alanine has been researched along with sphingosine in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Medlock, KA; Merrill, AH | 1 |
| Merrill, AH; Sandhoff, K; van Echten, G; Wang, E | 1 |
| Handa, S; Ogura, M | 1 |
| Cook, WJ; McDonald, JM; Micoli, KJ; Pan, G; Williams, JP; Wu, Y | 1 |
| Kim, MS; Lee, DY; Schroeder, JJ; Wang, T | 1 |
| D'Andrea, RJ; Moretti, PA; Pitson, SM; Vadas, MA; Wattenberg, BW; Zebol, JR | 1 |
| Banerjee, R; Fisher, SK; Foster, DJ; Heacock, AM; Vitvitsky, VM | 1 |
| Dunn, TM; Gable, K; Gupta, SD; Han, G; Harmon, JM; Niranjanakumari, S | 1 |
| Bertea, M; Hersberger, M; Hornemann, T; Marti-Jaun, J; Othman, A; Rütti, MF; von Eckardstein, A | 1 |
| Brown, RH; Eichler, FS; Frosch, MP; Garofalo, K; Hornemann, T; Lee, HJ; Penno, A; Schmidt, BP; von Eckardstein, A | 1 |
| Abad, JL; Casas, J; Delgado, A; Fabriàs, G; Nieves, I; Rayo, P | 1 |
| Akagi, T; Esaki, K; Furuya, S; Hirabayashi, Y; Ogawa, T; Okamoto, M; Sayano, T; Sonoda, C; Suzuki, T; Yoshikawa, T | 1 |
| Duan, J; Merrill, AH | 1 |
| Abegg, D; Adibekian, A; Gentina, S; Gomez, L; Guex, N; Hannich, JT; Haribowo, AG; Martinou, JC; Ovize, M; Paillard, M; Pillot, B; Riezman, H; Thibault, H; Zumbuehl, A | 1 |
1 review(s) available for alanine and sphingosine
| Article | Year |
|---|---|
1-Deoxysphingolipids Encountered Exogenously and Made de Novo: Dangerous Mysteries inside an Enigma.
Topics: Alanine; Animals; Diabetes Mellitus; Humans; Lipids; Mutation; Non-alcoholic Fatty Liver Disease; Peripheral Nervous System Diseases; Serine C-Palmitoyltransferase; Sphingosine | 2015 |
1 trial(s) available for alanine and sphingosine
| Article | Year |
|---|---|
Oral L-serine supplementation reduces production of neurotoxic deoxysphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1.
Topics: Administration, Oral; Adult; Aged; Alanine; Animals; Depression, Chemical; Dose-Response Relationship, Drug; Female; Hereditary Sensory and Autonomic Neuropathies; Humans; Infertility, Male; Lipids; Male; Mice; Mice, Transgenic; Middle Aged; Mutation, Missense; Neurotoxins; Pain Perception; Pilot Projects; Point Mutation; Psychomotor Performance; Sciatic Nerve; Serine; Serine C-Palmitoyltransferase; Sphingolipids; Sphingosine; Stereoisomerism; Young Adult | 2011 |
12 other study(ies) available for alanine and sphingosine
| Article | Year |
|---|---|
Inhibition of serine palmitoyltransferase in vitro and long-chain base biosynthesis in intact Chinese hamster ovary cells by beta-chloroalanine.
Topics: Acyltransferases; Alanine; Animals; beta-Alanine; Biological Transport, Active; Cells, Cultured; Cricetinae; Female; In Vitro Techniques; Lipids; Microsomes, Liver; Rats; Serine; Serine C-Palmitoyltransferase; Sphingolipids; Sphingosine | 1988 |
Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ.
Topics: Acyltransferases; Alanine; Amidohydrolases; Animals; Carcinogens, Environmental; Cells, Cultured; Ceramidases; Cerebellum; Fumonisins; Galactose; Kinetics; Mice; Mycotoxins; Neurons; Serine C-Palmitoyltransferase; Sphingolipids; Sphingosine; Sphingosine N-Acyltransferase | 1993 |
Induction of apoptosis by novel synthesized acylamides of human lymphocytes.
