alanine and sq 28603

alanine has been researched along with sq 28603 in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's34 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cernacek, P; Farber, D; Legault, L; Levy, M; Maher, E1
Abboa-Offei, BE; Asaad, MM; Fennell, S; Rogers, WL; Rovnyak, PL; Seymour, AA1
Bennett, T; Gardiner, SM; Kemp, PA1
Abassi, ZA; Hunsberger, S; Keiser, HR; Klein, H; Tate, J; Trachewsky, D1
Gardner, D; Humphreys, MH; Qiu, CB; Valentin, JP; Wiedemann, E1
Burnett, JC; Margulies, KB; McKinley, LJ; Perrella, MA1
Abboa-Offei, B; Asaad, MM; Rogers, WL; Seymour, AA1
Asaad, MM; Fennell, SA; Kratunis, VJ; Little, DK; Norman, JA; Rogers, WL; Seymour, AA1
Asaad, MM; Gabel, RA; Harvey, CM; Rogers, WL; Trippodo, NC1
Abboa-Offei, B; Asaad, MM; Delaney, NG; Di Donato, G; Fennell, SA; Hunt, JT; Kratunis, VJ; Little, DK; Norman, JA; Seymour, AA1
Cohen, RB; Dickinson, KE; Hedberg, A; Liu, EC; Tymiak, AA; Webb, ML1
Burnett, JC; Cavero, PG; Delaney, NG; Margulies, KB; Seymour, AA1
Asaad, MM; Rogers, WL; Seymour, AA; Sheldon, JH; Smith, PL1
Asaad, MM; Dorso, CR; Moreland, SM1
Bird, JE; Waldron, TL1
Abboa-Offei, BE; Asaad, MM; Mathers, PD; Rogers, WL; Seymour, AA; Smith, PL1
Abassi, ZA; Golomb, E; Keiser, HR; Kotob, S; Pieruzzi, F1
Fox, M; Panchal, BC; Trippodo, NC1
Abboa-Offei, B; Asaad, MM; Rogers, WL; Seymour, AA; Smith, PL1
Asaad, M; Rogers, WL; Seymour, AA; Sheldon, JH; Smith, PL1
Asaad, MM; Cheung, HS; Fennell, SA; Lanoce, VM; Rogers, WL; Seymour, AA1
Asaad, MM; Dorso, CR; Fox, M; Natarajan, V; Panchal, BC; Trippodo, NC1
Asaad, MM; Fennell, SA; Langenbacher, KM; Lanoce, VM; Rogers, WL; Seymour, AA1
Abassi, ZA; Bridenbaugh, R; Golomb, E; Keiser, HR1
Bralet, J; Lecomte, JM; Marie, C; Mossiat, C; Schwartz, JC1
Allen, GT; Powell, JR; Tesfamariam, B1
Abboa-Offei, BE; Asaad, MM; Dorso, CR; Rogers, WL; Seymour, AA; Smith, PL1
Dietz, R; Höhnel, K; Luft, FC; Scheuermann, M; Willenbrock, R1
D'Orléans-Juste, P; Fournier, A; Lebel, N; Sirois, P1
Chakir, M; D'Orléans-Juste, P; Plante, GE1
Abboa-Offei, BE; Asaad, MM; Mathers, PD; Seymour, AA; Weber, H1
Bralet, J; Gros, C; Marie, C; Monteil, T; Mossiat, C1
Dietz, R; Scheuermann, M; Willenbrock, R1
Blumberg, S; Fudim, E; Gurbanov, K; Kaballa, A; Shuranyi, E; Winaver, J1

Reviews

1 review(s) available for alanine and sq 28603

ArticleYear
Potentiation of natriuretic peptides by neutral endopeptidase inhibitors.
    Clinical and experimental pharmacology & physiology, 1995, Volume: 22, Issue:1

    Topics: Alanine; Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Heart Failure; Hemodynamics; Hypertension; Neprilysin

1995

Other Studies

33 other study(ies) available for alanine and sq 28603

ArticleYear
Renal tubular responsiveness to atrial natriuretic peptide in sodium-retaining chronic caval dogs. A possible role for kinins and luminal actions of the peptide.
    The Journal of clinical investigation, 1992, Volume: 90, Issue:4

