; Triethylenemelamine; Tyrosine; Valine; Vincristine | 1971 |
Observations on the plasma amino acids of patients with acute leukemia.
Topics: Acute Disease; Alanine; Amino Acids; Asparaginase; Cytarabine; Glucocorticoids; Glutamine; Histidine; Humans; Indicators and Reagents; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Methionine; Methotrexate; Nitrogen; Proline; Threonine; Vincristine | 1971 |
Effects of ionizing radiation on free amino acids in Oedogonium cardiacum.
Topics: Alanine; Chromatography, Thin Layer; Eukaryota; Glutamates; Glycine; Histidine; Leucine; Methionine; Ornithine; Radiation Effects; Serine; Threonine; Valine | 1966 |
Enzymatic formation of beta-cyanoalanine from cyanide by Escherichia coli extracts.
Topics: Adenosine Triphosphate; Alanine; Carbon Isotopes; Chemical Phenomena; Chemistry; Cyanides; Cysteine; Escherichia coli; Magnesium; Serine; Sulfides; Threonine | 1965 |
Imidazolylacetolphosphate:L-glutamate aminotransferase. Composition and substructure.
Topics: Alanine; Ammonia; Arginine; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Electrophoresis; Genes; Glycine; Histidine; Leucine; Methionine; Molecular Biology; Molecular Weight; Peptides; Phenylalanine; Proline; Salmonella typhimurium; Serine; Threonine; Transaminases; Tyrosine; Valine | 1967 |
Studies on polynucleotides. LXXIV. Direct translation in vitro of single-stranded DNA-like polymers with repeating nucleotide sequences in the presence of neomycin B.
Topics: Alanine; Carbon Isotopes; Chromatography, Paper; Cysteine; DNA, Bacterial; Escherichia coli; Genetic Code; Histidine; Methionine; Neomycin; Peptide Biosynthesis; Polynucleotides; Ribosomes; RNA, Transfer; Thiocyanates; Threonine; Valine | 1967 |
[Endogenous pellagra without hyperaminoaciduria].
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Arginine; Chromatography, Paper; Diagnosis, Differential; Electroencephalography; Glutamates; Glutamine; Hartnup Disease; Histidine; Humans; Lysine; Male; Pellagra; Serine; Skin Manifestations; Threonine | 1969 |
Studi on siomycin. II. The composition and degradation products of siomycin A.
Topics: Acetaldehyde; Alanine; Amino Acids; Anti-Bacterial Agents; Butyrates; Carbon; Chemical Phenomena; Chemistry; Cysteine; Optical Rotatory Dispersion; Oxidation-Reduction; Propionates; Pyruvates; Quinazolines; Thiazoles; Threonine; Valine | 1969 |
Changes in free amino acids of tomato fruit under pathogenesis.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Fruit; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Plant Diseases; Serine; Threonine; Tyrosine; Valine | 1969 |
Effect of cholesteryl 14-methylhexadecanoate on the activity of some amino acid-transfer ribonucleic acid ligases from mammalian tissues.
Topics: Alanine; Animals; Carbon Isotopes; Ligases; Liver; Pancreas; Rats; RNA, Transfer; Sterols; Threonine; Tritium; Tryptophan; Tyrosine | 1969 |
[Incorporation of amino acids into C2 mycoside of Mycobacterium avium].
Topics: Alanine; Amino Acids; Carbon Isotopes; Chromatography, Paper; Glycoproteins; Mycobacterium; Phenylalanine; Threonine | 1969 |
Transaminase activity in sheep rumen content.
Topics: Alanine; Alanine Transaminase; Animals; Arginine; Aspartic Acid; Cysteine; Eukaryota; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Leucine; Methionine; Phenylalanine; Rumen; Serine; Sheep; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
[Chemical and physico-chemical properties of placental protein with antineoplastic effect].
Topics: Alanine; Amino Acids; Ammonia; Antineoplastic Agents; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Electrophoresis; Female; Glutamates; Glycine; Histidine; Humans; Leucine; Lysine; Phenylalanine; Placenta; Proline; Proteins; Serine; Threonine; Tyrosine; Valine | 1969 |
[On the influence of contraceptive pills on serum amino acids in comparison with results typical for sex, menstrual cycle and pregnancy].
Topics: Adult; Alanine; Amino Acids; Citric Acid Cycle; Contraceptives, Oral; Female; Glycine; Humans; Isoleucine; Leucine; Male; Menstruation; Methionine; Pregnancy; Proline; Sex Factors; Threonine; Tyrosine; Urea; Valine | 1969 |
Study on the amino acid composition in the cornea of hypophysectomized rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cornea; Cystine; Electrophoresis; Glutamates; Glycine; Growth Hormone; Histidine; Hypophysectomy; Leucine; Lysine; Methionine; Phenylalanine; Pituitary Gland; Rats; Serine; Threonine; Tyrosine | 1969 |
Amino acid content of muscle and plasma with altered pH.
Topics: Acidosis, Respiratory; Alanine; Alkalosis; Amino Acids; Animals; Aspartic Acid; Carbon Dioxide; Cell Membrane; Citrulline; Extracellular Space; Glutamine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Male; Muscles; Partial Pressure; Potassium Deficiency; Rats; Serine; Threonine; Valine | 1970 |
The control by insulin of amino acid accumulation in muscle.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Cycloheximide; Ethionine; Histidine; In Vitro Techniques; Insulin; Leucine; Methyltyrosines; Muscles; Nucleic Acids; Proteins; Rats; Stimulation, Chemical; Threonine | 1970 |
Rates of synthesis and degradation of protein in the sea urchin embryo.
Topics: Alanine; Animals; Carbon Isotopes; Echinodermata; Embryo, Nonmammalian; Histidine; Kinetics; Phenylalanine; Proline; Protein Biosynthesis; Threonine; Valine | 1970 |
Levels of amino acids and proteins in Pacinian corpuscles of the cat.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cats; Chromatography, Paper; Denervation; Glutamates; Glutamine; Glycine; Mesentery; Nerve Endings; Nerve Tissue Proteins; Pargyline; Reserpine; Serine; Threonine | 1970 |
The amino acid composition of gray matter ganglioside-peptides of normal human and Tay-Sachs brains.
Topics: Alanine; Amino Acids; Aspartic Acid; Brain Chemistry; Chromatography, Ion Exchange; Cystine; Gangliosides; Glycine; Humans; Isoleucine; Leucine; Lipidoses; Methionine; Peptides; Threonine; Trypsin; Tyrosine; Valine | 1970 |
Derivation of partial sequence of human beta chain messenger RNA from mutation data.
Topics: Alanine; Arginine; Genetic Code; Glycine; Hemoglobins; Humans; Leucine; Mutation; Nucleotides; Proline; RNA, Messenger; Serine; Threonine; Valine | 1970 |
[Study of chemical composition and antineoplastic effect of protamines isolated from the milt of sturgeon fishes].
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Chromatography, Thin Layer; Depression, Chemical; Electrophoresis; Fishes; Glutamates; Glycine; Histidine; Leucine; Lysine; Male; Methionine; Mice; Molecular Weight; Neoplasms, Experimental; Nucleic Acids; Proline; Protamines; Sarcoma 37; Serine; Spectrum Analysis; Sulfates; Threonine; Ultraviolet Rays | 1970 |
Circadian ythm of human urinary amino acid excretion in fed and fasted states.
Topics: 17-Hydroxycorticosteroids; Adult; Alanine; Amino Acids; Asparagine; Circadian Rhythm; Cystinuria; Fasting; Feeding Behavior; Glutamates; Glutamine; Glycine; Humans; Male; Middle Aged; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1970 |
[Biosynthesis of gramicidin C on synthetic media with amino acids as the only N source].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Tyrothricin; Valine | 1970 |
Droplet countercurrent chromatography.
Topics: Alanine; Amino Acids; Chromatography; Countercurrent Distribution; Cystine; Dinitrophenols; Fluorocarbon Polymers; Ornithine; Proline; Serine; Threonine | 1970 |
Changes in the concentration of specific amino acids in the serum of experimentally malnourished pigs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Dietary Proteins; Female; Gluconeogenesis; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Protein Deficiency; Serine; Swine; Threonine; Tyrosine; Valine | 1970 |
A specific apoprotein activator for lipoprotein lipase.
Topics: Adipose Tissue; Alanine; Animals; Drug Synergism; Enzyme Activation; Glutamates; Glutamine; Lipoprotein Lipase; Lipoproteins; Male; Phospholipids; Proteins; Rats; Testis; Threonine; Triglycerides; Valine | 1970 |
The major genetic variant macropeptides of kappa-casein--a comparison of their amino acid contents and tryptic peptides.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Carbohydrates; Caseins; Cattle; Chemical Phenomena; Chemistry; Chromatography, Paper; Electrophoresis; Genetic Code; Isoleucine; Models, Biological; Mutation; Peptides; Threonine; Trypsin | 1970 |
Amino acid sequence analysis with methyl isothiocyanate. Resolution of the methylthiohydantoins by gas-liquid partition chromatography.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Bence Jones Protein; Cattle; Chromatography, Gas; Cysteine; Dipeptides; Glutamates; Hydantoins; Indicators and Reagents; Insulin; Methods; Serine; Serum Albumin, Bovine; Solvents; Thiocyanates; Threonine | 1970 |
Histidinemia.
Topics: Acetates; Acrylates; Adolescent; Alanine; Glycine; Histidine; Humans; Imidazoles; Lactates; Lyases; Male; Metabolism, Inborn Errors; Purpura, Thrombocytopenic; Pyruvates; Serine; Threonine | 1970 |
Determination of pico-mole quantities of gamma-amino-butyric acid (GABA) and serotonin.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoradiography; Brain Chemistry; Carbon Isotopes; Cerebellum; Chromatography; Cysteine; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methods; Microchemistry; Phenylalanine; Proline; Radionuclide Imaging; Rats; Serine; Serotonin; Threonine; Tyrosine; Valine | 1970 |
Amino acid permeability of pea chloroplasts as measured by osmotically determined reflection coefficients.
Topics: Alanine; Amides; Amino Acids; Cell Membrane Permeability; Chloroplasts; Glycine; Imines; Isoleucine; Leucine; Methionine; Osmolar Concentration; Osmotic Pressure; Phenylalanine; Plants; Proline; Serine; Sucrose; Threonine; Valine | 1970 |
Quantitative cation-exchange chromatographic analysis of free amino acids in human amniotic fluid collected during early pregnancy.
Topics: Alanine; Amino Acids; Amino Alcohols; Aminobutyrates; Amniotic Fluid; Autoanalysis; Chromatography, Ion Exchange; Female; Fetus; Glutamates; Glutamine; Glycine; Humans; Lysine; Pregnancy; Proline; Threonine; Time Factors; Valine | 1970 |
Indications of spatial relations among structures recognizing amino acids and Na+ at a transport receptor site.
Topics: Alanine; Amino Acids; Animals; Arginine; Binding Sites; Biological Transport; Canavanine; Columbidae; Erythrocytes; Guanidines; Lysine; Models, Biological; Models, Structural; Ornithine; Proline; Propionates; Rabbits; Reticulocytes; Serine; Sodium; Threonine | 1970 |
A lipoprotein characterizing obstructive jaundice. II. Isolation and partial characterization of the protein moieties of low density lipoproteins.
Topics: Alanine; Albumins; Amino Acids; Chemical Precipitation; Chemistry Techniques, Analytical; Cholestasis; Ethanol; Heparin; Humans; Immunochemistry; Immunoelectrophoresis; Lipoproteins; Peptides; Proteins; Serine; Threonine; Ultracentrifugation | 1970 |
Isolation and characterization of a lysine-sensitive aspartokinase from a multicellular plant.
Topics: Adenosine Triphosphate; Alanine; Aspartic Acid; Enzyme Activation; Isoleucine; Kinetics; Leucine; Lysine; Magnesium; Manganese; Methionine; Phosphotransferases; Plants; Threonine; Valine; Zea mays | 1970 |
The effect on the nitrogen balance of the ratio essential-non-essential amino acids in intravenously infused solutions.
Topics: Adult; Alanine; Amino Acids; Arginine; Aspartic Acid; Blood Urea Nitrogen; Female; Glycine; Histidine; Humans; Infusions, Parenteral; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Proline; Threonine; Tryptophan; Valine | 1970 |
Chemical and physical properties of freezing point-depressing glycoproteins from Antarctic fishes.
Topics: Alanine; Animals; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cold Temperature; Electrophoresis; Fishes; Freezing; Galactose; Glycoproteins; Hexosamines; Molecular Weight; Proteins; Sodium Chloride; Solutions; Spectrum Analysis; Threonine; Viscosity | 1970 |
Studies of the structure of freezing point-depressing glycoproteins from an Antarctic fish.
Topics: Alanine; Amino Acids; Aminobutyrates; Anhydrides; Animals; Carboxypeptidases; Chemical Phenomena; Chemistry; Chymotrypsin; Cold Temperature; Disaccharides; Fishes; Freezing; Galactosidases; Glycoproteins; Leucyl Aminopeptidase; Oligosaccharides; Oxidation-Reduction; Peptide Hydrolases; Sodium Hydroxide; Threonine; Trypsin | 1970 |
[Effect of amino acids on the growth of Streptococcus lactis and biosynthesis of nisin].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Depression, Chemical; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Stimulation, Chemical; Streptococcus; Threonine; Tryptophan; Valine | 1970 |
Properties and substrate specificity of the leucyl-, the threonyl- and the valyl-transfer-ribonucleic acid synthetases from Aesculus species.
Topics: Alanine; Chromatography, DEAE-Cellulose; Glycine; Isoleucine; Leucine; Ligases; Phosphorus Isotopes; Plants; RNA, Transfer; Seeds; Threonine; Valine | 1970 |
Amino acid sequence at the active center of succinate dehydrogenase.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Flavin-Adenine Dinucleotide; Flavins; Histidine; Myocardium; Peptides; Serine; Succinate Dehydrogenase; Thiocyanates; Threonine; Valine | 1970 |
Effect of vitamin B6 depletion in adult man on the plasma concentration and the urinary excretion of free amino acids.
Topics: Adult; Alanine; Amino Acids; Fasting; Glycine; Humans; Isoleucine; Leucine; Male; Pyridoxine; Serine; Threonine; Valine; Vitamin B 6 Deficiency | 1971 |
The effect of an oral glucose load on serum free amino acid concentrations in children before and after treatment for kwashiorkor.
Topics: Alanine; Amino Acids; Blood Glucose; Child, Preschool; Dietary Carbohydrates; Glucose; Glycine; Humans; Infant; Kwashiorkor; Leucine; Muscle Proteins; Threonine; Valine | 1971 |
[The flagellar apparatus of Rhodopseudomonas palustris. VI. Characterization of flagellin].
Topics: Alanine; Aspartic Acid; Bacterial Proteins; Electrophoresis; Flagella; Gels; Glycine; Leucine; Molecular Weight; Pseudomonas; Serine; Threonine; Ultracentrifugation | 1971 |
Nutrient media for plant-parasitic nematodes. II. Amino acid requirements of Aphelenchoides sp.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Fungi; Germ-Free Life; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Nematoda; Nutritional Requirements; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Amino acid metabolism in the isolated perfused rat liver.
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Chromatography; Glutamates; Glycine; In Vitro Techniques; Liver; Lysine; Male; Methionine; Nitrogen Isotopes; Perfusion; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Urea | 1971 |
[Identification of antibacterial antibiotics mutabillicin and sporangiomycin].
Topics: Actinomyces; Alanine; Amino Acids; Anti-Bacterial Agents; Ascomycota; Carbon; Chromatography, Thin Layer; Cystine; Electrophoresis; Hydrogen; Infrared Rays; Leucine; Nitrogen; Solubility; Spectrum Analysis; Sulfur; Threonine; Tyrosine; Ultraviolet Rays; Valine | 1971 |
[Dissociation of R- and P plus-variants of Bacillus brevis var. G.-B. during growth on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Valine | 1971 |
Serine transhydroxymethylase. Affinity of the active site for substrates, substrate analogues, and anions.
Topics: Alanine; Aldehydes; Aminoisobutyric Acids; Animals; Benzoates; Binding Sites; Chlorides; Cysteamine; Cysteine; Electrophoresis; Folic Acid; Glycine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Models, Biological; Organophosphonates; Phosphates; Potassium; Propionates; Pyridoxal Phosphate; Rabbits; Serine; Spectrophotometry; Stereoisomerism; Sulfates; Sulfhydryl Compounds; Sulfonic Acids; Thermodynamics; Threonine; Transferases; Ultracentrifugation | 1971 |
The influence of various -alkyl and -hydroxyalkyl substituents on the stability of dipeptides in dilute alkali.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Borates; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Dipeptides; Drug Stability; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Isomerism; Kinetics; Leucine; Potassium; Serine; Stereoisomerism; Threonine; Valine | 1971 |
Essential amino acids in the culture of Leishmania tarentolae.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Glucose; Glutamates; Glycine; Histidine; Leishmania; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Metabolism of amino acids in plants. I. Changes in the soluble amino acid fractions of bushbean seedlings (Phaseolus vulgaris L.) and the development of transaminase activity.
Topics: Alanine; Alanine Transaminase; Amino Acids; Asparagine; Aspartate Aminotransferases; Cadmium; Chromatography, Paper; Colorimetry; Darkness; Indenes; Ketones; Light; Nitrogen; Plant Development; Plant Physiological Phenomena; Plant Proteins; Plants; Radiation Effects; Seeds; Serine; Solubility; Threonine; Time Factors; Transaminases; Trichloroacetic Acid; Valine | 1971 |
Molecular transport. I. In vivo studies of transport mutants of Neurospora crassa with altered amino acid competition patterns.
Topics: Alanine; Arginine; Aspartic Acid; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Crosses, Genetic; Genetics, Microbial; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Serine; Stereoisomerism; Threonine; Tyrosine; Valine | 1971 |
The free amino acid concentrations in maternal and foetal plasmas in the pregnant ewe.
Topics: Alanine; Amino Acids; Animals; Chromatography, Ion Exchange; Female; Fetus; Glycine; Maternal-Fetal Exchange; Pregnancy; Pregnancy, Animal; Serine; Sheep; Threonine; Umbilical Arteries; Umbilical Veins | 1971 |
[Free amino acids and other ninhydrin-positive substances in the normal horny layer and in psoriasis scales].
Topics: Alanine; Amino Acids; Ammonia; Asparagine; Chromatography; Citrulline; Cysteine; Glycine; Histidine; Humans; Imidazoles; Phenylalanine; Proline; Psoriasis; Serine; Skin; Taurine; Threonine; Urea | 1967 |
[Chemistry of the antibiotic A-128 (neotelomycin)--qualitative and quantitative amino acid composition].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Aspartic Acid; Chemistry Techniques, Analytical; Chromatography, Paper; Electrophoresis; Glycine; Proline; Serine; Threonine; Tryptophan | 1967 |
[Biosphere products of Sinapis alba. I. Rhizosphere products].
Topics: Alanine; Amino Acids; Aminobutyrates; Arabinose; Arginine; Aspartic Acid; Citrates; Cysteine; Glucose; Glutamates; Glycine; Hexoses; Histidine; Keto Acids; Leucine; Mannose; Mustard Plant; Oxalates; Pentoses; Plants, Medicinal; Proline; Ribose; Threonine; Valine; Xylose | 1967 |
[Hyperaminoaciduria in children suffering from progressive muscular dystrophy].
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Arginine; Aspartic Acid; Child; Child, Preschool; Creatine; Creatinine; Female; Glutamates; Histidine; Humans; Leucine; Lysine; Male; Methionine; Muscular Dystrophies; Nitrogen; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
[Quantitative paper chromatography amino acid determination. Stanardization of the procedure and method of testing of new paper types].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography, Paper; Cysteine; Glutamates; Glycine; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Methods; Paper; Phenylalanine; Serine; Spectrum Analysis; Sulfones; Threonine; Tyrosine; Ultraviolet Rays; Valine | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Biosynthesis of the peptidoglycan of bacterial cell walls. VI. Incorporation of L-threonine into interpeptide bridges in Micrococcus roseus.
Topics: Alanine; Carbon Isotopes; Cell Wall; Chromatography, Paper; Glycoproteins; Micrococcus; Muramidase; Peptide Biosynthesis; Polysaccharides, Bacterial; RNA, Transfer; Threonine | 1968 |
Two trypsin inhibitors from porcine pancreatic juice.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Enzyme Precursors; Glutamates; Glutamine; Guanidines; In Vitro Techniques; Kallikreins; Molecular Weight; Pancreatic Juice; Proline; Serine; Species Specificity; Spectrum Analysis; Swine; Threonine; Trypsin; Trypsin Inhibitors; Ultracentrifugation; Ultraviolet Rays | 1968 |
Multivalent feedback inhibition of aspartokinase in Bacillus polymyxa. I. Effect of nonpolar L-amino acids.
Topics: Acetates; Alanine; Amino Acids; Anhydrides; Aspartic Acid; Bacillus; Binding Sites; Detergents; Drug Antagonism; Drug Synergism; Feedback; Glycine; Hot Temperature; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Phosphotransferases; Threonine; Tryptophan; Valine | 1968 |
The erythrocyte plasma distribution of amino acids in health and disease.
Topics: Acute Disease; Adolescent; Adult; Alanine; Amino Acids; Anemia, Hemolytic; Anemia, Pernicious; Bronchitis; Bronchopneumonia; Chromatography, Paper; Erythrocytes; Female; Glutamates; Glutamine; Glycine; Hepatitis; Humans; Hyperthyroidism; Infections; Inflammation; Isoleucine; Leucine; Male; Methionine; Neoplasms; Plasma; Pyelitis; Serine; Threonine; Valine | 1968 |
Isolation and identification of alpha-amino aldehydes in collagen.
Topics: Air Sacs; Alanine; Aldehydes; Amino Alcohols; Animals; Aspartic Acid; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Thin Layer; Collagen; Cyprinidae; Gelatin; Glycine; Hydrazones; Lactones; Lysine; Oxidation-Reduction; Rats; Serine; Skin; Spectrum Analysis; Threonine; Tritium | 1968 |
The distribution of amino acids between erythrocytes and plasma in fetal and maternal blood.
Topics: Alanine; Amino Acids; Biological Transport, Active; Chromatography, Paper; Erythrocytes; Female; Glutamates; Glutamine; Glycine; Humans; Infant, Newborn; Isoleucine; Leucine; Maternal-Fetal Exchange; Methionine; Placenta; Plasma; Pregnancy; Serine; Threonine; Valine | 1968 |
Amino acid constituents of stendomycin.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Antifungal Agents; Arginine; Chromatography, Ion Exchange; Chromatography, Thin Layer; Glycine; Isoleucine; Magnetic Resonance Spectroscopy; Peptides; Proline; Spectrum Analysis; Threonine; Valine | 1968 |
Chemical studies on bleomycins. I. The acid hydrolysis products of bleomycin A2.
Topics: Alanine; Antibiotics, Antineoplastic; Electrophoresis; Hydrochloric Acid; Infrared Rays; Magnetic Resonance Spectroscopy; Spectrum Analysis; Threonine; Ultraviolet Rays; Valerates | 1968 |
A study of 2,4,6-trinitrobenzenesulfonic acid for automated amino acid chromatography.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Autoanalysis; Chromatography; Cystine; Glycine; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Isoleucine; Leucine; Lysine; Methionine; Methods; Nitrobenzenes; Phenylalanine; Proline; Serine; Spectrophotometry; Sulfonic Acids; Temperature; Threonine; Tryptophan; Tyrosine; Urea; Valine | 1968 |
Primary structure of insoluble tendon collagen. 3. Analysis of products of tryptic digestion of native collagen.
Topics: Achilles Tendon; Alanine; Aldehydes; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cysteine; Electrophoresis; Glutamine; Glycine; Hexosamines; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Proline; Serine; Sulfur; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Calf and pea histone IV. I. Amino acid compositions and the identical COOH-terminal 19-residue sequence.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Evolution; Bromine; Cattle; Chromatography, Gel; Chymotrypsin; Cyanides; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Plants; Proline; Serine; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Two procedures for accelerated separation of amino acids by column chromatography.
Topics: Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Buffers; Chromatography, Ion Exchange; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Methods; Phenylalanine; Proline; Serine; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Carbohydrate formation from various precursors in noenatal rat liver.
Topics: Alanine; Animals; Animals, Newborn; Carbon Isotopes; Caseins; Gluconeogenesis; Glucose; Glycerol; Glycogen; Hydro-Lyases; In Vitro Techniques; Lactates; Liver; Oxaloacetates; Rats; Serine; Threonine | 1968 |
Role of streptomycin in the life of Streptomyces griseus: streptidine-containing fractions in the cell walls of Streptomyces griseus strains.
Topics: Alanine; Arginine; Cell Wall; Chromatography, Ion Exchange; Chromatography, Paper; Guanidines; Hydrogen-Ion Concentration; Infrared Rays; Methods; Serine; Spectrum Analysis; Streptomyces; Streptomycin; Threonine | 1968 |
Amino acid binding to luteinizing hormone.
Topics: Acetates; Alanine; Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Cellulose; Chromatography, Gel; Countercurrent Distribution; Electrophoresis; Glycine; Glycoproteins; Guanidines; Luteinizing Hormone; Peptides; Protein Binding; Serine; Sheep; Threonine | 1968 |
Autodigestion of the main proteolytically active component of the stem bromelain.
Topics: Alanine; Arginine; Bromelains; Chromatography; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Peptides; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1968 |
Amino acids involved in chromophore-protein linkages in phycoerythrins.
Topics: Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Pigments, Biological; Proteins; Serine; Threonine | 1968 |
[Levels of free amino acids in the blood and heart muscle in the human at various periods of myocardial infarct (clinical anatomical parallels)].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Erythrocytes; Glutamates; Glycine; Histidine; Histocytochemistry; Humans; Isoleucine; Leucine; Lysine; Methods; Middle Aged; Myocardial Infarction; Myocardium; Necrosis; Phenylalanine; Serine; Threonine; Time Factors; Tyrosine; Valine | 1968 |
Number of polypeptide components in bacteriophage T2L contractile sheaths.
Topics: Alanine; Amino Acids; Aspartic Acid; Carboxypeptidases; Coliphages; Glutamine; Glycine; Hydrazines; Leucine; Peptides; Serine; Threonine; Tryptophan; Valine | 1968 |
[Crystalline leucine aminopeptidase from bovine lens. Amino acid composition and N-terminal amino acids, II].
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Cattle; Crystallography; Formates; Glutamates; Glutamine; Glycine; Lens, Crystalline; Leucine; Leucyl Aminopeptidase; Lysine; Serine; Threonine | 1968 |
Determination of dinitrophenylamino acids in structural proteins by chromatography on nylon powder columns. II. The ether-soluble dinitrophenylamino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography; Dinitrophenols; Glutamates; Glycine; Hydrogen-Ion Concentration; Methods; Nylons; Proteins; Serine; Threonine; Valine | 1969 |
Action of alpha-methyl-DL-tryptophan in vivo on catabolism of amino acids and their conversion to liver glycogen.
Topics: Acetates; Adrenal Glands; Adrenalectomy; Alanine; Amino Acids; Animals; Body Temperature; Carbon Dioxide; Carbon Isotopes; Glutamates; Histidine; Isoleucine; Leucine; Liver; Liver Glycogen; Male; Pyruvates; Rats; Threonine; Time Factors; Tryptophan; Tryptophan Oxygenase; Urea | 1969 |
Effect of glucagon on concentration of several free amino acids in plasma.
Topics: Alanine; Amino Acids; Arginine; Citrulline; Cystine; Depression, Chemical; Fasting; Female; Glucagon; Glycine; Histidine; Humans; Leucine; Liver; Lysine; Male; Methionine; Nitrogen; Phenylalanine; Progesterone; Proline; Serine; Threonine; Tyrosine; Valine | 1969 |
Amino acid composition of gluten fractions.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chemical Precipitation; Dialysis; Glutamates; Glutens; Glycine; Hydrogen-Ion Concentration; Lysine; Magnesium Sulfate; Papain; Proline; Salicylates; Sulfates; Sulfites; Threonine; Tryptophan | 1969 |
Circadian periodicity of blood amino acids in normal and adrenalectomized mice.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Circadian Rhythm; Cystine; Densitometry; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Mice; Serine; Threonine; Tryptophan; Tryptophan Oxygenase; Tyrosine; Valine | 1969 |
Taxonomic comparison of the amino termini of microbial cell proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Bacteria; Bacterial Proteins; Biological Evolution; Eukaryota; Fungi; Methionine; Proteins; Serine; Threonine | 1969 |
Encephalopathy in combination with a new pattern of aminoaciduria.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Brain; Brain Diseases; Central Nervous System; Chromatography; Cyanosis; Dyspnea, Paroxysmal; Electroencephalography; Exchange Transfusion, Whole Blood; Humans; Hyperbilirubinemia; Infant; Infant, Newborn; Infant, Premature, Diseases; Male; Serine; Spectrophotometry; Threonine | 1969 |
Urinary amino acid and peptide excretion patterns in patients with muscular dystrophy (Duchenne). A preliminary study with the autoanalyzer.
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Autoanalysis; Child; Child, Preschool; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Muscular Dystrophies; Peptides; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1969 |
The effect of monovalent cations on the incorporation of various amino acids in protein synthesis by isolated rat spleen nuclei.
Topics: Alanine; Amino Acids; Animals; Carbon Isotopes; Cell Nucleus; Glycine; Leucine; Lithium; Methionine; Phenylalanine; Potassium; Proline; Protein Biosynthesis; Rats; Rubidium; Sodium; Spleen; Stimulation, Chemical; Threonine | 1969 |
Urinary amino acid patterns in simple and complicated bilharziasis.
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Ascites; Chromatography, Paper; Cystinuria; Hepatomegaly; Humans; Liver Diseases; Male; Middle Aged; Schistosomiasis; Splenomegaly; Threonine; Tryptophan; Tyrosine | 1969 |
Free amino acids in serum of patients with chronic renal insufficiency.
Topics: Adult; Aged; Alanine; Amino Acids; Analysis of Variance; Arginine; Chromatography, Paper; Cystine; Female; Glomerulonephritis; Glutamates; Glycine; Humans; Leucine; Lysine; Male; Middle Aged; Phenylalanine; Pyelonephritis; Threonine; Urea; Uremia | 1969 |
Direct synthesis of p-methoxybenzyl carbazate and p-methoxybenzyloxycarbonylamino acids using p-methoxybenzyl chloroformate as reagent.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chloroform; Glutamates; Glutamine; Glycine; Hydrazines; Indicators and Reagents; Isoleucine; Leucine; Phenylalanine; Proline; Sodium Hydroxide; Stereoisomerism; Threonine; Tyrosine; Valine | 1969 |
Chemical studies on the structure of mucopeptide isolated from Streptococcus bovis.
Topics: Alanine; Cell Wall; Chromatography, Ion Exchange; Glucosamine; Glutamates; Lysine; Mucoproteins; Streptococcus; Threonine | 1969 |
Amino acid composition of beta-caseins from the milks of Bos indicus and Bos taurus cows: a comparative study.
Topics: Acrylates; Alanine; Amino Acids; Animals; Arginine; Autoanalysis; Caseins; Cattle; Cellulose; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Electrophoresis; Gels; Glutamates; Histidine; Lysine; Milk; Peptides; Phosphorus; Serine; Species Specificity; Threonine; Trypsin; Tryptophan | 1969 |
The influence of transplantable rat mammary carcinomas on the chemical composition of the host.
Topics: Alanine; Amino Acids; Animals; Arachidonic Acids; Carcinoma 256, Walker; Chromatography, Thin Layer; Fatty Acids; Fatty Acids, Nonesterified; Female; Glutamates; Leucine; Lipid Metabolism; Liver; Mammary Neoplasms, Experimental; Methylcholanthrene; Muscles; Neoplasm Transplantation; Oleic Acids; Palmitic Acids; Phospholipids; Rats; Threonine; Tyrosine | 1969 |
Structure of Mn2+ and Cu2+ complexes with L-methionine, S-methyl-L-cysteine, L-threonine and L-serine.
Topics: Alanine; Amino Acids; Aminobutyrates; Binding Sites; Chemical Phenomena; Chemistry; Copper; Cysteine; Drug Stability; Keto Acids; Magnetic Resonance Spectroscopy; Manganese; Methionine; Serine; Sulfur; Threonine | 1969 |
Histones in early embryogenesis.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Echinodermata; Electrophoresis; Embryo, Nonmammalian; Fishes; Gels; Genetic Code; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
Isolation of a glycopeptide from a 7S protein in soybean globulins.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Globulins; Glucosamine; Glutamates; Glycine; Glycine max; Glycoproteins; Mannose; Molecular Weight; Monosaccharides; Polysaccharides; Serine; Threonine | 1969 |
A method for the determination of free plasma amino acids in ultra-micro quantities.
Topics: Alanine; Amino Acids; Blood Chemical Analysis; Electrophoresis; Histidine; Humans; In Vitro Techniques; Leucine; Microchemistry; Ornithine; Radiotherapy; Serine; Threonine; Urine; Valine | 1965 |
Stimulation of the binding of aminoacyl-sRNA to ribosomes by tubercidin (7-deazaadenosine) and N 6-dimethyladenosine containing trinucleoside diphosphate analogs.
Topics: Alanine; Anti-Bacterial Agents; Glutamates; Glycine; In Vitro Techniques; Lysine; Nucleotides; Proline; Ribosomes; RNA, Transfer; Serine; Threonine | 1965 |
The determination of amino acids in 0.1 ml. of blood plasma.
Topics: Alanine; Amino Acids; Arginine; Blood Chemical Analysis; Chemistry, Clinical; Chromatography, Gel; Chromatography, Paper; Colorimetry; Densitometry; Glutamine; Glycine; Humans; In Vitro Techniques; Lysine; Microchemistry; Serine; Taurine; Threonine; Valine | 1966 |
Amino acids in seven species of cestodes.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cestoda; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Nitrogen; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Isolation of amino acyl oligonucleotides from T-1 ribonuclease digests of soluble ribonucleic acid charged with serine, glycine, threonine, and alanine.
Topics: Alanine; Chromatography, Ion Exchange; Electrophoresis; Glycine; Nucleotides; Ribonucleases; RNA, Transfer; Saccharomyces; Serine; Threonine | 1966 |
Polyamide layer chromatography of DNP-amino acids.
Topics: Alanine; Amides; Arginine; Aspartic Acid; Chromatography; Dinitrophenols; Glutamates; Glycine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
Water relations of Salmonella oranienburg; stimulation of respiration by amino acids.
Topics: Alanine; Asparagine; Aspartic Acid; Carbon Isotopes; Culture Media; Cysteine; Glucose; Glutamine; Glycine; Methionine; Oxygen Consumption; Proline; Salmonella; Serine; Threonine; Water | 1966 |
Amino acid transport in the goldfish intestine.
Topics: Alanine; Animals; Biological Transport, Active; Fishes; Histidine; Intestinal Mucosa; Leucine; Methionine; Phenylalanine; Serine; Threonine; Valine | 1966 |
Gas chromatographic separation of DNP amino acids and its application to the analysis of serum amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Cholesterol; Chromatography, Gas; Glutamates; Glycine; Hydroxyproline; Indicators and Reagents; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Valine | 1966 |
Nuclear histones and early embryogenesis of the chick.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Cell Division; Cell Nucleus; Chick Embryo; Electrophoresis; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Analysis of N-methylamino acids by automatic amino acid analyzer and gas-liquid chromatography.
Topics: Alanine; Anti-Bacterial Agents; Arginine; Aspartic Acid; Autoanalysis; Chromatography, Gas; Cysteine; Cystine; Glutamates; Glycine; Indicators and Reagents; Isoleucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1966 |
[Composition of the amino acid pool of Neurospora in deficiency of growth substance].
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Biotin; Choline; Chromatography, Ion Exchange; Culture Media; Glutamates; Glycine; Growth Inhibitors; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Pyridoxine; Riboflavin; Serine; Threonine; Tyrosine; Valine | 1966 |
[On the structure of protamine. VII. On the effect of the age of the fishes on the composition of their protamine].
Topics: Age Factors; Alanine; Amino Acids; Animals; Arginine; Fishes; Glutamates; Proline; Protamines; Serine; Threonine; Tyrosine; Valine | 1966 |
[Amino acid content in parts of the brain in hyperoxia].
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Brain; Cerebellum; Cystine; Glutamates; Glutamine; Medulla Oblongata; Mesencephalon; Optic Lobe, Nonmammalian; Oxygen; Rabbits; Spasm; Threonine | 1966 |
[Isolation and characteristics of the new antibacterial antibiotic mutabilicin (21-31)].
Topics: Actinomyces; Alanine; Amino Acids; Anti-Bacterial Agents; Chromatography, Paper; Cystine; Glycine; Infrared Rays; Peptides; Spectrophotometry; Threonine; Tyrosine; Ultraviolet Rays; Valine | 1966 |
[Quantitative changes in amino acids in grapes at different ripening stages].
Topics: Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Chromatography, Ion Exchange; Fruit; Glutamates; Serine; Threonine; Valine | 1966 |
[Chromatographic investigation of free amino acids of the heart, kidneys and brain in experimental myocarditis].
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Brain; Chromatography, Paper; Cystine; Glutamine; Glycine; Histidine; Kidney; Lysine; Methionine; Myocarditis; Myocardium; Phenylalanine; Rabbits; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
Free amino acids of human foetal and adult liver.
Topics: Adult; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Cystine; Female; Fetus; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1966 |
Renal metabolism of alanine.
Topics: Alanine; Ammonia; Animals; Dogs; Glomerular Filtration Rate; Glutamates; Glutamine; Glycine; Ketoglutaric Acids; Kidney; Kidney Tubules; Oxidation-Reduction; Pyruvates; Serine; Threonine | 1967 |
Free amino acids in gamma-irradiated carrots.
Topics: Acetates; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Carbon Isotopes; Glutamates; Leucine; Methionine; Plants, Edible; Proline; Radiation Effects; Serine; Threonine; Tyrosine | 1967 |
Further studies of amino acid transport by embryonic chick bone.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Bone and Bones; Chick Embryo; Dactinomycin; Ethylmaleimide; Glycine; In Vitro Techniques; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Comparison of the carbohydrate and amino acid composition of bovine, ovine and human luteinizing hormone.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cattle; Galactose; Glucosamine; Glutamates; Hexosamines; Hexoses; Humans; In Vitro Techniques; Luteinizing Hormone; Lysine; Mannose; Neuraminic Acids; Proline; Serine; Sheep; Threonine; Valine | 1967 |
Glutamic-pyruvic transaminase and gluconeogenesis in liver slices: a comparison of the effects of cortisol injection with treatment in vitro.