Topics: Alanine; Amides; Antibodies; Apoptosis; Caspase 3; Caspase Inhibitors; Cell Survival; DNA Fragmentation; Enzyme Inhibitors; Humans; Intracellular Membranes; Jurkat Cells; Lymphocytes; Membrane Potentials; Myristic Acids; Sphingosine; Structure-Activity Relationship | 2000 |
Requirement of calmodulin binding by HIV-1 gp160 for enhanced FAS-mediated apoptosis.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Apoptosis; Binding Sites; Calmodulin; Caspase 3; Caspases; Enzyme Activation; fas Receptor; HIV Envelope Protein gp160; HIV-1; Humans; Jurkat Cells; Models, Molecular; Molecular Sequence Data; Myosin-Light-Chain Kinase; Peptide Fragments; Point Mutation; Protein Structure, Secondary; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Sphingosine; Transfection; Tryptophan | 2000 |
Fumonisin B(1) induces apoptosis in LLC-PK(1) renal epithelial cells via a sphinganine- and calmodulin-dependent pathway.
Topics: Alanine; Animals; Antimetabolites; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Calmodulin; Carboxylic Acids; Cyclin D1; Densitometry; Epithelial Cells; Flow Cytometry; Fumonisins; Kidney; LLC-PK1 Cells; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingosine; Swine | 2001 |
A point mutant of human sphingosine kinase 1 with increased catalytic activity.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Conserved Sequence; Enzyme Activation; Enzyme Stability; Glycine; Humans; Mutagenesis, Site-Directed; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Protein Folding; Sphingosine | 2001 |
Muscarinic receptor regulation of osmosensitive taurine transport in human SH-SY5Y neuroblastoma cells.
Topics: Alanine; Antioxidants; Biological Transport; Calcium; Cell Line, Tumor; Cyclopentanes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidine; Humans; Indans; Lysophospholipids; Muscarinic Agonists; Neuroblastoma; Osmolar Concentration; Oxotremorine; Receptors, Muscarinic; Saline Solution, Hypertonic; Sphingosine; Taurine; Thapsigargin; Thrombin; Tritium | 2009 |
A disease-causing mutation in the active site of serine palmitoyltransferase causes catalytic promiscuity.
Topics: Alanine; Animals; Biocatalysis; Catalytic Domain; CHO Cells; Cricetinae; Cricetulus; Extracellular Space; Hereditary Sensory and Autonomic Neuropathies; Humans; Isoenzymes; Kinetics; Mice; Mutation; Protein Multimerization; Protein Structure, Quaternary; Serine; Serine C-Palmitoyltransferase; Sphingosine; Substrate Specificity | 2010 |
Deoxysphingoid bases as plasma markers in diabetes mellitus.
Topics: Aged; Alanine; Biomarkers; Body Mass Index; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease Progression; Female; Humans; Lipoproteins; Male; Middle Aged; Serine; Sphingolipids; Sphingosine; Statistics as Topic | 2010 |
Straightforward access to spisulosine and 4,5-dehydrospisulosine stereoisomers: probes for profiling ceramide synthase activities in intact cells.
Topics: Acylation; Alanine; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Ceramides; Dose-Response Relationship, Drug; Fumonisins; Humans; Kinetics; Lipids; Organometallic Compounds; Oxidoreductases; Sphingosine; Stereoisomerism | 2013 |
L-Serine Deficiency Elicits Intracellular Accumulation of Cytotoxic Deoxysphingolipids and Lipid Body Formation.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Animals; Brain; Cells, Cultured; Female; Gene Knockout Techniques; Lipid Droplets; Lipids; Mice; Phosphoglycerate Dehydrogenase; Serine; Sphingolipids; Sphingosine | 2015 |
1-Deoxydihydroceramide causes anoxic death by impairing chaperonin-mediated protein folding.
Topics: Alanine; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Cell Division; Chaperonins; Feeding Behavior; Hypoxia; Ion Channels; Mice; Mice, Inbred C57BL; Mutation; Myocardial Reperfusion Injury; Protein Folding; Saccharomyces cerevisiae; Serine; Sphingosine | 2019 |