    Topics: Alanine; Animals; Ascites; Atrial Natriuretic Factor; Chronic Disease; Cyclic GMP; Dogs; Female; Kidney Tubules; Kinins; Male; Neprilysin; Protease Inhibitors; Receptors, Bradykinin; Receptors, Neurotransmitter; Sodium

1992
Potentiation of brain natriuretic peptides by SQ 28,603, an inhibitor of neutral endopeptidase 3.4.24.11, in monkeys and rats.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:1

    Topics: Alanine; Animals; Atrial Natriuretic Factor; Brain; Diuresis; Drug Synergism; Female; Macaca fascicularis; Male; Natriuretic Peptide, Brain; Neprilysin; Nerve Tissue Proteins; Rats; Rats, Inbred SHR; Sodium; Species Specificity

1992
Effects of the neutral endopeptidase inhibitor, SQ 28,603, on regional haemodynamic responses to atrial natriuretic peptide or proendothelin-1 [1-38] in conscious rats.
    British journal of pharmacology, 1992, Volume: 106, Issue:1

    Topics: Alanine; Angiotensin I; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Endothelin-1; Endothelins; Heart Rate; Injections, Intravenous; Male; Neprilysin; Protein Precursors; Rats

1992
Pharmacokinetics of ANF and urodilatin during cANF receptor blockade and neutral endopeptidase inhibition.
    The American journal of physiology, 1992, Volume: 263, Issue:5 Pt 1

    Topics: Alanine; Animals; Atrial Natriuretic Factor; Male; Natriuresis; Neprilysin; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Atrial Natriuretic Factor

1992
Inhibition of neutral endopeptidase amplifies the effects of endogenous atrial natriuretic peptide on blood pressure and fluid partition.
    American journal of hypertension, 1992, Volume: 5, Issue:2

    Topics: Alanine; Animals; Atrial Natriuretic Factor; Blood Pressure; Blood Proteins; Blood Volume; Hematocrit; Infusions, Intravenous; Male; Neprilysin; Osmolar Concentration; Rats; Rats, Inbred Strains

1992
Angiotensin inhibition potentiates the renal responses to neutral endopeptidase inhibition in dogs with congestive heart failure.
    The Journal of clinical investigation, 1991, Volume: 88, Issue:5

    Topics: Alanine; Angiotensin II; Animals; Atrial Natriuretic Factor; Cyclic GMP; Dogs; Heart Failure; Hemodynamics; Kidney; Male; Neprilysin; Sodium

1991
Evaluation of SQ 28,603, an inhibitor of neutral endopeptidase, in conscious monkeys.
    Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:10

    Topics: Alanine; Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Diuresis; Diuretics; Female; Hemodynamics; Kidney; Macaca fascicularis; Natriuresis; Neprilysin; Peptide Fragments; Sodium

1991
Antihypertensive and renal activity of SQ 28,603, an inhibitor of neutral endopeptidase.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:2

    Topics: Alanine; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Cyclic GMP; Desoxycorticosterone; Diuresis; Hypertension; Infusions, Intravenous; Injections, Intravenous; Kidney; Male; Natriuresis; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains; Sodium Chloride

1991
Heart failure augments the cardiovascular and renal effects of neutral endopeptidase inhibition in rats.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:3

    Topics: Alanine; Animals; Blood Pressure; Body Weight; Central Venous Pressure; Heart Failure; Heart Rate; Hemodynamics; Kidney; Male; Myocardial Infarction; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains

1991
Possible regulation of atrial natriuretic factor by neutral endopeptidase 24.11 and clearance receptors.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:3

    Topics: Alanine; Animals; Atrial Natriuretic Factor; Blood Pressure; Desoxycorticosterone; Hypertension; Male; Neprilysin; Peptide Fragments; Rats; Rats, Inbred Strains

1991
Vascular A10 cell membranes contain an endothelin metabolizing neutral endopeptidase.
    Biochemical and biophysical research communications, 1991, Apr-15, Volume: 176, Issue:1

    Topics: Alanine; Animals; Aorta; Cell Line; Cell Membrane; Endothelins; Glycopeptides; Kidney; Kinetics; Microvilli; Muscle, Smooth, Vascular; Neprilysin; Rats; Thiorphan