Topics: Alanine; Alanine Transaminase; Animals; Gluconeogenesis; Glutamates; Hydrocortisone; In Vitro Techniques; Liver; Pyruvates; Rats; Threonine | 1967 |
Effects of cortisol and 19-nortestosterone on the free amino acid pools and amino acid uptake of cultured cells.
Topics: Alanine; Amino Acids; Aspartic Acid; Biological Transport; Carbon Isotopes; Culture Techniques; Glycine; HeLa Cells; Hydrocortisone; Nandrolone; Neoplasms, Experimental; Serine; Threonine | 1967 |
The recovery of amino acids from acid hydrolysates of whole urine from patients with thermal burns.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Burns; Creatine; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1967 |
Urinary amino acids of rats receiving high sugar diets.
Topics: Alanine; Alcohols; Amino Acids; Animals; Arabinose; Ascorbic Acid; Asparagine; Aspartic Acid; Dietary Carbohydrates; Female; Galactose; Glucose; Glutamates; Glycine; Inositol; Intestines; Neomycin; Rats; Ribose; Serine; Taurine; Threonine; Xylitol; Xylose | 1967 |
Electron microscopic and biochemical characterization of collagen in blattarian insects.
Topics: Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Collagen; Connective Tissue Cells; Cysteine; Cystine; Female; Glutamates; Glycine; Histidine; Histocytochemistry; Hydroxyproline; Insecta; Isoleucine; Leucine; Lysine; Male; Methionine; Microscopy, Electron; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1967 |
Rapid short-column chromatography of amino acids. A method for blood and urine specimens in the diagnosis and treatment of metabolic disease.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Aminobutyrates; Autoanalysis; Buffers; Chromatography, Ion Exchange; Citrates; Cysteine; Cystine; Glutamates; Glutamine; Glycine; Humans; Hydrogen-Ion Concentration; Hydroxyproline; Isoleucine; Phenylalanine; Proline; Sarcosine; Serine; Threonine; Tyrosine; Valine | 1967 |
Concentrations of free glucogenic amino acids in livers of rats subjected to various metabolic stresses.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Diabetes Mellitus, Experimental; Gluconeogenesis; Glutamates; Glutamine; Hypoxia; Insulin; Liver; Male; Phlorhizin; Rats; Serine; Starvation; Threonine; Transaminases | 1967 |
Gluconeogenesis from amino acids in neonatal rat liver.
Topics: Alanine; Alanine Transaminase; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartate Aminotransferases; Aspartic Acid; Gluconeogenesis; Glutamates; Glycine; Histidine; In Vitro Techniques; Leucine; Liver; Liver Glycogen; Phenylalanine; Proline; Rats; Serine; Spectrophotometry; Threonine; Tyrosine; Valine | 1967 |
Chromatographic analysis of free amino acids of gastric juice in patients with cancer and other stomach diseases.
Topics: Adult; Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Cystine; Duodenal Ulcer; Female; Gastric Juice; Glutamates; Histidine; Humans; Leucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Polyps; Stomach Diseases; Stomach Neoplasms; Stomach Ulcer; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
The influence of nitrogenous compounds on growth of Pythium species.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Cysteine; Fungi; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Nitrates; Nitrites; Nitrogen; Peptones; Quaternary Ammonium Compounds; Serine; Succinates; Threonine; Yeast, Dried | 1967 |
The effect of progesterone on the concentration of plasma amino acids in man.
Topics: Acromegaly; Alanine; Amino Acids; Arginine; Citrulline; Cystine; Fasting; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Progesterone; Proline; Proteins; Threonine; Tyrosine; Valine | 1967 |
Free amino acids, ammonia and urea concentrations in the blood plasma of starved lambs.
Topics: Age Factors; Alanine; Amino Acids; Ammonia; Analysis of Variance; Animals; Animals, Newborn; Body Weight; Glutamates; Isoleucine; Leucine; Lysine; Sheep; Starvation; Threonine; Urea; Valine | 1967 |
Effect of amino acids on zinc-65 incorporation by Ehrlich ascites tumor cells in vitro.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Female; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Lysine; Methionine; Mice; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Zinc; Zinc Isotopes | 1967 |
Structure-activity relationships of somatostatin analogs in the rabbit ileum and the rat colon.
Topics: Alanine; Amino Acid Sequence; Animals; Biological Transport; Chlorides; Colon; Glycine; Ileum; Male; Phenylalanine; Protein Conformation; Rabbits; Rats; Rats, Inbred Strains; Somatostatin; Threonine | 1983 |
Study of the relationship between free amino acids and cataract in human lenses.
Topics: Adult; Aged; Alanine; Amino Acids; Cataract; Glutamates; Glutamic Acid; Glycine; Humans; Lens, Crystalline; Leucine; Middle Aged; Serine; Threonine | 1984 |
Symmetrical distribution of amino acid neurotransmitters in the right and left cerebral cortex of the rat.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Glycine; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Threonine; Tissue Distribution | 1984 |
Hb F-Calluna or alpha 2 gamma 2(12 Thr replaced by Arg; 75Ile; 136Ala) in a Caucasian baby.
Topics: Alanine; Amino Acid Sequence; Arginine; Fetal Blood; Fetal Hemoglobin; Hemoglobins, Abnormal; Humans; Infant, Newborn; Isoleucine; Male; Threonine | 1983 |
Plasminogen Tochigi: inactive plasmin resulting from replacement of alanine-600 by threonine in the active site.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Fibrinolysin; Humans; Peptide Fragments; Plasminogen; Structure-Activity Relationship; Threonine | 1982 |
Control of hepatic utilization of serine, glycine and threonine in fed and starved rats.
Topics: Alanine; Alanine Transaminase; Animals; Dietary Carbohydrates; Dietary Proteins; Gluconeogenesis; Glycine; L-Serine Dehydratase; Lactates; Lactic Acid; Liver; Male; Rats; Serine; Starvation; Threonine | 1983 |
Biochemical studies of olfaction: binding specificity of odorants to a cilia preparation from rainbow trout olfactory rosettes.
Topics: Alanine; Animals; Binding, Competitive; Central Nervous System; Cilia; Kinetics; Odorants; Olfactory Pathways; Sensory Receptor Cells; Serine; Smell; Threonine; Tritium; Trout | 1983 |
Threonine uptake in Trypanosoma brucei.
Topics: Alanine; Animals; Biological Transport, Active; Kinetics; Oxygen Consumption; Rats; Threonine; Trypanosoma brucei brucei; Trypanosomiasis, African | 1984 |
Neutral amino acid transport and in vitro aging.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport; Cell Line; Cell Survival; Culture Media; Fibroblasts; Humans; Kinetics; Phenylalanine; Serine; Threonine | 1984 |
Gluconeogenesis from threonine in normal and diabetic rats.
Topics: Alanine; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Gluconeogenesis; Kinetics; Male; Rats; Rats, Inbred Strains; Starvation; Threonine | 1984 |
Plasma amino acids in 3/sec spike-wave epilepsy.
Topics: Adolescent; Adult; Alanine; Amino Acids; Aspartic Acid; Child; Child, Preschool; Epilepsy; Female; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Male; Methionine; Middle Aged; Phenylalanine; Serine; Taurine; Threonine; Tyrosine; Valine | 1980 |
Localization of a cross-link donor site in the alpha-chain of human fibrin.
Topics: Alanine; Amino Acid Sequence; Cross-Linking Reagents; Cyanogen Bromide; Cysteine; Fibrin; Fibrinogen; Lysine; Peptides; Threonine; Valine | 1980 |
Amino acid transport via the red cell anion transport system.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Alanine; Amino Acids; Biological Transport; Carrier Proteins; Cysteine; Depression, Chemical; Erythrocytes; Glycine; Humans; In Vitro Techniques; Proline; Serine; Threonine; Valine | 1981 |
A kirromycin resistant elongation factor EF-Tu from Escherichia coli contains a threonine instead of an alanine residue in position 375.
Topics: Alanine; Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Microbial; Escherichia coli; Peptide Elongation Factor Tu; Peptide Elongation Factors; Pyridones; Structure-Activity Relationship; Threonine | 1981 |
Loss of amino acids during hemodialysis: effect of oral essential amino acid supplementation.
Topics: Administration, Oral; Alanine; Amino Acids; Amino Acids, Essential; Humans; Male; Methionine; Renal Dialysis; Threonine | 1981 |
pH and temperature effects on the molecular conformation of the porcine pancreatic secretory trypsin inhibitor as detected by hydrogen-1 nuclear magnetic resonance.
Topics: Alanine; Animals; Cattle; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Magnetic Resonance Spectroscopy; Protein Conformation; Structure-Activity Relationship; Temperature; Threonine; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Valine | 1982 |
Isolation and characterization of a Pseudomonas aeruginosa PAO mutant defective in the structural gene for the LIVAT-binding protein.
Topics: Alanine; Bacterial Proteins; Biological Transport; Carrier Proteins; Chromosome Mapping; Chromosomes, Bacterial; Genes; Genes, Bacterial; Isoleucine; Leucine; Pseudomonas aeruginosa; Threonine; Valine | 1982 |
Detection of Hb-Papio B, a silent mutation of the baboon beta chain, by high performance liquid chromatography. Improved procedures for the separation of globin chains by HPLC.
Topics: Alanine; Amines; Amino Acids; Animals; Chromatography, High Pressure Liquid; Female; Globins; Hemoglobins, Abnormal; Humans; Mutation; Papio; Threonine | 1982 |
Replacement of conserved threonines by alanine residues in high mobility group protein HMG-I(Y): effect on DNA binding affinity.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Binding, Competitive; Bisbenzimidazole; Cloning, Molecular; Computer Simulation; Conserved Sequence; DNA; High Mobility Group Proteins; HMGA1a Protein; Humans; Kinetics; Mammals; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Osmolar Concentration; Peptides; Phosphorylation; Point Mutation; Protein Conformation; Recombinant Proteins; Threonine | 1995 |
Phosphorylation on threonine-18 of the regulatory light chain dissociates the ATPase and motor properties of smooth muscle myosin II.
Topics: Actins; Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Animals; Bacteria; Base Sequence; Chickens; Cloning, Molecular; DNA; Enzyme Activation; Molecular Sequence Data; Muscle, Smooth; Mutagenesis, Site-Directed; Myosin-Light-Chain Kinase; Myosins; Phosphorylation; Sequence Homology, Amino Acid; Threonine; Xenopus | 1995 |
Long timestep dynamics of peptides by the dynamics driver approach.
Topics: Alanine; Chemical Phenomena; Chemistry, Physical; Computer Simulation; Dipeptides; Energy Transfer; Freezing; Glycine; Mathematics; Models, Chemical; Peptides; Physical Phenomena; Physics; Protein Conformation; Protein Folding; Temperature; Threonine; Valine | 1995 |
Inhibitory and excitatory amino acids in cerebrospinal fluid of neurolathyrism patients, a highly prevalent motorneurone disease.
Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Eating; Excitatory Amino Acids; Fabaceae; Glutamic Acid; Glycine; Humans; Isoleucine; Middle Aged; Motor Neuron Disease; Neurotoxins; Plants, Medicinal; Taurine; Threonine | 1995 |
Functional distinction of two regions of human interleukin 6 important for signal transduction via gp130.
Topics: Alanine; Antibodies, Monoclonal; Antigens, CD; Gene Library; Genetic Testing; Glutamine; Histidine; Humans; Interleukin-6; Multiple Myeloma; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Receptors, Interleukin; Receptors, Interleukin-6; Signal Transduction; Threonine; Tumor Cells, Cultured | 1995 |
[A new point mutation in the mitochondrial gene ND1, detected in a patient with type II diabetes].
Topics: Alanine; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Humans; NADH Dehydrogenase; Optic Atrophies, Hereditary; Point Mutation; Threonine | 1995 |
A single amino acid exchange abolishes dimerization of the androgen receptor and causes Reifenstein syndrome.
Topics: Alanine; Base Sequence; Binding Sites; Cell Line; DNA; Humans; Macromolecular Substances; Molecular Sequence Data; Mutation; Protein Conformation; Receptors, Androgen; Structure-Activity Relationship; Syndrome; Threonine | 1995 |
Frequency of mutations of insulin receptor gene in Japanese patients with NIDDM.
Topics: Adult; Aged; Alanine; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Chlorocebus aethiops; Cysteine; Diabetes Mellitus, Type 2; DNA; DNA Primers; Exons; Female; Genetic Linkage; Humans; Insulin; Japan; Kinetics; Macromolecular Substances; Male; Middle Aged; Molecular Sequence Data; Pedigree; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Polymerase Chain Reaction; Receptor, Insulin; Recombinant Proteins; Threonine; Transfection; Tyrosine | 1995 |
Effects of different amino acids on the electrical characteristics of pharmaceutical polymers.
Topics: Alanine; Amino Acids; Chemistry, Pharmaceutical; Electrophoresis; Glutamic Acid; Glycine; Hydrogen-Ion Concentration; Lysine; Polymers; Threonine | 1995 |
Mutational analysis of the putative substrate-binding site of 3C proteinase of coxsackievirus B3.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Conserved Sequence; DNA Primers; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enterovirus B, Human; Escherichia coli; Glycine; Histidine; Molecular Sequence Data; Mutation; Sequence Alignment; Serine; Threonine | 1995 |
The mushroom-inducing gene Frt1 of Schizophyllum commune encodes a putative nucleotide-binding protein.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Basidiomycota; Carrier Proteins; DNA Primers; Fungal Proteins; Genes, Fungal; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleotides; Protein Structure, Secondary; Recombinant Proteins; Schizophyllum; Threonine | 1995 |
Acceleration of GABA-dependent desensitization by mutating threonine 266 to alanine of the alpha 6 subunit of rat GABAA receptors.
Topics: Alanine; Animals; Cells, Cultured; Chloride Channels; gamma-Aminobutyric Acid; Kidney; Membrane Potentials; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Point Mutation; Rats; Receptors, GABA-A; Threonine | 1995 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
Glutamine transport and enzymatic activities involved in glutaminolysis in human platelets.
Topics: Alanine; Aspartate Aminotransferases; Biological Transport; Blood Platelets; Glutamate Dehydrogenase; Glutaminase; Glutamine; Humans; Hydrolysis; Membranes; Sodium; Threonine; Transaminases | 1995 |
An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance.
Topics: Adult; Alanine; Alleles; Arizona; Base Sequence; Calorimetry; Carrier Proteins; Chromosomes, Human, Pair 4; Diabetes Mellitus, Type 2; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Female; Gene Frequency; Glucose; Glucose Clamp Technique; Humans; Indians, North American; Insulin Resistance; Male; Models, Molecular; Molecular Sequence Data; Neoplasm Proteins; Oxidation-Reduction; Point Mutation; Polymerase Chain Reaction; Prospective Studies; Risk Factors; Threonine; Tumor Suppressor Proteins | 1995 |
Role of Thr-252 in cytochrome P450cam: a study with unnatural amino acid mutagenesis.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Camphor 5-Monooxygenase; Carbon Monoxide; Cytochrome P-450 Enzyme System; DNA Primers; Mixed Function Oxygenases; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; NADH, NADPH Oxidoreductases; Point Mutation; Polymerase Chain Reaction; Pseudomonas putida; Recombinant Proteins; RNA, Transfer, Amino Acyl; Spectrophotometry; Threonine; Valine | 1995 |
Different sites of acivicin binding and inactivation of gamma-glutamyl transpeptidases.
Topics: Alanine; Amino Acid Sequence; Animals; Antimetabolites; Base Sequence; Binding Sites; Cloning, Molecular; DNA Primers; gamma-Glutamyltransferase; Humans; Hydroxylamine; Hydroxylamines; Isoxazoles; Kidney; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Point Mutation; Rats; Recombinant Proteins; Restriction Mapping; Serine; Swine; Threonine | 1995 |
Acquisition of azide-resistance by elevated SecA ATPase activity confers azide-resistance upon cell growth and protein translocation in Bacillus subtilis.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Azides; Bacillus subtilis; Bacterial Proteins; Base Sequence; Biological Transport; Cell Division; DNA Primers; Drug Resistance, Microbial; Escherichia coli Proteins; Isoleucine; Kinetics; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Polymerase Chain Reaction; Restriction Mapping; SEC Translocation Channels; SecA Proteins; Sodium Azide; Threonine | 1995 |
Effects of substitution of Thr63 by alanine on the structure and function of Lactobacillus casei dihydrofolate reductase.
Topics: Alanine; Kinetics; Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; Methotrexate; Models, Molecular; Mutagenesis, Site-Directed; NADP; Solutions; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thermodynamics; Threonine | 1994 |
Histidine ammonia-lyase mutant S143C is posttranslationally converted into fully active wild-type enzyme. Evidence for serine 143 to be the precursor of active site dehydroalanine.
Topics: Alanine; Base Sequence; Cysteine; Histidine Ammonia-Lyase; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxygen; Protein Precursors; Protein Processing, Post-Translational; Pseudomonas putida; Recombinant Proteins; Serine; Structure-Activity Relationship; Sulfhydryl Compounds; Threonine | 1994 |
Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid.
Topics: Adenoma; Alanine; Amino Acid Sequence; Base Sequence; Cell Line; Codon; Cyclic AMP; Gene Expression; Humans; Isoleucine; Molecular Sequence Data; Mutation; Receptors, Thyrotropin; Structure-Activity Relationship; Threonine; Thyroid Neoplasms; Transfection; Valine | 1994 |
Primary structure of maize chloroplast adenylate kinase.
Topics: Adenylate Kinase; Alanine; Amino Acid Sequence; Chloroplasts; Electrophoresis, Polyacrylamide Gel; Enterobacteriaceae; Escherichia coli; Isoelectric Point; Mass Spectrometry; Molecular Sequence Data; Molecular Weight; Sequence Alignment; Substrate Specificity; Threonine; Zea mays | 1994 |
Threonine-497 is a critical site for permissive activation of protein kinase C alpha.
Topics: Alanine; Animals; Base Sequence; Binding Sites; Catalysis; Cattle; Cell Line; DNA, Complementary; Enzyme Activation; Gene Expression; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinase C; Recombinant Proteins; Structure-Activity Relationship; Threonine; Transfection | 1994 |
An Ala/Thr variation in the coding region of the human cystatin C gene (CST3) detected as a SstII polymorphism.
Topics: Alanine; Alleles; Base Sequence; Cerebral Amyloid Angiopathy; Chromosomes, Human, Pair 20; Cystatin C; Cystatins; Deoxyribonucleases, Type II Site-Specific; Gene Frequency; Humans; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Threonine | 1993 |
H-ras mutations in human pituitary carcinoma metastases.
Topics: Adenoma; Alanine; Arginine; Base Sequence; DNA, Neoplasm; Exons; Genes, p53; Genes, ras; Glycine; Humans; Molecular Sequence Data; Mutation; Neoplasm Metastasis; Pituitary Neoplasms; Polymerase Chain Reaction; Threonine | 1994 |
Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme.
Topics: Alanine; Amino Acid Sequence; Bacteriophage T4; Calorimetry; Circular Dichroism; Enzyme Stability; Models, Molecular; Muramidase; Mutagenesis, Site-Directed; Point Mutation; Protein Structure, Secondary; Recombinant Proteins; Serine; Threonine; Valine | 1993 |
Study of wild type and genetically modified reaction centers from Rhodobacter capsulatus: structural comparison with Rhodopseudomonas viridis and Rhodobacter sphaeroides.
Topics: Alanine; Amino Acid Sequence; Benzoquinones; Isoleucine; Kinetics; Light-Harvesting Protein Complexes; Mathematics; Mutagenesis, Site-Directed; Phenanthrolines; Photosynthetic Reaction Center Complex Proteins; Rhodobacter capsulatus; Rhodobacter sphaeroides; Rhodopseudomonas; Serine; Threonine | 1993 |
Effects of antiandrogens on transformation and transcription activation of wild-type and mutated (LNCaP) androgen receptors.
Topics: Adenocarcinoma; Alanine; Amino Acid Sequence; Androgen Antagonists; Anilides; Animals; Blotting, Western; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; Cyproterone Acetate; Dose-Response Relationship, Drug; Flutamide; Humans; Male; Metribolone; Mutagenesis, Site-Directed; Nitriles; Point Mutation; Prostatic Neoplasms; Receptors, Androgen; Recombinant Proteins; Threonine; Tosyl Compounds; Transcription, Genetic; Transfection; Transformation, Genetic; Tumor Cells, Cultured | 1993 |
Androgen receptor gene mutations in human prostate cancer.
Topics: Adenocarcinoma; Alanine; Amino Acid Sequence; Base Sequence; DNA Primers; DNA-Binding Proteins; DNA, Neoplasm; Exons; Genetic Variation; Histidine; Humans; Leucine; Male; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Prostatic Neoplasms; Receptors, Androgen; Threonine | 1993 |
Threonine for alanine substitution at position 109 of transthyretin differentially alters human transthyretin's affinity for iodothyronines.
Topics: Alanine; Amino Acid Sequence; Binding, Competitive; Escherichia coli; Flavonoids; Humans; Point Mutation; Prealbumin; Recombinant Proteins; Stereoisomerism; Threonine; Thyroxine; Triiodothyronine | 1994 |
Type 2 (non-insulin-dependent) diabetes mellitus associated with a mutation of the glucokinase gene in a Japanese family.
Topics: Adolescent; Adult; Alanine; Amino Acid Sequence; Base Sequence; Blood Glucose; Codon; Diabetes Mellitus, Type 2; Dinucleoside Phosphates; Exons; Female; Glucokinase; Glucose Tolerance Test; Humans; Insulin; Male; Middle Aged; Molecular Sequence Data; Pedigree; Point Mutation; Polymerase Chain Reaction; Threonine | 1993 |
Lecithin:cholesterol acyltransferase deficiency: identification of a causative gene mutation and a co-inherited protein polymorphism.
Topics: Alanine; Amino Acid Sequence; Arginine; Base Sequence; Cystine; Humans; Lecithin Cholesterol Acyltransferase Deficiency; Lipoproteins; Molecular Sequence Data; Mutation; Phosphatidylcholine-Sterol O-Acyltransferase; Polymorphism, Genetic; Threonine | 1993 |
The Ala-161-->Thr substitution in Escherichia coli alkaline phosphatase does not result in loss of enzymatic activity although the homologous mutation in humans causes hypophosphatasia.
Topics: Alanine; Alkaline Phosphatase; Amino Acid Sequence; Bone and Bones; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Humans; Hypophosphatasia; Isoenzymes; Kidney; Kinetics; Liver; Mutagenesis, Site-Directed; Point Mutation; Recombinant Proteins; Threonine | 1993 |
A point mutation of alanine 163 to threonine is responsible for the defective secretion of high molecular weight kininogen by the liver of brown Norway Katholiek rats.
Topics: Alanine; Animals; Base Sequence; Blotting, Northern; Cell Line; Cloning, Molecular; DNA; DNA Probes; Kininogens; Liver; Molecular Sequence Data; Plasmids; Point Mutation; Rats; Rats, Inbred BN; Threonine; Transfection | 1993 |
A hinge region mutation in C1-inhibitor (Ala436-->Thr) results in nonsubstrate-like behavior and in polymerization of the molecule.
Topics: Alanine; Amino Acid Sequence; Animals; Cell Line; Centrifugation, Density Gradient; Chromatography, Gel; Cloning, Molecular; Complement C1 Inactivator Proteins; Drug Stability; Electrophoresis, Polyacrylamide Gel; Humans; Microscopy, Electron; Point Mutation; Protein Denaturation; Thermodynamics; Threonine; Transfection | 1993 |
Mutation of the cyclin-dependent kinase phosphorylation site in simian virus 40 (SV40) large T antigen specifically blocks SV40 origin DNA unwinding.
Topics: Alanine; Amino Acid Sequence; Animals; Antigens, Polyomavirus Transforming; Baculoviridae; Binding Sites; Cyclins; DNA Helicases; DNA Replication; DNA, Viral; Humans; Kinetics; Microscopy, Electron; Moths; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinases; Simian virus 40; Threonine; Transfection | 1993 |
Molecular dynamics study of the stability of staphylococcal nuclease mutants: component analysis of the free energy difference of denaturation.
Topics: Alanine; Amino Acid Sequence; Computer Simulation; Enzyme Stability; Glycine; Micrococcal Nuclease; Models, Molecular; Molecular Sequence Data; Mutation; Protein Denaturation; Thermodynamics; Threonine; Valine | 1993 |
Hierarchal constitutive phosphorylation of the vesicular stomatitis virus P protein and lack of effect on P1 to P2 conversion.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Cell Line; DNA-Directed RNA Polymerases; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Phosphates; Phosphoproteins; Phosphorylation; RNA-Dependent RNA Polymerase; Serine; Threonine; Transfection; Vesicular stomatitis Indiana virus; Vesiculovirus; Viral Proteins; Viral Structural Proteins | 1995 |
Site-directed mutagenesis of Thermus thermophilus EF-Tu: the substitution of threonine-62 by serine or alanine.
Topics: Alanine; Base Sequence; Binding Sites; DNA Primers; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; RNA, Transfer, Amino Acyl; Serine; Thermus thermophilus; Threonine | 1995 |
Substitution of alanine543 with a threonine residue at the carboxy terminal end of the beta-chain is associated with thermolabile hexosaminidase B in a Jewish family of Oriental ancestry.
Topics: Alanine; Base Sequence; beta-N-Acetylhexosaminidases; Chromatography, Ion Exchange; Exons; Female; Fibroblasts; Hexosaminidase B; Hot Temperature; Humans; Iran; Jews; Male; Molecular Sequence Data; Pedigree; Protein Denaturation; Threonine | 1995 |
Requirements for calcium and calmodulin in the calmodulin kinase activation cascade.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Brain; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Line; Cloning, Molecular; DNA Primers; Enzyme Activation; Escherichia coli; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphorylation; Point Mutation; Polymerase Chain Reaction; Rats; Recombinant Proteins; Sequence Tagged Sites; Spodoptera; Threonine; Transcriptional Activation; Transfection | 1996 |
Thr353, located within the COOH-terminal tail of the delta opiate receptor, is involved in receptor down-regulation.
Topics: Alanine; Amino Acid Sequence; Animals; Cell Membrane; CHO Cells; Clone Cells; Cricetinae; Diprenorphine; Down-Regulation; Enkephalin, Leucine-2-Alanine; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Receptors, Opioid, delta; Recombinant Proteins; Sequence Tagged Sites; Threonine; Transfection | 1996 |
Is the NAD(P)H:flavin oxidoreductase from Escherichia coli a member of the ferredoxin-NADP+ reductase family?. Evidence for the catalytic role of serine 49 residue.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Catalysis; DNA Primers; Escherichia coli; Flavins; FMN Reductase; Hydroxyl Radical; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NADH, NADPH Oxidoreductases; NADP; Sequence Alignment; Serine; Threonine | 1996 |
A novel missense mutation in two families with congenital plasminogen deficiency: identification of an Ala675 to Thr675 substitution.
Topics: Adolescent; Adult; Alanine; Base Sequence; Child; Deoxyribonucleases, Type II Site-Specific; Female; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation; Pedigree; Plasminogen; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Threonine | 1996 |
Significance of Thr182 in the nucleotide-exchange and GTP-hydrolysis reactions of the alpha subunit of GTP-binding protein Gi2.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Escherichia coli; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanosine Triphosphate; Hydrolysis; Magnesium; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleotides; Peptide Fragments; Proto-Oncogene Proteins; Rats; Recombinant Proteins; Threonine | 1995 |
1H-NMR and 13C-NMR investigation of complexes of Mn2+ with ocytocin analogues in (2H6)dimethylsulfoxide.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Carbon Isotopes; Cysteine; Deuterium; Dimethyl Sulfoxide; Glutamine; Hydrogen; Magnetic Resonance Spectroscopy; Manganese; Models, Molecular; Molecular Sequence Data; Oxytocin; Proline; Protein Binding; Protein Conformation; Sarcosine; Sulfhydryl Compounds; Thermodynamics; Threonine | 1996 |
Trace analysis in chiral separation of selected amino enantiomers.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Fluorometry; Leucine; Perchlorates; Phenylalanine; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism; Threonine | 1996 |
Alanine substitution for Thr268 and Asp269 of soluble ciliary neurotrophic factor (CNTF) receptor alpha component defines a specific antagonist for the CNTF response.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Binding, Competitive; Cell Division; Cell Line; Ciliary Neurotrophic Factor; Haptoglobins; Liver Neoplasms, Experimental; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Phosphorylation; Rats; Receptor, Ciliary Neurotrophic Factor; Receptors, Nerve Growth Factor; Sequence Alignment; Solubility; Threonine; Tyrosine | 1996 |
Genetic diagnosis of dysplasminogenemia: detection of an Ala601-Thr mutation in 118 out of 125 families and identification of a new Asp676-Asn mutation.
Topics: Adult; Alanine; Asparagine; Aspartic Acid; Female; Genetic Testing; Humans; Male; Mutation; Phenylalanine; Plasminogen; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Sequence Analysis, DNA; Structure-Activity Relationship; Threonine; Thrombosis | 1996 |
Structure-function relationships among wild-type variants of Staphylococcus aureus beta-lactamase: importance of amino acids 128 and 216.
Topics: Alanine; Asparagine; beta-Lactamases; Crystallography, X-Ray; Gene Expression; Genetic Variation; Kinetics; Serine; Staphylococcus aureus; Structure-Activity Relationship; Threonine | 1996 |
Phosphorylation of protein kinase Cdelta (PKCdelta) at threonine 505 is not a prerequisite for enzymatic activity. Expression of rat PKCdelta and an alanine 505 mutant in bacteria in a functional form.
Topics: Alanine; Animals; Baculoviridae; Enzyme Inhibitors; Escherichia coli; Isoenzymes; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Structure, Tertiary; Rats; Recombinant Proteins; Spodoptera; Structure-Activity Relationship; Threonine | 1997 |
Serine319 and 321 are functional in isocitrate lyase from Escherichia coli.
Topics: Alanine; Asparagine; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression Regulation, Bacterial; Glycine; Histidine; Isocitrate Lyase; Isocitrates; Kinetics; Magnesium; Mutagenesis, Site-Directed; Oligonucleotides; Plasmids; Proline; Sequence Alignment; Serine; Threonine | 1997 |
Expression and regulation of mutant forms of cardiac TnI in a reconstituted actomyosin system: role of kinase dependent phosphorylation.
Topics: Actomyosin; Alanine; Animals; Calcium; Cloning, Molecular; Cyclic AMP-Dependent Protein Kinases; Dogs; Kinetics; Muscle, Skeletal; Mutagenesis, Site-Directed; Myocardium; Myosins; Phosphorylation; Point Mutation; Protein Kinase C; Recombinant Proteins; Threonine; Troponin I | 1997 |
Rhodopsin phosphorylation sites and their role in arrestin binding.
Topics: Alanine; Amino Acid Sequence; Animals; Arrestin; Binding Sites; Cattle; Cell Line; Eye Proteins; G-Protein-Coupled Receptor Kinase 1; Humans; Kinetics; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Protein Kinases; Protein Structure, Secondary; Recombinant Proteins; Rhodopsin; Serine; Threonine; Transfection | 1997 |
Threonine allele in codon 54 of the fatty acid binding protein 2 gene does not modify the fatty acid composition of serum lipids in obese subjects.
Topics: Adult; Alanine; Alleles; Carrier Proteins; Codon; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Fatty Acids, Nonesterified; Female; Finland; Heterozygote; Homozygote; Humans; Lipids; Male; Middle Aged; Myelin P2 Protein; Neoplasm Proteins; Obesity; Threonine; Triglycerides; Tumor Suppressor Proteins | 1997 |
[Directed mutagenesis of human recombinant receptors of vasoactive intestinal peptide of VIP1 and VIP2 type. Difference in structure-activity relationship].
Topics: Alanine; Binding Sites; Glutamic Acid; Humans; Isoleucine; Mutagenesis, Site-Directed; Receptors, Vasoactive Intestinal Peptide; Structure-Activity Relationship; Threonine | 1997 |
Protein kinase A activation of the surfactant protein B gene is mediated by phosphorylation of thyroid transcription factor 1.
Topics: Alanine; Catalysis; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Epithelium; HeLa Cells; Hepatocyte Nuclear Factor 3-alpha; Hepatocyte Nuclear Factor 3-beta; Homeodomain Proteins; Humans; Lung; Mutation; Nuclear Proteins; Phosphorylation; Promoter Regions, Genetic; Protein Conformation; Protein Kinase C; Proteolipids; Pulmonary Surfactants; Threonine; Thyroid Nuclear Factor 1; Transcription Factors; Transfection; Tumor Cells, Cultured | 1997 |
A refined model for the somatostatin pharmacophore: conformational analysis of lanthionine-sandostatin analogs.
Topics: Alanine; Amino Acid Sequence; Animals; Calorimetry; Humans; Isomerism; Magnetic Resonance Spectroscopy; Models, Molecular; Octreotide; Peptides, Cyclic; Protein Structure, Secondary; Receptors, Somatostatin; Structure-Activity Relationship; Sulfides; Threonine | 1997 |
Association between Ala54Thr substitution of the fatty acid-binding protein 2 gene with insulin resistance and intra-abdominal fat thickness in Japanese men.
Topics: Abdomen; Adipose Tissue; Alanine; Body Mass Index; Carrier Proteins; DNA; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Heterozygote; Homozygote; Humans; Insulin Resistance; Japan; Leukocytes; Male; Middle Aged; Myelin P2 Protein; Neoplasm Proteins; Point Mutation; Polymorphism, Genetic; Threonine; Tumor Suppressor Proteins | 1997 |
Molecular structures of the S124A, S124T, and S124V site-directed mutants of UDP-galactose 4-epimerase from Escherichia coli.
Topics: Alanine; Binding Sites; Crystallography, X-Ray; Escherichia coli; Glucose; Macromolecular Substances; Mutagenesis, Site-Directed; NAD; Serine; Substrate Specificity; Threonine; UDPglucose 4-Epimerase; Uridine Diphosphate; Valine | 1997 |
Mutations in the C-terminal domain of Sonic Hedgehog cause holoprosencephaly.
Topics: Alanine; Amino Acid Sequence; Animals; Cell Line, Transformed; DNA Mutational Analysis; Exons; Female; Genes, Dominant; Glutamic Acid; Glycine; Hedgehog Proteins; Holoprosencephaly; Humans; Male; Molecular Sequence Data; Pedigree; Point Mutation; Proteins; Sequence Deletion; Sequence Homology, Amino Acid; Serine; Threonine; Trans-Activators; Valine | 1997 |
Agonist-induced desensitization of the mu opioid receptor is determined by threonine 394 preceded by acidic amino acids in the COOH-terminal tail.
Topics: Alanine; Amino Acid Sequence; Animals; Binding, Competitive; CHO Cells; Cricetinae; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Point Mutation; Rats; Receptors, Opioid, mu; Recombinant Proteins; Serine; Threonine; Transfection | 1997 |
Variable deposition of amyloid beta-protein (A beta) with the carboxy-terminus that ends at residue valine40 (A beta 40) in the cerebral cortex of patients with Alzheimer's disease: a double-labeling immunohistochemical study with antibodies specific for
Topics: Aged; Aged, 80 and over; Alanine; Alzheimer Disease; Amyloid beta-Peptides; Antibodies; Antibody Specificity; Cerebral Cortex; Female; Humans; Immunohistochemistry; Male; Neurofibrillary Tangles; Peptide Fragments; Staining and Labeling; Threonine; Valine | 1997 |
Gain or loss of diabetogenicity resulting from a single point mutation in recombinant encephalomyocarditis virus.
Topics: Alanine; Animals; Antibodies, Viral; Blood Glucose; Cardiovirus Infections; Diabetes Mellitus, Type 1; Encephalomyocarditis virus; Insulin; Mice; Pancreas; Point Mutation; Recombination, Genetic; Threonine | 1997 |
Onset of gluconate-H+ symport in Schizosaccharomyces pombe is regulated by the kinases Wis1 and Pka1, and requires the gti1+ gene product.
Topics: Alanine; Amino Acid Sequence; Biological Transport; Carrier Proteins; Cloning, Molecular; Cyclic AMP-Dependent Protein Kinases; Fungal Proteins; Gene Deletion; Gene Expression; Genes, Fungal; Gluconates; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Protein Serine-Threonine Kinases; Protons; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Threonine | 1997 |
Ala601-Thr type dysplasminogenaemia genetically diagnosed in patients with retinochoroidal vascular disorders.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Base Sequence; Choroid Diseases; Female; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation; Peripheral Vascular Diseases; Plasminogen; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Retinal Diseases; Threonine | 1997 |
Mutations in beta-catenin are uncommon in colorectal cancer occurring in occasional replication error-positive tumors.
Topics: Adult; Aged; Alanine; Amino Acid Substitution; Base Sequence; beta Catenin; Cadherins; Colorectal Neoplasms; Cytoskeletal Proteins; DNA Replication; Exons; Female; Humans; Male; Microsatellite Repeats; Middle Aged; Neoplasm Staging; Phenotype; Point Mutation; Threonine; Trans-Activators; Tumor Cells, Cultured | 1997 |
Xanthine oxidoreductase: dehydrogenase to oxidase conversion.
Topics: Alanine; Amino Acid Substitution; Animals; Cloning, Molecular; Liver; Mutagenesis, Site-Directed; Peptide Fragments; Rats; Recombinant Proteins; Reperfusion Injury; Threonine; Trypsin; Xanthine Dehydrogenase; Xanthine Oxidase | 1997 |
Serine-294 and threonine-295 in the exofacial loop domain between helices 7 and 8 of glucose transporters (GLUT) are involved in the conformational alterations during the transport process.
Topics: Alanine; Amino Acid Sequence; Animals; Biological Transport; COS Cells; Glucose Transporter Type 4; Glycine; Molecular Sequence Data; Monosaccharide Transport Proteins; Muscle Proteins; Mutagenesis, Site-Directed; Protein Conformation; Sequence Homology, Amino Acid; Serine; Threonine | 1998 |
The crucial roles of Asp-314 and Thr-315 in the catalytic activation of molecular oxygen by neuronal nitric-oxide synthase. A site-directed mutagenesis study.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Catalysis; Cattle; Drosophila; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurons; Nitric Oxide Synthase; Oxygen; Rats; Spectrophotometry, Atomic; Structure-Activity Relationship; Threonine | 1998 |
CTLA4 codon 17 dimorphism in patients with rheumatoid arthritis.
Topics: Abatacept; Adult; Aged; Alanine; Antigens, CD; Antigens, Differentiation; Arthritis, Rheumatoid; Codon; CTLA-4 Antigen; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Immunoconjugates; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Threonine | 1998 |
Cysteine 195 has a critical functional role in catalysis by isocitrate lyase from Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cysteine; Escherichia coli; Glycine; Isocitrate Lyase; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Sequence Alignment; Sequence Analysis; Sequence Homology, Amino Acid; Serine; Threonine; Valine | 1997 |
A method for the identification of promoters recognized by RNA polymerase containing a particular sigma factor: cloning of a developmentally regulated promoter and corresponding gene directed by the Streptomyces aureofaciens sigma factor RpoZ.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA-Binding Proteins; DNA-Directed RNA Polymerases; Isoelectric Point; Molecular Sequence Data; Open Reading Frames; Promoter Regions, Genetic; Serine; Sigma Factor; Spores, Bacterial; Streptomyces aureofaciens; Threonine; Transcription, Genetic | 1998 |
Identification of N-terminal residues on P-selectin glycoprotein ligand-1 required for binding to P-selectin.
Topics: Alanine; Amino Acid Sequence; Animals; CHO Cells; Cricetinae; DNA, Complementary; Humans; Membrane Glycoproteins; Molecular Sequence Data; Mutagenesis; P-Selectin; Protein Binding; Recombinant Proteins; Threonine; Tyrosine | 1998 |
Alteration of the fatty acid substrate specificity of lysophosphatidate acyltransferase by site-directed mutagenesis.
Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Acyltransferases; Adenine; Alanine; Amino Acid Substitution; Bacterial Proteins; Binding, Competitive; Dyneins; Escherichia coli; Escherichia coli Proteins; Fatty Acids; Fungal Proteins; Guanine; Leucine; Mutagenesis, Site-Directed; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Temperature; Threonine; Transformation, Bacterial | 1998 |
Biochemical characterization of the 20S proteasome from the methanoarchaeon Methanosarcina thermophila.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Amino Acid Substitution; Archaeal Proteins; Arginine; Asparagine; Aspartic Acid; Base Sequence; Cloning, Molecular; Cysteine Endopeptidases; DNA, Archaeal; Escherichia coli; Glutamine; Ions; Lysine; Methanosarcina; Microscopy, Electron; Molecular Sequence Data; Multienzyme Complexes; Peptides; Phenylalanine; Plasmids; Polymerase Chain Reaction; Sequence Analysis, DNA; Sodium Dodecyl Sulfate; Threonine; Tyrosine | 1998 |
Phosphorylation of the kinase homology domain is essential for activation of the A-type natriuretic peptide receptor.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Atrial Natriuretic Factor; Binding Sites; Cell Line; Enzyme Activation; Glutamic Acid; Guanylate Cyclase; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Octoxynol; Peptide Mapping; Phosphopeptides; Phosphorylation; Receptors, Atrial Natriuretic Factor; Sequence Homology, Amino Acid; Serine; Threonine; Transfection | 1998 |
A phosphorylation site in the ftz homeodomain is required for activity.
Topics: Alanine; Animals; Animals, Genetically Modified; Aspartic Acid; Binding Sites; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA; Drosophila; Drosophila Proteins; Fushi Tarazu Transcription Factors; Homeodomain Proteins; Homeostasis; Mutagenesis, Site-Directed; Phosphorylation; Proto-Oncogene Proteins; Structure-Activity Relationship; Threonine; Transcription Factors; Transcription, Genetic; Wnt1 Protein | 1998 |
Defective intracellular transport of tissue-nonspecific alkaline phosphatase with an Ala162-->Thr mutation associated with lethal hypophosphatasia.
Topics: Alanine; Alkaline Phosphatase; Amino Acid Substitution; Animals; Biological Transport; COS Cells; Endoplasmic Reticulum; Fluorescent Antibody Technique; Glycosylphosphatidylinositols; Hexosaminidases; Hypophosphatasia; Intracellular Fluid; Isoenzymes; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Mutation; Threonine | 1998 |
Computer modelling of dynamics of Ser92X deoxymyoglobin mutants.
Topics: Alanine; Animals; Computer Simulation; Crystallography, X-Ray; Humans; Isoleucine; Models, Molecular; Myoglobin; Point Mutation; Protein Conformation; Serine; Threonine; Valine; Whales | 1998 |
Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity.
Topics: Alanine; Animals; Bacterial Toxins; Crystallography, X-Ray; Enterotoxins; Glutamine; Histidine; Humans; Lysine; Mice; Models, Molecular; Mutation; Rabbits; Staphylococcus aureus; Superantigens; Threonine | 1998 |
Two threonine residues in the M2 segment of the alpha 1 beta 1 GABAA receptor are critical for ion channel function.
Topics: Alanine; Amino Acid Sequence; Cell Membrane; Chloride Channels; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, GABA-A; Threonine; Tritium | 1998 |
Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components.
Topics: Alanine; Amino Acid Substitution; Animals; Annexin A5; Crystallography, X-Ray; DNA Mutational Analysis; Liposomes; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Partial Thromboplastin Time; Phosphatidylcholines; Phosphatidylserines; Rats; Serine; Threonine | 1998 |
Identification and characterization of the major phosphorylation sites of the B-type natriuretic peptide receptor.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Glycine; Guanylate Cyclase; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphorylation; Receptors, Atrial Natriuretic Factor; Serine; Structure-Activity Relationship; Threonine | 1998 |
Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Animals; Biological Transport; CHO Cells; Cricetinae; Enzyme Activation; Glucose; Glucose Transporter Type 4; Insulin; Mice; Molecular Sequence Data; Monosaccharide Transport Proteins; Muscle Proteins; Mutagenesis, Site-Directed; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Ribosomal Protein S6 Kinases; Serine; Threonine | 1998 |
Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Core Binding Factor Alpha 1 Subunit; COS Cells; Dimerization; DNA-Binding Proteins; Glutamine; Mice; Molecular Sequence Data; Neoplasm Proteins; Nuclear Localization Signals; Proline; Proto-Oncogene Proteins c-myc; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Threonine; Transcription Factor AP-2; Transcription Factors; Transcriptional Activation | 1998 |
Point mutations in SP1 motifs in the upstream regulatory region of human papillomavirus type 18 isolates from cervical cancers increase promoter activity.
Topics: Alanine; DNA-Binding Proteins; Erythroid-Specific DNA-Binding Factors; Female; Glycine; HeLa Cells; Humans; Papillomaviridae; Point Mutation; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Sp1 Transcription Factor; Threonine; Transcription Factors; Tumor Cells, Cultured; Uterine Cervical Neoplasms; YY1 Transcription Factor | 1998 |
Homozygous protein C deficiency with a double variant His 202 to Tyr and Ala 346 to Thr.
Topics: Alanine; Amino Acid Substitution; Base Sequence; Consanguinity; Genetic Variation; Histidine; Homozygote; Humans; Infant, Newborn; Male; Mutation; Pedigree; Protein C; Protein C Deficiency; Threonine; Tyrosine | 1998 |
Mitochondrial DNA mutations and pathogenicity.
Topics: Alanine; Cysteine; DNA, Mitochondrial; Female; Fuchs' Endothelial Dystrophy; Glycine; Humans; Mutation; Threonine | 1998 |
Investigation of the role of tyrosine-114 in the activity of human O6-alkylguanine-DNA alkyltranferase.
Topics: Alanine; Amino Acid Sequence; DNA Repair; DNA-Binding Proteins; Enzyme Activation; Glutamic Acid; Guanine; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; O(6)-Methylguanine-DNA Methyltransferase; Oligodeoxyribonucleotides; Phenylalanine; Protein Conformation; Recombinant Proteins; Threonine; Tyrosine | 1998 |
Central diabetes insipidus associated with a missense mutation in the arginine vasopressin gene that replaces Ala at the carboxyterminus of the signal peptide with Thr.
Topics: Adolescent; Alanine; Arginine Vasopressin; Diabetes Insipidus; Exons; Humans; Male; Mutation, Missense; Pituitary Gland, Posterior; Polyuria; Thirst; Threonine | 1998 |
Effect of exceptional valine replacement for highly conserved alanine-55 on the catalytic site structure of chymotrypsin-like serine protease.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cattle; Chymotrypsin; Histidine; Models, Molecular; Molecular Sequence Data; Protein C; Protein Conformation; Sequence Alignment; Serine; Threonine; Valine | 1998 |
Synthetic filaments assembled from C-terminally truncated alpha-synuclein.
Topics: Alanine; alpha-Synuclein; Amino Acid Substitution; Cloning, Molecular; Humans; Microscopy, Electron; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Open Reading Frames; Phosphoproteins; Point Mutation; Proline; Recombinant Proteins; Sequence Deletion; Synucleins; Threonine | 1998 |
Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.
Topics: Age of Onset; Alanine; alpha-Synuclein; Amino Acid Substitution; Circular Dichroism; Humans; Lewy Bodies; Microscopy, Atomic Force; Microscopy, Electron; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Neurons; Parkinson Disease; Phosphoproteins; Point Mutation; Recombinant Proteins; Substantia Nigra; Synucleins; Threonine | 1998 |
Glycerol kinase from Escherichia coli and an Ala65-->Thr mutant: the crystal structures reveal conformational changes with implications for allosteric regulation.
Topics: Alanine; Allosteric Regulation; Amino Acid Substitution; Binding Sites; Crystallography, X-Ray; Dimerization; Escherichia coli; Glycerol Kinase; Protein Conformation; Threonine | 1998 |
Thermodynamics of full agonist, partial agonist, and antagonist binding to wild-type and mutant adenosine A1 receptors.
Topics: Adenosine; Alanine; Amino Acid Substitution; Animals; Binding, Competitive; CHO Cells; Cricetinae; Entropy; Humans; Kinetics; Point Mutation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptors, Purinergic P1; Theophylline; Thermodynamics; Threonine; Transfection; Xanthines | 1998 |
Homozygous mutation (A228T) in the 5alpha-reductase type 2 gene in a boy with 5alpha-reductase deficiency: genotype-phenotype correlations.
Topics: Adolescent; Alanine; Cholestenone 5 alpha-Reductase; Disorders of Sex Development; Female; Genotype; Humans; Male; Mutation; Oxidoreductases; Phenotype; Threonine | 1998 |
Isolation of ATMEKK1 (a MAP kinase kinase kinase)-interacting proteins and analysis of a MAP kinase cascade in Arabidopsis.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Arabidopsis; Calcium-Calmodulin-Dependent Protein Kinases; Cloning, Molecular; DNA, Complementary; Fungal Proteins; Genetic Complementation Test; MAP Kinase Kinase 2; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Threonine | 1998 |
Histidine77, glutamic acid81, glutamic acid123, threonine126, asparagine194, and tryptophan197 of the human emopamil binding protein are required for in vivo sterol delta 8-delta 7 isomerization.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Asparagine; Carrier Proteins; Cell Membrane; Glutamic Acid; Histidine; Humans; Isoenzymes; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Peptide Fragments; Piperidines; Saccharomyces cerevisiae; Steroid Isomerases; Threonine; Tryptophan | 1999 |
Threonine 82 in the regulatory chain is important for nucleotide affinity and for the allosteric stabilization of Escherichia coli aspartate transcarbamoylase.
Topics: Adenosine Triphosphate; Alanine; Allosteric Regulation; Aspartate Carbamoyltransferase; Cytidine Triphosphate; Escherichia coli; Gene Expression Regulation; Kinetics; Mutagenesis, Site-Directed; Regulatory Sequences, Nucleic Acid; Threonine; Uridine Triphosphate | 1998 |
Contribution to Tl+, K+, and Na+ binding of Asn776, Ser775, Thr774, Thr772, and Tyr771 in cytoplasmic part of fifth transmembrane segment in alpha-subunit of renal Na,K-ATPase.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Binding Sites; Cytoplasm; Hydroxides; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Potassium; Protein Structure, Tertiary; Recombinant Proteins; Serine; Sodium; Sodium-Potassium-Exchanging ATPase; Swine; Thallium; Threonine; Tyrosine | 1998 |
Monitoring the sizes of denatured ensembles of staphylococcal nuclease proteins: implications regarding m values, intermediates, and thermodynamics.
Topics: Alanine; Amino Acid Substitution; Chromatography, Gel; Chromatography, High Pressure Liquid; Chymotrypsinogen; Micrococcal Nuclease; Mutagenesis, Site-Directed; Protein Denaturation; Reproducibility of Results; Spectrometry, Fluorescence; Thermodynamics; Threonine; Tryptophan; Urea; Valine | 1998 |
Replacement of threonine 394 by alanine facilitates internalization and resensitization of the rat mu opioid receptor.
Topics: Alanine; Amino Acid Substitution; Analgesics, Opioid; Animals; Cyclic AMP; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gene Expression Regulation, Neoplastic; Mutation; Rats; Receptors, Cell Surface; Receptors, Opioid, mu; Threonine; Tumor Cells, Cultured | 1999 |
Band 3 Tokyo: Thr837-->Ala837 substitution in erythrocyte band 3 protein associated with spherocytic hemolysis.
Topics: Adult; Alanine; Amino Acid Substitution; Anion Exchange Protein 1, Erythrocyte; Humans; Male; Point Mutation; Spherocytosis, Hereditary; Threonine | 1998 |
CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding.
Topics: Alanine; Amino Acid Sequence; Animals; CHO Cells; Chromones; COS Cells; Cricetinae; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Signal Transduction; Threonine | 1999 |
Double mutation (A171T and D444H) is a common cause of profound biotinidase deficiency in children ascertained by newborn screening the the United States. Mutations in brief no. 128. Online.
Topics: Acyltransferases; Alanine; Aspartic Acid; Histidine; Humans; Infant, Newborn; Mutation; Neonatal Screening; Threonine | 1998 |
Impairment of the proapoptotic activity of Bax by missense mutations found in gastrointestinal cancers.
Topics: Alanine; Amino Acid Substitution; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Biological Transport; Cell Line, Transformed; Codon; Dimerization; DNA Mutational Analysis; Ecdysterone; Frameshift Mutation; Gastrointestinal Neoplasms; Humans; Kidney; Methionine; Microsatellite Repeats; Mutation, Missense; Neoplasm Proteins; Protein Binding; Protein Multimerization; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Retinoic Acid; Receptors, Steroid; Recombinant Fusion Proteins; Retinoid X Receptors; Threonine; Transcription Factors; Transfection | 1999 |
A threonine residue in the M2 region of the beta1 subunit is needed for expression of functional alpha1beta1 GABA(A) receptors.
Topics: Action Potentials; Alanine; Animals; Cell Membrane; Gene Expression Regulation; Humans; In Vitro Techniques; Muscimol; Mutation; Protein Binding; Receptors, GABA-A; Receptors, GABA-B; Spodoptera; Threonine | 1999 |
Catalytic roles of divalent metal ions in phosphoryl transfer by EcoRV endonuclease.
Topics: Alanine; Binding Sites; Catalysis; Cations, Divalent; Deoxyribonucleases, Type II Site-Specific; Energy Transfer; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Metals; Mutagenesis, Site-Directed; Phosphates; Protein Conformation; Structure-Activity Relationship; Thermodynamics; Threonine | 1999 |
Misacylation of tRNALys with noncognate amino acids by lysyl-tRNA synthetase.
Topics: Acylation; Adenosine Triphosphate; Alanine; Amino Acids; Cysteine; Escherichia coli; Homocysteine; Hydrolysis; Lactams; Leucine; Lysine-tRNA Ligase; Methionine; Ornithine; RNA Editing; RNA, Transfer, Lys; Threonine | 1999 |
Chromophore-protein-water interactions in the L intermediate of bacteriorhodopsin: FTIR study of the photoreaction of L at 80 K.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Bacteriorhodopsins; Cold Temperature; Halobacterium salinarum; Hydrogen; Models, Molecular; Oxygen; Photochemistry; Schiff Bases; Spectroscopy, Fourier Transform Infrared; Threonine; Tryptophan; Valine; Water | 1999 |
Identification of a novel HLA-DQA1 allele (DQA1*0106) by sequence-based DQA1 typing.
Topics: Alanine; Alleles; Amino Acid Substitution; Base Sequence; Exons; HLA-DQ alpha-Chains; HLA-DQ Antigens; Humans; Molecular Sequence Data; Polymorphism, Genetic; Sequence Alignment; Sequence Analysis, DNA; Threonine | 1999 |
Phosphorylation and/or presence of serine 37 in the movement protein of tomato mosaic tobamovirus is essential for intracellular localization and stability in vivo.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Binding Sites; Fluorescence; Glutamic Acid; Green Fluorescent Proteins; Intracellular Fluid; Luminescent Proteins; Molecular Sequence Data; Mutagenesis; Nicotiana; Phosphoamino Acids; Phosphorylation; Plant Viral Movement Proteins; Plants, Toxic; Protoplasts; Recombinant Fusion Proteins; Serine; Solanum lycopersicum; Threonine; Tobamovirus; Viral Proteins | 1999 |
A novel mutation (A246T) in exon 6 of the proteolipid protein gene associated with connatal Pelizaeus-Merzbacher disease.
Topics: Alanine; Diffuse Cerebral Sclerosis of Schilder; Humans; Male; Myelin Proteolipid Protein; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Threonine | 1999 |
Hydrogen bonding modulates binding of exogenous ligands in a myoglobin proximal cavity mutant.
Topics: Alanine; Amino Acid Substitution; Animals; Binding Sites; Glycine; Histidine; Hydrogen Bonding; Imidazoles; Ligands; Macromolecular Substances; Metmyoglobin; Models, Chemical; Mutagenesis, Insertional; Myoglobin; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; Protons; Serine; Threonine; Whales | 1999 |
A novel missense mutation Thr316Ala in lysosomal acid lipase gene in Japanese population.
Topics: Alanine; Base Sequence; Humans; Japan; Lipase; Lysosomes; Mutation, Missense; Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Threonine | 1999 |
Substitutions in a flexible loop of horse liver alcohol dehydrogenase hinder the conformational change and unmask hydrogen transfer.
Topics: Alanine; Alcohol Dehydrogenase; Amino Acid Substitution; Animals; Crystallography, X-Ray; Electron Transport; Enzyme Activation; Glycine; Horses; Hydrogen; Kinetics; Liver; Mutagenesis, Site-Directed; Proline; Protein Conformation; Substrate Specificity; Threonine | 1999 |
The Ala25-Thr mutation in the thrombomodulin gene is not frequent in Swedish patients suffering from ischemic heart disease.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Female; Gene Frequency; Humans; Male; Middle Aged; Myocardial Ischemia; Point Mutation; Sweden; Threonine; Thrombomodulin | 1999 |
A mutation that causes ataxia shifts the voltage-dependence of the Scn8a sodium channel.
Topics: Alanine; Amino Acid Substitution; Animals; Ataxia; Electrophysiology; Kinetics; Mice; Mutation; NAV1.6 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Oocytes; Reverse Transcriptase Polymerase Chain Reaction; Sodium Channels; Threonine; Xenopus | 1999 |
Domain interactions affecting human DNA topoisomerase I catalysis and camptothecin sensitivity.
Topics: Alanine; Amino Acid Substitution; Camptothecin; Catalysis; DNA; DNA Topoisomerases, Type I; Drug Resistance; Enzyme Inhibitors; Enzyme Stability; Glycine; Humans; Models, Molecular; Mutation; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Threonine; Topoisomerase I Inhibitors; Transfection | 1999 |
Identification and characterization of the phosphorylation sites of the guanylyl cyclase-linked natriuretic peptide receptors A and B.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Cell Line; Glutamic Acid; Guanylate Cyclase; Humans; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphoproteins; Phosphorylation; Receptors, Atrial Natriuretic Factor; Recombinant Proteins; Serine; Threonine | 1999 |
The C-terminal region of human glutathione transferase A1-1 affects the rate of glutathione binding and the ionization of the active-site Tyr9.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Enzyme Stability; Glutathione; Glutathione Transferase; Humans; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Mutagenesis, Site-Directed; Peptide Fragments; Protein Structure, Secondary; Spectrophotometry, Ultraviolet; Threonine; Tyrosine | 1999 |
New ice-binding face for type I antifreeze protein.
Topics: Alanine; Animals; Antifreeze Proteins; Circular Dichroism; Crystallography; Dose-Response Relationship, Drug; Flounder; Glycoproteins; Hydrogen Bonding; Ice; Leucine; Mutagenesis; Protein Binding; Protein Isoforms; Recombinant Proteins; Temperature; Threonine; Ultracentrifugation | 1999 |
Effects of glyphosate and dalapon on total free amino acid profiles of Pseudosuccinea columella snails.
Topics: Alanine; Amino Acids; Animals; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Glyphosate; Herbicides; Propionates; Serine; Snails; Threonine | 2000 |
Presence of 2-furoylmethyl derivatives in hydrolysates of processed tomato products.
Topics: Alanine; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Freeze Drying; Furans; gamma-Aminobutyric Acid; Glutamic Acid; Hydrolysis; Lysine; Maillard Reaction; Serine; Solanum lycopersicum; Threonine | 2000 |
Identification of threonine residues controlling the agonist-dependent phosphorylation and desensitization of the rat A(3) adenosine receptor.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; CHO Cells; Cricetinae; Cysteine; Glutamic Acid; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Threonine | 2000 |
Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid.
Topics: Alanine; alpha-Synuclein; Amino Acid Sequence; Amyloid; Benzothiazoles; Binding Sites; Brain; Circular Dichroism; Congo Red; Endopeptidases; Humans; Hydrolysis; Immunohistochemistry; Lewy Bodies; Microscopy, Atomic Force; Microscopy, Polarization; Molecular Sequence Data; Mutation, Missense; Nerve Tissue Proteins; Parkinson Disease; Postmortem Changes; Proline; Protein Structure, Secondary; Recombinant Proteins; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Synucleins; Thiazoles; Threonine | 2000 |
Sample optimization and identification of signal patterns of amino acid side chains in 2D RFDR spectra of the alpha-spectrin SH3 domain.
Topics: Alanine; Amino Acids; Carbon Isotopes; Chemical Precipitation; Isoleucine; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Proline; Protein Conformation; Serine; Spectrin; src Homology Domains; Threonine; Valine | 2000 |
Identification of a novel missense mutation (T16A) in the glucose-6-phosphatase gene in a Taiwan Chinese patient with glycogen storage disease Ia (Von Gierke disease).
Topics: Alanine; Amino Acid Substitution; Asian People; China; Glucose-6-Phosphatase; Glycogen Storage Disease Type I; Humans; Mutation, Missense; Phenotype; Threonine | 2000 |
Inhibitory effect of novel oral hypoglycemic agent nateglinide (AY4166) on peptide transporters PEPT1 and PEPT2.
Topics: Administration, Oral; Alanine; Animals; Caco-2 Cells; Carrier Proteins; Cyclohexanes; Dipeptides; Humans; Hypoglycemic Agents; Kinetics; Nateglinide; Peptide Transporter 1; Phenylalanine; Rats; Symporters; Threonine | 2000 |
Alpha-synuclein and the Parkinson's disease-related mutant Ala53Thr-alpha-synuclein do not undergo proteasomal degradation in HEK293 and neuronal cells.
Topics: Alanine; alpha-Synuclein; Amino Acid Substitution; Animals; Cell Line; Cysteine Endopeptidases; Humans; Mice; Multienzyme Complexes; Mutation; Nerve Tissue Proteins; Neurons; Parkinson Disease; Proteasome Endopeptidase Complex; Synucleins; Threonine; Transfection | 2000 |
Molecular cloning of a ferret angiotensin II AT(1) receptor reveals the importance of position 163 for Losartan binding.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Alanine; Amino Acid Sequence; Amino Acid Substitution; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Base Sequence; Binding Sites; Binding, Competitive; Cloning, Molecular; COS Cells; DNA, Complementary; DNA, Recombinant; Ferrets; Imidazoles; Iodine Radioisotopes; Losartan; Molecular Sequence Data; Plasmids; Protein Binding; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Threonine | 2000 |
Characterization of a family with dominant hypophosphatasia.
Topics: Alanine; Alkaline Phosphatase; Amino Acid Substitution; Child; Dental Cementum; Dental Enamel Hypoplasia; Diseases in Twins; Ethanolamines; Family Health; Female; Genes, Dominant; Genetic Linkage; Humans; Hypophosphatasia; Male; Pedigree; Point Mutation; Threonine; Tooth Exfoliation; Twins, Dizygotic | 2000 |
Prolonged stationary-phase incubation selects for lrp mutations in Escherichia coli K-12.
Topics: Alanine; Alleles; Bacterial Proteins; Carbon; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Leucine; Leucine-Responsive Regulatory Protein; Mutation; Phenotype; Selection, Genetic; Serine; Threonine; Time Factors; Transcription Factors | 2000 |
Association of CTLA-4 gene A/G polymorphism in Japanese type 1 diabetic patients with younger age of onset and autoimmune thyroid disease.
Topics: Abatacept; Adolescent; Adult; Age of Onset; Aged; Alanine; Antigens, CD; Antigens, Differentiation; Asian People; Autoantibodies; Child; CTLA-4 Antigen; Diabetes Mellitus, Type 1; Female; Glutamate Decarboxylase; Humans; Immunoconjugates; Islets of Langerhans; Isoenzymes; Japan; Male; Middle Aged; Polymorphism, Genetic; Threonine; Thyroiditis, Autoimmune | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Decreased lateral aggregation of a variant recombinant fibrinogen provides insight into the polymerization mechanism.
Topics: Alanine; Ancrod; Blood Coagulation; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinogens, Abnormal; Genetic Variation; Polymers; Recombinant Proteins; Threonine; Thrombin | 2000 |
Monoclonal antibodies identify residues 199-216 of the integrin alpha2 vWFA domain as a functionally important region within alpha2beta1.
Topics: Alanine; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Binding Sites; Cations; Collagen; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epitope Mapping; Epitopes; Glutathione Transferase; Humans; Integrins; Ligands; Magnesium; Manganese; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; Receptors, Collagen; Recombinant Fusion Proteins; Threonine; von Willebrand Factor | 2000 |
Serine 121 is an essential amino acid for biotin sulfoxide reductase functionality.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Binding Sites; Biotin; Catalysis; Chromatography, High Pressure Liquid; Coenzymes; Conserved Sequence; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Factor Xa; Glutathione Transferase; Guanine Nucleotides; Iron-Sulfur Proteins; Ligands; Mass Spectrometry; Metalloproteins; Molecular Sequence Data; Molybdenum Cofactors; Mutagenesis, Site-Directed; NADP; Oxidative Stress; Oxidoreductases; Oxygen; Paraquat; Pteridines; Pterins; Recombinant Fusion Proteins; Rhodobacter sphaeroides; Sequence Homology, Amino Acid; Serine; Spectrometry, Fluorescence; Threonine; Time Factors | 2000 |
Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse alpha-synuclein.
Topics: Alanine; alpha-Synuclein; Amyloid; Animals; Chromatography, Gel; Humans; Mice; Microscopy, Atomic Force; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Parkinson Disease; Protein Conformation; Protein Folding; Protein Precursors; Spectroscopy, Fourier Transform Infrared; Synucleins; Threonine | 2000 |
Directed molecular evolution of cytochrome c peroxidase.
Topics: Alanine; Asparagine; Aspartic Acid; Cloning, Molecular; Cytochrome-c Peroxidase; Directed Molecular Evolution; Enzyme Activation; Gene Library; Genetic Vectors; Guaiacol; Point Mutation; Saccharomyces cerevisiae; Substrate Specificity; Threonine; Tyrosine | 2000 |
Amino acid selectivity in the aminoacylation of coenzyme A and RNA minihelices by aminoacyl-tRNA synthetases.
Topics: Alanine; Amino Acids; Amino Acyl-tRNA Synthetases; Chromatography, Thin Layer; Coenzyme A; Electrophoresis; Escherichia coli; Evolution, Molecular; Isoleucine-tRNA Ligase; Kinetics; Leucine; Lysine-tRNA Ligase; RNA; Serine; Threonine; Time Factors; Valine; Valine-tRNA Ligase | 2000 |
New molecular determinant for inactivation of the human L-type alpha1C Ca2+ channel.
Topics: Alanine; Amino Acid Substitution; Calcium Channels, L-Type; Cell Line; Cloning, Molecular; Fibroblasts; Humans; Kidney; Membrane Potentials; Point Mutation; Recombinant Proteins; Threonine; Transfection | 2000 |
Association between mutations of the follicle-stimulating-hormone receptor and repeated twinning.
Topics: Adenine; Adult; Alanine; Asparagine; Codon; Exons; Female; Genetic Linkage; Guanine; Humans; Phenotype; Point Mutation; Receptors, FSH; Serine; Threonine; Twins, Dizygotic | 2000 |
Identification of a novel T398A mutation in the ND5 subunit of the mitochondrial complex I and of three novel mtDNA polymorphisms in two patients presenting ocular symptoms.
Topics: Alanine; Amino Acid Substitution; DNA, Mitochondrial; Electron Transport Complex I; Female; Humans; Mutation; NADH, NADPH Oxidoreductases; Optic Atrophies, Hereditary; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Threonine | 2000 |
Effects of an Ala54Thr polymorphism in the intestinal fatty acid-binding protein on responses to dietary fat in humans.
Topics: Adipose Tissue; Adult; Alanine; Carrier Proteins; Dietary Fats; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Female; Humans; Intestinal Mucosa; Male; Membrane Lipids; Muscle, Skeletal; Neoplasm Proteins; Obesity; Phospholipids; Polymorphism, Genetic; Threonine; Tumor Suppressor Proteins | 2000 |
A post-translational modification in the GGQ motif of RF2 from Escherichia coli stimulates termination of translation.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Escherichia coli; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Peptide Chain Termination, Translational; Peptide Fragments; Peptide Termination Factors; Protein Processing, Post-Translational; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2000 |
Postprandial responses of individual fatty acids in subjects homozygous for the threonine- or alanine-encoding allele in codon 54 of the intestinal fatty acid binding protein 2 gene.
Topics: Aged; Alanine; Alleles; Carrier Proteins; Cholesterol, VLDL; Chylomicrons; Codon; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Female; Homozygote; Humans; Insulin; Intestines; Lipids; Male; Middle Aged; Neoplasm Proteins; Polymorphism, Genetic; Postprandial Period; Threonine; Time Factors; Tumor Suppressor Proteins | 2001 |
Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69.
Topics: Alanine; Alleles; Bacteriophages; Base Sequence; Cell Division; Chromatography, Gel; Cloning, Molecular; DNA Replication; DNA-Directed DNA Polymerase; Escherichia coli; Genetic Complementation Test; Kinetics; Molecular Sequence Data; Mutagenesis; Mutation; Plasmids; Sequence Homology, Nucleic Acid; Serine; Threonine; Thymidine; Time Factors; Viral Proteins | 2001 |
Novel mutations in the GALK1 gene in patients with galactokinase deficiency.
Topics: Adolescent; Adult; Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Child, Preschool; Cysteine; Female; Galactokinase; Galactosemias; Humans; Male; Methionine; Mice; Molecular Sequence Data; Mutation; Proline; Sequence Deletion; Threonine | 2001 |
In vitro 1H and 31P NMR spectroscopic evidence of multiple aberrant biochemical pathways in murine trisomy 16 brain development.
Topics: Alanine; Animals; Aspartic Acid; Biomarkers; Brain Chemistry; Choline; Creatine; Disease Models, Animal; Down Syndrome; Female; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phosphorus Isotopes; Protons; Taurine; Threonine | 2000 |
Differential effects of the allosteric enhancer (2-amino-4,5-dimethyl-trienyl)[3-trifluoromethyl) phenyl]methanone (PD81,723) on agonist and antagonist binding and function at the human wild-type and a mutant (T277A) adenosine A1 receptor.
Topics: Alanine; Allosteric Regulation; Binding, Competitive; Cells, Cultured; Cyclic AMP; Humans; Mutation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Thiophenes; Threonine | 2001 |
Cosegregation of T108A Elk-1 with mental retardation.
Topics: Alanine; Amino Acid Substitution; DNA-Binding Proteins; ets-Domain Protein Elk-1; Female; Genetic Linkage; Humans; Intellectual Disability; Male; Pedigree; Proto-Oncogene Proteins; Threonine; Transcription Factors; X Chromosome | 2000 |
Expression of HCM causing mutations: lessons learnt from genotype-phenotype studies of the South African founder MYH7 A797T mutation.
Topics: Adolescent; Adult; Aged; Alanine; Amino Acid Substitution; Cardiomyopathy, Hypertrophic; Child; Death, Sudden, Cardiac; Female; Founder Effect; Gene Expression Regulation; Genotype; Humans; Male; Middle Aged; Mutation; Myosin Heavy Chains; Pedigree; Phenotype; Prognosis; Prospective Studies; South Africa; Threonine | 2000 |
Follicle-stimulating-hormone receptor and twinning.
Topics: Alanine; Female; Humans; Mutation; Phenotype; Polymorphism, Genetic; Pregnancy; Pregnancy, Multiple; Receptors, FSH; Threonine; Twins, Dizygotic | 2001 |
Three-dimensional structure of human follicle-stimulating hormone.
Topics: Alanine; Amino Acid Sequence; Chorionic Gonadotropin; Crystallization; Crystallography, X-Ray; Cystine; Follicle Stimulating Hormone; Glycosylation; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Threonine | 2001 |
Role of Thr(11) in the binding of omega-conotoxin MVIIC to N-type Ca2+ channels.
Topics: Alanine; Amino Acid Sequence; Animals; Barium; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cells, Cultured; Cricetinae; Molecular Sequence Data; omega-Conotoxins; Patch-Clamp Techniques; Protein Binding; Rats; Threonine | 2001 |
Hydrophobic analogues of the winter flounder 'antifreeze' protein.
Topics: Alanine; Amino Acid Substitution; Aminobutyrates; Animals; Antifreeze Proteins; Asparagine; Aspartic Acid; Flounder; Freezing; Ice; Isoleucine; Leucine; Protein Engineering; Protein Structure, Secondary; Structure-Activity Relationship; Threonine | 2001 |
Phosphorylation of Ser363, Thr370, and Ser375 residues within the carboxyl tail differentially regulates mu-opioid receptor internalization.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Diprenorphine; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphates; Phosphorylation; Phosphoserine; Phosphothreonine; Rats; Receptors, Opioid, mu; Recombinant Proteins; Serine; Threonine; Transfection | 2001 |
A potential phosphorylation site for an A-type kinase in the Efg1 regulator protein contributes to hyphal morphogenesis of Candida albicans.
Topics: Alanine; Binding Sites; Candida albicans; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Fungal Proteins; Genetic Variation; Morphogenesis; Phosphorylation; Threonine; Transcription Factors | 2001 |
Investigation of allosteric linkages in the regulation of tryptophan synthase: the roles of salt bridges and monovalent cations probed by site-directed mutation, optical spectroscopy, and kinetics.
Topics: Alanine; Allosteric Regulation; Asparagine; Aspartic Acid; Cations, Monovalent; Deuterium; Dimerization; Enzyme Activation; Kinetics; Lysine; Multienzyme Complexes; Mutagenesis, Site-Directed; Potassium; Quaternary Ammonium Compounds; Salmonella typhimurium; Salts; Sodium; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Threonine; Titrimetry; Tryptophan Synthase | 2001 |
Identification of receptor binding and activation determinants in the N-terminal and N-loop regions of the CC chemokine eotaxin.
Topics: Alanine; Asparagine; Binding, Competitive; Calcium; Chemokine CCL11; Chemokines, CC; Cytokines; Dose-Response Relationship, Drug; Humans; Kinetics; Leucine; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Threonine; Time Factors; Transfection; Tumor Cells, Cultured | 2001 |
Phosphorylation mutants elucidate the mechanism of annexin IV-mediated membrane aggregation.
Topics: Alanine; Animals; Annexin A4; Binding Sites; Cattle; Cryoelectron Microscopy; Crystallization; Crystallography, X-Ray; Liposomes; Mutagenesis, Site-Directed; Phosphatidylcholines; Phosphatidylserines; Phosphorylation; Protein Kinase C; Rats; Recombinant Proteins; Threonine | 2001 |
A conserved threonine within Escherichia coli leucyl-tRNA synthetase prevents hydrolytic editing of leucyl-tRNALeu.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Conserved Sequence; DNA Mutational Analysis; Escherichia coli; Hydrolysis; Leucine-tRNA Ligase; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Tertiary; RNA Editing; RNA, Transfer, Leu; Threonine; Transfer RNA Aminoacylation | 2001 |
Role of enzyme-ribofuranosyl contacts in the ground state and transition state for orotidine 5'-phosphate decarboxylase: a role for substrate destabilization?
Topics: Alanine; Aspartic Acid; Catalysis; Enzyme Stability; Kinetics; Orotidine-5'-Phosphate Decarboxylase; Ribosemonophosphates; Saccharomyces cerevisiae; Substrate Specificity; Threonine; Uridine Monophosphate | 2001 |
Mutations in the G-domain of elongation factor G from Thermus thermophilus affect both its interaction with GTP and fusidic acid.
Topics: Alanine; Aspartic Acid; Binding Sites; Cell-Free System; Fusidic Acid; Genetic Variation; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Peptide Elongation Factor G; Poly U; Protein Biosynthesis; Protein Structure, Tertiary; Recombinant Proteins; Thermus thermophilus; Threonine | 2001 |
Engineering a functional blue-wavelength-shifted rhodopsin mutant.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Cattle; COS Cells; Glutamic Acid; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Photochemistry; Retinaldehyde; Rhodopsin; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thermodynamics; Threonine; Transducin | 2001 |
Role of phylogenetically conserved amino acids in folding of Na,K-ATPase.
Topics: Alanine; Amino Acid Substitution; Amino Acids; Animals; Asparagine; Cell Membrane; Conserved Sequence; Endoplasmic Reticulum; Enzyme Activation; Gene Expression Regulation, Fungal; Lysine; Mutagenesis, Site-Directed; Peptide Fragments; Phylogeny; Protein Folding; Recombinant Proteins; RNA, Messenger; Saccharomyces cerevisiae; Serine; Sodium-Potassium-Exchanging ATPase; Swine; Temperature; Threonine | 2001 |
Nuclear extracellular signal-regulated kinase 2 phosphorylates p53 at Thr55 in response to doxorubicin.
Topics: Alanine; Amino Acid Substitution; Cell Line; Cell Nucleus; Cloning, Molecular; Doxorubicin; Female; Humans; Mitogen-Activated Protein Kinase 1; Mutagenesis, Site-Directed; Phosphoproteins; Phosphorylation; Phosphothreonine; Protein Binding; Recombinant Proteins; Threonine; Tumor Suppressor Protein p53; Uterine Cervical Neoplasms | 2001 |
Association of the Ala54-Thr polymorphism in the intestinal fatty acid-binding protein with 2-h postchallenge insulin levels in the Framingham Offspring Study.
Topics: Alanine; Alcohol Drinking; Apolipoproteins E; Blood Glucose; Cardiovascular Diseases; Carrier Proteins; Cholesterol; Cohort Studies; Diabetes Mellitus, Type 2; DNA; Estrogen Replacement Therapy; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Female; Genetic Carrier Screening; Genotype; Glycated Hemoglobin; Homozygote; Humans; Insulin; Insulin Secretion; Male; Massachusetts; Middle Aged; Neoplasm Proteins; Polymorphism, Genetic; Postmenopause; Prospective Studies; Risk Factors; Sex Characteristics; Smoking; Threonine; Triglycerides; Tumor Suppressor Proteins | 2001 |
Kinetic mechanism and regulation of myosin VI.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Amino Acid Substitution; Animals; Glutamic Acid; Kinetics; Myosin Heavy Chains; Protein Binding; Pyrenes; Spectrometry, Fluorescence; Swine; Threonine | 2001 |
Substitution of Thr for Ala-237 in TEM-17, TEM-12 and TEM-26: alterations in beta-lactam resistance conferred on Escherichia coli.