1991
Neutral endopeptidase inhibition potentiates the renal actions of atrial natriuretic factor.
    Kidney international, 1990, Volume: 38, Issue:1

    Topics: Alanine; Animals; Atrial Natriuretic Factor; Dogs; Glomerular Filtration Rate; Kidney; Natriuresis; Neprilysin; Renal Circulation

1990
Atrial natriuretic peptide in chronically hypertensive dogs.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:4

    Topics: Alanine; Animals; Atrial Natriuretic Factor; Blood Pressure; Chronic Disease; Diuretics; Dogs; Female; Humans; Hypertension, Renovascular; Injections, Intravenous; Kidney; Male; Neprilysin; Peptide Fragments

1995
Effects of neutral endopeptidase inhibition on the clearance of exogenously administered endothelin in Sprague-Dawley rats.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:4

    Topics: Alanine; Animals; Atrial Natriuretic Factor; Cyclic GMP; Endothelins; Humans; Metabolic Clearance Rate; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley

1993
Endogenous synthesis of endothelin-1 may mediate a delayed pressor response after injection of endothelin-1 in rats.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:2

    Topics: Alanine; Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Enalaprilat; Endothelin Receptor Antagonists; Endothelins; Fatty Acids, Unsaturated; Glycopeptides; Hydrazines; Injections, Intravenous; Male; Peptides, Cyclic; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane

1995
Pulmonary and renal neutral endopeptidase EC 3.4.24.11 in rats with experimental heart failure.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:6

    Topics: Alanine; Animals; Base Sequence; Heart Failure; Kidney; Lung; Male; Molecular Sequence Data; Neprilysin; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger

1995
Repression of angiotensin II and potentiation of bradykinin contribute to the synergistic effects of dual metalloprotease inhibition in heart failure.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:2

    Topics: Alanine; Angiotensin II; Animals; Biphenyl Compounds; Blood Pressure; Blood Volume; Bradykinin; Cricetinae; Drug Synergism; Enalaprilat; Heart Failure; Irbesartan; Male; Neprilysin; Tetrazoles; Vasodilation; Ventricular Function, Left

1995
Sodium loads enhance the natriuretic responses to atrial natriuretic peptide and neutral endopeptidase inhibitors in conscious cynomolgus monkeys.
    Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:11

    Topics: Administration, Oral; Alanine; Animals; Atrial Natriuretic Factor; Dose-Response Relationship, Drug; Endopeptidases; Female; Injections, Intravenous; Macaca fascicularis; Natriuretic Agents; Renal Circulation; Sodium, Dietary

1994
Potentiation of the renal responses to bradykinin by inhibition of neutral endopeptidase 3.4.24.11 and angiotensin-converting enzyme in anesthetized dogs.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:1

    Topics: Alanine; Anesthesia; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Cyclic GMP; Dogs; Drug Synergism; Female; Kidney; Male; Natriuresis; Neprilysin; Renal Circulation; Vascular Resistance; Vasodilation

1994
Inhibition of neutral endopeptidase 3.4.24.11 in conscious dogs with pacing induced heart failure.
    Cardiovascular research, 1993, Volume: 27, Issue:6

    Topics: Alanine; Animals; Atrial Natriuretic Factor; Cardiac Pacing, Artificial; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Female; Heart Failure; Hemodynamics; Kidney; Male; Natriuresis; Neprilysin; Protease Inhibitors; Urine

1993
Combined inhibition of neutral endopeptidase and angiotensin converting enzyme in cardiomyopathic hamsters with compensated heart failure.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:1

    Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiomyopathies; Cricetinae; Drug Synergism; Enalaprilat; Hemodynamics; Kidney; Male; Neprilysin

1993
Systemic hemodynamics, renal function and hormonal levels during inhibition of neutral endopeptidase 3.4.24.11 and angiotensin-converting enzyme in conscious dogs with pacing-induced heart failure.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:2

    Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Captopril; Cardiac Pacing, Artificial; Cyclic GMP; Dogs; Female; Heart Failure; Hemodynamics; Kidney; Male; Neprilysin; Renin

1993
Metabolism of endothelin-1 and big endothelin-1 by recombinant neutral endopeptidase EC.3.4.24.11.
    British journal of pharmacology, 1993, Volume: 109, Issue:4