Topics: Alanine; Amino Acid Substitution; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Escherichia coli; Isoelectric Point; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Threonine | 2001 |
Myosin II dynamics and cortical flow during contractile ring formation in Dictyostelium cells.
Topics: Alanine; Animals; Argon; Detergents; Dictyostelium; Green Fluorescent Proteins; Lasers; Luminescent Proteins; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Myosins; Octoxynol; Phosphorylation; Recombinant Fusion Proteins; Threonine; Time Factors | 2001 |
Recognition of fibronectin by the platelet integrin alpha IIb beta 3 involves an extended interface with multiple electrostatic interactions.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Antibodies, Monoclonal; Arginine; Aspartic Acid; Binding Sites, Antibody; Binding, Competitive; Fibronectins; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligopeptides; Peptide Fragments; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Folding; Static Electricity; Threonine | 2001 |
Pre-steady-state kinetic studies of Saccharomyces cerevisiae myristoylCoA:protein N-myristoyltransferase mutants identify residues involved in catalysis.
Topics: Acyltransferases; Adenosine Triphosphatases; Alanine; Amino Acid Substitution; Animals; Arsenate Reductases; Arsenite Transporting ATPases; Asparagine; Catalysis; Cattle; Ion Pumps; Kinetics; Leucine; Multienzyme Complexes; Mutagenesis, Site-Directed; Myristic Acid; Peptide Fragments; Phenylalanine; Rabbits; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Deletion; Spectrometry, Fluorescence; Substrate Specificity; Swine; Threonine | 2001 |
The polymorphism at codon 54 of the FABP2 gene increases fat absorption in human intestinal explants.
Topics: Absorption; Alanine; Apolipoprotein A-I; Apolipoproteins B; Carrier Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Heterozygote; Homozygote; Humans; Jejunum; Microvilli; Neoplasm Proteins; Oleic Acid; Organ Culture Techniques; Polymorphism, Single Nucleotide; Threonine; Triglycerides; Tumor Suppressor Proteins | 2001 |
Design and characterization of a highly selective peptide inhibitor of the small conductance calcium-activated K+ channel, SkCa2.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Cell Line; Cloning, Molecular; COS Cells; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; Humans; Kinetics; Methionine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Neurotoxins; PC12 Cells; Peptides; Phenylalanine; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Protein Binding; Rats; Scorpion Venoms; Sequence Homology, Amino Acid; Small-Conductance Calcium-Activated Potassium Channels; Threonine; Transfection; Valine | 2001 |
Crystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate: a mosaic framework containing 83 mutations.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Asparagine; Binding Sites; Carrier Proteins; Crystallography, X-Ray; Drug Resistance; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Penicillin-Binding Proteins; Penicillins; Protein Binding; Protein Conformation; Streptococcus pneumoniae; Threonine | 2001 |
Tissues of the clawed frog Xenopus laevis contain two closely related forms of UDP-GlcNAc:alpha3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Blotting, Northern; Blotting, Southern; DNA Probes; DNA, Complementary; Isoenzymes; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Acetylglucosaminyltransferases; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Threonine; Xenopus laevis | 2001 |
Association of gene polymorphism of polymeric immunoglobulin receptor and IgA nephropathy.
Topics: Alanine; Alleles; Genetic Markers; Genotype; Glomerulonephritis, IGA; Glycine; Humans; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Receptors, Fc; Receptors, Polymeric Immunoglobulin; Sequence Analysis, DNA; Threonine | 2001 |
The impact of codon 54 variation in intestinal fatty acid binding protein gene on the pathogenesis of diabetes mellitus in Chinese.
Topics: Alanine; Asian People; Carrier Proteins; China; Codon; Diabetes Mellitus, Type 2; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Genetic Variation; Humans; Insulin; Insulin Resistance; Insulin Secretion; Neoplasm Proteins; Threonine; Tumor Suppressor Proteins | 1999 |
Identification of the phosphatidylserine binding site in the C2 domain that is important for PKC alpha activation and in vivo cell localization.
Topics: Alanine; Animals; Arginine; Asparagine; Binding Sites; Calcium; Cell Line; Cell Membrane; COS Cells; Enzyme Activation; Humans; Isoenzymes; Liposomes; Lysine; Micelles; Mutagenesis, Site-Directed; Phosphatidylserines; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Protein Structure, Tertiary; Protein Transport; Threonine | 2001 |
Importance of the conserved nucleotides around the tRNA-like structure of Escherichia coli transfer-messenger RNA for protein tagging.
Topics: Acylation; Alanine; Arginine; Bacterial Proteins; Base Sequence; Binding Sites; Blotting, Northern; Conserved Sequence; Escherichia coli; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Open Reading Frames; Peptide Elongation Factor Tu; Ribosomal Proteins; Ribosomes; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Serine; Threonine | 2001 |
Combinatorial interactions of two amino acids with a single base pair define target site specificity in plant dimeric homeodomain proteins.
Topics: Alanine; Amino Acid Sequence; Base Pairing; Base Sequence; Binding Sites; Dimerization; DNA, Plant; Homeodomain Proteins; Models, Biological; Molecular Sequence Data; Mutation; Plant Proteins; Recombinant Fusion Proteins; Threonine | 2001 |
Resolution of enantiomers of DL-amino acids on silica gel plates impregnated with optically pure (-)-quinine.
Topics: Acetates; Acetic Acid; Alanine; Amino Acids; Butanols; Carbon Tetrachloride; Chloroform; Chromatography, Thin Layer; Methionine; Propionates; Quinine; Silica Gel; Silicon Dioxide; Solvents; Stereoisomerism; Threonine; Valine | 2001 |
Mechanisms for intragenic complementation at the human argininosuccinate lyase locus.
Topics: Alanine; Amino Acid Substitution; Arginine; Argininosuccinate Lyase; Aspartic Acid; Binding Sites; Enzyme Activation; Enzyme Stability; Genetic Complementation Test; Genetic Markers; Glutamine; Glycine; Humans; Methionine; Mutagenesis, Site-Directed; Recombinant Proteins; Threonine | 2001 |
Role of nucleotidyl transferase motif V in strand joining by chlorella virus DNA ligase.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; DNA; DNA Ligases; DNA Mutational Analysis; DNA Nucleotidyltransferases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutamine; Kinetics; Lysine; Molecular Sequence Data; Mutation; Mutation, Missense; Point Mutation; Protein Binding; Protein Structure, Tertiary; Threonine; Time Factors; Viral Proteins | 2002 |
The association of Ala45Thr polymorphism in NeuroD with child-onset Type 1a diabetes in Japanese.
Topics: Adolescent; Age of Onset; Alanine; Alleles; Asian People; Basic Helix-Loop-Helix Transcription Factors; Child; Diabetes Mellitus, Type 1; Genetic Carrier Screening; Genetic Predisposition to Disease; Genetic Variation; Helix-Loop-Helix Motifs; HLA-DR Antigens; HLA-DRB1 Chains; Homozygote; Humans; Japan; Nerve Tissue Proteins; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Reference Values; Threonine; Time Factors | 2002 |
[A novel point mutation in the transmembrane domain of platelet glycoprotein IX gene identified in a Bernard-Soulier syndrome patient].
Topics: Adult; Alanine; Bernard-Soulier Syndrome; Cell Size; Female; Humans; Membrane Proteins; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Point Mutation; Protein Structure, Tertiary; Ristocetin; Threonine; Thrombocytopenia | 2001 |
Site-directed mutagenesis of heparin-binding EGF-like growth factor (HB-EGF): analysis of O-glycosylation sites and properties.
Topics: Alanine; Binding Sites; Blotting, Western; Chromatography, High Pressure Liquid; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Genetic Vectors; Glycosylation; HeLa Cells; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Mutation; Polymerase Chain Reaction; Recombinant Proteins; Threonine; Vaccinia virus | 2001 |
An N-terminal arginine-rich cluster and a proline-alanine-threonine repeat region determine the cellular localization of the herpes simplex virus type 1 ICP34.5 protein and its ligand, protein phosphatase 1.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Base Sequence; Cell Compartmentation; Chlorocebus aethiops; DNA Primers; Fluorescent Antibody Technique, Indirect; Ligands; Molecular Sequence Data; Phosphoprotein Phosphatases; Proline; Protein Phosphatase 1; Recombinant Proteins; Repetitive Sequences, Amino Acid; Subcellular Fractions; Threonine; Vero Cells; Viral Proteins | 2002 |
Essential hydrophilic carboxyl-terminal regions including cysteine residues of the yeast stretch-activated calcium-permeable channel Mid1.
Topics: Alanine; Alleles; Asparagine; Binding Sites; Calcium; Calcium Channels; Codon; Codon, Nonsense; Cysteine; Fungal Proteins; Hydroxylamine; Immunoblotting; Membrane Glycoproteins; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine; Time Factors; Tryptophan; Two-Hybrid System Techniques | 2002 |
Hydration effects of heparin on antithrombin probed by osmotic stress.
Topics: Alanine; Antithrombins; Asparagine; Binding Sites; Heparin; Isoleucine; Kinetics; Leucine; Models, Molecular; Osmotic Pressure; Protein Binding; Serine; Spectrometry, Fluorescence; Thermodynamics; Threonine; Time Factors; Tryptophan; Valine; Water; X-Rays | 2002 |
Binding characteristics of cetirizine and levocetirizine to human H(1) histamine receptors: contribution of Lys(191) and Thr(194).
Topics: Alanine; Amino Acid Substitution; Animals; Binding, Competitive; Cetirizine; CHO Cells; Cloning, Molecular; Cricetinae; Humans; Kinetics; Lysine; Mutagenesis; Receptors, Histamine H1; Threonine; Transfection | 2002 |
The simultaneous biosynthesis and uptake of amino acids by Lactococcus lactis studied by (13)C-labeling experiments.
Topics: Alanine; Amino Acids; Aspartic Acid; Biomass; Cell Membrane; Computer Simulation; Culture Media; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Isotope Labeling; Lactococcus lactis; Models, Biological; Models, Chemical; Phenylalanine; Threonine | 2002 |
No association found between the Ala54Thr polymorphism of FABP2 gene and obesity and obesity with dyslipidemia in Japanese schoolchildren.
Topics: Adolescent; Alanine; Base Sequence; Carrier Proteins; Child; DNA Primers; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Female; Humans; Hyperlipidemias; Japan; Male; Neoplasm Proteins; Obesity; Polymorphism, Genetic; Threonine; Tumor Suppressor Proteins | 2001 |
A novel Ala(-3)Thr mutation in the signal peptide of human luteinizing hormone beta-subunit: potentiation of the inositol phosphate signalling pathway and attenuation of the adenylate cyclase pathway by recombinant variant hormone.
Topics: Adenylyl Cyclases; Alanine; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Culture Media; Cyclic AMP; Glycoprotein Hormones, alpha Subunit; Humans; Inositol Phosphates; Luteinizing Hormone; MAP Kinase Signaling System; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymorphism, Genetic; Progesterone; Protein Sorting Signals; Receptors, LH; Recombinant Fusion Proteins; Sequence Analysis, Protein; Threonine; Tumor Cells, Cultured | 2002 |
Association between a novel variant of the human type 2 deiodinase gene Thr92Ala and insulin resistance: evidence of interaction with the Trp64Arg variant of the beta-3-adrenergic receptor.
Topics: Alanine; Blood Glucose; Glucose Clamp Technique; Heterozygote; Homozygote; Humans; Insulin; Insulin Resistance; Iodide Peroxidase; Isoenzymes; Middle Aged; Mutation, Missense; Obesity; Receptors, Adrenergic, beta-3; Threonine | 2002 |
Probing the proton channel and the retinal binding site of Natronobacterium pharaonis sensory rhodopsin II.
Topics: Alanine; Archaeal Proteins; Binding Sites; Carotenoids; Cell Membrane; Cytoplasm; DNA; Escherichia coli; Halorhodopsins; Hydrogen-Ion Concentration; Lasers; Light; Lipid Metabolism; Models, Molecular; Mutation; Natronobacterium; Protein Structure, Tertiary; Protons; Rhodopsins, Microbial; Sensory Rhodopsins; Threonine | 2002 |
Transthyretin Thr60Ala Appalachian-type mutation in a Japanese family with familial amyloidotic polyneuropathy.
Topics: Aged; Alanine; Amino Acid Sequence; Amyloid Neuropathies, Familial; Base Sequence; DNA; Female; Humans; Japan; Male; Point Mutation; Prealbumin; Threonine | 2002 |
Atypical muscle pathology and a survey of cis-mutations in deaf patients harboring a 1555 A-to-G point mutation in the mitochondrial ribosomal RNA gene.
Topics: Adult; Alanine; Anti-Bacterial Agents; Audiology; Cysteine; Cytochrome b Group; Deafness; DNA, Mitochondrial; Female; Glycine; Hearing; Humans; Male; Middle Aged; Muscle, Skeletal; Mutation; Pedigree; Point Mutation; RNA; RNA, Mitochondrial; RNA, Ribosomal; Streptomycin; Threonine | 2002 |
The synergistic anion-binding sites of human transferrin: chemical and physiological effects of site-directed mutagenesis.
Topics: Alanine; Anions; Arginine; Binding Sites; Carbonic Acid; Drug Synergism; Electron Spin Resonance Spectroscopy; Humans; Iron; K562 Cells; Kinetics; Mutagenesis, Site-Directed; Nitrilotriacetic Acid; Peptide Fragments; Recombinant Proteins; Serine; Spectrophotometry; Threonine; Transferrin | 2002 |
Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice.
Topics: Alanine; alpha-Synuclein; Animals; Humans; Mice; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Parkinson Disease; Reverse Transcriptase Polymerase Chain Reaction; Synucleins; Threonine | 2002 |
Identification of two C-terminal amino acids, Ser(355) and Thr(357), required for short-term homologous desensitization of mu-opioid receptors.
Topics: Alanine; Amino Acid Substitution; Cells, Cultured; Humans; Phosphorylation; Protein Structure, Tertiary; Receptors, Opioid, mu; Serine; Threonine | 2002 |
Association of human papillomavirus type 58 variant with the risk of cervical cancer.
Topics: Adult; Alanine; Base Sequence; Cysteine; Female; Genetic Variation; Glycine; Hong Kong; Humans; Middle Aged; Molecular Sequence Data; Neoplasm Invasiveness; Odds Ratio; Papillomaviridae; Papillomavirus Infections; Point Mutation; Prevalence; Risk; Severity of Illness Index; Threonine; Tumor Virus Infections; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms | 2002 |
Variation in the fatty acid binding protein 2 gene is not associated with markers of metabolic syndrome in patients with coronary heart disease.
Topics: Adult; Aged; Alanine; Alleles; Blood Pressure; Body Mass Index; Carrier Proteins; Codon; Coronary Disease; Cross-Sectional Studies; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Female; Finland; Gene Frequency; Genetic Variation; Genotype; Humans; Insulin Resistance; Lipids; Male; Metabolic Syndrome; Middle Aged; Neoplasm Proteins; Polymorphism, Genetic; Threonine; Tumor Suppressor Proteins | 2002 |
Site-directed mutagenesis of conserved charged amino acid residues in ClpB from Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids, Acidic; Amino Acids, Basic; Arginine; Conserved Sequence; Endopeptidase Clp; Escherichia coli Proteins; Glutamic Acid; Heat-Shock Proteins; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Threonine | 2002 |
Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress.
Topics: Adenoviridae; Alanine; Amino Acid Sequence; Animals; Apoptosis; Binding Sites; Blotting, Western; Cell Line; Cell Survival; DNA, Complementary; Escherichia coli; Humans; Hydrogen Peroxide; Mice; Mitochondria; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Oxidative Stress; Oxygen; p38 Mitogen-Activated Protein Kinases; Phosphoric Monoester Hydrolases; Phosphorylation; Plasmids; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-bcl-2; Sequence Homology, Amino Acid; Serine; Threonine; Transfection | 2002 |
Ca2+-stimulated Ca2+ oscillations produced by the Ca2+-sensing receptor require negative feedback by protein kinase C.
Topics: Alanine; Binding Sites; Calcium; Carcinogens; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Mutation; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Binding; Protein Isoforms; Protein Kinase C; Receptors, Calcium-Sensing; Receptors, Cell Surface; Threonine; Time Factors; Transfection | 2002 |
The activity of the Arabidopsis bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase enzyme of lysine catabolism is regulated by functional interaction between its two enzyme domains.
Topics: Alanine; Arabidopsis; Aspartic Acid; Casein Kinase II; Chromatography, Gel; Dimerization; Dose-Response Relationship, Drug; Egtazic Acid; Lysine; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Recombinant Proteins; Saccharopine Dehydrogenases; Serine; Sodium Chloride; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2002 |
Transfection of p27(Kip1) threonine residue 187 mutant type gene, which is not influenced by ubiquitin-mediated degradation, induces cell cycle arrest in oral squamous cell carcinoma cells.
Topics: Alanine; Blotting, Western; Carcinoma, Squamous Cell; Cell Cycle; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Flow Cytometry; Genetic Therapy; Humans; Mouth Neoplasms; Mutation; Threonine; Transfection; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2002 |
A novel androgen receptor mutant, A748T, exhibits hormone concentration-dependent defects in nuclear accumulation and activity despite normal hormone-binding affinity.
Topics: Alanine; Animals; Binding Sites; Biological Transport; Cell Nucleus; COS Cells; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Stability; Gene Expression; Heat-Shock Proteins; Humans; Male; Metribolone; Models, Molecular; Mutation; Prostatic Neoplasms; Protein Conformation; Receptors, Androgen; Structure-Activity Relationship; Testosterone; Threonine; Transcription, Genetic; Transfection | 2002 |
The influence of Ala243 (Gly247), Arg215 and Thr226 (Asn230) on the bioluminescence spectra and pH-sensitivity of railroad worm, click beetle and firefly luciferases.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Asparagine; Coleoptera; Conserved Sequence; Hydrogen-Ion Concentration; Luciferases; Luminescence; Molecular Sequence Data; Sequence Alignment; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Structure-Activity Relationship; Threonine | 2002 |
Crucial role of conserved lysine 277 in the fidelity of tRNA aminoacylation by Escherichia coli valyl-tRNA synthetase.
Topics: Acylation; Adenosine Monophosphate; Alanine; Amino Acid Sequence; Binding Sites; Catalytic Domain; Conserved Sequence; Escherichia coli Proteins; Lysine; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; RNA Editing; RNA, Transfer, Thr; RNA, Transfer, Val; Sequence Alignment; Sequence Homology, Amino Acid; Threonine; Valine-tRNA Ligase | 2002 |
[Association of the renin-angiotensin system gene polymorphism with nephropathy in type II diabetes].
Topics: Adult; Alanine; Alleles; Angiotensinogen; Case-Control Studies; Cysteine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Female; Genotype; Humans; Male; Methionine; Middle Aged; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin-Angiotensin System; Threonine | 2002 |
An expanded V2 receptor retention signal.
Topics: Alanine; Amino Acid Motifs; Cell Line; Cytoplasm; Humans; Ligands; Mutagenesis; Mutagenesis, Site-Directed; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Receptors, Vasopressin; Serine; Signal Transduction; Threonine; Time Factors; Transfection | 2002 |
Identification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibition.
Topics: Alanine; Algorithms; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Blotting, Western; Carnitine Acyltransferases; Carnitine O-Palmitoyltransferase; Catalysis; Cysteine; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Kinetics; Malonyl Coenzyme A; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Point Mutation; Protein Binding; Protein Isoforms; Rats; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Threonine | 2003 |
Understanding the dynamics of Spinocerebellar Ataxia 8 (SCA8) locus through a comparative genetic approach in humans and apes.
Topics: Alanine; Alleles; Animals; Cysteine; Genetic Variation; Glycine; Gorilla gorilla; Humans; Nerve Tissue Proteins; Pan troglodytes; Polymerase Chain Reaction; Pongo pygmaeus; Risk Factors; RNA, Long Noncoding; RNA, Untranslated; Species Specificity; Spinocerebellar Degenerations; Threonine; Trinucleotide Repeat Expansion | 2003 |
Proline oxidase induces apoptosis in tumor cells, and its expression is frequently absent or reduced in renal carcinomas.
Topics: Alanine; Apoptosis; Arginine; Blotting, Western; Carcinoma; DNA, Complementary; Flow Cytometry; Green Fluorescent Proteins; Histidine; Humans; Immunohistochemistry; Kidney; Kidney Neoplasms; Luminescent Proteins; Oligonucleotides, Antisense; Phenylalanine; Plasmids; Proline Oxidase; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Threonine; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Up-Regulation | 2003 |
Genetic variation in cyclooxygenase 1: effects on response to aspirin.
Topics: Adult; Alanine; Aspirin; Blood Platelets; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Cysteine; Dinoprost; DNA, Complementary; Ethanol; Female; Glycine; Humans; Isoenzymes; Male; Membrane Proteins; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymerase Chain Reaction; Polymorphism, Genetic; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Reference Values; Sequence Analysis, DNA; Sex Characteristics; Threonine; Thromboxane B2 | 2003 |
Slow binding of retinal to rhodopsin mutants G90D and T94D.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Glutamic Acid; Glutamine; Glycine; Humans; Molecular Sequence Data; Mutagenesis, Insertional; Night Blindness; Protein Binding; Protein Denaturation; Retinaldehyde; Rhodopsin; Schiff Bases; Spectrophotometry, Ultraviolet; Threonine | 2003 |
Influence of interleukin-12 receptor beta1 polymorphisms on tuberculosis.
Topics: Adult; Aged; Alanine; Asian People; Blotting, Western; Case-Control Studies; Cysteine; Female; Genetic Predisposition to Disease; Genotype; Glycine; Haplotypes; Humans; Interferon-gamma; Japan; Killer Cells, Natural; Male; Middle Aged; Mutation, Missense; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Receptors, Interleukin; Receptors, Interleukin-12; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Threonine; Tuberculosis | 2003 |
Mechanism of flavin mononucleotide cofactor binding to the Desulfovibrio vulgaris flavodoxin. 1. Kinetic evidence for cooperative effects associated with the binding of inorganic phosphate and the 5'-phosphate moiety of the cofactor.
Topics: Alanine; Apoproteins; Asparagine; Binding Sites; Desulfovibrio vulgaris; Flavin Mononucleotide; Flavodoxin; Histidine; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Phosphates; Protein Binding; Riboflavin; Spectrometry, Fluorescence; Thermodynamics; Threonine; Tryptophan; Tyrosine | 2003 |
Genetic variations of gpx-4 and male infertility in humans.
Topics: Alanine; Alleles; Amino Acid Substitution; Case-Control Studies; Genetic Variation; Glutathione Peroxidase; Homozygote; Humans; Infertility, Male; Male; Phospholipid Hydroperoxide Glutathione Peroxidase; Promoter Regions, Genetic; Threonine | 2003 |
NMR determination of pKa values for Asp, Glu, His, and Lys mutants at each variable contiguous enzyme-inhibitor contact position of the turkey ovomucoid third domain.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Binding Sites; Genetic Variation; Glutamic Acid; Glycine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Lysine; Models, Chemical; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Ovomucin; Protein Conformation; Protein Structure, Tertiary; Serine Proteinase Inhibitors; Thermodynamics; Threonine; Titrimetry; Turkeys | 2003 |
NEUROD polymorphism Ala45Thr is associated with Type 1 diabetes mellitus in Czech children.
Topics: Adolescent; Age of Onset; Alanine; Base Sequence; Basic Helix-Loop-Helix Transcription Factors; Child; Czech Republic; Diabetes Mellitus, Type 1; DNA Primers; Gene Frequency; Helix-Loop-Helix Motifs; HLA-DQ Antigens; Humans; Insulin; Mutation, Missense; Nerve Tissue Proteins; Polymerase Chain Reaction; Regression Analysis; Threonine | 2003 |
Homotropic versus heterotopic cooperativity of cytochrome P450eryF: a substrate oxidation and spectral titration study.
Topics: Alanine; Androstenedione; Atrial Natriuretic Factor; Bacteria; Bacterial Proteins; Binding Sites; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Flavones; Flavonoids; In Vitro Techniques; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Oxidation-Reduction; Pyrenes; Quinolines; Structure-Activity Relationship; Substrate Specificity; Threonine; Titrimetry | 2003 |
Mu opioid receptor gene polymorphisms and heroin dependence in Asian populations.
Topics: Alanine; Asia; Case-Control Studies; Chi-Square Distribution; Cysteine; Ethnicity; Exons; Gene Frequency; Genotype; Glycine; Heroin Dependence; Humans; Linkage Disequilibrium; Mutation; Polymorphism, Genetic; Receptors, Opioid, mu; Threonine | 2003 |
Transcriptional activity and DNA binding of heat shock factor-1 involve phosphorylation on threonine 142 by CK2.
Topics: Alanine; Amino Acid Substitution; Animals; Brain; Casein Kinase II; Cattle; DNA-Binding Proteins; Heat Shock Transcription Factors; HeLa Cells; Humans; Mutagenesis, Site-Directed; Phosphorylation; Phosphothreonine; Protein Serine-Threonine Kinases; Recombinant Proteins; Threonine; Transcription Factors; Transcription, Genetic | 2003 |
Mutation Ala(171)Thr stabilizes the gonadotropin-releasing hormone receptor in its inactive conformation, causing familial hypogonadotropic hypogonadism.
Topics: Adult; Alanine; Binding Sites; Cell Line; Embryo, Mammalian; Gene Expression; Humans; Hydrogen Bonding; Hypogonadism; Kidney; Male; Models, Molecular; Mutation; Pedigree; Protein Conformation; Receptors, LHRH; Signal Transduction; Structure-Activity Relationship; Threonine; Type C Phospholipases | 2003 |
Threonine phosphorylation sites in the beta 2 and beta 7 leukocyte integrin polypeptides.
Topics: Alanine; Amino Acid Sequence; Animals; CD18 Antigens; Cell Adhesion; Cell Line; Chlorocebus aethiops; COS Cells; Cytoplasm; Humans; Integrin beta Chains; Integrins; Lymphocyte Activation; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Okadaic Acid; Peptide Mapping; Phorbol 12,13-Dibutyrate; Phosphopeptides; Phosphorylation; Protein Structure, Tertiary; Receptor-CD3 Complex, Antigen, T-Cell; T-Lymphocyte Subsets; Threonine; Transfection; Tumor Cells, Cultured; Vascular Cell Adhesion Molecule-1 | 2003 |
Detection of an Ala601Thr mutation of plasminogen gene in 3 out of 36 Korean patients with deep vein thrombosis.
Topics: Adult; Aged; Alanine; Female; Humans; Korea; Male; Middle Aged; Plasminogen; Point Mutation; Risk Factors; Sequence Analysis, DNA; Threonine; Venous Thrombosis | 2003 |
ABCA1 gene polymorphisms and their associations with coronary artery disease and plasma lipids in males from three ethnic populations in Singapore.
Topics: Alanine; Apolipoprotein A-I; Asian People; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Cysteine; Genotype; Glycine; Haplotypes; Humans; India; Isoleucine; Linkage Disequilibrium; Lipids; Malaysia; Male; Methionine; Polymorphism, Genetic; Sequence Analysis, DNA; Singapore; Threonine; Triglycerides; Valine; White People | 2003 |
Apolipoprotein E, angiotensin-converting enzyme and alpha-1-antichymotrypsin genotypes are not associated with post-stroke dementia.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Alleles; alpha 1-Antitrypsin; Apolipoproteins E; Cysteine; Dementia; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation; Neuropsychological Tests; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Promoter Regions, Genetic; Stroke; Threonine | 2003 |
Phosphorylation of threonine 10 on CKBBP1/SAG/ROC2/Rbx2 by protein kinase CKII promotes the degradation of IkappaBalpha and p27Kip1.
Topics: Alanine; Casein Kinase II; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinase Inhibitor p27; Cysteine Endopeptidases; Enzyme Inhibitors; G1 Phase; Gene Expression; Guanosine Triphosphate; HeLa Cells; Humans; I-kappa B Proteins; Leupeptins; Multienzyme Complexes; Mutagenesis, Site-Directed; NF-KappaB Inhibitor alpha; Phosphorylation; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; RNA; RNA-Binding Proteins; S Phase; Structure-Activity Relationship; Threonine; Transfection; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases | 2003 |
Autophosphorylation of threonine 485 in the activation loop is essential for attaining eIF2alpha kinase activity of HRI.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Blotting, Western; Cell Line; Chromatography, Thin Layer; Dose-Response Relationship, Drug; eIF-2 Kinase; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Eukaryotic Initiation Factor-2; Heme; Hemin; Humans; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Phosphorylation; Protein Structure, Tertiary; Threonine; Trypsin | 2003 |
Blocking survivin to kill cancer cells.
Topics: Alanine; Antineoplastic Agents; Apoptosis; Cell Death; Cell Line, Tumor; DNA, Complementary; Genes, Dominant; Genetic Techniques; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Multigene Family; Mutation; Neoplasm Proteins; Neoplasms; Oligonucleotides, Antisense; Plasmids; Point Mutation; Prognosis; Survivin; Threonine | 2003 |
Polymorphisms in thyroid hormone pathway genes are associated with plasma TSH and iodothyronine levels in healthy subjects.
Topics: Adult; Alanine; Amino Acid Substitution; Female; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Reference Values; Threonine; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine | 2003 |
Exploring the effects of methylenetetrahydrofolate reductase gene variants C677T and A1298C on the risk of orofacial clefts in 261 Norwegian case-parent triads.
Topics: Adolescent; Adult; Alanine; Case-Control Studies; Cleft Lip; Cleft Palate; Cysteine; Female; Folic Acid; Genetic Predisposition to Disease; Genetic Variation; Haplotypes; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Norway; Oxidoreductases Acting on CH-NH Group Donors; Polymerase Chain Reaction; Registries; Risk Factors; Threonine | 2003 |
Mutational analysis of the human FATE gene in 144 infertile men.
Topics: Adult; Alanine; Amino Acid Sequence; Animals; Arginine; Cysteine; DNA Mutational Analysis; DNA Primers; DNA-Binding Proteins; Exons; Humans; Infertility, Male; Introns; Karyotyping; Male; Molecular Sequence Data; Mutation; Pedigree; Polymerase Chain Reaction; Polymorphism, Genetic; Serine; Threonine; Transcription Factors; X Chromosome | 2003 |
The role of two novel regulatory sites in the activation of the cGMP-dependent protein kinase from Plasmodium falciparum.
Topics: Alanine; Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding, Competitive; Conserved Sequence; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Gene Duplication; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmodium falciparum; Protein Binding; Protozoan Proteins; Recombinant Proteins; Serine; Thionucleotides; Threonine | 2003 |
The Ala45Thr polymorphism of BETA2/NeuroD1 gene and susceptibility to type 2 diabetes mellitus in a Polish population.
Topics: Adult; Alanine; Amino Acid Substitution; Basic Helix-Loop-Helix Transcription Factors; Case-Control Studies; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Islets of Langerhans; Mutation, Missense; Poland; Polymorphism, Genetic; Threonine; Trans-Activators | 2003 |
The mouse Chrna4 A529T polymorphism alters the ratio of high to low affinity alpha 4 beta 2 nAChRs.
Topics: Alanine; Amino Acid Substitution; Animals; Cell Line; Humans; Mice; Mice, Inbred Strains; Polymorphism, Genetic; Protein Binding; Receptors, Nicotinic; Threonine | 2003 |
Activity-dependent remodeling of presynaptic inputs by postsynaptic expression of activated CaMKII.
Topics: Alanine; Anesthetics, Local; Animals; Animals, Newborn; Aspartic Acid; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Count; Cell Surface Extensions; Cerebral Cortex; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Gene Expression Regulation, Enzymologic; Green Fluorescent Proteins; Immunohistochemistry; Luminescent Proteins; Lysine; Mutation; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Organ Culture Techniques; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Rats, Long-Evans; Synapses; Synapsins; Synaptic Transmission; Tetrodotoxin; Threonine; Transfection; Valine | 2003 |
The association of Ala54Thr variant of intestinal fatty acid binding protein gene with general and regional adipose tissue depots.
Topics: Adipose Tissue; Aged; Alanine; Asian People; Body Mass Index; Carrier Proteins; Codon; Diabetes Mellitus, Type 2; Fatty Acid-Binding Proteins; Female; Gene Frequency; Genetic Variation; Genotype; Humans; Male; Middle Aged; Threonine | 1999 |
Concerted motions of the integrin-binding loop and the C-terminal tail of the non-RGD disintegrin obtustatin.
Topics: Alanine; Amino Acid Motifs; Collagen; Hydrogen Bonding; Integrin alpha1beta1; Integrins; Magnetic Resonance Spectroscopy; Models, Molecular; Models, Statistical; Peptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serine; Threonine; Viper Venoms | 2003 |
The Ala45Thr polymorphism of BETA2/NeuroD1 gene and susceptibility to type 1 diabetes mellitus in caucasians.
Topics: Adult; Age of Onset; Alanine; Amino Acid Substitution; Base Sequence; Basic Helix-Loop-Helix Transcription Factors; Case-Control Studies; Diabetes Mellitus, Type 1; DNA Primers; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Genotype; Humans; Male; Middle Aged; Polymorphism, Genetic; Reference Values; Threonine; Trans-Activators; White People | 2003 |
Apolipoprotein E -491 promoter polymorphism is an independent risk factor for Alzheimer's disease in the Chinese population.
Topics: Aged; Alanine; Alleles; Alzheimer Disease; Apolipoproteins E; Asian People; Case-Control Studies; Chi-Square Distribution; Cohort Studies; Diagnostic and Statistical Manual of Mental Disorders; DNA Mutational Analysis; Exons; Female; Gene Frequency; Genetic Linkage; Genotype; Humans; Linkage Disequilibrium; Male; Polymerase Chain Reaction; Polymorphism, Genetic; Promoter Regions, Genetic; Risk Factors; Threonine | 2003 |
The nutrition of animal tissues cultivated in vitro. IV. Amino acid requirements of chick embryonic heart fibroblasts.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Fibroblasts; Glycine; Histidine; Hydroxyproline; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
The amino acid requirements of rabbit fibroblasts, strain RM3-56.
Topics: Alanine; Amino Acids; Animals; Arginine; Cystine; Fibroblasts; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Rabbits; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
[Contributions to silkworm biochemistry. XVI. Conversion of threonine into the glycine, serine and alanine of silk fibroin].
Topics: Alanine; Amino Acids; Animals; Bombyx; Fibroins; Glycine; Insecta; Proteins; Serine; Silk; Threonine | 1960 |
Amino acids, amino sugars and sugars present in the cell wall of some strains of Streptococcus pyogenes.
Topics: Alanine; Amino Acids; Amino Sugars; Arginine; Aspartic Acid; Cell Wall; Cysteine; Glucosamine; Glutamates; Glycine; Hexosamines; Isoleucine; Leucine; Lysine; Serine; Streptococcus pyogenes; Threonine; Valine | 1962 |
[On amino acid metabolism in blood diseases with special reference to aplastic anemia].
Topics: Alanine; Amino Acids; Anemia; Anemia, Aplastic; Glutamates; Glycine; Humans; Hydroxyproline; Serine; Threonine | 1962 |
Nematode biochemistry. II. Biosynthesis of amino acids.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Nematoda; Serine; Threonine; Tyrosine; Valine | 1962 |
Protoplast membrane of Streptococcus faecalis.
Topics: Alanine; Amino Acids; Aspartic Acid; Cell Membrane; Enterococcus faecalis; Muramidase; Protoplasts; Threonine; Valine | 1963 |
[MECHANISMS OF AMINO ACID SYNTHESIS IN LEAVES. STUDIES USING RADIOCARBON].
Topics: Alanine; Amino Acids; Aminobutyrates; Ammonium Compounds; Asparagine; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Chromatography; Darkness; Glutamates; Glutamine; Glycine; Light; Methionine; Nitrates; Plant Proteins; Proteins; Quaternary Ammonium Compounds; Research; Serine; Threonine | 1963 |
SPECIFICITY OF PEPSIN AND ITS DEPENDENCE ON A POSSIBLE 'HYDROPHOBICBINDING SITE'.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pepsin A; Peptides; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
[CONVERSION OF THREONINE AND ALANINE IN EXTRACTS OF FLEXNER AND SONNE DYSENTERIAL BACTERIA].
Topics: Alanine; Bacteria; Research; Shigella; Threonine | 1963 |
GAS CHROMATOGRAPHY OF AMINO ACIDS. 1. ANALYSIS OF THE MIXTURE OF METHYL-NTRIFLUOROACETYL DERIVATIVES.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography; Chromatography, Gas; Fluoroacetates; Glutamates; Glycine; Hydroxyproline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1963 |
THE NH2-TERMINAL RESIDUES OF THE PROTEINS FROM CELL-FREE EXTRACTS OF E. COLI.
Topics: Alanine; Aspartic Acid; Bacterial Proteins; Chromatography; Electrophoresis; Escherichia coli; Glutamates; Methionine; Phenytoin; Proteins; Research; Serine; Threonine | 1963 |
EFFECT OF ALANINE AND THREONINE ON THE SYNTHESIS OF SERINE BY LEUCONOSTOC MESENTEROIDES.
Topics: Alanine; Amino Acids; Bacterial Proteins; Benzoates; Formates; Glutamine; Glycine; Histidine; Leuconostoc; Leucovorin; Proteins; Research; Serine; Threonine | 1963 |
THE SOLUBILITY OF AMINO ACIDS AND RELATED COMPOUNDS IN AQUEOUS UREA SOLUTIONS.
Topics: Alanine; Amino Acids; Asparagine; Chemical Phenomena; Chemistry; Glutamine; Glycine; Histidine; Leucine; Methionine; Peptides; Phenylalanine; Research; Solubility; Solvents; Spectrophotometry; Threonine; Tryptophan; Tyrosine; Urea | 1963 |
THE INHIBITION OF CEREBRAL DIGLYCINASE BY ALPHA-AMINO-, ALPHA-KETO- AND ALPHA-HYDROXY ACIDS.
Topics: Alanine; Aminobutyrates; Animals; Arginine; Aspartic Acid; Brain; Cobalt; Enzyme Inhibitors; Histidine; Hydroxy Acids; Keto Acids; Leucine; Methionine; Mice; Peptide Hydrolases; Peptides; Pharmacology; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Valine | 1963 |
OXIDATION OF L-AMINO ACIDS AND INCORPORATION INTO PROTEIN IN HOMOGENATES OF BRAIN AT TWO STAGES OF DEVELOPMENT.