    Topics: Alanine; Chromatography, High Pressure Liquid; DNA, Complementary; Endothelin-1; Endothelins; Glycopeptides; Humans; In Vitro Techniques; Iodine Radioisotopes; Neprilysin; Protein Precursors; Recombinant Proteins

1993
Hemodynamic effects of acute and chronic treatment with aladotril, a mixed inhibitor of neutral endopeptidase and angiotensin I-converting enzyme, in conscious rats with myocardial infarction.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:3

    Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Heart; Hemodynamics; Male; Myocardial Infarction; Neprilysin; Peptidyl-Dipeptidase A; Protease Inhibitors; Rats; Rats, Wistar

1995
Bradykinin B2 receptor-mediated chronotropic effect of bradykinin in isolated guinea pig atria.
    European journal of pharmacology, 1995, Jul-25, Volume: 281, Issue:1

    Topics: Adrenergic beta-Agonists; Alanine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Function; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Enzyme Inhibitors; Guinea Pigs; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Kallidin; Male; Myocardium; Nitric Oxide; Prostaglandins; Receptor, Bradykinin B2; Receptors, Bradykinin; Sensitivity and Specificity

1995
Determinants of in vivo activity of neutral endopeptidase 3.4.24.11 and angiotensin converting enzyme inhibitors.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:2

    Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Blood Pressure; Captopril; Female; Humans; Kidney; Macaca fascicularis; Neprilysin; Peptide Fragments

1996
Acute and chronic neutral endopeptidase inhibition in rats with aortocaval shunt.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:6

    Topics: Alanine; Angiotensin II; Animals; Aorta, Abdominal; Arteriovenous Shunt, Surgical; Atrial Natriuretic Factor; Cyclic GMP; Diuresis; Enzyme Inhibitors; Heart Failure; Hemodynamics; Male; Natriuresis; Neprilysin; Rats; Rats, Wistar; Renin; Vena Cava, Inferior

1996
Role of the neutral endopeptidase 24.11 in the conversion of big endothelins in guinea-pig lung parenchyma.
    British journal of pharmacology, 1996, Volume: 117, Issue:1

    Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Endothelin-1; Endothelins; Glycopeptides; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Neprilysin; Protease Inhibitors; Protein Precursors; Thiorphan

1996
Neutral endopeptidase inhibition, a new approach in the exploration of diabetic vasculopathy in rats.
    European journal of pharmacology, 1995, Oct-04, Volume: 285, Issue:1

    Topics: Alanine; Animals; Blood Pressure; Capillary Permeability; Captopril; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Female; Glycopeptides; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Streptozocin; Thiorphan

1995
Renal and depressor activity of C-natriuretic peptide in conscious monkeys: effects of enzyme inhibitors.
    Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:3

    Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cyclic GMP; Enzyme Inhibitors; Female; Kidney; Macaca fascicularis; Natriuretic Peptide, C-Type; Neprilysin; Proteins; Sodium

1996
Effect on prolonged inhibition of neutral endopeptidase on cardiac hypertrophy in rats with myocardial infarction.
    Cardiovascular drugs and therapy, 1996, Volume: 10, Issue:5

    Topics: Alanine; Animals; Atrial Natriuretic Factor; Cardiomegaly; Enzyme Inhibitors; Ligation; Male; Myocardial Infarction; Neprilysin; Rats; Rats, Wistar

1996
Acute and chronic neutral endopeptidase inhibition and the natriuretic response to acute volume expansion.
    European journal of pharmacology, 1998, Apr-24, Volume: 347, Issue:2-3

    Topics: Alanine; Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Cyclic GMP; Diuresis; Enzyme Inhibitors; Heart Rate; Hemodynamics; Kidney; Male; Natriuresis; Neprilysin; Rats; Rats, Wistar

1998
Renal effects of 2-mercaptoacetyl-L-leucyl-L-phenylalanine, a novel selective inhibitor of neutral endopeptidase 24.11 (Neprilysin): comparison with SQ 28,603.
    General pharmacology, 1999, Volume: 33, Issue:3

    Topics: Alanine; Animals; Blood Pressure; Cattle; Dipeptides; Enzyme Inhibitors; Kidney; Male; Neprilysin; Rats; Rats, Wistar; Regional Blood Flow; Renal Circulation; Sodium; Urodynamics; Vascular Resistance

1999