Topics: Alanine; Amino Acids; Arginine; Autoradiography; Brain; Carbon Isotopes; Chromatography; Glycine; Histidine; Isoleucine; Keto Acids; Leucine; Lysine; Mice; Nerve Tissue Proteins; Phenylalanine; Proline; Proteins; Pyruvates; Research; Serine; Threonine; Valine | 1963 |
[ON THE QUANTITATIVE DETERMINATION OF AMINO ACIDS USING HIGH VOLTAGE ELECTROPHORESIS].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Blood Protein Electrophoresis; Glutamates; Histidine; Leucine; Lysine; Methionine; Ornithine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
[CONTRIBUTION TO THE STUDY OF RIBONUCLEOPROTEINS OF NORMAL AND NEOPLASTIC TISSUES].
Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Isoleucine; Leucine; Liver; Lysine; Mice; Neoplasm Proteins; Neoplasms; Nucleoproteins; Phenylalanine; Rats; Research; Ribonucleoproteins; RNA; RNA, Neoplasm; Serine; Threonine; Tyrosine; Valine | 1963 |
BIOCHEMISTRY OF LUNGS IN RELATION TO SILICOSIS. II. THE EFFECT OF QUARTZ DUST ON THE PROTEIN AMINO ACIDS OF GUINEA PIG LUNG TISSUE.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Collagen; Cystine; Dust; Glutamates; Glycine; Guinea Pigs; Histidine; Hydroxyproline; Isoleucine; Leucine; Lung; Lysine; Methionine; Phenylalanine; Proline; Quartz; Research; Serine; Silicon Dioxide; Silicosis; Threonine; Toxicology; Tyrosine; Valine | 1964 |
THE SUBMOLAR QUANTITIES OF N-TERMINALS IN PROTEINS. EFFECT OF SODIUM DODECYL SULFATE ON THE N-TERMINALS OF EGG ALBUMIN AND BOVINE, EQUINE, AND PORCINE GAMMA-GLOBULINS.
Topics: Alanine; Albumins; Animals; Cattle; Chemistry Techniques, Analytical; gamma-Globulins; Glutamates; Horses; Ovalbumin; Proteins; Research; Serine; Sodium Dodecyl Sulfate; Surface-Active Agents; Swine; Threonine; Trypsin | 1964 |
[ON THE EFFECT OF EXPERIMENTALLY INDUCED CONVULSIONS ON THE PERMEABILITY OF THE HEMATOENCEPHALIC BARRIER TO VARIOUS AMINO ACIDS].
Topics: Alanine; Amino Acids; Blood Chemical Analysis; Blood-Brain Barrier; Cerebrospinal Fluid; Chemical Phenomena; Chemistry; Dogs; Glutamates; Glycine; Permeability; Research; Seizures; Threonine; Valine | 1963 |
THE INCORPORATION OF LABELLED CO2 INTO CELLS AND EXTRACTS OF NITROSOMONAS EUROPAEA.
Topics: Adenosine Triphosphate; Alanine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Glycine; Heptoses; Hexoses; Metabolism; NAD; Nitrosomonas; Nitrosomonas europaea; Phosphates; Pyruvates; Research; Serine; Threonine | 1964 |
MIGRATION OF AMINO ACIDS ACROSS THE MEMBRANE OF THE HUMAN ERYTHROCYTE.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport; Carbon Isotopes; Erythrocytes; Glycine; Histidine; Leucine; Methionine; Permeability; Phenylalanine; Proteins; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
DYNAMIC PHENOMENA IN MICROSPHERES FROM THERMAL PROTEINOID.
Topics: Alanine; Arginine; Aspartic Acid; Colloids; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Microspheres; Peptides; Phenylalanine; Photomicrography; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
[SEPARATION OF AMINO ACIDS BY CHROMATOGRAPHY ON THIN LAYERS OF DIETHYLAMINOETHYL CELLULOSE].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
THE INHIBITION OF MITOCHONDRIAL ADENOSINE TRIPHOSPHATASE. 2. THE EFFECTS OF AMINO ACIDS AND SUGARS.
Topics: Adenosine Triphosphatases; Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Enzyme Inhibitors; Fructose; Glutamates; Glycine; Histidine; Hydroxyproline; Isoleucine; Lactose; Liver; Lysine; Methionine; Mitochondria; Oligosaccharides; Pharmacology; Proline; Rats; Research; Serine; Threonine; Valine | 1964 |
AMINO ACID METABOLISM IN RAT BRAIN STUDIED WITH 14C-LABELLED GLUCOSE.
Topics: Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Brain; Carbon Isotopes; Glucose; Glutamates; Glutamine; Glycine; Lead; Nitrophenols; Proteins; Rats; Research; Seizures; Serine; Threonine; Tin; Toxicology | 1964 |
CHROMATOGRAPHIC SEPARATION OF PYRIDOXYL DERIVATIVES OF AMINO ACIDS.
Topics: Alanine; Amines; Amino Acids; Arginine; Aspartic Acid; Chromatography; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Phenylalanine; Pyridines; Pyridoxine; Research; Serine; Threonine; Tyrosine; Valine | 1964 |
SERUM AMINO ACIDS IN KWASHIORKOR. I. RELATIONSHIP TO CLINICAL CONDITION.
Topics: Alanine; Amino Acids; Biomedical Research; Black People; Blood; Glutamates; Glutamine; Glycine; Infant; Isoleucine; Kwashiorkor; Leucine; Methionine; Phenylalanine; Serine; Threonine; Tyrosine; Uganda; Valine | 1964 |
[FREE AMINO ACIDS IN THE BLOOD AND URINE OF PATIENTS WITH SOME FORMS OF DERMATOSIS].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Blood; Cystine; Dermatitis; Eczema; Erythema Multiforme; Glutamates; Glycine; Histidine; Lupus Erythematosus, Systemic; Lysine; Proteins; Psoriasis; Renal Aminoacidurias; Serine; Skin Diseases; Taurine; Threonine; Toxicology; Tryptophan; Urticaria | 1964 |
[ON THE HORMONAL REGULATION OF PROTEIN METABOLISM. THE EFFECT ON INSULIN AND GLUCAGON].
Topics: Alanine; Arginine; Aspartic Acid; Blood Glucose; Carbohydrate Metabolism; Glucagon; Glutamates; Glycine; Histidine; Insulin; Leucine; Lysine; Pharmacology; Phenylalanine; Proteins; Threonine; Tyrosine; Valine | 1964 |
THE ENZYMATIC SYNTHESIS OF D-ALANYL-D-ALANINE. 3. ON THE INHIBITION OF D-ALANYL-D-ALANINE SYNTHETASE BY THE ANTIBIOTIC D-CYCLOSERINE.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Anti-Bacterial Agents; Carbon Isotopes; Chromatography; Cycloserine; Enterococcus faecalis; Enzyme Inhibitors; Ligases; Magnesium; Oxazoles; Pharmacology; Potassium; Research; Serine; Threonine | 1964 |
[ON THE COLORIMETRY OF ALPHA-AMINO ACIDS AND PRIMARY AMINES WITH THE AID OF ASCORBIC ACID].
Topics: Alanine; Amines; Amino Acids; Ammonia; Ascorbic Acid; Colorimetry; Ethylamines; Glutamates; Glycine; Histidine; Lysine; Methionine; Research; Spectrophotometry; Threonine; Tryptophan | 1964 |
INOTROPIC ACTIVITY OF A SERIES OF AMINO ACIDS.
Topics: Adrenal Glands; Alanine; Amino Acids; Blood Pressure; Cysteine; Dogs; Glycine; Heart; Leucine; Methionine; Pharmacology; Research; Sensory Receptor Cells; Serine; Threonine | 1964 |
STUDIES ON THE HYDROLYTIC ACTION OF PRONASE ON DERIVATIZED AND NON-DERIVATIZED PROTEINS.
Topics: Alanine; Arginine; Asparagine; Cystine; Dinitrophenols; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptide Hydrolases; Phenylalanine; Proline; Pronase; Proteins; Research; Ribonucleases; Streptomyces; Threonine; Tyrosine; Valine | 1964 |
EVALUATION OF THE AMINO ACID EXCRETION PATTERN OF MENTAL RETARDATES AS A SCREENING TECHNIQUE FOR INBORN ERRORS OF METABOLISM.
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Child; Chromatography; Creatine; Creatinine; Cystine; Glutamates; Glutamine; Glycine; Humans; Infant; Intellectual Disability; Mass Screening; Renal Aminoacidurias; Threonine | 1964 |
AMINO ACID COMPOSITION OF BULK PROTEIN OF EUGLENA GROWN IN WASTE WATER.
Topics: Alanine; Amino Acids; Animals; Euglena; Histidine; Methionine; Proline; Proteins; Research; Sewage; Threonine; Tryptophan; Valine; Wastewater | 1964 |
[FREE PLASMA AMINO ACIDS IN LIVER CIRRHOSIS AND HEPATITIS].
Topics: Alanine; Amino Acids; Blood; Chromatography; Glutamine; Glycine; Hepatitis; Humans; Ion Exchange Resins; Liver Cirrhosis; Methionine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine | 1964 |
MYOGLOBIN FREE-RADICALS.
Topics: Alanine; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Glycine; Histidine; Hydrogen Peroxide; Leucine; Myoglobin; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
SOME PROPERTIES OF METHANOBACTERIUM OMELIANSKII FERREDOXIN.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacteria; Chemistry Techniques, Analytical; Cystine; Ferredoxins; Glutamates; Glycine; Iron; Lysine; Methanobacterium; Proline; Serine; Spectrophotometry; Sulfides; Threonine; Tyrosine; Valine | 1964 |
LIQUID-LIQUID EXTRACTION IN THE AUTOANALYZER. DETERMINATION OF TAURINE.
Topics: Adrenalectomy; Alanine; Autoanalysis; Automation; Chemistry Techniques, Analytical; Chloroform; Glycine; Liquid-Liquid Extraction; Rats; Research; Serine; Sulfonic Acids; Taurine; Threonine | 1964 |
AMINO ACIDS AS PROTECTIVE COMPOUNDS IN ULTRAVIOLET-IRRADIATED HANSENULA WINGEI.
Topics: Alanine; Amino Acids; Arginine; Cysteine; Cystine; Ethionine; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Pichia; Proline; Radiation-Protective Agents; Research; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays; Valine; Yeasts | 1964 |
SUPPRESSION OF THE INHIBITORY ACTION OF GUANIDINE ON VIRUS MULTIPLICATION BY SOME AMINO ACIDS.
Topics: Alanine; Albumins; Amino Acids; Animals; Cattle; Enterovirus; Foot-and-Mouth Disease Virus; Guanidine; Guanidines; Kidney; Leucine; Methionine; Pharmacology; Protein Hydrolysates; Research; Serine; Threonine; Valine | 1964 |
THREONINE AND SERINE LINKAGES IN MUCOPOLYSACCHARIDES AND GLYCOPROTEINS.
Topics: Alanine; Aminobutyrates; Animals; Cattle; Chemical Phenomena; Chemistry; Glycoproteins; Glycosaminoglycans; Serine; Sharks; Threonine | 1964 |
A SIMPLIFIED METHOD FOR THE DETERMINATION OF ISOLEUCINE AND ITS SIX-CARBON PRECURSORS.
Topics: Alanine; Amino Acids; Aminobutyrates; Bacillus subtilis; Carbon; Escherichia coli; Fatty Acids; Hydroxybutyrates; Isoleucine; Keto Acids; Leucine; Lysine; Methionine; Research; Threonine; Valine | 1964 |
DILUTE ACID HYDROLYSIS OF PAPAIN. KINETIC STUDIES AND PEPTIDES FROM THE CARBOXYMETHYLATED PROTEIN.
Topics: Alanine; Aspartic Acid; Chromatography; Electrophoresis; Glutamates; Glycine; Hydrolysis; Kinetics; Papain; Peptides; Proteins; Research; Serine; Spectrophotometry; Threonine | 1965 |
GAS CHROMATOGRAPHY OF VOLATILE AMINO ACID DERIVATIVES. I. ALANINE, GLYCINE, VALINE, LEUCINE, ISOLEUCINE, SERINE AND THREONINE.
Topics: Alanine; Arginine; Chromatography; Chromatography, Gas; Equipment and Supplies; Glycine; Isoleucine; Leucine; Research; Serine; Threonine; Valine | 1965 |
RAT LIVER ENZYME DOES NOT ACTIVATE ACETYLAMINO ACIDS.
Topics: Acetates; Adenosine Triphosphate; Alanine; Amino Acids; Arginine; Diphosphates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Liver; Lysine; Methionine; Phenylalanine; Proline; Rats; Research; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
EFFECT OF AMINO ACIDS ON GROWTH OF SPHAEROTILUS DISCOPHORUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Bacteriological Techniques; Caseins; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Proline; Research; Serine; Sphaerotilus; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
STUDIES ON HUMAN ANTIBODIES. 3. AMINO ACID COMPOSITION OF FOUR ANTIBODIES FROM ONE INDIVIDUAL.
Topics: Alanine; Amino Acids; Antibodies; Arginine; Aspartic Acid; Chemistry Techniques, Analytical; gamma-Globulins; Glutamates; Glycine; Histidine; Immunochemistry; Immunoglobulins; Isoleucine; Leucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1965 |
DECREASE IN APPETITE AND BIOCHEMICAL CHANGES IN AMINO ACID IMBALANCE IN THE RAT.
Topics: Alanine; Amino Acids; Appetite; Biochemical Phenomena; Biochemistry; Diet; Dietary Proteins; Glutamates; Glutens; Isoleucine; Kwashiorkor; Leucine; Liver; Lysine; Muscles; Proline; Rats; Research; Serine; Threonine; Valine | 1965 |
ENZYMIC INCORPORATION OF RIBONUCLEOTIDES AND AMINO ACIDS INTO TRANSFER RIBONUCLEIC ACID.
Topics: Alanine; Alkaline Phosphatase; Amino Acids; Carbon Isotopes; Cytosine Nucleotides; Enzymes; Escherichia coli; Leucine; Ligases; Liver; Microsomes; Nucleotides; Proteins; Radiometry; Rats; Research; Ribonucleotides; Ribosomes; RNA; RNA, Transfer; Threonine | 1965 |
BITTER PEPTIDE ISOLATED FROM MILK CULTURES OF STREPTOCOCCUS CREMORIS.
Topics: Alanine; Amino Acids; Arginine; Butanones; Carboxypeptidases; Chemical Phenomena; Chemistry; Chemistry Techniques, Analytical; Chromatography; Culture Media; Electrophoresis; Glutamates; Glycine; Histidine; Indicators and Reagents; Isoleucine; Leucine; Lysine; Metabolism; Methionine; Milk; Peptide Hydrolases; Peptides; Phenylalanine; Proline; Research; Streptococcus; Threonine; Tyrosine; Valine | 1965 |
Chromatographic studies on urinary excretion patterns in monozygotic and dizygotic twins. I. Methods and analysis.
Topics: Alanine; Chromatography; Glutamine; Glycine; Humans; Threonine; Twins; Twins, Dizygotic; Urine | 1955 |
Methylenetetrahydrofolate reductase gene polymorphisms in patients with schizophrenia.
Topics: Alanine; Alleles; Chi-Square Distribution; Cysteine; DNA Mutational Analysis; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Lymphocytes; Methylenetetrahydrofolate Reductase (NADPH2); Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Schizophrenia; Threonine | 2003 |
Allelic variants of the tryptophan hydroxylase (A218C) and serotonin 1B receptor (A-161T) and personality traits.
Topics: Adult; Alanine; Alleles; Cysteine; Female; Genetic Variation; Genotype; Humans; Male; Middle Aged; Personality; Polymerase Chain Reaction; Polymorphism, Genetic; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Surveys and Questionnaires; Threonine; Tryptophan Hydroxylase | 2003 |
Ser-64 and Ser-111 in PHAS-I are dispensable for insulin-stimulated dissociation from eIF4E.
Topics: Adaptor Proteins, Signal Transducing; Alanine; Binding Sites; Carrier Proteins; Cell Cycle Proteins; Cell Line; DNA, Complementary; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factors; Genetic Vectors; Humans; Insulin; Mutation; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Structure, Tertiary; Serine; Sirolimus; Threonine; Transfection | 2003 |
The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5.
Topics: Acetylglucosamine; Active Transport, Cell Nucleus; Alanine; Animals; Cell Differentiation; Cell Division; Cell Line; Cell Nucleus; CREB-Binding Protein; Cytoplasm; Dimerization; DNA-Binding Proteins; Epithelial Cells; Galactosyltransferases; Glycosylation; Growth Substances; Humans; Insecta; Interferons; Lectins; Ligands; Luciferases; Mass Spectrometry; Microscopy, Fluorescence; Milk Proteins; Mutation; Nuclear Proteins; Phosphorylation; Prolactin; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Serine; STAT5 Transcription Factor; Threonine; Trans-Activators; Transcription, Genetic; Transfection; Tumor Suppressor Proteins; Tyrosine | 2004 |
N-terminal modifications increase the neutral-pH stability of pepsin.
Topics: Alanine; Amino Acid Substitution; Animals; Catalysis; Circular Dichroism; Enzyme Activation; Enzyme Stability; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Lysine; Mutagenesis, Site-Directed; Pepsin A; Pepsinogen A; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Structure-Activity Relationship; Substrate Specificity; Swine; Threonine | 2003 |
Functional characterization and cold sensitivity of T1313A, a new mutation of the skeletal muscle sodium channel causing paramyotonia congenita in humans.
Topics: Adult; Alanine; Amino Acid Substitution; Cell Line; Cold Temperature; Electrophysiology; Female; Humans; Kinetics; Muscle, Skeletal; Mutation, Missense; Myotonic Disorders; NAV1.4 Voltage-Gated Sodium Channel; Pedigree; Phenotype; Sodium Channels; Temperature; Threonine; Time Factors | 2004 |
Hydrogen bonding alteration of Thr-204 in the complex between pharaonis phoborhodopsin and its transducer protein.
Topics: Alanine; Amino Acid Substitution; Archaeal Proteins; Carotenoids; Deuterium Oxide; Halorhodopsins; Hydrogen Bonding; Natronobacterium; Phenylalanine; Photoreceptors, Microbial; Sensory Rhodopsins; Serine; Spectroscopy, Fourier Transform Infrared; Threonine; Tyrosine | 2003 |
Variation in the FABP2 promoter affects gene expression: implications for prior association studies.
Topics: Alanine; Alleles; Amino Acid Substitution; Caco-2 Cells; Carrier Proteins; DNA; Fatty Acid-Binding Proteins; Gene Expression; Genotype; Haplotypes; Humans; Indians, North American; Luciferases; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Recombinant Fusion Proteins; Threonine; Transfection; White People | 2004 |
Association of the (TAAAA)n repeat polymorphism in the sex hormone-binding globulin (SHBG) gene with polycystic ovary syndrome and relation to SHBG serum levels.
Topics: Adult; Alanine; Alleles; DNA; Female; Gene Frequency; Genotype; Humans; Obesity; Polycystic Ovary Syndrome; Polymorphism, Genetic; Repetitive Sequences, Nucleic Acid; Sequence Analysis, DNA; Sex Hormone-Binding Globulin; Tandem Repeat Sequences; Threonine | 2003 |
Analysis of genetic variations of protein tyrosine kinase fyn and their association with alcohol dependence in two independent cohorts.
Topics: 5' Untranslated Regions; Adult; Alanine; Alcoholism; Case-Control Studies; Chi-Square Distribution; Cohort Studies; Cysteine; Female; Gene Frequency; Genetic Variation; Genotype; Glycine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Threonine | 2003 |
Autophosphorylation of a newly identified site of Aurora-B is indispensable for cytokinesis.
Topics: Alanine; Amino Acid Sequence; Animals; Aurora Kinase B; Aurora Kinases; Binding Sites; Cell Division; Cell Nucleus; Chromosomes; COS Cells; HeLa Cells; Histones; Humans; Mass Spectrometry; Microscopy, Fluorescence; Mitosis; Molecular Sequence Data; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Serine-Threonine Kinases; Sequence Homology, Amino Acid; Threonine; Time Factors; Transfection; Vimentin | 2004 |
Association study of onset age, attempted suicide, aggressive behavior, and schizophrenia with a serotonin 1B receptor (A-161T) genetic polymorphism.
Topics: Adult; Age of Onset; Aggression; Alanine; Case-Control Studies; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Polymorphism, Genetic; Receptor, Serotonin, 5-HT1B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Schizophrenia; Schizophrenic Psychology; Suicide, Attempted; Threonine | 2004 |
Support for RGS4 as a susceptibility gene for schizophrenia.
Topics: Adult; Alanine; Alleles; Case-Control Studies; Chi-Square Distribution; Diagnostic and Statistical Manual of Mental Disorders; Female; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Linkage Disequilibrium; Male; Middle Aged; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; RGS Proteins; RNA, Messenger; Schizophrenia; Threonine | 2004 |
Crystallographic studies on structural features that determine the enzymatic specificity and potency of human angiogenin: Thr44, Thr80, and residues 38-41.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Cattle; Crystallization; Crystallography, X-Ray; Evolution, Molecular; Humans; Kinetics; Molecular Sequence Data; Peptide Fragments; Recombinant Fusion Proteins; Ribonuclease, Pancreatic; Structure-Activity Relationship; Substrate Specificity; Threonine | 2004 |
Crystal structure of a cAMP-dependent protein kinase mutant at 1.26A: new insights into the catalytic mechanism.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Cyclic AMP-Dependent Protein Kinases; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Peptide Fragments; Threonine; Tyrosine | 2004 |
Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25.
Topics: Alanine; Animals; Blotting, Western; Calcineurin; Calcium; Carbazoles; Carrier Proteins; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Exocytosis; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Kidney; Membrane Potentials; Membrane Proteins; Models, Biological; Mutation; Nerve Tissue Proteins; Patch-Clamp Techniques; Peptide Fragments; Phosphorylation; Photolysis; Pyrethrins; Pyrroles; Secretory Vesicles; Synaptosomal-Associated Protein 25; Threonine; Time Factors; Transfection | 2004 |
Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands.
Topics: Alanine; Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cycloserine; Databases as Topic; Escherichia coli; Excitatory Amino Acid Antagonists; Glycine; Humans; Hydrogen Bonding; Indoles; Kynurenic Acid; Ligands; Mice; Models, Chemical; Models, Molecular; Molecular Sequence Data; Potassium Channels; Proline; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sequence Homology, Amino Acid; Serine; Threonine; Tryptophan; Water | 2004 |
Role of active-site residues Thr81, Ser82, Thr85, Gln157, and Tyr158 in yeast cystathionine beta-synthase catalysis and reaction specificity.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Catalysis; Chromatography, Affinity; Cystathionine beta-Synthase; Glutamine; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Nickel; Phenylalanine; Pyruvic Acid; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity; Threonine; Tyrosine | 2004 |
Novel activating and inactivating mutations in the integrin beta1 subunit A domain.
Topics: Alanine; Amino Acid Substitution; Animals; Cell Line; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Humans; Integrin beta1; Mutagenesis, Site-Directed; Mutation; Peptides; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Threonine; Transfection; Valine | 2004 |
JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD.
Topics: Alanine; Animals; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Carrier Proteins; Cell Line; Cell Survival; Interleukin-3; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Threonine | 2004 |
Distinct domains of the mu-opioid receptor control uncoupling and internalization.
Topics: Alanine; Amino Acid Substitution; Animals; Arrestin; Cells, Cultured; G Protein-Coupled Inwardly-Rectifying Potassium Channels; G-Protein-Coupled Receptor Kinase 3; Green Fluorescent Proteins; Humans; Luminescent Proteins; Morphine; Oocytes; Phagocytosis; Phosphorylation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Receptors, Opioid, mu; Threonine; Xenopus laevis | 2004 |
Resonance Raman spectroscopy reveals the origin of an intermediate wavelength form in photoactive yellow protein.
Topics: Alanine; Amino Acid Substitution; Bacterial Proteins; Deuterium Exchange Measurement; Glutamic Acid; Glutamine; Kinetics; Phenylalanine; Photoreceptors, Microbial; Quantum Theory; Recombinant Proteins; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Thermodynamics; Thiocyanates; Threonine; Tyrosine; Valine | 2004 |
Intestinal FABP2 A54T polymorphism: association with insulin resistance and obesity in women.
Topics: Adult; Alanine; Alleles; Body Mass Index; Carrier Proteins; Fatty Acid-Binding Proteins; Female; Gene Frequency; Genotype; Humans; Insulin Resistance; Middle Aged; Obesity; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Threonine; Tumor Necrosis Factor-alpha | 2004 |
The C-terminal domain is the primary determinant of histone H1 binding to chromatin in vivo.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line, Tumor; Chromatin; Gene Deletion; Glutamic Acid; Green Fluorescent Proteins; Histones; Humans; Kinetics; Luminescent Proteins; Lysine; Mice; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Point Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Spectrometry, Fluorescence; Threonine; Time Factors; Transfection | 2004 |
Novel reversible inactivation of cytochrome P450 2E1 T303A by tert-butyl acetylene: the role of threonine 303 in proton delivery to the active site of cytochrome P450 2E1.
Topics: Acetylene; Alanine; Alkynes; Animals; Binding Sites; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Enzyme Inhibitors; Mutation; Protons; Rabbits; Spectrometry, Mass, Electrospray Ionization; Threonine | 2004 |
Phosphorylated p40PHOX as a negative regulator of NADPH oxidase.
Topics: Alanine; Animals; Cell Separation; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Enzyme Inhibitors; Humans; Mutagenesis, Site-Directed; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Serine; Sodium Dodecyl Sulfate; Threonine | 2004 |
A novel mutation, Thr65Ala, in the MPZ gene in a patient with Charcot-Marie-Tooth type 1B disease with focally folded myelin.
Topics: Adult; Alanine; Charcot-Marie-Tooth Disease; DNA Mutational Analysis; Female; Hand Deformities; Humans; Microscopy, Electron; Muscular Atrophy; Mutation; Myelin P0 Protein; Myelin Sheath; Protein Folding; Threonine | 2004 |
Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression.
Topics: Alanine; Amino Acid Substitution; Antineoplastic Agents; Apigenin; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; DNA Damage; Drug Stability; Flavonoids; G1 Phase; Histone Acetyltransferases; Humans; Nuclear Proteins; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; RNA, Small Interfering; TATA-Binding Protein Associated Factors; Threonine; Transcription Factor TFIID; Transfection; Tumor Suppressor Protein p53 | 2004 |
A coding mutation within the first exon of the human MD-2 gene results in decreased lipopolysaccharide-induced signaling.
Topics: Alanine; Antigens, Surface; Humans; Lipopolysaccharides; Lymphocyte Antigen 96; Membrane Glycoproteins; Mutation; NF-kappa B; Receptors, Cell Surface; Signal Transduction; Temperature; Threonine; Toll-Like Receptor 4; Toll-Like Receptors; Tumor Necrosis Factor-alpha | 2004 |
Possible association of interleukin 1 gene locus polymorphisms with low back pain.
Topics: Adult; Alanine; Alleles; Cohort Studies; Cysteine; Finland; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Interleukin-1; Intervertebral Disc Displacement; Low Back Pain; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Middle Aged; Pain Measurement; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, Interleukin; Regression Analysis; Risk; RNA; Surveys and Questionnaires; Threonine | 2004 |
Effects of Parkinson's disease-linked mutations on the structure of lipid-associated alpha-synuclein.
Topics: Alanine; alpha-Synuclein; Humans; Lipid Metabolism; Liposomes; Micelles; Mutation, Missense; Nerve Tissue Proteins; Nuclear Magnetic Resonance, Biomolecular; Parkinson Disease; Phosphatidic Acids; Phosphatidylcholines; Proline; Protein Binding; Protein Structure, Secondary; Recombinant Proteins; Synucleins; Threonine | 2004 |
The host cell MAP kinase ERK-2 regulates viral assembly and release by phosphorylating the p6gag protein of HIV-1.
Topics: Alanine; Amino Acid Sequence; Blotting, Western; Cell Line; DNA Mutational Analysis; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; gag Gene Products, Human Immunodeficiency Virus; Gene Products, gag; Glutathione Transferase; HIV-1; Humans; Microscopy, Electron; Mitogen-Activated Protein Kinase 1; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Plasmids; Protein Binding; Protein Structure, Tertiary; RNA, Small Interfering; Sequence Homology, Amino Acid; Threonine; Transfection; Virion; Viruses | 2004 |
Lack of association between Alzheimer's disease and the promoter region polymorphisms of the nicastrin gene.
Topics: Adult; Age of Onset; Aged; Alanine; Alleles; Alzheimer Disease; Amyloid Precursor Protein Secretases; Apolipoproteins E; Cysteine; Female; Gene Frequency; Glycine; Haplotypes; Humans; Logistic Models; Male; Membrane Glycoproteins; Middle Aged; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Threonine | 2004 |
Congenital insensitivity to pain with anhidrosis in Taiwan: a morphometric and genetic study.
Topics: Adolescent; Adult; Alanine; Axons; DNA Mutational Analysis; Electrophysiology; Hereditary Sensory and Autonomic Neuropathies; Humans; Introns; Male; Microscopy, Electron; Mutation; Nerve Fibers, Myelinated; Neural Conduction; Receptor, trkA; Skin; Sural Nerve; Taiwan; Threonine | 2004 |
The critical features and the mechanism of inhibition of a kinase interaction motif-based peptide inhibitor of JNK.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Motifs; Animals; beta-Galactosidase; Binding, Competitive; COS Cells; Databases as Topic; Dose-Response Relationship, Drug; Enzyme Inhibitors; JNK Mitogen-Activated Protein Kinases; Kinetics; Leucine; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Peptides; Plasmids; Proline; Protein Binding; Protein Structure, Tertiary; Temperature; Threonine; Transfection; Two-Hybrid System Techniques | 2004 |
Cysteine-scanning mutagenesis of the fifth external loop of serotonin transporter.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Biological Transport; Carrier Proteins; Cocaine; Cysteine; Dose-Response Relationship, Drug; Epitopes; HeLa Cells; Humans; Ions; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sodium; Threonine | 2004 |
Dynamin GTPase domain mutants that differentially affect GTP binding, GTP hydrolysis, and clathrin-mediated endocytosis.
Topics: Adenoviridae; Alanine; Baculoviridae; Binding Sites; Chromatography, Gel; Clathrin; Dynamins; Endocytosis; GTP Phosphohydrolases; Guanosine Triphosphate; Humans; Hydrolysis; Kinetics; Lipids; Models, Chemical; Mutation; Oligonucleotides; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serine; Temperature; Threonine; Time Factors; Transferrin | 2004 |
The fourth transmembrane domain of the Helicobacter pylori Na+/H+ antiporter NhaA faces a water-filled channel required for ion transport.
Topics: Alanine; Amino Acid Sequence; Antiporters; Aspartic Acid; Binding Sites; Cell Membrane; Cysteine; Cytoplasm; DNA; Escherichia coli; Escherichia coli Proteins; Ethylmaleimide; Helicobacter pylori; Ion Transport; Ions; Kinetics; Leucine; Lithium; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protons; Serine; Sodium-Hydrogen Exchangers; Threonine; Valine; Water | 2004 |
Serine and threonine phosphorylation of the low density lipoprotein receptor-related protein by protein kinase Calpha regulates endocytosis and association with adaptor molecules.
Topics: Adaptor Proteins, Signal Transducing; Alanine; Animals; Cell Line; CHO Cells; COS Cells; Cricetinae; Cytoplasm; DNA Mutational Analysis; Dose-Response Relationship, Drug; Endocytosis; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Glutathione Transferase; Humans; Immunoblotting; Ligands; Low Density Lipoprotein Receptor-Related Protein-1; Mutation; Phosphoamino Acids; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Protein Structure, Tertiary; Proteins; Rats; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Signal Transduction; Threonine; Time Factors; Transfection | 2004 |
A common antitussive drug, clobutinol, precipitates the long QT syndrome 2.
Topics: Alanine; Amino Alcohols; Animals; Antitussive Agents; Arrhythmias, Cardiac; Cation Transport Proteins; Chlorocebus aethiops; COS Cells; Electrophysiology; Ether-A-Go-Go Potassium Channels; Humans; Long QT Syndrome; Male; Mutation; Pedigree; Potassium Channels, Voltage-Gated; Proline; Threonine; Valine | 2004 |
Molecular determinants of frequency dependence and Ca2+ potentiation of verapamil block in the pore region of Cav1.2.
Topics: Alanine; Amino Acid Substitution; Barium; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Drug Synergism; Glutamic Acid; Glutamine; Glycine; Humans; Kinetics; Mutation; Permeability; Phenylalanine; Threonine; Verapamil | 2004 |
Studies of SpoIIAB mutant proteins elucidate the mechanisms that regulate the developmental transcription factor sigmaF in Bacillus subtilis.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Substitution; Arginine; Bacillus subtilis; Bacterial Proteins; Glutamic Acid; Kinetics; Lysine; Multiprotein Complexes; Mutation; Nucleotides; Phenotype; Phosphorylation; Sigma Factor; Threonine | 2004 |
Alanine-threonine polymorphism of Helicobacter pylori RpoB is correlated with differential induction of interleukin-8 in MKN45 cells.
Topics: Alanine; Amino Acid Substitution; Animals; Base Sequence; Cell Line; Coculture Techniques; DNA Primers; DNA-Directed RNA Polymerases; DNA, Bacterial; Geography; Helicobacter pylori; Interleukin-8; Phylogeny; Polymerase Chain Reaction; Threonine | 2004 |
Alpha-synuclein missense and multiplication mutations in autosomal dominant Parkinson's disease.
Topics: Adult; Age Factors; Alanine; alpha-Synuclein; DNA Mutational Analysis; Exons; Family Health; Female; Humans; Male; Middle Aged; Mutation; Nerve Tissue Proteins; Parkinsonian Disorders; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synucleins; Threonine | 2004 |
Genetic variation in apolipoprotein D and Alzheimer's disease.
Topics: Age of Onset; Aged; Alanine; Alzheimer Disease; Apolipoproteins; Apolipoproteins D; Case-Control Studies; Cysteine; Female; Finland; Gene Frequency; Genetic Variation; Genotype; Glycine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Threonine | 2004 |
Metabolic properties of Eubacterium pyruvativorans, a ruminal 'hyper-ammonia-producing' anaerobe with metabolic properties analogous to those of Clostridium kluyveri.
Topics: Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; Caseins; Clostridium; Crotonates; Energy Metabolism; Eubacterium; Fatty Acids, Volatile; Fermentation; Glycine; Lactic Acid; Leucine; Peptides; Proline; Pyruvic Acid; Rumen; Serine; Threonine | 2004 |
The -1438A/G polymorphism in the 5-hydroxytryptamine type 2A receptor gene affects promoter activity.
Topics: Alanine; Cell Line, Tumor; Chloramphenicol O-Acetyltransferase; Cysteine; Genes, Reporter; Glycine; Humans; Linkage Disequilibrium; Neuroblastoma; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Receptor, Serotonin, 5-HT2A; Threonine; Transfection | 2004 |
Association of estrogen receptor alpha polymorphisms with susceptibility to chronic hepatitis B virus infection.
Topics: Adult; Alanine; Alleles; Asian People; Chromosome Mapping; Cysteine; Estrogen Receptor alpha; Female; Genetic Predisposition to Disease; Haplotypes; Hepatitis B, Chronic; Heterozygote; Humans; Linkage Disequilibrium; Male; Middle Aged; Polymorphism, Single Nucleotide; Receptors, Estrogen; Threonine | 2004 |
CYP1A1 variants and smoking-related lung cancer in San Francisco Bay area Latinos and African Americans.
Topics: Aged; Alanine; Black or African American; Case-Control Studies; Confounding Factors, Epidemiologic; Cysteine; Cytochrome P-450 CYP1A1; Female; Genotype; Glycine; Hispanic or Latino; Humans; Linkage Disequilibrium; Lung Neoplasms; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; San Francisco; Smoking; Threonine | 2005 |
Mutation of the putative hydrogen-bond donor to P700 of photosystem I.
Topics: Alanine; Animals; Chlamydomonas reinhardtii; Chlorophyll; Electron Spin Resonance Spectroscopy; Electron Transport; Free Radicals; Hydrogen Bonding; Light-Harvesting Protein Complexes; Mutagenesis, Site-Directed; Oxidation-Reduction; Photosystem I Protein Complex; Plant Proteins; Potentiometry; Protein Processing, Post-Translational; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Threonine; Thylakoids | 2004 |
The vaccinia virus B1R kinase induces p53 downregulation by an Mdm2-dependent mechanism.
Topics: Alanine; Amino Acid Substitution; Animals; Cell Line; Down-Regulation; Mice; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Serine; Threonine; Tumor Suppressor Protein p53; Vaccinia virus; Viral Proteins | 2004 |
Unexpected intracellular localization of the AMD-associated cystatin C variant.
Topics: Aging; Alanine; Blotting, Western; Cell Nucleus; Cells, Cultured; Cystatins; Cytoplasm; DNA Primers; Electrophoresis, Polyacrylamide Gel; Golgi Apparatus; Green Fluorescent Proteins; HeLa Cells; Humans; Macular Degeneration; Microscopy, Confocal; Microscopy, Fluorescence; Mitochondria; Mutagenesis, Site-Directed; Mutation; Pigment Epithelium of Eye; Plant Proteins; Plasmids; Protein Structure, Tertiary; Threonine; Time Factors; Transfection; Trypsin | 2004 |
Familial Alzheimer disease associated with A713T mutation in APP.
Topics: Alanine; Alzheimer Disease; Cerebral Cortex; DNA Mutational Analysis; Exons; Humans; Immunohistochemistry; Male; Middle Aged; Molecular Sequence Data; Point Mutation; Serum Amyloid A Protein; Threonine | 2004 |
No association of the A260G and A386G DAZL single nucleotide polymorphisms with male infertility in a Caucasian population.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Case-Control Studies; Gene Frequency; Genetic Predisposition to Disease; Genetics, Population; Germany; Humans; Infertility, Male; Male; Molecular Sequence Data; Oligospermia; Polymorphism, Single Nucleotide; RNA-Binding Proteins; Spermatozoa; Threonine; White People | 2004 |
Fas gene mutations in mycosis fungoides: analysis of laser capture-microdissected specimens from cutaneous lesions.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Aged, 80 and over; Alanine; Animals; Apoptosis; Aspartic Acid; Carrier Proteins; Co-Repressor Proteins; Codon; DNA, Neoplasm; Female; Humans; Intracellular Signaling Peptides and Proteins; Isoleucine; Laser Therapy; Lymphoma, T-Cell; Male; Mice; Microdissection; Middle Aged; Molecular Chaperones; Mutation, Missense; Mycosis Fungoides; Nuclear Proteins; Signal Transduction; Threonine; Transfection | 2004 |
Ycf1-dependent cadmium detoxification by yeast requires phosphorylation of residues Ser908 and Thr911.
Topics: Alanine; Alkaline Phosphatase; Amino Acid Substitution; ATP-Binding Cassette Transporters; Cadmium; Electrophoretic Mobility Shift Assay; Fungal Proteins; Gene Deletion; Inactivation, Metabolic; Phosphorylation; Point Mutation; Protein Kinases; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine | 2004 |
A CRM1-dependent nuclear export pathway is involved in the regulation of IRF-5 subcellular localization.
Topics: Active Transport, Cell Nucleus; Alanine; Amino Acid Sequence; Blotting, Western; Cell Line; Cell Nucleus; Cytoplasm; DNA Mutational Analysis; DNA-Binding Proteins; Exportin 1 Protein; Genes, Reporter; Green Fluorescent Proteins; Humans; Immunoblotting; Interferon Regulatory Factors; Interferons; Karyopherins; Leucine; Luciferases; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Phosphorylation; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Sequence Homology, Amino Acid; Serine; Threonine; Time Factors; Transcription Factors; Transfection | 2005 |
Interaction between the catalytic site and the A-M3 linker stabilizes E2/E2P conformational states of Na+,K+-ATPase.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Animals; Catalysis; Catalytic Domain; COS Cells; Crystallography, X-Ray; Cytoplasm; Dose-Response Relationship, Drug; Glycine; Hydrolysis; Isoleucine; Kinetics; Ligands; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Ouabain; Phosphorylation; Potassium; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Rubidium; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Threonine; Time Factors; Vanadates | 2005 |
Exacerbated synucleinopathy in mice expressing A53T SNCA on a Snca null background.
Topics: Age Factors; Alanine; alpha-Synuclein; Animals; Behavior, Animal; Blotting, Western; Disease Models, Animal; Glial Fibrillary Acidic Protein; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Motor Activity; Mutation; Nerve Tissue Proteins; Parkinson Disease; Phenylenediamines; RNA; Sciatic Nerve; Spinal Cord; Synucleins; Threonine; Wallerian Degeneration | 2005 |
Saccharomyces cerevisiae Aqr1 is an internal-membrane transporter involved in excretion of amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; beta-Galactosidase; Biological Transport; Cell Membrane; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Endocytosis; Exocytosis; Gene Expression Regulation, Fungal; Genotype; Glutamic Acid; Green Fluorescent Proteins; Homoserine; Membrane Transport Proteins; Methylamines; Microscopy, Fluorescence; Models, Biological; Monocarboxylic Acid Transporters; Mutation; Oligonucleotides; Plasmids; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Threonine; Time Factors | 2004 |
A single nucleotide polymorphism on the promoter of eotaxin1 associates with its mRNA expression and asthma phenotypes.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Amino Acid Substitution; Asthma; Binding Sites; Bronchial Provocation Tests; Chemokine CCL11; Chemokines, CC; Eosinophils; Female; Haplotypes; Humans; Immunoglobulin E; Leukocyte Count; Leukocytes, Mononuclear; Male; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; RNA, Messenger; Threonine; Transcription Factors | 2005 |
Identification of residues that contribute to receptor activation through the analysis of compensatory mutations in the G protein-coupled alpha-factor receptor.
Topics: Alanine; Amino Acid Sequence; Cysteine; DNA Mutational Analysis; Genes, Suppressor; Genetic Testing; Mating Factor; Molecular Sequence Data; Mutagenesis; Peptides; Phenylalanine; Receptors, G-Protein-Coupled; Receptors, Mating Factor; Receptors, Peptide; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Threonine; Transcription Factors; Tyrosine | 2005 |
Renin-angiotensin system and haemostasis gene polymorphisms and outcome after coronary artery bypass graft surgery.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Angiotensinogen; Blood Coagulation; Blood Pressure; Coronary Artery Bypass; Coronary Artery Disease; Cysteine; Factor V; Female; Follow-Up Studies; Genotype; Humans; Integrin beta3; Male; Methionine; Middle Aged; Myocardial Contraction; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Stroke Volume; Threonine; Treatment Outcome | 2005 |
The contribution of C alpha-H...O hydrogen bonds to membrane protein stability depends on the position of the amide.
Topics: Alanine; Amides; Amino Acid Motifs; Bacteriorhodopsins; Carbon; Computer Simulation; Glycophorins; Hydrogen Bonding; Lipid Bilayers; Membrane Proteins; Models, Chemical; Models, Molecular; Oxygen; Protein Structure, Secondary; Thermodynamics; Threonine | 2005 |
Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: enhancing the promiscuous D-arabino-hex-3-ulose 6-phosphate synthase reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase.
Topics: Alanine; Aldehyde-Lyases; Aldehydes; Amino Acid Substitution; Arginine; Aspartic Acid; Carboxy-Lyases; Catalysis; Decarboxylation; Enzyme Stability; Escherichia coli Proteins; Evolution, Molecular; Formaldehyde; Glutamic Acid; Histidine; Ketoses; Methylomonas; Orotidine-5'-Phosphate Decarboxylase; Ribulosephosphates; Stereoisomerism; Threonine; Valine | 2005 |
Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: structural basis for catalytic promiscuity in wild-type and designed mutants of 3-keto-L-gulonate 6-phosphate decarboxylase.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Binding Sites; Carboxy-Lyases; Catalysis; Crystallography, X-Ray; Enzyme Activation; Escherichia coli Proteins; Evolution, Molecular; Glutamic Acid; Mutagenesis, Site-Directed; Orotidine-5'-Phosphate Decarboxylase; Ribulosephosphates; Substrate Specificity; Threonine | 2005 |
An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor.
Topics: Alanine; Amino Acid Motifs; Animals; Asparagine; Aspartic Acid; Binding Sites; Cattle; Cell Membrane; Cell Separation; COS Cells; Cyclic AMP; Dose-Response Relationship, Drug; Flow Cytometry; Hydrogen Bonding; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Receptors, Thyrotropin; Rhodopsin; Software; Static Electricity; Threonine; Transfection | 2005 |
Regulated folding of tyrosinase in the endoplasmic reticulum demonstrates that misfolded full-length proteins are efficient substrates for class I processing and presentation.
Topics: Alanine; Amino Acid Substitution; Animals; Antigen Presentation; Arginine; Cell Line; Cell Line, Tumor; Endoplasmic Reticulum; Epitopes; Glutamine; Histocompatibility Antigens Class I; Intracellular Fluid; Melanoma; Mice; Mice, Inbred C57BL; Monophenol Monooxygenase; Peptide Fragments; Proteasome Endopeptidase Complex; Protein Folding; Protein Processing, Post-Translational; Protein Transport; Substrate Specificity; Threonine; Transfection; Tyrosine | 2005 |
P450 active site architecture and reversibility: inactivation of cytochromes P450 2B4 and 2B4 T302A by tert-butyl acetylenes.
Topics: Alanine; Alkynes; Animals; Aryl Hydrocarbon Hydroxylases; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Cytochrome P450 Family 2; Enzyme Inhibitors; Ethers; Heme; Hydrogen Bonding; Models, Molecular; Oxidants; Peroxides; Rabbits; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Threonine | 2005 |
The type 2 deiodinase A/G (Thr92Ala) polymorphism is associated with decreased enzyme velocity and increased insulin resistance in patients with type 2 diabetes mellitus.
Topics: Alanine; Amino Acid Substitution; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Kinetics; Polymorphism, Single Nucleotide; Threonine | 2005 |
p38 Mitogen-activated protein kinase (MAPK) is a key mediator in glucocorticoid-induced apoptosis of lymphoid cells: correlation between p38 MAPK activation and site-specific phosphorylation of the human glucocorticoid receptor at serine 211.
Topics: Alanine; Animals; Apoptosis; Cell Line; Cell Line, Tumor; Cell Survival; Dexamethasone; DNA; Enzyme Activation; Flow Cytometry; Glucocorticoids; Humans; Immunohistochemistry; Kinetics; Lymphocytes; MAP Kinase Kinase 3; MAP Kinase Signaling System; Mice; Models, Biological; Mutation; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Propidium; Proto-Oncogene Proteins c-myc; Receptors, Glucocorticoid; RNA, Messenger; Serine; Signal Transduction; Threonine; Time Factors; Transcriptional Activation; Transfection | 2005 |
Crystal structures of the ferrous dioxygen complex of wild-type cytochrome P450eryF and its mutants, A245S and A245T: investigation of the proton transfer system in P450eryF.
Topics: Alanine; Bacterial Proteins; Binding Sites; Catalysis; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Hydrogen Bonding; Hydroxylation; Iron; Ligands; Mixed Function Oxygenases; Models, Molecular; Mutation; Oxygen; Protein Binding; Protein Conformation; Protons; Saccharopolyspora; Threonine | 2005 |
A founder mutation in the CLCNKB gene causes Bartter syndrome type III in Spain.
Topics: Adolescent; Alanine; Amino Acid Substitution; Anion Transport Proteins; Bartter Syndrome; Base Sequence; Child; Child, Preschool; Chloride Channels; DNA Mutational Analysis; Founder Effect; Genotype; Homozygote; Humans; Infant; Membrane Proteins; Mutation, Missense; Phenotype; Point Mutation; Spain; Threonine | 2005 |
Molecular genetics of hereditary prothrombin deficiency in Indian patients: identification of a novel Ala362 --> Thr (Prothrombin Vellore 1) mutation.
Topics: Adult; Alanine; Alternative Splicing; Child, Preschool; Codon; DNA; DNA Mutational Analysis; DNA Primers; Evolution, Molecular; Female; Gene Deletion; Heterozygote; Homozygote; Humans; Hypoprothrombinemias; India; Male; Middle Aged; Models, Genetic; Models, Molecular; Mutation; Mutation, Missense; Partial Thromboplastin Time; Protein Conformation; Protein Structure, Tertiary; Prothrombin; Prothrombin Time; Sequence Analysis, DNA; Threonine; Thrombin | 2005 |
Functional analysis of the Ala67Thr polymorphism in agouti related protein associated with anorexia nervosa and leanness.
Topics: Agouti-Related Protein; Alanine; Animals; Anorexia Nervosa; Cell Line; Cricetinae; Dose-Response Relationship, Drug; Eating; Humans; Injections, Intraventricular; Intercellular Signaling Peptides and Proteins; Polymorphism, Genetic; Proteins; Rats; Rats, Wistar; Thinness; Threonine | 2005 |
Analysis of active site residues of botulinum neurotoxin E by mutational, functional, and structural studies: Glu335Gln is an apoenzyme.
Topics: Alanine; Apoenzymes; Arginine; Asparagine; Binding Sites; Botulinum Toxins; Catalysis; Crystallization; Enzyme Activation; Glutamic Acid; Glutamine; Kinetics; Mutagenesis, Site-Directed; Neprilysin; Neurotoxins; Protease Inhibitors; Substrate Specificity; Thermolysin; Threonine; Tyrosine | 2005 |
Effect on DNA relaxation of the single Thr718Ala mutation in human topoisomerase I: a functional and molecular dynamics study.
Topics: Alanine; Amino Acid Substitution; Computer Simulation; DNA; DNA Topoisomerases, Type I; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Mutation; Principal Component Analysis; Threonine | 2005 |
D-Serine uptake by isolated retinas is consistent with ASCT-mediated transport.
Topics: 4-Chloro-7-nitrobenzofurazan; Alanine; Ambystoma; Amino Acid Transport System ASC; Animals; Biological Transport; Cysteine; Electrophoresis, Capillary; In Vitro Techniques; Retina; Serine; Sodium; Threonine; Time Factors | 2005 |
SCN9A mutations define primary erythermalgia as a neuropathic disorder of voltage gated sodium channels.
Topics: Adult; Alanine; Conserved Sequence; Cysteine; Erythromelalgia; Female; Genes, Dominant; Heterozygote; Humans; Male; Mutation; Mutation, Missense; NAV1.7 Voltage-Gated Sodium Channel; Nervous System Diseases; Pedigree; Polymorphism, Genetic; Sodium Channels; Threonine | 2005 |
Versatile and stereoselective syntheses of orthogonally protected beta-methylcysteine and beta-methyllanthionine.
Topics: Alanine; Amino Acid Sequence; Aziridines; Catalysis; Cysteine; Molecular Structure; Stereoisomerism; Sulfides; Threonine | 2005 |
Identification of Ser153 in ICL2 of the gonadotropin-releasing hormone (GnRH) receptor as a phosphorylation-independent site for inhibition of Gq coupling.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; COS Cells; DNA Primers; Epitopes; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gq-G11; Hydrolysis; Immunoblotting; Inositol Phosphates; Kinetics; MAP Kinase Signaling System; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Phosphorylation; Plasmids; Polymerase Chain Reaction; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; Receptors, LHRH; Serine; Threonine; Time Factors; Transfection | 2005 |
Characterization of the replication region of plasmid pLS32 from the Natto strain of Bacillus subtilis.
Topics: Alanine; Bacillus subtilis; Bacterial Proteins; Base Sequence; DNA Replication; Genes, Bacterial; Histidine; Molecular Sequence Data; Mutation; Plasmids; Protein Binding; Replicon; Tandem Repeat Sequences; Threonine; Transcription Initiation Site; Transcription, Genetic | 2005 |
Studies of relationships between the GLUT10 Ala206Thr polymorphism and impaired insulin secretion.
Topics: Adult; Alanine; Blood Glucose; Case-Control Studies; Codon; Cohort Studies; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; Glucose Tolerance Test; Glucose Transport Proteins, Facilitative; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Monosaccharide Transport Proteins; Phenotype; Polymorphism, Genetic; Threonine | 2005 |
Isolation and characterization of hemolymph antifreeze proteins from larvae of the longhorn beetle Rhagium inquisitor (L.).
Topics: Alanine; Amino Acids; Animals; Antifreeze Proteins; Arginine; Cations; Chromatography, Ion Exchange; Coleoptera; Cysteine; Glycine; Hemolymph; Isoelectric Focusing; Larva; Mass Spectrometry; Threonine | 2005 |
Inducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells.
Topics: Adenoviridae; Alanine; Annexin A5; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Doxycycline; Ecdysterone; Humans; Immunoblotting; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Prognosis; Proteasome Endopeptidase Complex; Proteins; S Phase; Threonine; Time Factors; Tumor Suppressor Proteins; Ubiquitin | 2005 |
The common A467T mutation in the human mitochondrial DNA polymerase (POLG) compromises catalytic efficiency and interaction with the accessory subunit.
Topics: Alanine; Amino Acid Substitution; Animals; Catalytic Domain; Cell Line; DNA Polymerase gamma; DNA-Directed DNA Polymerase; DNA, Mitochondrial; Ethylmaleimide; Hot Temperature; Humans; Mutagenesis, Site-Directed; Nucleic Acid Synthesis Inhibitors; Point Mutation; Protein Structure, Quaternary; Spodoptera; Thermolysin; Threonine | 2005 |
The 5alpha-reductase type II A49T and V89L high-activity allelic variants are more common in men with prostate cancer compared with the general population.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aged; Alanine; Alleles; Arginine; Biomarkers, Tumor; Case-Control Studies; Dihydrotestosterone; Disease Progression; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Leucine; Luteinizing Hormone; Male; Middle Aged; Point Mutation; Polymorphism, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen; Risk Factors; Sex Hormone-Binding Globulin; Sweden; Terminal Repeat Sequences; Testosterone; Threonine; Valine | 2005 |
Molecular basis of alanine discrimination in editing site.
Topics: Acylation; Alanine; Amino Acid Sequence; Amino Acyl-tRNA Synthetases; Apoenzymes; Bacterial Proteins; Binding Sites; Dimerization; Humans; Models, Molecular; Molecular Sequence Data; Protein Structure, Quaternary; Pyrococcus horikoshii; RNA Editing; RNA, Transfer, Ala; Sequence Alignment; Serine; Substrate Specificity; Threonine; Zinc | 2005 |
The prevalence of C807T mutation of glycoprotein Ia gene among young male survivors of myocardial infarction: a relation with coronary angiography results.
Topics: Adult; Alanine; Case-Control Studies; Coronary Angiography; Cysteine; Gene Expression; Gene Frequency; Genetic Predisposition to Disease; Humans; Integrin alpha2; Male; Middle Aged; Mutation; Myocardial Infarction; Polymorphism, Genetic; Threonine | 2005 |
Association of the 1438G/A and 102T/C polymorphism of the 5-HT2A receptor gene with irritable bowel syndrome 5-HT2A gene polymorphism in irritable bowel syndrome.
Topics: Alanine; Case-Control Studies; Cysteine; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Irritable Bowel Syndrome; Polymorphism, Genetic; Receptor, Serotonin, 5-HT2A; Threonine | 2005 |
Glucose 6-phosphate release of wild-type and mutant human brain hexokinases from mitochondria.
Topics: Adenosine Triphosphate; Alanine; Animals; Binding Sites; Brain; Circular Dichroism; Dose-Response Relationship, Drug; Escherichia coli; Glucose-6-Phosphate; Hexokinase; Histidine; Humans; Kinetics; Ligands; Liver; Magnesium; Mitochondria; Models, Chemical; Mutation; N-Formylmethionine; Plasmids; Protein Binding; Protein Structure, Tertiary; Swine; Threonine | 2005 |
BAD Ser128 is not phosphorylated by c-Jun NH2-terminal kinase for promoting apoptosis.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Apoptosis; bcl-Associated Death Protein; Erythropoietin; Fibroblasts; HeLa Cells; Humans; Interleukin-3; JNK Mitogen-Activated Protein Kinases; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Serine; Species Specificity; Threonine; Transfection | 2005 |
A non-conservative, coding single-nucleotide polymorphism in the N-terminal region of lactoferrin is associated with aggressive periodontitis in an African-American, but not a Caucasian population.
Topics: Alanine; Amino Acid Substitution; Black or African American; Case-Control Studies; Conserved Sequence; Female; Humans; Lactoferrin; Male; Periodontitis; Point Mutation; Polymorphism, Single Nucleotide; Threonine; White People | 2005 |
Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms. Physiological context sets the specificity.
Topics: Adenosine Triphosphate; Alanine; Allosteric Site; Arabidopsis; Aspartate Kinase; Aspartic Acid; Chloroplasts; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Gene Expression Regulation, Plant; Genes, Reporter; Genome, Plant; Homoserine Dehydrogenase; Isoleucine; Kinetics; Methionine; Models, Biological; Plasmids; Protein Isoforms; Recombinant Proteins; Spectrophotometry; Temperature; Threonine | 2005 |
Cryoreduction EPR and 13C, 19F ENDOR study of substrate-bound substates and solvent kinetic isotope effects in the catalytic cycle of cytochrome P450cam and its T252A mutant.
Topics: Alanine; Camphor 5-Monooxygenase; Carbon Isotopes; Catalysis; Electron Spin Resonance Spectroscopy; Fluorine; Heme; Iron; Kinetics; Models, Molecular; Mutant Proteins; Mutation; Oxidation-Reduction; Oxygen; Protein Binding; Protein Structure, Tertiary; Solvents; Substrate Specificity; Threonine | 2005 |
Differential contribution of troponin I phosphorylation sites to the endothelin-modulated contractile response.
Topics: Actin Cytoskeleton; Adenoviridae; Alanine; Amiloride; Animals; Binding Sites; Calcium; Cells, Cultured; Cluster Analysis; Cyclic AMP-Dependent Protein Kinases; DNA, Complementary; Endothelins; Hydrogen-Ion Concentration; Models, Statistical; Muscle Cells; Mutagenesis; Myocardial Contraction; Myocardium; Phosphorylation; Protein Kinase C; Rats; Sarcomeres; Serine; Threonine; Time Factors; Troponin I | 2005 |
Purification and characterization of spiralin, the main protein of the Spiroplasma citri membrane.
Topics: Alanine; Bacterial Outer Membrane Proteins; Biochemistry; Buffers; Cell Membrane; Detergents; Electrophoresis; Electrophoresis, Agar Gel; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glycine; Histidine; Immunoelectrophoresis; Intracellular Membranes; Leucine; Methionine; Molecular Weight; Phenylalanine; Sepharose; Spiroplasma citri; Subcellular Fractions; Threonine; Tryptophan; Tyrosine; Valine | 1977 |
Construction, expression, and purification of HIV-TAT-survivin (T34A) mutant: a pro-apoptosis protein in Escherichia coli.
Topics: Alanine; Apoptosis; Apoptosis Regulatory Proteins; Base Sequence; Cell Line, Tumor; Escherichia coli; Gene Products, tat; HIV; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Molecular Sequence Data; Neoplasm Proteins; Point Mutation; Protein Renaturation; Recombinant Fusion Proteins; Survivin; tat Gene Products, Human Immunodeficiency Virus; Threonine | 2006 |
Posttranslational conversion of L-serines to D-alanines is vital for optimal production and activity of the lantibiotic lacticin 3147.
Topics: Alanine; Amino Acid Sequence; Bacteriocins; Chromatography, High Pressure Liquid; Codon; Glycine; Lactococcus lactis; Molecular Sequence Data; Protein Processing, Post-Translational; Serine; Structure-Activity Relationship; Threonine; Valine | 2005 |
A mutation in Wolfram syndrome type 1 gene in a Japanese family with autosomal dominant low-frequency sensorineural hearing loss.
Topics: Adolescent; Adult; Alanine; Amino Acid Substitution; Auditory Threshold; Child; Codon; Deafness; DNA Mutational Analysis; Exons; Female; Genes, Dominant; Genetic Carrier Screening; Hearing Loss, Sensorineural; Hearing Tests; Humans; Male; Membrane Proteins; Pedigree; Phenotype; Threonine; Wolfram Syndrome | 2005 |
Genetics. Zebrafish researchers hook gene for human skin color.
Topics: Alanine; Alleles; Animals; Antiporters; Asian People; Black or African American; Black People; Genes; Genetic Variation; Humans; Mutation; Selection, Genetic; Skin Pigmentation; Threonine; White People; Zebrafish; Zebrafish Proteins | 2005 |
SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans.
Topics: Alanine; Alleles; Amino Acid Sequence; Animals; Antiporters; Asian People; Biological Evolution; Black or African American; Black People; Calcium; Gene Frequency; Genes; Genetic Variation; Haplotypes; Heterozygote; Humans; Ion Transport; Melanins; Melanosomes; Mice; Molecular Sequence Data; Multifactorial Inheritance; Mutation; Pigment Epithelium of Eye; Polymorphism, Single Nucleotide; Selection, Genetic; Skin Pigmentation; Threonine; White People; Zebrafish; Zebrafish Proteins | 2005 |
The Ala45Thr polymorphism of NEUROD1 is associated with type 1 diabetes in Brazilian women.
Topics: Alanine; Amino Acid Substitution; Basic Helix-Loop-Helix Transcription Factors; Brazil; Confidence Intervals; Diabetes Mellitus, Type 1; Female; Gene Frequency; Helix-Loop-Helix Motifs; Humans; Male; Odds Ratio; Polymorphism, Single Nucleotide; Reference Values; Sex Characteristics; Threonine | 2005 |
Active site residues governing substrate selectivity and polyketide chain length in aloesone synthase.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Acyltransferases; Alanine; Amino Acid Sequence; Binding Sites; Kinetics; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Polyketide Synthases; Rheum; Sequence Alignment; Sequence Homology; Substrate Specificity; Threonine | 2006 |
CDKN2A common variant and multi-organ cancer risk--a population-based study.
Topics: Adult; Aged; Alanine; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Female; Genes, p16; Genetic Variation; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms; Odds Ratio; Poland; Prevalence; Risk Assessment; Risk Factors; Threonine | 2006 |
Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.
Topics: Alanine; alpha-Synuclein; Animals; Brain Stem; Cell Death; DNA Damage; Humans; Mice; Mice, Transgenic; Mitochondria; Mutation; Neocortex; Nerve Degeneration; Parkinson Disease; Threonine | 2006 |
Phosphorylation and transactivation of Pax6 by homeodomain-interacting protein kinase 2.
Topics: Alanine; Animals; Binding Sites; Carrier Proteins; Cell Line; Cell Line, Tumor; DNA Mutational Analysis; Eye Proteins; Glucagon; Glutamic Acid; Green Fluorescent Proteins; Homeodomain Proteins; Humans; Immunohistochemistry; Luciferases; Mass Spectrometry; Mice; Mutagenesis, Site-Directed; Mutation; p300-CBP Transcription Factors; Paired Box Transcription Factors; PAX6 Transcription Factor; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Transcription, Genetic; Transcriptional Activation; Transfection | 2006 |
Phosphorylation of serine 526 is required for MEKK3 activity, and association with 14-3-3 blocks dephosphorylation.
Topics: 14-3-3 Proteins; Alanine; Amino Acid Sequence; Catalysis; Cell Line; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Isoenzymes; MAP Kinase Kinase 6; MAP Kinase Kinase Kinase 3; Molecular Sequence Data; Mutagenesis, Site-Directed; NF-kappa B; Osmotic Pressure; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Serine; Signal Transduction; Threonine | 2006 |
Mutation of Thr466 in SHP2 abolishes its phosphatase activity, but provides a new substrate-trapping mutant.
Topics: Alanine; Amino Acid Motifs; Animals; Binding Sites; Chlorocebus aethiops; Consensus Sequence; COS Cells; Cysteine; Intracellular Signaling Peptides and Proteins; Mice; Mutation; NIH 3T3 Cells; Protein Phosphatase 2; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Substrate Specificity; Threonine; Vanadates | 2006 |
Is there a folate-related gene-environment interaction in the etiology of childhood acute lymphoblastic leukemia?
Topics: Alanine; Bone Marrow; Child; Child, Preschool; Cysteine; Dietary Supplements; DNA, Neoplasm; Female; Folic Acid; Genotype; Humans; Infant; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Odds Ratio; Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy; Threonine | 2006 |
Renin-angiotensin system gene polymorphisms: association with susceptibility to Henoch-Schonlein purpura and renal involvement.
Topics: Adolescent; Alanine; Angiotensinogen; Child; Child, Preschool; Cysteine; DNA Transposable Elements; Female; Gene Deletion; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; IgA Vasculitis; Kidney Diseases; Male; Methionine; Nephrotic Syndrome; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Proteinuria; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Severity of Illness Index; Threonine | 2006 |
Solvation of the folding-transition state in Pseudomonas aeruginosa azurin is modulated by metal: Solvation of azurin's folding nucleus.
Topics: Alanine; Azurin; Cell Nucleus; Guanidine; Metals; Point Mutation; Protein Conformation; Protein Engineering; Protein Folding; Pseudomonas aeruginosa; Solvents; Threonine; Valine; Water; Zinc | 2006 |
Cocaine self-administration in mice is inversely related to phosphorylation at Thr34 (protein kinase A site) and Ser130 (kinase CK1 site) of DARPP-32.
Topics: Alanine; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Corpus Striatum; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microdialysis; Phosphorylation; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Serine; Threonine; Time Factors | 2006 |
Differential effects of alphaCaMKII mutation on hippocampal learning and changes in intrinsic neuronal excitability.
Topics: Action Potentials; Alanine; Analysis of Variance; Animals; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Electric Stimulation; Hippocampus; In Vitro Techniques; Learning; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurons; Protein Serine-Threonine Kinases; Threonine | 2006 |
[Interactions between the MTHFR C677T and MTHFR A1298C mutations in ischaemic stroke].
Topics: Adult; Aged; Alanine; Alleles; Brain Ischemia; Cysteine; Female; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Risk Assessment; Risk Factors; Sequence Analysis, DNA; Stroke; Threonine | 2006 |
Determinants that control the specific interactions between TAB1 and p38alpha.
Topics: Adaptor Proteins, Signal Transducing; Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; beta-Galactosidase; Binding Sites; Blotting, Western; Cell Culture Techniques; Cell Line; Circular Dichroism; DNA Mutational Analysis; Enzyme Activation; Escherichia coli; Gene Deletion; Genes, Reporter; Humans; Luciferases; Mass Spectrometry; Mitogen-Activated Protein Kinase 14; Models, Molecular; Molecular Sequence Data; Point Mutation; Precipitin Tests; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Spectrum Analysis; Threonine; Transfection | 2006 |
A case of biopsy-proven leptomeningeal amyloidosis and intravenous Ig-responsive polyneuropathy associated with the Ala25Thr transthyretin gene mutation.
Topics: Alanine; Amino Acid Substitution; Amyloid Neuropathies; Amyloidosis; Brain; Brain Stem; Cerebellum; Humans; Immunoglobulins, Intravenous; Male; Meninges; Middle Aged; Point Mutation; Prealbumin; Threonine | 2006 |
Role of APP phosphorylation in FE65-dependent gene transactivation mediated by AICD.
Topics: Active Transport, Cell Nucleus; Alanine; Amyloid beta-Protein Precursor; Animals; Brain; Cell Membrane; Cells, Cultured; Mice; Mice, Inbred C57BL; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Peptide Fragments; Phosphorylation; Protein Structure, Tertiary; Threonine; Transcriptional Activation | 2006 |
Phosphorylation of the norepinephrine transporter at threonine 258 and serine 259 is linked to protein kinase C-mediated transporter internalization.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Cells, Cultured; Down-Regulation; Enzyme Activation; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Phosphorylation; Protein Kinase C; Rats; Serine; Threonine | 2006 |
Phosphorylation and 14-3-3 binding of Arabidopsis trehalose-phosphate synthase 5 in response to 2-deoxyglucose.
Topics: 14-3-3 Proteins; Alanine; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Arabidopsis; Arabidopsis Proteins; Binding Sites; Cells, Cultured; Chromatography, Affinity; Deoxyglucose; Glucosyltransferases; Humans; Immunoprecipitation; Multienzyme Complexes; Mutation, Missense; Phenformin; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Serine; Threonine | 2006 |
Ala45Thr variation in neuroD1 gene is associated with early-onset type 2 diabetes with or without diabetic pedigree in Chinese.
Topics: Adult; Aged; Alanine; Amino Acid Substitution; Basic Helix-Loop-Helix Transcription Factors; Case-Control Studies; China; Diabetes Mellitus, Type 2; Gene Frequency; Genetic Predisposition to Disease; Humans; Middle Aged; Pedigree; Polymorphism, Genetic; Threonine | 2006 |
Simultaneous substitution of Gly96 to Ala and Ala183 to Thr in 5-enolpyruvylshikimate-3-phosphate synthase gene of E. coli (k12) and transformation of rapeseed (Brassica napus L.) in order to make tolerance to glyphosate.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alanine; Amino Acid Substitution; Blotting, Southern; Brassica rapa; DNA, Plant; Escherichia coli Proteins; Glycine; Glyphosate; Herbicide Resistance; Herbicides; Mutagenesis, Site-Directed; Plants, Genetically Modified; Polymerase Chain Reaction; Threonine; Transformation, Genetic | 2007 |
Associations of a novel IL4RA polymorphism, Ala57Thr, in Greenlander Inuit.
Topics: Adult; Alanine; Alleles; Amino Acid Substitution; Denmark; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Greenland; Haplotypes; Humans; Hypersensitivity, Immediate; Interleukin-4 Receptor alpha Subunit; Inuit; Male; Polymorphism, Single Nucleotide; Receptors, Interleukin-4; Rhinitis, Allergic, Seasonal; Threonine | 2006 |
DsdX is the second D-serine transporter in uropathogenic Escherichia coli clinical isolate CFT073.
Topics: Alanine; Amino Acid Transport Systems; Biological Transport; Culture Media; Cycloserine; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Glycine; Kinetics; Membrane Transport Proteins; Models, Biological; Serine; Threonine | 2006 |
The role of a conserved serine residue within hydrogen bonding distance of FAD in redox properties and the modulation of catalysis by Ca2+/calmodulin of constitutive nitric-oxide synthases.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Calcium; Calmodulin; Catalysis; Electron Transport; Flavin-Adenine Dinucleotide; Humans; Hydrogen Bonding; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Oxidation-Reduction; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Serine; Threonine | 2006 |
The alanine/threonine polymorphism of the alpha-1-antichymotrypsin (SERPINA3) gene and ruptured intracranial aneurysms in the Japanese population.
Topics: Alanine; Aneurysm, Ruptured; Asian People; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Intracranial Aneurysm; Japan; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Serpins; Subarachnoid Hemorrhage; Threonine | 2007 |
The P1812A and P25T BRCA1 and the 5164del4 BRCA2 mutations: occurrence in high-risk non-Ashkenazi Jews.
Topics: Adult; Aged; Alanine; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; BRCA1 Protein; BRCA2 Protein; Female; Genetic Predisposition to Disease; Humans; Jews; Male; Middle Aged; Molecular Sequence Data; Pedigree; Proline; Sequence Deletion; Threonine | 2006 |
Mechanism of intracellular block of the KcsA K+ channel by tetrabutylammonium: insights from X-ray crystallography, electrophysiology and replica-exchange molecular dynamics simulations.
Topics: Alanine; Computer Simulation; Crystallography, X-Ray; Electrophysiology; Ion Channel Gating; Membranes, Artificial; Models, Molecular; Mutation; Potassium Channel Blockers; Potassium Channels; Protein Structure, Secondary; Quaternary Ammonium Compounds; Rubidium; Threonine | 2007 |
Ala394Thr polymorphism in the clock gene NPAS2: a circadian modifier for the risk of non-Hodgkin's lymphoma.
Topics: Aged; Alanine; Amino Acid Substitution; Basic Helix-Loop-Helix Transcription Factors; Circadian Rhythm; CLOCK Proteins; Connecticut; Female; Genetic Predisposition to Disease; Genetic Testing; Humans; Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Middle Aged; Molecular Epidemiology; Nerve Tissue Proteins; Polymorphism, Genetic; Population; Risk; Threonine; Trans-Activators | 2007 |
Multilocus analyses of Renin-Angiotensin-aldosterone system gene variants on blood pressure at rest and during behavioral stress in young normotensive subjects.
Topics: Adolescent; Adult; Alanine; Aldosterone; Angiotensinogen; Black People; Blood Pressure; Child; Chromosome Mapping; Female; Gene Frequency; Genetic Variation; Glycine; Humans; Male; Methionine; Peptidyl-Dipeptidase A; Phenotype; Polymorphism, Single Nucleotide; Reference Values; Renin-Angiotensin System; Rest; Stress, Psychological; Systole; Threonine; White People | 2007 |
Enhanced sampling of peptide and protein conformations using replica exchange simulations with a peptide backbone biasing-potential.
Topics: Alanine; Computer Simulation; Dipeptides; Image Enhancement; Models, Molecular; Molecular Conformation; Oligopeptides; Peptides; Protein Conformation; Proteins; Threonine | 2007 |
Distinct clinical and pathological features are associated with the BRAF(T1799A(V600E)) mutation in primary melanoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Child; Female; Gene Frequency; Glutamic Acid; Humans; Male; Melanoma; Middle Aged; Multivariate Analysis; Mutation; Pigmentation; Proto-Oncogene Proteins B-raf; Skin Neoplasms; Threonine; Valine | 2007 |
Genetic variation in thrombin-activatable fibrinolysis inhibitor (TAFI) is associated with the risk of splanchnic vein thrombosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Budd-Chiari Syndrome; Carboxypeptidase B2; Case-Control Studies; Female; Genetic Predisposition to Disease; Genetic Variation; Haplotypes; Humans; Male; Middle Aged; Netherlands; Odds Ratio; Polymorphism, Single Nucleotide; Portal Vein; Risk Factors; Threonine; Venous Thrombosis | 2007 |
FABP2 Ala54Thr polymorphism and diabetes in Chilean elders.
Topics: Aged; Alanine; Amino Acid Substitution; Chile; Cross-Sectional Studies; Diabetes Mellitus, Type 2; DNA; Fatty Acid-Binding Proteins; Female; Gene Frequency; Genotype; Humans; Insulin Resistance; Leukocytes; Male; Threonine | 2007 |
Cold exposure and associated metabolic changes in adult tropical beetles exposed to fluctuating thermal regimes.
Topics: Acclimatization; Alanine; Amino Acids; Amino Acids, Essential; Animals; Arginine; Body Temperature; Cold Temperature; Glucose; Glutamic Acid; Glutamine; Glycerol; Inositol; Lysine; Proline; Ribitol; Sorbitol; Survival Analysis; Temperature; Tenebrio; Threonine; Trehalose; Tropical Climate; Valine | 2007 |
Xanthurenic aciduria due to a mutation in KYNU encoding kynureninase.
Topics: Adenine; Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acid Substitution; Child; DNA Mutational Analysis; Genotype; Guanine; Homozygote; Humans; Hydrolases; Male; Mutation; Pedigree; Threonine; Xanthurenates | 2007 |
The CDKN2a common variants: 148 Ala/Thr and 500 C/G in 3' UTR, and their association with clinical course of melanoma.
Topics: 3' Untranslated Regions; Adult; Aged; Alanine; Amino Acid Substitution; Cyclin-Dependent Kinase Inhibitor p16; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genetic Variation; Humans; Male; Melanoma; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Polymorphism, Single-Stranded Conformational; Skin Neoplasms; Survival Analysis; Survivors; Threonine | 2007 |
Type 2 deiodinase Thr92Ala polymorphism is not associated with arterial hypertension in type 2 diabetes mellitus patients.
Topics: Alanine; Diabetes Mellitus, Type 2; Female; Genotype; Humans; Hypertension; Insulin Resistance; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Male; Middle Aged; Polymorphism, Single Nucleotide; Reproducibility of Results; Risk Factors; Threonine | 2007 |
Major Cdk5-dependent phosphorylation sites of amphiphysin 1 are implicated in the regulation of the membrane binding and endocytosis.
Topics: Alanine; Animals; Cyclin-Dependent Kinase 5; Drug Interactions; Endocytosis; Humans; Lipids; Liposomes; Mass Spectrometry; Microscopy, Electron, Scanning; Mutagenesis; Nerve Tissue Proteins; PC12 Cells; Phosphorylation; Protein Kinase Inhibitors; Purines; Rats; Roscovitine; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Transfection | 2007 |
Structural modelling and mutation analysis of a nociceptin receptor and its ligand complexes.
Topics: Alanine; DNA Mutational Analysis; Humans; Hydrogen Bonding; Imaging, Three-Dimensional; Ligands; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Mutation; Nociceptin; Nociceptin Receptor; Opioid Peptides; Receptors, G-Protein-Coupled; Receptors, Opioid; Software; Threonine | 2007 |
Behavioral phenotypes of Disc1 missense mutations in mice.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Alanine; Animals; Behavior, Animal; Brain; Cyclic Nucleotide Phosphodiesterases, Type 4; DNA Mutational Analysis; Female; Glutamine; Humans; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation, Missense; Nerve Tissue Proteins; Neural Inhibition; Phenotype; Protein Binding; Reflex, Acoustic; Subcellular Fractions; Threonine | 2007 |
Analyses of GDF9 mutation in 100 Chinese women with premature ovarian failure.
Topics: Adult; Alanine; Amino Acid Substitution; Asian People; Bone Morphogenetic Protein 15; DNA Mutational Analysis; Female; Growth Differentiation Factor 9; Humans; Intercellular Signaling Peptides and Proteins; Mutation; Polymorphism, Single Nucleotide; Primary Ovarian Insufficiency; Threonine | 2007 |
The Ala53Thr mutation in the alpha-synuclein gene in a Korean family with Parkinson disease.
Topics: Adult; Age of Onset; Alanine; alpha-Synuclein; Amino Acid Substitution; Family; Haplotypes; Humans; Korea; Male; Mutation; Parkinson Disease; Pedigree; Threonine | 2007 |
Synthesis of bisaminoacylated pdCpAs and tandemly activated transfer RNAs.
Topics: Acetylation; Alanine; Amino Acids; Bacterial Proteins; Homoserine; Indicators and Reagents; Methionine; Protein Biosynthesis; RNA, Transfer; Tetrahydrofolate Dehydrogenase; Thermus thermophilus; Threonine | 2007 |
Antifreeze proteins at the ice/water interface: three calculated discriminating properties for orientation of type I proteins.
Topics: Alanine; Algorithms; Antifreeze Proteins; Asparagine; Binding Sites; Biophysics; Computer Simulation; Hydrogen Bonding; Ice; Molecular Conformation; Oxygen; Proteins; Thermodynamics; Threonine; Water | 2007 |
A mutation on influenza C virus M1 protein affects virion morphology by altering the membrane affinity of the protein.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cell Membrane; Cloning, Molecular; Gammainfluenzavirus; Humans; Molecular Sequence Data; Mutation; RNA, Viral; Threonine; Viral Matrix Proteins; Virion | 2007 |
OCA2 481Thr, a hypofunctional allele in pigmentation, is characteristic of northeastern Asian populations.
Topics: Alanine; Alleles; Asian People; Gene Frequency; Genotype; Humans; Membrane Transport Proteins; Population; Skin Pigmentation; Threonine; Ultraviolet Rays | 2007 |
Early onset progressive ataxia associated with the first CACNA1A mutation identified within the I-II loop.
Topics: Alanine; Ataxia; Calcium Channels; Disease Progression; Humans; Mutation; Protein Structure, Tertiary; Threonine | 2007 |
Polymorphism of the FABP2 gene: a population frequency analysis and an association study with cardiovascular risk markers in Argentina.
Topics: Adult; Aged; Alanine; Argentina; Biomarkers; Cardiovascular Diseases; Fatty Acid-Binding Proteins; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Risk Factors; Threonine | 2007 |
Purine nucleoside phosphorylase deficiency in a patient with spastic paraplegia and recurrent infections.
Topics: Alanine; Antigens, CD; Child, Preschool; DNA Mutational Analysis; Exons; Female; Humans; Lymphocytes; Mutation; Paraplegia; Purine-Nucleoside Phosphorylase; Threonine | 2007 |
Stereoselective syntheses of 4-oxa diaminopimelic acid and its protected derivatives via aziridine ring opening.
Topics: Alanine; Amino Acids; Aziridines; Catalysis; Diaminopimelic Acid; Haemophilus influenzae; Molecular Structure; Racemases and Epimerases; Serine; Stereoisomerism; Sulfides; Threonine | 2007 |
Asp125 and Thr130 in transmembrane domain 3 are major sites of alpha1b-adrenergic receptor antagonist binding.
Topics: Adrenergic alpha-Antagonists; Alanine; Aspartic Acid; Binding, Competitive; Blotting, Western; Cells, Cultured; DNA, Complementary; Humans; Hydrolysis; Ligands; Models, Molecular; Phosphatidylinositols; Prazosin; Receptors, Adrenergic, alpha-1; Threonine; Transfection | 2007 |
Haemostatic genetic variants, ABO blood group and bleeding risk during oral anticoagulant treatment after cerebral ischaemia of arterial origin.
Topics: ABO Blood-Group System; Administration, Oral; Aged; Alanine; Anticoagulants; Arteries; Blood Proteins; Brain Ischemia; Case-Control Studies; Confidence Intervals; Female; Fibrinogen; Genetic Variation; Hemorrhage; Humans; International Normalized Ratio; Male; Middle Aged; Odds Ratio; Risk Factors; Threonine | 2007 |
The role of the conserved threonine in P450 BM3 oxygen activation: substrate-determined hydroxylation activity of the Thr268Ala mutant.
Topics: Alanine; Amino Acid Sequence; Bacillus megaterium; Binding Sites; Catalysis; Cytochrome P-450 Enzyme System; Fatty Acids; Heme; Hydroxylation; Kinetics; Mixed Function Oxygenases; Molecular Sequence Data; Mutation; Oxidation-Reduction; Oxygen; Substrate Specificity; Threonine | 2008 |
Atypical early-onset Alzheimer's disease caused by the Iranian APP mutation.
Topics: Alanine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Blood Pressure; DNA Mutational Analysis; Electroencephalography; Family Health; Humans; Iran; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Peptide Fragments; Threonine | 2008 |
Functional and structural roles of conserved cysteine residues in the carboxyl-terminal domain of the follicle-stimulating hormone receptor in human embryonic kidney 293 cells.
Topics: Alanine; Amino Acid Sequence; Cell Line; Computer Simulation; Cyclic AMP; Cysteine; Humans; Kidney; Lipoylation; Molecular Sequence Data; Mutation; Receptors, FSH; Serine; Threonine | 2008 |
TDP-43 A315T mutation in familial motor neuron disease.
Topics: Aged; Aged, 80 and over; Alanine; Amino Acid Sequence; Amino Acid Substitution; DNA Mutational Analysis; DNA-Binding Proteins; Female; Genes, Dominant; Humans; Male; Middle Aged; Molecular Sequence Data; Motor Neuron Disease; Mutation, Missense; Pedigree; Threonine | 2008 |
Congenital hypersensitivity to vitamin K antagonists due to FIX propeptide mutation at locus -10: a (not so) rare cause of bleeding under oral anticoagulant therapy in Switzerland.
Topics: Aged; Alanine; Amino Acid Substitution; Anticoagulants; Coumarins; Drug Hypersensitivity; Factor IX; Heart Valve Prosthesis Implantation; Hemorrhage; Heterozygote; Humans; International Normalized Ratio; Male; Mutation; Partial Thromboplastin Time; Pedigree; Protein Precursors; Switzerland; Threonine; Vitamin K | 2008 |
The antiviral drug selected hepatitis B virus rtA181T/sW172* mutant has a dominant negative secretion defect and alters the typical profile of viral rebound.
Topics: Alanine; Amino Acid Sequence; Antiviral Agents; Cell Line, Tumor; Codon, Terminator; DNA Replication; Genes, Dominant; Glycosylation; Hepatitis B virus; Humans; Membrane Proteins; Microscopy, Electron; Mutation; RNA-Directed DNA Polymerase; Threonine; Tissue Distribution; Transfection; Viral Load; Virion; Virus Replication | 2008 |
Alpha-Ca2+/calmodulin-dependent protein kinase II contributes to the developmental programming of anxiety in serotonin receptor 1A knock-out mice.
Topics: Actins; Alanine; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disks Large Homolog 4 Protein; Exploratory Behavior; Guanylate Kinases; Hippocampus; Hypothermia, Induced; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Phosphorylation; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1A; Serotonin Antagonists; Synaptosomes; Threonine | 2008 |
Disruption of agonist and ligand activity in an AMPA glutamate receptor splice-variable domain deletion mutant.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Larva; Leucine; Ligands; Membrane Potentials; Microinjections; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Receptors, AMPA; Sequence Deletion; Threonine; Xenopus | 2008 |
Two novel alleles of tottering with distinct Ca(v)2.1 calcium channel neuropathologies.
Topics: Alanine; Animals; Animals, Newborn; Calbindins; Calcium Channels, N-Type; Cells, Cultured; Cysteine; Disease Models, Animal; Glycine; Green Fluorescent Proteins; Ion Channel Gating; Membrane Potentials; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; Models, Molecular; Mutation; Nervous System Diseases; Patch-Clamp Techniques; Purkinje Cells; S100 Calcium Binding Protein G; Silver Staining; Threonine; Tyrosine 3-Monooxygenase | 2008 |
Core level study of alanine and threonine.
Topics: Absorption; Alanine; Electrons; Hydroxyl Radical; Molecular Conformation; Photons; Sensitivity and Specificity; Spectrum Analysis; Threonine; Volatilization | 2008 |
Phosphorylation of MyoGEF on Thr-574 by Plk1 promotes MyoGEF localization to the central spindle.
Topics: Alanine; Cell Cycle; Cell Cycle Proteins; Cytokinesis; Guanine Nucleotide Exchange Factors; HeLa Cells; Humans; Microscopy, Fluorescence; Mitosis; Models, Biological; Phosphorylation; Plasmids; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA; Spindle Apparatus; Threonine | 2008 |
FMRFamide neuropeptides and acetylcholine synergistically inhibit egg-laying by C. elegans.
Topics: Acetylcholine; Alanine; Animals; Animals, Genetically Modified; Behavior, Animal; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Female; FMRFamide; Gene Expression Regulation; Green Fluorescent Proteins; Membrane Potentials; Membrane Transport Modulators; Motor Neurons; Mutation; Neural Inhibition; Patch-Clamp Techniques; Peptides; Receptors, G-Protein-Coupled; Reproduction; Signal Transduction; Threonine | 2008 |
Novel mutations in the IRF6 gene in Brazilian families with Van der Woude syndrome.
Topics: Alanine; American Indian or Alaska Native; Amino Acid Sequence; Base Sequence; Brazil; Craniofacial Abnormalities; DNA Mutational Analysis; Electrophoresis, Agar Gel; Family; Humans; Interferon Regulatory Factors; Molecular Sequence Data; Mutation; Restriction Mapping; Syndrome; Threonine | 2008 |
Efficient inhibition of murine breast cancer growth and metastasis by gene transferred mouse survivin Thr34-->Ala mutant.
Topics: Alanine; Amino Acid Substitution; Animals; Fatty Acids, Monounsaturated; Female; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Inhibitor of Apoptosis Proteins; Liposomes; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Microtubule-Associated Proteins; Neoplasm Metastasis; Quaternary Ammonium Compounds; Repressor Proteins; Survivin; Threonine | 2008 |
Effect of endothelium-specific insulin resistance on endothelial function in vivo.
Topics: Alanine; Amino Acid Substitution; Animals; beta-Galactosidase; Blood Glucose; Cloning, Molecular; Endothelium, Vascular; Glucose Tolerance Test; Homeostasis; Humans; Insulin Resistance; Mice; Mice, Transgenic; Mutagenesis, Site-Directed; Mutation; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Plasmids; Polymerase Chain Reaction; Receptor, Insulin; Reverse Transcriptase Polymerase Chain Reaction; Threonine | 2008 |
Specific JNK inhibition by D-JNKI1 protects Purkinje cells from cell death in Lurcher mutant mouse.
Topics: Alanine; Amino Acid Substitution; Animals; Animals, Newborn; Cell Death; Cell Membrane Permeability; Cerebellum; Crosses, Genetic; Female; Genotype; Male; MAP Kinase Kinase 4; Mice; Mice, Neurologic Mutants; Mutation; Neurons; Peptides; Purkinje Cells; Receptors, Glutamate; Threonine | 2008 |
Phosphorylation of CAP-G is required for its chromosomal DNA localization during mitosis.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Animals; CDC2 Protein Kinase; Cell Cycle Proteins; Chromosomes, Human; Cyclin B; DNA; DNA-Binding Proteins; HeLa Cells; Humans; Mitosis; Molecular Sequence Data; Multiprotein Complexes; Mutation; Phosphorylation; Threonine; Xenopus | 2008 |
Epidermodysplasia verruciformis in a HIV-positive patient homozygous for the c917A-->T polymorphism in the TMC8/EVER2 gene.
Topics: Adult; AIDS-Related Opportunistic Infections; Alanine; Epidermodysplasia Verruciformis; Female; HIV Infections; Homozygote; Humans; Immunocompromised Host; Membrane Proteins; Mutation; Papillomaviridae; Polymorphism, Single Nucleotide; Threonine | 2009 |
Novel ATP13A2 variant associated with Parkinson disease in Taiwan and Singapore.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Asian People; DNA Mutational Analysis; Exons; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Middle Aged; Models, Molecular; Mutation; Parkinson Disease; Positron-Emission Tomography; Proton-Translocating ATPases; Singapore; Taiwan; Threonine; Young Adult | 2008 |
Mitochondrial tRNALeu/Lys and ATPase 6/8 gene variations in spinocerebellar ataxias.
Topics: Alanine; Amino Acid Substitution; Ataxin-3; Ataxin-7; Ataxins; Calcium Channels; DNA; DNA Primers; Gene Amplification; Genetic Variation; Glycine; Humans; Methionine; Mitochondrial Proton-Translocating ATPases; Nerve Tissue Proteins; Nuclear Proteins; Repressor Proteins; RNA, Transfer, Leu; RNA, Transfer, Lys; Spinocerebellar Ataxias; Threonine; Trinucleotide Repeats; Valine | 2009 |
A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward-facing conformation.
Topics: Alanine; Amino Acid Motifs; Amino Acid Substitution; Amphetamine; Cell Line; Cell Membrane; Computer Simulation; Conserved Sequence; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Humans; Models, Molecular; Mutation; Protein Conformation; Thermodynamics; Threonine | 2009 |
D-serine induces lipid and protein oxidative damage and decreases glutathione levels in brain cortex of rats.
Topics: Alanine; Analysis of Variance; Animals; Antioxidants; Cerebral Cortex; Glutathione; Lipid Peroxidation; Luminescence; Oxidants; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Serine; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances; Threonine | 2009 |
Selective noradrenergic vulnerability in α-synuclein transgenic mice.
Topics: Alanine; alpha-Synuclein; Animals; Disease Models, Animal; Humans; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Norepinephrine; Parkinson Disease; Threonine | 2010 |
Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux.
Topics: Adenosine Triphosphate; Alanine; alpha-Synuclein; Analysis of Variance; Animals; Calcium; Cell Line, Tumor; Cobalt; Dose-Response Relationship, Drug; Flufenamic Acid; Gene Expression Regulation; Green Fluorescent Proteins; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Mitochondria; Mutation; Neuroblastoma; Neurons; Protein Kinases; Rats; Threonine; Transfection; Tryptophan | 2009 |
Homology modeling of human alpha 1 beta 2 gamma 2 and house fly beta 3 GABA receptor channels and Surflex-docking of fipronil.
Topics: Alanine; Amino Acid Sequence; Animals; Cryoelectron Microscopy; GABA-A Receptor Antagonists; Houseflies; Humans; Insecticides; Models, Molecular; Molecular Sequence Data; Protein Conformation; Pyrazoles; Receptors, GABA-A; Receptors, Nicotinic; Threonine; Torpedo | 2009 |
CASK point mutation regulates protein-protein interactions and NR2b promoter activity.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Brain; Gene Expression Regulation; Guanylate Kinases; Mice; Molecular Sequence Data; Nerve Tissue Proteins; Point Mutation; Promoter Regions, Genetic; Rats; Receptors, N-Methyl-D-Aspartate; T-Box Domain Proteins; Threonine | 2009 |
Identification of serine/threonine kinase substrates in the human pathogen group B streptococcus.
Topics: Alanine; Bacterial Proteins; Binding Sites; Chromatography, Liquid; Humans; Mutagenesis, Site-Directed; Mutation; Phosphopeptides; Phosphorylation; Protein Serine-Threonine Kinases; Proteomics; Reproducibility of Results; Streptococcus agalactiae; Substrate Specificity; Tandem Mass Spectrometry; Threonine | 2009 |
Release of endogenous amino acids from the hippocampus and brain stem from developing and adult mice in ischemia.
Topics: Aging; Alanine; Animals; Aspartic Acid; Brain Ischemia; Brain Stem; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Male; Mice; Potassium; Serine; Taurine; Threonine | 2009 |
The Ala54Thr polymorphism in the fatty acid-binding protein 2 gene leads to higher food intake in Japanese women.
Topics: Alanine; Eating; Fatty Acid-Binding Proteins; Female; Genotype; Humans; Japan; Polymorphism, Genetic; Surveys and Questionnaires; Threonine; Young Adult | 2009 |
Ala54Thr polymorphism of the fatty acid binding protein 2 gene and saturated fat intake in relation to lipid levels and insulin resistance: the Coronary Artery Risk Development in Young Adults (CARDIA) study.
Topics: Adult; Alanine; Amino Acid Substitution; Cohort Studies; Coronary Artery Disease; Dietary Fats; Eating; Fatty Acid-Binding Proteins; Fatty Acids; Female; Humans; Insulin Resistance; Lipid Metabolism; Male; Polymorphism, Single Nucleotide; Risk Factors; Threonine; Young Adult | 2009 |
Ala54Thr polymorphism of fatty acid binding protein 2, role on insulin resistance and cardiovascular risk factors in presurgical morbid obesity patients.
Topics: Adipokines; Adult; Alanine; Alleles; C-Reactive Protein; Cholesterol; Fatty Acid-Binding Proteins; Female; Gene Frequency; Humans; Insulin Resistance; Male; Middle Aged; Obesity, Morbid; Polymorphism, Genetic; Risk Factors; Threonine; Triglycerides | 2009 |
Conserved threonine residues within the A-loop of the receptor NIK differentially regulate the kinase function required for antiviral signaling.
Topics: Alanine; Amino Acid Sequence; Antiviral Agents; Arabidopsis; Arabidopsis Proteins; Cell Nucleus; Geminiviridae; Molecular Sequence Data; Mutation; Nicotiana; Phosphorylation; Point Mutation; Protein Structure, Tertiary; Ribosomal Protein L10; Ribosomal Proteins; Sequence Homology, Amino Acid; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Viruses | 2009 |
Enterocin C, a class IIb bacteriocin produced by E. faecalis C901, a strain isolated from human colostrum.
Topics: Alanine; Amino Acid Sequence; Anti-Infective Agents; Bacteriocin Plasmids; Bacteriocins; Base Sequence; Colostrum; Enterococcus faecalis; Female; Genes, Bacterial; Humans; Molecular Sequence Data; Peptides; Pregnancy; Threonine | 2009 |
Phosphorylation-dependent autoinhibition of myosin light chain phosphatase accounts for Ca2+ sensitization force of smooth muscle contraction.
Topics: Alanine; Calcium; Calcium Signaling; Catalytic Domain; Escin; Glutathione Transferase; Humans; Inhibitory Concentration 50; Muscle Contraction; Muscle, Smooth; Mutation; Myosin-Light-Chain Phosphatase; Phosphorylation; Protein Structure, Tertiary; Threonine | 2009 |
Cyclin D2 protein stability is regulated in pancreatic beta-cells.
Topics: Alanine; Animals; Apoptosis; Crosses, Genetic; Cyclin D2; Exenatide; Gene Expression Regulation; Insulin-Secreting Cells; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Mutation; Peptides; RNA, Messenger; Threonine; Venoms | 2009 |
Ala147Thr substitution in translocator protein is associated with adult separation anxiety in patients with depression.
Topics: Adult; Alanine; Amino Acid Substitution; Anxiety, Separation; Depression; Female; Genetic Predisposition to Disease; Humans; Male; Polymorphism, Single Nucleotide; Receptors, GABA; Threonine | 2009 |
Type 2 deiodinase Thr92Ala polymorphism impact on clinical course and myocardial remodeling in patients with Graves' disease.
Topics: Adult; Alanine; Echocardiography; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Graves Disease; Humans; Male; Polymorphism, Genetic; Threonine; Ventricular Remodeling; Young Adult | 2009 |
[Study on the relationship between FABP2 Ala54Thr polymorphism and the risk of non-alcoholic fatty liver diseases].
Topics: Adult; Aged; Alanine; Amino Acid Substitution; Case-Control Studies; Fatty Acid-Binding Proteins; Fatty Liver; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Risk Factors; Threonine; Young Adult | 2009 |
HslVU ATP-dependent protease utilizes maximally six among twelve threonine active sites during proteolysis.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Substitution; Binding Sites; Catalysis; Electrophoresis, Polyacrylamide Gel; Endopeptidase Clp; Enzyme Assays; Escherichia coli Proteins; Hydrolysis; Kinetics; Models, Biological; Mutation; Peptides; Protein Binding; Protein Subunits; Spectrometry, Fluorescence; Substrate Specificity; Threonine | 2009 |
The interferon-induced helicase IFIH1 Ala946Thr polymorphism is associated with type 1 diabetes in both the high-incidence Finnish and the medium-incidence Hungarian populations.
Topics: Age of Onset; Alanine; Amino Acid Substitution; Child; DEAD-box RNA Helicases; Diabetes Mellitus, Type 1; Europe; Finland; Genotype; Humans; Hungary; Interferon-Induced Helicase, IFIH1; Meta-Analysis as Topic; Polymorphism, Single Nucleotide; Threonine | 2010 |
AMINO ACID COMPOSITION OF HIGHLY PURIFIED VIRAL PARTICLES OF INFLUENZA A AND B.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Humans; Influenza, Human; Isoleucine; Leucine; Lysine; Methionine; Orthomyxoviridae; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine; Virion | 1947 |
Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster.
Topics: Acetylation; Alanine; Animals; Animals, Genetically Modified; Binding Sites; Blotting, Western; Carboxy-Lyases; Cell Line; Databases, Protein; Drosophila melanogaster; Drosophila Proteins; HeLa Cells; Humans; Immunoprecipitation; Mass Spectrometry; Mutation; Protein Biosynthesis; Protein Processing, Post-Translational; Serine; Threonine; Transgenes | 2009 |
Conformational effects of the non-natural alpha-methylserine on small peptides and glycopeptides.
Topics: Alanine; Amides; Amino Acid Sequence; Glycopeptides; Glycosylation; Molecular Dynamics Simulation; Molecular Sequence Data; Peptides; Protein Conformation; Serine; Solvents; Threonine; Water | 2009 |
Antitumor effect of mSurvivinThr34→Ala in murine colon carcinoma when administered intravenously.
Topics: Adoptive Transfer; Alanine; Animals; Apoptosis; Blotting, Western; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Movement; Cell Proliferation; Colonic Neoplasms; Female; Genetic Therapy; Humans; Immunoenzyme Techniques; Inhibitor of Apoptosis Proteins; Injections, Intravenous; Liposomes; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Repressor Proteins; Survivin; Threonine | 2010 |
Differential phospholipid binding of alpha-synuclein variants implicated in Parkinson's disease revealed by solution NMR spectroscopy.
Topics: Alanine; alpha-Synuclein; Genetic Variation; Glutamic Acid; Humans; Lysine; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Parkinson Disease; Peptide Fragments; Phospholipids; Proline; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Solutions; Threonine | 2010 |
Functional analysis of the missense APOC3 mutation Ala23Thr associated with human hypotriglyceridemia.
Topics: Alanine; Apolipoproteins C; Brefeldin A; Carrier Proteins; Cell Line; Gene Expression Regulation; Humans; Lipid Metabolism Disorders; Lipoproteins, IDL; Lipoproteins, LDL; Lipoproteins, VLDL; Microsomes; Models, Molecular; Mutation, Missense; Protein Binding; Protein Structure, Secondary; Threonine; Triglycerides | 2010 |
An improved procedure for the synthesis of dehydroamino acids and dehydropeptides from the carbonate derivatives of serine and threonine using tetrabutylammonium fluoride.
Topics: Alanine; Carbonates; gamma-Aminobutyric Acid; Peptides; Quaternary Ammonium Compounds; Serine; Threonine | 2010 |
Comprehensive and cost-effective NMR spectroscopy of methyl groups in large proteins.
Topics: Alanine; Escherichia coli Proteins; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Membrane Transport Proteins; Periplasmic Proteins; Reference Standards; Threonine; Valine | 2010 |
The type 2 deiodinase Thr92Ala polymorphism is associated with increased bone turnover and decreased femoral neck bone mineral density.
Topics: Alanine; Amino Acid Substitution; Bone Density; Bone Remodeling; Female; Femur Neck; Genotype; Humans; Iodide Peroxidase; Male; Middle Aged; Polymorphism, Single Nucleotide; Threonine | 2010 |
Manganese superoxide dismutase (MnSOD) gene (Ala-9Val, Ile58Thr) polymorphism in patients with age-related macular degeneration (AMD).
Topics: Aged; Alanine; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Humans; Isoleucine; Macular Degeneration; Male; Middle Aged; Models, Genetic; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Threonine; Valine | 2010 |
Two haplotypes of the P2X(7) receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1beta secretion.
Topics: Adenosine Triphosphate; Alanine; Blood Cells; Erythrocytes; Ethidium; Genotype; Haplotypes; Humans; Interleukin-1beta; Ion Transport; Monocytes; Mutation, Missense; Polymorphism, Genetic; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Threonine; Up-Regulation | 2010 |
A single-nucleotide polymorphism of alanine to threonine at position 163 of the human angiotensin II type 1 receptor impairs Losartan affinity.
Topics: Alanine; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Chlorocebus aethiops; COS Cells; Humans; Imidazoles; Inositol Phosphates; Irbesartan; Losartan; Polymorphism, Single Nucleotide; Receptor, Angiotensin, Type 1; Telmisartan; Tetrazoles; Threonine; Valine; Valsartan | 2010 |
Analysis of two polymorphisms of the manganese superoxide dismutase gene (Ile-58Thr and Ala-9Val) in patients with recurrent depressive disorder.
Topics: Alanine; Amino Acids; Case-Control Studies; Depression; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Isoleucine; Male; Middle Aged; Polymorphism, Genetic; Sex Factors; Superoxide Dismutase; Threonine; Valine | 2010 |
Amyotrophic lateral sclerosis-frontotemporal lobar dementia in 3 families with p.Ala382Thr TARDBP mutations.
Topics: Adult; Aged; Alanine; Amyotrophic Lateral Sclerosis; Brain; Cognition Disorders; DNA-Binding Proteins; Family Health; Female; Frontotemporal Lobar Degeneration; Functional Laterality; Humans; Italy; Magnetic Resonance Imaging; Male; Middle Aged; Mutation, Missense; Positron-Emission Tomography; Superoxide Dismutase; Superoxide Dismutase-1; Threonine | 2010 |
Amino acid substitutions in the FXYD motif enhance phospholemman-induced modulation of cardiac L-type calcium channels.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Calcium Channels, L-Type; Cell Line; Humans; Ion Channel Gating; Membrane Proteins; Molecular Sequence Data; Mutation; Patch-Clamp Techniques; Phosphoproteins; Threonine | 2010 |
Catalysis of lysine 48-specific ubiquitin chain assembly by residues in E2 and ubiquitin.
Topics: Alanine; Binding Sites; Catalysis; Catalytic Domain; Glutamine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Models, Molecular; Polyubiquitin; Protein Conformation; Protein Processing, Post-Translational; Saccharomyces cerevisiae Proteins; Structure-Activity Relationship; Threonine; Tyrosine; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitination | 2010 |
Polymorphism Ala54Thr of fatty acid-binding protein 2: Allelic frequencies and influence on cardiovascular risk factors in a multicenter study of Castilla y Leon.
Topics: Adult; Alanine; Anthropometry; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Cross-Sectional Studies; Fatty Acid-Binding Proteins; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Insulin Resistance; Male; Mutation; Obesity; Phenotype; Polymorphism, Genetic; Risk Factors; Spain; Threonine | 2010 |
Molecular characterization of tissue-nonspecific alkaline phosphatase with an Ala to Thr substitution at position 116 associated with dominantly inherited hypophosphatasia.
Topics: Alanine; Alkaline Phosphatase; Amino Acid Substitution; Animals; Blotting, Western; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Cricetulus; Disulfides; Gene Expression; Genes, Dominant; Humans; Hypophosphatasia; Immunoprecipitation; Mutation, Missense; Threonine | 2011 |
Multiple endocrine neoplasia type 2B with a RET proto-oncogene A883F mutation displays a more indolent form of medullary thyroid carcinoma compared with a RET M918T mutation.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Alanine; Carcinoma, Neuroendocrine; Female; Germ-Line Mutation; Humans; Methionine; Multiple Endocrine Neoplasia Type 2b; Phenylalanine; Pheochromocytoma; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Risk Factors; Threonine; Thyroid Neoplasms; Thyroidectomy; Treatment Outcome | 2011 |
Large proportion of amyotrophic lateral sclerosis cases in Sardinia due to a single founder mutation of the TARDBP gene.
Topics: Aged; Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Case-Control Studies; DNA Mutational Analysis; DNA-Binding Proteins; Female; Founder Effect; Genetic Predisposition to Disease; Genotype; Humans; Italy; Male; Middle Aged; Mutation, Missense; Phenotype; Prospective Studies; RNA-Binding Protein FUS; Superoxide Dismutase; Superoxide Dismutase-1; Threonine | 2011 |
[Analysis of the FABP2 gene Ala54Thr polymorphism in non-obese and obese Chinese].
Topics: Aged; Alanine; Asian People; Cholesterol, HDL; Fatty Acid-Binding Proteins; Female; Humans; Male; Middle Aged; Obesity; Polymorphism, Genetic; Threonine; Triglycerides | 2011 |
The Thr- and Ala-rich hyperactive antifreeze protein from inchworm folds as a flat silk-like β-helix.
Topics: Alanine; Amino Acid Sequence; Animals; Antifreeze Proteins; Base Sequence; Chromatography, Affinity; Circular Dichroism; DNA Primers; DNA, Complementary; Expressed Sequence Tags; Larva; Molecular Dynamics Simulation; Molecular Sequence Data; Moths; Polymerase Chain Reaction; Protein Folding; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2011 |
Renin-angiotensin-aldosterone system genes and nonarteritic anterior ischemic optic neuropathy.
Topics: Age Factors; Aged; Aged, 80 and over; Alanine; Alleles; Angiotensinogen; Confidence Intervals; Cysteine; DNA Transposable Elements; Female; Gene Deletion; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Odds Ratio; Optic Neuropathy, Ischemic; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sex Factors; Threonine | 2011 |
Broadening the phenotype of TARDBP mutations: the TARDBP Ala382Thr mutation and Parkinson's disease in Sardinia.
Topics: Aged; Alanine; Amino Acid Substitution; Case-Control Studies; Cohort Studies; DNA Mutational Analysis; DNA-Binding Proteins; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Italy; Male; Middle Aged; Mutation, Missense; Nerve Degeneration; Parkinson Disease; Threonine | 2011 |
A switch I mutant of Cdc42 exhibits less conformational freedom.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; cdc42 GTP-Binding Protein; Crystallography, X-Ray; Humans; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Molecular Sequence Data; Protein Binding; Protein Conformation; Protein Interaction Mapping; Signal Transduction; Threonine | 2011 |
First report of a novel extended-spectrum beta-lactamase KOXY-2 producing Klebsiella oxytoca that hydrolyses cefotaxime and ceftazidime.
Topics: Alanine; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Cefotaxime; Ceftazidime; DNA Gyrase; Humans; Hydrolysis; Klebsiella oxytoca; Mutation; Scotland; Threonine | 2011 |
Genome-enabled determination of amino acid biosynthesis in Xanthomonas campestris pv. campestris and identification of biosynthetic pathways for alanine, glycine, and isoleucine by 13C-isotopologue profiling.
Topics: Alanine; Amino Acids; Biosynthetic Pathways; Carbon Isotopes; Genetic Complementation Test; Genome, Bacterial; Glycine; Isoleucine; Magnetic Resonance Spectroscopy; Metabolic Networks and Pathways; Metabolome; Methionine; Models, Biological; Pyruvic Acid; Threonine; Xanthomonas campestris | 2011 |
Structural insight into the Mycobacterium tuberculosis Rv0020c protein and its interaction with the PknB kinase.
Topics: Alanine; Bacterial Proteins; Binding Sites; Catalytic Domain; Cloning, Molecular; Escherichia coli; Fluorescence Polarization; Magnetic Resonance Spectroscopy; Membrane Proteins; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; Phosphorylation; Plasmids; Protein Binding; Protein Folding; Protein Interaction Mapping; Protein Serine-Threonine Kinases; Recombinant Proteins; Substrate Specificity; Threonine | 2011 |
Enhancement of the inhibitory effect of an IL-15 antagonist peptide by alanine scanning.
Topics: Alanine; Amino Acid Sequence; Arthritis, Rheumatoid; Cell Line; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Humans; Inhibitory Concentration 50; Interleukin-15; Interleukin-15 Receptor alpha Subunit; Lysine; Molecular Sequence Data; Peptides; Protein Binding; Structure-Activity Relationship; Synovial Fluid; T-Lymphocytes; Threonine; Tumor Necrosis Factor-alpha | 2012 |
Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses.
Topics: Acoustic Stimulation; Age Factors; Alanine; Animals; Cells, Cultured; Cerebral Cortex; Chromatin Immunoprecipitation; Conditioning, Psychological; DNA Mutational Analysis; DNA-Binding Proteins; Electroencephalography; Embryo, Mammalian; Evoked Potentials, Auditory, Brain Stem; Exploratory Behavior; Fear; Gene Expression Regulation; Humans; Maze Learning; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Mutation; Neurons; Spectrum Analysis; Threonine | 2011 |
Are thrombophilia more multifactorial than we thought: report of mosaicism for FII G20210A and novel FII T20061C gene variants.
Topics: Alanine; Biomarkers; Cysteine; Female; Genotype; Glycine; Humans; Hypertension, Pulmonary; Middle Aged; Mosaicism; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Prothrombin; Pulmonary Embolism; Recurrence; Risk Factors; Threonine; Thrombophilia | 2012 |
[Determination of amino acid contents in cottonseeds using near infrared reflectance spectroscopy].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Calibration; Cottonseed Oil; Cystine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Spectroscopy, Near-Infrared; Threonine; Tyrosine; Valine | 2011 |
Functional characterization of MODY2 mutations highlights the importance of the fine-tuning of glucokinase and its role in glucose sensing.
Topics: Adolescent; Adult; Alanine; Amino Acid Substitution; Child; Child, Preschool; Diabetes Mellitus, Type 2; Female; Glucokinase; Glucose; Humans; Infant; Male; Mutation, Missense; Threonine; Young Adult | 2012 |
Suppressive regulation of KSHV RTA with O-GlcNAcylation.
Topics: Acylation; Alanine; Amino Acid Substitution; Blotting, Western; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation, Viral; HEK293 Cells; Herpesvirus 8, Human; Humans; Immediate-Early Proteins; Immunoprecipitation; N-Acetylglucosaminyltransferases; Oligopeptides; Peptides; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; RNA, Small Interfering; Tandem Mass Spectrometry; Threonine; Trans-Activators | 2012 |
Gly or Ala substitutions for Pro(210)Thr(211)Asn(212) at the β8-β9 turn of subtilisin Carlsberg increase the catalytic rate and decrease thermostability.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Bacillus; Bacterial Proteins; Biocatalysis; Catalytic Domain; Enzyme Stability; Glycine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Proline; Proteolysis; Sequence Homology, Amino Acid; Subtilisins; Threonine | 2012 |
Prevalence of the NKG2D Thr72Ala polymorphism in patients with cervical carcinoma.
Topics: Adult; Alanine; Base Sequence; Case-Control Studies; DNA Primers; Female; Humans; Middle Aged; NK Cell Lectin-Like Receptor Subfamily K; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Threonine; Uterine Cervical Neoplasms | 2012 |
Ring substituents on substituted benzamide ligands indirectly mediate interactions with position 7.39 of transmembrane helix 7 of the D4 dopamine receptor.
Topics: Alanine; Animals; Benzamides; Binding Sites; Cell Line, Transformed; Diethylamines; HEK293 Cells; Humans; Ligands; Membrane Proteins; Mutation; Protein Binding; Protein Structure, Secondary; Rats; Receptors, Dopamine D2; Receptors, Dopamine D4; Salicylamides; Sodium; Structure-Activity Relationship; Threonine | 2012 |
Effect of trehalose on PC12 cells overexpressing wild-type or A53T mutant α-synuclein.
Topics: Adenine; Alanine; alpha-Synuclein; Animals; Autophagy; Blotting, Western; Cell Survival; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Lysosomes; Microscopy, Electron, Transmission; PC12 Cells; Phagosomes; Phosphoinositide-3 Kinase Inhibitors; Point Mutation; Proteasome Inhibitors; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles; Threonine; Transduction, Genetic; Trehalose; Up-Regulation | 2012 |
Screening for POLG W748S and A467T mutations in ataxia patients from Spain.
Topics: Adult; Age of Onset; Aged; Alanine; Ataxia; DNA Polymerase gamma; DNA-Directed DNA Polymerase; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Male; Middle Aged; Mutation; Polymorphism, Single Nucleotide; Serine; Spain; Threonine; Tryptophan; Young Adult | 2012 |
Selective lighting up of segments around Gly, Ala and Ser/Thr in proteins.
Topics: Alanine; Glycine; Humans; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Serine; Threonine; Ubiquitin | 2012 |
Fc receptor-γ subunits with both polar or non-polar amino acids at position of T22 are capable of restoring surface expression of the high-affinity IgE receptor and degranulation in γ subunit-deficient rat basophilic leukemia cells.
Topics: Alanine; Amino Acid Substitution; Animals; Basophils; Cell Degranulation; Cell Line, Tumor; Hydrogen Bonding; Leukemia, Basophilic, Acute; Mutant Proteins; Protein Interaction Domains and Motifs; Protein Subunits; Rats; Receptors, IgE; Recombinant Proteins; Serine; Signal Transduction; Threonine; Transfection | 2013 |
Relevance of the conserved histidine and asparagine residues in the phosphate-binding loop of the nucleotide binding subunit B of A₁A₀ ATP synthases.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Amino Acid Substitution; Archaeal Proteins; Asparagine; Binding Sites; Crystallography, X-Ray; Escherichia coli; Histidine; Methanosarcina; Molecular Docking Simulation; Protein Binding; Protein Subunits; Proton-Translocating ATPases; Recombinant Proteins; Substrate Specificity; Threonine | 2012 |
Effect of fatty acid-binding protein 2 Ala54Thr genotype on weight loss and cardiovascular risk factors after a high-polyunsaturated fat diet in obese patients.
Topics: Adult; Alanine; Caloric Restriction; Cardiovascular Diseases; Dietary Fats, Unsaturated; Fatty Acid-Binding Proteins; Fatty Acids, Unsaturated; Female; Follow-Up Studies; Genotype; Humans; Male; Middle Aged; Obesity; Risk Factors; Threonine; Weight Loss | 2012 |
What is influencing the phenotype of the common homozygous polymerase-γ mutation p.Ala467Thr?
Topics: Adolescent; Adult; Age of Onset; Alanine; Child; Cohort Studies; Diffuse Cerebral Sclerosis of Schilder; DNA Mutational Analysis; DNA Polymerase gamma; DNA-Directed DNA Polymerase; Europe; Family Health; Female; Genetic Predisposition to Disease; Homozygote; Humans; Male; Middle Aged; Mitochondrial Diseases; Muscle, Skeletal; Mutation; Ophthalmoplegia, Chronic Progressive External; Statistics as Topic; Statistics, Nonparametric; Threonine; Young Adult | 2012 |
[Myofibrillary myopathy due to the ZASP mutation Ala147Thr : two cases with exclusively distal leg involvement].
Topics: Adaptor Proteins, Signal Transducing; Aged; Alanine; Biopsy; Distal Myopathies; DNA Mutational Analysis; Female; Genetic Carrier Screening; Humans; LIM Domain Proteins; Magnetic Resonance Imaging; Muscle Weakness; Muscle, Skeletal; Muscular Dystrophies; Neurologic Examination; Phenotype; Threonine | 2013 |
Immunogenicity and cross protective ability of the central VP2 amino acids of infectious pancreatic necrosis virus in Atlantic salmon (Salmo salar L.).
Topics: Alanine; Amino Acids; Animals; Antibodies, Viral; Antigens, Viral; Cross Reactions; Fish Diseases; Host-Pathogen Interactions; Immunohistochemistry; Infectious pancreatic necrosis virus; Pancreas, Exocrine; Proline; Salmo salar; Survival Analysis; Survival Rate; Threonine; Time Factors; Vaccination; Vaccines, Attenuated; Vaccines, Inactivated; Viral Structural Proteins; Viral Vaccines | 2013 |
Higher cardiorespiratory fitness attenuates arterial stiffening associated with the Ala54Thr polymorphism in FABP2.
Topics: Adult; Alanine; Arteries; Base Sequence; Cardiovascular Physiological Phenomena; Cross-Sectional Studies; DNA Primers; Fatty Acid-Binding Proteins; Female; Humans; Male; Polymorphism, Single Nucleotide; Real-Time Polymerase Chain Reaction; Respiratory Physiological Phenomena; Threonine | 2013 |
On the existence of "L-threonine formate", "L-alanine lithium chloride" and "bis L-alanine lithium chloride" crystals.
Topics: Alanine; Crystallization; Lithium Chloride; Spectrophotometry, Infrared; Threonine | 2013 |
Functional studies of the Ciona intestinalis myogenic regulatory factor reveal conserved features of chordate myogenesis.
Topics: Alanine; Animals; Chordata; Ciona intestinalis; Gene Expression Regulation, Developmental; Models, Biological; Muscle Development; Muscles; Mutation; Myogenic Regulatory Factors; Notochord; Peptides; Protein Structure, Secondary; Protein Structure, Tertiary; Threonine | 2013 |
Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling.
Topics: Adaptor Proteins, Signal Transducing; Alanine; Animals; Culture Media, Conditioned; Dishevelled Proteins; Gene Expression Regulation; HEK293 Cells; Humans; Mutation; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins; Rats; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Wnt Proteins; Wnt-5a Protein; Wnt3A Protein | 2013 |
The role of the Ala746Thr variant in the ATP13A2 gene among Chinese patients with Parkinson's disease.
Topics: Age of Onset; Alanine; Asian People; Genetic Predisposition to Disease; Hong Kong; Humans; Middle Aged; Parkinson Disease; Proton-Translocating ATPases; Risk Factors; Threonine | 2013 |
Association study between FSHR Ala307Thr and Ser680Asn variants and polycystic ovary syndrome (PCOS) in Northern Chinese Han women.
Topics: Adult; Alanine; Amino Acid Substitution; Asian People; Asparagine; Case-Control Studies; China; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Geography; Humans; Mutation, Missense; Polycystic Ovary Syndrome; Polymorphism, Single Nucleotide; Receptors, FSH; Serine; Threonine | 2013 |
β-adrenergic regulation of the L-type Ca2+ channel does not require phosphorylation of α1C Ser1700.
Topics: Action Potentials; Adrenergic Agents; Alanine; Amino Acid Motifs; Animals; Calcium Channels, L-Type; Cyclic AMP-Dependent Protein Kinases; Mice; Mutation; Myocytes, Cardiac; Phosphorylation; Proteolysis; Rabbits; Serine; Threonine | 2013 |
Three most common nonsynonymous UGT1A6*2 polymorphisms (Thr181Ala, Arg184Ser and Ser7Ala) and therapeutic response to deferiprone in β-thalassemia major patients.
Topics: Adolescent; Alanine; Amino Acid Substitution; Arginine; beta-Thalassemia; Child; Child, Preschool; Deferiprone; Female; Gene Frequency; Genetic Association Studies; Glucuronosyltransferase; Humans; Iron Chelating Agents; Iron Overload; Isoenzymes; Male; Mutation, Missense; Polymorphism, Single Nucleotide; Pyridones; Serine; Threonine; Treatment Outcome | 2013 |
Structure-activity relationships of the N-terminus of calcitonin gene-related peptide: key roles of alanine-5 and threonine-6 in receptor activation.
Topics: Alanine; Animals; Arrestins; Calcitonin Gene-Related Peptide; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Humans; Isotope Labeling; Peptides; Protein Transport; Radioligand Assay; Radiopharmaceuticals; Receptors, Calcitonin Gene-Related Peptide; Salivary alpha-Amylases; Structure-Activity Relationship; Threonine; Transfection | 2014 |
Human protein aging: modification and crosslinking through dehydroalanine and dehydrobutyrine intermediates.
Topics: Adult; Aged, 80 and over; Alanine; Amino Acid Sequence; Aminobutyrates; Cell Nucleus; Cross-Linking Reagents; Crystallins; Glutathione; Humans; Lens, Crystalline; Middle Aged; Molecular Sequence Data; Peptides; Protein Processing, Post-Translational; Serine; Tandem Mass Spectrometry; Threonine; Time Factors | 2014 |
A chiral ligand exchange CE system for monitoring inhibitory effect of kojic acid on tyrosinase.
Topics: Alanine; beta-Cyclodextrins; Dansyl Compounds; Electrophoresis, Capillary; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Ligands; Monophenol Monooxygenase; Pyrones; Recombinant Proteins; Reproducibility of Results; Solutions; Soy Foods; Stereoisomerism; Threonine; Tyrosine; Zinc | 2013 |
Ala54Thr fatty acid-binding protein 2 (FABP2) polymorphism in recurrent depression: associations with fatty acid concentrations and waist circumference.
Topics: Adult; Alanine; Arachidonic Acid; Depressive Disorder, Major; Eicosanoic Acids; Erythrocytes; Fatty Acid-Binding Proteins; Fatty Acids; Female; Genotype; Humans; Male; Middle Aged; Polymorphism, Genetic; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Threonine; Waist Circumference | 2013 |
Type 2 deiodinase Thr92Ala polymorphism is associated with disrupted placental activity but not with dysglycemia or adverse gestational outcomes: a genetic association study.
Topics: Adolescent; Adult; Alanine; Blood Glucose; Cross-Sectional Studies; Female; Genetic Association Studies; Humans; Infant, Newborn; Insulin Resistance; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Middle Aged; Placenta; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Outcome; Threonine; Young Adult | 2014 |
Molecular characterization of an alanine-, proline-, glycine-, threonine-, and serine-rich protein of the hard tick Haemaphysalis qinghaiensis and its effect as a vaccine against tick infestation in sheep.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; DNA, Complementary; Glycine; Immunity, Active; Ixodidae; Molecular Sequence Data; Phylogeny; Proline; Rabbits; Recombinant Proteins; Sequence Analysis, DNA; Serine; Sheep; Sheep Diseases; Threonine; Tick Infestations; Vaccination; Vaccines | 2014 |
Amino acid derivatives as bitter taste receptor (T2R) blockers.
Topics: Alanine; Amino Acids; Asparagine; Binding Sites; GABA Agents; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Lysine; Models, Molecular; Molecular Structure; Mutation; Protein Binding; Protein Structure, Tertiary; Quinine; Receptors, G-Protein-Coupled; Taste; Threonine | 2014 |
Phenotype-genotype correlation in Wilson disease in a large Lebanese family: association of c.2299insC with hepatic and of p. Ala1003Thr with neurologic phenotype.
Topics: Adenosine Triphosphatases; Adolescent; Alanine; Cation Transport Proteins; Child; Child, Preschool; Consanguinity; Copper-Transporting ATPases; DNA Mutational Analysis; Exons; Female; Genetic Association Studies; Genotype; Hepatolenticular Degeneration; Humans; Infant; Lebanon; Male; Mutation; Pedigree; Phenotype; Threonine | 2014 |
Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation.
Topics: Aging; Alanine; Cell Line; DNA; DNA-Binding Proteins; HeLa Cells; Humans; Models, Molecular; Nuclear Proteins; Point Mutation; Progeria; Protein Conformation; Protein Stability; Threonine | 2014 |
MTHFR C677T and prothrombin G20210A mutations in a woman from Dalmatia with silent brain infarction. .
Topics: Alanine; Anticoagulants; Biomarkers; Brain Infarction; Croatia; Cysteine; Female; Glycine; Heterozygote; Homozygote; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Pedigree; Prothrombin; Threonine; Thrombophilia; Treatment Outcome | 2014 |
Prevalent polymorphism in thyroid hormone-activating enzyme leaves a genetic fingerprint that underlies associated clinical syndromes.
Topics: Adult; Alanine; Amino Acid Substitution; Case-Control Studies; Cerebral Cortex; Gene Frequency; HEK293 Cells; HeLa Cells; Humans; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Male; Microarray Analysis; Nervous System Diseases; Oxidative Stress; Polymorphism, Single Nucleotide; Syndrome; Threonine; Thyroid Diseases; Transcriptome | 2015 |
Substituting threonine 187 with alanine in p27Kip1 prevents pituitary tumorigenesis by two-hit loss of Rb1 and enhances humoral immunity in old age.
Topics: Age Factors; Alanine; Amino Acid Substitution; Animals; B-Lymphocytes; Carcinogenesis; Cyclin-Dependent Kinase Inhibitor p27; Erythrocytes; Flow Cytometry; Gene Knock-In Techniques; Germinal Center; Humans; Immunity, Humoral; Immunohistochemistry; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Pituitary Gland; Pituitary Neoplasms; Retinoblastoma Protein; Sheep; SKP Cullin F-Box Protein Ligases; T-Lymphocytes; Threonine | 2015 |
Human FABP1 T94A variant enhances cholesterol uptake.
Topics: Alanine; Amino Acid Substitution; Animals; Biological Transport; Cells, Cultured; Cholesterol; Fatty Acid-Binding Proteins; Female; Hepatocytes; Humans; Lipid Metabolism; Middle Aged; Mutation, Missense; Threonine | 2015 |
Increased Turnover at Limiting O2 Concentrations by the Thr(387) → Ala Variant of HIF-Prolyl Hydroxylase PHD2.
Topics: Alanine; Electron Spin Resonance Spectroscopy; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; Kinetics; Oxygen; Point Mutation; Recombinant Fusion Proteins; Threonine | 2015 |
PKB-Mediated Thr649 Phosphorylation of AS160/TBC1D4 Regulates the R-Wave Amplitude in the Heart.
Topics: Alanine; Animals; CD36 Antigens; Electrocardiography; Female; Gene Expression Regulation; Gene Knock-In Techniques; Glucose Transporter Type 4; GTPase-Activating Proteins; Heart Conduction System; Insulin; Male; Mice; Mice, Transgenic; Mutation; Myocardial Infarction; Myocardium; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; Signal Transduction; Threonine | 2015 |
Phosphorylation of Beet black scorch virus coat protein by PKA is required for assembly and stability of virus particles.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Beta vulgaris; Capsid Proteins; Cyclic AMP-Dependent Protein Kinases; Immunoblotting; Microscopy, Electron, Transmission; Molecular Sequence Data; Mutation; Nicotiana; Phosphorylation; Plant Diseases; Plant Viruses; Sequence Homology, Amino Acid; Threonine; Virion; Virulence; Virus Assembly | 2015 |
A genetic association study of two genes linked to neurodegeneration in a Sardinian multiple sclerosis population: the TARDBP Ala382Thr mutation and C9orf72 expansion.
Topics: Adult; Aged; Aged, 80 and over; Alanine; C9orf72 Protein; Cohort Studies; DNA Repeat Expansion; DNA-Binding Proteins; Female; Follow-Up Studies; Genetic Association Studies; Humans; Italy; Male; Middle Aged; Multiple Sclerosis; Mutation, Missense; Neurodegenerative Diseases; Population Surveillance; Proteins; Threonine | 2015 |
Amyloid β-Protein Assembly: Differential Effects of the Protective A2T Mutation and Recessive A2V Familial Alzheimer's Disease Mutation.
Topics: Alanine; Alzheimer Disease; Amino Acid Substitution; Amyloid beta-Peptides; Humans; Hydrophobic and Hydrophilic Interactions; Mass Spectrometry; Microscopy, Electron, Transmission; Mutation; Peptide Fragments; Protein Structure, Secondary; Threonine; Valine | 2015 |
Phosphorylation of TRPV1 by cyclin-dependent kinase 5 promotes TRPV1 surface localization, leading to inflammatory thermal hyperalgesia.
Topics: Alanine; Animals; Calcium; Cells, Cultured; Cyclin-Dependent Kinase 5; Disease Models, Animal; Freund's Adjuvant; Ganglia, Spinal; Humans; Hyperalgesia; Inflammation; Kinesins; Male; Mutation; Neurons; Peptides; Phosphorylation; Phosphotransferases; Rats; Rats, Sprague-Dawley; Threonine; TRPV Cation Channels | 2015 |
Identification of lanthionine and lysinoalanine in heat-treated wheat gliadin and bovine serum albumin using tandem mass spectrometry with higher-energy collisional dissociation.
Topics: Alanine; Animals; Cattle; Chymotrypsin; Cysteine; Cystine; Gliadin; Hot Temperature; Hydrogen-Ion Concentration; Lysine; Lysinoalanine; Proteolysis; Serum Albumin, Bovine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfides; Threonine; Triticum; Trypsin | 2016 |
The Ala54Thr Polymorphism of the Fatty Acid Binding Protein 2 Gene Modulates HDL Cholesterol in Mexican-Americans with Type 2 Diabetes.
Topics: Adult; Aged; Alanine; Biomarkers; Blood Glucose; Cholesterol, HDL; Diabetes Mellitus, Type 2; Fatty Acid-Binding Proteins; Female; Genetic Markers; Humans; Male; Mexican Americans; Middle Aged; Polymorphism, Single Nucleotide; Threonine; United States | 2015 |
Dynamic Changes in Striatal mGluR1 But Not mGluR5 during Pathological Progression of Parkinson's Disease in Human Alpha-Synuclein A53T Transgenic Rats: A Multi-PET Imaging Study.
Topics: Alanine; alpha-Synuclein; Animals; Corpus Striatum; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Agents; Exploratory Behavior; Female; Humans; Motor Activity; Oximes; Parkinson Disease; Protein Binding; Pyridines; Radioisotopes; Radionuclide Imaging; Rats; Rats, Transgenic; Receptors, Metabotropic Glutamate; Threonine; Time Factors | 2016 |
A2T and A2V Aβ peptides exhibit different aggregation kinetics, primary nucleation, morphology, structure, and LTP inhibition.
Topics: Alanine; Amino Acid Substitution; Amyloid beta-Peptides; Animals; Hippocampus; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Long-Term Potentiation; Mice; Microscopy, Atomic Force; Microtomy; Mutation; Peptide Fragments; Protein Aggregates; Protein Binding; Protein Folding; Protein Multimerization; Protein Stability; Threonine; Valine | 2016 |
Mutational screening of the INSL3 gene in azoospermic males with a history of cryptorchidism.
Topics: Adult; Alanine; Azoospermia; Base Sequence; Biopsy; Case-Control Studies; China; Cryptorchidism; Exons; Genetic Association Studies; Humans; Insulin; Male; Mutation; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Proteins; Semen Analysis; Sequence Analysis, DNA; Spermatogenesis; Testis; Threonine | 2016 |
Age-dependent neuroinflammation and cognitive decline in a novel Ala152Thr-Tau transgenic mouse model of PSP and AD.
Topics: Age Factors; Aging; Alanine; Alzheimer Disease; Animals; Astrocytes; Cognition Disorders; Cytokines; Dendritic Spines; Disease Models, Animal; Encephalitis; Female; Humans; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Pneumothorax; RNA, Untranslated; tau Proteins; Threonine | 2016 |
Failure of RQC machinery causes protein aggregation and proteotoxic stress.
Topics: Alanine; Codon, Terminator; Inclusion Bodies; Molecular Chaperones; Polylysine; Proteasome Endopeptidase Complex; Protein Aggregates; Protein Aggregation, Pathological; Protein Biosynthesis; Proteolysis; Ribosomes; RNA-Binding Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Stress, Physiological; Threonine; Ubiquitin-Protein Ligases | 2016 |
Rqc1 and Ltn1 Prevent C-terminal Alanine-Threonine Tail (CAT-tail)-induced Protein Aggregation by Efficient Recruitment of Cdc48 on Stalled 60S Subunits.
Topics: Adenosine Triphosphatases; Alanine; Blotting, Western; Cell Cycle Proteins; Microscopy, Fluorescence; Mutation; Proteasome Endopeptidase Complex; Protein Aggregates; Protein Biosynthesis; Proteolysis; Proteomics; Ribosome Subunits, Large, Eukaryotic; RNA-Binding Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Threonine; Ubiquitin-Protein Ligases; Ubiquitination; Valosin Containing Protein | 2016 |
Effects of straight alkyl chain, extra hydroxylated alkyl chain and branched chain amino acids on gastric emptying evaluated using a non-invasive breath test in conscious rats.
Topics: Acetic Acid; Administration, Oral; Alanine; Amino Acids; Amino Acids, Branched-Chain; Animals; Breath Tests; Consciousness; Gastric Emptying; Glycine; Isoleucine; Leucine; Male; Rats, Sprague-Dawley; Serine; Threonine; Valine | 2016 |
Phylogenetic analysis of the NS5 gene of Zika virus.
Topics: Aedes; Alanine; Animals; Humans; Mexico; Mutation; Panama; Phylogeny; RNA, Viral; South America; Threonine; Viral Nonstructural Proteins; Viral Tropism; Zika Virus; Zika Virus Infection | 2016 |
Characterization of CTX-M-140, a Variant of CTX-M-14 Extended-Spectrum β-Lactamase with Decreased Cephalosporin Hydrolytic Activity, from Cephalosporin-Resistant Proteus mirabilis.
Topics: Alanine; Amino Acid Substitution; Anti-Bacterial Agents; Base Composition; beta-Lactamases; Cephalosporins; Cloning, Molecular; Drug Resistance, Bacterial; Escherichia coli; Gene Expression; Genome Size; Genome, Bacterial; Hydrolysis; Isoenzymes; Microbial Sensitivity Tests; Mutation; Proteus mirabilis; Recombinant Proteins; Threonine | 2016 |
A Cryptochrome 2 mutation yields advanced sleep phase in humans.
Topics: Alanine; Amino Acid Substitution; Animals; Cryptochromes; F-Box Proteins; Humans; Mice; Mutant Proteins; Mutation, Missense; Protein Conformation; Proteolysis; Sleep Disorders, Circadian Rhythm; Threonine; Ubiquitination | 2016 |
Intestinal fatty acid binding protein Ala54Thr polymorphism is associated with peripheral atherosclerosis combined with type 2 diabetes mellitus.
Topics: Adult; Alanine; Case-Control Studies; Diabetes Mellitus, Type 2; Egypt; Enzyme-Linked Immunosorbent Assay; Fatty Acid-Binding Proteins; Gene Frequency; Heterozygote; Humans; Middle Aged; Peripheral Arterial Disease; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Threonine | 2017 |
Impairment of mitochondria dynamics by human A53T α-synuclein and rescue by NAP (davunetide) in a cell model for Parkinson's disease.
Topics: Alanine; alpha-Synuclein; Cell Differentiation; Cell Line, Tumor; Gene Expression Regulation; Humans; Kymography; Luminescent Proteins; Membrane Potential, Mitochondrial; Microtubule-Associated Proteins; Mitochondria; Neuroblastoma; Oligopeptides; Reactive Oxygen Species; RNA, Messenger; Threonine; Transfection | 2017 |
Genetic polymorphisms in extracellular superoxide dismutase Leu53Leu, Arg213Gly, and Ala40Thr and susceptibility to type 2 diabetes mellitus.
Topics: Adult; Alanine; Arginine; Asian People; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Leucine; Male; Middle Aged; Polymorphism, Single Nucleotide; Regression Analysis; Superoxide Dismutase; Threonine | 2016 |
Alzheimer's Protective Cross-Interaction between Wild-Type and A2T Variants Alters Aβ
Topics: Alanine; Alzheimer Disease; Amino Acid Substitution; Amyloid beta-Peptides; Animals; Humans; Kinetics; Models, Molecular; Molecular Dynamics Simulation; Monte Carlo Method; Mutation; Peptide Fragments; Protein Multimerization; Protein Structure, Secondary; Threonine | 2017 |
Semi-microbiological synthesis of an active lysinoalanine-bridged analog of glucagon-like-peptide-1.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Glucagon-Like Peptide 1; Hydro-Lyases; Lactococcus lactis; Lysinoalanine; Membrane Proteins; Membrane Transport Proteins; Protein Processing, Post-Translational; SEC Translocation Channels; Serine; Substrate Specificity; Threonine | 2017 |
Low Florbetapir PET Uptake and Normal Aβ1-42 Cerebrospinal Fluid in an APP Ala713Thr Mutation Carrier.
Topics: Alanine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Aniline Compounds; Brain; Ethylene Glycols; Humans; Male; Middle Aged; Mutation; Peptide Fragments; Positron-Emission Tomography; Threonine | 2017 |
Threonine eliminylation by bacterial phosphothreonine lyases rapidly causes cross-linking of mitogen-activated protein kinase (MAPK) in live cells.
Topics: Alanine; Aminobutyrates; Animals; Antibodies; Bacterial Proteins; Caco-2 Cells; Carbon-Oxygen Lyases; Cell Line; Extracellular Signal-Regulated MAP Kinases; HeLa Cells; Humans; MAP Kinase Signaling System; Mice; p38 Mitogen-Activated Protein Kinases; Protein Binding; Proteomics; Shigella; Substrate Specificity; Threonine; Type III Secretion Systems | 2017 |
Quantitative chiral analysis of amino acids in solution using enantiomer-selective photodissociation of cold gas-phase tryptophan via chiral recognition.
Topics: Alanine; Amino Acids; Serine; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Threonine; Tryptophan | 2017 |
CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides.
Topics: Alanine; Lysine; Peptides; Proteolysis; Proteostasis; Ribosomes; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Threonine; Transcription Elongation, Genetic; Ubiquitin; Ubiquitin-Protein Ligases | 2017 |
The N-terminal peptide moiety of the Mycobacterium tuberculosis 19 kDa lipoprotein harbors RP105-agonistic properties.
Topics: Alanine; Animals; Antigens, CD; Bacterial Proteins; Host Microbial Interactions; Lipopeptides; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Mycobacterium tuberculosis; Primary Cell Culture; Threonine; Toll-Like Receptor 2; Tuberculosis | 2018 |
Identification of a novel mutation (Ala66Thr) of SRY gene causes XY pure gonadal dysgenesis by affecting DNA binding activity and nuclear import.
Topics: Active Transport, Cell Nucleus; Adolescent; Adult; Alanine; DNA; Female; Gonadal Dysgenesis, 46,XY; HEK293 Cells; Humans; Karyotyping; Male; Mutation, Missense; Protein Binding; Protein Conformation; Sequence Analysis, DNA; Sex-Determining Region Y Protein; Threonine; Young Adult | 2018 |
A chiral selectivity relaxed paralog of DTD for proofreading tRNA mischarging in Animalia.
Topics: Alanine; Amino Acid Sequence; Aminoacyltransferases; Animals; Apicomplexa; Bacteria; Binding Sites; Biological Evolution; Cloning, Molecular; Crystallography, X-Ray; Gene Expression; Humans; Models, Molecular; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; RNA, Transfer, Amino Acyl; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Threonine; Transfer RNA Aminoacylation | 2018 |
Effects of Ginkgo Biloba Extract on A53T α-Synuclein Transgenic Mouse Models of Parkinson's Disease.
Topics: Alanine; alpha-Synuclein; Animals; Antiparkinson Agents; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Ginkgo biloba; Glutathione; Glutathione Peroxidase; Locomotion; Malondialdehyde; Mice; Mice, Transgenic; Muscle Strength; Mutation; Parkinson Disease; Plant Extracts; Superoxide Dismutase; Swimming; Threonine | 2018 |
T300A variant of AT16L1 gene in a cohort of Algerian Crohn disease patients.
Topics: Adolescent; Adult; Age of Onset; Alanine; Algeria; Amino Acid Substitution; Autophagy-Related Proteins; Case-Control Studies; Cohort Studies; Crohn Disease; Female; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Mutation, Missense; Polymorphism, Single Nucleotide; Severity of Illness Index; Threonine; Young Adult | 2018 |
Inverted allosteric coupling between activation and inactivation gates in K
Topics: Alanine; Allosteric Regulation; Bacterial Proteins; Crystallography, X-Ray; HEK293 Cells; Humans; Ion Channel Gating; Models, Molecular; Mutation; Potassium; Potassium Channels; Protein Conformation; Threonine | 2018 |
A53T-α-synuclein overexpression in murine locus coeruleus induces Parkinson's disease-like pathology in neurons and glia.
Topics: Alanine; alpha-Synuclein; Animals; Calcium-Binding Proteins; Disease Models, Animal; Endopeptidase K; Humans; Locus Coeruleus; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Mutation; Nerve Tissue Proteins; Neuroglia; Neurons; Parkinson Disease; Protein Aggregates; Protein Transport; Threonine; Time Factors; Transduction, Genetic; Tyrosine 3-Monooxygenase | 2018 |
Quantification of thioether-linked glutathione modifications in human lens proteins.
Topics: Adolescent; Alanine; Aminobutyrates; Cataract; Cellular Senescence; Chromatography, Liquid; Crystallins; Cysteine; Glutathione; Humans; Lens, Crystalline; Middle Aged; Protein Processing, Post-Translational; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfides; Threonine; Tissue Donors; Young Adult | 2018 |
123I-FP-CIT SPECT [(123) I-2β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl) nortropane single photon emission computed tomography] Imaging in a p.A53T α-synuclein Parkinson's disease cohort versus Parkinson's disease.
Topics: Adult; Alanine; alpha-Synuclein; Cognition Disorders; Cohort Studies; Corpus Striatum; Dopamine; Female; Functional Laterality; Humans; Male; Middle Aged; Mutation; Parkinson Disease; Threonine; Tomography, Emission-Computed, Single-Photon; Tropanes | 2018 |
Bioformation of Volatile and Nonvolatile Metabolites by
Topics: Acetates; Alanine; Carbon; Glutamic Acid; Glycine; Isoleucine; Mannitol; Mannose; Phenylacetates; Phenylalanine; Phenylethyl Alcohol; Proline; Saccharomycopsis; Serine; Sugar Alcohols; Threonine; Time Factors | 2018 |
Histopathology of the Inner Ear in Charcot-Marie-Tooth Syndrome Caused by a Missense Variant (p.Thr65Ala) in the MPZ Gene.
Topics: Aged; Alanine; Charcot-Marie-Tooth Disease; Chromosome Aberrations; Cochlear Nerve; Ear, Inner; Exome Sequencing; Facial Nerve; Genes, Dominant; Genetic Variation; Humans; Male; Mutation, Missense; Myelin P0 Protein; Myelin Sheath; Threonine; Vestibular Nerve | 2018 |
CAT tails drive degradation of stalled polypeptides on and off the ribosome.
Topics: Alanine; Peptides; Protein Biosynthesis; Proteolysis; Ribosomes; RNA-Binding Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Threonine; Ubiquitin-Protein Ligases | 2019 |
A modifier in the 129S2/SvPasCrl genome is responsible for the viability of Notch1[12f/12f] mice.
Topics: Alanine; Amino Acid Substitution; Animals; Embryo, Mammalian; Embryonic Development; Female; Fucose; Genes, Modifier; Genome; Homozygote; Inbreeding; Male; Mice; Mice, Inbred C57BL; Phenotype; Protein Domains; Receptor, Notch1; Threonine | 2019 |
Behavioural and dopaminergic changes in double mutated human A30P*A53T alpha-synuclein transgenic mouse model of Parkinson´s disease.
Topics: Aging; Alanine; alpha-Synuclein; Amino Acid Substitution; Animals; Behavior, Animal; Disease Models, Animal; Dopaminergic Neurons; Humans; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation, Missense; Parkinson Disease; Proline; Threonine | 2019 |
Aggregation of CAT tails blocks their degradation and causes proteotoxicity in S. cerevisiae.
Topics: Alanine; DNA Polymerase III; Peptides; Proteasome Endopeptidase Complex; Protein Biosynthesis; Proteolysis; Ribosomes; RNA-Binding Proteins; RNA, Transfer; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Threonine; Ubiquitin; Ubiquitin-Protein Ligases | 2020 |
Identification of Ala2Thr mutation in insulin gene from a Chinese MODY10 family.
Topics: Adult; Alanine; Cell Line; China; Diabetes Mellitus, Type 2; Endoplasmic Reticulum Stress; Family Health; Female; Genetic Predisposition to Disease; Glucose; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Mutation; Mutation, Missense; Pedigree; Protein Structure, Secondary; Structure-Activity Relationship; Threonine; Young Adult | 2020 |
Thr92Ala polymorphism in the type 2 deiodinase gene: an evolutionary perspective.
Topics: Alanine; Alleles; Amino Acid Substitution; Animals; Evolution, Molecular; Gene Frequency; Genetics, Population; Geography; History, Ancient; Humans; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Neanderthals; Polymorphism, Single Nucleotide; Threonine | 2020 |
Cross-editing by a tRNA synthetase allows vertebrates to abundantly express mischargeable tRNA without causing mistranslation.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Evolution, Molecular; HEK293 Cells; Humans; RNA Editing; RNA, Transfer; Threonine; Vertebrates | 2020 |
Failure to Degrade CAT-Tailed Proteins Disrupts Neuronal Morphogenesis and Cell Survival.
Topics: Alanine; Antigens, Neoplasm; Cell Line; Cell Survival; HEK293 Cells; HeLa Cells; Humans; Morphogenesis; Neurons; Nucleocytoplasmic Transport Proteins; Peptides; Protein Biosynthesis; Proteolysis; Ribosomes; RNA-Binding Proteins; RNA, Messenger; Threonine; Ubiquitin-Protein Ligases; Ubiquitination | 2021 |
Impact of immune checkpoint gene CD155 Ala67Thr and CD226 Gly307Ser polymorphisms on small cell lung cancer clinical outcome.
Topics: Aged; Alanine; Amino Acid Substitution; Antigens, Differentiation, T-Lymphocyte; Carcinoma, Small Cell; Female; Glycine; Humans; Lung Neoplasms; Male; Polymorphism, Genetic; Receptors, Virus; Serine; Threonine; Treatment Outcome | 2021 |
Comprehensively understanding metabolic pathways of protein during the anaerobic digestion of waste activated sludge.
Topics: Acetyl Coenzyme A; Alanine; Amino Acids; Anaerobiosis; Arginine; Glutamates; Glycine; Histidine; Leucine; Lysine; Metabolic Networks and Pathways; Methionine; Phenylalanine; Pyruvic Acid; Serine; Sewage; Threonine; Tyrosine | 2022 |
Neurite Outgrowth-Promoting Compounds from Cockscomb Hydrolysate.
Topics: Alanine; Amino Acids; Animals; Methionine; Neurites; Neuronal Outgrowth; PC12 Cells; Rats; Threonine; Valine | 2022 |
The impact of phosphorylated PTEN at threonine 366 on cortical connectivity and behaviour.
Topics: Alanine; Animals; Lipids; Male; Mice; Neurons; PTEN Phosphohydrolase; Tensins; Threonine | 2022 |
Isolation and characterization of novel antihypertensive bioactive peptides from brassica napus and angiotensin-converting enzyme (ace) inhibition potential.
Topics: Alanine; Angiotensins; Antihypertensive Agents; Arginine; Brassica napus; Cysteine; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptides; Peptidyl-Dipeptidase A; Phenylalanine; Proline; Tandem Mass Spectrometry; Threonine; Tyrosine; Valine | 2022 |
Blunted Amphetamine-induced Reinforcing Behaviors and Transporter Downregulation in Knock-in Mice Carrying Alanine Mutations at Threonine-258 and Serine-259 of Norepinephrine Transporter.
Topics: Alanine; Amphetamine; Animals; Down-Regulation; Male; Membrane Transport Proteins; Mice; Mutation; Norepinephrine Plasma Membrane Transport Proteins; Serine; Threonine | 2022 |
Role of the gut-microbiota-metabolite axis in the rotenone model of early-stage Parkinson's Disease.
Topics: Alanine; Animals; Asparagine; Gastrointestinal Microbiome; Glutamine; Hydroxyproline; Methionine; Mice; Parkinson Disease; Rotenone; Serine; Threonine | 2022 |
The combination of microbiome and metabolome to analyze the cross-cooperation mechanism of
Topics: Alanine; Animals; Echinacea; Fatty Acids, Volatile; Gastrointestinal Microbiome; Glycine; Glycosphingolipids; Humans; Leucine; Metabolome; Mice; Microbiota; Ornithine; Phenylalanine; Polysaccharides; Porphyrins; Serine; Threonine; Tryptophan; Tyrosine | 2022 |
Recent strains of influenza D virus create a new genetic cluster for European strains.
Topics: Alanine; Animals; Arginine; Asparagine; Aspartic Acid; Cattle; Cattle Diseases; Glycine; Nucleotides; Orthomyxoviridae; Orthomyxoviridae Infections; Phylogeny; Proline; Serine; Thogotovirus; Threonine; Valine | 2022 |
NMR-Based Metabolomic Analysis for the Effects of Trimethylamine N-Oxide Treatment on C2C12 Myoblasts under Oxidative Stress.
Topics: Alanine; Catalase; Diabetes Mellitus, Type 2; Glycine; Histidine; Humans; Hydrogen Peroxide; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Malondialdehyde; Methylamines; Myoblasts; Oxidative Stress; Phenylalanine; Phosphorylcholine; Superoxide Dismutase; Threonine; Valine | 2022 |
Unveiling the Essential Role of Arkadia's Non-RING Elements in the Ubiquitination Process.
Topics: Alanine; Arginine; Asparagine; Glutamine; Glycine; Isoleucine; Threonine; Transforming Growth Factor beta; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitination | 2022 |
NMR-Based Metabolomic Analysis of Cardiac Tissues Clarifies Molecular Mechanisms of CVB3-Induced Viral Myocarditis and Dilated Cardiomyopathy.
Topics: Alanine; Animals; Aspartic Acid; Biomarkers; Cardiomyopathy, Dilated; Coxsackievirus Infections; Enterovirus B, Human; Glutamic Acid; Glutamine; Glycine; Mice; Mice, Inbred BALB C; Myocarditis; Niacin; Niacinamide; Serine; Taurine; Threonine | 2022 |
[Determination of free amino acids in Eriocheir sinensis by ultra-high performance liquid chromatography-high resolution mass spectrometry].
Topics: Acetonitriles; Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brachyura; Chromatography, High Pressure Liquid; Cystine; Formates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Mass Spectrometry; Methionine; Perchlorates; Phenylalanine; Polypropylenes; Proline; Serine; Solvents; Threonine; Tyrosine; Valine; Water | 2022 |
Preferential Adsorption of Prominent Amino Acids in the Urease Enzyme of
Topics: Adsorption; Alanine; Aluminum Oxide; Amino Acids; Aspartic Acid; Calcium Carbonate; Carbonates; Glutamates; Glycine; Quartz; Soil; Threonine; Urease | 2022 |
Benincasa hispida extracts positively regulated high salt-induced hypertension in Dahl salt-sensitive rats: Impact on biochemical profile and metabolic patterns.
Topics: Alanine; Amino Acids; Animals; Antihypertensive Agents; Antioxidants; Aspartic Acid; Cucurbitaceae; Glycine; Hypertension; Phenylalanine; Plant Extracts; Rats; Rats, Inbred Dahl; Renal Insufficiency; Serine; Sodium Chloride; Sodium Chloride, Dietary; Threonine; Tyrosine | 2022 |
Metabolic pathway analysis of hyperuricaemia patients with hyperlipidaemia based on high-throughput mass spectrometry: a case‒control study.
Topics: Alanine; Aspartic Acid; Biomarkers; Case-Control Studies; Glycine; Humans; Hyperlipidemias; Hyperuricemia; Linoleic Acid; Mass Spectrometry; Metabolic Diseases; Metabolic Networks and Pathways; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine | 2022 |
Metabolomics profiling of seminal plasma in obesity-induced asthenozoospermia.
Topics: Aconitic Acid; Alanine; Asthenozoospermia; Citrulline; Glucose; Glutamic Acid; Glycine; Humans; Leucine; Lysine; Male; Metabolomics; Phenylalanine; Proline; Semen; Serine; Succinic Acid; Threonine; Tyrosine; Valine | 2023 |
The Association between Macrosomia and Amino Acids' Levels in Maternal and Cord Sera: A Case-Control Study.
Topics: Alanine; Amino Acids; Arginine; Case-Control Studies; Chromatography, Liquid; Female; Fetal Macrosomia; Glutamic Acid; Glutamine; Histidine; Humans; Infant, Newborn; Leucine; Methionine; Tandem Mass Spectrometry; Threonine; Tryptophan; Valine | 2023 |
Transcriptomics integrated with metabolomics reveals perfluorobutane sulfonate (PFBS) exposure effect during pregnancy and lactation on lipid metabolism in rat offspring.
Topics: Alanine; Animals; Aspartic Acid; Cytochrome P-450 Enzyme System; Female; Gene Expression Profiling; Glycine; Lactation; Lipid Metabolism; Metabolomics; Pantetheine; Phosphates; Pregnancy; Rats; Serine; Threonine; Transcriptome; Xenobiotics | 2023 |
Integration of semi-empirical MS/MS library with characteristic features for the annotation of novel amino acid-conjugated bile acids.
Topics: Alanine; Amino Acids; Animals; Bile Acids and Salts; Chromatography, Liquid; Dogs; Glycine; Humans; Leucine; Lysine; Methionine; Mice; Rats; Tandem Mass Spectrometry; Threonine; Tyrosine | 2023 |
Detection and identification of amino acids and proteins using their intrinsic fluorescence in the visible light spectrum.
Topics: Alanine; Amino Acids; Arginine; Cystine; Fluorescence; Glycine; Leucine; Methionine; Proteins; Serine; Threonine; Tyrosine; Valine | 2023 |
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |