alanine has been researched along with serine in 1864 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 830 (44.53) | 18.7374 |
| 1990's | 323 (17.33) | 18.2507 |
| 2000's | 475 (25.48) | 29.6817 |
| 2010's | 178 (9.55) | 24.3611 |
| 2020's | 58 (3.11) | 2.80 |
| Authors | Studies |
|---|---|
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Brandsch, M; Gebauer, S; Laug, L; Schäfer, S; Thondorf, I; Voigt, V; Zebisch, K | 1 |
| Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S | 1 |
| Hikichi, M; Iida, S | 1 |
| Hara, TJ | 1 |
| Finley, JW; Friedman, M; Yeh, LS | 1 |
| Corrochano, G; DeFeudis, FV; Orensanz Munoz, LM; Sanchez del Alamo, MS; Vidal, MA | 1 |
| McGivan, JD | 1 |
| de Kantor, IN; Escoto, ML | 1 |
| Kieras, FJ | 1 |
| Becker, EL; Corcoran, BA; Schiffmann, E; Showell, HV; Smith, E; Ward, PA | 1 |
| Colosi, NW; Harper, AE; Tews, JK | 1 |
| Bradford, HF; Osborne, RH | 2 |
| Ferriero, D; Marogolis, FL | 1 |
| Scraba, DG; Ziola, BR | 1 |
| Edminson, PD; Kvamme, E; Reichelt, KL | 1 |
| Ponnamperuma, C; Sweeney, MA; Toste, AP | 1 |
| Ashman, PU; Newport, GR; Page, CR; Seed, JR; Stibbs, HH | 1 |
| Csonka, LN | 1 |
| Hartman, PE; Roth, DJ; Winkler, ME | 1 |
| Brown, A; Pope, WT; Reeves, RH | 1 |
| Walsh, C; Wang, E | 1 |
| Kamoun, P; Parvy, P | 1 |
| Dingwall, C; Fersht, AR | 1 |
| Baldacci, G; Falcone, C; Francisci, S; Frontali, L; Palleschi, C | 1 |
| Albani, M; Ishikura, H; Kersten, H; Murao, K | 1 |
| Alexandrov, S; Mepham, TB; Peters, AR | 1 |
| Sepulveda, FV; Smith, MW | 1 |
| Paterson, JY; Sepúlveda, FV; Smith, MW | 2 |
| Schuette, B; Vistica, DT | 1 |
| Biondi, A; Biondi, G; Gallone, U; Padula, P; Pignero, A; Quagliuolo, L | 1 |
| Christensen, HN; Handlogten, ME | 1 |
| Bürger, U | 1 |
| Davidson, CS; Fernstrom, JD; Hammarstrom-Wiklund, B; Munro, HN; Rand, WM; Wurtman, RJ | 1 |
| Kato, K; Kinoshita, F; Kotani, S; Morisaki, I; Watanabe, Y | 1 |
| Manavalan, P; Ponnuswamy, PK; Srinivasan, AR | 1 |
| Downs, F; Murty, VL; Peterson, C; Pigman, W | 1 |
| Borghetti, AF; Guidotti, GG; Tramacere, M | 1 |
| Bailey, RS; Fried, B | 1 |
| Sugimoto, E | 1 |
| Ablov, AV; Chapurina, LF; D'iakon, IA; Kaĭriak, LN | 1 |
| Elson, C; Shahidsaless, FM; Shrago, E; Spenneta, T | 1 |
| Cuénod, M; Henke, H | 1 |
| Brawand, F; Dieterle, P; Moser, UK; Walter, P | 1 |
| Ikenaka, T; Odani, S | 1 |
| Iliffe, TM; McAdoo, DJ; Novak, RA; Price, CH | 1 |
| Jontofsohn, R; Katz, N; Kluthe, R; Trivisas, G | 1 |
| Bradford, NM; Joseph, SK; McGivan, JD | 1 |
| Edmondson, JW; Li, TK; Lumeng, L | 1 |
| Anderman, F; Sacks, C; Sherwin, AL; Van Gelder, NM | 1 |
| Holt, RL | 1 |
| Liappis, N | 1 |
| Anda, LP; Dotchev, D; Liappis, N | 1 |
| Deutsch, HF; Fett, JW | 1 |
| Hammes, WP; Kandler, O; Schleifer, KH; Trippen, B | 1 |
| Cook, PF; Wedding, RT | 1 |
| Ho, CK; Kern, HL; Ostrove, SA | 1 |
| Adelberg, EA; Finkelstein, MC | 1 |
| Parente, A; Rinaldi, AM | 1 |
| Gautier, M; Lemonnier, A; Lemonnier, F; Moatti, N | 1 |
| Coufalik, A; Monder, C | 1 |
| Cain, GD; Nollen, PM; Prechel, DP | 1 |
| Chavancy, G; Fournier, A; Garel, JP | 1 |
| Davis, L; Kapke, G | 1 |
| Austen, KF; Boswell, RN; Goetzl, EJ | 1 |
| Barbeau, A; Beroniade, V; Breton, G; Geoffroy, G; Lemieux, B; Melançon, S; Shapcott, D | 1 |
| Lowe, NR; Robinson, C; Weatherell, JA | 1 |
| Hayes, ML; Hyatt, AT | 1 |
| Barker, JL; Nicoll, RA; Padjen, A | 1 |
| Lee, M; Oxender, DL; Robbins, JC | 1 |
| Fittler, F; Lossow, C; Wübbeler, W; Zachau, HG | 1 |
| Chavancy, G; Daillie, J; Garel, JP | 1 |
| Koizumi, K; Mayama, M; Sakazaki, R; Shoji, J; Wakisaka, Y | 1 |
| Hodges, RS; Merrifield, RB | 1 |
| Baxter, CF; Shank, RP | 1 |
| Black, JA; Harkins, RN; Stenzel, P | 1 |
| Baños, G; Daniel, PM; Moorhouse, SR; Pratt, OE | 2 |
| Rando, RR | 1 |
| Crisp, DM; Halestrap, AP; Mendes-Mourāo, J; Pogson, CI | 1 |
| Chellemi, F | 1 |
| Beart, PM; Minchin, MC | 1 |
| Harper, AE; Lutz, J; Tews, JK | 1 |
| Girard, JR; Guillet, I; Marliss, EB; Marty, J | 1 |
| Balikcioglu, S; Behnken, L; Besser, H; Förster, FJ; Grosshans, E; Neufahrt, A; Nowicki, L | 1 |
| Baetz, AL; Graham, CK; Hubbert, WT | 1 |
| Gundalakh, AI; Mel'k, MV; Shcheglova, SA; Volkova, ZA | 1 |
| Fein, JE; MacLeod, RA | 1 |
| Fendler, JH; Nagyvary, J; Nome, F | 1 |
| Jörnvall, H | 1 |
| Erfle, JD; Mahadevan, S; Sauer, FD | 1 |
| Guadalix, FJ; Ruiz, MC | 1 |
| Kester, AS; Mayfield, DC | 1 |
| Potts, JT; Tregear, GW | 1 |
| Benassi, CA; Guggi, A; Rocchi, R; Salvadori, S; Tomatis, R | 1 |
| Ibsen, KH; Marles, SW | 1 |
| Garel, J | 1 |
| Heinrich, D; Kubli, F; Metz, J; Wesch, H | 1 |
| Claybrook, DL | 1 |
| Jaenicke, R; Risse, B; Rudolph, R; Schumacher, G; Stempfer, G | 1 |
| Cox, BA; Henningsen, RA; Neve, KA; Neve, RL; Spanoyannis, A | 1 |
| Akasaka, T; Ono, N; Sawai, T; Yamaguchi, A | 1 |
| Christophe, J; De Neef, P; Gourlet, P; Robberecht, P; Vandermeers, A; Vandermeers-Piret, MC; Woussen-Colle, MC | 1 |
| Boutron, A; Goenner, S; Lemonnier, A; Moatti, N; Soni, T | 1 |
| Akino, T; Konno, R; Nagata, Y; Shimojo, T; Yamamoto, K; Yasumura, Y | 1 |
| Faden, AI | 1 |
| Countaway, JL; Davis, RJ; Nair, N; Robinson, HL; Taglienti-Sian, C; Theroux, SJ | 1 |
| Denu, JM; Fitzpatrick, PF | 3 |
| Kus, L; McNulty, JA; Ottersen, OP | 1 |
| Fersht, AR; Hirshberg, M; Sancho, J; Serrano, L | 1 |
| Akino, T; Masui, R; Nagata, Y | 1 |
| Alesiani, M; Davolio, P; Lombardi, G; Moroni, F; Pellicciari, R; Russi, P | 1 |
| Chua, NH; Furuya, M; Halfter, U; Kay, S; Nagatani, A; Stockhaus, J | 1 |
| Nagata, Y; Shimojo, T; Yamamoto, K | 1 |
| Lee, GJ; McFadden, BA | 1 |
| Brzović, PS; Dunn, MF; Ngo, K | 1 |
| Eijsink, VG; Van den Burg, B; Van der Zee, JR; Venema, G; Vriend, G | 1 |
| Bradford, HF; Croucher, MJ | 1 |
| Bradley, TM; Lo, YH; Rhoads, DE | 1 |
| Dantzler, WH; Silbernagl, S | 1 |
| Chain, D; Korc-Grodzicki, B; Kreizman, T; Shaltiel, S | 1 |
| Altenhofen, W; Bönigk, W; Eismann, E; Kaupp, UB; Kraus, W; Ludwig, J | 1 |
| Andersson, M; Bergenhem, N; Carlsson, U; Jonsson, BH; Kihlgren, A; Mårtensson, LG | 1 |
| Diner, BA; Nixon, PJ | 1 |
| Keck, W; Mottl, H; van der Linden, MP | 1 |
| Han, HP; Ido, E; Kezdy, FJ; Tang, J | 1 |
| Berendsen, HJ; Eijsink, VG; van den Burg, B; van der Zee, JR; Venema, G; Vriend, G | 1 |
| Fillingame, RH; Fraga, D; Oldenburg, M | 1 |
| Baker, K; Emfinger, SM; Fowlkes, DM; Lentz, BR; Pei, G | 1 |
| Bjoern, S; Christensen, M; Foster, DC; Kisiel, W; Komiyama, Y; Pedersen, AH; Thim, L; Wiberg, FC | 1 |
| Arbus, GS; Goldberg, DM; Ish-Shalom, N; Macpherson, NA; Moscarello, MA | 1 |
| Carrell, RW; Daly, M; Harper, PL; Perry, DJ; Price, J; Tait, RC; Walker, ID | 1 |
| Fujita, S; Mawhinney, TP; Peterson, EL; Schweitzer, VG; Woodson, BT | 1 |
| Amioka, H; Dojo, S; Hayashi, K; Hiraoka, M; Hirata, Y; Kurushima, H; Nakashima, K; Nishio, E; Ohtani, H; Saeki, M | 1 |
| Aguirre, J; Arteman, P; Brandariz, S; del Castillo, E; Silberstein, C; Uranga, J | 1 |
| Barbato, G; Bax, A; Ikura, M; Kay, LE; Krinks, M; Spera, S | 1 |
| Collen, D; Lijnen, HR; Nelles, L; Van Hoef, B | 1 |
| Brosnan, JT; Brosnan, ME; Dhanakoti, SN; Herzberg, GR | 1 |
| Collen, D; Declerck, PJ; Haber, E; Homcy, CJ; Quertermous, T; Russell, ME | 1 |
| Joshi-Barve, S; Rhoads, RE; Rychlik, W | 1 |
| Snell, EE; van Poelje, PD | 1 |
| LeMaster, DM; Markley, JL; Wang, JF | 1 |
| Dobbins, DE; Premen, AJ | 1 |
| Breitfeld, PP; Casanova, JE; Mostov, KE; Ross, SA | 1 |
| Merutka, G; Stellwagen, E | 1 |
| Sakharova, IS; Torchinsky, YM; Zakomirdina, LN | 1 |
| Fischer, Y; Kammermeier, H; Rose, H | 1 |
| Hakvoort, TB; Margoliash, E; Sprinkle, JR | 1 |
| Bourdel, G; Forestier, M; Gouhot, B | 1 |
| Hugenholtz, J; Ljungdahl, LG | 1 |
| Feher, G; McPherson, PH; Okamura, MY; Paddock, ML | 1 |
| DeWitt, DL; Kraemer, SA; Meade, EA; Shimokawa, T; Smith, WL | 1 |
| Furois-Corbin, S; Pullman, A | 1 |
| Cox, GB; Gibson, F; Howitt, SM | 1 |
| Bathurst, I; Matheson, N; Travis, J | 1 |
| Premen, AJ | 1 |
| Hundal, HS; Rennie, MJ; Watt, PW | 1 |
| Hascall, VC; Kimura, JH; Lohmander, LS; Shinomura, T | 1 |
| Horiuchi, T; Imai, M; Ishimura, Y; Koga, H; Makino, R; Matsushima-Hibiya, Y; Shimada, H; Watanabe, Y | 1 |
| Beale, D; Coadwell, J | 1 |
| Cheek, JM; Edmond, J; Jones, MR; Tamaki, J; Wu, PY | 1 |
| hupkin, DI; Murina, MA; Sergienko, VI | 1 |
| Benson, MD; Wallace, MR | 1 |
| Daly, MP; Demediuk, P; Faden, AI | 1 |
| Gottesman, MM; Kakehi, Y; Kioka, N; Komano, T; Pastan, I; Tsubota, J; Ueda, K | 1 |
| Ahl, PL; Khorana, HG; Mogi, T; Rothschild, KJ; Stern, LJ | 1 |
| Askanazi, J; Elwyn, DH; Gil, KM; Gump, FE; Kinney, JM; Starker, PM | 1 |
| Kimura, K; Kobayashi, H; Matsuoka, K | 1 |
| Allen, IC; Grieve, A; Griffiths, R | 1 |
| Mora, F; Peinado, JM | 1 |
| Horecker, BL; Panneerselvam, C; Wellner, D | 1 |
| Berk, AJ; Gaynor, RB; Ponticelli, A; Tsukamoto, AS | 1 |
| Arme, C; Jeffs, SA | 1 |
| Albajar, M; Hems, R; Klim, RA; Williamson, DH | 1 |
| Mann, GE; Peran, S | 1 |
| Crompton, DW; Ward, PF | 1 |
| Christensen, HN; Flickinger, KS; Pisoni, RL; Thoene, JG | 1 |
| de Jong, S; Driessen, AJ; Kodde, J; Konings, WN | 1 |
| Abdelrahman, F; Baklouti, F; Delaunay, J; el-Kabsh, M; Elwan, S | 1 |
| Southorn, BG; Thompson, JR | 1 |
| Bannai, S; Ishii, T; Sato, H; Watanabe, H | 1 |
| Bourre, JM; Lefauconnier, JM; Roux, F; Tayarani, I | 1 |
| Kopple, JD; Wolfson, M | 1 |
| Kleinhofs, A; Owais, WM | 1 |
| Jones, WM; Manning, JM | 1 |
| Hama, H; Shimamoto, T; Tsuchiya, T; Tsuda, M | 1 |
| Flückiger, R; Gallop, PM; Woodtli, T | 1 |
| Driessen, AJ; Konings, WN; Russell, JB; Strobel, HJ | 1 |
| Baklouti, F; Baudin-Chich, V; Delaunay, J; Kister, J; Marden, M; Poyart, C; Teyssier, G; Wajcman, H | 1 |
| Medlock, KA; Merrill, AH | 1 |
| Frasier-Scott, K; Hatzakis, H; Jones, CM; Seong, D; Wu, KK | 1 |
| Armstrong, CA; Granger, GA; Klostergaard, J | 1 |
| Consevage, MW; Phillips, AT | 1 |
| Hobbs, JG; Kaye, PL | 1 |
| Lund, P; Williamson, DH | 1 |
| Christensen, HN; Vadgama, JV | 1 |
| Mircevová, L; Mokrý, Z; Simonová, A | 1 |
| Longbottom, JL; Pepys, J | 1 |
| Kelly, B; Levy, JG | 1 |
| Bosma, M; Davis, G | 2 |
| Bryce, GF | 1 |
| Asghar, SS; Harold, FM; Levin, E | 1 |
| Abeles, RH; Krodel, E; Massey, V; Walsh, CT | 1 |
| Bizri, H; Hajjar, JJ; Khuri, RN | 1 |
| Aprison, MH; Daly, E; McBride, WJ | 1 |
| Hardy, MJ | 1 |
| Bhatnagar, L; Gupta, KG; Singh, B | 1 |
| Heilmann, HD | 1 |
| Colley, L; Fox, FR; Huggins, AK | 1 |
| Kasarian, BA | 1 |
| Bhatnager, L; Gupta, KG; Singh, B | 1 |
| Jaton, JC | 1 |
| Bassett, EW; Beiser, SM; Tanenbaum, SW | 1 |
| Pliskowá, M | 1 |
| Givol, D; Rüde, E | 1 |
| Bundgaard, L; Winther, A | 1 |
| Grula, EA; King, RD | 2 |
| Mikhail, MM; Patwardhan, VN; Waslien, CI | 1 |
| Murray, CL; Rabinowitz, JC; Samuel, CE | 1 |
| Heitmann, RN; Hoover, WH; Sniffen, CJ | 1 |
| Qadri, SM; Williams, RP | 1 |
| Chaloupka, J; Krecková, P | 1 |
| Banerjee, AB; Bhattacharyya, SK | 1 |
| Oppenheim, B; Patchornik, A | 1 |
| Clark, VL; Young, FE | 1 |
| Hubert, JC; Wurtz, B | 1 |
| Schmid, A | 2 |
| Braun, W; Weiss, C; Zschaler, W | 1 |
| Plapp, R; Strominger, JL | 2 |
| Veerkamp, JH | 1 |
| Davidson, EA; Hranisavljevic, J; Simpson, DL | 1 |
| Tatum, EL; Wrathall, CR | 1 |
| Vatin, AI | 1 |
| Yoshida, A | 1 |
| Herbert, E; Smith, CJ | 1 |
| Baranova, AM; Bragina, MP; Moroz, AF | 1 |
| Johnston, GA | 1 |
| Culp, WJ; Hardesty, B; Mosteller, RD | 1 |
| Abrol, YP; Blumenthal, SG; Conn, EE; Hendrickson, HR | 1 |
| Cheung, GP; Cotropia, JP; Sallach, HJ | 1 |
| Curtis, DR; De Groat, WC; Johnston, GA | 1 |
| Froncish, W; Kalmanson, AE; Kharitonenkov, IG; Yuferov, VP | 1 |
| Gross, J; Kang, AH | 1 |
| Bańkowski, E; Galasiński, W | 1 |
| Kung, HF; Wagner, C | 1 |
| Azizova, OA; Kaiushin, LP; Pulatova, MK | 1 |
| Crofford, OB; Lacy, WW; Minemura, T | 1 |
| De Groot, N; Lapidot, Y; Ziv, E | 1 |
| Bron, T; Rous, S | 1 |
| Harris, B; Osmond, CB | 1 |
| Asano, Y; Fukui, A; Sinoara, H | 1 |
| Fine, R; Harrington, MR; Murakami, WT; Sassan, ZB | 1 |
| Whiting, AH | 1 |
| Ogur, M; Ulane, R | 1 |
| Beck, JP; Befort, N; Ebel, JP; Mercier, J | 1 |
| Egelrud, T; Fielding, CJ; Fielding, PE; Havel, RJ; Olivecrona, T; Shore, VG | 1 |
| Schmidt, LS; Sojka, GA | 1 |
| Derevitskaya, VA; Kochetkov, NK; Likhosherstov, LM; Medvedev, SA | 1 |
| Keen, P; Roberts, PJ | 1 |
| Crippa, PR; Tedeschi, RA; Vecli, A | 1 |
| Eder, HA; Reese, H; Swaney, JB | 1 |
| Miyajima, R; Otsuka, S; Shiio, I | 1 |
| De Marchi, WJ; Johnston, GA | 1 |
| Santarius, KA; Stocking, CR | 1 |
| Black, CC; Lee, SS; Travis, J | 1 |
| Reizin, FN; Zeitlyonok, NA | 1 |
| Abeles, RH; Schonbrunn, A; Walsh, CT | 1 |
| Neuhaus, FC; Reusch, VM | 1 |
| Milman, G; Tiemeier, DC | 1 |
| Read, CP; Southworth, GC | 1 |
| Lewis, GP; McMartin, C; Rosenthal, SR; Yates, C | 1 |
| Leu, FY; Meister, A; Tate, SS | 1 |
| Yamamoto, M; Young, JL | 1 |
| Aktin, E; Bergisadi, N; Güven, KC; Koyuncuoglu, H | 1 |
| Kornecki-Gerrity, EH; Penney, DG | 1 |
| Nandedkar, AK | 1 |
| Brown, PC; Cowell, RD; Glynn, LE; Jones, JH | 1 |
| Konovessi-Panayotatos, A; Schultz, RM; Treadway, WJ | 1 |
| Allsopp, MN; Hullin, RP; Rees, JR | 1 |
| Asafov, GB; Ekisenina, NI; Ivanova, LM; Lumel'skiĭ, VIa; Smagin, VG | 1 |
| Lifshitz, F; Wapnir, RA | 1 |
| Carpe, AI; Smith, IK | 1 |
| Maier, R; Riniker, B; Rittel, W | 1 |
| Dancis, J; Schneider, H | 1 |
| Hass, LF; Jarboe, CJ; Noll, BW | 2 |
| Jäkel, A; Liappis, N | 1 |
| Crossley, AC; Evans, PD | 1 |
| Andrews, AT | 1 |
| el-Sewefy, AZ; Hegazi, SM | 1 |
| Anandaraj, MP; Cherayil, JD | 2 |
| Morino, Y; Okamoto, M; Osman, AM | 1 |
| Arai, T; Ichishima, E | 1 |
| Davis, SR; Mepham, TB | 1 |
| Friedmann, N; Miller, SL; Ring, D; Wolman, Y | 1 |
| Cheung, YS; Nobel, PS | 1 |
| Höcker, P; Stacher, A; Weiser, M | 1 |
| Iversen, LL; Snodgrass, SR | 1 |
| Kubacz, GJ | 1 |
| Lipsett, MN | 1 |
| Golini, F; Thach, RE | 1 |
| Bosma, G; Bosma, M; Davis, G | 1 |
| Fittler, F; Kruppa, J; Zachau, HG | 1 |
| Lessard, JL; Pestka, S | 1 |
| Geiger, R; König, W; Sandow, J; Wissmann, H | 1 |
| Barash, H; Druck, K; Halpern, YS | 1 |
| Brown, JL | 1 |
| Cosloy, SD | 1 |
| Miller, EJ | 1 |
| Sunde, ML | 1 |
| Oxender, DL; Robbins, JC | 1 |
| Claus, DR; Oxender, DL; Rahmanian, M | 1 |
| Hayaishi, O; Inoue, K; Kurosawa, A; Shizuta, Y; Tanabe, T | 1 |
| Barrell, BG; Guthrie, C; McClain, WH | 1 |
| Buchs, S | 1 |
| Bossinger, J; Cooper, TG; Lawther, RP | 1 |
| Ishikawa, E | 1 |
| Doctor, BP; Sodd, MA | 1 |
| Halpern, YS | 1 |
| Edmunds, LN; Sulzman, FM | 1 |
| Courtois, A; Van Gelder, NM | 1 |
| Mavrides, C | 1 |
| Csendes, A; Grossman, MI | 1 |
| Flory, B; Krassner, SM | 2 |
| Albers, RJ; DeTar, DF; Gilmore, F | 1 |
| Alleyne, GA; Roobol, A | 1 |
| Coulson, RA; Herbert, JD | 1 |
| Maurer, W; Rabbani, B; Schultze, B | 1 |
| Aue, WA; Gehrke, CW; Kuo, K; Kvenvolden, KA; Ponnamperuma, C; Rash, JJ; Stalling, DL; Zumwalt, RW | 1 |
| Ali, A; Faesel, JH; Sarantakis, D; Stevenson, D; Weinstein, B | 1 |
| Araya, A; Goodman, M; Maita, T; Matsuda, G; Ota, H; Prychodko, W; Watanabe, B | 1 |
| Evered, DF | 2 |
| Alimov, IIu; Iur'eva, EA; Marchenko, ZM | 1 |
| Liao, LL; Richardson, KE | 1 |
| Ando, T; Suzuki, K | 2 |
| Aleksandrov, VIa; Tabidze, DD | 1 |
| Lundgren, D; Ogur, M | 1 |
| Harper, AE; Maruyama, K; Sunde, ML | 1 |
| John, RA; Tudball, N | 1 |
| Okano, T; Sato, Y | 1 |
| Bentyn, K; Choroszewska, A; Jaszczak, S | 1 |
| Van Campen, D | 1 |
| Blanck, TJ; Dunathan, HC; Hindenlang, DM; Kallen, RG; Ulevitch, RJ; Voet, JG | 1 |
| Meister, A; Palekar, AG; Tate, SS | 1 |
| Burnison, BK; Morita, RY | 1 |
| Hsueh, HW; Moskowitz, M | 1 |
| Gutman, AB; Yu, TF | 2 |
| Frohman, LA; Stachura, ME | 1 |
| Gruber, L; Harris, JE | 1 |
| Paolucci, AM; Pennetti, V; Spadoni, MA | 1 |
| Adibi, SA; Amin, PM; Modesto, TA; Morse, EL | 1 |
| Kawakami, M; Shimura, K | 1 |
| Franchi-Gazzola, R; Gazzola, GC; Guidotti, GG; Ronchi, P | 1 |
| Bartels, K; Huber, R; Kukla, D; Rühlmann, A; Schwager, P | 1 |
| Harrap, BS; Heidemann, ER; Schiele, HD | 1 |
| Bajaj, SP; Butkowski, RJ; Heldebrant, CM; Mann, KG | 1 |
| Lowenstein, LM; Mayers, AM; Toback, FG | 1 |
| Tulinsky, A; Vandlen, RL | 1 |
| Hill, LJ; Martin, WG | 1 |
| De Loecker, W; Stas, ML | 1 |
| Manchester, KL; Turner, LV | 1 |
| Oja, SS; Sarajas, HS | 1 |
| Ito, E; Mizuno, Y; Yaegashi, M | 1 |
| Herbert, JD | 1 |
| Fottrell, PF; Spellman, CM | 1 |
| Trayhurn, P; van Heyningen, R | 1 |
| Thomas, P; Tudball, N | 1 |
| Dewedar, A; Shimi, IR; Shoukry, S | 1 |
| Fox, M; Roberts, E; Wein, J; Weinstein, C | 1 |
| Forrest, HS; Smith, RL | 1 |
| Daillie, J; Fournier, A; Garel, JP | 1 |
| Golban-Moghadam, N; Rahbar, S; Saoodi, H | 1 |
| Cole, RD; Colom, J; Cozcolluela, C; Phelan, JJ; Subirana, JA | 1 |
| Gaitonde, MK; Nixey, RW; Sharman, IM | 1 |
| Bernstein, IA; Gray, RH; Sibrack, LA | 1 |
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| Alatrash, N; Armstrong, DW; Berthod, A; Du, S; MacDonnell, FM; Sung, YS; Wang, Y; Wey, M | 1 |
| Fernández-García, C; Foden, CS; Islam, S; Maugeri, L; Powner, MW; Sheppard, TD | 1 |
| Baek, SA; Cha, SI; Choi, JE; Choi, SH; Do Yoo, J; Do, SK; Hong, MJ; Kang, HG; Kim, CH; Kim, JH; Kim, S; Lee, J; Lee, JH; Lee, SY; Lee, WK; Lee, YH; Park, JY; Seo, H; Yoo, SS | 1 |
| Bai, P; Cheng, H; He, M; Ni, D; Ruan, L; Wang, L; Wei, K; Wu, L | 1 |
| Badepally, NG; Singh, A; Surolia, A | 1 |
| Chhin, D; Mauzeroll, J; Moussa, S; Pollegioni, L | 1 |
| Borghese, F; Cesaro, T; Hayashi, Y; Michiels, T; Vertommen, D; Wavreil, F | 1 |
| Huang, C; Liu, F; Ou, J; Ou, S; Yin, Z; Zheng, J; Zou, Z | 1 |
| Mauzeroll, J; Moussa, S; Murtas, G; Pollegioni, L | 1 |
| Furusho, A; Hamase, K; Ishii, C; Kamarulzaman, A; Kamaruzzaman, SB; Lee, CS; Leong, KH; Mita, M; Rajasuriar, R; Shaharudin, S; Yap, SH; Zulhaimi, NS | 1 |
| Li, Y; Ping, Q; Wang, S | 1 |
| Chen, H; Pan, H; Ren, F; Ren, P; Wang, W | 1 |
| Bak, K; Murshed, M; Parashar, A | 1 |
| Karakawa, S; Kawasaki, M; Mine, T; Nishitani, S; Sato, W; Shindo, D; Somekawa, S; Suzuki, K; Toyoda, S; Umeda, K | 1 |
| Jayanthi, LD; Mannangatti, P; Ragu Varman, D; Ramamoorthy, S; Subler, MA; Windle, JJ | 1 |
| Bangham, M; Betancor, G; Jeon, JK; Jimenez-Guardeño, JM; Lynham, S; Malim, MH; Shah, K | 1 |
| Li, R; Shi, W; Yan, Z; Yao, L | 1 |
| Egawa, D; Goto, A; Hanada, K; Kumagai, K; Shimasaki, K; Tomishige, N; Yamaji, T | 1 |
| Dong, M; Jin, W; Yuan, S; Zhang, H | 1 |
| Arthur, JSC; Bonnello, MVG; Cooper, DD; Frenguelli, BG; Morè, L; Perrett, P; Privitera, L | 1 |
| Cheng, J; Jiang, H; Xu, L | 1 |
| Chen, X; Ge, T; He, Z; Wang, J; Yuan, H; Zhang, L | 1 |
| Cheng, Y; Guo, Y; Jiang, W; Liu, C; Qian, H; Yang, F; Yao, W; Zhao, Y | 1 |
| Ates, O; Toker, EB; Yesilbag, K | 1 |
| Cordes, T; Gengatharan, J; Khare, SV; Kuna, RS; McGregor, GH; Metallo, CM; Muthusamy, T | 1 |
| Gao, Y; Li, L; Li, Y; Xiu, M | 1 |
| Chen, L; Gu, J; Huang, C; Kong, Q; Lin, D; Lu, R; Wu, W | 1 |
| Kim, MJ; Kim, YS; Mi Lee, S; Moon, B; Park, HH | 1 |
| Ding, T; Gao, L; Ge, J; Gu, Q; Ma, X; Shen, W; Wang, H; Xue, F; Zhang, X | 1 |
| Ji, G; Luo, B; Shen, G; Tian, T | 1 |
| Cui, Y; Feng, C; Gao, H; Li, D; Mao, H; Wang, C; Wei, X; Yang, J; Zhu, J | 1 |
| Deng, W; He, F; Nie, Y; Wang, R; Xu, J; Yan, R; Yang, Z; Yu, L; Zhang, Y | 1 |
| Binder, U; Friedrich, L; Kikuchi, Y; Matsuda, Y; Skerra, A | 1 |
| Ahmad, H; Ahmad, N; Chen, M; Du, J; Jin, Y; Khan, A; Li, X; Ouyang, Y; Tian, Z; Yang, P; Yang, Z; Zeng, L; Zhao, X; Zheng, X | 1 |
| Endo, K; Kitamura, H; Makabe, H; Sawa, T; Tanaka, S; Umezawa, K | 1 |
| An, J; Jia, X; Li, X; Liu, R; Liu, S; Mo, Y; Wei, X; Zhang, S; Zhang, Y; Zhou, L | 1 |
| Kuczera, K; Lee, KH | 1 |
| Huang, CC; Lane, HY; Wei, IH; Yang, HT | 1 |
| Ban, Q; Hou, YY; Huang, T; Ma, B; Shi, L; Zhang, ML; Zhang, Q; Zhou, YF | 1 |
| Ansell, BRE; Bahlo, M; Bernstein, PS; Bonelli, R; Egan, C; Friedlander, M; Fruttiger, M; Gantner, ML; Green, CR; Handzlik, MK; Hart, B; McGregor, GH; Metallo, CM; Reilly, MM; Trombley, J; Tzaridis, S; Wallace, M | 1 |
| Chen, M; Chen, ZS; Deng, R; Huang, J; Huang, M; Liu, R; Lyu, W; Miao, Q; Qi, M; Qi, Q; Wang, C; Wen, Q; Wu, C; Xie, J; Ye, W; Zhang, D; Zhang, J; Zhang, Z | 1 |
| Hashemi, M; Moieni, A; Sabet, MS | 1 |
| Cai, Y; Deng, Z; Hao, H; Li, S; Shi, C; Song, J; Yang, Q; Zhuang, G | 1 |
| Liu, Y; Luo, T; Meng, X; Yu, G; Zhang, J; Zhang, R | 1 |
| Liao, Q; Wang, Z; Xie, P | 1 |
| Khalid, A; O'Brien-Simpson, NM; Pyreddy, S; Qazi, F; Redmond, CE; Shukla, R; Tomljenovic-Hanic, S; Verma, R | 1 |
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Kinoshita, H; Shimizu, K | 1 |
| Dean, KE; Klein, G; Renaudet, O; Reymond, JL | 1 |
25 review(s) available for alanine and serine
| Article | Year |
|---|---|
Genetic amyloidosis: recent advances.
Topics: Alanine; Amyloidosis; DNA Mutational Analysis; Humans; Methionine; Polymorphism, Restriction Fragment Length; Prealbumin; Serine; Tyrosine | 1989 |
Metabolic activation of the mutagen azide in biological systems.
Topics: Alanine; Azides; Biotransformation; DNA Damage; DNA Repair; Mutagenicity Tests; Mutagens; Plants; Salmonella typhimurium; Serine; Sodium Azide; Structure-Activity Relationship | 1988 |
Inter-tissue nitrogen fluxes.
Topics: Alanine; Amino Acids; Animals; Erythrocytes; Glutamine; Glycine; Humans; Intestine, Small; Liver; Muscles; Nitrogen; Rats; Serine; Wounds and Injuries | 1985 |
[Tissue collagenolytic enzymes].
Topics: Alanine; Animals; Anura; Biodegradation, Environmental; Collagen; Connective Tissue; Glycine; Humans; Hydroxyproline; Microbial Collagenase; Puromycin; Serine; Valine | 1970 |
A review of biochemical studies on the genetically distinct collagens of the skeletal system.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Bone and Bones; Cartilage, Articular; Collagen; Glutamates; Homoserine; Hydroxyproline; Leucine; Peptides; Phenylalanine; Proline; Rats; Serine; Threonine; Valine | 1973 |
Utilization of D- and DL- amino acids and analogs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Histidine; Isomerism; Keto Acids; Leucine; Methionine; Nutritional Requirements; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1972 |
[Dynamic states of amino acid metabolism in mammals (author's transl)].
Topics: Alanine; Amino Acids; Ammonia; Animals; Carbon Radioisotopes; Erythrocytes; Fasting; Glutamine; Glycine; Humans; Liver; Rats; Serine | 1974 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
[Structure of transfer RNA].
Topics: Alanine; Chemical Phenomena; Chemistry; Phenylalanine; RNA, Transfer; Serine; Tyrosine; Valine | 1967 |
[Multiplicity and specificity in code recognition of tRNA against specific amino acid].
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography; Cystine; Escherichia coli; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Leucine; Liver; Lysine; Phenylalanine; Rabbits; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Serine; Threonine; Tyrosine; Yeasts | 1969 |
Selective cleavage and modification of peptides and proteins.
Topics: Alanine; Aspartic Acid; Chemical Phenomena; Chemistry; Chymotrypsin; Cysteine; Glutamates; Glycine; Hydrogen-Ion Concentration; Methionine; Muramidase; Oxidation-Reduction; Peptides; Phenylalanine; Proline; Proteins; Pyrrolidines; Ribonucleases; Serine; Succinates; Threonine; Tryptophan | 1970 |
Transport of amino acids and peptides in the gut and the kidney.
Topics: Adult; Alanine; Amino Acids; Animals; Biological Transport, Active; Digestive System; Glycine; Hartnup Disease; Histidine; Humans; Hydrolysis; Intestinal Absorption; Kidney; Kidney Tubules; Leucine; Lysine; Methionine; Peptides; Phenylalanine; Proteins; Rats; Serine; Threonine; Tryptophan; Valine | 1971 |
Advances in amino acid metabolism in mammals.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acid Oxidoreductases; Amino Acids; Animals; Biological Transport; Dietary Proteins; Glutamates; Glycine; Humans; Liver; Mitochondria; Organ Specificity; Ornithine; Purine Nucleotides; Serine; Threonine; Transaminases | 1981 |
Distribution of free D-amino acids in tissues and body fluids of vertebrates.
Topics: Alanine; Animals; Aspartic Acid; Humans; Kidney Diseases; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism; Vertebrates | 1997 |
[Glycine therapy of schizophrenia; its rationale and a review of clinical trials].
Topics: Acetamides; Alanine; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Cycloserine; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Humans; Prodrugs; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine | 1998 |
[Biosynthesis of nonessential amino acids and the urea-cycle in silkworms].
Topics: Alanine; Ammonia; Animals; Bombyx; Fibroins; Glycine; Isotope Labeling; Magnetic Resonance Spectroscopy; Serine; Urea | 2001 |
ELAC2/HPC2 polymorphisms, prostate-specific antigen levels, and prostate cancer.
Topics: Aged; Alanine; Case-Control Studies; Genetic Predisposition to Disease; Heterozygote; Homozygote; Humans; Leucine; Linear Models; Logistic Models; Male; Middle Aged; Neoplasm Proteins; Odds Ratio; Polymorphism, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Research Design; Risk Assessment; Risk Factors; Serine; Threonine | 2003 |
Posttranslational modifications of Bcl2 family members--a potential therapeutic target for human malignancy.
Topics: Alanine; Animals; Apoptosis; bcl-X Protein; Cell Death; Cytoplasm; DNA, Complementary; Humans; Mice; Mice, Transgenic; Models, Biological; Mutation; Neoplasms; Phosphorylation; Protein Conformation; Protein Processing, Post-Translational; Protein Structure, Secondary; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Serine; Taxoids; Treatment Outcome | 2006 |
Potentiation of the NMDA receptor in the treatment of schizophrenia: focused on the glycine site.
Topics: Acetamides; Alanine; Antipsychotic Agents; Clozapine; Cognition; Cycloserine; Dopamine Agents; Drug Synergism; Drug Therapy, Combination; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Humans; Monoamine Oxidase Inhibitors; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia; Schizophrenic Psychology; Serine | 2008 |
Amyloid neuropathy with transthyretin mutations: overview and unique Ala97Ser in Taiwan.
Topics: Age of Onset; Alanine; Amyloid Neuropathies; Female; Genetic Predisposition to Disease; Humans; Male; Mutation; Prealbumin; Serine; Sex Factors; Taiwan | 2011 |
Insights into the evolution of lanthipeptide biosynthesis.
Topics: Alanine; Amino Acids; Bacterial Proteins; Cyclization; Cysteine; Evolution, Molecular; Hydro-Lyases; Multienzyme Complexes; Peptides, Cyclic; Protein Processing, Post-Translational; Serine; Sulfides; Threonine | 2013 |
Formylglycine, a post-translationally generated residue with unique catalytic capabilities and biotechnology applications.
Topics: Alanine; Animals; Binding Sites; Biotechnology; Catalysis; Catalytic Domain; Cysteine; Glycine; Humans; Models, Molecular; Protein Processing, Post-Translational; Serine; Sulfotransferases | 2015 |
Chiral separations for d-amino acid analysis in biological samples.
Topics: Alanine; Amino Acids; Animals; Body Fluids; Chromatography, High Pressure Liquid; D-Aspartic Acid; Electrophoresis, Capillary; Humans; Serine; Stereoisomerism; Tissue Distribution | 2016 |
PASylation as a Powerful Technology for Improving the Pharmacokinetic Properties of Biopharmaceuticals.
Topics: Alanine; Animals; Biological Products; Biopharmaceutics; Humans; Polyethylene Glycols; Proline; Radiopharmaceuticals; Serine; Treatment Outcome | 2018 |
An update regarding the role of WNK kinases in cancer.
Topics: Alanine; Animals; Bicarbonates; Mammals; Neoplasms; Neovascularization, Pathologic; Proline; Serine; Sodium Chloride Symporters; Threonine | 2022 |
7 trial(s) available for alanine and serine
| Article | Year |
|---|---|
[The significance of nonessential amino acids for the human nitrogen metabolism during parenteral feeding].
Topics: Adult; Aged; Alanine; Amino Acids; Citrulline; Cystine; Diet; Female; Glycine; Humans; Male; Middle Aged; Nitrogen; Parenteral Nutrition; Proline; Serine; Taurine; Tyrosine | 1968 |
Serum levels of excitatory amino acids, serine, glycine, histidine, threonine, taurine, alanine and arginine in treatment-resistant depression: modulation by treatment with antidepressants and prediction of clinical responsivity.
Topics: Adult; Aged; Alanine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arginine; Asparagine; Aspartic Acid; Depressive Disorder, Major; Drug Resistance; Drug Therapy, Combination; Excitatory Amino Acids; Female; Fluoxetine; Glycine; Histidine; Humans; Male; Middle Aged; Personality Inventory; Pindolol; Prognosis; Selective Serotonin Reuptake Inhibitors; Serine; Taurine; Threonine; Trazodone; Treatment Outcome | 1998 |
Thiopental and midazolam do not seem to impede metabolism of glutamate in brain-injured patients.
Topics: Adolescent; Adult; Aged; Alanine; Brain Injuries; Cerebral Ventricles; Glutamic Acid; Glutamine; Humans; Hypnotics and Sedatives; Lactates; Midazolam; Middle Aged; Serine; Thiopental | 1999 |
Multiple superoxide dismutase 1/splicing factor serine alanine 15 variants are associated with the development and progression of diabetic nephropathy: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications G
Topics: Alanine; Albuminuria; Amino Acid Substitution; Diabetic Nephropathies; Diabetic Retinopathy; Disease Progression; Genetic Variation; Genotype; Humans; Hypoglycemic Agents; Nuclear Proteins; Polymorphism, Single Nucleotide; RNA-Binding Proteins; Serine; Serine-Arginine Splicing Factors; Superoxide Dismutase; Superoxide Dismutase-1; Treatment Outcome | 2008 |
Oral L-serine supplementation reduces production of neurotoxic deoxysphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1.
Topics: Administration, Oral; Adult; Aged; Alanine; Animals; Depression, Chemical; Dose-Response Relationship, Drug; Female; Hereditary Sensory and Autonomic Neuropathies; Humans; Infertility, Male; Lipids; Male; Mice; Mice, Transgenic; Middle Aged; Mutation, Missense; Neurotoxins; Pain Perception; Pilot Projects; Point Mutation; Psychomotor Performance; Sciatic Nerve; Serine; Serine C-Palmitoyltransferase; Sphingolipids; Sphingosine; Stereoisomerism; Young Adult | 2011 |
A single administration of 'microbial' D-alanine to healthy volunteers augments reaction to negative emotions: A comparison with D-serine.
Topics: Administration, Oral; Adult; Affect; Alanine; Cognition; Double-Blind Method; Emotions; Facial Expression; Female; Humans; Hydrocortisone; Male; Memory; Mental Recall; Saliva; Serine; Young Adult | 2020 |
Effects of Five Amino Acids (Serine, Alanine, Glutamate, Aspartate, and Tyrosine) on Mental Health in Healthy Office Workers: A Randomized, Double-Blind, Placebo-Controlled Exploratory Trial.
Topics: Adult; Aged; Alanine; Amino Acids; Aspartic Acid; Double-Blind Method; Glutamic Acid; Humans; Mental Fatigue; Mental Health; Middle Aged; Occupational Health; Serine; Treatment Outcome; Tyrosine; Young Adult | 2022 |
1832 other study(ies) available for alanine and serine
| Article | Year |
|---|---|
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
Topics: Amino Acid Transport Systems; Caco-2 Cells; Endocytosis; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters | 2011 |
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2022 |
Effect of taurine on ethanol-induced sleeping time in mice.
Topics: Alanine; Aminobutyrates; Animals; Arginine; Cysteic Acid; Dose-Response Relationship, Drug; Ethanol; Glycine; Injections, Intraperitoneal; Isethionic Acid; Lysine; Male; Mice; Reaction Time; Serine; Sleep; Taurine | 1976 |
Effects of pH on the olfactory responses to amino acids in rainbow trout, Salmo gairdneri.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Electric Conductivity; Hydrogen-Ion Concentration; Methionine; Olfactory Bulb; Salmonidae; Serine; Smell; Trout | 1976 |
Reactions of proteins with dehydroalanines.
Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry; Cystine; Hydrogen-Ion Concentration; Lysine; Proteins; Serine; Temperature | 1977 |
Substrate-specificity of "high-affinity", Na+ -independent binding of beta-alanine to cerebral synaptosomal-mitochondrial fractions.
Topics: Alanine; Animals; beta-Alanine; Bicuculline; Binding, Competitive; Brain; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Leucine; Male; Mitochondria; Neurotransmitter Agents; Rats; Serine; Strychnine; Synaptosomes; Taurine; Valine | 1978 |
Mechanism of the stimulation of serine and alanine transport into isolated rat liver cells by bicarbonate ions.
Topics: Alanine; Animals; Bicarbonates; Biological Transport; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Liver; Male; Rats; Serine; Stimulation, Chemical | 1979 |
Nitrate reductase activity of Mycobacterium tuberculosis and Mycobacterium bovis in the presence of electron donors.
Topics: Acetates; Alanine; BCG Vaccine; Mycobacterium bovis; Mycobacterium tuberculosis; Nitrate Reductases; Polysorbates; Propionates; Pyruvates; Serine | 1978 |
Alkaline borohydride treatment of cartilage keratan sulfate: a comparison of two reaction conditions.
Topics: Alanine; Animals; Cattle; Chromatography, Ion Exchange; Evaluation Studies as Topic; Galactosamine; Glucosamine; Glycosaminoglycans; Keratan Sulfate; Methods; Nasal Septum; Papain; Serine; Threonine | 1975 |
The isolation and partial characterization of neutrophil chemotactic factors from Escherichia coli.
Topics: Acetylation; Alanine; Animals; Ascitic Fluid; Aspartic Acid; Bacterial Proteins; Bacteriological Techniques; Chemotaxis; Chromatography, Gel; Chromatography, Thin Layer; Complement C5; Dansyl Compounds; Electrophoresis, Polyacrylamide Gel; Enzymes; Escherichia coli; Glutamates; Glycine; Neutrophils; Peptides; Periodic Acid; Rabbits; Serine | 1975 |
Effect of amino acid meals on hepatic alpha-aminoisobutyrate transport and cyclic AMP.
Topics: Adrenalectomy; Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Asparagine; Biological Transport; Caseins; Cyclic AMP; Diet; Electrolytes; Gelatin; Glutamine; Glycine; Inulin; Liver; Male; Protein Hydrolysates; Rats; Serine; Sodium Glutamate; Stimulation, Chemical | 1975 |
The influence of sodium, potassium and lanthanum on amino acid release from spinal-medullary synaptosomes.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Depression, Chemical; Electric Stimulation; Female; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine; Hydroxymercuribenzoates; Lactates; Lanthanum; Medulla Oblongata; Ouabain; Potassium; Rats; Serine; Sodium; Spinal Cord; Stimulation, Chemical; Synaptic Transmission; Synaptosomes | 1975 |
Denervation in the primary olfactory pathway of mice. II. Effects on carnosine and other amine compounds.
Topics: Alanine; Animals; Aspartic Acid; Carnosine; Cerebellum; Dansyl Compounds; Denervation; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamates; Lysine; Male; Mice; Mice, Inbred Strains; Olfactory Bulb; Olfactory Mucosa; Rats; Serine; Species Specificity; Synaptic Transmission; Taurine | 1975 |
Structure of the Mengo virion. IV. Amino- and carboxyl-terminal analyses of the major capsid polypeptides.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aspartic Acid; Capsid; Glutamine; Glycine; Leucine; Mengovirus; Models, Biological; Peptides; Serine; Viral Proteins | 1976 |
The formation of peptido-amines from constituent amino acids and histamine in hypothalamic tissue.
Topics: Alanine; Amines; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Cyclic AMP; gamma-Aminobutyric Acid; Glutamine; Glycine; Haplorhini; Histamine; Hypothalamus; Mice; Peptide Biosynthesis; Serine; Swine | 1976 |
Formation of amino acids by cobalt-60 irradiation of hydrogen cyanide solutions.
Topics: Alanine; Amino Acids; Aspartic Acid; Cobalt Radioisotopes; Glutamates; Glycine; Hydrogen Cyanide; Hydrolysis; Serine; Threonine; Valine | 1976 |
Alteration of free serum amino acids in voles infected with Trypanosoma brucei gambiense.
Topics: Alanine; Amino Acids; Animals; Arvicolinae; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Male; Proline; Serine; Threonine; Trypanosomiasis, African; Tryptophan; Tyrosine; Valine | 1977 |
Use of 3H and 14C double-labeled glucose to assess in vivo pathways of amino acid biosynthesis in Escherichia coli.
Topics: Alanine; Amino Acids; Aspartic Acid; Carbon Radioisotopes; Escherichia coli; Glucose; Glutamates; Glycine; Glycolysis; Isoleucine; Leucine; Methionine; Radioactive Tracers; Serine; Tritium; Tyrosine; Valine | 1977 |
Promoter- and attenuator-related metabolic regulation of the Salmonella typhimurium histidine operon.
Topics: Alanine; Carnosine; Chromosome Mapping; Genes; Glucose; Guanosine Tetraphosphate; Histidine; Operon; Salmonella typhimurium; Serine | 1978 |
The identification of the tRNA substrates for the supK tRNA methylase.
Topics: Alanine; Anticodon; Hydrolysis; RNA, Bacterial; RNA, Transfer; Salmonella typhimurium; Serine; tRNA Methyltransferases; Uridine | 1978 |
Suicide substrates for the alanine racemase of Escherichia coli B.
Topics: Affinity Labels; Alanine; Alanine Racemase; Amino Acid Isomerases; Amino Acids; Escherichia coli; Isomerism; Kinetics; Serine; Structure-Activity Relationship; Substrate Specificity | 1978 |
[Effect of n-dipropyl-acetate on the elimination of urinary amino acids].
Topics: Alanine; Amino Acids; Child; Glutamates; Glutamine; Glycine; Histidine; Humans; Male; Ornithine; Serine; Valproic Acid | 1978 |
Cysteinyl-tRNA synthetase from Escherichia coli does not need an editing mechanism to reject serine and alanine. High binding energy of small groups in specific molecular interactions.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Cysteine; Escherichia coli; Kinetics; Protein Binding; Serine; Substrate Specificity | 1979 |
Mitochondrial protein-synthesizing machinery in Saccharomyces cerevisiae grown in different metabolic conditions. Variability of seryl-tRNA and alanyl-tRNA isoacceptor patterns.
Topics: Alanine; Fermentation; Fungal Proteins; Mitochondria; Nucleic Acid Hybridization; Oxygen Consumption; Protein Biosynthesis; RNA, Transfer; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae; Serine | 1979 |
On the biosynthesis of 5-methoxyuridine and uridine-5-oxyacetic acid in specific procaryotic transfer RNAs.
Topics: Alanine; Bacillus subtilis; Escherichia coli; Oligoribonucleotides; RNA, Transfer; S-Adenosylmethionine; Serine; Threonine; Uridine; Valine | 1978 |
Effects of increased supply of essential amino acids on the metabolism of the isolated perfused guinea-pig mammary gland.
Topics: Alanine; Amino Acids, Essential; Animals; Female; Guinea Pigs; In Vitro Techniques; Mammary Glands, Animal; Methionine; Milk Proteins; Perfusion; Serine; Tryptophan | 1979 |
Sodium dependence of neutral amino acid uptake into rabbit ileum.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Ileum; Intestinal Mucosa; Kinetics; Methionine; Rabbits; Serine; Sodium | 1979 |
Two-carrier influx of neutral amino acids into rabbit ileal mucosa.
Topics: Alanine; Animals; Biological Transport; Extracellular Space; Ileum; Intestinal Mucosa; Kinetics; Methionine; Microvilli; Models, Biological; Rabbits; Serine | 1979 |
Substrate specificity of a high-affinity, monovalent cation-dependent amino acid carrier.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Leucine; Leukemia L1210; Lithium; Mice; Potassium; Serine; Sodium; Substrate Specificity | 1979 |
[Free amino acids in calf embryos].
Topics: Alanine; Amino Acids; Animals; Cattle; Embryo, Mammalian; Glycine; Histidine; Isoleucine; Leucine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1979 |
Does the non-saturable cell entry apply to the charge-free form of amino acids?
Topics: Alanine; Amino Acids; Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Culture Techniques; Serine; Stereoisomerism | 1977 |
[Studies on the metabolism of parenterally infused amino acids in healthy adults].
Topics: Adult; Alanine; Amino Acids; Female; Glycine; Humans; Infusions, Parenteral; Male; Methionine; Serine; Sex Factors | 1977 |
Diurnal variations in plasma concentrations of tryptophan, tryosine, and other neutral amino acids: effect of dietary protein intake.
Topics: Adult; Alanine; Amino Acids; Circadian Rhythm; Dietary Proteins; Glycine; Humans; Isoleucine; Leucine; Male; Middle Aged; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1979 |
The effect of replacement of L-alanine residue by glycine, L-serine or D-alanine in an N-acetylmuramyl-L-alanyl-D-isoglutamine on immunoadjuvancies of molecules.
Topics: Adjuvants, Immunologic; Alanine; Animals; Antibody Formation; Chemical Phenomena; Chemistry; Cornea; Female; Glycine; Glycopeptides; Guinea Pigs; Hypersensitivity, Delayed; Immunoglobulin G; Ovalbumin; Serine; Stereoisomerism | 1977 |
Solvent accessibilities in glycyl, alanyl and seryl dipeptides.
Topics: Alanine; Chymotrypsin; Dipeptides; Glycine; Hydrogen Bonding; Models, Chemical; Muramidase; Protein Conformation; Serine; Solvents | 1977 |
Quantitation of the beta-elimination reaction as used on glycoproteins.
Topics: Alanine; Amino Acids; Borohydrides; Butyrates; Chemistry, Organic; Galactosamine; Glucosamine; Glycoproteins; Hexosamines; Organic Chemistry Phenomena; Serine; Serum Albumin; Threonine | 1977 |
Serum-mediated regulation of amino acid transport in cultured chick embryo fibroblasts.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport, Active; Blood; Cells, Cultured; Culture Media; DNA; Glycine; Kinetics; Proline; Serine | 1977 |
Thin layer chromatographic analyses of amino acids in Echinostoma revolutum (Trematoda) adults.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Chromatography, Thin Layer; Echinostoma; Isoleucine; Leucine; Methionine; Proline; Serine; Tyrosine; Valine | 1977 |
[Amino acid metabolism related to carbohydrate metabolism (author's transl)].
Topics: Alanine; Amino Acids; Animals; Carbohydrate Metabolism; Gluconeogenesis; Rats; Serine | 1977 |
[Electron diffraction study of crystals of a copper(II) complex with L-alpha-alanine and L-serine Cu(L-alan)(L-ser)].
Topics: Alanine; Chemical Phenomena; Chemistry; Copper; Serine | 1978 |
Glyceroneogenesis in rat and guinea pig adipose tissue during the fed and fasted states.
Topics: Adipose Tissue; Alanine; Animals; Eating; Fasting; Glycerides; Glycerol; Glycerophosphates; Guinea Pigs; Lactates; Pyruvates; Rats; Serine | 1978 |
Uptake of L-alanine, glycine and L-serine in the pigeon central nervous system.
Topics: Alanine; Animals; Biological Transport, Active; Cell Fractionation; Columbidae; Glycine; Hypotonic Solutions; Kinetics; Mitochondria; Potassium; Serine; Sodium; Spinal Cord; Superior Colliculi; Telencephalon; Temperature | 1978 |
Alanine metabolism in rat liver mitochondria.
Topics: Alanine; Alanine Transaminase; Animals; Arsenic; Aspartate Aminotransferases; Caprylates; Gluconeogenesis; Kinetics; Liver; Mitochondria, Liver; Pyruvates; Rats; Serine | 1978 |
Studies on soybean trypsin inhibitors. IV. Change of the inhibitory activity of Bowman-Birk inhibitor upon replacements of the alpha-chymotrypsin reactive site serine residue by other amino acids.
Topics: Alanine; Binding Sites; Chymotrypsin; Glycine; Leucine; Serine; Structure-Activity Relationship; Trypsin Inhibitor, Bowman-Birk Soybean; Trypsin Inhibitors; Valine | 1978 |
Specific glycine uptake by identified neurons of Aplysia californica. II. Biochemistry.
Topics: Alanine; Animals; Aplysia; Biological Transport, Active; Culture Techniques; Ganglia; Glycine; Leucine; Neurons; Osmolar Concentration; Serine; Sodium; Temperature | 1978 |
Amino acid content of erythrocytes in uremia.
Topics: Alanine; Amino Acids; Erythrocytes; Histidine; Humans; Renal Dialysis; Serine; Tyrosine; Uremia | 1978 |
Characteristics of the transport of alanine, serine and glutamine across the plasma membrane of isolated rat liver cells.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Animals; Biological Transport; Cell Membrane; Glutamine; In Vitro Techniques; Kinetics; Liver; Male; Ouabain; Rats; Serine; Sodium | 1978 |
Comparative studies of alanine and alpha-aminoisobutyric acid uptake by freshly isolated rat liver cells.
Topics: Alanine; Aminoisobutyric Acids; Animals; Biological Transport; Choline; In Vitro Techniques; Kinetics; Leucine; Liver; Male; Rats; Serine; Sodium | 1979 |
Biochemical observations following administration of taurine to patients with epilepsy.
Topics: Adolescent; Adult; Alanine; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Female; Glutamates; Glutamine; Glycine; Humans; Male; Middle Aged; Serine; Taurine; Time Factors | 1975 |
Studies on human dental plaque. 1. Physical and chemical characteristics and enzyme activities of pooled plaque extracts.
Topics: Alanine; Amylases; Betaine; Dental Caries; Dental Plaque; Glutamates; Glycine; Humans; Leucine; Muramidase; Periodontal Diseases; Saliva; Serine; Valine | 1975 |
[Physiological changes of amino acid secretion in 24-hour urine in adults].
Topics: Adult; Alanine; Amino Acids; Aminobutyrates; Chromatography; Cystinuria; Glycine; Humans; Lysine; Male; Middle Aged; Serine; Time Factors | 1975 |
[Amino acid pattern in endemic (Balkan-)nephropathy (author's transl)].
Topics: Adolescent; Adult; Alanine; Amino Acids; Bulgaria; Child; Citrulline; Cystine; Disease Reservoirs; Female; Glycine; Humans; Isoleucine; Leucine; Male; Methionine; Nephritis, Interstitial; Ornithine; Phenylalanine; Proline; Romania; Serine; Yugoslavia | 1976 |
The variability of human lambda-chain constant regions and some relationships to V-regions sequences.
Topics: Alanine; Amino Acid Sequence; Chromatography, Gel; Chromatography, Ion Exchange; Cystine; Electrophoresis, Paper; Glutamates; Glycine; Humans; Immunoglobulin lambda-Chains; Immunoglobulin Light Chains; Isoleucine; Leucine; Peptides; Proline; Serine; Thiazoles; Threonine; Valine | 1976 |
[Mode of action of D-amino acids on the biosynthesis of peptidoglycan (author's transl)].
Topics: Alanine; Amino Acid Sequence; Amino Acids; Arthrobacter; Bacillus subtilis; Corynebacterium; Lactobacillus; Peptidoglycan; Serine; Staphylococcus aureus | 1976 |
Overall mechanism and rate equation for O-acetylserine sulfhydrylase.
Topics: Alanine; Cysteine Synthase; Kinetics; Lyases; Serine; Structure-Activity Relationship | 1977 |
Comparison of transport at the anterior and posterior surfaces of the calf lens.
Topics: Alanine; Amino Acids; Animals; Arginine; Biological Transport; Cattle; Cysteine; Epithelium; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Kinetics; Lens, Crystalline; Leucine; Serine | 1977 |
Neutral amino acid transport in an established mouse lymphocytic cell line.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport; Cell Line; Kinetics; Leucine; Lymphocytes; Serine; Sodium; Temperature | 1977 |
Rate of protein synthesis in oocytes of Paracentrotus lividus.
Topics: Alanine; Animals; Egg Proteins; Female; Kinetics; Leucine; Lysine; Oocytes; Ovum; Sea Urchins; Serine; Zygote | 1976 |
Comparative study of extracellular amino acids in culture of human liver and fibroblastic cells.
Topics: Alanine; Amino Acids; Aspartic Acid; Cell Division; Cells, Cultured; Isoleucine; Lactates; Leucine; Liver; Methionine; Phenylalanine; Pyruvates; Serine | 1976 |
Spontaneous development of gluconeogenesis in fetal rat livers during incubation in organ culture.
Topics: Alanine; Animals; Gluconeogenesis; Glycerol; Lactates; Liver; Organ Culture Techniques; Rats; Serine; Time Factors | 1976 |
Responses of Megalodiscus temperatus miracidia to amino and sialic acids found in snail-conditioned water.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Glutamine; Glycine; Serine; Sialic Acids; Snails; Trematoda; Water | 1976 |
Turnover of transfer RNA species during development of the posterior silkgland of Bombyx mori L.
Topics: Alanine; Animals; Aspartic Acid; Bombyx; Glycine; Larva; Metamorphosis, Biological; RNA, Transfer; Sebaceous Glands; Serine; Threonine; Time Factors | 1976 |
Stereochemistry of the reaction of sheep liver threonine dehydratase. A nuclear magnetic resonance and optical rotatory dispersion study of its reaction pathway and products.
Topics: Alanine; Animals; Butyrates; Cysteine; Hydro-Lyases; Keto Acids; Liver; Magnetic Resonance Spectroscopy; Optical Rotatory Dispersion; Propionates; Serine; Sheep; Stereoisomerism; Threonine; Threonine Dehydratase | 1976 |
A chemotactic receptor for val(ala)-gly-ser-glu on human.
Topics: Alanine; Chemotaxis, Leukocyte; Eosinophils; Glutamine; Glycine; Receptors, Drug; Serine; Valine | 1976 |
Amino acid metabolism in Friedreich's ataxia.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Friedreich Ataxia; Glycine; Histidine; Humans; Isoleucine; Ornithine; Phenylalanine; Phosphatidylethanolamines; Sarcosine; Serine; Taurine; Tyrosine; Valine | 1976 |
Amino acid composition, distribution and origin of "tuft" protein in human and bovine dental enamel.
Topics: Alanine; Amelogenesis; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Dental Enamel; Dental Enamel Proteins; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Free amino acids and amines in human dental plaque.
Topics: Alanine; Amines; Amino Acids; Aminobutyrates; Aspartic Acid; Cadaverine; Chemical Fractionation; Chromatography, Thin Layer; Dansyl Compounds; Dental Plaque; Fluorescence; Fluorometry; Glutamates; Glycine; Histamine; Humans; Ion Exchange; Lysine; Proline; Putrescine; Serine; Threonine; Valine | 1975 |
Studies on convulsants in the isolated frog spinal cord. I. Antagonism of amino acid responses.
Topics: Alanine; Amino Acids; Aminocaproates; Aminoisobutyric Acids; Animals; Asparagine; Bicuculline; Convulsants; Cystathionine; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Imidazoles; In Vitro Techniques; Isomerism; Leucine; Membrane Potentials; Nerve Endings; Neurons, Afferent; Picrotoxin; Rana pipiens; Serine; Spinal Cord; Strychnine; Taurine; Threonine; Valine | 1975 |
Transport properties of merodiploids covering the dagA locus in Escherichia coli K-12.
Topics: Alanine; Biological Transport, Active; Cell Membrane; Diploidy; Escherichia coli; Genes; Glycerol; Glycine; Kinetics; Leucine; Mutation; Proline; Serine; Stereoisomerism | 1975 |
Amino-acid incorporation into tRNA fragments and into heterologous combinations of fragments.
Topics: Alanine; Binding Sites; Escherichia coli; Kinetics; Magnesium; Nucleic Acid Conformation; Nucleic Acid Hybridization; Phenylalanine; Phenylalanine-tRNA Ligase; RNA, Transfer; Saccharomyces cerevisiae; Serine; Serine-tRNA Ligase; Species Specificity; Temperature; Transfer RNA Aminoacylation; Valine | 1975 |
Functional adaptation of aminoacyl-tRNA synthetases to fibroin biosynthesis in the silkgland of Bombyx mori L.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Bombyx; Fibroins; Glycine; Larva; Leucine; Metamorphosis, Biological; Protein Biosynthesis; Serine; Time Factors | 1975 |
Isolation of a new peptide antibiotic complex 61-26. Studies on antibiotics from the geneus Bacillus. V.
Topics: Alanine; Animals; Anti-Bacterial Agents; Aspartic Acid; Bacillus; Bacteria; Leucine; Mice; Peptides; Serine; Valine | 1975 |
The role of serine-123 in the activity and specificity of ribonuclease. Reactivation of ribonuclease 1-118 by the synthetic COOH-terminal tetradecapeptide, ribonuclease 111-124, and its O-methylserine and alanine analogs.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Binding Sites; Chromatography, Ion Exchange; Kinetics; Oligopeptides; Peptide Fragments; Peptides; Protein Binding; Ribonucleases; Serine | 1975 |
Uptake and metabolism of glutamate by isolated toad brains containing different levels of endogenous amino acids.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Biological Transport; Brain; Bufonidae; gamma-Aminobutyric Acid; Glutamates; Glutamine; Kinetics; Osmolar Concentration; Serine; Time Factors | 1975 |
The terminal amino acids of protein sequences and protein maturation.
Topics: Alanine; Amino Acid Sequence; Asparagine; Cell Nucleus; Codon; Glutamine; Lysine; Methionine; Peptide Chain Termination, Translational; Peptide Hydrolases; Phenylalanine; Protein Biosynthesis; Serine | 1975 |
The requirements of the brain for some amino acids.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Brain; Carbon Radioisotopes; Glycine; Kinetics; Proline; Rats; Serine; Sulfur Radioisotopes; Time Factors | 1975 |
On the mechanism of action of antibiotics which act as irreversible enzyme inhibitors.
Topics: Alanine; Anti-Bacterial Agents; Asparagine; Azaserine; Azo Compounds; Carbamates; Catalysis; Cell Wall; Cephalosporins; Cycloserine; Diazooxonorleucine; Enzyme Inhibitors; Glutamine; Models, Chemical; Models, Molecular; Penicillins; Purines; Pyridoxal Phosphate; Pyrimidines; Racemases and Epimerases; Serine | 1975 |
The involvement of mitochondrial pyruvate transport in the pathways of gluconeogenesis from serine and alanine in isolated rat and mouse liver cells.
Topics: Alanine; Animals; Cinnamates; Gluconeogenesis; Glutamine; Glycerol; Lactates; Liver; Mice; Mitochondria, Liver; Oxygen Consumption; Pyruvates; Rats; Serine; Tryptophan | 1975 |
Synthesis by conventional methods of human growth hormone peptide fragments. I.
Topics: Alanine; Asparagine; Aspartic Acid; Glutamine; Growth Hormone; Histidine; Humans; Leucine; Lysine; Optical Rotation; Peptides; Phenylalanine; Serine; Threonine; Tyrosine | 1975 |
Compartmentation of amino acid metabolism in the rat posterior pituitary.
Topics: Acetates; Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Radioisotopes; Dansyl Compounds; gamma-Aminobutyric Acid; Glucose; Glutamates; Glycine; Pituitary Gland, Posterior; Rats; Serine; Taurine; Tritium | 1975 |
Stimulated amino acid imbalance and histidine transport in rat brain slices.
Topics: Alanine; Amino Acids; Amino Acids, Dicarboxylic; Amino Acids, Essential; Aminoisobutyric Acids; Animals; Biological Transport, Active; Brain; Brain Chemistry; Diet; Dietary Proteins; Dose-Response Relationship, Drug; Glycine; Histidine; Kinetics; Male; Phenylalanine; Rats; Serine | 1975 |
Plasma amino acid levels and development of hepatic gluconeogenesis in the newborn rat.
Topics: Acetoacetates; Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Animals, Newborn; Blood Glucose; Fasting; Fatty Acids, Nonesterified; Glucagon; Gluconeogenesis; Glutamine; Glycerol; Hydroxybutyrates; Insulin; Lactates; Liver; Pyruvates; Rats; Serine | 1975 |
[Isolation and amino acid composition of two pathologically augmented proteins from psoriatic scales (author's transl)].
Topics: Alanine; Amino Acids; Electrophoresis, Disc; Galactosamine; Glycine; Humans; Leucine; Proteins; Psoriasis; Serine; Skin; Threonine | 1975 |
Developmental changes of free amino acids in bovine fetal fluids with gestational age and the interrelationships between the amino acid concentrations in the fluid compartments.
Topics: Alanine; Allantois; Amino Acids; Amniotic Fluid; Animals; Body Fluids; Cattle; Female; Fetal Blood; Fetus; Gastric Mucosa; Gestational Age; Methionine; Ornithine; Pregnancy; Serine; Stomach; Taurine; Threonine | 1975 |
[Some indices of nitrogen metabolism in patients with viral hepatitis].
Topics: Adolescent; Adult; Alanine; Ammonia; Asparagine; Chronic Disease; Cysteine; Cystinuria; Glutamates; Glycine; Hepatitis A; Humans; Isoleucine; Leucine; Methionine; Middle Aged; Nitrogen; Phenylalanine; Serine; Threonine; Urea; Valine | 1975 |
Characterization of neutral amino acid transport in a marine pseudomonad.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport, Active; Glycine; Isoleucine; Kinetics; Leucine; Mutation; Pseudomonas; Seawater; Serine; Stereoisomerism; Threonine; Valine; Water Microbiology | 1975 |
Compartmentalization of amino acids in surfactant aggregates. Partitioning between water and aqueous micellar sodium deodecanoate and between hexane and dodecylammonium propionate trapped water in hexane.
Topics: Alanine; Alkanes; Amino Acids; Arginine; Aspartic Acid; Colloids; Glutamates; Glycine; Isoleucine; Laurates; Leucine; Lysine; Micelles; Phenylalanine; Proline; Serine; Solubility; Threonine; Valine | 1975 |
Acetylation of Protein N-terminal amino groups structural observations on alpha-amino acetylated proteins.
Topics: Acetylation; Alanine; Amino Acid Sequence; Chemical Phenomena; Chemistry; Peptides; Protein Conformation; Proteins; Serine; Structure-Activity Relationship | 1975 |
Amino acid biosynthesis in mixed rumen cultures.
Topics: Alanine; Amino Acids; Animals; Bacteria; Cattle; Citric Acid Cycle; Female; Fumarates; Isoleucine; Ketoglutaric Acids; Leucine; Lysine; Oxaloacetates; Oxidation-Reduction; Phenylalanine; Propionates; Pyruvates; Rumen; Serine; Tyrosine; Valine | 1975 |
[Free amino acids in the amniotic fluid and in maternal blood in advanced pregnancy].
Topics: Alanine; Amino Acids; Amniotic Fluid; Cysteine; Female; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Pregnancy Trimester, Third; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Nutrition of Vitreoscilla stercoraria.
Topics: Alanine; Amino Acids; Aspartic Acid; Cysteine; Glutamates; Glutamine; Proline; Serine; Thiotrichaceae | 1975 |
Synthetic analogues of residues 1-34 of human parathyroid hormone: influence of residue number 1 on biological potency in vitro.
Topics: Adenylyl Cyclases; Alanine; Animals; Kidney; Parathyroid Hormone; Rats; Serine; Structure-Activity Relationship | 1975 |
Studies on trypsin inhibitors. Part I. Synthesis of protected peptides related to sequence 1-10 of porcine pancreatic secretory trypsin inhibitor II (Kazal).
Topics: Alanine; Animals; Arginine; Cysteine; Glutamine; Peptides; Proline; Serine; Swine; Threonine; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Valine | 1976 |
Inhibition of chicken pyruvate kinases by amino acids.
Topics: Alanine; Animals; Binding, Competitive; Chickens; Genetic Variation; Isoenzymes; Kinetics; Macromolecular Substances; Phenylalanine; Phosphoenolpyruvate; Protein Conformation; Pyruvate Kinase; Serine | 1976 |
Quantitative adaptation of isoacceptor tRNAs to mRNA codons of alanine, glycine and serine.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Bombyx; Codon; Glycine; RNA, Messenger; RNA, Transfer; RNA, Viral; Serine | 1976 |
[The pattern of distribution of free amino acids in human amniotic fluid related to the duration of pregnancy. Part I: Changes in concentration in normal pregnancy (author's transl)].
Topics: Alanine; Amino Acids; Amniotic Fluid; Chromatography, Gas; Cysteine; Female; Gestational Age; Glycine; Humans; Hydroxyproline; Methionine; Ornithine; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1976 |
Biosynthesis of amino acids from 3-(14C)-pyruvate in the fiddler crab Uca pugilator.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brachyura; Glutamates; Glutamine; Proline; Protein Biosynthesis; Pyruvates; Serine; Time Factors | 1976 |
Characterization of the stabilizing effect of point mutations of pyruvate oxidase from Lactobacillus plantarum: protection of the native state by modulating coenzyme binding and subunit interaction.
Topics: Alanine; Amino Acid Sequence; Asparagine; Enzyme Stability; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Kinetics; Lactobacillus; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Proline; Protein Denaturation; Pyruvate Oxidase; Recombinant Proteins; Serine; Spectrophotometry, Ultraviolet; Thiamine Pyrophosphate; Urea; Valine | 1992 |
Contributions of conserved serine residues to the interactions of ligands with dopamine D2 receptors.
Topics: Adenylyl Cyclase Inhibitors; Alanine; Animals; Base Sequence; Benzamides; Cell Line; Glioma; Immunoblotting; Iodine Radioisotopes; Ligands; Molecular Sequence Data; Mutation; Nucleic Acid Hybridization; Pyrrolidines; Radioligand Assay; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D2; RNA, Messenger; Serine; Tumor Cells, Cultured | 1992 |
Serine residues responsible for tetracycline transport are on a vertical stripe including Asp-84 on one side of transmembrane helix 3 in transposon Tn10-encoded tetracycline/H+ antiporter of Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Antiporters; Aspartic Acid; Bacterial Proteins; Base Sequence; Biological Transport; Carrier Proteins; Cell Membrane; Cysteine; DNA Transposable Elements; DNA, Bacterial; Escherichia coli; Immunoblotting; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Repressor Proteins; Serine; Tetracycline; Threonine | 1992 |
Receptor occupancy and adenylate cyclase activation in AR 4-2J rat pancreatic acinar cell membranes by analogs of pituitary adenylate cyclase-activating peptides amino-terminally shortened or modified at position 1, 2, 3, 20, or 21.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alanine; Amino Acid Sequence; Animals; Arginine; Cell Membrane; Enzyme Activation; Hydrogen-Ion Concentration; Iodine Radioisotopes; Kinetics; Molecular Sequence Data; Neuropeptides; Pancreas; Peptide Fragments; Phenylalanine; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Conformation; Rats; Receptors, Cell Surface; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone; Sequence Homology, Nucleic Acid; Serine | 1992 |
Amino acid transport systems in the human hepatoma cell line Hep G2.
Topics: Alanine; Amino Acids; Biological Transport; Carcinoma, Hepatocellular; Humans; Kinetics; Lithium; Liver Neoplasms; Proline; Serine; Sodium; Tumor Cells, Cultured | 1992 |
The presence of free D-alanine, D-proline and D-serine in mice.
Topics: Alanine; Amino Acids; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; D-Amino-Acid Oxidase; Kidney; Mice; Mice, Mutant Strains; Proline; Serine; Stereoisomerism | 1992 |
Dynorphin increases extracellular levels of excitatory amino acids in the brain through a non-opioid mechanism.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Dialysis; Dynorphins; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine; Kinetics; Male; Neurotransmitter Agents; Peptide Fragments; Rats; Rats, Inbred Strains; Serine; Stereotaxic Techniques; Taurine; Threonine | 1992 |
Increased oncogenic potential of ErbB is associated with the loss of a COOH-terminal domain serine phosphorylation site.
Topics: 3T3 Cells; Alanine; Animals; Cell Transformation, Neoplastic; Chick Embryo; Glutamates; Glutamic Acid; Kinetics; Mice; Mutation; Oncogenes; Phosphorylation; Plasmids; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptor, ErbB-2; Serine | 1992 |
pH and kinetic isotope effects on the reductive half-reaction of D-amino acid oxidase.
Topics: Alanine; D-Amino-Acid Oxidase; Deuterium; Glycine; Hydrogen-Ion Concentration; Isotope Labeling; Kinetics; Mathematics; Models, Theoretical; Serine | 1992 |
Immunocytochemical and circadian biochemical analysis of neuroactive amino acids in the pineal gland of the rat: effect of superior cervical ganglionectomy.
Topics: Alanine; Analysis of Variance; Animals; Arginine; Aspartic Acid; Chromatography, High Pressure Liquid; Circadian Rhythm; Endothelium; Ganglia, Sympathetic; Ganglionectomy; Glutamates; Glutamic Acid; Glutamine; Immunohistochemistry; Male; Melatonin; Neuroglia; Pineal Gland; Rats; Rats, Sprague-Dawley; Serine; Taurine | 1992 |
Alpha-helix stability in proteins. I. Empirical correlations concerning substitution of side-chains at the N and C-caps and the replacement of alanine by glycine or serine at solvent-exposed surfaces.
Topics: Alanine; Bacterial Proteins; Enzyme Stability; Glycine; Mutagenesis; Protein Denaturation; Ribonucleases; Serine; Solvents; Thermodynamics; Urea | 1992 |
The presence of free D-serine, D-alanine and D-proline in human plasma.
Topics: Adult; Aged; Alanine; Amino Acids; Chromatography, High Pressure Liquid; Creatinine; Female; Humans; Male; Middle Aged; Proline; Reference Values; Serine; Stereoisomerism | 1992 |
Nicotinylalanine increases the formation of kynurenic acid in the brain and antagonizes convulsions.
Topics: Alanine; Animals; Anticonvulsants; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Extracellular Matrix; Hippocampus; Kidney; Kynurenic Acid; Liver; Male; Niacin; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine; Tryptophan | 1992 |
Serine-to-alanine substitutions at the amino-terminal region of phytochrome A result in an increase in biological activity.
Topics: Alanine; Amino Acid Sequence; Chromatography, Gel; Enzyme Stability; Immunoblotting; Molecular Sequence Data; Mutation; Nicotiana; Oryza; Phytochrome; Plants, Genetically Modified; Plants, Toxic; Serine; Structure-Activity Relationship | 1992 |
Determination of D- and L-amino acids in mouse kidney by high-performance liquid chromatography.
Topics: Alanine; Amino Acids; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Kidney; Mice; Proline; Serine; Stereoisomerism | 1992 |
Serine-376 contributes to the binding of substrate by ribulose-bisphosphate carboxylase/oxygenase from Anacystis nidulans.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Cyanobacteria; Cysteine; Enzyme Activation; Kinetics; Mutagenesis, Site-Directed; Protein Binding; Ribulose-Bisphosphate Carboxylase; Serine; Substrate Specificity; Threonine | 1992 |
Allosteric interactions coordinate catalytic activity between successive metabolic enzymes in the tryptophan synthase bienzyme complex.
Topics: Alanine; Allosteric Regulation; Catalysis; Glycerophosphates; Indoles; Kinetics; Multienzyme Complexes; Protein Conformation; Salmonella typhimurium; Serine; Spectrum Analysis; Tryptophan Synthase | 1992 |
Increasing the thermostability of the neutral proteinase of Bacillus stearothermophilus by improvement of internal hydrogen-bonding.
Topics: Alanine; Base Sequence; DNA, Bacterial; Enzyme Stability; Geobacillus stearothermophilus; Hot Temperature; Hydrogen; Metalloendopeptidases; Molecular Sequence Data; Mutagenesis, Site-Directed; Serine | 1992 |
The influence of strychnine-insensitive glycine receptor agonists and antagonists on generalized seizure thresholds.
Topics: Alanine; Amygdala; Animals; Glycine; Kindling, Neurologic; Kynurenic Acid; Male; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Serine; Strychnine | 1991 |
L-alanine binding sites and Na+, K(+)-ATPase in cilia and other membrane fractions from olfactory rosettes of Atlantic salmon.
Topics: Alanine; Animals; Binding Sites; Cell Membrane; Cilia; Hydrogen-Ion Concentration; Mercuric Chloride; Olfactory Mucosa; Salmon; Serine; Sodium-Potassium-Exchanging ATPase; Threonine | 1991 |
Specificity of amino acid transport in renal papilla: microinfusion of Henle's loops and vasa recta.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Glutamates; Glutamic Acid; Kidney Medulla; Kidney Tubules, Distal; Kinetics; Loop of Henle; Male; Models, Biological; Perfusion; Rats; Rats, Inbred Strains; Serine; Taurine | 1991 |
Endogenous cleavage of the Arg-379-Ala-380 bond in vitronectin results in a distinct conformational change which 'buries' Ser-378, its site of phosphorylation by protein kinase A.
Topics: Alanine; Amino Acid Sequence; Arginine; Glycoproteins; Heparin; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Phosphorylation; Protein Conformation; Protein Kinases; Serine; Thrombin; Vitronectin | 1991 |
Control of ligand specificity in cyclic nucleotide-gated channels from rod photoreceptors and olfactory epithelium.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Cattle; Cyclic AMP; Cyclic GMP; DNA Mutational Analysis; Electric Conductivity; Ion Channel Gating; Ion Channels; Ligands; Molecular Sequence Data; Photoreceptor Cells; Protein Kinases; Sequence Alignment; Serine; Smell; Threonine; Xenopus laevis | 1991 |
Role of an evolutionarily invariant serine for the stability of human carbonic anhydrase II.
Topics: Alanine; Binding Sites; Biological Evolution; Carbonic Anhydrases; Cysteine; Erythrocytes; Humans; Mutation; Protein Conformation; Serine | 1992 |
Aspartate 170 of the photosystem II reaction center polypeptide D1 is involved in the assembly of the oxygen-evolving manganese cluster.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Cyanobacteria; Kinetics; Manganese; Mutagenesis, Site-Directed; Oxygen; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Recombinant Proteins; Serine; Spectrometry, Fluorescence | 1992 |
Cytoplasmic high-level expression of a soluble, enzymatically active form of the Escherichia coli penicillin-binding protein 5 and purification by dye chromatography.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Carrier Proteins; Cell Membrane; Chromatography; Cloning, Molecular; Cytoplasm; Escherichia coli; Gene Expression; Hexosyltransferases; Molecular Sequence Data; Muramoylpentapeptide Carboxypeptidase; Mutagenesis, Site-Directed; Penicillin-Binding Proteins; Peptidyl Transferases; Plasmids; Promoter Regions, Genetic; Protein Sorting Signals; Serine | 1992 |
Kinetic studies of human immunodeficiency virus type 1 protease and its active-site hydrogen bond mutant A28S.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Catalysis; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Genes, Synthetic; Genetic Vectors; HIV Protease; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Serine | 1991 |
Stabilization of the neutral protease of Bacillus stearothermophilus by removal of a buried water molecule.
Topics: Alanine; Bacterial Proteins; Base Sequence; Enzyme Stability; Geobacillus stearothermophilus; Hydrogen Bonding; Metalloendopeptidases; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Serine; Water | 1991 |
Mutation of alanine 24 to serine in subunit c of the Escherichia coli F1F0-ATP synthase reduces reactivity of aspartyl 61 with dicyclohexylcarbodiimide.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Dicyclohexylcarbodiimide; DNA Mutational Analysis; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Genetic Complementation Test; Genetic Vectors; Molecular Sequence Data; Proton-Translocating ATPases; Sequence Alignment; Serine; Structure-Activity Relationship; Venturicidins | 1991 |
Expression, isolation, and characterization of an active site (serine 528----alanine) mutant of recombinant bovine prothrombin.
Topics: 1-Carboxyglutamic Acid; Alanine; Animals; Binding Sites; Cattle; Chromatography, Liquid; DNA; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enzyme Activation; Gene Expression Regulation; Mutation; Plasmids; Prothrombin; Recombinant Proteins; Serine; Viper Venoms | 1991 |
Human plasma and recombinant factor VII. Characterization of O-glycosylations at serine residues 52 and 60 and effects of site-directed mutagenesis of serine 52 to alanine.
Topics: Alanine; Amino Acid Sequence; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Factor VII; Factor X; Glycopeptides; Glycosylation; Humans; Kinetics; Mass Spectrometry; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Serine | 1991 |
Aminoaciduria as a marker of acute renal transplant rejection--a patient study.
Topics: Adolescent; Alanine; Amino Acids; Child; Child, Preschool; Creatinine; Female; Glycine; Graft Rejection; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Serine; Threonine | 1991 |
Antithrombin Cambridge II, 384 Ala to Ser. Further evidence of the role of the reactive centre loop in the inhibitory function of the serpins.
Topics: Aged; Alanine; Antithrombin III; Base Sequence; Binding Sites; Exons; Heparin; Humans; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Proline; Protein Conformation; Serine; Serpins; Threonine; Thrombophlebitis; United Kingdom | 1991 |
Perilymphatic fistula: analysis of free amino acids in middle ear microaspirates.
Topics: Alanine; Amino Acids; Chromatography, High Pressure Liquid; Ear, Middle; Erythrocytes; Fistula; Glutamine; Glycine; Humans; Labyrinth Diseases; Methionine; Perilymph; Serine | 1991 |
Analysis of neutral amino acid transport systems in the small intestine: a study of brush border membrane vesicles.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Culture Media; Cysteine; Guinea Pigs; Ileum; In Vitro Techniques; Leucine; Microvilli; Proline; Serine | 1991 |
Glomerulopressin production by isolated rat liver after amino acid infusion.
Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Analysis of Variance; Animals; Dinoprostone; Dose-Response Relationship, Drug; Female; Glucuronates; Infusions, Intravenous; Liver; Male; Muscle Tonus; Muscle, Smooth; Proline; Rats; Rats, Inbred Strains; Serine | 1991 |
Secondary structure and side-chain 1H and 13C resonance assignments of calmodulin in solution by heteronuclear multidimensional NMR spectroscopy.
Topics: Alanine; Amino Acid Sequence; Amino Acids, Branched-Chain; Amino Acids, Diamino; Amino Acids, Dicarboxylic; Animals; Asparagine; Binding Sites; Calcium; Calmodulin; Drosophila melanogaster; Glutamine; Glycine; Hydrogen Bonding; Leucine; Magnetic Resonance Spectroscopy; Methionine; Molecular Sequence Data; Molecular Structure; Proline; Recombinant Proteins; Serine; Solutions; Threonine | 1991 |
Plasminogen activation with single-chain urokinase-type plasminogen activator (scu-PA). Studies with active site mutagenized plasminogen (Ser740----Ala) and plasmin-resistant scu-PA (Lys158----Glu).
Topics: Alanine; Enzyme Activation; Enzyme Precursors; Escherichia coli; Fibrinolysin; Glutamates; Glutamic Acid; Humans; Kinetics; Lysine; Mutation; Plasminogen; Plasminogen Activators; Recombinant Proteins; Serine; Urokinase-Type Plasminogen Activator | 1990 |
Renal arginine synthesis: studies in vitro and in vivo.
Topics: Alanine; Ammonium Chloride; Animals; Arginine; Aspartic Acid; Citrulline; Glomerular Filtration Rate; Glutamates; Glutamic Acid; Glutamine; Glycine; In Vitro Techniques; Kidney Cortex; Kidney Tubules; Kinetics; Male; Rats; Rats, Inbred Strains; Serine | 1990 |
Binding of tissue-type plasminogen activator with human endothelial cell monolayers. Characterization of the high affinity interaction with plasminogen activator inhibitor-1.
Topics: Alanine; Binding Sites; Binding, Competitive; Cells, Cultured; Endothelium, Vascular; Humans; Kinetics; Mutation; Plasminogen Inactivators; Recombinant Proteins; Serine; Tissue Plasminogen Activator; Umbilical Veins | 1990 |
Alteration of the major phosphorylation site of eukaryotic protein synthesis initiation factor 4E prevents its association with the 48 S initiation complex.
Topics: Alanine; Cell-Free System; Centrifugation, Density Gradient; Chromatography, Affinity; Eukaryotic Initiation Factor-4E; Humans; Isoelectric Focusing; Kinetics; Mutation; Peptide Chain Initiation, Translational; Peptide Initiation Factors; Phosphorylation; Protein Biosynthesis; Reticulocytes; Serine; Transcription, Genetic | 1990 |
Cloning, sequencing, expression, and site-directed mutagenesis of the gene from Clostridium perfringens encoding pyruvoyl-dependent histidine decarboxylase.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Carboxy-Lyases; Cloning, Molecular; Clostridium perfringens; Enzyme Precursors; Escherichia coli; Histidine Decarboxylase; Lactobacillus; Molecular Sequence Data; Mutation; Recombinant Proteins; Sequence Homology, Nucleic Acid; Serine | 1990 |
Two-dimensional NMR studies of staphylococcal nuclease. 1. Sequence-specific assignments of hydrogen-1 signals and solution structure of the nuclease H124L-thymidine 3',5'-bisphosphate-Ca2+ ternary complex.
Topics: Alanine; Amino Acid Sequence; Calcium; Glycine; Isoleucine; Magnetic Resonance Spectroscopy; Micrococcal Nuclease; Molecular Sequence Data; Molecular Structure; Protein Conformation; Serine; Solutions; Threonine; Thymine Nucleotides; Valine | 1990 |
Effects of amino acid isomers on canine renal hemodynamics.
Topics: Alanine; Amino Acids; Animals; Dogs; Female; Glomerular Filtration Rate; Hemodynamics; Male; Proline; Renal Circulation; Serine; Stereoisomerism | 1990 |
Phosphorylation of the polymeric immunoglobulin receptor required for its efficient transcytosis.
Topics: Alanine; Animals; Aspartic Acid; Cell Line; Cell Membrane; Endocytosis; Immunoglobulin A; Kinetics; Ligands; Membrane Glycoproteins; Molecular Weight; Mutation; Phosphorylation; Rats; Receptors, Immunologic; Secretory Component; Serine | 1990 |
Positional independence and additivity of amino acid replacements on helix stability in monomeric peptides.
Topics: Alanine; Amino Acid Sequence; Circular Dichroism; Molecular Sequence Data; Peptides; Protein Conformation; Serine; Structure-Activity Relationship; Temperature | 1990 |
Linear dichroism studies of tryptophanase and its quasisubstrate complexes oriented in polyacrylamide gel.
Topics: Alanine; Binding Sites; Escherichia coli; Ligands; Oxindoles; Protein Binding; Protein Conformation; Serine; Spectrum Analysis; Threonine; Tryptophanase | 1990 |
Possible involvement of alanine and pyruvate in the regulation of glucose transport in heart muscle cells.
Topics: Alanine; Animals; Biological Transport, Active; Calcium; Cells, Cultured; Deoxyglucose; Female; Heart; Kinetics; Myocardium; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Serine; Valine | 1990 |
Reversible import of apocytochrome c into mitochondria.
Topics: Alanine; Animals; Apoproteins; Biological Transport; Cysteine; Cytochrome c Group; Cytochromes c; Drosophila melanogaster; Kinetics; Mice; Mice, Inbred ICR; Mitochondria, Liver; Mutation; Protein Binding; Protein Biosynthesis; Serine; Transcription, Genetic | 1990 |
Na(+)-dependent transport of alanine and serine by liver plasma-membrane vesicles from rats fed a low-protein or a high-protein diet.
Topics: Alanine; Aminoisobutyric Acids; Animals; Biological Transport, Active; Ca(2+) Mg(2+)-ATPase; Cell Membrane; Dietary Proteins; Hydrogen-Ion Concentration; Kinetics; Lithium; Liver; Male; Rats; Rats, Inbred Strains; Serine; Sodium; Sodium-Potassium-Exchanging ATPase | 1990 |
Amino acid transport in membrane vesicles of Clostridium thermoautotrophicum.
Topics: Alanine; Amino Acids; Biological Transport, Active; Cell Membrane; Clostridium; Glycine; Kinetics; Protons; Serine | 1990 |
Pathway of proton transfer in bacterial reaction centers: replacement of serine-L223 by alanine inhibits electron and proton transfers associated with reduction of quinone to dihydroquinone.
Topics: Alanine; Benzoquinones; Chlorophyll; Electron Spin Resonance Spectroscopy; Electron Transport; Hydroquinones; Kinetics; Light-Harvesting Protein Complexes; Mutation; Oxidation-Reduction; Photosynthesis; Photosynthetic Reaction Center Complex Proteins; Plant Proteins; Protons; Quinones; Rhodobacter sphaeroides; Serine | 1990 |
Molecular basis for the inhibition of prostanoid biosynthesis by nonsteroidal anti-inflammatory agents.
Topics: Acetylation; Alanine; Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; DNA; DNA Restriction Enzymes; Exons; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Hybridization; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Serine; Sheep | 1990 |
Theoretical study of the packing of alpha-helices into possible transmembrane bundles. Sequences including alanines, leucines and serines.
Topics: Alanine; Amino Acid Sequence; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Ion Channels; Leucine; Membrane Proteins; Protein Conformation; Serine; Thermodynamics | 1987 |
The proton pore of the F0F1-ATPase of Escherichia coli: Ser-206 is not required for proton translocation.
Topics: Alanine; Amino Acid Sequence; Asparagine; Base Sequence; Dicyclohexylcarbodiimide; DNA Restriction Enzymes; DNA, Bacterial; Escherichia coli; Fluorescence; Glutamine; Ion Channels; Oxidative Phosphorylation; Proton-Translocating ATPases; Protons; Quinacrine; Serine | 1988 |
The primary role of the P1 residue (ser359) of alpha-1-proteinase inhibitor.
Topics: Alanine; alpha 1-Antitrypsin; Amino Acid Sequence; Binding Sites; Blood Proteins; Chromatography; Electrophoresis, Polyacrylamide Gel; Humans; Kinetics; Molecular Weight; Mutation; Neutrophils; Pancreatic Elastase; Peptide Fragments; Peptide Hydrolases; Protein Conformation; Serine; Serine Endopeptidases; Structure-Activity Relationship | 1989 |
Nature of the renal hemodynamic action of amino acids in dogs.
Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Anesthesia, General; Animals; Dogs; Female; Glomerular Filtration Rate; Liver; Male; Proline; Renal Circulation; Serine; Splanchnic Circulation | 1989 |
Characteristics of acidic, basic and neutral amino acid transport in the perfused rat hindlimb.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Female; Glutamates; Glycine; Hindlimb; Insulin; Kinetics; Lysine; Methylhistidines; Proline; Rats; Rats, Inbred Strains; Sarcolemma; Serine; Sodium | 1989 |
Xylosyl transfer to the core protein precursor of the rat chondrosarcoma proteoglycan.
Topics: Acetylgalactosamine; Aggrecans; Alanine; Animals; Chondrosarcoma; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix Proteins; Fucose; Glycoproteins; Immunosorbent Techniques; Lectins, C-Type; Mannose; Molecular Weight; Neoplasm Proteins; Protein Precursors; Protein Processing, Post-Translational; Proteoglycans; Rats; Serine; Tumor Cells, Cultured; Xylose | 1989 |
Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation.
Topics: Alanine; Base Sequence; Camphor 5-Monooxygenase; Cloning, Molecular; Cytochrome P-450 Enzyme System; Escherichia coli; Genes, Bacterial; Kinetics; Mixed Function Oxygenases; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Oxygen Consumption; Plasmids; Pseudomonas; Serine; Threonine; Valine | 1989 |
Some observations on the replacement of the conserved amino acid residues of immunoglobulin domains.
Topics: Alanine; Amino Acids; beta 2-Microglobulin; Computer Graphics; Cysteine; Immunoglobulin Constant Regions; Immunoglobulin Variable Region; Immunoglobulins; Leucine; Serine; Tryptophan; Tyrosine | 1989 |
Plasma amino acid concentrations in premature infants: effect of sampling site.
Topics: Alanine; Amino Acids; Aspartic Acid; Blood Specimen Collection; Capillaries; Chromatography, High Pressure Liquid; Glycine; Heel; Histidine; Humans; Infant, Newborn; Infant, Premature; Serine; Tryptophan; Veins | 1989 |
[The direct and indirect antiaggregation action of sodium hypochlorite on thrombocyte-enriched blood plasma].
Topics: Alanine; Animals; Bilirubin; Blood Platelets; Drug Interactions; Glutathione; Plasma; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Serine; Sodium Hypochlorite | 1989 |
Effect of impact trauma on neurotransmitter and nonneurotransmitter amino acids in rat spinal cord.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kinetics; Laminectomy; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Serine; Spinal Cord; Spinal Cord Injuries; Taurine; Threonine | 1989 |
P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance.
Topics: Adrenal Glands; Alanine; Amino Acid Sequence; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Cell Line; Cloning, Molecular; DNA; Drug Resistance; Genetic Vectors; Glycine; Humans; Membrane Glycoproteins; Molecular Sequence Data; Polymorphism, Genetic; Serine; Tumor Cells, Cultured | 1989 |
Substitution of amino acids in helix F of bacteriorhodopsin: effects on the photochemical cycle.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Bacteriorhodopsins; Glutamates; Glutamic Acid; Glutamine; Glycine; Hydrogen Bonding; Kinetics; Leucine; Molecular Sequence Data; Mutation; Phenylalanine; Photochemistry; Proline; Protons; Serine; Tryptophan | 1989 |
Splanchnic substrate balance in malnourished patients during parenteral nutrition.
Topics: Adipose Tissue; Alanine; Amino Acids, Branched-Chain; Cystine; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycine; Humans; Lipids; Liver; Male; Mesentery; Nitrogen; Parenteral Nutrition; Parenteral Nutrition, Total; Protein Biosynthesis; Protein-Energy Malnutrition; Serine; Splanchnic Circulation; Threonine; Tyrosine | 1985 |
Regulation and properties of the glutamine synthetase purified from Photobacterium phosphoreum.
Topics: Adenosine Monophosphate; Alanine; Catalysis; Cations, Divalent; gamma-Glutamyltransferase; Glutamate-Ammonia Ligase; Hydrogen-Ion Concentration; Molecular Weight; Photobacterium; Serine; Spectrophotometry, Ultraviolet | 1986 |
Differential changes in the content of amino acid neurotransmitters in discrete regions of the rat brain prior to the onset and during the course of homocysteine-induced seizures.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Corpus Striatum; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Hippocampus; Homocysteine; Hypothalamus; Inferior Colliculi; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Substantia Nigra; Taurine; Tissue Distribution | 1986 |
Glutamic acid as a putative transmitter of the interhemispheric corticocortical connections in the rat.
Topics: Alanine; Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Male; Rats; Rats, Inbred Strains; Serine; Threonine | 1986 |
The amino acid sequence of bovine thymus prothymosin alpha.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Cattle; Glutamates; Glutamic Acid; Humans; Molecular Sequence Data; Peptide Fragments; Protein Precursors; Rats; Serine; Species Specificity; Thymosin; Thymus Gland | 1988 |
Genetic mapping of a major site of phosphorylation in adenovirus type 2 E1A proteins.
Topics: Adenovirus Early Proteins; Adenoviruses, Human; Alanine; Animals; Cell Line; Cell Transformation, Viral; Cricetinae; HeLa Cells; Humans; Mutation; Oncogene Proteins, Viral; Peptide Fragments; Phenotype; Phosphoproteins; Phosphorylation; Protein Kinases; Serine | 1986 |
Echinococcus granulosus: absorption of cycloleucine and alpha-aminoisobutyric acid by protoscoleces.
Topics: Absorption; Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Cycloleucine; Diffusion; Echinococcus; Hydrogen-Ion Concentration; Leucine; Methionine; Proline; Serine; Valine | 1986 |
Effects of chronic uraemia on the formation of glucose and urea plus ammonia from L-alanine, L-glutamine and L-serine in isolated rat hepatocytes.
Topics: Acidosis; Alanine; Amino Acids; Ammonia; Animals; Gluconeogenesis; Glutaminase; Glutamine; In Vitro Techniques; L-Serine Dehydratase; Liver; Male; Phlorhizin; Rats; Rats, Inbred Strains; Serine; Urea; Uremia | 1986 |
Basolateral amino acid transport systems in the perfused exocrine pancreas: sodium-dependency and kinetic interactions between influx and efflux mechanisms.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Cell Membrane; Epithelium; Kinetics; Male; Pancreas; Phenylalanine; Rats; Rats, Inbred Strains; Serine; Sodium; Tritium | 1986 |
Linked metabolism of L-serine and L-alanine by Moniliformis moniliformis (Acanthocephala) in vitro.
Topics: Acanthocephala; Alanine; Amino Acids; Animals; Carbon Dioxide; Ethanol; Female; Male; Moniliformis; Serine | 1986 |
Characterization of carrier-mediated transport systems for small neutral amino acids in human fibroblast lysosomes.
Topics: Alanine; Amino Acids; Biological Transport, Active; Fibroblasts; Humans; Kinetics; Lysosomes; Mathematics; Osmolar Concentration; Proline; Serine; Sodium Chloride; Threonine | 1987 |
Neutral amino acid transport by membrane vesicles of Streptococcus cremoris is subject to regulation by internal pH.
Topics: Alanine; Amino Acids; Biological Transport; Cell Membrane; Cell-Free System; Diffusion; Hydrogen-Ion Concentration; In Vitro Techniques; Ionophores; Membrane Potentials; Serine; Streptococcus | 1987 |
Hemoglobin Knossos [alpha 2 beta 2(27)(B9)Ala----Ser] in Egypt.
Topics: Adult; Alanine; Amino Acids; Child; Egypt; Female; Hemoglobins, Abnormal; Humans; Male; Pedigree; Peptide Mapping; Serine | 1987 |
Hepatic serine and alanine metabolism during endotoxin-induced fever in sheep.
Topics: Alanine; Animals; Endotoxins; Escherichia coli; Fever; Liver; Male; Serine; Sheep; Sheep Diseases | 1987 |
Neutral amino acid transport in mouse peritoneal macrophages.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Cells, Cultured; Cysteine; Kinetics; Leucine; Macrophages; Male; Mice; Mice, Inbred C57BL; Serine; Tritium | 1987 |
Evidence for an alanine, serine, and cysteine system of transport in isolated brain capillaries.
Topics: Alanine; Animals; Biological Transport; Capillaries; Cerebrovascular Circulation; Cysteine; Female; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Serine; Sodium | 1987 |
The effects of vitamin B-6 deficiency in chronically azotemic and sham-operated rats.
Topics: Alanine; Animals; Asparagine; Aspartate Aminotransferases; Chronic Disease; Creatinine; Erythrocytes; Glycine; Rats; Serine; Urea; Uremia; Vitamin B 6 Deficiency | 1987 |
Substrate specificity of an acylaminopeptidase that catalyzes the cleavage of the blocked amino termini of peptides.
Topics: Alanine; Aminopeptidases; Dipeptides; Erythrocytes; Glycine; Humans; Methionine; Serine; Substrate Specificity; Valine | 1988 |
Characterization of a novel L-serine transport system in Escherichia coli.
Topics: Alanine; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane; Culture Media; Escherichia coli; Glycine; Isoleucine; Kinetics; Potassium Cyanide; Serine; Threonine; Valine | 1988 |
The interaction of aminogroups with pyrroloquinoline quinone as detected by the reduction of nitroblue tetrazolium.
Topics: Alanine; Animals; Cattle; Glycine; Histidine; Humans; Lysine; Nitroblue Tetrazolium; Oxidation-Reduction; PQQ Cofactor; Quinolines; Serine; Sheep; Swine; Tetrazolium Salts; Valine | 1988 |
Sodium-dependent transport of neutral amino acids by whole cells and membrane vesicles of Streptococcus bovis, a ruminal bacterium.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Cell Membrane; Glucose; Membrane Potentials; Rumen; Serine; Sodium; Streptococcus; Threonine | 1988 |
Increased oxygen affinity with normal heterotropic effects in hemoglobin Loire [alpha 88(F9)Ala----Ser].
Topics: 2,3-Diphosphoglycerate; Adult; Alanine; Amino Acids; Bezafibrate; Carbon Monoxide; Child; Chromatography, High Pressure Liquid; Diphosphoglyceric Acids; Electrophoresis; Hemoglobin A; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Isoelectric Focusing; Kinetics; Macromolecular Substances; Male; Oxygen; Phytic Acid; Serine | 1988 |
Inhibition of serine palmitoyltransferase in vitro and long-chain base biosynthesis in intact Chinese hamster ovary cells by beta-chloroalanine.
Topics: Acyltransferases; Alanine; Animals; beta-Alanine; Biological Transport, Active; Cells, Cultured; Cricetinae; Female; In Vitro Techniques; Lipids; Microsomes, Liver; Rats; Serine; Serine C-Palmitoyltransferase; Sphingolipids; Sphingosine | 1988 |
Influence of natural and recombinant interleukin 2 on endothelial cell arachidonate metabolism. Induction of de novo synthesis of prostaglandin H synthase.
Topics: 6-Ketoprostaglandin F1 alpha; Alanine; Arachidonic Acid; Arachidonic Acids; Blotting, Western; Chromatography, High Pressure Liquid; Cycloheximide; Cysteine; Dactinomycin; Endothelium, Vascular; Enzyme Induction; Epoprostenol; Humans; Interleukin-2; Molecular Weight; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Serine; Structure-Activity Relationship; Tissue Plasminogen Activator; von Willebrand Factor | 1988 |
Isolation and initial characterization of tumoricidal monokine(s) from the human monocytic leukemia cell line THP-1.
Topics: Alanine; Catalase; Cell Line; Cloning, Molecular; Cytotoxicity, Immunologic; Electrophoresis, Polyacrylamide Gel; Humans; Kinetics; Leukemia, Myeloid; Molecular Weight; Monocytes; Monokines; Protease Inhibitors; Proteins; Serine; Valine | 1985 |
Presence and quantity of dehydroalanine in histidine ammonia-lyase from Pseudomonas putida.
Topics: Alanine; Ammonia-Lyases; Binding Sites; Catalysis; Cyanides; Dimethyl Suberimidate; Histidine Ammonia-Lyase; Macromolecular Substances; Molecular Weight; Peptide Fragments; Pseudomonas; Serine; Structure-Activity Relationship | 1985 |
Glycine transport in mouse eggs and preimplantation embryos.
Topics: Alanine; Animals; Biological Transport; Blastocyst; Carbon; Cells, Cultured; Energy Metabolism; Female; Glycine; Mice; Oocytes; Serine; Sodium; Temperature | 1985 |
A new Na+-independent transport system for dipolar amino acids apparently corresponding to systems persisting after erythrocyte maturation in some mammalian genotypes.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Columbidae; Cysteine; Erythrocyte Aging; Erythrocytes; Horses; Kinetics; Serine; Sheep; Sodium; Species Specificity; Threonine | 1985 |
The activation of Mg++-dependent ATPase by aspartic and glutamic acids.
Topics: Adenosine Triphosphatases; Alanine; Asparagine; Aspartic Acid; Cell Membrane; Cell Membrane Permeability; Depression, Chemical; Enzyme Activation; Erythrocytes; Glutamates; Glutamine; Glycine; Humans; In Vitro Techniques; Leucine; Magnesium; Potassium; Saponins; Serine; Sodium | 1970 |
Antigenic and C-substance activities of related glycopeptides from fungal, parasitic and vegetable sources.
Topics: Alanine; Antigen-Antibody Reactions; Antigens; Ascaris; Aspartic Acid; Aspergillus; C-Reactive Protein; Cross Reactions; Epidermophyton; Epitopes; Galactose; Glutamates; Glycopeptides; Mannose; Peptides; Plants; Polysaccharides, Bacterial; Serine; Skin Tests; Threonine; Trichophyton | 1971 |
Immunological studies on the major haptenic peptides from performic acid oxidized ferredoxin from Clostridium pasteurianum.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Antibody Formation; Antigens; Aspartic Acid; Binding Sites; Carbon Isotopes; Clostridium; Complement Fixation Tests; Complement System Proteins; Dialysis; Electrophoresis; Epitopes; Ferredoxins; Formates; Glutamates; Glutamine; Haptens; Immune Sera; Immunoglobulin G; Isoleucine; Lysine; Oxidation-Reduction; Peptides; Proline; Rabbits; Serine; Tyrosine; Valine | 1971 |
The clonal nature of antibody formation. 3. Independence of antibody cell clones to poly-O-acetyl-D-serine and poly-D-alanine.
Topics: Alanine; Animals; Antibody Formation; Antibody Specificity; Antibody-Producing Cells; Clone Cells; gamma-Globulins; Haptens; Hemolytic Plaque Technique; Immune Sera; Immunodiffusion; Isoantigens; Mice; Muramidase; Ovalbumin; Rabbits; Serine; Serum Albumin, Bovine; Spleen | 1972 |
Studies on the enzymes involved in the biosynthesis of cyclo-tris (N-2,3-dihydroxybenzoyl-L-seryl) in Escherichia coli: kinetic properties of the L-serine-activating enzyme.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Anti-Bacterial Agents; Drug Stability; Enzyme Induction; Escherichia coli; Ethylmaleimide; Glycine; Gramicidin; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Phosphates; Phosphorus Radioisotopes; Proline; Serine; Threonine; Time Factors; Tritium; Tyrosine | 1973 |
Accumulation of neutral amino acids by Streptococcus faecalis. Energy coupling by a proton-motive force.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Biological Transport, Active; Carbon Radioisotopes; Carboxylic Acids; Cycloserine; Dicyclohexylcarbodiimide; Energy Metabolism; Enterococcus faecalis; Glycine; Glycolysis; Hydrogen-Ion Concentration; Kinetics; Membrane Potentials; Models, Biological; Mutation; Polycyclic Compounds; Potassium; Serine; Sodium; Threonine; Time Factors; Valinomycin | 1973 |
Studies on the elimination reaction of D-amino acid oxidase with -amino- -chlorobutyrate. Further evidence for abstraction of substrate -hydrogen as a proton.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Apoproteins; Catalysis; Chlorine; D-Amino-Acid Oxidase; Deuterium; Hydrogen; Isomerism; Keto Acids; Kidney; Kinetics; Osmolar Concentration; Oxidation-Reduction; Oxygen Consumption; Protons; Serine; Spectrophotometry; Swine; Temperature; Threonine; Tritium | 1973 |
Lysine transport in turtle ventricle. II. Effect of extracellular ions and ouabain on lysine fluxes.
Topics: Alanine; Animals; Arginine; Biological Transport; Carbon Radioisotopes; Choline; Cystine; Glycine; Heart; In Vitro Techniques; Inulin; Kinetics; Lysine; Myocardium; Ornithine; Ouabain; Potassium; Serine; Sodium; Time Factors; Tritium; Turtles | 1973 |
Interconversion of glycine and serine in a synaptosome fraction isolated from the spinal cord, medulla oblongata, telencephalon, and cerebellum of the rat.
Topics: Alanine; Animals; Aspartic Acid; Carbon Radioisotopes; Cerebellum; Female; Glutamates; Glutamine; Glycine; In Vitro Techniques; Medulla Oblongata; Neurotransmitter Agents; Rats; Serine; Spinal Cord; Synaptosomes; Telencephalon; Threonine | 1973 |
Radiochemical determination of the optical purity of L-amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Carbon Radioisotopes; Catalase; D-Amino-Acid Oxidase; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Methionine; Phenylalanine; Selenium; Serine; Stereoisomerism; Tritium; Tyrosine; Valine | 1974 |
Growth and extracellular lipids of certain pathogenic fungi in presence of different concentrations of amino acids.
Topics: Alanine; Amino Acids; Candida; Cystine; Extracellular Space; Fungi; Hydroxyproline; Lipid Metabolism; Microsporum; Phenylalanine; Serine; Species Specificity; Trichophyton | 1974 |
On the peptidoglycan of the cell walls of Pseudomonas aeruginosa. Structure of the peptide side chains.
Topics: Alanine; Amino Acids, Diamino; Arginine; Catalase; Cell Wall; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; D-Amino-Acid Oxidase; Dansyl Compounds; Glutamates; Lysine; Molecular Conformation; Peptidoglycan; Pimelic Acids; Protein Conformation; Pseudomonas aeruginosa; Serine | 1974 |
The effect of changes in external salinity on the non-protein nitrogenous constituents of parietal muscle from Agonus cataphractus.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Body Water; Ethionine; Fishes; Glutamates; Glutamine; Glycine; Lysine; Methionine; Muscles; Nitrogen; Osmolar Concentration; Potassium; Seawater; Serine; Sodium; Sodium Chloride; Taurine; Threonine | 1974 |
[Relation between gamma-aminobutyric acid and tyrosine metabolism and changes in the brain and liver amino acid content in intact and adrenalectomized rats].
Topics: Adrenal Glands; Adrenalectomy; Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine; Liver; Lysine; Male; Rats; Serine; Stimulation, Chemical; Threonine; Tyrosine | 1972 |
Effect of amino acids on the growth and phospholipid composition of some pathogenic fungi.
Topics: Alanine; Amino Acids; Arthrodermataceae; Candida; Candida albicans; Culture Media; Cystine; Fungi; Hydroxyproline; Microsporum; Phenylalanine; Phospholipids; Serine; Trichophyton | 1974 |
Comparison of the amino acid sequences of the variable regions of light chains derived from two homogeneous rabbit anti-pneumococcal antibodies.
Topics: Aconitic Acid; Alanine; Amino Acid Sequence; Amino Acids; Animals; Antibodies, Bacterial; Asparagine; Aspartic Acid; Autoanalysis; Chromatography, Gel; Electrophoresis, Paper; Glutamates; Glycine; Hydrolysis; Immunoglobulin Fragments; Rabbits; Serine; Streptococcus pneumoniae; Threonine; Tyrosine; Valine | 1974 |
Studies in immunoglobulin chemistry. I. Reinvestigation of the C-terminal amino acids of 6.5S rabbit and human gamma-globulins.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; gamma-Globulins; Glycine; Humans; Hydrazines; In Vitro Techniques; Peptides; Rabbits; Serine; Species Specificity; Sulfonic Acids | 1966 |
Chromatographic analysis of the bleeding sap of inoculated and non-inoculated soya plants.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; Chromatography, Paper; Glutamine; Glycine max; Injections; Leucine; Nitrogen; Rhizobium; Serine; Valine | 1967 |
A blocked N-terminal residue in the light chain of rabbit immunoglobulin G.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Chromatography, Paper; Electrophoresis; gamma-Globulins; Glutamates; Glycine; Hydrogen-Ion Concentration; Leucine; Peptide Hydrolases; Rabbits; Serine; Threonine; Valine | 1968 |
Argininosuccinic aciduria in hereditary hair diseases.
Topics: Adolescent; Adult; Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Chromatography, Paper; Cystinuria; Female; Glutamates; Glutamine; Glycine; Hair; Histidine; Humans; Infant; Lysine; Male; Middle Aged; Serine; Skin Diseases; Threonine; Tyrosine; Valine | 1968 |
Inhibition of cell division in Micrococcus lysodeikticus dis-II.
Topics: Alanine; Aspartic Acid; Cell Division; Cell Wall; Culture Media; Depression, Chemical; Glycols; Lactones; Lysine; Magnesium; Micrococcus; Microscopy, Electron; Microscopy, Phase-Contrast; Microtomy; Mitomycins; Mucoproteins; Penicillins; Serine; Staining and Labeling; Stereoisomerism | 1970 |
Plasma and red blood cell amino acids of Egyptian children suffering from protein--calorie malnutrition.
Topics: Alanine; Amino Acids; Child, Preschool; Chromatography, Paper; Diet Therapy; Egypt; Erythrocytes; Follow-Up Studies; Glutamine; Glycine; Humans; Infant; Infant Nutrition Disorders; Isoleucine; Kwashiorkor; Leucine; Methionine; Protein-Energy Malnutrition; Serine; Valine | 1973 |
NH2-terminal amino acid distribution and amino acid composition of Streptococcus faecalis R soluble and ribosomal proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aspartic Acid; Autoanalysis; Bacterial Proteins; Cell-Free System; Culture Media; Dinitrophenols; Enterococcus faecalis; Folic Acid; Glutamates; Glycine; Methionine; Ribosomes; Serine; Solubility; Threonine | 1973 |
Gluconeogenesis from amino acids in mature wether sheep.
Topics: Alanine; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Blood Glucose; Carbon Dioxide; Carbon Radioisotopes; Energy Metabolism; Gluconeogenesis; Glucose; Glutamates; Male; Oxidation-Reduction; Parenteral Nutrition; Serine; Sheep; Structure-Activity Relationship | 1973 |
Role of methionine in biosynthesis of prodigiosin by Serratia marcescens.
Topics: Alanine; Aspartic Acid; Carbon Radioisotopes; Cell-Free System; Chemical Phenomena; Chemistry; Culture Media; Escherichia coli; Glutamates; Histidine; Methionine; Methyltransferases; Mutation; Prodigiosin; Proline; Pseudomonas aeruginosa; S-Adenosylmethionine; Serine; Serratia marcescens; Stereoisomerism; Tetrahydrofolates | 1973 |
Characterization of degradation products of the cell wall released during growth and sporulation of Bacillus megaterium.
Topics: Alanine; Aspartic Acid; Bacillus megaterium; Carbon Radioisotopes; Cell Wall; Chromatography, Gel; Glucosamine; Glycine; Muramic Acids; Peptidoglycan; Phosphorus; Phosphorus Radioisotopes; Pimelic Acids; Serine; Spores, Bacterial; Time Factors | 1974 |
D-amino acids in the cell pool of bacteria.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Bacillus subtilis; Bacteria; Chromatography, Thin Layer; Clostridium; Culture Media; Escherichia coli; Glutamates; Histidine; Hydrogen-Ion Concentration; Lactobacillus; Leucine; Proline; Serine; Spectrophotometry; Staphylococcus; Stereoisomerism; Temperature; Tyrosine | 1974 |
Formation of D-alanyl-D-alanine and D-alanine from UDPMurNAc-L-Ala-D-isoGlu-L-Lys-D-Ala-D-Ala by extracts of Staphylococcus aureus and Streptococcus faecalis.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Carbon Radioisotopes; Chromatography, Paper; Dipeptides; Enterococcus faecalis; Muramic Acids; Oligopeptides; Penicillin G; Peptide Synthases; Phosphates; Serine; Species Specificity; Staphylococcus; Sugar Acids; Uracil Nucleotides | 1974 |
Active transport of D-alanine and related amino acids by whole cells of Bacillus subtilis.
Topics: Alanine; Amino Acids; Azides; Bacillus subtilis; Biological Transport, Active; Carbon Radioisotopes; Cycloserine; Depression, Chemical; Electron Transport; Glycine; Kinetics; Serine; Stereoisomerism | 1974 |
[The inducibility of aspartate-ammonium lyase of Pseudomonas fluorescence (type R)].
Topics: Alanine; Ammonia-Lyases; Aspartate Ammonia-Lyase; Aspartic Acid; Buffers; Chloramphenicol; Depression, Chemical; Dinitrophenols; Enzyme Induction; Glutamates; Glycine; Oxygen; Pseudomonas fluorescens; Serine; Stimulation, Chemical; Structure-Activity Relationship | 1974 |
[Effect of different thiols on renal excretion of water and osmotically active substances in the rabbit].
Topics: Absorption; Alanine; Animals; beta-Aminoethyl Isothiourea; Cysteine; Dimercaprol; Kidney Concentrating Ability; Kidney Tubules; Osmolar Concentration; Penicillamine; Rabbits; Serine; Urine | 1968 |
[Effect of mercaptans on urine volume and osmolarity in rabbits].
Topics: Alanine; Animals; beta-Aminoethyl Isothiourea; Cysteine; Dimercaprol; Female; Kidney; Osmolar Concentration; Penicillamine; Rabbits; Receptors, Drug; Serine; Sodium Chloride; Thiosulfates; Urine; Vasopressins | 1969 |
[Influence of changes in urinary pH on the excretion of amino acids from the isolated perfused rat kidney].
Topics: Alanine; Amino Acids; Animals; Arginine; Diffusion; Glycine; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Leucine; Lysine; Perfusion; Rats; Serine; Threonine; Tyrosine; Urine; Valine | 1967 |
Biosynthesis of the peptidoglycan of bacterial cell walls. XVII. Biosynthesis of peptidoglycan and of interpeptide bridges in Lactobacillus viridescens.
Topics: Alanine; Carbon Isotopes; Chromatography, Gel; Chromatography, Thin Layer; Enzymes; Glucosamine; Glycosaminoglycans; Hydrogen-Ion Concentration; Kinetics; Lactobacillus; Lysine; Peptide Biosynthesis; RNA, Transfer; Serine; Uracil Nucleotides | 1970 |
Biosynthesis of the peptidoglycan of bacterial cell walls. 18. Purification and properties of L-alanyl transfer ribonucleic acid-uridine diphosphate-N-acetylmuramyl-pentapeptide transferase from Lactobacillus viridescens.
Topics: Alanine; Carbon Isotopes; Cell Wall; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Paper; Chromatography, Thin Layer; Cysteine; Electrophoresis; Electrophoresis, Disc; Glycine; Glycosaminoglycans; Hydrogen-Ion Concentration; Lactobacillus; Molecular Weight; Nickel; Oxidation-Reduction; RNA, Transfer; Serine; Transferases; Uracil Nucleotides | 1970 |
The structure of the cell wall peptidoglycan of Bifidobacterium bifidum var. pennsylvanicus.
Topics: Alanine; Amino Acids; Ammonia; Asparagine; Cell Wall; Chromatography, Gel; Chromatography, Paper; Cycloserine; Dinitrophenols; Electrophoresis; Fluorine; Glucosamine; Glutamine; Glycosaminoglycans; Hydrazines; Hydrolysis; Lactobacillus; Models, Structural; Muramidase; Nucleoside Diphosphate Sugars; Ornithine; Paper; Peptides; Polysaccharides, Bacterial; Serine; Species Specificity; Stereoisomerism; Uracil Nucleotides | 1971 |
Elimination and sulfite addition as a means of localization and identification of substituted seryl and threonyl residues in proteins and proteoglycans.
Topics: Alanine; Alkylation; Aminobutyrates; Animals; Binding Sites; Cartilage; Caseins; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Ion Exchange; Glucagon; Glycoproteins; Glycosaminoglycans; Mucins; Optical Rotatory Dispersion; Oxidation-Reduction; Phosphoproteins; Proteins; Serine; Submandibular Gland; Sulfites; Sulfones; Sulfonic Acids; Sulfur Isotopes; Swine; Threonine; Trypsin | 1972 |
The peptides of the hyphal wall of Neurospora crassa.
Topics: Alanine; Amino Acids; Cell Wall; Chitinases; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Thin Layer; Glycopeptides; Hydrolysis; Molecular Weight; Neurospora; Neurospora crassa; Peptides; Protein Binding; Quaternary Ammonium Compounds; Serine | 1973 |
[Participation of different C-14-compounds in the biosynthesis of labeled mithramycin].
Topics: Acetates; Actinomyces; Alanine; Carbon Radioisotopes; Methionine; Phenylalanine; Plicamycin; Serine | 1974 |
Micromethod for the quantitative determination of L-alanine.
Topics: Alanine; Aminobutyrates; Cysteine; Isoleucine; Kinetics; Microchemistry; NAD; Serine; Spectrum Analysis; Valine | 1965 |
Structure of amino acyl oligonucleotides from T-1 ribonuclease digests of soluble ribonucleic acid charged with serine, glycine, threonine, and alanine.
Topics: Alanine; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Glycine; Phosphoric Monoester Hydrolases; Polynucleotides; Ribonucleases; RNA, Transfer; Serine; Spectrophotometry; Threonine; Venoms | 1966 |
[Use of amino acids and pathogenic and non-pathogenic E. coli with increased resistance to a number of antibiotics in experiments in vitro and in the process of treatment of patients with colienteritis].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Child; Chloramphenicol; Chlortetracycline; Colistin; Drug Resistance, Microbial; Enteritis; Escherichia coli; Escherichia coli Infections; Glutamates; Glycine; Humans; In Vitro Techniques; Oxytetracycline; Proline; Serine; Streptomycin; Viomycin | 1967 |
The intraspinal distribution of some depressant amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain Chemistry; Cats; Depression, Chemical; Freezing; Glutamates; Glutamine; Glycine; Receptors, Drug; Serine; Spinal Cord; Spinal Nerves; Strychnine; Synapses; Synaptic Transmission; Taurine; Tissue Extracts | 1968 |
Deacylated transfer ribonucleic acid as a factor for peptide chain initiation in rabbit reticulocyte systems.
Topics: Acetates; Alanine; Animals; Carbon Isotopes; Chromatography, Paper; Formates; Genetic Code; Globins; Leucine; Magnesium; Methionine; Peptide Biosynthesis; Periodic Acid; Phenylalanine; Rabbits; Reticulocytes; RNA, Transfer; Serine; Tritium; Valine | 1968 |
Cyanide metabolism in higher plants. 3. The biosynthesis of beta-cyanolanine.
Topics: Alanine; Amino Acids; Asparagine; Carbon Isotopes; Colorimetry; Cyanides; Cysteine; Hydro-Lyases; Hydrogen Cyanide; Plants; Serine; Stimulation, Chemical | 1968 |
The effects of dietary protein on the hepatic enzymes of serine metabolism in the rabbit.
Topics: Alanine; Animals; Caseins; Depression, Chemical; Diet; Dietary Proteins; Glycerol; Glycerolphosphate Dehydrogenase; Hydro-Lyases; Liver; Male; Phosphoric Monoester Hydrolases; Phosphotransferases; Protein Deficiency; Puromycin; Pyruvates; Rabbits; Serine; Time Factors; Transaminases | 1969 |
Tetanus toxin and amino acid levels in cat spinal cord.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cats; Glycine; Injections; Serine; Spinal Cord; Synaptic Transmission; Tetanus Toxin | 1969 |
Electron paramagnetic resonance study of free radical products of the reaction of ninhydrin with amino acids, peptides and proteins.
Topics: Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Dipeptides; Electron Spin Resonance Spectroscopy; Ethanol; Free Radicals; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Lysine; Peptides; Phenylalanine; Proline; Proteins; Serine; Solutions; Tryptophan; Tyrosine; Valine | 1970 |
Amino acid sequence of cyanogen bromide peptides from the amino-terminal region of chick skicollagen.
Topics: Alanine; Amino Acid Sequence; Animals; Chickens; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cyanides; Lysine; Microbial Collagenase; Peptides; Rats; Serine; Skin; Species Specificity; Trypsin | 1970 |
The enzymatic synthesis of N-methylalanine.
Topics: Adenosine Triphosphate; Alanine; Amines; Autoradiography; Carbon Isotopes; Chromatography, Gel; Chromatography, Thin Layer; Crystallization; Electrophoresis; Folic Acid; Glutamates; Magnesium; NAD; Paper; Pseudomonas; Pyruvates; Serine | 1970 |
[Formation of free radicals in aliphatic amino acids and peptides under conditions of photosensitization by dyes].
Topics: Acridines; Alanine; Amino Acids; Coloring Agents; Electron Spin Resonance Spectroscopy; Fluoresceins; Free Radicals; Glycine; Leucine; Peptides; Photosensitivity Disorders; Riboflavin; Serine; Solutions | 1966 |
Regulation of the transport and metabolism of amino acids in isolated fat cells. Effect of insulin and a possible role for adenosine 3',5'-monophosphate.
Topics: Adenine Nucleotides; Adipose Tissue; Adrenocorticotropic Hormone; Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Butyrates; Carbon Isotopes; Cyclic AMP; Cyclopentanes; Epididymis; Glucose; Glycine; Hot Temperature; In Vitro Techniques; Insulin; Kinetics; Leucine; Male; Palmitic Acids; Protein Biosynthesis; Proteins; Puromycin; Rats; Serine; Sodium; Theophylline | 1970 |
Peptidyl-tRNA. XII. Behaviour of peptidyl-tRNA-Phe from Escherichia coli on methylated albumin silicic acid column.
Topics: Alanine; Albumins; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography; Electrophoresis; Escherichia coli; Glycine; Peptides; Phenylalanine; RNA, Transfer; Serine; Silicon Dioxide | 1971 |
[Comparison of some in vivo effects of cyclic 3',5'-GMP and cyclic 3',5'-AMP on glucolipid metabolism in the mouse].
Topics: Acetates; Adenine Nucleotides; Adipose Tissue; Alanine; Animals; Blood Glucose; Bone and Bones; Carbon Isotopes; Cyclic AMP; Cyclic GMP; Fatty Acids; Gluconeogenesis; Glycolipids; Guanine Nucleotides; Liver; Liver Glycogen; Male; Mice; Pyruvates; Serine; Stimulation, Chemical; Time Factors; Tritium | 1971 |
Photorespiration during C 4 photosynthesis.
Topics: Alanine; Alcohol Oxidoreductases; Aldehyde-Lyases; Aspartic Acid; Carbohydrates; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Chromatography, Ion Exchange; Electrophoresis; Folic Acid; Fructose; Glycerophosphates; Glycine; Glycolates; Glyoxylates; Hexosephosphates; Ligases; Malates; Oxidoreductases; Pentosephosphates; Phosphoric Monoester Hydrolases; Phosphotransferases; Photosynthesis; Plants; Pyruvates; Ribose; Serine; Sulfites; Transferases | 1971 |
Glycopeptides from silk fibroin of Bombyx mori.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Bombyx; Boron Compounds; Chromatography, Gel; Chromatography, Ion Exchange; Fibroins; Glucosamine; Glycine; Glycopeptides; Hydrolysis; Mannose; Molecular Weight; Oxidation-Reduction; Peptide Hydrolases; Peptides; Periodic Acid; Serine; Thiocyanates; Threonine; Trypsin | 1971 |
Properties and amino acid composition of polyoma virus purified by zonal ultracentrifugation.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Centrifugation, Density Gradient; Centrifugation, Zonal; Complement Fixation Tests; Erythrocytes; Hemagglutination Tests; Leucine; Lysine; Methionine; Methods; Polyomavirus; Serine; Sheep; Ultracentrifugation | 1968 |
Isolation of lysinoalanine from the protein-polysaccharide complex of cartilage after alkali treatment.
Topics: Acetamides; Acrylates; Alanine; Amino Acids; Animals; Benzyl Compounds; Cartilage; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Ion Exchange; Cystine; Electrophoresis, Paper; Formates; Hydrogenation; Hydrolysis; Hydroxides; Lysine; Mass Spectrometry; Periodic Acid; Polysaccharides; Potassium; Protein Binding; Proteins; Serine | 1971 |
Genetic and physiological control of serine and glycine biosynthesis in Saccharomyces.
Topics: Acetates; Alanine; Ammonium Sulfate; Aspartic Acid; Carbon Isotopes; Cell-Free System; Chemical Precipitation; Chromatography, Paper; Culture Media; Fluorides; Genetics, Microbial; Glucose; Glutamates; Glycerolphosphate Dehydrogenase; Glycerophosphates; Glycine; Glycolysis; Glyoxylates; Isocitrates; Lyases; Mutation; NAD; Oxidative Phosphorylation; Saccharomyces; Serine; Spectrophotometry; Transferases | 1972 |
[Comparative study of transfer ribonucleic acids extracted from rat liver and Zajdela hepatoma. I. Study of the acceptor properties of tRNA].
Topics: Acylation; Alanine; Animals; Arginine; Ascites; Carcinoma, Hepatocellular; Cell Differentiation; Cell Transformation, Neoplastic; Isoleucine; Kinetics; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats; RNA, Transfer; Serine; Transfer RNA Aminoacylation; Valine | 1972 |
Cofactor activity of protein components of human very low density lipoproteins in the hydrolysis of triglycerides by lipoproteins lipase from different sources.
Topics: Adipose Tissue; Alanine; Animals; Apoproteins; Blood Proteins; Cattle; Enzyme Activation; Glutamates; Heparin; Humans; Lipoprotein Lipase; Lipoproteins; Lipoproteins, VLDL; Male; Milk; Peptides; Phosphatidylcholines; Rats; Serine; Serum Albumin; Structure-Activity Relationship; Triglycerides | 1973 |
Enzymes of serine biosynthesis in Rhodopseudomonas capsulata.
Topics: Alanine; Alcohol Oxidoreductases; Carbon Radioisotopes; Cell-Free System; Chromatography, Ion Exchange; Chromatography, Paper; Glutamates; Glyceric Acids; Glycerolphosphate Dehydrogenase; Hydrazines; Kinetics; Magnesium; Organophosphorus Compounds; Phosphoric Monoester Hydrolases; Pyruvates; Rhodopseudomonas; Serine; Spectrophotometry, Ultraviolet; Tetrahydrofolates; Transaminases; Transferases | 1973 |
The isolation and the structure of new glycopeptide from blood group substances.
Topics: Acetamides; Alanine; Asparagine; Blood Group Antigens; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis, Paper; Galactosamine; Glucosamine; Glycopeptides; Humans; Optical Rotation; Oxidation-Reduction; Periodic Acid; Proline; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet | 1974 |
Effect of dorsal root section on amino acids of rat spinal cord.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Carbon Radioisotopes; Centrifugation, Density Gradient; Glutamates; Glutamine; Glycine; Lumbosacral Region; Lysine; Male; Mitochondria; Myelin Sheath; Nerve Degeneration; Nerve Endings; Nerve Tissue Proteins; Rats; Serine; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission; Tritium | 1974 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Polypeptide composition of rat high density lipoprotein: characterization by SDS-gel electrophoresis.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Apoproteins; Arginine; Carboxypeptidases; Dansyl Compounds; Electrophoresis, Polyacrylamide Gel; Kinetics; Lipoproteins, HDL; Male; Molecular Weight; Rats; Serine; Sucrose; Time Factors | 1974 |
Regulation of aspartate family amino acid biosynthesis in Brevibacterium flavum. I. Inhibition by amino acids of the enzymes in threonine biosynthesis.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acids; Aspartate-Semialdehyde Dehydrogenase; Aspartic Acid; Brevibacterium; Cysteine; Glutathione; Isoleucine; Lyases; Lysine; Methionine; Phosphotransferases; Serine; Temperature; Threonine | 1968 |
The oxidation of glycine by D-amino acid oxidase in extracts of mammalian central nervous tissue.
Topics: Alanine; Animals; Aspartic Acid; Benzoates; Carbon Isotopes; Cats; Central Nervous System; Cerebellum; Cerebral Cortex; D-Amino-Acid Oxidase; Glycine; Ketones; Mercury; Oxidation-Reduction; Pyrans; Serine; Spinal Cord; Tissue Extracts | 1969 |
Intracellular localization of enzymes in leaves and chloroplast membrane permeability to compounds involved in amino acid syntheses.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acid Oxidoreductases; Amino Acids; Aspartate Aminotransferases; Aspartic Acid; Carbon Dioxide; Chloroplasts; Glutamate Dehydrogenase; Glutamates; Glutathione Reductase; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycine; Isocitrate Dehydrogenase; Malate Dehydrogenase; NAD; NADP; Nicotiana; Oxidoreductases; Plants; Plants, Edible; Plants, Toxic; Pyruvate Kinase; Serine | 1969 |
Characterization of ferredoxin from nutsedge, Cyperus rotundus L., and other species with a high photosynthetic capacity.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Bacteria; Biological Evolution; Carbon Dioxide; Chlorophyll; Chloroplasts; Cytochromes; Dicarboxylic Acids; Electron Spin Resonance Spectroscopy; Electrophoresis, Disc; Ferredoxins; Glycine; Hydrogen-Ion Concentration; Iron; Molecular Weight; NADP; Pentosephosphates; Peptides; Photochemistry; Photosynthesis; Plant Proteins; Plants; Serine; Species Specificity; Spectrophotometry; Sulfur | 1970 |
Physiology of interferonogenesis. II. Mechanism of action of alanine and serine on interferon production in chick embryo fibroblast cultures.
Topics: Alanine; Animals; Antimetabolites; Chick Embryo; Chloromercuribenzoates; Culture Techniques; Cycloserine; Dinitrophenols; Fibroblasts; Interferons; Iodoacetates; Orthomyxoviridae; Serine; Sodium; Stereoisomerism | 1971 |
Studies on the mechanism of action of D-amino acid oxidase. Evidence for removal of substrate -hydrogen as a proton.
Topics: Alanine; Chemical Phenomena; Chemistry; Chlorine; D-Amino-Acid Oxidase; Deuterium; Flavin-Adenine Dinucleotide; Hydrogen; Hydrogen-Ion Concentration; Keto Acids; Kinetics; Models, Chemical; Nitrogen; Oxygen; Phenylhydrazines; Proline; Protons; Pyruvates; Quaternary Ammonium Compounds; Serine; Spectrophotometry; Stereoisomerism; Thiosemicarbazones; Tritium; Ultraviolet Rays | 1971 |
D-Alanine: membrane acceptor ligase from Lactobacillus casei.
Topics: Acetates; Adenosine Triphosphate; Alanine; Amides; Aminobutyrates; Carbon Isotopes; Cell Membrane; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; D-Amino-Acid Oxidase; Dipeptides; Diphosphates; Enzyme Activation; Hydrogen-Ion Concentration; Hydroxamic Acids; Hydroxylamines; Isomerases; Kinetics; Lacticaseibacillus casei; Lactobacillus; Ligases; Magnesium; Micropore Filters; Nitrates; Phosphorus Isotopes; Potassium; Potassium Chloride; Serine; Sodium; Sodium Chloride; Stereoisomerism; Subcellular Fractions; Ultracentrifugation | 1971 |
Chinese hamster liver glutamine synthetase. Purification, physical and biochemical properties.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Amino Acids; Animals; Azo Compounds; Binding Sites; Centrifugation, Density Gradient; Chromatography, Gel; Chromatography, Ion Exchange; Cricetinae; Cytosine Nucleotides; Diazooxonorleucine; Electrophoresis; Ethylmaleimide; Glutamate-Ammonia Ligase; Glutamates; Ketoglutaric Acids; Kinetics; Liver; Macromolecular Substances; Molecular Weight; Phosphates; Serine; Tritium | 1972 |
Absorption of some amino acids by the haemoflagellate, Trypanosoma gambiense.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Transport; Carbon Isotopes; Cysteine; Glutamates; Glycine; Iodoacetates; Kinetics; Leucine; Lysine; Ornithine; Rats; Serine; Threonine; Trypanosoma brucei gambiense | 1972 |
Isolation and identification of pharmacologically active amino acids in skin and their structure-activity relationship on the guinea-pig ileum.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Atropine; Chromatography, Ion Exchange; Esters; Guinea Pigs; Histamine H1 Antagonists; Humans; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Proline; Rabbits; Rats; Receptors, Drug; Serine; Skin; Structure-Activity Relationship; Tissue Extracts | 1972 |
Rat liver glutamine synthetase. Preparation, properties, and mechanism of inhibition by carbamyl phosphate.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Animals; Binding Sites; Carbamates; Catalysis; Electrophoresis, Disc; Enzyme Activation; Glutamate-Ammonia Ligase; Glutamates; Glycine; Ketoglutaric Acids; Liver; Macromolecular Substances; Magnesium; Manganese; Methionine Sulfoximine; Molecular Weight; Phosphoric Acids; Protein Binding; Rats; Serine; Tritium; Ultracentrifugation | 1972 |
Enzymic oxidation of some resistant D-amino acids.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Cattle; D-Amino-Acid Oxidase; Glutamates; Indicators and Reagents; Kidney; Liver; Lysine; Methionine; Methods; Oxidation-Reduction; Serine; Swine; Threonine; Time Factors | 1972 |
Lipolytic and hypoglycemic compounds obtained from cystoseira barbata J. Ag.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Blood Glucose; Chromatography, Gel; Chromatography, Paper; Eukaryota; Glutamine; Histidine; Leucine; Lipid Metabolism; Lysine; Methionine; Peptide Fragments; Rabbits; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Kinetic properties of pyruvate kinases from turtle liver and heart.
Topics: Alanine; Allosteric Regulation; Animals; Binding Sites; Citrates; Cysteine; Enzyme Activation; Fructosephosphates; Hexosediphosphates; Hydrogen-Ion Concentration; Isoleucine; Ketoglutaric Acids; Kinetics; Liver; Magnesium; Methionine; Myocardium; Organ Specificity; Phenylalanine; Phosphoenolpyruvate; Protein Binding; Pyruvate Kinase; Serine; Succinates; Tryptophan; Turtles; Valine | 1974 |
Report on the utilization of ethanolamine-1-14C by Mycobacterium 607.
Topics: Alanine; Carbon Radioisotopes; Chromatography, Paper; Ethanolamines; Glycine; Mycobacterium; Organophosphorus Compounds; Phosphatidylethanolamines; Serine | 1974 |
The antigenicity of two closely related sequential polyheptapeptides.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Antibody Formation; Antigens; Autoanalysis; Circular Dichroism; Dialysis; Female; Guinea Pigs; Immunity, Cellular; Immunization; Injections, Intraperitoneal; Magnetic Resonance Spectroscopy; Male; Molecular Weight; Peptides; Protein Conformation; Serine; Skin Tests | 1974 |
The existence of multiple conformational forms in anhydrochymotrypsin.
Topics: Acetophenones; Alanine; Alkylation; Binding Sites; Chymotrypsin; Circular Dichroism; Dialysis; Drug Stability; Freeze Drying; Kinetics; Methionine; Nitro Compounds; Plants; Protein Binding; Protein Conformation; Serine; Spectrophotometry, Ultraviolet; Time Factors; Trypsin Inhibitors | 1974 |
Plasma concentrations of tryptophan and other amino acids in manic-depressive patients.
Topics: Alanine; Arginine; Aspartic Acid; Bipolar Disorder; Emotions; Glutamates; Glycine; Humans; Isoleucine; Leucine; Methionine; Psychology; Serine; Threonine; Tryptophan; Tyrosine | 1974 |
[Amino acid levels in the blood serum of patients with chronic colitis].
Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Betaine; Chronic Disease; Citrulline; Colitis; Glutamates; Glutamine; Glycine; Histidine; Humans; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tryptophan; Tyrosine; Urea | 1974 |
L-phenylalanine interactions with structurally related substances at the intestinal mucosa.
Topics: Alanine; Amino Acids; Animals; Binding Sites; Binding, Competitive; Biological Transport; Carbon Radioisotopes; Cysteine; Dihydroxyphenylalanine; Female; Intestinal Mucosa; Intestine, Small; Jejunum; Kinetics; Phenylalanine; Rats; Receptors, Drug; Serine; Time Factors | 1974 |
Serine-glyoxylate aminotransferase from kidney bean (Phaseolus vulgaris). II. The reverse reactions.
Topics: Acetates; Alanine; Ammonia; Carbon Radioisotopes; Chromatography, Ion Exchange; Ethylmaleimide; Glyoxylates; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Kinetics; Nitrates; Plants; Potassium Chloride; Pyruvates; Serine; Time Factors; Transaminases | 1974 |
Analogues of human calcitonin. I. Influence of modifications in amino acid positions 29 and 31 on hypocalcaemic activity in the rat.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Calcitonin; Calcium; Dose-Response Relationship, Drug; Female; Hypocalcemia; Photometry; Rats; Regression Analysis; Serine; Structure-Activity Relationship; Threonine; Time Factors; Valine | 1974 |
Amino acid transport in human placental slices.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Biological Transport, Active; Carbon Radioisotopes; Chromatography, Paper; Extracellular Space; Female; Glutamates; Glycine; Humans; In Vitro Techniques; Kidney; Leucine; Lysine; Placenta; Pregnancy; Proline; Rats; Serine; Time Factors | 1974 |
Kinetic studies on the alkali-catalyzed hydrolysis and epimerization of model alkyl and hydroxyalkyl di- and tripeptides.
Topics: Alanine; Alcohols; Alkanes; Borates; Chemical Phenomena; Chemistry; Dipeptides; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Leucine; Oligopeptides; Optical Rotation; Phosphates; Serine; Stereoisomerism; Threonine | 1974 |
[Free amino acids in the 24 h urine of healthy children (author's transl)].
Topics: Adolescent; Age Factors; Alanine; Amino Acids; Aminobutyrates; Carnosine; Child; Chromatography, Ion Exchange; Citrulline; Female; Glycine; Histidine; Humans; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Serine; Sex Factors; Threonine; Tyrosine; Valine | 1974 |
Free amino acids in the haemocytes and plasma of the larva of Calliphora vicina.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Blood Cells; Blood Coagulation; Diptera; Glutamates; Glutamine; Glycine; Hemolymph; Histidine; Isoleucine; Larva; Leucine; Lysine; Methionine; Phenylalanine; Plasma; Proline; Serine; Taurine; Threonine; Tyrosine; Valine | 1974 |
Navy (Haricot)-bean (Phaseolus vulgaris) lectin. Isolation and characterization of tow components from a toxic agglutinating extract.
Topics: Alanine; Animals; Aspartic Acid; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cysteine; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Glucosamine; Glycoproteins; Hemagglutination Tests; Horses; Lectins; Leucine; Leukocytes; Mannose; Methionine; Molecular Weight; Plant Lectins; Plants; Quail; Serine; Tryptophan | 1974 |
Study of serum amino acids in Egyptian lead workers.
Topics: Adult; Alanine; Amino Acids; Colorimetry; Egypt; Glutamates; Glycine; Histidine; Humans; Lead Poisoning; Leucine; Lysine; Male; Middle Aged; Proline; Serine; Tyrosine; Valine | 1974 |
Studies on the fractionation of total transfer ribonucleic acid and purification of an alanine transfer ribonucleic acid from chick embryo.
Topics: Alanine; Animals; Aspartic Acid; Chemical Fractionation; Chick Embryo; Chromatography, Ion Exchange; Histidine; Isoleucine; Lysine; Proline; Ribonucleases; RNA, Transfer; Serine; Tyrosine; Valine | 1974 |
Formate-induced labeling of the active site of aspartate aminotransferase by beta-chloro-L-alanine.
Topics: Acetates; Alanine; Animals; Aspartate Aminotransferases; Binding Sites; Borohydrides; Carbon Radioisotopes; Circular Dichroism; Formates; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Mitochondria, Muscle; Molecular Weight; Myocardium; Oxidation-Reduction; Propionates; Protein Binding; Protein Conformation; Protein Denaturation; Pyridoxal; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Swine; Time Factors | 1974 |
Mode of action on proteins of acid carboxypeptidase from Aspergillus saitoi.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Aspergillus; Carboxypeptidases; Cattle; Egg White; Hydrogen-Ion Concentration; Kinetics; Methods; Muramidase; Phenylalanine; Proline; Proteins; Ribonucleases; Serine; Surface-Active Agents; Time Factors; Valine | 1974 |
Amino acid and glucose uptake by the isolated perfused guinea-pig mammary gland.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Radioisotopes; Caseins; Female; Glucose; Glutamates; Guinea Pigs; Lactation; Mammary Glands, Animal; Organ Size; Perfusion; Pregnancy; Proline; Serine; Time Factors | 1974 |
Prebiotic synthesis of hydrophobic and protein amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Ammonia; Aspartic Acid; Autoanalysis; Chromatography, Gas; Glutamates; Glycine; Isoleucine; Leucine; Mass Spectrometry; Methane; Nitrogen; Proline; Serine; Threonine; Valine; Water | 1972 |
Two amino-acid carriers in pea chloroplasts.
Topics: Alanine; Amino Acids; Biological Transport; Cell Membrane Permeability; Chloroplasts; Diffusion; Glycine; Osmolar Concentration; Osmosis; Plants; Serine; Sucrose | 1972 |
[Amino acid concentration in plasma and blood cells during coli-L-asparaginase therapy].
Topics: Alanine; Amino Acids; Asparaginase; Asparagine; Autoanalysis; Erythrocytes; Glutamates; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Plasma; Serine; Time Factors | 1972 |
A sensitive double isotope derivative assay to measure release of amino acids from brain in vitro.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Asparagine; Carbon Isotopes; Cerebral Cortex; Dansyl Compounds; Electric Stimulation; Glutamates; Glycine; In Vitro Techniques; Isotope Labeling; Methods; Rats; Serine; Tritium; Valine | 1973 |
Tetanus toxin inhibits amino acid release from nerve endings in vitro.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Electric Stimulation; Glutamates; Glutamine; Glycine; In Vitro Techniques; Medulla Oblongata; Nerve Endings; Rats; Serine; Spinal Cord; Synaptic Vesicles; Synaptosomes; Tetanus Toxin | 1973 |
The role of amino acids as stimulants of antral release.
Topics: Acetylcholine; Alanine; Amino Acids; Animals; Choline; Cysteine; Dogs; Female; Gastric Fistula; Gastric Juice; Glycine; Histamine; Male; Pentagastrin; Phenylalanine; Pyloric Antrum; Secretory Rate; Serine; Stimulation, Chemical | 1974 |
Biosynthesis of 4-thiouridylate. Participation of a sulfurtransferase containing pyridoxal 5'-phosphate.
Topics: Alanine; Aldehydes; Borohydrides; Chromatography; Cysteine; Enzyme Activation; Escherichia coli; Hydroxyapatites; Hydroxylamines; Kinetics; Organophosphorus Compounds; Picolines; Pyridoxal Phosphate; Pyruvates; RNA, Transfer; Serine; Sulfhydryl Compounds; Sulfur Isotopes; Sulfurtransferases; Thiouridine; Uridine | 1972 |
An investigation of the decoding of triplets adjacent to AUG during initiation.
Topics: Alanine; Bacterial Proteins; Carbon Isotopes; Centrifugation, Density Gradient; Escherichia coli; Formaldehyde; Formates; Genetic Code; Guanine Nucleotides; Guanosine Triphosphate; Methionine; Peptide Biosynthesis; Peptide Chain Initiation, Translational; Ribosomes; RNA, Bacterial; RNA, Transfer; RNA, Viral; Serine; Tritium | 1972 |
The clonal nature of antibody formation. IV. Differential stimulation of antibody cell clones specific for poly-O-acetyl-D-serine and poly-D-alanine.
Topics: Alanine; Animals; Antibodies; Antibody Formation; Antibody Specificity; Antibody-Producing Cells; Binding Sites; Clone Cells; Genes; Hemolytic Plaque Technique; Mice; Serine; Spleen | 1972 |
Two fractionation methods for transfer RNAs.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Benzoates; Carbon Isotopes; Chromatography, DEAE-Cellulose; Countercurrent Distribution; Escherichia coli; Evaluation Studies as Topic; Hydrogen-Ion Concentration; Methods; Nucleic Acid Conformation; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Serine; Spectrophotometry, Ultraviolet; Transfer RNA Aminoacylation; Tritium; Urea | 1972 |
Studies on the formation of transfer ribonucleic acid-ribosome complexes. XXII. Binding of aminoacyl-oligonucleotides to ribosomes.
Topics: Adenine Nucleotides; Alanine; Amino Acids; Amino Acyl-tRNA Synthetases; Ammonium Chloride; Chromatography, Ion Exchange; Cytosine Nucleotides; Electrophoresis, Paper; Escherichia coli; Ethanol; Glutamates; Leucine; Lysine; Magnesium; Oligonucleotides; Phenylalanine; Polynucleotides; Puromycin; Ribosomes; Serine; Tritium | 1972 |
Synthesis and biological evaluation of 4-alanine-luteinizing hormone-releasing-releasing hormone ((ALA 4 )LH-RH).
Topics: Alanine; Amino Acids; Animals; Biological Assay; Castration; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Molecular Weight; Peptides; Pituitary Gland; Pituitary Hormone-Releasing Hormones; Radioimmunoassay; Rats; Receptors, Drug; Serine; Sheep; Structure-Activity Relationship | 1972 |
Glutamate transport in Escherichia coli K-12: nonidentity of carriers mediating entry and exit.
Topics: Alanine; Azides; Biological Transport, Active; Carbon Isotopes; Culture Media; Diffusion; Escherichia coli; Esters; Glutamates; Leucine; Methionine; Serine; Stereoisomerism; Sucrose | 1973 |
Purification and properties of dipeptidase M from Escherichia coli B.
Topics: Alanine; Ammonium Sulfate; Bacterial Proteins; Cations, Divalent; Chloromercuribenzoates; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Dipeptidases; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrogen-Ion Concentration; Iodoacetates; Kinetics; Macromolecular Substances; Methionine; Methods; Molecular Weight; Peptide Chain Initiation, Translational; Serine; Sodium Dodecyl Sulfate; Structure-Activity Relationship; Sulfhydryl Compounds; Urea | 1973 |
D-serine transport system in Escherichia coli K-12.
Topics: Alanine; Biological Transport, Active; Carbon Isotopes; Chromosome Mapping; Cycloserine; Drug Resistance, Microbial; Escherichia coli; Genes; Genetic Linkage; Glycine; L-Serine Dehydratase; Membrane Transport Proteins; Mutation; Recombination, Genetic; Serine; Stereoisomerism | 1973 |
Transport systems for alanine, serine, and glycine in Escherichia coli K-12.
Topics: Alanine; Autoradiography; Biological Transport, Active; Chromosome Mapping; Escherichia coli; Glycine; Leucine; Mutation; Serine; Stereoisomerism; Threonine; Transduction, Genetic | 1973 |
Multiplicity of leucine transport systems in Escherichia coli K-12.
Topics: Alanine; Bacterial Proteins; Biological Transport, Active; Chromatography, DEAE-Cellulose; Escherichia coli; Isoleucine; Leucine; Mutation; Nitrosoguanidines; Osmosis; Protein Binding; Serine; Stereoisomerism; Threonine; Transduction, Genetic; Valine | 1973 |
Regulation of biodegradative threonine deaminase. 3. Effects of beta substituents of substrate on absorption spectrum and circular dichroism of the enzyme-bound pyridoxal phosphate.
Topics: Alanine; Binding Sites; Chlorine; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Circular Dichroism; Escherichia coli; Hydro-Lyases; Hydroxylation; Kinetics; Molecular Conformation; Protein Binding; Pyridoxal Phosphate; Schiff Bases; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Stereoisomerism; Structure-Activity Relationship; Threonine; Time Factors; Valine | 1974 |
The psu1+ amber suppressor gene of bacteriophage T4: identification of its amino acid and transfer RNA.
Topics: Alanine; Autoradiography; Carbon Isotopes; Coliphages; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genes; Genetic Code; Genetics, Microbial; Glycine; Mutation; Phenotype; Phenylalanine; Phosphorus Isotopes; RNA, Transfer; RNA, Viral; Serine; Sulfur Isotopes; Suppression, Genetic; Valine; Viral Proteins | 1973 |
[Why does the gastric mucosa secrete pepsins and hydrochloric acid? (author's transl)].
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Carbohydrate Metabolism; Cholecystokinin; Dogs; Feedback; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Glycine; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Lipid Metabolism; Pepsin A; Peptide Hydrolases; Peptides; Proteins; Sarcosine; Serine; Stimulation, Chemical; Time Factors; Transfer RNA Aminoacylation; Trypsin | 1974 |
Nitrogen repression of the allantoin degradative enzymes in Saccharomyces cerevisiae.
Topics: Alanine; Allantoin; Amidohydrolases; Amino Acids; Ammonia; Arginase; Arginine; Asparagine; Carboxylic Acids; Enzyme Repression; Glucose; Lactates; Nitrogen; Saccharomyces cerevisiae; Serine; Time Factors; Urea | 1974 |
Nucleotide sequences of transfer ribonucleic acids.
Topics: Alanine; Arginine; Aspartic Acid; Base Sequence; Biological Evolution; Escherichia coli; Evaluation Studies as Topic; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Plants; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Serine; Species Specificity; Tryptophan; Tyrosine; Valine | 1974 |
Persisting circadian oscillations in enzyme activity in non-dividing cultures of Euglena.
Topics: Acid Phosphatase; Alanine; Alkaline Phosphatase; Amino Acid Oxidoreductases; Aminohydrolases; Cell Division; Circadian Rhythm; Darkness; Euglena gracilis; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; Kinetics; L-Lactate Dehydrogenase; Light; Serine; Threonine | 1972 |
Close correlation between changing content of specific amino acids in epileptogenic cortex of cats, and severity of epilepsy.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cats; Cerebral Cortex; Cobalt; Electroencephalography; Epilepsies, Partial; Epilepsy; Glutamates; Glutamine; Glycine; Motor Cortex; Serine; Taurine; Visual Cortex | 1972 |
The clonal nature of antibody formation. II. Characteristics of antibody cell clones specific for poly-O-acetyl-D-serine and poly-D-alanine.
Topics: Alanine; Animals; Antibody Formation; Antibody Specificity; Antibody-Producing Cells; Cell Division; Clone Cells; Haptens; Hemolytic Plaque Technique; Immune Sera; Immunodiffusion; Isoantigens; Mice; Peptides; Radiation Chimera; Serine; Spleen | 1972 |
Regulation of glyconeogenesis from amino acids by acetate in Tetrahymena pyriformis.
Topics: Acetates; Alanine; Alanine Transaminase; Amino Acids; Animals; Aspartate Aminotransferases; Carbon Isotopes; Cells, Cultured; Culture Media; Glucose; Glutamates; Glycogen; Isoleucine; Leucine; Serine; Tetrahymena pyriformis; Time Factors; Tyrosine | 1973 |
D- and L-isomers of serine and alanine equally effective as releasers of gastrin.
Topics: Alanine; Animals; Dogs; Gastrins; Glycine; Serine; Stereoisomerism; Stomach | 1972 |
Proline metabolism in Leishmania donovani promastigotes.
Topics: Alanine; Arginine; Aspartic Acid; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Glucose; Glutamates; Leishmania; Malate Dehydrogenase; Malates; Methionine; Methods; Oxygen Consumption; Proline; Pyruvates; Serine | 1972 |
Synthesis of sequence peptide polymers related to collagen.
Topics: Alanine; Amino Acid Sequence; Collagen; Glycine; Hydroxyproline; Methods; Peptides; Polymers; Proline; Serine | 1972 |
A study of stabilization of gluconeogenic activity in rat liver slices by calcium and manganese ions.
Topics: Alanine; Animals; Calcium; Carboxy-Lyases; Gluconeogenesis; Glucose; Glutamine; Glycerol; In Vitro Techniques; Lactates; Liver; Liver Glycogen; Lysosomes; Magnesium; Manganese; Phosphoenolpyruvate; Pyruvates; Rats; Serine | 1972 |
Amino acid metabolism in chameleon liver.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Citrulline; Female; Glutamates; Glutamine; Glycine; Histidine; Keto Acids; Liver; Lizards; Lysine; Male; Methionine; Ornithine; Phenylalanine; Pyruvates; Serine; Threonine; Tryptophan | 1972 |
[Blood-brain barrier and placental barrier for various amino acids in the mouse (whole body autoradiography studies)].
Topics: Alanine; Amino Acids; Animals; Autoradiography; Blood-Brain Barrier; Cell Membrane Permeability; Female; Glycine; Lysine; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Phenylalanine; Pregnancy; Serine; Tritium; Tyrosine | 1972 |
Research for amino acids in lunar samples.
Topics: Alanine; Amino Acids; Aspartic Acid; Astronomical Phenomena; Astronomy; Chromatography, Gas; Chromatography, Ion Exchange; Extraterrestrial Environment; Geological Phenomena; Geology; Glutamates; Glycine; Hydrolysis; Indicators and Reagents; Oxalates; Serine; Space Flight | 1972 |
Amino acids and peptides. 34. Synthesis of a structure related to scotophobin.
Topics: Alanine; Amino Acid Sequence; Asparagine; Aspartic Acid; Glutamine; Glycine; Lysine; Memory; Peptides; Serine; Tyrosine | 1972 |
Amino acid compositions of all the tryptic peptides from the and polypeptide chains of adult hemoglobin of the slow loris (Nycticebus coucang). Biochemical studies on hemoglobins and myoglobins. X.
Topics: Alanine; Amino Acids; Animals; Arginine; Chromatography; Chromatography, Paper; Glutamine; Hemoglobins; Histidine; Isoleucine; Leucine; Lysine; Methionine; Myoglobin; Peptides; Phenylalanine; Primates; Serine; Threonine; Trypsin; Tyrosine; Valine | 1972 |
Permeability of human buccal mucosa to an amino acid analogue, the antibiotic D-cycloserine.
Topics: Alanine; Cheek; Cycloserine; Humans; Hydrogen-Ion Concentration; Methionine; Mouth Mucosa; Proline; Serine | 1972 |
[Amino acid metabolism pathology in the convulsive syndrome in young children].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Child, Preschool; Cystine; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Infant; Infant, Newborn; Leucine; Lysine; Male; Methionine; Proline; Seizures; Serine; Tryptophan; Tyrosine; Valine | 1972 |
The metabolism of oxalate precursors in isolated perfused rat livers.
Topics: Alanine; Animals; Carbon Isotopes; Ethanolamines; Female; Glycine; Glycolates; Glycols; Glyoxylates; Kidney; Liver; Methionine; Oxalates; Oxidation-Reduction; Perfusion; Pyridoxine; Rats; Serine; Thiamine; Thiamine Deficiency; Time Factors; Vitamin B 6 Deficiency | 1972 |
Studies on protamines. XVI. The complete amino acid sequence of clupeine YII.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Chromatography; Fishes; Male; Proline; Protamines; Serine; Spermatozoa; Threonine; Valine | 1972 |
Studies on protamines. XVII. The complete amino acid sequence of clupeine YI.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Cell Nucleus; Chromatography; Fishes; Glycine; Isoleucine; Male; Proline; Protamines; Serine; Spermatozoa; Threonine | 1972 |
[Effect of certain amino acids on the thermostability of animal and plant cells and cellular models].
Topics: Alanine; Amino Acids; Animals; Anura; Chromatography, Paper; Electrophoresis, Paper; Epithelial Cells; Epithelium; Glycerol; Glycine; In Vitro Techniques; Magnoliopsida; Models, Biological; Oviducts; Protein Denaturation; Ranidae; Serine; Thermosensing; Tryptophan | 1972 |
Amino acid inhibition of a 1 -pyrroline-5-carboxylate dehydrogenase preparation from beef kidney mitochondria.
Topics: Alanine; Amino Acid Oxidoreductases; Amino Acids; Animals; Cattle; Glutamates; Glycine; Kidney; Leucine; Mitochondria; Pyrroles; Serine; Valine | 1972 |
Effect of D-alanine and D-aspartic acid on the chick.
Topics: Alanine; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Asparagine; Aspartic Acid; Body Weight; Chickens; Diet; Dietary Proteins; Dose-Response Relationship, Drug; Drug Synergism; Glutamates; Glycine max; Growth; Plant Proteins; Serine; Stereoisomerism; Structure-Activity Relationship; Vitamins | 1972 |
Evidence for induced fit of a pseudo-substrate of aspartate aminotransferase.
Topics: Alanine; Animals; Aspartate Aminotransferases; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Chlorine; Copper; Cytoplasm; Depression, Chemical; Formates; Glutamates; Kinetics; Myocardium; Pyridoxal Phosphate; Serine; Stimulation, Chemical; Sulfuric Acids; Swine | 1972 |
Interaction of 4-nitroquinoline 1-oxide and related carcinogens with histone and aliphatic amino acids.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carcinogens; Cattle; Chemical Phenomena; Chemistry; Glutamates; Glycine; Histones; Isoleucine; Leucine; Lysine; Methionine; Proline; Protein Denaturation; Quinolines; Serine; Spectrophotometry; Threonine; Thymus Gland; Valine | 1972 |
Concentration of alpha-amino nitrogen and free amino acid in the uterine and blastocoelic fluid of rabbit.
Topics: Alanine; Amines; Amino Acids; Amniotic Fluid; Animals; Asparagine; Autoanalysis; Blastocyst; Castration; Chromatography, Paper; Embryo Implantation; Estrus; Female; Fertilization; Glutamates; Glutamine; Glycine; Nitrogen; Pregnancy; Pregnancy, Animal; Rabbits; Serine; Time Factors | 1972 |
Enhancement of iron absorption from ligated segments of rat intestine by histidine, cysteine, and lysine: effects of removing ionizing groups and of stereoisomerism.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Chelating Agents; Chemical Phenomena; Chemistry; Cysteine; Deamination; Decarboxylation; Duodenum; Histidine; Intestine, Small; Ions; Iron; Iron Isotopes; Ligation; Lysine; Male; Rats; Serine; Stereoisomerism; Structure-Activity Relationship; Sulfhydryl Compounds | 1973 |
The stereochemistry of pyridoxal phosphate enzymes. The absolute stereochemistry of cofactor C' 4 protonation in the transamination of holoserine hydroxymethylase by D-alanine.
Topics: Alanine; Aldehydes; Amination; Amino Acids; Animals; Chemical Phenomena; Chemistry; Glycine; Isomerism; Liver; Phosphoric Acids; Protons; Pyridoxal Phosphate; Pyridoxamine; Pyruvates; Serine; Sheep; Tetrahydrofolates; Transaminases; Transferases; Tritium | 1973 |
Rat liver aminomalonate decarboxylase. Identity with cytoplasmic serine hydroxymethylase and allothreonine aldolase.
Topics: Alanine; Aldehyde-Lyases; Amino Acids; Animals; Binding Sites; Binding, Competitive; Carbon Isotopes; Carboxy-Lyases; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Glycine; Liver; Male; Malonates; Mitochondria, Liver; Molecular Weight; Protein Denaturation; Rats; Serine; Tetrahydrofolates; Threonine; Transferases; Tritium | 1973 |
Competitive inhibition for amino acid uptake by the indigenous microflora of Upper Klamath Lake.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacteria; Canada; Carbon Dioxide; Carbon Isotopes; Culture Media; Fresh Water; Glutamates; Glycine; Isoleucine; Leucine; Micropore Filters; Plankton; Serine; Valine; Water Microbiology | 1973 |
A growth factor for animal cells derived from peptone. I. Isolation and characterization of the growth factor.
Topics: Alanine; Aspartic Acid; Chromatography, Gel; Chromatography, Paper; Clone Cells; Culture Media; Culture Techniques; Glutamates; Glycine; Growth Substances; L Cells; Lysine; Molecular Weight; Peptones; Serine; Spectrophotometry; Threonine | 1973 |
Hyperglutamatemia in primary gout.
Topics: Adult; Aged; Alanine; Ammonia; Chromatography; Fasting; Glutamates; Glutamine; Glycine; Gout; Humans; Male; Metabolism, Inborn Errors; Middle Aged; Serine; Threonine; Uric Acid | 1973 |
Large growth hormone: evidence for the association of growth hormone with another protein moiety in the rat pituitary.
Topics: Alanine; Animals; Carbon Isotopes; Chemical Precipitation; Growth Hormone; Guanidines; In Vitro Techniques; Leucine; Lysine; Male; Pituitary Gland; Rats; Serine; Tritium | 1973 |
The reversal of triparanol-induced cataracts in the rat. 3. Amino acid content and uptake of 14 C -AIB in cataractous and clearing lenses.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Cataract; Cystine; Diet; Glutamates; Glycine; Histidine; Isoleucine; Lens, Crystalline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Serine; Threonine; Triparanol; Tyrosine; Valine | 1973 |
Modifications of serum-free amino acid patterns of Babinga adult pygmies after short-term feeding of a balanced diet.
Topics: Adolescent; Adult; Alanine; Amino Acids; Anti-Infective Agents; Black People; Central African Republic; Diet; Dietary Fats; Dietary Proteins; Feeding Behavior; Glutamates; Glycine; Humans; Intestinal Diseases; Male; Nutritional Physiological Phenomena; Phenylalanine; Protein Deficiency; Serine; Time Factors; Tyrosine; Vitamins | 1973 |
Amino acid levels in plasma, liver, and skeletal muscle during protein deprivation.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Body Weight; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Liver; Male; Methionine; Muscles; Organ Size; Phenylalanine; Protein Deficiency; Rats; Serine; Threonine; Time Factors; Tyrosine; Valine | 1973 |
Fractionation of glycine, alanine, and serine transfer ribonucleic acids from the silk gland.
Topics: Alanine; Animals; Bombyx; Chromatography; Glycine; Larva; RNA, Transfer; Serine | 1973 |
Regulation of amino acid transport in chick embryo heart cells. 3. Formal identification of the A mediation as an adaptive transport system.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Carbon Isotopes; Carboxylic Acids; Cell Membrane; Chick Embryo; Glycine; Heart; In Vitro Techniques; Kinetics; Leucine; Lysine; Methylation; Myocardium; Phenylalanine; Serine; Sodium; Time Factors | 1973 |
Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. Crystal structure determination and stereochemistry of the contact region.
Topics: Alanine; Animals; Aspartic Acid; Binding Sites; Cattle; Fourier Analysis; Glycine; Histidine; Kinetics; Lysine; Models, Structural; Pancreas; Protein Conformation; Serine; Trypsin; Trypsin Inhibitors; X-Ray Diffraction | 1973 |
Hybrid formation between collagen and synthetic polypeptides.
Topics: Alanine; Amino Acids; Animals; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Collagen; Glycine; Hybridization, Genetic; Molecular Conformation; Molecular Weight; Optical Rotation; Peptides; Proline; Protein Binding; Protein Conformation; Protein Denaturation; Rabbits; Serine; Skin; Temperature; Tropomyosin | 1973 |
The activation of prothrombin. II. Partial reactions, physical and chemical characterization of the intermediates of activation.
Topics: Alanine; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Citrates; Disulfides; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Factor X; Isoflurophate; Molecular Weight; Oxidation-Reduction; Prothrombin; Serine; Sodium Dodecyl Sulfate; Spectrophotometry; Thrombin; Tritium; Trypsin; Ultracentrifugation | 1973 |
Alterations in renal and plasma amino acid concentrations during renal compensatory growth.
Topics: Alanine; Amino Acids; Animals; Kidney; Kidney Cortex; Leucine; Male; Methionine; Nephrectomy; Ornithine; Rats; Serine; Starvation; Threonine; Tyrosine | 1973 |
Changes in the tertiary structure of alpha-chymotrypsin with change in pH: p4 4.2-6.7.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Binding Sites; Chymotrypsin; Histidine; Hydrogen-Ion Concentration; Macromolecular Substances; Methionine; Models, Structural; Phenylalanine; Protein Binding; Protein Conformation; Serine; Tyrosine; Uranium; X-Ray Diffraction | 1973 |
The synthesis of taurine from sulfate. V. Regulatory modifiers of the chick liver enzyme system.
Topics: Adenosine Monophosphate; Alanine; Allosteric Regulation; Animals; Chickens; Cysteine; Ethionine; Homocysteine; Liver; Methionine; Organophosphorus Compounds; S-Adenosylmethionine; Serine; Sulfinic Acids; Sulfonic Acids; Sulfur Radioisotopes; Sulfuric Acids; Sulfurtransferases; Taurine | 1973 |
Effect of cortisol treatment on free amino acid levels in rats.
Topics: Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Glycine; Hydrocortisone; Liver; Male; Muscle Proteins; Muscles; Proline; Rats; Serine | 1973 |
Influence of denervation on the free amino acids of the rat diaphragm.
Topics: Alanine; Amino Acids; Animals; Asparagine; Denervation; Diaphragm; Glutamine; Glycine; Liver Regeneration; Male; Rats; Serine; Taurine; Time Factors | 1973 |
Effect of anesthesia and-or hypothermia on cerebral free amino acids in young rats.
Topics: Age Factors; Alanine; Amino Acids; Aminobutyrates; Anesthesia; Animals; Animals, Newborn; Aspartic Acid; Body Temperature; Brain; Brain Chemistry; Ethanolamines; Glutamates; Glutamine; Hypothermia, Induced; Leucine; Methionine; Rats; Serine | 1973 |
Purification and properties of uridine diphosphate N-acetylmuramate: L-alanine ligase.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Carbon Radioisotopes; Cations, Monovalent; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Paper; Electrophoresis, Polyacrylamide Gel; Glycine; Hydrogen-Ion Concentration; Mercaptoethanol; Metals; Muramic Acids; Peptide Synthases; Serine; Staphylococcus; Uracil Nucleotides; Uridine Diphosphate Sugars | 1973 |
Amino acid metabolism in chameleon tissues.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brain; Citrulline; Glutamates; Glutamine; Glycine; Histidine; Ketoglutaric Acids; Kidney; Liver; Lysine; Muscles; Myocardium; Ornithine; Oxaloacetates; Proline; Pyruvates; Reptiles; Serine; Tryptophan | 1973 |
Similarities between pyruvate kinase from human placenta and tumours.
Topics: Adenosine Triphosphate; Alanine; Carcinoma; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Starch Gel; Female; Fructosephosphates; Humans; Intestinal Neoplasms; Isoenzymes; Jejunum; Kinetics; Lung Neoplasms; Male; Molecular Weight; Organ Specificity; Phenylalanine; Placenta; Pregnancy; Pyruvate Kinase; Serine; Stomach Neoplasms | 1973 |
The metabolism of amino acids in the bovine lens. Their oxidation as a source of energy.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Carbon Dioxide; Carbon Radioisotopes; Cattle; Collagen; Energy Metabolism; Glucose; Glutamates; Glutathione; In Vitro Techniques; Lactates; Lens, Crystalline; Leucine; Lipid Metabolism; Lysine; Oxidation-Reduction; Proline; Serine; Taurine; Tryptophan; Tyrosine | 1973 |
Studies on the inhibition of the L-serine O-sulphate-degrading system of pig liver and the topography of its active site.
Topics: Alanine; Animals; Binding Sites; Binding, Competitive; Esters; Iodoacetates; Kinetics; Liver; Salicylates; Serine; Structure-Activity Relationship; Sulfates; Swine | 1973 |
Kuwaitimycin, a new antibiotic.
Topics: Alanine; Animals; Anti-Bacterial Agents; Arginine; Bacteria; Crystallization; Glutamates; Hydrolysis; Lysine; Male; Serine; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Streptomyces | 1973 |
Free amino acids in E.L.4 mouse ascites tumor cells taken from susceptible (C57BL) and resistant (B10.D2) mice.
Topics: Alanine; Amino Acids; Animals; Arginine; Cell Line; Computers; Depression, Chemical; Glycine; Histidine; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Neoplasms, Experimental; Serine; Species Specificity; Time Factors; Tyrosine | 1973 |
Variations in isoaccepting species of transfer RNA during embryogenesis of Oncopeltus fasciatus (Dallas).
Topics: Acylation; Alanine; Animals; Aspartic Acid; Carbon Radioisotopes; Chromatography; Female; Insecta; Lysine; Methionine; Ovum; Protein Biosynthesis; RNA, Transfer; Serine; Tritium | 1973 |
Functional and modulatory adaptation of tRNA in the silk gland of bombyx mori L. to fibroin biosynthesis.
Topics: Alanine; Amino Acids; Animals; Bombyx; Fibroins; Genetic Code; Glycine; Metamorphosis, Biological; Protein Biosynthesis; RNA, Messenger; RNA, Transfer; Serine; Tyrosine | 1973 |
Hemoglobin Lepore Boston in two Iranian families.
Topics: Alanine; Amino Acids; Blood Protein Electrophoresis; Boston; Child; Chromatography, DEAE-Cellulose; Electrophoresis, Starch Gel; Fetal Hemoglobin; Glucosephosphate Dehydrogenase; Hemoglobins, Abnormal; Humans; Hydroxymercuribenzoates; Iran; Mercaptoethanol; Peptides; Phosphoglycerate Kinase; Serine; Thalassemia; Trypsin; Urea | 1974 |
A lysine-rich protein from spermatozoa of the mollusc Mytilus edulis.
Topics: Alanine; Amino Acids; Animals; Arginine; Bivalvia; Chromatin; Chromatography, Gel; Chromatography, Paper; Electrophoresis, Paper; Histones; Hydrogen-Ion Concentration; Lysine; Male; Molecular Weight; Peptide Fragments; Proline; Protamines; Proteins; Serine; Spermatozoa; Thiocyanates; Trypsin | 1974 |
The effect of deficiency of thiamine on the metabolism of (U-14C)glucose and (U-14C)ribose and the levels of amino acids in rat brain.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Body Weight; Brain; Carbon Radioisotopes; Chromatography, Ion Exchange; Glucose; Glutamates; Glutamine; Glycolysis; Lactates; Liver; Male; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Ribose; Serine; Thiamine Deficiency; Time Factors | 1974 |
Localization of the histidine-rich protein in keratohyalin: a morphologic and macromolecular marker in epidermal differentiation.
Topics: Alanine; Animals; Animals, Newborn; Arginine; Aspartic Acid; Cell Differentiation; Cytoplasmic Granules; Electrophoresis, Polyacrylamide Gel; Glutamates; Glycine; Histidine; Histocytochemistry; Keratins; Macromolecular Substances; Microscopy, Electron; Microscopy, Electron, Scanning; Rats; Serine; Skin; Threonine; Tritium | 1974 |
Renal metabolism of amino acids and ammonia in fed and fasted pregnant sheep.
Topics: Acidosis; Alanine; Amino Acids; Ammonia; Animals; Arginine; Aspartic Acid; Catheterization; Citrulline; Fasting; Female; Glutamates; Glutamine; Glycine; Hypoglycemia; Kidney; Pregnancy; Pregnancy, Animal; Regional Blood Flow; Renal Artery; Serine; Sheep | 1974 |
An acetylated N-terminus of adenovirus type 2 hexon protein.
Topics: Acetylation; Adenoviridae; Alanine; Amino Acid Sequence; Carbon Radioisotopes; Chromatography, Ion Exchange; Electrophoresis, Paper; Hydrogen-Ion Concentration; Mass Spectrometry; Peptide Fragments; Proline; Serine; Threonine; Time Factors; Viral Proteins | 1974 |
Mechanism of the salicylate 1-monooxygenase reaction. VI. The monomeric nature of the enzyme.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Carboxypeptidases; Electrophoresis, Polyacrylamide Gel; Fluorine; Hydrazines; Mixed Function Oxygenases; Molecular Weight; Nitrobenzenes; Oxidation-Reduction; Pseudomonas; Salicylates; Serine; Sodium Dodecyl Sulfate; Time Factors; Tritium | 1974 |
Selective malabsorption of vitamin B 12: report of a case with metabolic studies.
Topics: Alanine; Amino Acids; Anemia, Macrocytic; Child; Chromatography, Gas; Glycine; Hemoglobins; Histidine; Humans; Isoleucine; Leucine; Malabsorption Syndromes; Male; Malonates; Methionine; Proteinuria; Renal Tubular Transport, Inborn Errors; Reticulocytes; Serine; Taurine; Threonine; Tyrosine; Valine; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Intracellular free amino acid concentration in human muscle tissue.
Topics: Adult; Alanine; Amino Acids; Arginine; Asparagine; Biopsy, Needle; Body Water; Chlorides; Citrulline; Extracellular Space; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Muscles; Ornithine; Phenylalanine; Proline; Serine; Taurine; Tyrosine; Valine | 1974 |
Gluconeogenesis from serine by the serine-dehydratase-dependent pathway in rat liver.
Topics: Alanine; Animals; Avidin; Biotin; Carbon Radioisotopes; Diet; Fasting; Fructose; Gluconeogenesis; Glucose; Glyceric Acids; L-Serine Dehydratase; Liver; Male; Perfusion; Pyruvate Carboxylase; Pyruvates; Rats; Serine; Transaminases; Vitamin B Deficiency | 1974 |
Hyperglutamatemia in primary gout.
Topics: Administration, Oral; Alanine; Erythrocytes; Glutamates; Glutamine; Glycine; Gout; Humans; Male; Puberty; Serine; Threonine; Time Factors; Uric Acid | 1974 |
Interorganal relationships of amino acid metabolism in fed rats.
Topics: Alanine; Amino Acids; Animals; Caseins; Diet; Dietary Proteins; Fasting; Glutamine; Glycine; Kidney; Liver; Liver Circulation; Male; Nitrogen; Rats; Renal Artery; Renal Veins; Serine | 1974 |
[Synthesis routes of the principal amino acids of silk in the silk gland of the silkworm].
Topics: Alanine; Alanine Transaminase; Aldehyde-Lyases; Amino Acids; Aspartate Aminotransferases; Bombyx; Carboxy-Lyases; Electrophoresis, Polyacrylamide Gel; Fibroins; Glycine; Serine; Transferases; Tyrosine | 1974 |
The complete amino acid sequence of alanine apolipoprotein (apoC-3), and apolipoprotein from human plasma very low density lipoproteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Apoproteins; Chromatography, Gas; Chromatography, Thin Layer; Galactosamine; Galactose; Humans; Hyperlipidemias; Lipoproteins; Neuraminic Acids; Serine; Succinates; Thiocyanates; Time Factors; Trypsin | 1974 |
Codon responses of tRNA-Ala, tRNA-Gly and tRNA-Ser from the posterior part of the silkgland of Bombyx mori L.
Topics: Alanine; Animals; Binding Sites; Bombyx; Chromatography, DEAE-Cellulose; Countercurrent Distribution; Genetic Code; Glycine; Micrococcus; Polyribonucleotide Nucleotidyltransferase; Protein Binding; Ribonucleotides; Ribosomes; RNA, Messenger; RNA, Transfer; Serine; Spectrophotometry, Ultraviolet; Tritium | 1974 |
Mechanism of action of naturally occurring proteinase inhibitors. Studies with anhydrotrypsin and anhydrochymotrypsin purified by affinity chromatography.
Topics: Alanine; Binding Sites; Binding, Competitive; Borohydrides; Carbon Radioisotopes; Chromatography, Affinity; Chymotrypsin; Circular Dichroism; Egg Proteins; Glycine max; Hydrogen-Ion Concentration; Hydrolysis; Mucoproteins; Oxidation-Reduction; Pancreas; Plants; Protein Denaturation; Serine; Spectrophotometry, Ultraviolet; Tritium; Trypsin; Trypsin Inhibitors | 1974 |
Altered amino acid concentrations accompanying suppression of malignancy of mouse melanoma cells by 5-bromodeoxyuridine.
Topics: Alanine; Amino Acids; Animals; Asparagine; Bromodeoxyuridine; Cells, Cultured; Glutamates; Glutamine; Glycine; Lysine; Melanoma; Methionine; Mice; Neoplasm Proteins; Ornithine; Phenylalanine; Pigmentation; Proline; Serine; Threonine; Valine | 1974 |
A simple method for large-scale preparation of chick embryo tRNA.
Topics: Alanine; Animals; Asparagine; Carbon Radioisotopes; Chick Embryo; Chromatography, DEAE-Cellulose; Chromatography, Gel; Evaluation Studies as Topic; Glycine; Hydrogen-Ion Concentration; Methods; RNA, Transfer; Serine; Threonine; Time Factors; Valine | 1974 |
sRNA specificity for codon recognition as studied by the ribosomal binding technique.
Topics: Alanine; Arginine; Chromatography; Countercurrent Distribution; Escherichia coli; Genetic Code; Glycine; Isoleucine; Leucine; Methionine; Phenylalanine; Polynucleotides; Ribosomes; RNA, Transfer; Serine; Tryptophan; Valine; Yeasts | 1966 |
Glycine uptake in Escherichia coli. II. Glycine uptake, exchange, and metabolism by an isolated membrane preparation.
Topics: Alanine; Arsenic; Autoradiography; Azides; Biological Transport; Carbon Isotopes; Cell Membrane; Chromatography, Thin Layer; Cold Temperature; Cyanides; Dinitrophenols; Escherichia coli; Glucose; Glycine; Helium; Hydrazines; Hydrogen-Ion Concentration; Hydroxylamines; Iodoacetates; Magnesium; Mercury; Nucleotides; Phosphatidylethanolamines; Serine; Sulfonic Acids; Threonine | 1968 |
[Study of antibacterial properties of alpha-alkylserines and 4-alkyl substituted derivatives of cycloserine].
Topics: Alanine; Alkylation; Anti-Bacterial Agents; Bacteria; Cycloserine; Escherichia coli; Leucine; Mycobacterium; Serine; Staphylococcus | 1968 |
Amino acid transport systems in Escherichia coli K-12.
Topics: Alanine; Amino Acids; Azides; Biological Transport; Calcium; Carbon Isotopes; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Kinetics; Leucine; Methionine; Phenylalanine; Serine; Sodium; Temperature; Tryptophan; Tyrosine; Valine | 1968 |
The complete amino acid sequence of the acyl carrier protein of Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Arginine; Bacterial Proteins; Bromides; Chromatography, Ion Exchange; Cyanides; Cyclohexanes; Escherichia coli; Pepsin A; Serine; Trypsin | 1968 |
Effect of aliphatic amino acids and citric acid cycle compounds on early thiamine production by thiazoleless mutant of Escherichia coli.
Topics: Alanine; Amino Acids; Ammonium Chloride; Aspartic Acid; Carbon Isotopes; Culture Media; Dicarboxylic Acids; Escherichia coli; Formates; Fumarates; Glucose; Glutamates; Lysine; Malates; Mutation; Pyruvates; Serine; Succinates; Thiamine; Thiazoles; Valine | 1968 |
Suppressor selectrion for amino acid replacements expected on the basis of the genetic code.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bacterial Proteins; Escherichia coli; Genes; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Histidine; Hydro-Lyases; Isoleucine; Leucine; Lysine; Methionine; Mutation; Nucleotides; Phenylalanine; RNA, Messenger; Serine; Suppression, Genetic; Threonine; Tyrosine; Valine | 1967 |
[Soluble ribonucleic acid from sheep mammary gland. II. Acceptor power].
Topics: Adenosine Triphosphate; Alanine; Animals; Arginine; Carbon Isotopes; Chromatography, Gel; Escherichia coli; Female; Glutathione; Hydrogen-Ion Concentration; Kinetics; Leucine; Ligases; Liver; Magnesium; Mammary Glands, Animal; Rabbits; RNA, Transfer; Serine; Sheep; Valine | 1969 |
Tyrosine phenol lyase. I. Purification, crystallization, and properties.
Topics: Alanine; Amino Acids; Ammonia; Catechols; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Culture Media; Cysteine; Electrophoresis; Escherichia coli; Feedback; Kinetics; Lyases; Methods; Molecular Weight; Phenols; Protamines; Pyridoxal Phosphate; Pyruvates; Quaternary Ammonium Compounds; Serine; Stereoisomerism; Sulfates; Tyrosine; Ultracentrifugation | 1970 |
The two site model of ribosomal function: a test using degenerate serine codons in bacteriophage f2 mRNA.
Topics: Alanine; Bacteriophages; Countercurrent Distribution; DNA Nucleotidyltransferases; Electrophoresis; Escherichia coli; Genetic Code; Models, Biological; Nucleotides; Ribosomes; RNA, Messenger; RNA, Transfer; Serine; Tritium; Viral Proteins | 1970 |
Plasmolysis and bacterial motility: a method for the study of membrane function.
Topics: Alanine; Bacteria; Bacteriological Techniques; Buffers; Cell Membrane; Centrifugation; Culture Media; Filtration; Flagella; Hypertonic Solutions; Microscopy, Electron; Movement; Nitrates; Osmosis; Oxygen Consumption; Potassium; Serine; Stereoisomerism; Sucrose | 1969 |
Substrate specificity of ribosomal peptidyl transferase. The effect of the nature of the amino acid side chain on the acceptor activity of 2'(3')-O-aminoacyladenosines.
Topics: Acetates; Acyltransferases; Alanine; Amino Acids; Binding Sites; Carbon Isotopes; Escherichia coli; Glutamine; Glycine; Imidazoles; Leucine; Lysine; Methionine; Nucleosides; Peptides; Phenylalanine; Proline; Ribosomes; RNA, Transfer; Serine; Stereoisomerism; Valine | 1970 |
Additive Edman degradation to sequence small peptides.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Chromatography, Gas; Hydantoins; Methods; Peptides; Phenylalanine; Serine; Silicones; Thiazoles; Valine | 1971 |
NH2-terminal methionine in nascent peptides from Neurospora crassa.
Topics: Alanine; Carbon Isotopes; Escherichia coli; Glycine; Methionine; Neurospora; Peptide Biosynthesis; Protein Biosynthesis; Puromycin; Ribosomes; Serine | 1971 |
Hypothesis for catabolite repression.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Escherichia coli; Genes, Regulator; Genetic Code; Methionine; Models, Biological; Operon; RNA, Bacterial; Serine | 1971 |
The primary structure of transfer ribonucleic acid.
Topics: Alanine; Aspartic Acid; Cryptococcus; Escherichia coli; Genetic Code; Isoleucine; Leucine; Methionine; Methylation; Nucleotides; Phenylalanine; RNA, Transfer; Saccharomyces; Serine; Tryptophan; Tyrosine; Valine | 1971 |
The effect of branched chain amino acids on the synthesis of isoleucine from threonine and pyruvate in crude extracts from Escherichia coli.
Topics: Alanine; Aspartic Acid; Chromatography, Thin Layer; Escherichia coli; Isoleucine; Leucine; Pyruvates; Serine; Threonine; Tissue Extracts; Valine | 1970 |
Induction of pigmentation in nonproliferating cells of Serratia marcescens by addition of single amino acids.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Aspartic Acid; Bacteriological Techniques; Caseins; Culture Media; Filtration; Glutamates; Ornithine; Pigments, Biological; Prodigiosin; Proline; Protein Hydrolysates; Pyrroles; Serine; Serratia marcescens; Stereoisomerism; Temperature | 1971 |
Effect of serine hydroxamate on the growth of Escherichia coli.
Topics: Adenine; Alanine; Amino Acids; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Densitometry; Escherichia coli; Filtration; Glycine; Hydroxamic Acids; Indicators and Reagents; Serine; Spectrophotometry; Stereoisomerism; Tritium | 1971 |
[A new method of identification of Shigela cultures].
Topics: Alanine; Ammonia; Bacteriological Techniques; Culture Media; Deamination; Enterobacteriaceae; Glycine; Phenolphthaleins; Serine; Shigella; Stereoisomerism | 1968 |
Regulation of tryptophanase formation in Escherichia coli.
Topics: Alanine; Amino Acids; Culture Media; Cysteine; Enzyme Activation; Escherichia coli; Glycine; Homoserine; Lysine; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phenylalanine; Proteins; Serine; Time Factors | 1971 |
Serine metabolism in the culture form of Trypanosoma cruzi: synthesis of other amino acids.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Ion Exchange; Cysteine; Glutamates; Glycine; Protein Biosynthesis; Proteins; Serine; Threonine; Trypanosoma cruzi | 1971 |
The B protein of Escherichia coli tryptophan synthetase. II. New -elimination and -replacement reactions.
Topics: Alanine; Carbon Isotopes; Chemical Phenomena; Chemistry; Chlorine; Cysteine; Escherichia coli; Ethers; Glycerophosphates; Hydro-Lyases; Indoles; Kinetics; Mercaptoethanol; Methanol; Models, Biological; Serine; Sulfhydryl Compounds; Sulfides; Tryptophan | 1971 |
D-Alanine-D-glutamate transaminase. I. Purification and characterization.
Topics: Alanine; Aminobutyrates; Apatites; Asparagine; Aspartic Acid; Bacillus subtilis; Chemical Phenomena; Chemistry; Chromatography; Dextrans; Electrophoresis; Glutamates; In Vitro Techniques; Methionine; Ornithine; Pyridoxine; Serine; Transaminases; Ultracentrifugation | 1965 |
Enzymatic formation of beta-cyanoalanine from cyanide.
Topics: Adenosine Triphosphate; Alanine; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Cyanides; Cysteine; Edetic Acid; Hydroxylamines; Indicators and Reagents; Isoniazid; Magnesium; Mercury; Plants; Pyridoxal Phosphate; Semicarbazides; Serine | 1965 |
Stimulation of L-alanine-induced germination of Bacillus cereus spores by D-cycloserine and O-carbamyl-D-serine.
Topics: Alanine; Bacillus cereus; Cycloserine; Hot Temperature; Serine; Spores | 1966 |
Amino acid content of monkey brain. IV. Effects of chlorpromazine on some amino acids of certain regions of monkey brain.
Topics: Alanine; Amino Acids; Aminobutyrates; Amygdala; Animals; Aspartic Acid; Cerebellum; Chlorpromazine; Chromatography, Paper; Cystine; Female; Frontal Lobe; Glutamine; Glycine; Haplorhini; Hippocampus; Hypothalamus; Male; Mesencephalon; Reserpine; Serine | 1967 |
Amino-acid protection of ultra-violet-irradiated Bacillus subtilis.
Topics: Acid-Base Equilibrium; Alanine; Bacillus subtilis; Culture Media; Glycine; Histidine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays | 1966 |
Studies on the specificity of Bacillus subtilis neutral protease with synthetic substrates.
Topics: Alanine; Amino Acid Sequence; Bacillus subtilis; Catalysis; Histidine; Isoleucine; Kinetics; Leucine; Peptide Hydrolases; Peptides; Phenylalanine; Serine; Threonine; Valine | 1967 |
The NH2-terminal residues of Bacillus subtilis proteins.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus subtilis; Carbon Isotopes; Chromatography, Gel; Escherichia coli; Fluorine; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Nitrobenzenes; Proteins; Ribosomes; Serine; Species Specificity; Threonine; Tritium; Valine | 1968 |
Species differences of serum amino acid beta-napthylamidases.
Topics: Alanine; Amides; Amino Acids; Aminopeptidases; Animals; Arginine; Chickens; Cyprinidae; Dipeptides; Dogs; Female; Glutamine; Glycine; Haplorhini; Humans; Isoleucine; Leucine; Lysine; Methionine; Mice; Naphthalenes; Phenylalanine; Proline; Rats; Serine; Species Specificity; Valine | 1968 |
"Dysgonic" strains of mycobacterium tuberculosis on Ogawa's egg medium isolated as pathogens from patients suffering from lung tuberculosis. II. Growth-inhibitory effects of D-asparagine, D-aspartic acid, Dl-serine, or L-serine against "dysgonic".
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Culture Media; Depression, Chemical; Glutamine; Histidine; Humans; Leucine; Mycobacterium tuberculosis; Proline; Serine; Tuberculosis, Pulmonary; Valine | 1967 |
Studies on the action of O-carbamyl-D-serine in Bacillus subtilis.
Topics: Alanine; Amino Acids; Bacillus subtilis; Carbamates; Cell Wall; Centrifugation; Chromatography, Gas; Culture Media; Nucleotides; Peptides; Serine; Spectrum Analysis; Ultraviolet Rays | 1968 |
Limitations of the initiation of germination of bacterial spores as a spore control procedure.
Topics: Alanine; Aminobutyrates; Bacillus; Bacillus cereus; Culture Media; Food Microbiology; Glucose; Isomerases; Nucleosides; Serine; Spores | 1968 |
Bacillus cereus spore germination:absolute requirement for an amine acid.
Topics: Alanine; Amino Acids; Aminobutyrates; Bacillus cereus; Culture Media; Glycine; Hot Temperature; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Nucleosides; Purines; Serine; Spores; Stereoisomerism; Valine | 1968 |
On the C-terminal amino acid of bacterial alpha-amylase.
Topics: Alanine; Amino Acid Sequence; Amylases; Aspartic Acid; Bacillus subtilis; Carbon; Chemical Phenomena; Chemistry; Electrophoresis; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Paper; Serine; Threonine; Tyrosine; Valine | 1968 |
Serine-containing active center of alkaline proteinase of Aspergillus flavus.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Arthrobacter; Aspergillus; Bacillus subtilis; Binding Sites; Chromatography, Ion Exchange; Chromatography, Paper; Glycine; Isoflurophate; Methionine; Peptide Hydrolases; Phosphorus Isotopes; Serine; Streptomyces; Threonine; Trypsin | 1969 |
The amino-terminal residues of Bacillus subtilis proteins made in vitro.
Topics: Alanine; Bacillus subtilis; Bacterial Proteins; Carbon Isotopes; Cell-Free System; Chromatography, Gel; Folic Acid; Formates; Kinetics; Methionine; Molecular Weight; Peptide Biosynthesis; Peptide Hydrolases; RNA, Messenger; Serine; Threonine; Tritium; Valine | 1970 |
Effect of O-carbamyl-D-serine on the growth of mycobacterium tuberculosis.
Topics: Alanine; Amino Acids; Amino Sugars; Binding Sites; Carbamates; Culture Media; Cycloserine; Drug Synergism; Ligases; Mycobacterium tuberculosis; Receptors, Drug; Serine | 1970 |
Plasma amino acid levels in diabetic ketoacidosis.
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Arginine; Butyrates; Child; Citrulline; Cystine; Diabetic Ketoacidosis; Female; Glycine; Histidine; Humans; Insulin; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1970 |
The amino acid neighbors of thyroxine in thyroglobulin.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Female; Gels; Glutamates; Iodine Isotopes; Monoiodotyrosine; Peptides; Rabbits; Serine; Thyroglobulin; Thyroid Gland; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine; Ultracentrifugation | 1970 |
The isolation of gamma-glutamyl peptides from monkey brain.
Topics: Alanine; Animals; Brain Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Glutamates; Glutamine; Glycine; Haplorhini; Isoleucine; Peptides; Serine; Species Specificity; Valine | 1970 |
Resistance to D-cycloserine in the tubercle bacilli: mutation rate and transport of alanine in parental cells and drug-resistant mutants.
Topics: Alanine; Carbamates; Carbon Isotopes; Cycloserine; Drug Resistance, Microbial; Genetics, Microbial; Glycine; Membrane Transport Proteins; Mutation; Mycobacterium tuberculosis; Serine | 1971 |
[Nitrogen metabolism in parenteral feeding].
Topics: Adult; Aged; Alanine; Amino Acids; Ammonia; Creatinine; Diet Therapy; Duodenal Ulcer; Female; Glycine; Humans; Male; Methionine; Middle Aged; Nitrogen; Parenteral Nutrition; Proline; Serine; Stomach Ulcer; Tryptophan; Urea | 1971 |
Properties and subunit structure of the B component of Pseudomonas putida tryptophan synthetase.
Topics: Alanine; Amino Acids; Borohydrides; Carboxypeptidases; Catalysis; Chemical Precipitation; Chromatography, Gel; Cross Reactions; Detergents; Drug Stability; Electrophoresis, Disc; Escherichia coli; Formates; Glycerophosphates; Hot Temperature; Hydro-Lyases; Immune Sera; Immunodiffusion; Indoles; Kinetics; Macromolecular Substances; Mercaptoethanol; Molecular Weight; Oxidation-Reduction; Pseudomonas; Pyridoxal Phosphate; Serine; Spectrophotometry; Sulfuric Acids; Tryptophan; Ultracentrifugation; Urea | 1971 |
Formation of -cyanoalanine by O-acetylserine sulfhydrylase.
Topics: Acetates; Alanine; Ammonium Sulfate; Bacillus megaterium; Carbon Isotopes; Cell-Free System; Chemical Precipitation; Chromatography, DEAE-Cellulose; Colorimetry; Culture Media; Cyanides; Cysteine; Lyases; Protamines; Serine; Sulfates | 1971 |
Biosynthesis of bacterial menaquinones (vitamins K 2 ).
Topics: Acetates; Acylation; Alanine; Benzoates; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Thin Layer; Corynebacterium diphtheriae; Decarboxylation; Escherichia coli; Glucose; Glutamates; Keto Acids; Ketoglutaric Acids; Malonates; Mass Spectrometry; Models, Biological; Mycobacterium; Naphthalenes; Naphthoquinones; Oxidation-Reduction; Phenylacetates; Phenylalanine; Phthalic Acids; Pyruvates; Ribose; Serine; Shikimic Acid; Streptomyces; Vitamin K | 1971 |
Serine biosynthesis in Tetrahymena pyriformis S.
Topics: Acetates; Acyltransferases; Alanine; Aldehyde-Lyases; Animals; Carbon Isotopes; Citric Acid Cycle; Fatty Acids; Formates; Glucose; Glutamates; Glycine; Ketoglutaric Acids; Lactates; Protein Biosynthesis; Pyruvates; Serine; Tetrahymena pyriformis; Threonine | 1971 |
The effect of strychnine and of electrical stimulation on the labelling of -aminobutyric acid and other free amino acids from (U- 14 C)glucose in the spinal cord of the nembutalized rat.
Topics: Alanine; Amino Acids; Aminobutyrates; Anesthesia; Animals; Aspartic Acid; Carbon Isotopes; Electric Stimulation; Glucose; Glutamates; Glutamine; Glycine; Male; Pentobarbital; Rats; Serine; Spinal Cord; Strychnine | 1972 |
Incorporation of carbon from glucose into cerebral amino acids, proteins and lipids, and alterations during recovery from hypoglycaemia.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Blood Glucose; Carbon Isotopes; Cerebral Cortex; Cerebrosides; Cholesterol; Dogs; Electroencephalography; Gangliosides; Glucose; Glutamates; Glutamine; Hypoglycemia; Insulin; Lipid Metabolism; Male; Nerve Tissue Proteins; Phosphatidylethanolamines; Seizures; Serine | 1972 |
The effect of diethyl- -fluoroglutarate on phosphates and glutamate in slices of rabbit cerebral cortex.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Cerebral Cortex; Esters; Fluorine; Glucose; Glutamate Dehydrogenase; Glutamates; Glutamine; Glutarates; Glycine; Oxidative Phosphorylation; Phosphates; Rabbits; Serine; Threonine | 1972 |
The effect of topical application of diethyl- -fluoroglutarate on the metabolism and electrical activity in vivo of cat cerebral cortex.
Topics: Adenosine Triphosphate; Alanine; Aminobutyrates; Ammonia; Animals; Aspartic Acid; Cats; Cerebral Cortex; Electric Stimulation; Electroencephalography; Esters; Fluorine; Glucose; Glucosephosphates; Glutamates; Glutamine; Glutarates; Glycine; Lactates; Malates; Pyruvates; Serine; Synapses; Thalamic Nuclei; Threonine | 1972 |
Isolation and identification of the messenger RNA for silk fibroin from Bombyx mori.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Bombyx; Centrifugation, Density Gradient; Cytosine; Electrophoresis; Fibroins; Genetic Code; Glycine; Phosphorus Isotopes; Polynucleotides; RNA, Messenger; Serine | 1972 |
The purification and characterization of a novel peptidase from sheep red cells.
Topics: Alanine; Ammonium Sulfate; Animals; Chromatography, DEAE-Cellulose; Dipeptides; Electrophoresis; Endopeptidases; Erythrocytes; Glycine; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Methionine; Molecular Weight; Peptides; Protease Inhibitors; Reticulocytes; Serine; Sheep | 1972 |
Amino acid metabolism during starvation in human pregnancy.
Topics: Adolescent; Adult; Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Blood Glucose; Female; Food Deprivation; Gluconeogenesis; Glycine; Humans; Hypoglycemia; Isoleucine; Leucine; Pregnancy; Serine; Starvation; Threonine; Time Factors; Valine | 1972 |
Condition of cell-wall mucopeptide in dividing and non-dividing cells of Micrococcus lysodeikticus dis-IIp + .
Topics: Alanine; Amino Acids; Amino Sugars; Carbon Isotopes; Cell Division; Cell Wall; Chromatography, Thin Layer; Cycloserine; Histocytochemistry; Hydroxylamines; Lactones; Micrococcus; Microscopy, Electron; Mitomycins; Penicillins; Peptide Biosynthesis; Peptides; Serine; Spermine; Stereoisomerism; Vancomycin | 1972 |
The synthesis of taurine from sulfate. 3. Further evidence for the enzymatic pathway in chick liver.
Topics: Adenine Nucleotides; Alanine; Animals; Carbon Isotopes; Carboxy-Lyases; Chickens; Chromatography, Ion Exchange; L-Serine Dehydratase; Liver; Pyridoxal Phosphate; Serine; Sulfates; Sulfonic Acids; Sulfurtransferases; Taurine | 1972 |
Concentration gradients of amino acids between the uterine and blastocoelic fluid in the rabbit.
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Body Fluids; Female; Glutamates; Glycine; Male; Methionine; Methods; Ovum; Pregnancy; Rabbits; Serine; Taurine; Uterus | 1972 |
The aminoaciduria of pregnancy.
Topics: Alanine; Amino Acids; Female; Folic Acid; Glycine; Histidine; Humans; Kidney; Pregnancy; Renal Aminoacidurias; Serine; Statistics as Topic; Threonine | 1972 |
Urinary aminograms in normal infants and children.
Topics: Adolescent; Alanine; Child; Child, Preschool; Glutamates; Glycine; Histidine; Humans; Infant; Infant, Newborn; Renal Aminoacidurias; Serine; Taurine; Tyrosine | 1972 |
The difference in the availabilities of initiation points of phage RNA cistrons in their translation.
Topics: Alanine; Arginine; Carbon Isotopes; Chromatography; Coliphages; Genetic Code; Genetics, Microbial; Leucine; Phenylalanine; Ribosomes; RNA, Transfer; RNA, Viral; Serine; Viral Proteins | 1972 |
Characterization of three sequential polydipeptides containing glycine.
Topics: Alanine; Amino Acid Sequence; Circular Dichroism; Glutamine; Glycine; Infrared Rays; Microscopy, Electron; Molecular Weight; Peptides; Protein Conformation; Serine; Spectrum Analysis; X-Ray Diffraction | 1972 |
Enzymatic synthesis of D-alanyl-D-alanine. Two binding modes for product on D-alanine: D-alanine ligase (ADP).
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Cycloserine; Dipeptides; Drug Stability; Hot Temperature; Ligases; Magnesium; Manganese; Phosphorus Isotopes; Protein Binding; Serine; Valine | 1972 |
Net metabolism of plasma amino acids by liver and portal-drained viscera of fed sheep.
Topics: Alanine; Amino Acids; Ammonia; Animal Feed; Animals; Arginine; Aspartic Acid; Blood Flow Velocity; Dietary Proteins; Digestive System; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Liver; Liver Circulation; Nitrogen; Ornithine; Phenylalanine; Serine; Sheep; Tyrosine; Valine | 1972 |
Metabolism and interconversions of five plasma amino acids by tissues of the sheep.
Topics: Alanine; Amino Acids; Animal Feed; Animals; Aspartic Acid; Blood Flow Velocity; Carbon Isotopes; Dietary Proteins; Digestive System; Glutamates; Glycine; Hepatic Veins; Liver; Medicago sativa; Portal Vein; Serine; Sheep | 1972 |
Gluconeogenesis from plasma amino acids in fed sheep.
Topics: Alanine; Amino Acids; Animal Feed; Animals; Aorta; Aspartic Acid; Carbon Isotopes; Gluconeogenesis; Glucose; Glutamates; Glycine; Liver; Medicago sativa; Portal Vein; Serine; Sheep | 1972 |
Amino acids in amniotic fluid: changes in concentrations during the first half of pregnancy.
Topics: Abortion, Therapeutic; Adult; Alanine; Amino Acids; Amniotic Fluid; Arginine; Chromatography, Ion Exchange; Female; Gestational Age; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Serine; Tyrosine; Valine | 1972 |
Amino acid patterns in the blood plasma of the young bovine.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Cystine; Female; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1972 |
Influence of nutrition on the morphology of a strain of Bifidobacterium bifidum.
Topics: Acetates; Alanine; Amino Acids; Asparagine; Aspartic Acid; Culture Media; Cysteine; Glutamates; Lactobacillus; Mutation; Nutritional Physiological Phenomena; Quaternary Ammonium Compounds; Serine; Surface-Active Agents; Tryptophan | 1972 |
Effects of amino acid compounds injected into cerebrospinal fluid spaces, on colonic temperature, arterial blood pressure and behaviour of the rat.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Apnea; Behavior, Animal; Blood Pressure; Body Temperature; Body Temperature Regulation; Cerebral Ventricles; Cisterna Magna; Colon; Ethyl Ethers; Female; Glycine; Hypotension; Hypothermia; Rats; Reflex; Serine; Stereoisomerism; Taurine | 1972 |
On the role of the 4-6 N-terminal sequence in the ribonuclease S-peptide and S-protein association.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Binding Sites; Catalysis; Cattle; Guanidines; Ornithine; Pancreas; Peptides; Protein Binding; Ribonucleases; Serine | 1972 |
Endocrine control of free amino acids content in uterine fluid in pregnant rabbits.
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Body Fluids; Castration; Corpus Luteum; Embryo Implantation; Estradiol; Female; Glycine; Ovary; Pregnancy; Progesterone; Rabbits; Serine; Taurine; Threonine; Uterus | 1972 |
[Amino acid sequence of the threonine containing mureins of some species of Streptococcus].
Topics: Alanine; Amino Acid Sequence; Cell Wall; Chromatography, Paper; Chromatography, Thin Layer; Glycine; Peptidoglycan; Phosphates; Serine; Streptococcus; Threonine | 1972 |
The role of alanine and serine in hepatic gluconeogenesis.
Topics: Alanine; Amino Acids; Animals; Blood Glucose; Carbon Isotopes; Gluconeogenesis; Liver; Nephrectomy; Rats; Serine | 1972 |
Cystathionine -synthase. Studies of hydrogen exchange reactions.
Topics: Alanine; Aminobutyrates; Catalysis; Chemical Phenomena; Chemistry; Cystathionine; Cysteine; Deuterium; Homoserine; Kinetics; Lyases; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Salmonella; Serine; Succinates; Tritium | 1972 |
Gluconeogenesis and amino acid metabolism. I. Comparison of various precursors for hepatic gluconeogenesis in vivo.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood Glucose; Carbon Isotopes; Cattle; Gluconeogenesis; Glucose Oxidase; Glutamate Dehydrogenase; Glutamates; Glycerol; Glycine; Hexokinase; Histidine; Kinetics; L-Lactate Dehydrogenase; Liver; Male; Rabbits; Rats; Serine; Swine | 1972 |
Influx of neutral amino acids across the brush border of rabbit ileum. Stereospecificity and the roles of the -amino and -carboxylate groups.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Chemical Phenomena; Chemistry; Diffusion; Female; Histidine; Ileum; Intestinal Mucosa; Kinetics; Leucine; Male; Phenylalanine; Rabbits; Serine; Sodium; Stereoisomerism; Structure-Activity Relationship; Tryptophan; Valine | 1972 |
Haemoglobin Denmark Hill 95 (G2) Pro-Ala, a variant with unusual electrophoretic and oxygen-binding properties.
Topics: Adult; Alanine; Amino Acid Sequence; Amino Acids; Electrophoresis, Paper; Electrophoresis, Starch Gel; Female; Gestational Age; Hemoglobinopathies; Hemoglobins; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Leucine; London; Molecular Biology; Mutation; Oxygen; Peptides; Pregnancy; Proline; Protein Binding; Serine | 1972 |
[Comparative studies on the influence of quinolinic acid on L-serine and L-alanine metabolism in the isolated perfused rat liver].
Topics: Alanine; Animals; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Gluconeogenesis; Glucose; In Vitro Techniques; Liver; Male; Perfusion; Quinolines; Rats; Serine; Urea | 1972 |
[Beef brain alkaline phosphatase: role of magnesium on the action of L-phenylalanine and other amino acids].
Topics: Alanine; Alkaline Phosphatase; Amino Acids; Aminocaproates; Animals; Binding Sites; Brain; Cattle; Chemical Phenomena; Chemistry; Enzyme Activation; Female; Humans; Hydrogen-Ion Concentration; Intestines; Isoleucine; Kinetics; Leucine; Magnesium; Molecular Weight; Phenylalanine; Placenta; Pregnancy; Serine; Stereoisomerism; Tryptophan | 1971 |
NH 2 -terminal residues of Neurospora crassa proteins.
Topics: Alanine; Amino Acids; Autoanalysis; Cell-Free System; Chromatography, Paper; Culture Media; Dinitrophenols; Glycine; Hydrolysis; Neurospora; Phenylalanine; Proteins; Serine; Spectrophotometry | 1971 |
Effect of excess levels of individual amino acids on growth of rats fed casein diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Caseins; Cystine; Depression, Chemical; Dietary Proteins; DNA; Glutamates; Glycine; Growth; Histidine; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Organ Size; Phenylalanine; Proline; Proteins; Rats; RNA; Serine; Stereoisomerism; Stimulation, Chemical; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Effect of dietary protein level on plasma free amino acids in the chicken.
Topics: Alanine; Amino Acids; Animals; Blood; Body Weight; Caseins; Chickens; Depression, Chemical; Dietary Proteins; Glycine; Isoleucine; Leucine; Lysine; Male; Methionine; Proline; Proteins; Serine; Stimulation, Chemical; Threonine; Tyrosine; Valine | 1971 |
Quantitative changes in plasma amino acids induced by oral contraceptives.
Topics: Adult; Alanine; Amino Acids; Contraceptives, Oral; Female; Glutamine; Glycine; Gonadal Steroid Hormones; Humans; Isoleucine; Leucine; Ornithine; Ovulation; Proline; Serine; Tyrosine; Valine | 1971 |
Quantitative amino acids in amniotic fluid and maternal plasma in early and late pregnancy. Preliminary report.
Topics: Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Arginine; Aspartic Acid; Citrulline; Cystine; Female; Gestational Age; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Quantitative protein sequencing using mass spectrometry: mass spectral analysis of 2-anilino-5-thiazolinone derivatives of amino acids without prior conversion to the phenyl thiohydantoins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aniline Compounds; Animals; Arginine; Autoanalysis; Cattle; Chemical Phenomena; Chemistry; Drug Stability; Glutamates; Hydantoins; Lysine; Mass Spectrometry; Methods; Phenylalanine; Ribonucleases; Serine; Sulfides; Thiazoles; Thiocyanates; Threonine; Tyrosine | 1971 |
Daily variations in the concentrations of individual amino acids in rat plasma.
Topics: Alanine; Amino Acids; Animals; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Phenylalanine; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Reaction of 2-hydroxy-5-nitrobenzylated carboxypeptidase A with 14 C-1-fluoro-2,4-dinitrobenzene.
Topics: Alanine; Alkylation; Amino Acids; Aspartic Acid; Benzyl Compounds; Carbon Isotopes; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Thin Layer; Dinitrophenols; Fluorine; Fluorometry; Guanidines; Hydrolysis; Nitrobenzenes; Nitrophenols; Protein Denaturation; Serine; Spectrophotometry; Tryptophan; Ultraviolet Rays | 1971 |
The effect of dietary fluoride on plasma free amino acid concentrations in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Diet; Feeding Behavior; Female; Fluorides; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Rats, Inbred Strains; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Studies on the biosynthesis of mitomycin C by Streptomyces verticillatus.
Topics: Acetamides; Acetates; Alanine; Anhydrides; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Formates; Glucose; Glycine; Heptoses; Isoleucine; Leucine; Methionine; Mevalonic Acid; Mitomycins; Models, Biological; Models, Structural; Oxidation-Reduction; Pentosephosphates; Phenylalanine; Serine; Shikimic Acid; Sodium; Spectrophotometry; Streptomyces; Tryptophan; Valine | 1971 |
Specificity and some other properties of liver serine sulphhydrase: evidence for its identity with cystathionine -synthase.
Topics: Acetates; Alanine; Amino Acids; Animals; Catalysis; Chickens; Chlorine; Chromatography, Gel; Chromatography, Paper; Cycloserine; Cysteamine; Cysteine; Electrophoresis, Paper; Glycolates; Homocysteine; Hydro-Lyases; Hydroxylamines; Isoelectric Focusing; Kinetics; L-Serine Dehydratase; Liver; Mercaptoethanol; Nitriles; Penicillamine; Propionates; Pyridoxal Phosphate; Rats; Serine; Species Specificity; Sulfhydryl Compounds; Sulfides; Sulfuric Acids; Thioglycolates | 1971 |
Effect of substrate structure on coupling ratio for Na + -dependent transport of amino acids.
Topics: Alanine; Amino Acids; Animals; Asparagine; Biological Transport; Carbon Isotopes; Columbidae; Cysteine; Erythrocytes; Hydroxyproline; Kinetics; Models, Biological; Models, Structural; Potassium; Potassium Isotopes; Proline; Serine; Sodium; Sodium Chloride; Sodium Isotopes; Structure-Activity Relationship; Threonine; Tritium | 1971 |
The effect of vitamin C depletion on the free amino acid content in blood plasma of the guinea pig.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Ascorbic Acid Deficiency; Aspartic Acid; Citrulline; Cysteine; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Time Factors; Tyrosine; Valine | 1971 |
Carbohydrate metabolism in pregnancy. IX. Plasma levels of gluconeogenic fuels during fasting in the rat.
Topics: Alanine; Amino Acids; Animals; Carbohydrate Metabolism; Fasting; Female; Gluconeogenesis; Glutamates; Glutamine; Glycerol; Hypoglycemia; Lactates; Pregnancy; Pyruvates; Rats; Serine; Threonine; Time Factors | 1971 |
Correction of COOH-terminal amino acids of human plasma very low density apolipoproteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Blood Protein Disorders; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Electrophoresis; Glutamates; Humans; Hydrazines; Lipoproteins; Molecular Weight; Peptides; Serine; Valine | 1971 |
Application of gas-liquid radiochromatography to determination of the optical purity of carbon-14 labeled amino acids.
Topics: Alanine; Amino Acids; Carbon Isotopes; Chlorella; Chromatography, Gas; Cold Temperature; Drug Stability; Leucine; Methods; Proline; Serine; Stereoisomerism; Time Factors; Valine | 1971 |
[Dissociation of S- and P-variants of Bacillus brevis var. G.-B. on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Mutation; Nitrogen; Ornithine; Phenylalanine; Serine; Stimulation, Chemical; Threonine; Time Factors; Tryptophan; Valine | 1971 |
Germination of spores of Clostridium bifermentans by certain amino acids, lactate and pyruvate in the presence of sodium or potassium ions.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Clostridium; Glycine; Histidine; Lactates; Lysine; Ornithine; Phenylalanine; Potassium; Pyruvates; Serine; Sodium; Spores; Spores, Bacterial | 1971 |
The effect of diethyl pyrocarbonate on the transfer RNA of bovine muscle.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Aspartic Acid; Carbon Isotopes; Carbonates; Cattle; Chemical Phenomena; Chemistry; Chromatography; Chromatography, DEAE-Cellulose; Diaphragm; Histidine; Lens, Crystalline; Leucine; Liver; Lysine; Methionine; Muscles; Phenylalanine; Rats; RNA, Transfer; Serine; Tyrosine; Valine | 1971 |
[Antineoplastic effect and chemical structure of protamines of various origin].
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Depression, Chemical; Fishes; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Leukemia, Experimental; Lysine; Methionine; Mice; Proline; Protamines; Sarcoma 37; Serine; Threonine | 1971 |
Comparative study of various serine proteinases from microorganisms: specificity with oligopeptides.
Topics: Alanine; Aspergillus; Bacillus; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Disc; Endopeptidases; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Leucine; Peptides; Phenylalanine; Protease Inhibitors; Serine; Species Specificity; Streptomyces; Tyrosine | 1971 |
Permeability of lung capillaries and alveoli to non-electrolytes in the foetal lamb.
Topics: Alanine; Amino Acids; Animals; Capillary Permeability; Carbohydrate Metabolism; Erythritol; Female; Fetus; Injections, Intravenous; Inulin; Lipids; Lung; Lymph; Mannitol; Models, Biological; Permeability; Pregnancy; Pulmonary Alveoli; Serine; Sheep; Solubility; Sucrose; Thiourea; Urea; Water | 1971 |
Post mortem changes in the content and specific radioactivity of several amino acids in four areas of the rat brain.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Carbon Isotopes; Cerebellum; Cerebral Cortex; Glutamates; Glutamine; Glycine; Lactates; Male; Medulla Oblongata; Mesencephalon; Pons; Postmortem Changes; Rats; Serine | 1971 |
Allosteric properties of skeletal muscle pyruvate kinase.
Topics: Alanine; Allosteric Regulation; Animals; Cysteine; Drug Interactions; Enzyme Activation; Glyceric Acids; Hydrogen-Ion Concentration; Kinetics; Muscles; Phenylalanine; Pyruvate Kinase; Rabbits; Serine | 1971 |
Synthesis of some aminoacyl derivatives of 2-acetamido-2-deoxy- -D-glucopyranosylamine and of 2-amino-1-N-(4-L-aspartyl)-2-deoxy- -D-glucopyranosylamine.
Topics: Alanine; Amidohydrolases; Amino Acids; Animals; Aspartic Acid; Circular Dichroism; Fluorine; Glucosamine; Glutamates; Glycine; Glycopeptides; Hexosamines; Hydrogen-Ion Concentration; Hydrolysis; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Optical Rotation; Optical Rotatory Dispersion; Pyrans; Rats; Serine; Valine | 1971 |
Ultrafilterable ninhydrin-positive components of human parotid saliva.
Topics: Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Chromatography, Paper; Glutamates; Glycine; Humans; Indicators and Reagents; Leucine; Lysine; Male; Parotid Gland; Saliva; Serine; Taurine; Valine | 1967 |
Similarities and differences among specific tRNA's in mammalian tissues.
Topics: Alanine; Animals; Brain Chemistry; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cattle; Chick Embryo; Culture Techniques; Fibroblasts; Glycine; HeLa Cells; Humans; Kidney; Leucine; Liver; Lysine; Mice; Muscles; Neoplasms, Experimental; Phenylalanine; Rabbits; RNA, Transfer; Serine; Species Specificity; Threonine; Tritium | 1967 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Serine requirement in leukemic and normal blood cells.
Topics: Alanine; Asparagine; Aspartic Acid; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Culture Media; DNA, Neoplasm; Fibroblasts; Glucose; Glutamates; Glycine; Humans; In Vitro Techniques; Leukemia, Myeloid; Neoplasm Proteins; Proline; RNA, Neoplasm; Serine; Thymidine; Tritium; Uridine | 1969 |
Pyridoxine deficiency and brain amino acids.
Topics: Acetates; Alanine; Amino Acids; Aminobutyrates; Animals; Brain; Brain Chemistry; Diet; Glutamates; Glycine; Lactates; Methionine; Mice; Quaternary Ammonium Compounds; Seizures; Serine; Thiosemicarbazones; Tyrosine; Urea; Vitamin B 6 Deficiency | 1969 |
Isoaccepting transfer RNA's of L-M cells in culture and after tumor induction in C3H mice.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cell Line; Chromatography; Connective Tissue; Culture Media; Culture Techniques; Female; Fibrosarcoma; Glycine; Histidine; Isoleucine; Leucine; Ligases; Lysine; Male; Methionine; Mice; Phenylalanine; Proline; RNA, Transfer; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
[Distribution of free amino acids in plasma in patients with a chronic lymphatic and acute leukemia].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Citrulline; Cystine; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Leukemia, Lymphoid; Lysine; Methionine; Ornithine; Phenylalanine; Prednisolone; Proline; Serine; Threonine; Triethylenemelamine; Tyrosine; Valine; Vincristine | 1971 |
The role of beta-alanine in the biosynthesis of nitrate by Aspergillus flavus.
Topics: Alanine; Aspartic Acid; Aspergillus; Culture Media; In Vitro Techniques; Manometry; Nitrates; Peptones; Serine | 1965 |
Effects of ionizing radiation on free amino acids in Oedogonium cardiacum.
Topics: Alanine; Chromatography, Thin Layer; Eukaryota; Glutamates; Glycine; Histidine; Leucine; Methionine; Ornithine; Radiation Effects; Serine; Threonine; Valine | 1966 |
Separation of transfer ribonucleic acids by reverse phase chromatography.
Topics: Alanine; Arginine; Chromatography, Ion Exchange; Escherichia coli; In Vitro Techniques; Leucine; Phenylalanine; RNA, Bacterial; RNA, Transfer; Serine | 1965 |
Amino acid replacements associated with reversion and recombination within a coding unit.
Topics: Alanine; Amino Acids; Aspartic Acid; Cysteine; Escherichia coli; Genetic Code; Genetics; Glycine; In Vitro Techniques; Isoleucine; Ligases; Lysine; Mutation; Peptides; Serine; Tryptophan; Valine | 1965 |
Effect of amino acids and oxygen on chemotaxis in Escherichia coli.
Topics: Alanine; Amino Acids; Cell Biology; Chemotaxis; Escherichia coli; In Vitro Techniques; Oxygen; Serine | 1966 |
Enzymatic formation of beta-cyanoalanine from cyanide by Escherichia coli extracts.
Topics: Adenosine Triphosphate; Alanine; Carbon Isotopes; Chemical Phenomena; Chemistry; Cyanides; Cysteine; Escherichia coli; Magnesium; Serine; Sulfides; Threonine | 1965 |
Occurrence of hydroxypyruvate-L-glutamate transaminase in Escherichia coli and its separation from hydroxypyruvate-phosphate-L-glutamate transaminase.
Topics: Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry; Culture Media; Escherichia coli; Glutamates; Glycine; Mutation; Pyruvates; Serine; Spectrophotometry; Transaminases | 1966 |
Initiation of E. coli proteins.
Topics: Alanine; Bacterial Proteins; Chromatography, Paper; Dipeptides; Electrophoresis; Escherichia coli; Formates; Methionine; Models, Theoretical; Peptide Hydrolases; RNA, Messenger; Serine | 1966 |
Imidazolylacetolphosphate:L-glutamate aminotransferase. Composition and substructure.
Topics: Alanine; Ammonia; Arginine; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Electrophoresis; Genes; Glycine; Histidine; Leucine; Methionine; Molecular Biology; Molecular Weight; Peptides; Phenylalanine; Proline; Salmonella typhimurium; Serine; Threonine; Transaminases; Tyrosine; Valine | 1967 |
[Endogenous pellagra without hyperaminoaciduria].
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Arginine; Chromatography, Paper; Diagnosis, Differential; Electroencephalography; Glutamates; Glutamine; Hartnup Disease; Histidine; Humans; Lysine; Male; Pellagra; Serine; Skin Manifestations; Threonine | 1969 |
Effect of urea on the optical rotatory dispersion of diketopiperazines of L-serine, L-alanine, L-lysine, L-valine, and L-valylglycine.
Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry; Dipeptides; Glycine; Lysine; Methods; Optical Rotatory Dispersion; Peptides; Piperazines; Rotation; Serine; Spectrophotometry; Stereoisomerism; Ultraviolet Rays; Urea; Valine; Water | 1969 |
Studies on substrate induction of serine dehydratase of rat liver.
Topics: Adrenalectomy; Alanine; Amino Acids; Ammonia; Animals; Antibodies; Blood Glucose; Carbon Isotopes; Diabetes Mellitus, Experimental; Diet; Enzyme Activation; Hydro-Lyases; Insulin; L-Serine Dehydratase; Liver; Male; Nitrogen; Plasma; Proteins; Pyruvates; Rats; Serine; Time Factors; Triamcinolone; Urea | 1969 |
Changes in free amino acids of tomato fruit under pathogenesis.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Fruit; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Plant Diseases; Serine; Threonine; Tyrosine; Valine | 1969 |
Liver-L-alanine-glyoxylate and L-serine-pyruvate aminotransferase activities: an apparent association with gluconeogenesis.
Topics: Alanine; Animals; Anura; Dogs; Gluconeogenesis; Glycine; Glyoxylates; Liver; Pyruvates; Rabbits; Rats; Serine; Swine; Transaminases | 1969 |
Studies on amino acid racemases. I. Partial purification and properties of the alanine racemase from Lactobacillus fermenti.
Topics: Acetates; Alanine; Aminobutyrates; Aspartic Acid; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Computers; Cysteine; Drug Stability; Glutamates; Glutathione; Hydrogen-Ion Concentration; Isomerases; Kinetics; Lactobacillus; Mercaptoethanol; Methods; Models, Biological; Models, Chemical; Pyridoxal Phosphate; Serine; Stereoisomerism; Temperature | 1969 |
[Comparative study of the alanine-glyoxylate transaminase and malate synthetase in Neurospora crassa].
Topics: Acetates; Alanine; Citrates; Enzyme Induction; Glycine; Glyoxylates; Lyases; Malates; Mutation; Neurospora; Pyruvates; Serine; Transaminases | 1969 |
Transaminase activity in sheep rumen content.
Topics: Alanine; Alanine Transaminase; Animals; Arginine; Aspartic Acid; Cysteine; Eukaryota; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Leucine; Methionine; Phenylalanine; Rumen; Serine; Sheep; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
[Chemical and physico-chemical properties of placental protein with antineoplastic effect].
Topics: Alanine; Amino Acids; Ammonia; Antineoplastic Agents; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Electrophoresis; Female; Glutamates; Glycine; Histidine; Humans; Leucine; Lysine; Phenylalanine; Placenta; Proline; Proteins; Serine; Threonine; Tyrosine; Valine | 1969 |
Biosynthesis of ergot alkaloids. Origin of the side chain of ergometrine.
Topics: Alanine; Alcohols; Carbon Isotopes; Ergolines; Ergonovine; Oxidation-Reduction; Poaceae; Serine; Tritium | 1969 |
[The effect of nutrition on the amino acid sequence of the serine containing murein of Staphylococcus epidermis strain 24].
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Cell Wall; Chromatography, Paper; Culture Media; Glutamates; Glycine; Muramidase; Serine; Staphylococcus | 1969 |
[On the capability of the members of the genus Aeromonas to use amino acids as sole source of carbon].
Topics: Aeromonas; Alanine; Amino Acids; Arginine; Asparagine; Culture Media; Glutamates; Histidine; Leucine; Methionine; Phenylalanine; Serine; Species Specificity | 1969 |
Study on the amino acid composition in the cornea of hypophysectomized rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cornea; Cystine; Electrophoresis; Glutamates; Glycine; Growth Hormone; Histidine; Hypophysectomy; Leucine; Lysine; Methionine; Phenylalanine; Pituitary Gland; Rats; Serine; Threonine; Tyrosine | 1969 |
Amino acid content of muscle and plasma with altered pH.
Topics: Acidosis, Respiratory; Alanine; Alkalosis; Amino Acids; Animals; Aspartic Acid; Carbon Dioxide; Cell Membrane; Citrulline; Extracellular Space; Glutamine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Male; Muscles; Partial Pressure; Potassium Deficiency; Rats; Serine; Threonine; Valine | 1970 |
Accumulation of amino acids by Moniliformis dubius (Acanthocephala).
Topics: Alanine; Amino Acids; Carbon Isotopes; Culture Media; Glutamates; Helminths; Kinetics; Leucine; Molecular Weight; Serine; Sucrose | 1970 |
Peptides of a biologically active tryptic digest of bovine growth hormone.
Topics: Alanine; Amino Acids; Animals; Arginine; Biological Assay; Bone and Bones; Cattle; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis, Disc; Growth Hormone; Hypophysectomy; Molecular Weight; Peptides; Phenylalanine; Pituitary Gland; Rats; Serine; Trypsin; Ultracentrifugation; Valine | 1970 |
Large-scale preparation and some properties of penicillopepsin, the acid proteinase of Penicillium janthinellum.
Topics: Alanine; Carboxypeptidases; Chromatography; Crystallization; Electrophoresis; Filtration; Gels; Hot Temperature; Hydrogen-Ion Concentration; Penicillium; Peptide Hydrolases; Protein Denaturation; Serine; X-Ray Diffraction | 1970 |
The importance of dispensable amino acids for maximal growth in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Body Weight; Citrates; Diet; Glutamates; Glycine; Growth; Male; Nutritional Requirements; Proline; Rats; Serine | 1970 |
Biosynthesis of N-(alpha-hydroxyethyl) lysergamide, a metabolite of Claviceps paspali Stevens and Hall.
Topics: Acetates; Alanine; Alkaloids; Amides; Ascomycota; Carbon Isotopes; Formates; Indoles; Lactones; Mevalonic Acid; Pyruvates; Serine; Tryptophan | 1970 |
An amino-acid receptor in the guinea-pig ileum.
Topics: Alanine; Animals; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Glycine; Guinea Pigs; Ileum; Receptors, Drug; Serine | 1970 |
Studies on protein-like products from radiofrequency plasmas of Co, N2 and H2.
Topics: Alanine; Carbon Monoxide; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Glutamates; Glycine; Hydrogen; Nitrogen; Proteins; Pyridines; Serine; Tyrosine; Ultraviolet Rays | 1970 |
Levels of amino acids and proteins in Pacinian corpuscles of the cat.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cats; Chromatography, Paper; Denervation; Glutamates; Glutamine; Glycine; Mesentery; Nerve Endings; Nerve Tissue Proteins; Pargyline; Reserpine; Serine; Threonine | 1970 |
Effects of several factors on chemical condensation of mixed amino acid adenylates.
Topics: Adenine Nucleotides; Alanine; Amino Acids; Anhydrides; Chemical Phenomena; Chemistry; Dialysis; Electrophoresis; Magnesium; Methionine; Protein Biosynthesis; Serine; Time Factors | 1970 |
Derivation of partial sequence of human beta chain messenger RNA from mutation data.
Topics: Alanine; Arginine; Genetic Code; Glycine; Hemoglobins; Humans; Leucine; Mutation; Nucleotides; Proline; RNA, Messenger; Serine; Threonine; Valine | 1970 |
Action of (1,6-di-alanine)-oxytocin and (1,6-di-serine)-oxytocin on the rat uterus and mammary gland in vitro.
Topics: Alanine; Animals; Calcium; Female; In Vitro Techniques; Magnesium; Mammary Glands, Animal; Muscle Contraction; Oxytocin; Rats; Serine; Temperature; Uterus | 1970 |
Initiation of phi-X-174 RF-primed protein with N-formylmethionine.
Topics: Alanine; Carbon Isotopes; Cell-Free System; Coliphages; Detergents; DNA, Viral; Electrophoresis; Folic Acid; Formates; Gels; Genetic Code; Kinetics; Methionine; Peptide Hydrolases; RNA, Viral; Serine; Sulfuric Acids; Tritium; Viral Proteins | 1970 |
[Study of chemical composition and antineoplastic effect of protamines isolated from the milt of sturgeon fishes].
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Chromatography, Thin Layer; Depression, Chemical; Electrophoresis; Fishes; Glutamates; Glycine; Histidine; Leucine; Lysine; Male; Methionine; Mice; Molecular Weight; Neoplasms, Experimental; Nucleic Acids; Proline; Protamines; Sarcoma 37; Serine; Spectrum Analysis; Sulfates; Threonine; Ultraviolet Rays | 1970 |
Circadian ythm of human urinary amino acid excretion in fed and fasted states.
Topics: 17-Hydroxycorticosteroids; Adult; Alanine; Amino Acids; Asparagine; Circadian Rhythm; Cystinuria; Fasting; Feeding Behavior; Glutamates; Glutamine; Glycine; Humans; Male; Middle Aged; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1970 |
[Biosynthesis of gramicidin C on synthetic media with amino acids as the only N source].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Tyrothricin; Valine | 1970 |
Studies on nuclear amino acid transport and cation content in embryonic myocardium of the chick.
Topics: Alanine; Amino Acids; Animals; Arginine; Biological Transport, Active; Calcium; Carbon Isotopes; Cell Membrane Permeability; Cell Nucleus; Chick Embryo; Glutamates; Heart; Histocytochemistry; Magnesium; Myocardium; Potassium; Serine; Sodium; Stereoisomerism | 1970 |
Droplet countercurrent chromatography.
Topics: Alanine; Amino Acids; Chromatography; Countercurrent Distribution; Cystine; Dinitrophenols; Fluorocarbon Polymers; Ornithine; Proline; Serine; Threonine | 1970 |
Invertebrate structure proteins. Characterization of the operculum of the gastropod mollu Buccinum undatum.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbohydrates; Chromatography, Gas; Fucose; Galactose; Glucose; Glycine; Mannose; Mollusca; Proteins; Serine; Solubility; Solvents; X-Ray Diffraction; Xylose | 1970 |
Changes in the concentration of specific amino acids in the serum of experimentally malnourished pigs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Dietary Proteins; Female; Gluconeogenesis; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Protein Deficiency; Serine; Swine; Threonine; Tyrosine; Valine | 1970 |
Structure of macromolecular aggregates. II. Construction of model membranes from phospholipids and polypeptides.
Topics: Alanine; Animals; Brain; Cattle; Chemical Phenomena; Chemistry; Circular Dichroism; Glutamine; Lysine; Magnetic Resonance Spectroscopy; Membranes, Artificial; Microscopy, Electron; Optical Rotatory Dispersion; Ornithine; Osmolar Concentration; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Serine; Spectrum Analysis | 1970 |
Amino acid sequence analysis with methyl isothiocyanate. Resolution of the methylthiohydantoins by gas-liquid partition chromatography.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Bence Jones Protein; Cattle; Chromatography, Gas; Cysteine; Dipeptides; Glutamates; Hydantoins; Indicators and Reagents; Insulin; Methods; Serine; Serum Albumin, Bovine; Solvents; Thiocyanates; Threonine | 1970 |
Histidinemia.
Topics: Acetates; Acrylates; Adolescent; Alanine; Glycine; Histidine; Humans; Imidazoles; Lactates; Lyases; Male; Metabolism, Inborn Errors; Purpura, Thrombocytopenic; Pyruvates; Serine; Threonine | 1970 |
A comparison of properties of the alpha-lytic protease of Sorangium sp. and porcine elastase.
Topics: Alanine; Amino Acids; Animals; Deuterium; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Ketones; Kinetics; Leucine; Myxomycetes; Optical Rotatory Dispersion; Pancreatic Elastase; Peptide Hydrolases; Serine; Swine | 1970 |
Determination of pico-mole quantities of gamma-amino-butyric acid (GABA) and serotonin.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoradiography; Brain Chemistry; Carbon Isotopes; Cerebellum; Chromatography; Cysteine; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methods; Microchemistry; Phenylalanine; Proline; Radionuclide Imaging; Rats; Serine; Serotonin; Threonine; Tyrosine; Valine | 1970 |
Gas chromatographic determination of the configuration of alanine and serine in staphylococcal cell walls.
Topics: Alanine; Amino Acids; Cell Wall; Chromatography, Gas; Mutation; Serine; Staphylococcus | 1970 |
Amino acid permeability of pea chloroplasts as measured by osmotically determined reflection coefficients.
Topics: Alanine; Amides; Amino Acids; Cell Membrane Permeability; Chloroplasts; Glycine; Imines; Isoleucine; Leucine; Methionine; Osmolar Concentration; Osmotic Pressure; Phenylalanine; Plants; Proline; Serine; Sucrose; Threonine; Valine | 1970 |
Regulatory effects of ammonia on carbon metabolism in photosynthesizing Chlorella pyrenoidosa.
Topics: Alanine; Ammonia; Aspartic Acid; Autoradiography; Carbon Dioxide; Carbon Isotopes; Chlorophyta; Chromatography, Paper; Citrates; Citric Acid Cycle; Glutamates; Glutamine; Glycerophosphates; Hexosephosphates; Kinetics; Malates; Metabolism; Phosphoric Acids; Phosphorus Isotopes; Photosynthesis; Pyruvates; Serine; Sucrose; Uracil Nucleotides | 1970 |
Studies on the protein portion of thyroglobulin. Amino acid compositions and terminal amino acids of several thyroglobulins.
Topics: Alanine; Amides; Amino Acids; Animals; Aspartic Acid; Carboxypeptidases; Cattle; Cystine; Fluorine; Glutamates; Glycine; Humans; Hydrazines; Iodine; Leucine; Monosaccharides; Nitrobenzenes; Serine; Sheep; Swine; Thyroglobulin; Thyroid Gland | 1970 |
Indications of spatial relations among structures recognizing amino acids and Na+ at a transport receptor site.
Topics: Alanine; Amino Acids; Animals; Arginine; Binding Sites; Biological Transport; Canavanine; Columbidae; Erythrocytes; Guanidines; Lysine; Models, Biological; Models, Structural; Ornithine; Proline; Propionates; Rabbits; Reticulocytes; Serine; Sodium; Threonine | 1970 |
A lipoprotein characterizing obstructive jaundice. II. Isolation and partial characterization of the protein moieties of low density lipoproteins.
Topics: Alanine; Albumins; Amino Acids; Chemical Precipitation; Chemistry Techniques, Analytical; Cholestasis; Ethanol; Heparin; Humans; Immunochemistry; Immunoelectrophoresis; Lipoproteins; Peptides; Proteins; Serine; Threonine; Ultracentrifugation | 1970 |
[Hormonal regulation at the level of transfer RNA. I. Comparative study of transfer RNA from the liver of immature hens and laying hens].
Topics: Aging; Alanine; Animals; Carbon Isotopes; Chickens; Chromatography, Ion Exchange; Estradiol; Female; Isoleucine; Kinetics; Leucine; Ligases; Liver; Phenols; RNA, Transfer; Serine; Tritium; Valine | 1970 |
[Constitution of the hemoglobin of the toad Bufo bufo spinosus].
Topics: Alanine; Amino Acids; Animals; Anura; Arginine; Chromatography, Gel; Formates; Glycine; Hemoglobins; Histidine; Hydrazines; Lysine; Methionine; Peptide Hydrolases; Serine; Spectrum Analysis | 1970 |
[Effect of amino acids on the growth of Streptococcus lactis and biosynthesis of nisin].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Depression, Chemical; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Stimulation, Chemical; Streptococcus; Threonine; Tryptophan; Valine | 1970 |
Properties and substrate specificities of the phenylalanyl-transfer-ribonucleic acid synthetases of Aesculus species.
Topics: Alanine; Calcium Chloride; Caproates; Chromatography, DEAE-Cellulose; Glycine; Kinetics; Ligases; Magnesium; Phenylalanine; Plants; Potassium; RNA, Transfer; Seeds; Serine; Species Specificity | 1970 |
[Serological, chemical and immunochemical studies of erysipelas bacteria. VII. Presentation and general characteristics of the cell walls].
Topics: Alanine; Amino Sugars; Carbohydrates; Carbon Dioxide; Cell Wall; Erysipelothrix; Haptens; Immunoelectrophoresis; Lysine; Microscopy, Electron; Phosphorus; Serine | 1970 |
Nuclear magnetic resonance study of cyanoferrimyoglobin; identification of pseudocontact shifts.
Topics: Alanine; Ammonia; Animals; Cetacea; Chemical Phenomena; Chemistry; Cyanides; Deuterium; Dolphins; Electrons; Histidine; Horses; Magnetic Resonance Spectroscopy; Methylation; Myoglobin; Protons; Serine; Temperature | 1970 |
Amino acid sequence at the active center of succinate dehydrogenase.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Flavin-Adenine Dinucleotide; Flavins; Histidine; Myocardium; Peptides; Serine; Succinate Dehydrogenase; Thiocyanates; Threonine; Valine | 1970 |
Effect of vitamin B6 depletion in adult man on the plasma concentration and the urinary excretion of free amino acids.
Topics: Adult; Alanine; Amino Acids; Fasting; Glycine; Humans; Isoleucine; Leucine; Male; Pyridoxine; Serine; Threonine; Valine; Vitamin B 6 Deficiency | 1971 |
Nature of the cosubstrate action of Na+ and neutral amino acids in a transport system.
Topics: Alanine; Amino Acids; Animals; Arginine; Binding Sites; Biological Transport; Caproates; Carbon Isotopes; Columbidae; Erythrocytes; Kinetics; Lithium; Methionine; Rabbits; Reticulocytes; Serine; Sodium; Sodium Isotopes; Sulfhydryl Compounds | 1971 |
Variation in primary structure at a phosphorylation site in lysine-rich hostones.
Topics: Alanine; Amino Acid Sequence; Animals; Cattle; Chromatography, Ion Exchange; Histones; Liver; Lysine; Peptides; Phosphorus Isotopes; Phosphotransferases; Rabbits; Rats; Serine; Thymus Gland; Trypsin | 1971 |
[The flagellar apparatus of Rhodopseudomonas palustris. VI. Characterization of flagellin].
Topics: Alanine; Aspartic Acid; Bacterial Proteins; Electrophoresis; Flagella; Gels; Glycine; Leucine; Molecular Weight; Pseudomonas; Serine; Threonine; Ultracentrifugation | 1971 |
Nutrient media for plant-parasitic nematodes. II. Amino acid requirements of Aphelenchoides sp.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Fungi; Germ-Free Life; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Nematoda; Nutritional Requirements; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Biosynthesis of -cyanoalanine in Vicia sativa.
Topics: Alanine; Carbon Isotopes; Cyanides; Cysteine; Glutamates; Nitriles; Plants; Potassium; Protein Binding; Serine; Time Factors; Toxins, Biological | 1971 |
Amino acid metabolism in the isolated perfused rat liver.
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Chromatography; Glutamates; Glycine; In Vitro Techniques; Liver; Lysine; Male; Methionine; Nitrogen Isotopes; Perfusion; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Urea | 1971 |
The entry of amino acids into the skeletal muscle of the rat in vivo.
Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Biological Transport; Glycine; Leucine; Muscle Proteins; Muscles; Rats; Serine; Taurine; Tryptophan | 1971 |
[Use of methyl group labelled methionine as a source of Cl4 and H3 for the preliminary production of labelled olivomycin by biosynthesis].
Topics: Acetates; Actinomyces; Alanine; Amino Acids; Antibiotics, Antineoplastic; Aspartic Acid; Carbon Isotopes; Chloramphenicol; Depression, Chemical; Fermentation; Formates; Glucose; Glutamates; Glycine; Methionine; Olivomycins; Phenylalanine; Serine; Stimulation, Chemical; Time Factors; Tritium | 1971 |
[Dissociation of R- and P plus-variants of Bacillus brevis var. G.-B. during growth on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Valine | 1971 |
Gluconeogenesis in the isolated rat liver. Studies with bicarbonate-14C.
Topics: Acid-Base Equilibrium; Alanine; Animals; Aspartic Acid; Bicarbonates; Carbon Isotopes; Cattle; Chromatography, Paper; Electrophoresis; Gluconeogenesis; Glycerophosphates; Hydrogen-Ion Concentration; Kinetics; Lactates; Liver; Malates; Male; Oxygen; Partial Pressure; Perfusion; Pyridines; Pyruvates; Rats; Serine | 1971 |
Amino acid levels in plasma, liver, muscle, and kidney during and after exercise in fasted and fed rats.
Topics: Acidosis; Alanine; Amino Acids; Animals; Aspartic Acid; Fasting; Gluconeogenesis; Glutamates; Glutaminase; Glutamine; Glycine; Kidney; Liver; Lysine; Male; Muscles; Physical Exertion; Rats; Serine; Swimming | 1971 |
Serine transhydroxymethylase. Affinity of the active site for substrates, substrate analogues, and anions.
Topics: Alanine; Aldehydes; Aminoisobutyric Acids; Animals; Benzoates; Binding Sites; Chlorides; Cysteamine; Cysteine; Electrophoresis; Folic Acid; Glycine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Models, Biological; Organophosphonates; Phosphates; Potassium; Propionates; Pyridoxal Phosphate; Rabbits; Serine; Spectrophotometry; Stereoisomerism; Sulfates; Sulfhydryl Compounds; Sulfonic Acids; Thermodynamics; Threonine; Transferases; Ultracentrifugation | 1971 |
An aminopeptidase activity associated with brain ribosomes.
Topics: Alanine; Amides; Aminopeptidases; Animals; Aspartic Acid; Brain; Cattle; Glutamates; Kinetics; Methionine; Naphthalenes; Ribosomes; Serine; Valine | 1971 |
The influence of various -alkyl and -hydroxyalkyl substituents on the stability of dipeptides in dilute alkali.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Borates; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Dipeptides; Drug Stability; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Isomerism; Kinetics; Leucine; Potassium; Serine; Stereoisomerism; Threonine; Valine | 1971 |
Essential amino acids in the culture of Leishmania tarentolae.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Glucose; Glutamates; Glycine; Histidine; Leishmania; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Comparative studies on the primary structure of soluble and mitochondrial glutamic oxaloacetic transaminase isozymes. I. Similar peptides isolated by cyanogen bromide cleavage.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartate Aminotransferases; Aspartic Acid; Cell Fractionation; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Paper; Cyanides; Electrophoresis; Fluorescence; Hydroxybutyrates; Indenes; Isoenzymes; Isoleucine; Ketones; Leucine; Mitochondria, Muscle; Myocardium; Peptides; Serine; Solubility; Swine; Trypsin; Water | 1971 |
Comparative studies on the primary structure of soluble and mitochondrial glutamic oxaloacetic transaminase isozymes. II. Amino acid sequence of the amino terminal fragments.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aminobutyrates; Animals; Aspartate Aminotransferases; Chemical Phenomena; Chemistry; Chromatography, Paper; Chymotrypsin; Cyanides; Endopeptidases; Glutamates; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Hydroxybutyrates; Isoenzymes; Mitochondria, Muscle; Myocardium; Peptides; Phenylalanine; Proline; Serine; Solubility; Swine; Thiocyanates; Tryptophan; Valine | 1971 |
Transsulfuration in higher plants. Partial purification and properties of beta-cystathionase of spinach.
Topics: Alanine; Amino Acids; Benzoates; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Cysteine; Drug Stability; Edible Grain; Ethylmaleimide; Homocysteine; Hydro-Lyases; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; Models, Structural; Plants; Pyridoxal Phosphate; Pyruvates; Quaternary Ammonium Compounds; Serine; Species Specificity; Spectrophotometry; Stereoisomerism; Sulfates; Sulfides; Sulfur; Triticum | 1971 |
Metabolism of amino acids in plants. I. Changes in the soluble amino acid fractions of bushbean seedlings (Phaseolus vulgaris L.) and the development of transaminase activity.
Topics: Alanine; Alanine Transaminase; Amino Acids; Asparagine; Aspartate Aminotransferases; Cadmium; Chromatography, Paper; Colorimetry; Darkness; Indenes; Ketones; Light; Nitrogen; Plant Development; Plant Physiological Phenomena; Plant Proteins; Plants; Radiation Effects; Seeds; Serine; Solubility; Threonine; Time Factors; Transaminases; Trichloroacetic Acid; Valine | 1971 |
Molecular transport. I. In vivo studies of transport mutants of Neurospora crassa with altered amino acid competition patterns.
Topics: Alanine; Arginine; Aspartic Acid; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Crosses, Genetic; Genetics, Microbial; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Serine; Stereoisomerism; Threonine; Tyrosine; Valine | 1971 |
Studies on adrenal steroid hydroxylases. The reactivity of triphenyl phosphine with labile sulfur in adrenal iron-sulfur protein (adrenodoxin).
Topics: Adrenal Glands; Air; Alanine; Animals; Benzene Derivatives; Bromine; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Cysteine; Ferredoxins; Hydrocarbons, Halogenated; Iron; Kinetics; Models, Structural; Nickel; Nitrogen; Organometallic Compounds; Phosphines; Pyruvates; Serine; Spectrophotometry; Sulfhydryl Compounds; Sulfides; Trichloroacetic Acid; Tritium | 1971 |
Incorporation of pyrimidine deoxyribonucleosides into liver lipids and other components.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Aspartic Acid; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Deoxyribonucleosides; Deoxyuridine; DNA; Fatty Acids; Glutamates; Glycerides; Glycerol; Glycerylphosphorylcholine; Hydrolysis; Lipids; Liver; Male; Methionine; Mice; Microsomes, Liver; Mitochondria, Liver; Nucleosides; Phosphatidylcholines; Phosphatidylethanolamines; Protein Biosynthesis; Rats; Serine; Thymidine; Thymine; Tritium | 1971 |
The free amino acid concentrations in maternal and foetal plasmas in the pregnant ewe.
Topics: Alanine; Amino Acids; Animals; Chromatography, Ion Exchange; Female; Fetus; Glycine; Maternal-Fetal Exchange; Pregnancy; Pregnancy, Animal; Serine; Sheep; Threonine; Umbilical Arteries; Umbilical Veins | 1971 |
[Free amino acids and other ninhydrin-positive substances in the normal horny layer and in psoriasis scales].
Topics: Alanine; Amino Acids; Ammonia; Asparagine; Chromatography; Citrulline; Cysteine; Glycine; Histidine; Humans; Imidazoles; Phenylalanine; Proline; Psoriasis; Serine; Skin; Taurine; Threonine; Urea | 1967 |
[Chemistry of the antibiotic A-128 (neotelomycin)--qualitative and quantitative amino acid composition].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Aspartic Acid; Chemistry Techniques, Analytical; Chromatography, Paper; Electrophoresis; Glycine; Proline; Serine; Threonine; Tryptophan | 1967 |
[Hyperaminoaciduria in children suffering from progressive muscular dystrophy].
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Arginine; Aspartic Acid; Child; Child, Preschool; Creatine; Creatinine; Female; Glutamates; Histidine; Humans; Leucine; Lysine; Male; Methionine; Muscular Dystrophies; Nitrogen; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
[Quantitative paper chromatography amino acid determination. Stanardization of the procedure and method of testing of new paper types].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography, Paper; Cysteine; Glutamates; Glycine; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Methods; Paper; Phenylalanine; Serine; Spectrum Analysis; Sulfones; Threonine; Tyrosine; Ultraviolet Rays; Valine | 1967 |
[Studies on the physicochemical properties of basic protein of the brain].
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Chemical Phenomena; Chemistry; Chromatography, Gel; Electrophoresis, Disc; Glutamates; Glycine; Hydrogen-Ion Concentration; Leucine; Molecular Weight; Nerve Tissue Proteins; Serine; Ultracentrifugation; Valine | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Two trypsin inhibitors from porcine pancreatic juice.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Enzyme Precursors; Glutamates; Glutamine; Guanidines; In Vitro Techniques; Kallikreins; Molecular Weight; Pancreatic Juice; Proline; Serine; Species Specificity; Spectrum Analysis; Swine; Threonine; Trypsin; Trypsin Inhibitors; Ultracentrifugation; Ultraviolet Rays | 1968 |
Dipeptidyl arylamidase II of the pituitary. Properties of lysylalanyl-beta-naphthylamide hydrolysis: inhibition by cations, distribution in tissues, and subcellular localization.
Topics: Acid Phosphatase; Alanine; Animals; Arginine; Cattle; Centrifugation, Density Gradient; Chromatography, Paper; Cytoplasm; Dipeptides; Endopeptidases; Glycine; Hydrogen-Ion Concentration; Kidney; Kinetics; Leucine; Lithium; Lysine; Lysosomes; Methionine; Naphthalenes; Nucleosides; Pituitary Gland; Potassium; Proline; Protease Inhibitors; Puromycin; Rats; Serine; Sodium; Spleen; Thyroid Gland; Tromethamine; Tyrosine | 1968 |
Purification and properties of an anionic zymogen of phospholipase A from porcine pancreas.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Autolysis; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis; Electrophoresis, Disc; Enzyme Precursors; Glutamates; Glycine; Isoflurophate; Isoleucine; Molecular Weight; Pancreas; Peptide Hydrolases; Peptides; Phospholipases; Serine; Swine; Trypsin | 1968 |
Studies on hyaluronic acid. II. The protein component(s) of rooster comb hyaluronic acid.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Autoanalysis; Chemical Phenomena; Chemistry; Chickens; Chromatography, Ion Exchange; Comb and Wattles; Glutamates; Glycine; Hyaluronic Acid; Male; Serine; Uronic Acids; Viscosity | 1968 |
The erythrocyte plasma distribution of amino acids in health and disease.
Topics: Acute Disease; Adolescent; Adult; Alanine; Amino Acids; Anemia, Hemolytic; Anemia, Pernicious; Bronchitis; Bronchopneumonia; Chromatography, Paper; Erythrocytes; Female; Glutamates; Glutamine; Glycine; Hepatitis; Humans; Hyperthyroidism; Infections; Inflammation; Isoleucine; Leucine; Male; Methionine; Neoplasms; Plasma; Pyelitis; Serine; Threonine; Valine | 1968 |
[On a new carboxypeptidase (EC 3.4.2.?) from spleen].
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Carboxypeptidases; Cattle; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Glutamates; Glycine; Kinetics; Leucine; Peptides; Serine; Spleen; Tyrosine; Valine | 1968 |
Isolation and identification of alpha-amino aldehydes in collagen.
Topics: Air Sacs; Alanine; Aldehydes; Amino Alcohols; Animals; Aspartic Acid; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Thin Layer; Collagen; Cyprinidae; Gelatin; Glycine; Hydrazones; Lactones; Lysine; Oxidation-Reduction; Rats; Serine; Skin; Spectrum Analysis; Threonine; Tritium | 1968 |
The distribution of amino acids between erythrocytes and plasma in fetal and maternal blood.
Topics: Alanine; Amino Acids; Biological Transport, Active; Chromatography, Paper; Erythrocytes; Female; Glutamates; Glutamine; Glycine; Humans; Infant, Newborn; Isoleucine; Leucine; Maternal-Fetal Exchange; Methionine; Placenta; Plasma; Pregnancy; Serine; Threonine; Valine | 1968 |
Incorporation of 2-14C tryptophan into the free amino acid spectrum of Vinca minor L.
Topics: Alanine; Amino Acids; Autoradiography; Carbon Isotopes; Chromatography, Paper; Leucine; Phenylalanine; Plants, Medicinal; Serine; Tryptophan; Valine | 1968 |
A study of 2,4,6-trinitrobenzenesulfonic acid for automated amino acid chromatography.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Autoanalysis; Chromatography; Cystine; Glycine; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Isoleucine; Leucine; Lysine; Methionine; Methods; Nitrobenzenes; Phenylalanine; Proline; Serine; Spectrophotometry; Sulfonic Acids; Temperature; Threonine; Tryptophan; Tyrosine; Urea; Valine | 1968 |
Primary structure of insoluble tendon collagen. 3. Analysis of products of tryptic digestion of native collagen.
Topics: Achilles Tendon; Alanine; Aldehydes; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cysteine; Electrophoresis; Glutamine; Glycine; Hexosamines; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Proline; Serine; Sulfur; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Trace metal requirements for malformin biosynthesis.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Aspergillus; Chromium; Cobalt; Copper; Cysteine; Glutamine; Glycine; Histidine; Iron; Isoleucine; Leucine; Lysine; Manganese; Metals; Molybdenum; Peptide Biosynthesis; Phenylalanine; Plant Growth Regulators; Proline; Serine; Trace Elements; Tryptophan; Tyrosine; Valine; Zinc | 1968 |
[Separation of low molecular weight ninhydrine positive substances in pleural punctates. Contribution to the problem of inflammation].
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chromatography; Chromatography, Gel; Electrophoresis; Glutamates; Glycine; Inflammation; Lysine; Paper; Peptides; Pleural Effusion; Rabbits; Serine; Trypan Blue; Valine | 1968 |
C-terminal analysis of histidinol dehydrogenase from Neurospora crassa.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acids; Ascomycota; Carboxypeptidases; Glutamates; Hydrazines; Isoleucine; Leucine; Serine; Spectrophotometry; Valine | 1968 |
Species specificity of the conformation of silk fibroin in solution.
Topics: Alanine; Alcohols; Amino Acid Sequence; Amino Acids; Animals; Bombyx; Chemical Phenomena; Chemistry; Dioxins; Fibroins; Glycine; Infrared Rays; Insecta; Optical Rotatory Dispersion; Serine; Solubility; Species Specificity; Spectrum Analysis | 1968 |
Terminal amino acids of aspartate aminotransferase isozymes.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartate Aminotransferases; Carboxypeptidases; Chromatography, Paper; Glutamine; Hydrazines; Isoenzymes; Lysine; Myocardium; Serine; Swine; Tritium | 1968 |
Enzymic studies on the biosynthesis of amino acids from lactate by peptostreptococcus elsdenii.
Topics: Alanine; Alanine Transaminase; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Cell-Free System; Chromatography, Paper; Citric Acid Cycle; Electrophoresis; Glutamates; Lactates; Malate Dehydrogenase; Peptostreptococcus; Rumen; Serine; Spectrophotometry | 1968 |
Differences in the amino acid compositions of allogeneic guinea pig transplantation antigens.
Topics: Alanine; Amino Acids; Animals; Antigens; Chromatography, Gel; Electrophoresis; Guinea Pigs; Isoleucine; Leucine; Lymphoid Tissue; Serine; Sound; Transplantation Immunology; Transplantation, Homologous; Ultrasonics; Valine | 1968 |
Calf and pea histone IV. I. Amino acid compositions and the identical COOH-terminal 19-residue sequence.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Evolution; Bromine; Cattle; Chromatography, Gel; Chymotrypsin; Cyanides; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Plants; Proline; Serine; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Incorporation of serine-U-14C into beta-cyanoalanine and gamma-glutamyl-beta-cyanoalanine in Vicia sativa.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; Glutamates; Nitriles; Peptide Biosynthesis; Plant Development; Plants; Seeds; Serine | 1968 |
Two procedures for accelerated separation of amino acids by column chromatography.
Topics: Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Buffers; Chromatography, Ion Exchange; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Methods; Phenylalanine; Proline; Serine; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Gas chromatographic behavior of trimethylsilylated phenylthiohydantoin amino acids.
Topics: Alanine; Amino Acids; Arginine; Chromatography, Gas; Glutamates; Glutamine; Hydantoins; Leucine; Methionine; Methods; Methylation; Phenylalanine; Proline; Serine; Silicon; Spectrum Analysis; Tyrosine | 1968 |
Carbohydrate formation from various precursors in noenatal rat liver.
Topics: Alanine; Animals; Animals, Newborn; Carbon Isotopes; Caseins; Gluconeogenesis; Glucose; Glycerol; Glycogen; Hydro-Lyases; In Vitro Techniques; Lactates; Liver; Oxaloacetates; Rats; Serine; Threonine | 1968 |
Naturally occurring low-molecular-weight peptides from the blowfly Phormia regina.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Dipeptides; Diptera; Glutamine; Glycine; Isoleucine; Lysine; Peptides; Serine; Valine | 1968 |
[On the influence of the starting position on migration of substances in paper electrophoresis].
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Asparagine; Cysteine; Electrophoresis; Glucose; Glutamates; Glutamine; Glycine; Histidine; Leucine; Lysine; Methionine; Serine; Serum Albumin; Taurine; Tryptophan | 1968 |
States of amino acid residues in proteins. XVI. Naphthoquinones with two sulfonic groups as a reagent for discrimation of amino groups in proteins.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chymotrypsin; Colorimetry; Freezing; Glycine; Histidine; Hydrogen-Ion Concentration; Imidazoles; Indicators and Reagents; Insulin; Lysine; Muramidase; Naphthoquinones; Proline; Proteins; Ribonucleases; Serine; Spectrophotometry; Sulfonic Acids; Tryptophan; Tyrosine | 1968 |
Role of streptomycin in the life of Streptomyces griseus: streptidine-containing fractions in the cell walls of Streptomyces griseus strains.
Topics: Alanine; Arginine; Cell Wall; Chromatography, Ion Exchange; Chromatography, Paper; Guanidines; Hydrogen-Ion Concentration; Infrared Rays; Methods; Serine; Spectrum Analysis; Streptomyces; Streptomycin; Threonine | 1968 |
Transferrin DChi: the amino acid substitution.
Topics: Alanine; Amino Acid Sequence; Arginine; Aspartic Acid; Glutamates; Histidine; Humans; Lysine; Peptides; Proline; Serine; Transferrin; Trypsin; Valine | 1968 |
Amino acid binding to luteinizing hormone.
Topics: Acetates; Alanine; Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Cellulose; Chromatography, Gel; Countercurrent Distribution; Electrophoresis; Glycine; Glycoproteins; Guanidines; Luteinizing Hormone; Peptides; Protein Binding; Serine; Sheep; Threonine | 1968 |
[An after-effect in x-ray irradiated aqueous solutions of lysine and other aliphatic amino acids].
Topics: 1-Propanol; Alanine; Amino Acids; Aminobutyrates; Butylamines; Butyrates; Glycine; Heterocyclic Compounds; Lysine; Propionates; Radiation Effects; Radiochemistry; Serine; Solutions; Spectrophotometry | 1968 |
[The free amino acids in a water-soluble superficial film of the skin in exanthematous diseases in childhood].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chickenpox; Child; Chromatography, Paper; Female; Glutamine; Glycine; Histidine; Humans; Leucine; Male; Measles; Rubella; Scarlet Fever; Serine; Sweat; Valine | 1968 |
Autodigestion of the main proteolytically active component of the stem bromelain.
Topics: Alanine; Arginine; Bromelains; Chromatography; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Peptides; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1968 |
Amino acids involved in chromophore-protein linkages in phycoerythrins.
Topics: Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Pigments, Biological; Proteins; Serine; Threonine | 1968 |
[Levels of free amino acids in the blood and heart muscle in the human at various periods of myocardial infarct (clinical anatomical parallels)].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Erythrocytes; Glutamates; Glycine; Histidine; Histocytochemistry; Humans; Isoleucine; Leucine; Lysine; Methods; Middle Aged; Myocardial Infarction; Myocardium; Necrosis; Phenylalanine; Serine; Threonine; Time Factors; Tyrosine; Valine | 1968 |
Number of polypeptide components in bacteriophage T2L contractile sheaths.
Topics: Alanine; Amino Acids; Aspartic Acid; Carboxypeptidases; Coliphages; Glutamine; Glycine; Hydrazines; Leucine; Peptides; Serine; Threonine; Tryptophan; Valine | 1968 |
[Crystalline leucine aminopeptidase from bovine lens. Amino acid composition and N-terminal amino acids, II].
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Cattle; Crystallography; Formates; Glutamates; Glutamine; Glycine; Lens, Crystalline; Leucine; Leucyl Aminopeptidase; Lysine; Serine; Threonine | 1968 |
Piperonylic acid conjugates with alanine, glutamate, glutamine, glycine, and serine in living houseflies.
Topics: Alanine; Amino Acids; Animals; Benzoates; Dioxoles; Female; Glutamates; Glutamine; Glycine; Houseflies; Serine | 1968 |
Quinoxaline studies. XIV. Potential anticancer agents. Some quinoxaline amino acid and dipeptide derivatives related to quinoxaline antibiotics.
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Dipeptides; Glycine; Leukemia L1210; Methionine; Mice; Quinoxalines; Serine; Valine | 1969 |
Beta-cyanoalanine formation by Chromobacterium violaceum.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; Carbon Isotopes; Chromobacterium; Cyanides; Formaldehyde; Glycine; Methionine; Serine; Succinates | 1969 |
Determination of dinitrophenylamino acids in structural proteins by chromatography on nylon powder columns. II. The ether-soluble dinitrophenylamino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography; Dinitrophenols; Glutamates; Glycine; Hydrogen-Ion Concentration; Methods; Nylons; Proteins; Serine; Threonine; Valine | 1969 |
Cyanide metabolism in higher plants. IV. Purification and properties of the beta-cyanolanine synthase of blue lupine.
Topics: Alanine; Cell-Free System; Centrifugation, Density Gradient; Chromatography, Gel; Colorimetry; Cyanides; Cysteine; Electrophoresis; Lyases; Plants, Edible; Serine; Sulfides; Toxins, Biological | 1969 |
[Modification of lipid metabolism with solvosterol].
Topics: Aged; Alanine; Arteriosclerosis; Cholesterol; Colorimetry; Glycine; Humans; Injections, Intramuscular; Isoleucine; Lipids; Lipoproteins; Male; Serine; Valine | 1969 |
Mechanism of autolysis of isolated cell walls of Staphylococcus aureus.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Bacteriolysis; Cell Wall; Chromatography, Gel; Chromatography, Ion Exchange; Glucosamine; Glutamates; Glycine; Hexosamines; Serine; Staphylococcus | 1969 |
Formation and spectral properties of copper (II) ion complexes of the NH2-terminal pentapeptide from sperm whale myoglobin and of certain tetra- and pentapeptides.
Topics: Alanine; Amino Acids; Animals; Cetacea; Chemical Phenomena; Chemistry; Chromatography, Paper; Copper; Glutamates; Glycine; Histidine; Leucine; Light; Myoglobin; Peptides; Potentiometry; Rotation; Serine; Spectrophotometry; Spectrum Analysis; Stereoisomerism; Valine | 1969 |
Isolation and characterization of alkaline proteinase of Aspergillus flavus.
Topics: Alanine; Amino Acids; Aspergillus; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Disc; Glycine; Isoflurophate; Molecular Weight; Peptide Hydrolases; Phosphorus Isotopes; Serine; Ultracentrifugation | 1969 |
Inhibition of hepatic gluconeogenesis by ethanol.
Topics: Alanine; Alcohol Oxidoreductases; Animals; Ethanol; Gluconeogenesis; In Vitro Techniques; Lactates; Liver; Oleic Acids; Perfusion; Pyrazoles; Pyruvates; Rats; Serine | 1969 |
Effect of glucagon on concentration of several free amino acids in plasma.
Topics: Alanine; Amino Acids; Arginine; Citrulline; Cystine; Depression, Chemical; Fasting; Female; Glucagon; Glycine; Histidine; Humans; Leucine; Liver; Lysine; Male; Methionine; Nitrogen; Phenylalanine; Progesterone; Proline; Serine; Threonine; Tyrosine; Valine | 1969 |
The peptidoglycan in walls of Butyribacterium rettgeri.
Topics: Alanine; Amidohydrolases; Amino Acid Sequence; Amino Acids; Cell Wall; Chromatography, Gel; Chromatography, Thin Layer; Eubacterium; Glutamates; Hexosamines; Lysine; Muramidase; Ornithine; Peptide Biosynthesis; Peptide Hydrolases; Polysaccharides, Bacterial; Proteins; Serine; Streptomyces | 1969 |
A study of transfer ribonucleic acid in Neurospora. I. The attachment of amino acids and amino acid analogs.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Carbon Isotopes; Chromatography, Ion Exchange; Ethionine; Glutamates; Glutamine; Glycine; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methionine; Neurospora; Phenylalanine; Phosphates; RNA, Transfer; Serine; Sulfhydryl Compounds; Time Factors; Tritium | 1969 |
Isolation and characterization of the peptides derived from the alpha-1 chain of chick bone collagen after cyanogen bromide cleavage.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Bone and Bones; Bromine; Chickens; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cyanides; Lysine; Methionine; Molecular Weight; Peptides; Rats; Serine; Skin; Spectrophotometry; Trypsin | 1969 |
Evidence that the activity of elastase is not dependent on the ionization of its N-terminal amino group.
Topics: Alanine; Animals; Electrophoresis; Hydrogen-Ion Concentration; Pancreatic Elastase; Serine; Spectrophotometry; Swine; Valine | 1969 |
Regulation of 6-methylsalicylate and patulin synthesis in Penicillium urticae.
Topics: Alanine; Cycloheximide; Penicillium; Phenylalanine; Pyrans; Salicylates; Serine; Valine | 1969 |
Circadian periodicity of blood amino acids in normal and adrenalectomized mice.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Circadian Rhythm; Cystine; Densitometry; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Mice; Serine; Threonine; Tryptophan; Tryptophan Oxygenase; Tyrosine; Valine | 1969 |
Chemical characterization of a non-covalently linked peptide from plakalbumin.
Topics: Alanine; Albumins; Amino Acid Sequence; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry; Hydrazines; Methods; Ovalbumin; Peptides; Proline; Serine; Urea | 1969 |
Taxonomic comparison of the amino termini of microbial cell proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Bacteria; Bacterial Proteins; Biological Evolution; Eukaryota; Fungi; Methionine; Proteins; Serine; Threonine | 1969 |
Structures of the cell wall peptidoglycans of Staphylococcus epidermidis Texas 26 and Staphylococcus aureus Copenhagen. I. Chain length and average sequence of cross-bridge peptides.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Cell Wall; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Glycerophosphates; Glycine; Hexosamines; Lysine; Pentosephosphates; Peptides; Polysaccharides, Bacterial; Serine; Species Specificity; Staphylococcus | 1969 |
Encephalopathy in combination with a new pattern of aminoaciduria.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Brain; Brain Diseases; Central Nervous System; Chromatography; Cyanosis; Dyspnea, Paroxysmal; Electroencephalography; Exchange Transfusion, Whole Blood; Humans; Hyperbilirubinemia; Infant; Infant, Newborn; Infant, Premature, Diseases; Male; Serine; Spectrophotometry; Threonine | 1969 |
Amino acid feeding studies: effects of various nonessential nitrogen sources and of added water.
Topics: Alanine; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Body Weight; Diet; Glutamates; Glycine; Male; Nitrogen; Proline; Rats; Serine | 1969 |
Urinary amino acid and peptide excretion patterns in patients with muscular dystrophy (Duchenne). A preliminary study with the autoanalyzer.
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Autoanalysis; Child; Child, Preschool; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Muscular Dystrophies; Peptides; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1969 |
Amino acid transport in adult diaphyseal bone: contrast with amino acid transport mechanisms in fetal membranous bone.
Topics: Age Factors; Alanine; Amides; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Bone and Bones; Carbon Isotopes; Cyanides; Depression, Chemical; Female; Fluorides; Hydroxyproline; Imines; Membranes; Methods; Pregnancy; Proline; Rats; Serine; Sodium; Sucrose; Tibia; Time Factors; Tritium | 1969 |
Fractionation on benzoylated DEAE-cellulose of tRNA from tobacco mosaic virus-infected tobacco leaves.
Topics: Alanine; Aspartic Acid; Chromatography; Histidine; Isoleucine; Leucine; Methionine; Nicotiana; Phenylalanine; Plants, Toxic; RNA, Transfer; RNA, Viral; Serine; Tobacco Mosaic Virus | 1969 |
Amino acid composition of beta-caseins from the milks of Bos indicus and Bos taurus cows: a comparative study.
Topics: Acrylates; Alanine; Amino Acids; Animals; Arginine; Autoanalysis; Caseins; Cattle; Cellulose; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Electrophoresis; Gels; Glutamates; Histidine; Lysine; Milk; Peptides; Phosphorus; Serine; Species Specificity; Threonine; Trypsin; Tryptophan | 1969 |
Typical hyperaminoaciduria after high doses of 6-azauridine triacetate.
Topics: Acetates; Adult; Alanine; Amino Acids; Chromatography, Paper; Glycine; Humans; Middle Aged; Psoriasis; Serine; Triazines; Urine | 1969 |
[Studies on the metabolism of glycerol in the central nervous system. I. Incorporation of glycerol carbon into the free amino acids of mouse brain].
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Carbon Isotopes; Glucose; Glutamates; Glutamine; Glycerol; Glycine; Male; Mice; Serine | 1969 |
[On the primary structure of the specific trypsin inhibitor from sheep pancreas].
Topics: Alanine; Alkylation; Amino Acid Sequence; Animals; Chromatography, Ion Exchange; Pancreas; Peptides; Serine; Sheep; Trypsin Inhibitors | 1969 |
Glycine-producing transaminase activity in extracts of spinal cord.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Carbon Isotopes; Cats; Chromatography, Paper; Cystine; Glutamates; Glutamine; Glycine; Glyoxylates; Rats; Serine; Spinal Cord; Tissue Extracts; Transaminases | 1969 |
Structure of Mn2+ and Cu2+ complexes with L-methionine, S-methyl-L-cysteine, L-threonine and L-serine.
Topics: Alanine; Amino Acids; Aminobutyrates; Binding Sites; Chemical Phenomena; Chemistry; Copper; Cysteine; Drug Stability; Keto Acids; Magnetic Resonance Spectroscopy; Manganese; Methionine; Serine; Sulfur; Threonine | 1969 |
Reversal of the growth inhibitory action of glycine and glycylglycine by alanylalanine in Mycobacterium smegmatis.
Topics: Alanine; Amino Sugars; Chromatography, Paper; Depression, Chemical; Dipeptides; Glycine; Mycobacterium; Serine; Spectrophotometry; Stereoisomerism; Stimulation, Chemical; Ultraviolet Rays | 1969 |
Histones in early embryogenesis.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Echinodermata; Electrophoresis; Embryo, Nonmammalian; Fishes; Gels; Genetic Code; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
Mental retardation, abnormal hair and mild aminoaciduria, all of unknown aetiology, in siblings.
Topics: Alanine; Child, Preschool; Female; Fluoroscopy; Glutamine; Glycine; Hair; Humans; Intellectual Disability; Male; Renal Aminoacidurias; Serine; Taurine | 1969 |
Isolation of a glycopeptide from a 7S protein in soybean globulins.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Globulins; Glucosamine; Glutamates; Glycine; Glycine max; Glycoproteins; Mannose; Molecular Weight; Monosaccharides; Polysaccharides; Serine; Threonine | 1969 |
Effectiveness of various sources of nonessential nitrogen in promoting growth of chicks fed carbohydrate-containing and "carbohydrate-free" diets.
Topics: Acetates; Alanine; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Cellulose; Chickens; Citrates; Diet; Dietary Carbohydrates; Glutamates; Glycine max; Growth; Male; Nitrogen; Nutritional Requirements; Oils; Plant Proteins; Quaternary Ammonium Compounds; Serine; Starch; Stereoisomerism; Zea mays | 1969 |
The specificity of purified porcine pancreatic elastase.
Topics: Alanine; Animals; Chromatography; Cysteine; Electrophoresis; Glutamates; Glycine; Histidine; Insulin; Leucine; Pancreas; Pancreatic Elastase; Phenylalanine; Serine; Swine; Valine | 1969 |
Stereochemical specificity of neutral amino acid transfer systems in rat small intestine.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Carbon Isotopes; Cysteine; Hydroxyproline; Ileum; Intestine, Small; Jejunum; Leucine; Methionine; Pipecolic Acids; Proline; Rats; Sarcosine; Serine; Stereoisomerism | 1969 |
[14CO2 biosynthesis from [3-14C]serine in red blood cells].
Topics: Alanine; Aldehydes; Animals; Autoradiography; Azoles; Carbon Dioxide; Carbon Isotopes; Catalase; Chromatography; Coenzyme A; Erythrocytes; Folic Acid; Formates; Ketoglutaric Acids; Lactates; Porphyrins; Rabbits; Reticulocytes; Serine; Succinates | 1969 |
Glycine synthesis and isocitrate lyase in the nematode, Caenorhabditis briggsae.
Topics: Acetates; Alanine; Animals; Aspartic Acid; Chromatography, Paper; Dinitrophenols; Glycine; Hydrazines; In Vitro Techniques; Lyases; Nematoda; Serine | 1964 |
End product control of amino acid synthesis by cultured human cells.
Topics: Alanine; Arginine; Culture Techniques; Enzyme Repression; Glucose; Glutamine; Glycine; Humans; Methionine; Ornithine; Proline; Serine | 1965 |
A method for the determination of free plasma amino acids in ultra-micro quantities.
Topics: Alanine; Amino Acids; Blood Chemical Analysis; Electrophoresis; Histidine; Humans; In Vitro Techniques; Leucine; Microchemistry; Ornithine; Radiotherapy; Serine; Threonine; Urine; Valine | 1965 |
[RNA isolated from turnip yellow mosaic virus; acceptor of amino acids in the presence of bacterial enzymes].
Topics: Alanine; Alcaligenes; Amino Acids; Arginine; In Vitro Techniques; Isoleucine; Leucine; Nucleotides; Phenylalanine; Plant Viruses; Proline; RNA, Viral; Serine; Ultracentrifugation; Valine | 1965 |
Stimulation of the binding of aminoacyl-sRNA to ribosomes by tubercidin (7-deazaadenosine) and N 6-dimethyladenosine containing trinucleoside diphosphate analogs.
Topics: Alanine; Anti-Bacterial Agents; Glutamates; Glycine; In Vitro Techniques; Lysine; Nucleotides; Proline; Ribosomes; RNA, Transfer; Serine; Threonine | 1965 |
Partial sequence of the first nine amino acids from the C-terminal end in bovine growth hormone.
Topics: Alanine; Amides; Amino Acid Sequence; Animals; Carboxypeptidases; Cattle; Chromatography, Paper; Glutamates; Glycine; Growth Hormone; In Vitro Techniques; Phenylalanine; Serine; Trypsin | 1965 |
Arginine and urea biosynthesis in the land planarian: its significance in biochemical evolution.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoradiography; Carbon Dioxide; Chromatography, Paper; Citrulline; Glutamates; Glutamine; Glycine; Serine; Succinates; Turbellaria; Urea | 1965 |
[Glutamate metabolism in rabbit renal cortex slices].
Topics: Alanine; Animals; Aspartic Acid; Autoradiography; Carbon Isotopes; Chromatography; Culture Techniques; Glucose; Glutamates; Glutamine; Glycine; Kidney; Rabbits; Serine | 1965 |
Regulation of amino acid accumulation in isolated rat diagphragm: effect of puromycin and insulin.
Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Isotopes; Cystine; Diaphragm; Histidine; In Vitro Techniques; Insulin; Isoleucine; Leucine; Male; Muscles; Phenylalanine; Proteins; Puromycin; Rats; Serine; Tryptophan; Tyrosine | 1965 |
The determination of amino acids in 0.1 ml. of blood plasma.
Topics: Alanine; Amino Acids; Arginine; Blood Chemical Analysis; Chemistry, Clinical; Chromatography, Gel; Chromatography, Paper; Colorimetry; Densitometry; Glutamine; Glycine; Humans; In Vitro Techniques; Lysine; Microchemistry; Serine; Taurine; Threonine; Valine | 1966 |
The enzymatic synthesis of N-methylglutamic acid.
Topics: Alanine; Amines; Ammonia; Aspartic Acid; Autoradiography; Chromatography, Paper; Dialysis; Glutamate Dehydrogenase; Glutamates; Glycine; In Vitro Techniques; Pseudomonas; Serine; Soil Microbiology | 1966 |
Amino acids in seven species of cestodes.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cestoda; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Nitrogen; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Amino acid compostion of walls from single and filamentous cells of Clostridium acidiurici.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacterial Proteins; Cell Wall; Chromatography; Clostridium; Glutamates; Glycine; In Vitro Techniques; Isomerases; Leucine; Lysine; Methionine; Oxidoreductases; Phenylalanine; Proline; Serine; Valine | 1966 |
Fractionation of amino acid-specific s-RNA from silkgland by methylated albumin column chromatography.
Topics: Alanine; Albumins; Animals; Bombyx; Chemical Phenomena; Chemistry; Chemistry Techniques, Analytical; Chromatography; Glycine; In Vitro Techniques; Leucine; Lysine; Methionine; Phenylalanine; RNA, Transfer; Serine; Tyrosine | 1966 |
Free amino acid pools in the developing sea urchin Lytechinus variegatus.
Topics: Alanine; Amino Acids; Animals; Echinodermata; Glycine; Serine | 1966 |
The occurrence of certain D-amino acids in insects.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Bombyx; Chromatography, Paper; Electrophoresis; Insecta; Serine | 1966 |
Isolation of amino acyl oligonucleotides from T-1 ribonuclease digests of soluble ribonucleic acid charged with serine, glycine, threonine, and alanine.
Topics: Alanine; Chromatography, Ion Exchange; Electrophoresis; Glycine; Nucleotides; Ribonucleases; RNA, Transfer; Saccharomyces; Serine; Threonine | 1966 |
On the synthesis of taurine from sulfate by the chick. I. Influential dietary factors.
Topics: Alanine; Amino Alcohols; Animals; Cysteine; Diet; Glycine; In Vitro Techniques; Kidney; Liver; Myocardium; Poultry; Pyruvates; Serine; Spleen; Sulfates; Sulfites; Taurine; Thiosulfates | 1966 |
Polyamide layer chromatography of DNP-amino acids.
Topics: Alanine; Amides; Arginine; Aspartic Acid; Chromatography; Dinitrophenols; Glutamates; Glycine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
Changes in the concentration of free amino acids in the rat brain during postnatal development.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Animals, Newborn; Aspartic Acid; Brain; Female; Glutamates; Glutamine; Glutathione; Glycine; Male; Rats; Serine; Taurine | 1966 |
Water relations of Salmonella oranienburg; stimulation of respiration by amino acids.
Topics: Alanine; Asparagine; Aspartic Acid; Carbon Isotopes; Culture Media; Cysteine; Glucose; Glutamine; Glycine; Methionine; Oxygen Consumption; Proline; Salmonella; Serine; Threonine; Water | 1966 |
Amino acid transport in the goldfish intestine.
Topics: Alanine; Animals; Biological Transport, Active; Fishes; Histidine; Intestinal Mucosa; Leucine; Methionine; Phenylalanine; Serine; Threonine; Valine | 1966 |
The amino acid sequence of the serine containing murein of Butybacterium Rettgeri.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Cell Wall; Chromatography, Paper; Eubacterium; Glucosamine; Glutamates; Lysine; Mucoproteins; Ornithine; Serine | 1966 |
Gas chromatographic separation of DNP amino acids and its application to the analysis of serum amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Cholesterol; Chromatography, Gas; Glutamates; Glycine; Hydroxyproline; Indicators and Reagents; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Valine | 1966 |
Nuclear histones and early embryogenesis of the chick.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Cell Division; Cell Nucleus; Chick Embryo; Electrophoresis; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Indications for a common evolutionary origin shown in the primary structure of three transfer RNAs.
Topics: Alanine; Biological Evolution; Chemical Phenomena; Chemistry; Genetic Code; RNA, Transfer; Serine; Tyrosine; Yeasts | 1966 |
Analysis of N-methylamino acids by automatic amino acid analyzer and gas-liquid chromatography.
Topics: Alanine; Anti-Bacterial Agents; Arginine; Aspartic Acid; Autoanalysis; Chromatography, Gas; Cysteine; Cystine; Glutamates; Glycine; Indicators and Reagents; Isoleucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1966 |
Incorporation of 14C from glucose into alpha-keto acids and amino acids in rat brain and liver in vivo.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Glucose; Glutamates; Glutamine; Glutarates; Glycine; Keto Acids; Liver; Male; Pyruvates; Rats; Serine | 1966 |
Studies on the growth of Prymnesium parvum Carter (chrysomonadina) and on the formation of its toxin (prymnesin).
Topics: Alanine; Eukaryota; Glycerol; Glycine; Light; Serine; Toxins, Biological | 1966 |
[Composition of the amino acid pool of Neurospora in deficiency of growth substance].
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Biotin; Choline; Chromatography, Ion Exchange; Culture Media; Glutamates; Glycine; Growth Inhibitors; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Pyridoxine; Riboflavin; Serine; Threonine; Tyrosine; Valine | 1966 |
[The influence of temperature on the content of some carbohydrates and amino acids in Spirogyra].
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Carbohydrate Metabolism; Chromatography, Paper; Eukaryota; Fructose; Glucose; Glutamates; Glutamine; Leucine; Nitrogen; Serine; Starch; Temperature; Valine | 1966 |
[On the structure of protamine. VII. On the effect of the age of the fishes on the composition of their protamine].
Topics: Age Factors; Alanine; Amino Acids; Animals; Arginine; Fishes; Glutamates; Proline; Protamines; Serine; Threonine; Tyrosine; Valine | 1966 |
[Incorporation of C14- and H3-tryptophan into different serum proteins through the perfused isolated normal and irradiated liver].
Topics: Alanine; Albumins; Amino Acids; Animals; Blood Proteins; Carbon Isotopes; Chromatography; Electrophoresis; Globulins; Glycine; Liver; Perfusion; Phenylalanine; Radiation Effects; Rats; Serine; Tritium; Tryptophan | 1966 |
[Composition and properties of the preparations isolated from Act. coelicolor with the aid of beta-naphtol].
Topics: Acetates; Actinomyces; Alanine; Arginine; Aspartic Acid; Chromatography, Paper; Cysteine; Glucosamine; Glutamates; Glycerol; Leucine; Lysine; Naphthalenes; Peptides; Phosphates; Ribose; Serine; Valine | 1966 |
[Quantitative changes in amino acids in grapes at different ripening stages].
Topics: Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Chromatography, Ion Exchange; Fruit; Glutamates; Serine; Threonine; Valine | 1966 |
[Chromatographic investigation of free amino acids of the heart, kidneys and brain in experimental myocarditis].
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Brain; Chromatography, Paper; Cystine; Glutamine; Glycine; Histidine; Kidney; Lysine; Methionine; Myocarditis; Myocardium; Phenylalanine; Rabbits; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
The occurrence of hypotaurine and other sulfur-containing amino acids in seminal plasma and spermatozoa of boar, bull and dog.
Topics: Alanine; Amino Acids; Animals; Asparagine; Cattle; Dogs; Electrophoresis; Glutamates; Glycine; In Vitro Techniques; Leucine; Male; Semen; Serine; Spermatozoa; Swine; Taurine; Valine | 1966 |
Free amino acids of human foetal and adult liver.
Topics: Adult; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Cystine; Female; Fetus; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1966 |
[Study of amino acid compositiion of basic polypeptides of animal origin by paper chromatography method].
Topics: Alanine; Amino Acids; Animals; Arginine; Brain Chemistry; Cattle; Chromatography, Paper; Cystine; Glutamates; Glycine; Histidine; Humans; Kidney; Liver; Lysine; Peptides; Phenylalanine; Placenta; Serine; Tryptophan; Valine | 1966 |
The effect of a nutritional pyridoxine deficiency on free amino acids and related substances in mouse brain.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Brain Chemistry; Chromatography, Ion Exchange; Diet; Glycine; In Vitro Techniques; Methionine; Mice; Serine; Urea; Vitamin B 6 Deficiency | 1967 |
Pyruvate metabolism in thiamine-deficient calves.
Topics: Alanine; Animals; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Cattle; Coenzyme A; Glutamates; Glycine; Lactates; Liver; Pyruvates; Serine; Thiamine Deficiency | 1967 |
Cell wall constituents of Leuconostoc citrovorum and Leuconostoc mesenteroides.
Topics: Alanine; Amino Acids; Amino Sugars; Autoanalysis; Carbohydrates; Cell Wall; Glucosamine; Glucose; Glutamates; Glycerol; Leuconostoc; Lysine; Rhamnose; Serine | 1967 |
Renal metabolism of alanine.
Topics: Alanine; Ammonia; Animals; Dogs; Glomerular Filtration Rate; Glutamates; Glutamine; Glycine; Ketoglutaric Acids; Kidney; Kidney Tubules; Oxidation-Reduction; Pyruvates; Serine; Threonine | 1967 |
Free amino acids in gamma-irradiated carrots.
Topics: Acetates; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Carbon Isotopes; Glutamates; Leucine; Methionine; Plants, Edible; Proline; Radiation Effects; Serine; Threonine; Tyrosine | 1967 |
Studies on phosphoserine aminotransferase of sheep brain.
Topics: Alanine; Animals; Brain; Chromatography; Glutamates; In Vitro Techniques; Kinetics; Molecular Weight; Phosphates; Serine; Sheep; Transaminases; Ultracentrifugation | 1967 |
Oligonucleoides from yeast tyrosine transfer ribonucleic acid.
Topics: Alanine; Chromatography; Nucleotides; Ribonucleases; RNA, Transfer; Serine; Spectrophotometry; Tyrosine; Yeasts | 1967 |
Further studies of amino acid transport by embryonic chick bone.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Bone and Bones; Chick Embryo; Dactinomycin; Ethylmaleimide; Glycine; In Vitro Techniques; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Comparison of the carbohydrate and amino acid composition of bovine, ovine and human luteinizing hormone.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cattle; Galactose; Glucosamine; Glutamates; Hexosamines; Hexoses; Humans; In Vitro Techniques; Luteinizing Hormone; Lysine; Mannose; Neuraminic Acids; Proline; Serine; Sheep; Threonine; Valine | 1967 |
The metabolism of triglycerides by spores of Penicillium roqueforti.
Topics: Alanine; Azides; Chloramphenicol; Dinitrophenols; Enzymes; Esterases; Glycerides; Isoflurophate; Ketones; Oxygen Consumption; Penicillium; Phosphates; Proline; Serine; Spores; Triglycerides | 1967 |
Effects of cortisol and 19-nortestosterone on the free amino acid pools and amino acid uptake of cultured cells.
Topics: Alanine; Amino Acids; Aspartic Acid; Biological Transport; Carbon Isotopes; Culture Techniques; Glycine; HeLa Cells; Hydrocortisone; Nandrolone; Neoplasms, Experimental; Serine; Threonine | 1967 |
Synthesis and properties of some N-pyridoxyl-L-amino acids and N-(5-phosphopyridoxyl)-L-amino acids.
Topics: Alanine; Aldehydes; Arginine; Aspartic Acid; Chemistry, Organic; Chromatography, Paper; Glutamates; Organic Chemistry Phenomena; Pyridines; Pyridoxal Phosphate; Pyrrolidinones; Serine; Tryptophan; Tyrosine | 1967 |
The recovery of amino acids from acid hydrolysates of whole urine from patients with thermal burns.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Burns; Creatine; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1967 |
The influence of medium composition on the growth and swarming of Proteus.
Topics: Alanine; Asparagine; Aspartic Acid; Culture Media; Glutamates; Glutamine; Proline; Proteus; Serine | 1967 |
The utilization of D-amino acids by yeasts.
Topics: Alanine; Amino Acids; Candida; Cryptococcus; Glutamates; Proline; Saccharomyces; Serine; Sewage; Soil Microbiology; Water Microbiology; Yeasts | 1967 |
Urinary amino acids of rats receiving high sugar diets.
Topics: Alanine; Alcohols; Amino Acids; Animals; Arabinose; Ascorbic Acid; Asparagine; Aspartic Acid; Dietary Carbohydrates; Female; Galactose; Glucose; Glutamates; Glycine; Inositol; Intestines; Neomycin; Rats; Ribose; Serine; Taurine; Threonine; Xylitol; Xylose | 1967 |
Glucose repression of oxidation of organic compounds by Sphaerotilus.
Topics: Acetates; Alanine; Culture Media; Enzyme Repression; Glucose; Glutamates; Gram-Negative Aerobic Bacteria; Pyruvates; Serine | 1967 |
Electron microscopic and biochemical characterization of collagen in blattarian insects.
Topics: Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Collagen; Connective Tissue Cells; Cysteine; Cystine; Female; Glutamates; Glycine; Histidine; Histocytochemistry; Hydroxyproline; Insecta; Isoleucine; Leucine; Lysine; Male; Methionine; Microscopy, Electron; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1967 |
Rapid short-column chromatography of amino acids. A method for blood and urine specimens in the diagnosis and treatment of metabolic disease.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Aminobutyrates; Autoanalysis; Buffers; Chromatography, Ion Exchange; Citrates; Cysteine; Cystine; Glutamates; Glutamine; Glycine; Humans; Hydrogen-Ion Concentration; Hydroxyproline; Isoleucine; Phenylalanine; Proline; Sarcosine; Serine; Threonine; Tyrosine; Valine | 1967 |
Concentrations of free glucogenic amino acids in livers of rats subjected to various metabolic stresses.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Diabetes Mellitus, Experimental; Gluconeogenesis; Glutamates; Glutamine; Hypoxia; Insulin; Liver; Male; Phlorhizin; Rats; Serine; Starvation; Threonine; Transaminases | 1967 |
Gluconeogenesis from amino acids in neonatal rat liver.
Topics: Alanine; Alanine Transaminase; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartate Aminotransferases; Aspartic Acid; Gluconeogenesis; Glutamates; Glycine; Histidine; In Vitro Techniques; Leucine; Liver; Liver Glycogen; Phenylalanine; Proline; Rats; Serine; Spectrophotometry; Threonine; Tyrosine; Valine | 1967 |
Requirements for growth of Streptococcus agalactiae in a chemically defined medium.
Topics: Alanine; Ascorbic Acid; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Proline; Serine; Streptococcus; Thioglycolates | 1967 |
The influence of nitrogenous compounds on growth of Pythium species.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Cysteine; Fungi; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Nitrates; Nitrites; Nitrogen; Peptones; Quaternary Ammonium Compounds; Serine; Succinates; Threonine; Yeast, Dried | 1967 |
Optical rotatory dispersion. XL. Protected derivatives of the tri- and tetra-peptides of alanine and serine.
Topics: Alanine; Peptides; Serine | 1967 |
A distinct Na+-requiring transport system for alanine, serine, cysteine, and similar amino acids.
Topics: Alanine; Amino Acids; Animals; Carcinoma, Ehrlich Tumor; Cysteine; Depression, Chemical; Kinetics; Radiation Effects; Serine; Sodium | 1967 |
[The amino acid sequence of the serine-containing mureins of Lactobacillus viridescens and Leuconostoc].
Topics: Alanine; Amino Acid Sequence; Amino Acids; Amino Sugars; Chromatography, Paper; Glutamates; Lactobacillus; Leuconostoc; Lysine; Models, Structural; Peptides; Polysaccharides, Bacterial; Protein Hydrolysates; Serine | 1967 |
Effect of amino acids on zinc-65 incorporation by Ehrlich ascites tumor cells in vitro.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Female; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Lysine; Methionine; Mice; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Zinc; Zinc Isotopes | 1967 |
On the uptake of nystatin by saccharomyces cerevisiae. 5 The release of amino acids.
Topics: Alanine; Amino Acids; Calcium; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Nystatin; Saccharomyces cerevisiae; Serine; Sterols; Temperature | 1982 |
Study of the relationship between free amino acids and cataract in human lenses.
Topics: Adult; Aged; Alanine; Amino Acids; Cataract; Glutamates; Glutamic Acid; Glycine; Humans; Lens, Crystalline; Leucine; Middle Aged; Serine; Threonine | 1984 |
Symmetrical distribution of amino acid neurotransmitters in the right and left cerebral cortex of the rat.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Glycine; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Threonine; Tissue Distribution | 1984 |
Studies of peptide antibiotics. XLIII. Syntheses of gramicidin S analogs containing D-serine or dehydroalanine in place of D-phenylalanine and asymmetric hydrogenation of the dehydroalanine residue.
Topics: Alanine; Bacteria; Gramicidin; Indicators and Reagents; Optical Rotation; Phenylalanine; Serine; Structure-Activity Relationship | 1983 |
Transport of neutral amino acids by adult articular cartilage.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Binding, Competitive; Biological Transport, Active; Cartilage, Articular; Cattle; Hydrogen-Ion Concentration; Kinetics; Leucine; Male; Serine; Sodium; Substrate Specificity | 1983 |
Control of hepatic utilization of serine, glycine and threonine in fed and starved rats.
Topics: Alanine; Alanine Transaminase; Animals; Dietary Carbohydrates; Dietary Proteins; Gluconeogenesis; Glycine; L-Serine Dehydratase; Lactates; Lactic Acid; Liver; Male; Rats; Serine; Starvation; Threonine | 1983 |
Alanine-resistant mutants of Chinese hamster ovary cells, CHO-K1, producing increases in velocity of proline transport through the A, ASC, and P systems.
Topics: Alanine; Animals; Biological Transport; Cell Line; Cricetinae; Cricetulus; Drug Resistance; Female; Glutamine; Kinetics; Mutation; Ovary; Proline; Serine | 1983 |
[Electrophysiological study of olfactory sensitivity in the carp].
Topics: Alanine; Amino Acids; Animals; Carps; Cyprinidae; Dose-Response Relationship, Drug; Evoked Potentials, Somatosensory; In Vitro Techniques; Olfactory Nerve; Sensory Thresholds; Serine; Stimulation, Chemical; Valine | 1983 |
Biochemical studies of olfaction: binding specificity of odorants to a cilia preparation from rainbow trout olfactory rosettes.
Topics: Alanine; Animals; Binding, Competitive; Central Nervous System; Cilia; Kinetics; Odorants; Olfactory Pathways; Sensory Receptor Cells; Serine; Smell; Threonine; Tritium; Trout | 1983 |
Precursor of carbon atom five and hydroxymethyl carbon atom of the pyrimidine moiety of thiamin in Escherichia coli.
Topics: Alanine; Escherichia coli; Glycerol; Pyrimidines; Pyruvates; Pyruvic Acid; Ribonucleotides; Serine; Thiamine | 1983 |
Amino acid precursors of Myxococcus xanthus antibiotic TA.
Topics: Acetates; Alanine; Amino Acids; Anti-Bacterial Agents; Carbon Radioisotopes; Glycine; Macrolides; Myxococcales; Serine | 1983 |
How signal sequences maintain cleavage specificity.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Endopeptidases; Eukaryotic Cells; Glycine; Membrane Proteins; Peptides; Prokaryotic Cells; Protein Sorting Signals; Serine; Serine Endopeptidases | 1984 |
Amino acid transport in human tonsillar lymphocytes with regard to patient's age and tonsillar diseases.
Topics: Adult; Age Factors; Alanine; Amino Acids; Arthritis, Rheumatoid; B-Lymphocytes; Biological Transport; Child; Child, Preschool; Glutamine; Humans; Lymphocytes; Lysine; Palatine Tonsil; Phenylalanine; Recurrence; Serine; T-Lymphocytes; Tonsillitis | 1984 |
Independent plasma levels of sodium and glycine during transurethral resection of the prostate.
Topics: Aged; Alanine; Animals; Blood Glucose; Dogs; Glycine; Humans; Hyponatremia; Intraoperative Complications; Male; Osmolar Concentration; Prostatectomy; Serine | 1984 |
Acetyl-blocked N-terminal structures of sorbitol and aldehyde dehydrogenases.
Topics: Acetylation; Alanine; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Endopeptidases; Gas Chromatography-Mass Spectrometry; Humans; L-Iditol 2-Dehydrogenase; Liver; Mass Spectrometry; Peptide Fragments; Serine; Sheep; Sugar Alcohol Dehydrogenases | 1984 |
Amino acid metabolism in the brain with convulsive disorders. Part I: Free amino acid patterns in the brain of E1 mouse with convulsive seizure.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Cystathionine; gamma-Aminobutyric Acid; Glutamine; Mice; Mice, Inbred Strains; Ornithine; Seizures; Serine | 1984 |
Conversion of glycerate to serine in intact spinach leaf peroxisomes.
Topics: Alanine; Alcohol Oxidoreductases; Biotransformation; Chemical Phenomena; Chemistry; Glyceric Acids; Hydrogen-Ion Concentration; Hydroxypyruvate Reductase; Kinetics; Microbodies; NAD; Oxaloacetates; Plants; Serine | 1984 |
Neutral amino acid transport and in vitro aging.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport; Cell Line; Cell Survival; Culture Media; Fibroblasts; Humans; Kinetics; Phenylalanine; Serine; Threonine | 1984 |
Inactivation of the Pseudomonas striata broad specificity amino acid racemase by D and L isomers of beta-substituted alanines: kinetics, stoichiometry, active site peptide, and mechanistic studies.
Topics: Alanine; Amino Acid Isomerases; Amino Acids; beta-Alanine; Binding Sites; Borates; Isomerism; Kinetics; Molecular Weight; NAD; Pseudomonas; Pyridoxal Phosphate; Serine; Trypsin | 1984 |
Plasma amino acids in 3/sec spike-wave epilepsy.
Topics: Adolescent; Adult; Alanine; Amino Acids; Aspartic Acid; Child; Child, Preschool; Epilepsy; Female; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Male; Methionine; Middle Aged; Phenylalanine; Serine; Taurine; Threonine; Tyrosine; Valine | 1980 |
Transition state affinity jump chromatography. A double selection method for isolating catalytically active enzymes and other molecules.
Topics: Alanine; Chromatography, Affinity; Chymotrypsin; Enzymes, Immobilized; Serine; Tritium | 1980 |
Effects of central administration of alanine on body temperature of the rabbit: comparisons with the effects of serine, glycine and taurine.
Topics: Alanine; Animals; Bacterial Toxins; Body Temperature Regulation; Endotoxins; Enterotoxins; Glycine; Injections, Intraventricular; Interleukin-1; Male; Prostaglandins E; Proteins; Rabbits; Serine; Taurine | 1981 |
Amino acid transport via the red cell anion transport system.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Alanine; Amino Acids; Biological Transport; Carrier Proteins; Cysteine; Depression, Chemical; Erythrocytes; Glycine; Humans; In Vitro Techniques; Proline; Serine; Threonine; Valine | 1981 |
Use of isotope effects and pH studies to determine the chemical mechanism of Bacillus subtilis L-alanine dehydrogenase.
Topics: Alanine; Alanine Dehydrogenase; Amino Acid Oxidoreductases; Bacillus subtilis; Chemical Phenomena; Chemistry, Physical; Deuterium; Hydrogen-Ion Concentration; Mathematics; NAD; Serine | 1981 |
Effect of non-essential amino acids on fetal rat pancreatic growth and insulin secretion in vitro.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Glycine; Insulin; Insulin Secretion; Organ Culture Techniques; Pancreas; Proline; Rats; Rats, Inbred Strains; Serine | 1981 |
The identification of phosphoseryl residues during the determination amino acid sequence in phosphoproteins.
Topics: Alanine; Amino Acid Sequence; Chemical Phenomena; Chemistry; Isothiocyanates; Phosphoproteins; Phosphoserine; Serine; Thiocyanates | 1982 |
The transport of alanine, serine, and cysteine in cultured human fibroblasts.
Topics: Alanine; Amino Acids; Amino Acids, Cyclic; Aminoisobutyric Acids; Biological Transport; Cells, Cultured; Cysteine; Fibroblasts; Humans; Kinetics; Serine; Sodium | 1982 |
Compounds protective against renal tubular necrosis induced by D-serine and D-2,3-diaminopropionic acid in the rat.
Topics: Acute Kidney Injury; Alanine; Amino Acids; Animals; beta-Alanine; Kidney Tubular Necrosis, Acute; Rats; Rats, Inbred Strains; Serine; Stereoisomerism | 1982 |
Unidirectional uptake of L-alanine and L-serine by system ASC in the basolateral membrane of cat salivary epithelium. Selective inhibition of rapid alanine metabolism by aminooxyacetate.
Topics: Acetates; Alanine; Aminooxyacetic Acid; Animals; Biological Transport, Active; Cats; Cell Membrane; Epithelium; Female; In Vitro Techniques; Male; Perfusion; Serine; Submandibular Gland | 1982 |
A sodium-indpendent low affinity transport system for neutral amino acids in rabbit ileal mucosa.
Topics: Alanine; Animals; Autoradiography; Biological Transport; Ileum; In Vitro Techniques; Intestinal Mucosa; Kinetics; Methionine; Rabbits; Serine; Sodium | 1980 |
Decreased cysteine and proline synthesis in parenterally fed, premature infants.
Topics: Alanine; Amino Acids; Aspartic Acid; Birth Weight; Blood Glucose; Carbon Isotopes; Cysteine; Electrolytes; Energy Intake; Female; Food, Formulated; Gas Chromatography-Mass Spectrometry; Gestational Age; Glucose; Glutamic Acid; Glycine; Humans; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Lipids; Male; Parenteral Nutrition; Parenteral Nutrition Solutions; Proline; Serine; Solutions | 1995 |
Use of protease sensitivity to probe the conformations of newly synthesised mutant forms of mitochondrial aspartate aminotransferase.
Topics: Alanine; Animals; Aspartate Aminotransferases; Cell-Free System; Cysteine; Kinetics; Mitochondria, Liver; Mutagenesis, Site-Directed; Plasmids; Point Mutation; Pronase; Protein Conformation; Rats; Recombinant Fusion Proteins; Serine; Tetrahydrofolate Dehydrogenase | 1995 |
Role of CD4 endocytosis in human immunodeficiency virus infection.
Topics: Alanine; Amino Acid Sequence; CD4 Antigens; Endocytosis; HeLa Cells; HIV-1; HIV-2; Humans; Hypertonic Solutions; Mutagenesis, Site-Directed; Point Mutation; Recombinant Proteins; Serine; Transfection | 1995 |
Binding of phenylarsenoxide to Arg-tRNA protein transferase is independent of vicinal thiols.
Topics: Acyltransferases; Alanine; Aminoacyltransferases; Arsenicals; Base Sequence; Cysteine; DNA Primers; Iodine Radioisotopes; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Saccharomyces cerevisiae; Serine; Sulfhydryl Compounds | 1995 |
NMDA receptor channels: subunit-specific potentiation by reducing agents.
Topics: Alanine; Animals; Base Sequence; Cell Line; Cloning, Molecular; Cysteine; Dithiothreitol; Drug Synergism; Ethylmaleimide; Glutamates; Glutamic Acid; Glutathione; Humans; Ion Channels; Kidney; Kinetics; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Serine; Transfection | 1994 |
An RNA binding site in a tRNA synthetase with a reduced set of amino acids.
Topics: Acylation; Alanine; Amino Acid Sequence; Anticodon; Binding Sites; Escherichia coli; Methionine-tRNA Ligase; Molecular Sequence Data; Protein Conformation; RNA; Serine | 1994 |
A unique amino acid of the Drosophila GABA receptor with influence on drug sensitivity by two mechanisms.
Topics: Alanine; Animals; Binding Sites; Cells, Cultured; Dieldrin; Dose-Response Relationship, Drug; Drosophila; Hexachlorocyclohexane; Insecticide Resistance; Insecticides; Mutation; Neurons; Picrotoxin; Receptors, GABA; Serine | 1994 |
Identification of the major sites of phosphorylation in IGF binding protein-3.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Carrier Proteins; CHO Cells; Cricetinae; DNA Primers; Glycosylation; Humans; Insulin-Like Growth Factor Binding Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphates; Phosphorylation; Point Mutation; Polymerase Chain Reaction; Proinsulin; Protein Kinases; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Transfection | 1994 |
Identification of three proline-directed phosphorylation sites in the human androgen receptor.
Topics: Alanine; Animals; Binding Sites; Humans; Mutation; Phosphorylation; Proline; Receptors, Androgen; Sequence Deletion; Serine; Structure-Activity Relationship; Transcription, Genetic | 1995 |
Replacements of histidine 226 of NhaA-Na+/H+ antiporter of Escherichia coli. Cysteine (H226C) or serine (H226S) retain both normal activity and pH sensitivity, aspartate (H226D) shifts the pH profile toward basic pH, and alanine (H226A) inactivates the ca
Topics: Alanine; Aspartic Acid; Codon; Cysteine; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Phenotype; Point Mutation; Serine; Sodium-Hydrogen Exchangers | 1995 |
A catalytic mechanism for the dual-specific phosphatases.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Catalysis; Consensus Sequence; Conserved Sequence; Iodoacetates; Iodoacetic Acid; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphoric Monoester Hydrolases; Point Mutation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Substrate Specificity; Vaccinia virus; Viral Proteins | 1995 |
DNA sequence and site of mutation of the GABA receptor of cyclodiene-resistant red flour beetle, Tribolium castaneum.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Cockroaches; Drosophila melanogaster; Insecticide Resistance; Insecticides; Molecular Sequence Data; Mutagenesis; Mutation; Polymerase Chain Reaction; Rats; Receptors, GABA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Serine; Tribolium | 1995 |
Cumulative effects of mutations in newly synthesised mitochondrial aspartate aminotransferase on uptake into mitochondria.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartate Aminotransferases; Cysteine; Kinetics; Mitochondria; Mutagenesis, Site-Directed; Point Mutation; Protein Processing, Post-Translational; Recombinant Proteins; Serine | 1995 |
Identification of the sites of phosphorylation in insulin-like growth factor binding protein-1. Regulation of its affinity by phosphorylation of serine 101.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Growth Hormone; Humans; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor I; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Peptide Fragments; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Recombinant Proteins; Serine; Transfection | 1993 |
Human IGFBP-1 is phosphorylated on 3 serine residues: effects of site-directed mutagenesis of the major phosphoserine.
Topics: Alanine; Amino Acid Sequence; Animals; Carrier Proteins; CHO Cells; Cricetinae; Humans; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor I; Liver Neoplasms, Experimental; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Phosphoserine; Protein Binding; Serine; Tumor Cells, Cultured | 1993 |
Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by negative charge in the R domain.
Topics: Alanine; Amino Acid Sequence; Animals; Autoradiography; Cell Line; Chloride Channels; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; HeLa Cells; Humans; Ion Channel Gating; Ion Channels; Kinetics; Membrane Proteins; Methionine; Mutagenesis, Site-Directed; Peptide Mapping; Phosphopeptides; Phosphorylation; Protein Kinases; Serine; Sulfur Radioisotopes; Transfection | 1993 |
Impairment of muscle function caused by mutations of phosphorylation sites in myosin regulatory light chain.
Topics: Alanine; Animals; Calcium; Drosophila melanogaster; Isometric Contraction; Muscle, Skeletal; Mutagenesis, Site-Directed; Myosin-Light-Chain Kinase; Myosins; Phosphorylation; Serine | 1995 |
[Energetic and/or nitrogen underfeeding in the dry cow. Effects on volatile fatty acids in the rumen, some plasma metabolites and hormones and urinary excretion of 3-methylhistidine].
Topics: Alanine; Amino Acids; Animals; Blood Glucose; Cattle; Dietary Proteins; Energy Intake; Fatty Acids, Volatile; Female; Growth Hormone; Insulin; Methylhistidines; Nitrogen; Rumen; Serine; Time Factors; Urea | 1995 |
A mutation in an ATP-binding loop of Saccharomyces cerevisiae actin (S14A) causes a temperature-sensitive phenotype in vivo and in vitro.
Topics: Actins; Adenosine Triphosphate; Alanine; Base Sequence; Binding Sites; Genotype; Kinetics; Microscopy, Electron; Molecular Sequence Data; Mutagenesis, Site-Directed; Myosins; Oligodeoxyribonucleotides; Phenotype; Point Mutation; Recombinant Proteins; Saccharomyces cerevisiae; Serine; Temperature; Time Factors; Viscosity | 1995 |
The effect of the S14A mutation on the conformation and thermostability of Saccharomyces cerevisiae G-actin and its interaction with adenine nucleotides.
Topics: Actins; Adenosine Triphosphate; Alanine; Amino Acid Sequence; Animals; Binding Sites; Calcium; Drug Stability; Hot Temperature; Kinetics; Magnesium; Models, Structural; Muscle, Skeletal; Point Mutation; Protein Conformation; Protein Denaturation; Rabbits; Saccharomyces cerevisiae; Serine; Thermodynamics | 1995 |
Metabolic fates of carbon skeletons of methionine, serine, and alanine in growing rats fed soybean protein diets.
Topics: Alanine; Amino Acids; Animals; Carbon; Carbon Radioisotopes; Dietary Proteins; Lipid Metabolism; Liver; Male; Methionine; Plant Proteins, Dietary; Proteins; Rats; Rats, Wistar; Serine; Soybean Proteins; Weight Gain | 1994 |
Serine phosphorylation in the NH2 terminus of p53 facilitates transactivation.
Topics: Alanine; Animals; Aspartic Acid; Base Sequence; Binding Sites; Cell Nucleus; DNA; Gene Expression; Mice; Molecular Sequence Data; Mutation; Phosphorylation; Rats; Sensitivity and Specificity; Serine; Transcriptional Activation; Transformation, Genetic; Tumor Suppressor Protein p53 | 1995 |
Electrospray-ionization mass spectrometry of molecular variants of a [2Fe-2S] ferredoxin.
Topics: Alanine; Apoproteins; Clostridium; Cysteine; Ferredoxins; Genetic Variation; Iron; Macromolecular Substances; Mass Spectrometry; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Serine; Sulfur | 1995 |
Mutational analysis of the putative substrate-binding site of 3C proteinase of coxsackievirus B3.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Conserved Sequence; DNA Primers; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enterovirus B, Human; Escherichia coli; Glycine; Histidine; Molecular Sequence Data; Mutation; Sequence Alignment; Serine; Threonine | 1995 |
Crystallographic analyses of NADH peroxidase Cys42Ala and Cys42Ser mutants: active site structures, mechanistic implications, and an unusual environment of Arg 303.
Topics: Alanine; Arginine; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Mutation; Peroxidases; Protein Structure, Tertiary; Serine | 1995 |
Mutagenesis studies of the phosphorylation sites of recombinant human pyruvate dehydrogenase. Site-specific regulation.
Topics: Alanine; Animals; Cattle; Escherichia coli; Humans; Mutagenesis, Site-Directed; Phosphorylation; Pyruvate Dehydrogenase Complex; Recombinant Proteins; Serine | 1995 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
An alanine29-serine variant in exon 2 of the low density lipoprotein receptor gene: no association with hypercholesterolemia.
Topics: Alanine; Base Sequence; Exons; Humans; Hypercholesterolemia; Molecular Sequence Data; Polymerase Chain Reaction; Receptors, LDL; Serine | 1994 |
Site-directed mutagenesis of vacuolar H(+)-pyrophosphatase. Necessity of Cys634 for inhibition by maleimides but not catalysis.
Topics: Alanine; Amino Acid Sequence; Arabidopsis; Base Sequence; Catalysis; Cysteine; DNA, Complementary; Ethylmaleimide; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyrophosphatases; Saccharomyces cerevisiae; Serine; Vacuoles | 1995 |
Cell cycle regulation of the p34cdc2/p33cdk2-activating kinase p40MO15.
Topics: 3T3 Cells; Alanine; Animals; Base Sequence; Cell Cycle; Cell Extracts; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Glutathione Transferase; Interphase; Mice; Molecular Sequence Data; Mutation; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Serine; Xenopus | 1994 |
Drosophila GABA-gated chloride channel: modified [3H]EBOB binding site associated with Ala-->Ser or Gly mutants of Rdl subunit.
Topics: Alanine; Animals; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Drosophila melanogaster; Drosophila Proteins; gamma-Aminobutyric Acid; Glycine; Insecticide Resistance; Ion Channel Gating; Muscimol; Mutation; Receptors, GABA-A; Serine; Structure-Activity Relationship; Tritium | 1995 |
Different sites of acivicin binding and inactivation of gamma-glutamyl transpeptidases.
Topics: Alanine; Amino Acid Sequence; Animals; Antimetabolites; Base Sequence; Binding Sites; Cloning, Molecular; DNA Primers; gamma-Glutamyltransferase; Humans; Hydroxylamine; Hydroxylamines; Isoxazoles; Kidney; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Point Mutation; Rats; Recombinant Proteins; Restriction Mapping; Serine; Swine; Threonine | 1995 |
Electrostatic activation of rat phenylalanine hydroxylase.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Cyclic AMP-Dependent Protein Kinases; DNA; Electrochemistry; Enzyme Activation; Glutamates; Glutamic Acid; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine Hydroxylase; Phosphorylation; Plasmids; Polymerase Chain Reaction; Rats; Recombinant Proteins; Restriction Mapping; Serine | 1994 |
Intrinsic primary, secondary, and solvent kinetic isotope effects on the reductive half-reaction of D-amino acid oxidase: evidence against a concerted mechanism.
Topics: Alanine; Catalysis; D-Amino-Acid Oxidase; Deuterium; Glycine; Kinetics; Serine; Solvents; Structure-Activity Relationship; Tritium | 1994 |
pH and kinetic isotope effects on the oxidative half-reaction of D-amino-acid oxidase.
Topics: Alanine; Animals; D-Amino-Acid Oxidase; Glycine; Hydrogen-Ion Concentration; Isotopes; Kinetics; Oxidation-Reduction; Rabbits; Serine; Substrate Specificity | 1994 |
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells.
Topics: 3T3 Cells; Alanine; Animals; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Neoplastic; Culture Media, Serum-Free; DNA; Enzyme Activation; Glutamates; Glutamic Acid; Mice; Mitogen-Activated Protein Kinase Kinases; Mutation; Neurites; Neurons; PC12 Cells; Protein Kinase Inhibitors; Protein Kinases; Serine; Signal Transduction | 1994 |
Site-directed mutagenesis and functional analysis of the active-site residues of the E2 component of bovine branched-chain alpha-keto acid dehydrogenase complex.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Alanine; Amino Acid Sequence; Animals; Binding Sites; Catalysis; Cattle; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Ketone Oxidoreductases; Kinetics; Molecular Sequence Data; Molecular Structure; Multienzyme Complexes; Mutagenesis, Site-Directed; Recombinant Proteins; Serine; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Substrate Specificity | 1994 |
Mutated forms of the [2Fe-2S] ferredoxin from Clostridium pasteurianum with noncysteinyl ligands to the iron-sulfur cluster.
Topics: Alanine; Base Sequence; Clostridium; Cysteine; DNA, Bacterial; Electron Spin Resonance Spectroscopy; Escherichia coli; Ferredoxins; Iron; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Serine; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Sulfur | 1994 |
Histidine ammonia-lyase mutant S143C is posttranslationally converted into fully active wild-type enzyme. Evidence for serine 143 to be the precursor of active site dehydroalanine.
Topics: Alanine; Base Sequence; Cysteine; Histidine Ammonia-Lyase; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxygen; Protein Precursors; Protein Processing, Post-Translational; Pseudomonas putida; Recombinant Proteins; Serine; Structure-Activity Relationship; Sulfhydryl Compounds; Threonine | 1994 |
In vivo conversion of L-serine to D-alanine in a ribosomally synthesized polypeptide.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Bacteriocins; Base Sequence; Cloning, Molecular; Lactobacillus; Molecular Sequence Data; Protein Processing, Post-Translational; Ribosomes; Serine; Stereoisomerism | 1994 |
Calcium-induced phosphorylation of ETS1 inhibits its specific DNA binding activity.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Calcium; Chickens; DNA; Ionomycin; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Peptide Fragments; Phosphopeptides; Phosphorylation; Proto-Oncogene Protein c-ets-1; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Receptors, Antigen, T-Cell; Recombinant Proteins; Serine; Substrate Specificity; Transcription Factors | 1994 |
An assessment of progression of brain edema with amino acid levels in cerebrospinal fluid and changes in electroencephalogram in an adult cat model of cold brain injury.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cats; Electroencephalography; Evoked Potentials; Freezing; Glutamic Acid; Methionine; Motor Cortex; Phenylalanine; Serine; Synaptic Transmission; Tyrosine; Valine | 1994 |
A spectroscopic study of the mitochondrial transit peptide of rat malate dehydrogenase.
Topics: Alanine; Amino Acid Sequence; Animals; Biological Transport, Active; Cardiolipins; Circular Dichroism; Computer Simulation; Lipid Bilayers; Magnetic Resonance Spectroscopy; Malate Dehydrogenase; Mitochondria; Molecular Sequence Data; Peptide Fragments; Peptides; Phosphatidylglycerols; Protein Structure, Secondary; Rats; Reference Standards; Serine; Spectroscopy, Fourier Transform Infrared; Trifluoroethanol | 1994 |
A mutant v-rel with increased ability to transform B lymphocytes.
Topics: Alanine; Amino Acid Sequence; Animals; B-Lymphocytes; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Chickens; DNA Primers; DNA-Binding Proteins; Molecular Sequence Data; Mutation; Oncogene Proteins v-rel; Retroviridae Proteins, Oncogenic; Serine | 1995 |
Stereoselective antagonism by enantiomers of alanine and serine of phencyclidine-induced hyperactivity, stereotypy and ataxia in the rat.
Topics: Alanine; Animals; Ataxia; Injections, Intraventricular; Male; Motor Activity; Phencyclidine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism; Stereotyped Behavior | 1994 |
Sequence analysis and expression studies of a gene encoding a novel serine + alanine-rich protein in Trichoderma harzianum.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Cloning, Molecular; DNA, Complementary; DNA, Fungal; Fungal Proteins; Genes, Fungal; Molecular Sequence Data; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serine; Trichoderma | 1994 |
Stability of o-phthalaldehyde-sulfite derivatives of amino acids and their methyl esters: electrochemical and chromatographic properties.
Topics: Alanine; Amino Acids; Arginine; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; o-Phthalaldehyde; Serine; Sulfites; Temperature | 1994 |
Site-directed mutagenesis of phosphorylation sites of the branched chain alpha-ketoacid dehydrogenase complex.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Alanine; Animals; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genetic Vectors; Glutamates; Ketone Oxidoreductases; Kinetics; Molecular Weight; Multienzyme Complexes; Mutagenesis, Site-Directed; Phosphorylation; Plasmids; Protein Kinases; Rats; Recombinant Proteins; Serine; Substrate Specificity | 1994 |
Serine-202 is the putative precursor of the active site dehydroalanine of phenylalanine ammonia lyase. Site-directed mutagenesis studies on the enzyme from parsley (Petroselinum crispum L.).
Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Blotting, Western; DNA; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine Ammonia-Lyase; Plants; Sequence Homology, Amino Acid; Serine | 1994 |
Replacement of serine 237 in class A beta-lactamase of Proteus vulgaris modifies its unique substrate specificity.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; beta-Lactamases; beta-Lactams; Escherichia coli; Glutamine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Proteus vulgaris; Sequence Analysis, DNA; Serine; Structure-Activity Relationship; Substrate Specificity | 1994 |
Residues interacting with serine-174 and alanine-295 in the beta-subunit of Escherichia coli H(+)-ATP synthase: possible ternary structure of the center region of the subunit.
Topics: Alanine; Base Sequence; Binding Sites; Escherichia coli; Molecular Sequence Data; Molecular Structure; Point Mutation; Proton-Translocating ATPases; Serine | 1994 |
Holoenzyme interaction sites in the cAMP-dependent protein kinase. Histidine 87 in the catalytic subunit complements serine 99 in the type I regulatory subunit.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Binding Sites; Chromatography, Gel; Cloning, Molecular; Cyclic AMP-Dependent Protein Kinases; Escherichia coli; Histidine; Kinetics; Macromolecular Substances; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Serine | 1994 |
Mutation Ala2-->Ser destabilizes intersubunit interactions in the molecular chaperone GroEL.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Chaperonin 10; Chaperonin 60; Escherichia coli; Heat-Shock Proteins; Kinetics; Macromolecular Substances; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Ribonucleotides; Serine | 1993 |
Feedback inhibition of fully unadenylylated glutamine synthetase from Salmonella typhimurium by glycine, alanine, and serine.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Chromatography, Affinity; Crystallization; Feedback; Fourier Analysis; Glutamate-Ammonia Ligase; Glycine; Kinetics; Models, Molecular; Protein Binding; Protein Conformation; Salmonella typhimurium; Serine; X-Ray Diffraction | 1993 |
Free D-serine, D-aspartate and D-alanine in central nervous system and serum in mutant mice lacking D-amino acid oxidase.
Topics: Alanine; Animals; Aspartic Acid; Brain Chemistry; Cerebellum; D-Amino-Acid Oxidase; Male; Mice; Mice, Mutant Strains; Serine; Stereoisomerism | 1993 |
The dopamine DA-1 receptor agonist fenoldopam enhances amino-acid-induced hyperemia in dogs.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Alanine; Amino Acids; Animals; Dogs; Dopamine Agents; Drug Synergism; Female; Fenoldopam; Glomerular Filtration Rate; Hyperemia; Proline; Renal Circulation; Serine; Sodium | 1993 |
Mechanism of the enhanced intrinsic activity of single-chain urokinase-type plasminogen activator during ongoing fibrinolysis.
Topics: Alanine; Binding Sites; Catalysis; Cell Line; Enzyme Activation; Fibrin; Fibrinolysis; Glutamates; Glutamic Acid; Humans; Kinetics; Lysine; Mutagenesis, Site-Directed; Plasminogen; Plasminogen Activator Inhibitor 1; Recombinant Proteins; Serine; Solutions; Urokinase-Type Plasminogen Activator | 1993 |
Functional expression of rat alpha 1 Na,K-ATPase containing substitutions for cysteines 454, 458, 459, 513 and 551.
Topics: Adenosine Triphosphate; Alanine; Animals; Blotting, Western; Cysteine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Mutagenesis, Site-Directed; Mutation; Ouabain; Rats; Serine; Sodium-Potassium-Exchanging ATPase; Transfection | 1993 |
Flash-induced electrogenic reactions in the SA(L223) reaction center mutant in Rhodobacter sphaeroides chromatophores.
Topics: Alanine; Bacterial Chromatophores; Base Sequence; DNA, Bacterial; Electron Transport; Hydrogen-Ion Concentration; Molecular Sequence Data; Mutagenesis, Site-Directed; Photochemistry; Photosynthetic Reaction Center Complex Proteins; Polyenes; Rhodobacter sphaeroides; Serine | 1994 |
Selection of beta-lactamase on filamentous bacteriophage by catalytic activity.
Topics: Alanine; Amino Acid Sequence; Base Sequence; beta-Lactamases; Binding Sites; Biotin; Catalysis; DNA Primers; Factor X; Genes, Viral; Indicators and Reagents; Inovirus; Kinetics; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Serine | 1994 |
K-ras-2 topographic genotyping of pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Alanine; Arginine; Aspartic Acid; Codon; Cysteine; DNA, Neoplasm; Exons; Forecasting; Genes, ras; Genotype; Glycine; Humans; Leucine; Mutation; Pancreas; Pancreatic Neoplasms; Serine; Survival Rate; Valine | 1994 |
Serine/alanine amino acid polymorphism of the L-cone photopigment assessed by dual Rayleigh-type color matches.
Topics: Adult; Alanine; Color Perception; Humans; Male; Ophthalmology; Photoreceptor Cells; Polymorphism, Genetic; Psychophysics; Retina; Rod Opsins; Serine | 1994 |
Regulation of Shaker K+ channel inactivation gating by the cAMP-dependent protein kinase.
Topics: Adenosine Triphosphate; Alanine; Alkaline Phosphatase; Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cyclic AMP-Dependent Protein Kinases; DNA Primers; Drosophila; Escherichia coli; Female; Genetic Variation; Ion Channel Gating; Kinetics; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Point Mutation; Polymerase Chain Reaction; Potassium Channels; Protein Structure, Secondary; Serine; Time Factors; Transcription, Genetic; Xenopus | 1994 |
Identification of serine-143 as the most likely precursor of dehydroalanine in the active site of histidine ammonia-lyase. A study of the overexpressed enzyme by site-directed mutagenesis.
Topics: Alanine; Base Sequence; Binding Sites; Chromatography, Gel; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine Ammonia-Lyase; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Pseudomonas putida; Recombinant Proteins; Serine | 1994 |
A study of the tryptophan synthase catalysed H/D exchange of the alpha-protons of amino acids.
Topics: Alanine; Glycine; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Protons; Serine; Substrate Specificity; Tryptophan Synthase | 1994 |
Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme.
Topics: Alanine; Amino Acid Sequence; Bacteriophage T4; Calorimetry; Circular Dichroism; Enzyme Stability; Models, Molecular; Muramidase; Mutagenesis, Site-Directed; Point Mutation; Protein Structure, Secondary; Recombinant Proteins; Serine; Threonine; Valine | 1993 |
Study of wild type and genetically modified reaction centers from Rhodobacter capsulatus: structural comparison with Rhodopseudomonas viridis and Rhodobacter sphaeroides.
Topics: Alanine; Amino Acid Sequence; Benzoquinones; Isoleucine; Kinetics; Light-Harvesting Protein Complexes; Mathematics; Mutagenesis, Site-Directed; Phenanthrolines; Photosynthetic Reaction Center Complex Proteins; Rhodobacter capsulatus; Rhodobacter sphaeroides; Rhodopseudomonas; Serine; Threonine | 1993 |
Serine-173 of the Epstein-Barr virus ZEBRA protein is required for DNA binding and is a target for casein kinase II phosphorylation.
Topics: Alanine; Amino Acid Sequence; B-Lymphocytes; Base Sequence; Binding Sites; Casein Kinase II; Cloning, Molecular; DNA Primers; DNA-Binding Proteins; Escherichia coli; Herpesvirus 4, Human; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Serine; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Viral Proteins | 1993 |
Possible role of both the alpha and beta gamma subunits of the heterotrimeric G protein, Gs, in transcytosis of the polymeric immunoglobulin receptor.
Topics: Alanine; Amino Acid Sequence; Animals; Cell Line; Cytosol; Dogs; Endocytosis; Epithelium; GTP-Binding Proteins; Immunoglobulin A; Immunoglobulin Fab Fragments; Kidney; Liver; Macromolecular Substances; Mutagenesis, Site-Directed; Organelles; Phosphorylation; Point Mutation; Rats; Receptors, Fc; Recombinant Proteins; Serine | 1993 |
The transport and metabolism of alanine by Giardia intestinalis.
Topics: Alanine; Animals; Biological Transport; Giardia lamblia; Serine; Temperature | 1993 |
Serine/alanine amino acid polymorphism of the L and M cone pigments: effects on Rayleigh matches among deuteranopes, protanopes and color normal observers.
Topics: Adult; Aged; Alanine; Amino Acid Sequence; Base Sequence; Color Perception; Color Vision Defects; DNA; Humans; Male; Middle Aged; Molecular Sequence Data; Polymorphism, Genetic; Retinal Pigments; Serine | 1993 |
Tests of the ability of two-cell mouse embryos to utilize selected precursors of phosphoenolpyruvic acid and pyruvic acid.
Topics: Alanine; Animals; Culture Media; Culture Techniques; Embryo, Mammalian; Embryonic and Fetal Development; Energy Metabolism; Female; Glyceric Acids; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Phosphoenolpyruvate; Pyruvates; Pyruvic Acid; Serine | 1993 |
Analysis of a mutant amino acid-activating domain of surfactin synthetase bearing a serine-to-alanine substitution at the site of carboxylthioester formation.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Base Sequence; DNA; Lipopeptides; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Peptide Synthases; Peptides, Cyclic; Restriction Mapping; Serine | 1993 |
Mutations of the alpha 2A-adrenergic receptor that eliminate detectable palmitoylation do not perturb receptor-G-protein coupling.
Topics: Acylation; Alanine; Allosteric Regulation; Amino Acid Sequence; Animals; Cell Line; Chromatography, Affinity; Cysteine; Dogs; Electrophoresis, Polyacrylamide Gel; Genetic Vectors; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Kidney; Kinetics; Mutagenesis, Site-Directed; Palmitic Acid; Palmitic Acids; Receptors, Adrenergic, beta; Recombinant Proteins; Serine; Swine; Transfection; Yohimbine | 1993 |
A point mutation in a Drosophila GABA receptor confers insecticide resistance.
Topics: Alanine; Amino Acid Sequence; Animals; Chloride Channels; Dieldrin; DNA Mutational Analysis; Drosophila melanogaster; Electrophysiology; Humans; Insecticide Resistance; Membrane Proteins; Muscimol; Oocytes; Picrotoxin; Point Mutation; Receptors, GABA-A; Serine; Sesterterpenes; Xenopus | 1993 |
Autoproteolysis of herpes simplex virus type 1 protease releases an active catalytic domain found in intermediate capsid particles.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Blotting, Western; Capsid; Centrifugation, Density Gradient; Chromatography, Affinity; Cloning, Molecular; Endopeptidases; Escherichia coli; Genes, Viral; Mutagenesis, Site-Directed; Plasmids; Point Mutation; Polymerase Chain Reaction; Recombinant Fusion Proteins; Restriction Mapping; Serine; Simplexvirus; Thrombin; Viral Proteins | 1993 |
Mutagenesis of ribosomal protein S8 from Escherichia coli: expression, stability, and RNA-binding properties of S8 mutants.
Topics: Alanine; Bacteriophage T7; Circular Dichroism; Escherichia coli; Genetic Vectors; Isoleucine; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Protein Conformation; Recombinant Proteins; Ribosomal Proteins; Serine | 1993 |
Multi-site phosphorylation of the protein tyrosine phosphatase, PTP1B: identification of cell cycle regulated and phorbol ester stimulated sites of phosphorylation.
Topics: Alanine; Amino Acid Sequence; CDC2 Protein Kinase; Cell Cycle; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Molecular Sequence Data; Mutation; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Serine; Tetradecanoylphorbol Acetate | 1993 |
Expression of a phosphorylation-resistant eukaryotic initiation factor 2 alpha-subunit mitigates heat shock inhibition of protein synthesis.
Topics: Alanine; Amino Acid Sequence; Animals; CHO Cells; Cloning, Molecular; Cricetinae; Eukaryotic Initiation Factor-2; Gene Expression; Hot Temperature; Macromolecular Substances; Mutagenesis, Site-Directed; Phosphorylation; Protein Biosynthesis; Recombinant Proteins; Serine; Transfection | 1993 |
Investigation of the role of conserved serine residues in the long form of the rat D2 dopamine receptor using site-directed mutagenesis.
Topics: Alanine; Allosteric Regulation; Animals; Cell Line, Transformed; Chlorocebus aethiops; Dopamine Agonists; Dopamine Antagonists; GTP-Binding Proteins; Guanosine Triphosphate; Hydrogen Bonding; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, Dopamine D2; Serine; Spiperone; Structure-Activity Relationship; Transfection | 1996 |
Hierarchal constitutive phosphorylation of the vesicular stomatitis virus P protein and lack of effect on P1 to P2 conversion.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Cell Line; DNA-Directed RNA Polymerases; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Phosphates; Phosphoproteins; Phosphorylation; RNA-Dependent RNA Polymerase; Serine; Threonine; Transfection; Vesicular stomatitis Indiana virus; Vesiculovirus; Viral Proteins; Viral Structural Proteins | 1995 |
Phosphorylation of the cytosolic domain of peptidylglycine alpha-amidating monooxygenase.
Topics: Alanine; Amino Acid Sequence; Animals; Antigen-Antibody Complex; Cell Line; Cell Membrane; Cytosol; Humans; Kidney; Kinetics; Mixed Function Oxygenases; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Point Mutation; Recombinant Proteins; Serine; Transfection | 1995 |
Reconstitution of skinned cardiac fibres with human recombinant cardiac troponin-I mutants and troponin-C.
Topics: Alanine; Animals; Base Sequence; Binding Sites; Calcium; Electrochemistry; Humans; In Vitro Techniques; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; Psoas Muscles; Recombinant Fusion Proteins; Serine; Structure-Activity Relationship; Swine; Troponin; Troponin C; Troponin I | 1995 |
Site-directed mutagenesis of Thermus thermophilus EF-Tu: the substitution of threonine-62 by serine or alanine.
Topics: Alanine; Base Sequence; Binding Sites; DNA Primers; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; RNA, Transfer, Amino Acyl; Serine; Thermus thermophilus; Threonine | 1995 |
Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in intact cells.
Topics: Alanine; Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Cricetinae; Fluorescent Antibody Technique, Indirect; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Immunoblotting; Molecular Sequence Data; Mutation; Phosphorylation; Serine; tau Proteins; Transfection | 1995 |
Amino-acid-type-selective triple-resonance experiments.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Calcium-Binding Proteins; Carbon; Carrier Proteins; Cysteine; Glycine; Image Enhancement; Isoleucine; Magnetic Resonance Spectroscopy; Methionine; Microfilament Proteins; Nitrogen; Serine; Valine | 1996 |
Characterization of phosphorylation-defective mutants of human P-glycoprotein expressed in mammalian cells.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Animals; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Cell Membrane; DNA Mutational Analysis; Drug Resistance, Multiple; Gene Expression; Humans; Mammals; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphorylation; Point Mutation; Recombinant Proteins; Restriction Mapping; Serine; Transfection; Vincristine | 1996 |
Phosphorylation of brain sodium channels in the I--II linker modulates channel function in Xenopus oocytes.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cyclic AMP-Dependent Protein Kinases; Electric Conductivity; Electrophysiology; Female; Ion Channel Gating; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Phosphorylation; Rats; Serine; Sodium Channels; Xenopus | 1996 |
Topological mapping of the cysteine residues of N-carbamyl-D-amino-acid amidohydrolase and their role in enzymatic activity.
Topics: Alanine; Amidohydrolases; Amino Acid Sequence; Base Sequence; Chromatography, High Pressure Liquid; Cysteine; DNA Primers; Genes, Bacterial; Iodoacetates; Iodoacetic Acid; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Plasmids; Point Mutation; Recombinant Proteins; Restriction Mapping; Rhizobium; Serine | 1996 |
The activity of D-raf in torso signal transduction is altered by serine substitution, N-terminal deletion, and membrane targeting.
Topics: Alanine; Animals; Base Sequence; Drosophila melanogaster; Drosophila Proteins; Embryo, Nonmammalian; Gene Expression Regulation, Developmental; Humans; Membrane Proteins; Molecular Sequence Data; Morphogenesis; Mutagenesis, Site-Directed; Nucleopolyhedroviruses; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Receptor Protein-Tyrosine Kinases; Recombinant Proteins; Sequence Deletion; Serine; Signal Transduction; Spodoptera | 1996 |
Molecular characterization of the di-leucine-based internalization motif of the T cell receptor.
Topics: Alanine; Amino Acid Sequence; Cell Line; Cell Membrane; Down-Regulation; Humans; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phorbol 12,13-Dibutyrate; Phosphorylation; Point Mutation; Protein Kinase C; Receptor-CD3 Complex, Antigen, T-Cell; Recombinant Proteins; Serine; Substrate Specificity; Transfection | 1996 |
Rate-determining steps in the biosynthesis of glycogen in COS cells.
Topics: 1,4-alpha-Glucan Branching Enzyme; Alanine; Animals; Cell Line; Chlorocebus aethiops; Genetic Vectors; Glucosyltransferases; Glycogen; Glycogen Synthase; Glycoproteins; Kinetics; Muscle, Skeletal; Mutagenesis, Site-Directed; Point Mutation; Rabbits; Recombinant Proteins; Serine; Time Factors; Transfection; UTP-Glucose-1-Phosphate Uridylyltransferase | 1996 |
Site-directed mutagenesis of the conserved serine 138 of human placental NAD+-dependent 15-hydroxyprostaglandin dehydrogenase to an alanine results in an inactive enzyme.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Blotting, Western; Conserved Sequence; Escherichia coli; Female; Gene Expression; Humans; Hydroxyprostaglandin Dehydrogenases; Molecular Sequence Data; Mutagenesis, Site-Directed; Placenta; Serine; Structure-Activity Relationship | 1996 |
Actions of acidic fibroblast growth factor fragments on food intake in rats.
Topics: Alanine; Animals; Antibodies; Eating; Fibroblast Growth Factor 1; Hypothalamic Area, Lateral; Male; Peptide Fragments; Rats; Rats, Wistar; Receptors, Fibroblast Growth Factor; Serine; Structure-Activity Relationship | 1995 |
The Gly74-->Ser and Ser3-->Ala mutations in Rhodobacter sphaeroides Y thioredoxin: effects on active site reactivity and protein interaction.
Topics: Alanine; Amino Acid Sequence; Bacteriophage T7; Base Sequence; Binding Sites; DNA, Recombinant; Glycine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Disulfide Reductase (Glutathione); Rhodobacter sphaeroides; Serine; Thioredoxins; Viral Proteins | 1996 |
Is the NAD(P)H:flavin oxidoreductase from Escherichia coli a member of the ferredoxin-NADP+ reductase family?. Evidence for the catalytic role of serine 49 residue.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Catalysis; DNA Primers; Escherichia coli; Flavins; FMN Reductase; Hydroxyl Radical; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NADH, NADPH Oxidoreductases; NADP; Sequence Alignment; Serine; Threonine | 1996 |
Phosphorylation of a cAMP-specific phosphodiesterase (HSPDE4B2B) by mitogen-activated protein kinase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Alanine; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; Escherichia coli; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Peptide Fragments; Phosphopeptides; Phosphorylation; Point Mutation; Recombinant Proteins; Saccharomyces cerevisiae; Serine; Spodoptera; Substrate Specificity; Transfection | 1996 |
Residues near the amino and carboxyl termini of staphylococcal enterotoxin E independently mediate TCR V beta-specific interactions.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Asparagine; Enterotoxins; Epitopes; Histocompatibility Antigens Class II; Humans; Mice; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Protein Binding; Receptors, Antigen, T-Cell, alpha-beta; Serine; Staphylococcus aureus; Superantigens | 1996 |
Enhancement of recombinant alpha 1 beta 1 gamma 2L gamma-aminobutyric acidA receptor whole-cell currents by protein kinase C is mediated through phosphorylation of both beta 1 and gamma 2L subunits.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Cattle; Chloride Channels; DNA Primers; gamma-Aminobutyric Acid; Kinetics; L Cells; Macromolecular Substances; Membrane Potentials; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Phosphorylation; Point Mutation; Protein Kinase C; Protein Multimerization; Receptors, GABA-A; Recombinant Proteins; Serine; Transfection | 1996 |
Changes in the intracellular free amino acid pool in human saphenous vein tissue culture.
Topics: Aged; Alanine; Amino Acids; Asparagine; Aspartic Acid; Culture Techniques; Cytosol; Glutamic Acid; Glutamine; Glycine; Humans; Middle Aged; Proline; Saphenous Vein; Serine; Taurine | 1996 |
Hydrophilic side chains in the third and seventh transmembrane helical domains of human A2A adenosine receptors are required for ligand recognition.
Topics: Adenosine; Adenylyl Cyclases; Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Binding, Competitive; Cyclic AMP; GTP-Binding Proteins; Humans; Kinetics; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Point Mutation; Polymerase Chain Reaction; Protein Structure, Secondary; Radioligand Assay; Receptor, Adenosine A2A; Receptors, Purinergic P1; Recombinant Proteins; Ribose; Sequence Tagged Sites; Serine | 1996 |
Differential regulation of c-Myb-induced transcription activation by a phosphorylation site in the negative regulatory domain.
Topics: Alanine; Animals; Avian Myeloblastosis Virus; Binding Sites; Cell Line; Chlorocebus aethiops; DNA; Gene Expression Regulation; Mice; Molecular Weight; Phosphorylation; Proline; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Serine; Structure-Activity Relationship; Trans-Activators; Transcription, Genetic; Transcriptional Activation | 1996 |
Molecular determinants for activation and inactivation of HERG, a human inward rectifier potassium channel.
Topics: Alanine; Animals; Biotransformation; Humans; Ion Channel Gating; Kinetics; Membrane Potentials; Mutation; Oocytes; Patch-Clamp Techniques; Polymerase Chain Reaction; Potassium Channels; Sequence Deletion; Serine; Xenopus laevis | 1996 |
Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells.
Topics: Alanine; Amino Acid Sequence; Animals; Breast Neoplasms; Cell Division; Chemotaxis; Drosophila; Female; Glycine; Histidine; Humans; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Mutagenesis, Site-Directed; Neuroblastoma; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Phosphorylation; Polymerase Chain Reaction; Proline; Recombinant Proteins; Serine; Transcription Factors; Transfection; Tumor Cells, Cultured | 1996 |
The magnitude of the backbone conformational entropy change in protein folding.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Calorimetry, Differential Scanning; Computer Simulation; Egg White; Entropy; Leucine Zippers; Molecular Sequence Data; Muramidase; Mutation; Protein Conformation; Protein Folding; Serine; Solvents; Temperature | 1996 |
Negative regulation of Raf-1 by phosphorylation of serine 621.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Chlorocebus aethiops; Cloning, Molecular; Consensus Sequence; COS Cells; Cysteine; Homeostasis; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Peptide Mapping; Phosphorylation; Point Mutation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Recombinant Proteins; Serine; Transfection | 1996 |
Expression and characterization of glycogen synthase kinase-3 mutants and their effect on glycogen synthase activity in intact cells.
Topics: Alanine; Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cloning, Molecular; DNA Primers; Escherichia coli; Glutamic Acid; Glycogen Synthase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Kidney; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Rabbits; Recombinant Proteins; Serine; Transfection | 1996 |
Mutagenesis of ser41 to ala inhibits the association of GAP-43 with the membrane skeleton of GAP-43-deficient PC12B cells: effects on cell adhesion and the composition of neurite cytoskeleton and membrane.
Topics: Alanine; Animals; Calcium; Calmodulin; Cell Adhesion; Cell Membrane; Cells, Cultured; Cytoskeleton; GAP-43 Protein; Image Processing, Computer-Assisted; Immunohistochemistry; Integrins; Membrane Glycoproteins; Microscopy, Video; Mutagenesis; Nerve Tissue Proteins; Neurites; Neurofilament Proteins; PC12 Cells; Rats; Serine; Subcellular Fractions; Transfection | 1996 |
The metabotropic glutamate receptor antagonist L-2-amino-3-phosphonopropionic acid inhibits phosphoserine phosphatase.
Topics: Alanine; Animals; Cerebral Cortex; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kinetics; Phosphoric Monoester Hydrolases; Rats; Receptors, Metabotropic Glutamate; Serine; Stereoisomerism | 1996 |
Replacement of Ser657 of protein kinase C-alpha by alanine leads to premature down regulation after phorbol-ester-induced translocation to the membrane.
Topics: Alanine; Animals; Binding Sites; Biological Transport, Active; Cattle; Cell Membrane; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Isoenzymes; LLC-PK1 Cells; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Serine; Swine; Tetradecanoylphorbol Acetate | 1996 |
Formation of D-serine from L-phosphoserine in brain synaptosomes.
Topics: Alanine; Animals; Biological Transport; Cerebral Cortex; Excitatory Amino Acid Antagonists; Hydrolysis; Kinetics; Male; Phosphoric Monoester Hydrolases; Phosphoserine; Rats; Rats, Sprague-Dawley; Serine; Stereoisomerism; Synaptosomes | 1996 |
Serine 752 in the cytoplasmic domain of the beta 3 integrin subunit is not required for alpha v beta 3 postreceptor signaling events.
Topics: Alanine; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antigens, CD; Cell Adhesion; CHO Cells; Cricetinae; Cytoskeleton; Extracellular Matrix Proteins; Fibrinogen; Genetic Complementation Test; Humans; Integrin beta3; Molecular Sequence Data; Oligopeptides; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Point Mutation; Proline; Protein Binding; Receptors, Vitronectin; Recombinant Fusion Proteins; Sequence Alignment; Serine; Signal Transduction; Thrombasthenia; Transfection; Vitronectin; von Willebrand Factor | 1996 |
Characterization of herpes simplex virus type 1 recombinants with mutations in the cytoplasmic tail of glycoprotein H.
Topics: Alanine; Animals; Binding Sites; Cell Line; Chlorocebus aethiops; COS Cells; Herpesvirus 1, Human; Humans; Mutation; Point Mutation; Proline; Recombination, Genetic; Sequence Deletion; Serine; Structure-Activity Relationship; Valine; Vero Cells; Viral Envelope Proteins; Viral Plaque Assay | 1996 |
Regulation of type I adenylyl cyclase by calmodulin kinase IV in vivo.
Topics: Adenylyl Cyclases; Alanine; Animals; Binding Sites; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Membrane; Cyclic AMP; Humans; Kidney; Kinetics; Long-Term Potentiation; Memory; Mice; Mice, Neurologic Mutants; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Recombinant Proteins; Serine | 1996 |
Ser644 is important for catalytic activity but is not involved in cAMP-dependent phosphorylation of yeast 6-phosphofructo-2-kinase.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Cloning, Molecular; Cyclic AMP; Escherichia coli; Glucose; Kinetics; Mutagenesis, Site-Directed; Phosphofructokinase-2; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Point Mutation; Recombinant Proteins; Saccharomyces cerevisiae; Serine | 1996 |
Conformational study based on simulated annealing and 1H NMR of peptides comprising the consensus sequence Arg5-Asp-Val-Arg-Gly9: effects of the substitution Ser 12 by Ala 12 or of 3 residues deletion at the N-terminus.
Topics: Alanine; Amino Acid Sequence; Animals; Computer Simulation; Consensus Sequence; Magnetic Resonance Spectroscopy; Metalloendopeptidases; Molecular Sequence Data; Oligopeptides; Protein Conformation; Serine; Structure-Activity Relationship; Xenopus laevis | 1996 |
Constitutively active human estrogen receptors containing amino acid substitutions for tyrosine 537 in the receptor protein.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Breast Neoplasms; CHO Cells; Cricetinae; Estradiol; Histone Acetyltransferases; Humans; Molecular Sequence Data; Mutation; Nuclear Receptor Coactivator 1; Phenotype; Phosphorylation; Receptors, Estrogen; Recombinant Proteins; Serine; Structure-Activity Relationship; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Tyrosine | 1996 |
Modified ligands to FA and FB in photosystem I. Proposed chemical rescue of a [4Fe-4S] cluster with an external thiolate in alanine, glycine, and serine mutants of PsaC.
Topics: Alanine; Bacterial Proteins; Cytochromes; Cytochromes f; Electron Spin Resonance Spectroscopy; Electron Transport; Glycine; Iron-Sulfur Proteins; Kinetics; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Photosynthetic Reaction Center Complex Proteins; Photosystem I Protein Complex; Serine; Structure-Activity Relationship | 1996 |
Molecular mimicry in development: identification of ste11+ as a substrate and mei3+ as a pseudosubstrate inhibitor of ran1+ kinase.
Topics: Alanine; Arginine; Aspartic Acid; Calcium-Calmodulin-Dependent Protein Kinases; DNA Mutational Analysis; Enzyme Inhibitors; Fungal Proteins; GTP Phosphohydrolases; GTP-Binding Proteins; Meiosis; Mutagenesis, Site-Directed; Nuclear Proteins; Phosphorylation; ran GTP-Binding Protein; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Sequence Homology, Amino Acid; Serine; Substrate Specificity; Transcription Factors | 1996 |
Identification of an active site cysteine residue in human type I Ins(1,4,5)P3 5-phosphatase by chemical modification and site-directed mutagenesis.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Cattle; Circular Dichroism; Cysteine; Enzyme Inhibitors; Humans; Indicators and Reagents; Inositol Polyphosphate 5-Phosphatases; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoric Monoester Hydrolases; Sequence Alignment; Serine; Substrate Specificity; Sulfhydryl Compounds | 1996 |
Structure-function relationships among wild-type variants of Staphylococcus aureus beta-lactamase: importance of amino acids 128 and 216.
Topics: Alanine; Asparagine; beta-Lactamases; Crystallography, X-Ray; Gene Expression; Genetic Variation; Kinetics; Serine; Staphylococcus aureus; Structure-Activity Relationship; Threonine | 1996 |
Mechanisms of amino acid-induced insulin secretion from the glucose-responsive BRIN-BD11 pancreatic B-cell line.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Calcium Channel Blockers; Cell Line; Diazoxide; Dose-Response Relationship, Drug; Glucose; Glutamine; Glyceraldehyde; Glycine; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Lysine; Potassium Channels; Proline; Radioimmunoassay; Rats; Serine; Stimulation, Chemical; Verapamil | 1996 |
Nonenzymatic anticoagulant activity of the mutant serine protease Ser360Ala-activated protein C mediated by factor Va.
Topics: Alanine; Anticoagulants; Cell Line; Factor Va; Humans; Mutagenesis; Protein C; Serine | 1997 |
Neurochemical changes in cerebellum of goldfish exposed to various temperatures.
Topics: Acclimatization; Adenine Nucleotides; Adenosine; Alanine; Animals; Aspartic Acid; Cerebellum; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Goldfish; Kinetics; Potassium; Serine; Taurine; Temperature | 1997 |
The conformational change responsible for AT1 receptor activation is dependent upon two juxtaposed asparagine residues on transmembrane helices III and VII.
Topics: Alanine; Amino Acid Sequence; Angiotensin I; Animals; Asparagine; Cell Line; Humans; Inositol 1,4,5-Trisphosphate; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Rats; Receptors, Angiotensin; Sequence Homology, Amino Acid; Serine; Transfection | 1997 |
Modulation of bovine papillomavirus DNA replication by phosphorylation of the viral E1 protein.
Topics: Adenosine Triphosphatases; Alanine; Animals; Binding Sites; Bovine papillomavirus 1; Cattle; Cell Line; CHO Cells; Cricetinae; DNA Helicases; DNA Replication; DNA-Binding Proteins; DNA, Viral; Genome, Viral; Glutamic Acid; Mice; Mutagenesis; Phosphorylation; Recombinant Fusion Proteins; Replication Origin; Serine; Spodoptera; Tumor Cells, Cultured; Viral Proteins; Virus Replication | 1997 |
Molecular structure of the sarcomeric M band: mapping of titin and myosin binding domains in myomesin and the identification of a potential regulatory phosphorylation site in myomesin.
Topics: Alanine; Animals; Bacteriophage lambda; Binding Sites; Cattle; Connectin; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Humans; Membrane Proteins; Muscle Proteins; Muscle, Skeletal; Mutagenesis, Site-Directed; Myosins; Phosphorylation; Polymerase Chain Reaction; Protein Kinases; Rabbits; Recombinant Proteins; Sarcomeres; Serine | 1997 |
Autophosphorylation-inactivation site of hexokinase 2 in Saccharomyces cerevisiae.
Topics: Alanine; Cysteine; Hexokinase; Phosphorylation; Point Mutation; Saccharomyces cerevisiae; Serine | 1997 |
Serine319 and 321 are functional in isocitrate lyase from Escherichia coli.
Topics: Alanine; Asparagine; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression Regulation, Bacterial; Glycine; Histidine; Isocitrate Lyase; Isocitrates; Kinetics; Magnesium; Mutagenesis, Site-Directed; Oligonucleotides; Plasmids; Proline; Sequence Alignment; Serine; Threonine | 1997 |
Alteration of a single serine in the basic domain of the Epstein-Barr virus ZEBRA protein separates its functions of transcriptional activation and disruption of latency.
Topics: Alanine; B-Lymphocytes; Binding Sites; Cell Line; DNA; DNA-Binding Proteins; Gene Expression; Genes, Reporter; Herpesvirus 4, Human; Humans; Point Mutation; Promoter Regions, Genetic; Recombinant Fusion Proteins; Serine; Trans-Activators; Transcriptional Activation; Tumor Cells, Cultured; Viral Proteins; Virus Latency | 1997 |
Differential phosphorylation of chicken progesterone receptor in hormone-dependent and ligand-independent activation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alanine; Animals; Benzazepines; Cell Line; Chickens; Chloramphenicol O-Acetyltransferase; Dopamine Agonists; Genes, Reporter; Humans; Kinetics; Ligands; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Progesterone; Receptors, Progesterone; Recombinant Proteins; Serine; Transfection | 1997 |
Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinase.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cloning, Molecular; DNA Primers; DNA-Binding Proteins; Epidermal Growth Factor; Genes, Reporter; Humans; Mice; Microbodies; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Point Mutation; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Transcription Factors; Transcription, Genetic; Transfection | 1997 |
Target-dependent effect of phosphorylation on the DNA binding activity of the TAL1/SCL oncoprotein.
Topics: Alanine; Animals; Basic Helix-Loop-Helix Transcription Factors; Binding Sites; Cyclic AMP-Dependent Protein Kinases; DNA; DNA-Binding Proteins; Mice; Mutagenesis; Neoplasm Proteins; Phosphopeptides; Phosphoproteins; Phosphorylation; Protein Binding; Proto-Oncogene Proteins; Sequence Homology, Amino Acid; Serine; T-Cell Acute Lymphocytic Leukemia Protein 1; Transcription Factors | 1997 |
Bcl-2 phosphorylation required for anti-apoptosis function.
Topics: Alanine; Animals; Apoptosis; Bryostatins; Cell Line; Dimerization; Enzyme Activation; Etoposide; Glutamic Acid; Interleukin-3; Kinetics; Lactones; Macrolides; Mice; Mutagenesis, Site-Directed; Phosphates; Phosphorylation; Point Mutation; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Serine; Transfection | 1997 |
Partition of transient and sustained inhibitory glycinergic input to retinal ganglion cells.
Topics: Alanine; Ambystoma; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Glycine Agents; Kynurenic Acid; Receptors, Glycine; Retinal Ganglion Cells; Serine; Strychnine; Synaptic Transmission; Taurine | 1997 |
A prevalent amino acid polymorphism at codon 98 in the hepatocyte nuclear factor-1alpha gene is associated with reduced serum C-peptide and insulin responses to an oral glucose challenge.
Topics: Administration, Oral; Adult; Aged; Alanine; Amino Acids; Asparagine; C-Peptide; Codon; DNA-Binding Proteins; Female; Glucose; Glucose Tolerance Test; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Insulin; Insulin Secretion; Isoleucine; Leucine; Male; Middle Aged; Nuclear Proteins; Polymorphism, Genetic; Serine; Transcription Factors; Valine | 1997 |
High-affinity binding of bioactive glycosylation-inhibiting factor to antigen-primed T cells and natural killer cells.
Topics: Alanine; Animals; Asparagine; Binding Sites; Cell Line; Cysteine; Escherichia coli; Humans; Hybridomas; Killer Cells, Natural; Kinetics; Lymphocyte Activation; Lymphokines; Macrophages; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed; Point Mutation; Prostatic Secretory Proteins; Recombinant Proteins; Serine; Suppressor Factors, Immunologic; T-Lymphocytes, Regulatory; Tumor Necrosis Factor-alpha | 1997 |
The carboxyl-terminal region of STAT3 controls gene induction by the mouse haptoglobin promoter.
Topics: Alanine; Animals; Antigens, CD; Base Sequence; Binding Sites; COS Cells; Dexamethasone; DNA-Binding Proteins; Haptoglobins; Humans; Interleukin-6; Kinetics; Mice; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Promoter Regions, Genetic; Receptors, Interleukin; Receptors, Interleukin-3; Receptors, Interleukin-6; Recombinant Fusion Proteins; Sequence Deletion; Serine; Signal Transduction; STAT3 Transcription Factor; Trans-Activators; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1997 |
Rhodopsin phosphorylation sites and their role in arrestin binding.
Topics: Alanine; Amino Acid Sequence; Animals; Arrestin; Binding Sites; Cattle; Cell Line; Eye Proteins; G-Protein-Coupled Receptor Kinase 1; Humans; Kinetics; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Protein Kinases; Protein Structure, Secondary; Recombinant Proteins; Rhodopsin; Serine; Threonine; Transfection | 1997 |
Phosphorylation of serine 256 is required for cAMP-dependent regulatory exocytosis of the aquaporin-2 water channel.
Topics: Alanine; Animals; Aquaporin 2; Aquaporin 6; Aquaporins; Cell Line; Cyclic AMP; Exocytosis; Ion Channels; Light; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Rats; Recombinant Proteins; Scattering, Radiation; Serine; Thionucleotides; Transfection | 1997 |
Mutational analysis of 26 residues of vaccinia DNA topoisomerase identifies Ser-204 as important for DNA binding and cleavage.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; DNA Mutational Analysis; DNA Topoisomerases, Type I; DNA, Superhelical; DNA, Viral; Magnesium; Molecular Sequence Data; Mutagenesis, Site-Directed; Serine; Sodium Chloride; Vaccinia virus; Viral Proteins | 1997 |
Role of the glycine triad in the ATP-binding site of cAMP-dependent protein kinase.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Animals; Binding Sites; Cyclic AMP-Dependent Protein Kinases; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Glycine; Kinetics; Mice; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Serine; Stereoisomerism; Temperature | 1997 |
6-L-alanineferrirubin, a ferrichrome-type siderophore from the fungus Aspergillus ochraceous.
Topics: Alanine; Aspergillus ochraceus; Crystallography, X-Ray; Ferric Compounds; Glycine; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Molecular Structure; Peptides, Cyclic; Serine; Siderophores | 1997 |
Mitosis-specific phosphorylation of gar2, a fission yeast nucleolar protein structurally related to nucleolin.
Topics: Alanine; Animals; Binding Sites; Casein Kinase II; CDC2 Protein Kinase; Cell Cycle; Cell Nucleolus; CHO Cells; Cricetinae; Cyclin-Dependent Kinases; Female; Fungal Proteins; Mitosis; Mutation; Nuclear Proteins; Nucleolin; Oocytes; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Recombinant Proteins; RNA-Binding Proteins; RNA, Ribosomal, 18S; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Serine; Starfish; Temperature | 1997 |
Phosphorylation at conserved carboxyl-terminal hydrophobic motif regulates the catalytic and regulatory domains of protein kinase C.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Calcium; Cell Line; Conserved Sequence; DNA Primers; Enzyme Stability; Glutamic Acid; Glycerol; Kinetics; Liposomes; Models, Structural; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Polymerase Chain Reaction; Protein Conformation; Protein Kinase C; Protein Kinase C beta; Recombinant Proteins; Serine; Spodoptera; Thermodynamics; Transfection | 1997 |
CFTR activation: additive effects of stimulatory and inhibitory phosphorylation sites in the R domain.
Topics: 1-Methyl-3-isobutylxanthine; Alanine; Animals; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Female; Kinetics; Membrane Potentials; Mutagenesis, Site-Directed; Oocytes; Phosphorylation; Point Mutation; Recombinant Proteins; Serine; Xenopus laevis | 1997 |
Molecular structures of the S124A, S124T, and S124V site-directed mutants of UDP-galactose 4-epimerase from Escherichia coli.
Topics: Alanine; Binding Sites; Crystallography, X-Ray; Escherichia coli; Glucose; Macromolecular Substances; Mutagenesis, Site-Directed; NAD; Serine; Substrate Specificity; Threonine; UDPglucose 4-Epimerase; Uridine Diphosphate; Valine | 1997 |
Extensible collagen in mussel byssus: a natural block copolymer.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Biopolymers; Bivalvia; Collagen; DNA, Complementary; Elasticity; Elastin; Fibroins; Glycine; Histidine; Molecular Sequence Data; Proline; Protein Conformation; Protein Precursors; Protein Structure, Secondary; Sequence Alignment; Serine | 1997 |
The involvement of serine 175 and alanine 185 of cytochrome b of Rhodobacter sphaeroides cytochrome bc1 complex in interaction with iron-sulfur protein.
Topics: Alanine; Electron Spin Resonance Spectroscopy; Electron Transport Complex III; Ethylmaleimide; Iron-Sulfur Proteins; Mutagenesis, Site-Directed; Photosynthesis; Protein Binding; Rhodobacter sphaeroides; Serine | 1997 |
Mutation of cysteine 111 in Dopa decarboxylase leads to active site perturbation.
Topics: 5-Hydroxytryptophan; Alanine; Animals; Base Sequence; Binding Sites; Circular Dichroism; Cysteine; Dopa Decarboxylase; Hydrogen-Ion Concentration; Kidney; Kinetics; Levodopa; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Serine; Spectrometry, Fluorescence; Spectrophotometry; Structure-Activity Relationship; Swine | 1997 |
Mutations in the C-terminal domain of Sonic Hedgehog cause holoprosencephaly.
Topics: Alanine; Amino Acid Sequence; Animals; Cell Line, Transformed; DNA Mutational Analysis; Exons; Female; Genes, Dominant; Glutamic Acid; Glycine; Hedgehog Proteins; Holoprosencephaly; Humans; Male; Molecular Sequence Data; Pedigree; Point Mutation; Proteins; Sequence Deletion; Sequence Homology, Amino Acid; Serine; Threonine; Trans-Activators; Valine | 1997 |
A conserved cysteine residue in yeast uroporphyrinogen decarboxylase is not essential for enzymatic activity.
Topics: Alanine; Cysteine; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Mutagenesis, Site-Directed; Plasmids; Saccharomyces cerevisiae; Serine; Transformation, Genetic; Uroporphyrinogen Decarboxylase | 1997 |
Characterization and expression of two chicken cDNAs encoding ubiquitin fused to ribosomal proteins of 52 and 80 amino acids.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Base Sequence; Chick Embryo; Chickens; Cloning, Molecular; Gene Expression; Genome; Humans; Male; Molecular Sequence Data; Molecular Structure; Phylogeny; Polymerase Chain Reaction; Protein Biosynthesis; Pyrimidines; Rats; Ribonucleases; Ribosomal Proteins; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serine; Spermatogenesis; Ubiquitins | 1997 |
Ser165 of transmembrane helix IV is not involved in the interaction of catecholamines with the alpha-2a-adrenoceptor.
Topics: Alanine; Animals; Catecholamines; COS Cells; Dopamine; Epinephrine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Norepinephrine; Radioligand Assay; Receptors, Adrenergic, alpha-2; Serine | 1997 |
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.
Topics: Alanine; Amino Acid Sequence; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Binding Sites; Cell Line; Electrophysiology; Enflurane; Ethanol; Glycine; Humans; Molecular Sequence Data; Mutagenesis; Propofol; Receptors, GABA-A; Receptors, Glycine; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Tryptophan; Xenopus | 1997 |
Agonist-induced desensitization of the mu opioid receptor is determined by threonine 394 preceded by acidic amino acids in the COOH-terminal tail.
Topics: Alanine; Amino Acid Sequence; Animals; Binding, Competitive; CHO Cells; Cricetinae; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Point Mutation; Rats; Receptors, Opioid, mu; Recombinant Proteins; Serine; Threonine; Transfection | 1997 |
Evidence that Ser775 in the alpha subunit of the Na,K-ATPase is a residue in the cation binding pocket.
Topics: Adenosine Triphosphate; Alanine; Animals; Binding Sites; Cations, Monovalent; Enzyme Inhibitors; HeLa Cells; Humans; Isothiuronium; Kinetics; Macromolecular Substances; Mutagenesis, Site-Directed; Ouabain; Point Mutation; Potassium; Recombinant Proteins; Rubidium; Serine; Sheep; Sodium-Potassium-Exchanging ATPase; Time Factors; Transfection | 1997 |
Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3.
Topics: Alanine; Alzheimer Disease; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Embryonal; Cell Differentiation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Kinetics; Lithium Chloride; Microtubules; Mutagenesis, Site-Directed; Neurons; Phosphorylation; Point Mutation; Recombinant Proteins; Sequence Tagged Sites; Serine; tau Proteins; Transfection; Tretinoin; Tumor Cells, Cultured | 1997 |
PKA-mediated phosphorylation and inhibition of Na(+)-K(+)-ATPase in response to beta-adrenergic hormone.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Alanine; Animals; Cell Line; Colforsin; COS Cells; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoproterenol; Isoquinolines; Macromolecular Substances; Mutagenesis, Site-Directed; Okadaic Acid; Phosphorylation; Point Mutation; Rats; Recombinant Proteins; Rubidium; Serine; Sodium-Potassium-Exchanging ATPase; Spodoptera; Sulfonamides; Transfection | 1997 |
Site-directed mutagenesis of the Actinomadura R39 DD-peptidase.
Topics: Actinomycetales; Alanine; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Carboxypeptidases; Carrier Proteins; Conserved Sequence; Glycine; Hexosyltransferases; Kinetics; Molecular Sequence Data; Muramoylpentapeptide Carboxypeptidase; Mutagenesis, Site-Directed; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases; Protein Denaturation; Protein Structure, Secondary; Recombinant Proteins; Serine; Serine-Type D-Ala-D-Ala Carboxypeptidase; Substrate Specificity | 1997 |
Site-directed mutagenesis of the Cys residues in ClpA, the ATPase component of protease Ti (ClpAP) in Escherichia coli.
Topics: Adenosine Triphosphatases; Alanine; Caseins; Cysteine; Electrophoresis, Polyacrylamide Gel; Endopeptidase Clp; Escherichia coli; Escherichia coli Proteins; Ethylmaleimide; Mutagenesis, Site-Directed; Serine; Serine Endopeptidases; Sulfhydryl Reagents | 1997 |
Further evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Alanine; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Insulin; Insulin-Like Growth Factor I; Isoenzymes; Mutagenesis, Site-Directed; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Transfection; Tyrosine | 1997 |
Intersubunit communication in hybrid hexamers of K89L/A163G/S380A and C320S mutants of glutamate dehydrogenase from Clostridium symbiosum.
Topics: Alanine; Allosteric Regulation; Clostridium; Dithionitrobenzoic Acid; Glutamate Dehydrogenase; Glutamic Acid; Lysine; NAD; Protein Conformation; Protein Denaturation; Protein Folding; Recombinant Proteins; Serine | 1997 |
The rat serotonin transporter: identification of cysteine residues important for substrate transport.
Topics: Alanine; Amino Acid Substitution; Animals; Carrier Proteins; Cell Line; Cell Membrane; Citalopram; Cysteine; Humans; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Conformation; Rats; Recombinant Proteins; Serine; Serotonin; Serotonin Plasma Membrane Transport Proteins; Transfection | 1997 |
Serine-294 and threonine-295 in the exofacial loop domain between helices 7 and 8 of glucose transporters (GLUT) are involved in the conformational alterations during the transport process.
Topics: Alanine; Amino Acid Sequence; Animals; Biological Transport; COS Cells; Glucose Transporter Type 4; Glycine; Molecular Sequence Data; Monosaccharide Transport Proteins; Muscle Proteins; Mutagenesis, Site-Directed; Protein Conformation; Sequence Homology, Amino Acid; Serine; Threonine | 1998 |
A search for endogenous amino acids in martian meteorite ALH84001.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Glycine; Mars; Meteoroids; Serine; Stereoisomerism | 1998 |
Regulation of rat Na(+)-K(+)-ATPase activity by PKC is modulated by state of phosphorylation of Ser-943 by PKA.
Topics: Alanine; Amino Acid Substitution; Animals; Colforsin; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Dichlororibofuranosylbenzimidazole; Enzyme Activation; Homeostasis; Isoenzymes; Kinetics; Mutagenesis, Site-Directed; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Rats; Recombinant Proteins; Serine; Sodium-Potassium-Exchanging ATPase; Thionucleotides; Transfection | 1997 |
Esterification of 9-fluorenylmethoxycarbonyl-glycosylated serine and cysteine derivatives with an hydroxymethyl resin.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Chromatography, High Pressure Liquid; Cysteine; Dinitrobenzenes; Esterification; Fluorenes; Glycosylation; Indicators and Reagents; Magnetic Resonance Spectroscopy; Peptides; Resins, Plant; Serine; Stereoisomerism; Triazines | 1997 |
The role of the seventh transmembrane region in high affinity binding of a beta 2-selective agonist TA-2005.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Alanine; Amphetamines; Animals; Binding Sites; Cell Membrane; COS Cells; Hydroxyquinolines; Isoproterenol; Kinetics; Mutagenesis, Site-Directed; Quinolones; Receptors, Adrenergic, beta-2; Recombinant Fusion Proteins; Serine; Substrate Specificity | 1998 |
Autocatalytic removal of the pro-sequence from kexins requires an intact P-domain.
Topics: Alanine; Amino Acid Substitution; Animals; Binding Sites; Catalysis; Cell-Free System; Female; Mutagenesis, Site-Directed; Oocytes; Proprotein Convertases; Protein Biosynthesis; Protein Processing, Post-Translational; Recombinant Proteins; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Serine; Subtilisins; Xenopus | 1997 |
Role of the NH2 terminus of the cloned renal K+ channel, ROMK1, in arachidonic acid-mediated inhibition.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arachidonic Acid; Cell Line; Cloning, Molecular; Female; Ion Channel Gating; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Rats; Recombinant Proteins; Sequence Alignment; Serine; Transfection; Xenopus laevis | 1998 |
Cysteine 195 has a critical functional role in catalysis by isocitrate lyase from Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cysteine; Escherichia coli; Glycine; Isocitrate Lyase; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Sequence Alignment; Sequence Analysis; Sequence Homology, Amino Acid; Serine; Threonine; Valine | 1997 |
Arylsulfatase from Klebsiella pneumoniae carries a formylglycine generated from a serine.
Topics: Alanine; Amino Acid Sequence; Arylsulfatases; Glycine; Klebsiella pneumoniae; Molecular Sequence Data; Peptide Fragments; Prokaryotic Cells; Protein Processing, Post-Translational; Serine | 1998 |
A method for the identification of promoters recognized by RNA polymerase containing a particular sigma factor: cloning of a developmentally regulated promoter and corresponding gene directed by the Streptomyces aureofaciens sigma factor RpoZ.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA-Binding Proteins; DNA-Directed RNA Polymerases; Isoelectric Point; Molecular Sequence Data; Open Reading Frames; Promoter Regions, Genetic; Serine; Sigma Factor; Spores, Bacterial; Streptomyces aureofaciens; Threonine; Transcription, Genetic | 1998 |
Substrate inhibition of D-amino acid transaminase and protection by salts and by reduced nicotinamide adenine dinucleotide: isolation and initial characterization of a pyridoxo intermediate related to inactivation.
Topics: Alanine; Catalysis; Chromatography, High Pressure Liquid; D-Alanine Transaminase; Enzyme Inhibitors; NAD; Pyridoxal Phosphate; Pyridoxamine; Pyruvic Acid; Salts; Serine; Transaminases | 1998 |
Antithrombin cambridge II (Ala384Ser): clinical, functional and haplotype analysis of 18 families.
Topics: Alanine; Antithrombin III; Antithrombin III Deficiency; Female; Haplotypes; Humans; Male; Point Mutation; Polymorphism, Genetic; Serine; Thromboembolism | 1998 |
Mutations at the Ser50 residue of translation factor eIF-2alpha dominantly affect developmental rate, body weight, and viability of Drosophila melanogaster.
Topics: Alanine; Amino Acid Substitution; Animals; Animals, Genetically Modified; Aspartic Acid; Body Weight; Drosophila melanogaster; Eukaryotic Initiation Factor-2; Female; Heat-Shock Response; Insect Proteins; Larva; Male; Mutation; RNA, Messenger; Serine; Transgenes | 1997 |
Sulfatases, trapping of the sulfated enzyme intermediate by substituting the active site formylglycine.
Topics: Alanine; Alkaline Phosphatase; Binding Sites; Catechols; Cerebroside-Sulfatase; Chondro-4-Sulfatase; Galactose; Glycine; Humans; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Serine; Sulfuric Acid Esters | 1998 |
Human melanoma patients recognize an HLA-A1-restricted CTL epitope from tyrosinase containing two cysteine residues: implications for tumor vaccine development.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cancer Vaccines; Cysteine; Cytotoxicity, Immunologic; HLA-A1 Antigen; Humans; Immunodominant Epitopes; Melanoma; Monophenol Monooxygenase; Peptide Fragments; Serine; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured | 1998 |
The carboxyl-terminal 90 residues of porcine submaxillary mucin are sufficient for forming disulfide-bonded dimers.
Topics: Alanine; Amino Acid Sequence; Animals; Cystine; Dimerization; Disulfides; Humans; Molecular Sequence Data; Mucins; Mutagenesis, Site-Directed; Sequence Homology, Amino Acid; Serine; Submandibular Gland; Swine | 1998 |
Non-canonical inteins.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Consensus Sequence; Conserved Sequence; Cyanobacteria; Cysteine; Databases as Topic; Methanococcus; Molecular Sequence Data; Open Reading Frames; Peptide Library; Protein Splicing; Sequence Alignment; Sequence Homology, Amino Acid; Serine | 1998 |
Urinary excretion of D-serine in human: comparison of different ages and species.
Topics: Adult; Aging; Alanine; Animal Feed; Animals; Child; Chromatography, High Pressure Liquid; Colostrum; Dogs; Humans; Infant; Male; Rats; Rats, Wistar; Serine | 1998 |
Consequences of the loss of O-linked glycosylation of meningococcal type IV pilin on piliation and pilus-mediated adhesion.
Topics: Adenocarcinoma; Alanine; Amino Acid Sequence; Bacterial Adhesion; Bacterial Outer Membrane Proteins; Fimbriae Proteins; Fimbriae, Bacterial; Glycosylation; Humans; Molecular Sequence Data; Mutation; Neisseria meningitidis; Serine; Tumor Cells, Cultured | 1998 |
Phosphorylation of the kinase homology domain is essential for activation of the A-type natriuretic peptide receptor.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Atrial Natriuretic Factor; Binding Sites; Cell Line; Enzyme Activation; Glutamic Acid; Guanylate Cyclase; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Octoxynol; Peptide Mapping; Phosphopeptides; Phosphorylation; Receptors, Atrial Natriuretic Factor; Sequence Homology, Amino Acid; Serine; Threonine; Transfection | 1998 |
Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102.
Topics: Alanine; Alkaline Phosphatase; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Phosphates; Protein Conformation; Serine | 1998 |
Loop closure and intersubunit communication in tryptophan synthase.
Topics: Alanine; Allosteric Site; Crystallography, X-Ray; Enzyme Activation; Ligands; Models, Molecular; Protein Structure, Secondary; Protein Structure, Tertiary; Salmonella typhimurium; Serine; Structure-Activity Relationship; Tryptophan Synthase | 1998 |
[Synthesis of new chromogenic substrates for aspartyl proteases].
Topics: Alanine; Aspartic Acid Endopeptidases; Buffers; Catalysis; Chromogenic Compounds; Diatomaceous Earth; Enzymes, Immobilized; Osmolar Concentration; Pepsin A; Serine; Solvents; Substrate Specificity | 1998 |
Serine-70 is one of the critical sites for drug-induced Bcl2 phosphorylation in cancer cells.
Topics: Alanine; Antineoplastic Agents; Apoptosis; Depsipeptides; Humans; Mutagenesis, Site-Directed; Nocodazole; Okadaic Acid; Oligopeptides; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Serine; Tumor Cells, Cultured | 1998 |
Computer modelling of dynamics of Ser92X deoxymyoglobin mutants.
Topics: Alanine; Animals; Computer Simulation; Crystallography, X-Ray; Humans; Isoleucine; Models, Molecular; Myoglobin; Point Mutation; Protein Conformation; Serine; Threonine; Valine; Whales | 1998 |
Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components.
Topics: Alanine; Amino Acid Substitution; Animals; Annexin A5; Crystallography, X-Ray; DNA Mutational Analysis; Liposomes; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Partial Thromboplastin Time; Phosphatidylcholines; Phosphatidylserines; Rats; Serine; Threonine | 1998 |
[Determination of activity of aspartic proteinases by cleavage of new chromogenic substrates].
Topics: Alanine; Aspartic Acid Endopeptidases; Chromogenic Compounds; Chymosin; Dinitrophenols; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Oligopeptides; Pepsin A; Serine; Spectrophotometry, Ultraviolet; Substrate Specificity | 1998 |
Identification and characterization of the major phosphorylation sites of the B-type natriuretic peptide receptor.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Glycine; Guanylate Cyclase; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphorylation; Receptors, Atrial Natriuretic Factor; Serine; Structure-Activity Relationship; Threonine | 1998 |
Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Animals; Biological Transport; CHO Cells; Cricetinae; Enzyme Activation; Glucose; Glucose Transporter Type 4; Insulin; Mice; Molecular Sequence Data; Monosaccharide Transport Proteins; Muscle Proteins; Mutagenesis, Site-Directed; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Ribosomal Protein S6 Kinases; Serine; Threonine | 1998 |
Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Core Binding Factor Alpha 1 Subunit; COS Cells; Dimerization; DNA-Binding Proteins; Glutamine; Mice; Molecular Sequence Data; Neoplasm Proteins; Nuclear Localization Signals; Proline; Proto-Oncogene Proteins c-myc; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Threonine; Transcription Factor AP-2; Transcription Factors; Transcriptional Activation | 1998 |
Mutational analysis of structural features of rat hormone-sensitive lipase.
Topics: Alanine; Animals; Cell Line; CHO Cells; Computer Simulation; Cricetinae; DNA Mutational Analysis; Enzyme Activation; Mutagenesis, Site-Directed; Rats; Serine; Sterol Esterase; Transfection | 1998 |
Identification of the catalytic triad of the protein D2 protease in Pseudomonas aeruginosa.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Carbapenems; Catalysis; Endopeptidases; Glutamine; Histidine; Imipenem; Ion Channels; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Porins; Pseudomonas aeruginosa; Serine | 1998 |
Lanthionine macrocyclization by in situ activation of serine.
Topics: Alanine; Amino Acids, Cyclic; Chromatography, High Pressure Liquid; Molecular Structure; Sequence Analysis; Serine; Sulfides | 1998 |
Steady-state plasma membrane expression of human cytomegalovirus gB is determined by the phosphorylation state of Ser900.
Topics: Alanine; Animals; Antibodies, Monoclonal; Antifungal Agents; Aspartic Acid; Biological Transport; Cell Line; Cell Membrane; Cytomegalovirus; Cytoplasm; Enzyme Inhibitors; Gene Expression; Humans; Phosphoprotein Phosphatases; Phosphorylation; Pyrans; Rabbits; Serine; Spiro Compounds; Tumor Cells, Cultured; Viral Envelope Proteins | 1998 |
Mutation of individual serine residues in the C-terminal tail of the lutropin/choriogonadotropin receptor reveal distinct structural requirements for agonist-induced uncoupling and agonist-induced internalization.
Topics: Alanine; Animals; Arrestin; Cell Line; Chorionic Gonadotropin; Clone Cells; Cyclic AMP; Dynamins; GTP Phosphohydrolases; Humans; Mutagenesis, Site-Directed; Phosphorylation; Rats; Receptors, LH; Serine; Structure-Activity Relationship; Transfection; Uncoupling Agents | 1998 |
Functional significance of cysteine residues in the delta opioid receptor studied by site-directed mutagenesis.
Topics: Alanine; Amino Acid Sequence; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cysteine; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Receptors, Opioid, delta; Serine | 1998 |
Cysteine 42 is important for maintaining an integral active site for O-acetylserine sulfhydrylase resulting in the stabilization of the alpha-aminoacrylate intermediate.
Topics: Alanine; Binding Sites; Circular Dichroism; Cysteine; Cysteine Synthase; Deuterium; Enzyme Activation; Enzyme Stability; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Insertional; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1998 |
Dramatic differences in the binding of UDP-galactose and UDP-glucose to UDP-galactose 4-epimerase from Escherichia coli.
Topics: Alanine; Binding Sites; Crystallography, X-Ray; Escherichia coli; Models, Molecular; Mutagenesis, Insertional; NAD; Phenylalanine; Serine; Tyrosine; UDPglucose 4-Epimerase; Uridine Diphosphate Galactose; Uridine Diphosphate Glucose | 1998 |
Effects of the cys mutations on structure and function of the ATP-dependent HslVU protease in Escherichia coli. The Cys287 to Val mutation in HslU uncouples the ATP-dependent proteolysis by HslvU from ATP hydrolysis.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; ATP-Dependent Proteases; Cysteine; Endopeptidases; Escherichia coli; Ethylmaleimide; Heat-Shock Proteins; Hydrolysis; Mutagenesis, Site-Directed; Protein Conformation; Serine; Serine Endopeptidases; Substrate Specificity; Valine | 1998 |
Mutational analysis of the carboxy-terminal phosphorylation site of GLUT-4 in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Alanine; Amino Acid Sequence; Animals; Glucose Transporter Type 3; Glucose Transporter Type 4; Humans; Leucine; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Phosphorylation; Point Mutation; Recombinant Fusion Proteins; Serine; Transfection | 1998 |
Active serine involved in the stabilization of the active site loop in the Humicola lanuginosa lipase.
Topics: Alanine; Binding Sites; Dimyristoylphosphatidylcholine; Enzyme Stability; Lipase; Liposomes; Mitosporic Fungi; Models, Molecular; Mutagenesis, Site-Directed; Phosphatidylglycerols; Protein Structure, Secondary; Serine; Spectrometry, Fluorescence; Thermodynamics | 1998 |
cAMP-dependent phosphorylation sites and macroscopic activity of recombinant cardiac L-type calcium channels.
Topics: Alanine; Amino Acid Substitution; Barium; Binding Sites; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dihydropyridines; Humans; Kidney; Membrane Proteins; Muscle Proteins; Mutagenesis, Site-Directed; Myocardium; Patch-Clamp Techniques; Phosphorylation; Recombinant Proteins; Serine; Transfection | 1998 |
Posttranslational formation of formylglycine in prokaryotic sulfatases by modification of either cysteine or serine.
Topics: Alanine; Arylsulfatases; Bacterial Proteins; Binding Sites; Borohydrides; Cysteine; Glycine; Klebsiella pneumoniae; Mutagenesis, Site-Directed; Peptide Fragments; Prokaryotic Cells; Protein Processing, Post-Translational; Pseudomonas aeruginosa; Recombinant Proteins; Sequence Analysis; Serine; Sulfates; Trypsin | 1998 |
Synthesis and characterization of more potent analogues of hirudin fragment 1-47 containing non-natural amino acids.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Cattle; Circular Dichroism; Glycine; Hirudins; Humans; Molecular Sequence Data; Peptide Fragments; Phenylalanine; Serine; Spectrometry, Fluorescence; Thrombin; Tyrosine; Valine | 1998 |
Stepwise subunit interaction changes by mono- and bisphosphorylation of cardiac troponin I.
Topics: Alanine; Binding Sites; Cyclic AMP-Dependent Protein Kinases; Humans; Mutagenesis, Site-Directed; Myocardium; Phosphorylation; Protein Conformation; Recombinant Proteins; Serine; Substrate Specificity; Troponin I | 1998 |
Catalytic competence of O-acetylserine sulfhydrylase in the crystal probed by polarized absorption microspectrophotometry.
Topics: Alanine; Catalysis; Crystallization; Cysteine; Cysteine Synthase; Hydrogen-Ion Concentration; Microspectrophotometry; Models, Chemical; Salmonella typhimurium; Serine; Sodium Azide; Structure-Activity Relationship | 1998 |
Tryptophan synthase mutations that alter cofactor chemistry lead to mechanism-based inactivation.
Topics: Alanine; Aspartic Acid; Bacterial Proteins; Catalysis; Circular Dichroism; Enzyme Activation; Multienzyme Complexes; Mutagenesis, Site-Directed; Peptide Fragments; Pyridoxal Phosphate; Serine; Spectrometry, Fluorescence; Substrate Specificity; Tryptophan Synthase | 1998 |
Effect of exceptional valine replacement for highly conserved alanine-55 on the catalytic site structure of chymotrypsin-like serine protease.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cattle; Chymotrypsin; Histidine; Models, Molecular; Molecular Sequence Data; Protein C; Protein Conformation; Sequence Alignment; Serine; Threonine; Valine | 1998 |
Substitution of alanine for serine 250 in the murine fatty acid transport protein inhibits long chain fatty acid transport.
Topics: 3T3 Cells; Adenosine Triphosphate; Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Azides; Biological Transport; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Carrier Proteins; Cloning, Molecular; Cyanides; DNA, Complementary; Fatty Acid Transport Proteins; Fatty Acids; Membrane Proteins; Membrane Transport Proteins; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Sequence Homology, Amino Acid; Serine | 1998 |
Identification of the veratryl alcohol binding site in lignin peroxidase by site-directed mutagenesis.
Topics: Alanine; Amino Acid Substitution; Bacterial Proteins; Benzyl Alcohols; Binding Sites; Escherichia coli; Glutamic Acid; Hemeproteins; Kinetics; Mutagenesis, Site-Directed; Peroxidases; Recombinant Proteins; Serine | 1998 |
m-Calpain subunits remain associated in the presence of calcium.
Topics: Alanine; Animals; Calcium; Calpain; Caseins; Catalytic Domain; Cattle; Cysteine; Dimerization; Glutamic Acid; Kinetics; Macromolecular Substances; Mutagenesis, Site-Directed; Protein Binding; Recombinant Proteins; Serine | 1998 |
Attenuated neurotransmitter release and spreading depression-like depolarizations after focal ischemia in mutant mice with disrupted type I nitric oxide synthase gene.
Topics: Alanine; Animals; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Cortical Spreading Depression; Ethanolamines; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Laser-Doppler Flowmetry; Male; Membrane Potentials; Mice; Mice, Knockout; Microdialysis; Nerve Tissue Proteins; Neurotoxins; Neurotransmitter Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Serine; Taurine | 1998 |
Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Caseins; COS Cells; DNA; DNA-Binding Proteins; Genes, Reporter; Milk Proteins; Molecular Sequence Data; Phosphoamino Acids; Phosphorylation; Prolactin; Proline; Serine; STAT5 Transcription Factor; Structure-Activity Relationship; Trans-Activators; Transcriptional Activation | 1998 |
Interaction of insulin receptor substrate-1 (IRS-1) with phosphatidylinositol 3-kinase: effect of substitution of serine for alanine in potential IRS-1 serine phosphorylation sites.
Topics: Alanine; Amino Acid Substitution; Insulin Receptor Substrate Proteins; Isoenzymes; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Tyrosine; Yeasts | 1998 |
Detection of more than 91% cystic fibrosis mutations in a sample of the population from Reunion Island and identification of two novel mutations (A309G, S1255L) and one novel polymorphism (L49L)
Topics: Alanine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; France; Glycine; Humans; Leucine; Mutation, Missense; Polymorphism, Genetic; Serine | 1998 |
Novel role of phosphorylation in Fe-S cluster stability revealed by phosphomimetic mutations at Ser-138 of iron regulatory protein 1.
Topics: Aconitate Hydratase; Aerobiosis; Alanine; Amino Acid Substitution; Anaerobiosis; Aspartic Acid; Binding Sites; Cytosol; Escherichia coli; Glutamic Acid; Iron Regulatory Protein 1; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Isoenzymes; Kinetics; Mutagenesis, Site-Directed; Phosphorylation; Protein Processing, Post-Translational; Recombinant Proteins; RNA-Binding Proteins; Serine | 1998 |
Ser752 mutation to Pro or Ala in the beta3 integrin subunit differentially affects the kinetics of cell spreading to von Willebrand factor and fibrinogen.
Topics: Alanine; Animals; Antigens, CD; Cell Adhesion; Cell Count; Cell Line; Cricetinae; Cytoskeleton; Fibrinogen; Humans; Image Processing, Computer-Assisted; Integrin beta3; Kinetics; Platelet Membrane Glycoproteins; Point Mutation; Proline; Serine; von Willebrand Factor | 1998 |
Complete amino acid sequences and phosphorylation sites, determined by Edman degradation and mass spectrometry, of rat parotid destrin- and cofilin-like proteins.
Topics: Actin Depolymerizing Factors; Alanine; Amino Acid Sequence; Animals; Carrier Proteins; Cyanogen Bromide; Cytoskeletal Proteins; Destrin; DNA, Complementary; Endopeptidases; Male; Mass Spectrometry; Metalloendopeptidases; Methionine; Microfilament Proteins; Molecular Sequence Data; Molecular Weight; Parotid Gland; Phosphorylation; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Cholinergic; Salivary Proteins and Peptides; Serine; Swine | 1998 |
Contribution to Tl+, K+, and Na+ binding of Asn776, Ser775, Thr774, Thr772, and Tyr771 in cytoplasmic part of fifth transmembrane segment in alpha-subunit of renal Na,K-ATPase.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Binding Sites; Cytoplasm; Hydroxides; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Potassium; Protein Structure, Tertiary; Recombinant Proteins; Serine; Sodium; Sodium-Potassium-Exchanging ATPase; Swine; Thallium; Threonine; Tyrosine | 1998 |
Effects of complementarity determining region mutations on the affinity of an alpha/beta T cell receptor: measuring the energy associated with CD4/CD8 repertoire skewing.
Topics: Alanine; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Gene Rearrangement, T-Lymphocyte; Histocompatibility Antigens Class I; Ligands; Models, Immunological; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Peptides; Protein Binding; Receptors, Antigen; Receptors, Antigen, T-Cell, alpha-beta; Serine; Thermodynamics | 1999 |
Importance of conserved cysteines in the extracellular loops of human PACAP/VIP1 receptor for ligand binding and stimulation of cAMP production.
Topics: Alanine; Amino Acid Substitution; Binding, Competitive; Cell Line; Cell Membrane; Conserved Sequence; Cyclic AMP; Cysteine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone; Receptors, Vasoactive Intestinal Peptide; Receptors, Vasoactive Intestinal Polypeptide, Type I; Recombinant Proteins; Serine; Transfection; Vasoactive Intestinal Peptide | 1998 |
Phosphorylation of either crh or HPr mediates binding of CcpA to the bacillus subtilis xyn cre and catabolite repression of the xyn operon.
Topics: Alanine; Amino Acid Substitution; Bacillus subtilis; Bacterial Proteins; Base Sequence; beta-Glucosidase; DNA-Binding Proteins; Endo-1,4-beta Xylanases; Feedback; Fructosediphosphates; Gene Expression Regulation, Bacterial; Macromolecular Substances; Molecular Sequence Data; Operon; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphoproteins; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Processing, Post-Translational; Repressor Proteins; Serine; Transcription, Genetic; Xylosidases | 1999 |
Conformational unfolding studies of three-disulfide mutants of bovine pancreatic ribonuclease A and the coupling of proline isomerization to disulfide redox reactions.
Topics: Alanine; Amino Acid Substitution; Animals; Cattle; Cysteine; Disulfides; Mutagenesis, Site-Directed; Oxidation-Reduction; Proline; Protein Conformation; Protein Folding; Protein Isoforms; Ribonuclease, Pancreatic; Serine; Spectrometry, Fluorescence; Spectrophotometry | 1999 |
Nuclear import of the Drosophila Rel protein Dorsal is regulated by phosphorylation.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Biological Transport; Cell Nucleus; Cytoplasm; DNA-Binding Proteins; Drosophila; Drosophila Proteins; Female; Molecular Sequence Data; Mutagenesis; Nuclear Proteins; Phosphoproteins; Phosphorylation; Sequence Homology, Amino Acid; Serine; Signal Transduction; Transcription Factors | 1999 |
cdk1- and cdk2-mediated phosphorylation of MyoD Ser200 in growing C2 myoblasts: role in modulating MyoD half-life and myogenic activity.
Topics: Alanine; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Differentiation; Cell Division; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Half-Life; Muscle, Skeletal; MyoD Protein; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Stem Cells; Transcriptional Activation | 1999 |
Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis.
Topics: Alanine; Amino Acid Substitution; Apoptosis; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Cytosol; Female; Humans; JNK Mitogen-Activated Protein Kinases; Mitochondria; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Paclitaxel; Phosphorylation; Point Mutation; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Sequence Deletion; Serine; Signal Transduction; Transfection; Tumor Cells, Cultured; Vincristine | 1999 |
Raman markers of nonaromatic side chains in an alpha-helix assembly: Ala, Asp, Glu, Gly, Ile, Leu, Lys, Ser, and Val residues of phage fd subunits.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Deuterium; DNA, Single-Stranded; Glutamic Acid; Glycine; Inovirus; Isoleucine; Lysine; Molecular Sequence Data; Protein Structure, Secondary; Serine; Spectrum Analysis, Raman; Valine; Viral Proteins; Virus Assembly | 1999 |
Modulating electron density in the bound product, 4-hydroxybenzoyl-CoA, by mutations in 4-chlorobenzoyl-CoA dehalogenase near the 4-hydroxy group.
Topics: Acyl Coenzyme A; Alanine; Aspartic Acid; Binding Sites; Electrons; Glutamic Acid; Hydrolases; Models, Chemical; Mutagenesis, Site-Directed; Protein Binding; Pseudomonas; Serine; Spectrum Analysis, Raman | 1999 |
Dual specificity protein kinase activity of testis-specific protein kinase 1 and its regulation by autophosphorylation of serine-215 within the activation loop.
Topics: Alanine; Animals; Base Sequence; Catalytic Domain; COS Cells; DNA Primers; Enzyme Activation; Glutamic Acid; HeLa Cells; Humans; Mutagenesis, Site-Directed; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Serine; Substrate Specificity | 1999 |
Crystal structure of histidine ammonia-lyase revealing a novel polypeptide modification as the catalytic electrophile.
Topics: Alanine; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Energy Transfer; Histidine Ammonia-Lyase; Models, Molecular; Peptides; Protein Folding; Protein Structure, Secondary; Pseudomonas putida; Serine | 1999 |
Active sites of diacylglycerol kinase from Escherichia coli are shared between subunits.
Topics: Alanine; Asparagine; Aspartic Acid; Binding Sites; Circular Dichroism; Diacylglycerol Kinase; Enzyme Activation; Escherichia coli; Genetic Complementation Test; Glutamine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Serine; Structure-Activity Relationship | 1999 |
Mechanistic insights into p-hydroxybenzoate hydroxylase from studies of the mutant Ser212Ala.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Alanine; Catalysis; Mutation; Oxidation-Reduction; Pseudomonas fluorescens; Serine | 1999 |
The iron sulfur protein AtsB is required for posttranslational formation of formylglycine in the Klebsiella sulfatase.
Topics: Alanine; Bacterial Proteins; Borohydrides; Cloning, Molecular; Escherichia coli; Gene Expression Regulation, Bacterial; Glycine; Iron-Sulfur Proteins; Klebsiella pneumoniae; Molecular Sequence Data; Protein Processing, Post-Translational; Recombinant Proteins; Serine; Sulfatases; Transfection | 1999 |
Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six Ser --> Ala mutants.
Topics: Alanine; Calorimetry, Differential Scanning; Crystallography, X-Ray; Energy Transfer; Enzyme Stability; Humans; Hydrogen Bonding; Models, Molecular; Muramidase; Mutagenesis, Site-Directed; Protein Conformation; Serine; Structure-Activity Relationship; Thermodynamics | 1999 |
Site-directed mutagenesis of the cysteine ligands to the [4Fe-4S] cluster of Escherichia coli MutY.
Topics: Alanine; Cell Fractionation; Cysteine; DNA Glycosylases; DNA Repair; DNA, Bacterial; Enzyme Activation; Enzyme Stability; Escherichia coli; Histidine; Iron-Sulfur Proteins; Ligands; Models, Molecular; Mutagenesis, Site-Directed; N-Glycosyl Hydrolases; Protein Binding; Recombinant Proteins; Serine | 1999 |
Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.
Topics: Alanine; Animals; Apoptosis; Binding Sites; Cell Transformation, Neoplastic; DNA; Gene Expression; Humans; Mice; Mutagenesis, Site-Directed; Serine; Transcription, Genetic; Transcriptional Activation; Tumor Suppressor Protein p53 | 1999 |
Alanine-23 of transducin alpha subunit is involved in defining the affinity for betagammma complex.
Topics: Adenylyl Cyclases; Alanine; Amino Acid Substitution; Cell Line; GTP-Binding Proteins; Humans; Models, Molecular; Mutation; Peptide Fragments; Serine; Stimulation, Chemical; Transducin | 1999 |
Substitution of the two carboxyl-terminal serines by alanine causes retention of MAL, a component of the apical sorting machinery, in the endoplasmic reticulum.
Topics: Alanine; Animals; Calcium-Binding Proteins; Calnexin; Caveolin 1; Caveolins; CD4 Antigens; Cells, Cultured; COS Cells; Endoplasmic Reticulum; Humans; Hybridomas; Membrane Proteins; Membrane Transport Proteins; Mice; Mutagenesis; Myelin and Lymphocyte-Associated Proteolipid Proteins; Myelin Proteins; Proteolipids; Serine | 1999 |
Identification of Ser424 as the protein kinase A phosphorylation site in CTP synthetase from Saccharomyces cerevisiae.
Topics: Alanine; Animals; Carbon-Nitrogen Ligases; Cattle; Cyclic AMP-Dependent Protein Kinases; Cytidine Triphosphate; Enzyme Inhibitors; Kinetics; Mutagenesis, Site-Directed; Oligopeptides; Phosphorylation; Recombinant Proteins; Saccharomyces cerevisiae; Serine; Substrate Specificity | 1999 |
Ala99ser mutation in RI alpha regulatory subunit of protein kinase A causes reduced kinase activation by cAMP and arrest of hormone-dependent breast cancer cell growth.
Topics: Alanine; Amino Acid Substitution; Apoptosis; Breast Neoplasms; Cell Division; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Humans; Isoenzymes; Mutagenesis, Site-Directed; Neoplasms, Hormone-Dependent; Serine; Transfection; Tumor Cells, Cultured | 1999 |
Phosphorylation and/or presence of serine 37 in the movement protein of tomato mosaic tobamovirus is essential for intracellular localization and stability in vivo.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Binding Sites; Fluorescence; Glutamic Acid; Green Fluorescent Proteins; Intracellular Fluid; Luminescent Proteins; Molecular Sequence Data; Mutagenesis; Nicotiana; Phosphoamino Acids; Phosphorylation; Plant Viral Movement Proteins; Plants, Toxic; Protoplasts; Recombinant Fusion Proteins; Serine; Solanum lycopersicum; Threonine; Tobamovirus; Viral Proteins | 1999 |
Shutoff and agonist-triggered internalization of protease-activated receptor 1 can be separated by mutation of putative phosphorylation sites in the cytoplasmic tail.
Topics: Alanine; Amino Acid Sequence; Animals; beta-Adrenergic Receptor Kinases; Cell Line; COS Cells; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; G-Protein-Coupled Receptor Kinase 2; G-Protein-Coupled Receptor Kinase 3; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Peptide Mapping; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Receptor Protein-Tyrosine Kinases; Receptor, PAR-1; Receptors, Thrombin; Recombinant Proteins; Serine; Signal Transduction | 1999 |
Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists.
Topics: Alanine; Animals; Binding Sites; COS Cells; Drug Design; Escherichia coli; HeLa Cells; Humans; Isomerism; Keratolytic Agents; Models, Molecular; Receptors, Retinoic Acid; Recombinant Proteins; Retinoids; Saccharomyces cerevisiae; Serine; Transcriptional Activation; Tretinoin | 1999 |
Modulation by L- and D-isoforms of amino acids of the L-glutamate response of N-methyl-D-aspartate receptors.
Topics: Alanine; Amino Acids; Animals; Computer Simulation; Female; Glutamic Acid; Ligands; Membrane Potentials; Oocytes; Protein Isoforms; Receptors, N-Methyl-D-Aspartate; Serine; Software; Stereoisomerism; Xenopus laevis | 1999 |
Role of ser-237 in the substrate specificity of the carbapenem-hydrolyzing class A beta-lactamase Sme-1.
Topics: Alanine; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Enterobacteriaceae; Escherichia coli; Hydrolysis; Imipenem; Mutagenesis, Site-Directed; Mutation; Serine; Substrate Specificity | 1999 |
The free energies for mutating S27 and W79 to alanine in streptavidin and its biotin complex: the relative size of polar and nonpolar free energies on biotin binding.
Topics: Alanine; Amino Acid Substitution; Biotin; Computer Simulation; Mutation; Protein Binding; Serine; Static Electricity; Streptavidin; Thermodynamics; Tryptophan | 1999 |
D-configuration of serine is crucial in maintaining the phalloidin-like conformation of viroisin.
Topics: Actins; Alanine; Amino Acid Substitution; Animals; Binding Sites; Biological Assay; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Phalloidine; Protein Conformation; Rabbits; Serine; Structure-Activity Relationship | 1999 |
Hydrogen bonding modulates binding of exogenous ligands in a myoglobin proximal cavity mutant.
Topics: Alanine; Amino Acid Substitution; Animals; Binding Sites; Glycine; Histidine; Hydrogen Bonding; Imidazoles; Ligands; Macromolecular Substances; Metmyoglobin; Models, Chemical; Mutagenesis, Insertional; Myoglobin; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; Protons; Serine; Threonine; Whales | 1999 |
Relationship between the conserved alpha subunit arginine 107 and effects of phosphate on the activity and stability of Vibrio harveyi luciferase.
Topics: Alanine; Amino Acid Sequence; Arginine; Conserved Sequence; Glutamic Acid; Kinetics; Luciferases; Macromolecular Substances; Mutagenesis, Site-Directed; Phosphates; Recombinant Proteins; Serine; Vibrio | 1999 |
Ser203 as well as Ser204 and Ser207 in fifth transmembrane domain of the human beta2-adrenoceptor contributes to agonist binding and receptor activation.
Topics: Adrenergic alpha-Agonists; Alanine; Amino Acid Substitution; Animals; CHO Cells; Cricetinae; Humans; Isoproterenol; Kinetics; Mutation; Rats; Receptors, Adrenergic, alpha-2; Serine | 1999 |
Localization of L-glutamate and glutamate-like receptors at the squid giant synapse.
Topics: Alanine; Animals; Antibody Specificity; Aspartic Acid; Blotting, Western; Chromatography, High Pressure Liquid; Decapodiformes; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Glutamic Acid; Glycine; Receptors, Glutamate; Serine; Synapses; Taurine | 1999 |
Identification of two serine residues involved in catalysis by fatty acid amide hydrolase.
Topics: Alanine; Amidohydrolases; Amino Acid Sequence; Animals; Binding Sites; Catalysis; COS Cells; Cysteine; Isoflurophate; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phospholipases A; Protease Inhibitors; Serine; Sulfhydryl Compounds | 1999 |
Catalytic mechanism of the tryptophan synthase alpha(2)beta(2) complex. Effects of pH, isotopic substitution, and allosteric ligands.
Topics: Alanine; Allosteric Regulation; Catalytic Domain; Deuterium; Glycine; Hydrogen-Ion Concentration; Indoles; Ligands; Models, Chemical; Oxindoles; Pyridoxal Phosphate; Salmonella typhimurium; Serine; Tryptophan Synthase | 1999 |
Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases.
Topics: Acetophenones; Alanine; Amino Acids; Animals; Arachidonic Acids; Aspartic Acid; Brain Edema; Cerebral Cortex; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dimethyl Sulfoxide; Enzyme Inhibitors; Estrenes; Ethanolamines; Fatty Acids, Unsaturated; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hypotonic Solutions; Male; Osmotic Pressure; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Protein Kinase C; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Serine; Solvents; Taurine; Water-Electrolyte Balance | 1999 |
Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase.
Topics: Alanine; Amino Acid Substitution; Cyclic AMP-Dependent Protein Kinases; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Chemical; Mutagenesis, Site-Directed; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein Tyrosine Phosphatases, Non-Receptor; Recombinant Proteins; Serine; Signal Transduction; Substrate Specificity | 1999 |
Identification and characterization of the phosphorylation sites of the guanylyl cyclase-linked natriuretic peptide receptors A and B.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Cell Line; Glutamic Acid; Guanylate Cyclase; Humans; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphoproteins; Phosphorylation; Receptors, Atrial Natriuretic Factor; Recombinant Proteins; Serine; Threonine | 1999 |
Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation.
Topics: Alanine; Apoptosis; Chloramphenicol O-Acetyltransferase; DNA Damage; Flow Cytometry; Humans; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plasmids; Serine; Time Factors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ultraviolet Rays | 1999 |
Extensive post-translational modification, including serine to D-alanine conversion, in the two-component lantibiotic, lacticin 3147.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Bacterial Proteins; Bacteriocins; Chromatography, High Pressure Liquid; Mass Spectrometry; Molecular Sequence Data; Protein Processing, Post-Translational; Serine | 1999 |
Effect of multiple serine/alanine mutations in the transmembrane spanning region V of the D2 dopamine receptor on ligand binding.
Topics: Alanine; Amino Acid Substitution; Animals; Binding, Competitive; COS Cells; Dopamine Agonists; Dopamine Antagonists; Ligands; Mutation; Receptors, Dopamine D2; Serine | 2000 |
Hyperglycemia enhances extracellular glutamate accumulation in rats subjected to forebrain ischemia.
Topics: Alanine; Animals; Brain Ischemia; Glutamic Acid; Glutamine; Glycine; Hyperglycemia; Male; Prosencephalon; Rats; Rats, Wistar; Serine; Taurine | 2000 |
New transthyretin variants SER 91 and SER 116 associated with familial amyloidotic polyneuropathy. Mutations in brief no. 151. Online.
Topics: Aged; Alanine; Amyloid Neuropathies; Humans; Male; Mutation; Prealbumin; Protein Isoforms; Serine; Tyrosine | 1998 |
The utilization of alanine, glutamic acid, and serine as amino acid substrates for glycine N-acyltransferase.
Topics: Acyltransferases; Alanine; Animals; Cattle; Glutamic Acid; Glycine; Humans; Kinetics; Serine | 2000 |
Activation of protein kinase D by signaling through the alpha subunit of the heterotrimeric G protein G(q).
Topics: Alanine; Aluminum Compounds; Animals; Blotting, Western; Bombesin; COS Cells; Enzyme Activation; Enzyme Inhibitors; Fluorides; Green Fluorescent Proteins; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Indoles; Luminescent Proteins; Maleimides; Mutagenesis, Site-Directed; Precipitin Tests; Protein Kinase C; Receptors, Bombesin; Recombinant Fusion Proteins; Serine; Signal Transduction; Transfection | 2000 |
Evidence that serine 304 is not a key ligand-binding residue in the active site of cytochrome P450 2D6.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Binding Sites; Catalytic Domain; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Enzyme Inhibitors; Kinetics; Ligands; Metoprolol; Mutagenesis, Site-Directed; Oxidation-Reduction; Propranolol; Quinidine; Quinine; Serine; Substrate Specificity; Yeasts | 2000 |
Differential recognition of snake venom proteins expressing specific Arg-Gly-Asp (RGD) sequence motifs by wild-type and variant integrin alphaIIbbeta3: further evidence for distinct sites of RGD ligand recognition exhibiting negative allostery.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Elapid Venoms; Humans; Models, Molecular; Molecular Sequence Data; Oligopeptides; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Fusion Proteins; Serine; Snake Venoms | 2000 |
Effects of glyphosate and dalapon on total free amino acid profiles of Pseudosuccinea columella snails.
Topics: Alanine; Amino Acids; Animals; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Glyphosate; Herbicides; Propionates; Serine; Snails; Threonine | 2000 |
The extracellular domain of herpes simplex virus gE is sufficient for accumulation at cell junctions but not for cell-to-cell spread.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Biological Transport; Chlorocebus aethiops; Epithelial Cells; Glycoproteins; Herpesvirus 1, Human; Intercellular Junctions; Molecular Sequence Data; Phosphorylation; Point Mutation; Serine; Subcellular Fractions; Vero Cells; Viral Envelope Proteins; Virion | 2000 |
Differential effect of structural modification of human dopamine transporter on the inward and outward transport of dopamine.
Topics: Alanine; Amino Acid Substitution; Biological Transport; Carrier Proteins; Cells, Cultured; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Mutagenesis; Nerve Tissue Proteins; Protein Conformation; Serine; Tyramine | 2000 |
Presence of 2-furoylmethyl derivatives in hydrolysates of processed tomato products.
Topics: Alanine; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Freeze Drying; Furans; gamma-Aminobutyric Acid; Glutamic Acid; Hydrolysis; Lysine; Maillard Reaction; Serine; Solanum lycopersicum; Threonine | 2000 |
An engineered blockage within the ammonia tunnel of carbamoyl phosphate synthetase prevents the use of glutamine as a substrate but not ammonia.
Topics: Alanine; Ammonia; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carbamyl Phosphate; Escherichia coli; Glutamic Acid; Glutamine; Glycine; Kinetics; Lysine; Methionine; Mutagenesis, Site-Directed; Phenylalanine; Serine; Substrate Specificity; Time Factors | 2000 |
Sample optimization and identification of signal patterns of amino acid side chains in 2D RFDR spectra of the alpha-spectrin SH3 domain.
Topics: Alanine; Amino Acids; Carbon Isotopes; Chemical Precipitation; Isoleucine; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Proline; Protein Conformation; Serine; Spectrin; src Homology Domains; Threonine; Valine | 2000 |
Structure of the Ser195Ala mutant of human alpha--thrombin complexed with fibrinopeptide A(7--16): evidence for residual catalytic activity.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Crystallography, X-Ray; Fibrinopeptide A; Hirudins; Humans; Models, Molecular; Peptide Fragments; Point Mutation; Protein Conformation; Serine; Software; Thrombin | 2000 |
Crystallization and preliminary crystallographic studies of a new crystal form of Escherichia coli L--asparaginase II (Ser58Ala mutant).
Topics: Alanine; Amino Acid Substitution; Asparaginase; Binding Sites; Crystallization; Crystallography, X-Ray; Escherichia coli; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Serine | 2000 |
L, M and L-M hybrid cone photopigments in man: deriving lambda max from flicker photometric spectral sensitivities.
Topics: Adult; Alanine; Color Perception; Color Perception Tests; Color Vision Defects; Female; Flicker Fusion; Humans; Lens, Crystalline; Macula Lutea; Male; Photometry; Pigments, Biological; Retinal Cone Photoreceptor Cells; Rod Opsins; Serine; X Chromosome | 1999 |
Serine residues 994 and 1023/25 are important for insulin receptor kinase inhibition by protein kinase C isoforms beta2 and theta.
Topics: Adenosine Triphosphate; Alanine; Cell Line; Humans; Insulin Resistance; Isoenzymes; Phosphorylation; Point Mutation; Protein Kinase C; Receptor, Insulin; Serine; Signal Transduction; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transfection | 2000 |
Proteasome-mediated degradation of the papillomavirus E2-TA protein is regulated by phosphorylation and can modulate viral genome copy number.
Topics: Alanine; Animals; Bovine papillomavirus 1; Cattle; Cell Line; Chlorocebus aethiops; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; DNA, Viral; Gene Dosage; Genome, Viral; Lactones; Leupeptins; Multienzyme Complexes; Mutagenesis, Site-Directed; Papilloma; Papillomavirus Infections; Phosphorylation; Proteasome Endopeptidase Complex; Serine; Viral Proteins; Warts | 2000 |
Pyruvate dehydrogenase kinase from Arabidopsis thaliana: a protein histidine kinase that phosphorylates serine residues.
Topics: Alanine; Amino Acid Sequence; Arabidopsis; Aspartic Acid; DNA, Complementary; Glutamine; Histidine; Histidine Kinase; Kinetics; Mitochondria; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphoamino Acids; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Trypsin; Zea mays | 2000 |
Evolution of C4 phosphoenolpyruvate carboxylase in Flaveria, a conserved serine residue in the carboxyl-terminal part of the enzyme is a major determinant for C4-specific characteristics.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Biological Evolution; Isoenzymes; Kinetics; Magnoliopsida; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoenolpyruvate Carboxylase; Plasmids; Protein Structure, Secondary; Recombinant Fusion Proteins; Serine; Substrate Specificity | 2000 |
Prolonged stationary-phase incubation selects for lrp mutations in Escherichia coli K-12.
Topics: Alanine; Alleles; Bacterial Proteins; Carbon; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Leucine; Leucine-Responsive Regulatory Protein; Mutation; Phenotype; Selection, Genetic; Serine; Threonine; Time Factors; Transcription Factors | 2000 |
Glycogen synthase sensitivity to insulin and glucose-6-phosphate is mediated by both NH2- and COOH-terminal phosphorylation sites.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Glucose-6-Phosphate; Glycogen Synthase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Insulin; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Rabbits; Rats; Recombinant Proteins; Serine; Transfection | 2000 |
Activation of protein kinase C stimulates the dephosphorylation of natriuretic peptide receptor-B at a single serine residue: a possible mechanism of heterologous desensitization.
Topics: Alanine; Binding Sites; Blotting, Western; Cell Line; Cell Membrane; Cyclic GMP; Detergents; Enzyme Activation; Glutamic Acid; Guanylate Cyclase; Humans; Ligands; Mutagenesis, Site-Directed; Peptide Mapping; Peptides; Phosphorylation; Plasmids; Protein Binding; Protein Kinase C; Receptors, Atrial Natriuretic Factor; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 2000 |
Transthyretin Ala97Ser is associated with familial amyloidotic polyneuropathy in a Chinese-Taiwanese family.
Topics: Alanine; Amino Acid Substitution; Amyloid Neuropathies; Codon, Nonsense; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Prealbumin; Serine | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Defective Th function induced by a dominant-negative cAMP response element binding protein mutation is reversed by Bcl-2.
Topics: Alanine; Amino Acid Substitution; Animals; Cell Death; Cell Differentiation; Cell Division; Cyclic AMP Response Element-Binding Protein; Homeostasis; Interleukin-2; Interphase; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Point Mutation; Proto-Oncogene Proteins c-bcl-2; Receptors, Antigen, T-Cell; Serine; T-Lymphocytes, Helper-Inducer; Thymus Gland | 2000 |
Disparate ligand-mediated Ca(2+) responses by wild-type, mutant Ser(200)Ala and Ser(204)Ala alpha(2A)-adrenoceptor: G(alpha15) fusion proteins: evidence for multiple ligand-activation binding sites.
Topics: Adrenergic Antagonists; Alanine; Amino Acid Substitution; Animals; Binding, Competitive; Calcium; CHO Cells; Cricetinae; Heterotrimeric GTP-Binding Proteins; Ligands; Mutagenesis, Site-Directed; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Serine | 2000 |
Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8.
Topics: Alanine; Apoptosis; Binding Sites; Caspase 1; Caspase 3; Caspase 6; Caspase 7; Caspase 8; Caspase 9; Caspases; Catalysis; Escherichia coli; Fluorescent Dyes; Glycine; Humans; Kinetics; Models, Molecular; ortho-Aminobenzoates; Peptides; Protein Binding; Proteins; Recombinant Proteins; Serine; Substrate Specificity; Tyrosine | 2000 |
A role for serine-175 in modulating the molecular conformation of calponin.
Topics: Actins; Alanine; Allosteric Site; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Binding, Competitive; Brain; Calcium-Binding Proteins; Calponins; Chickens; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epitopes; Escherichia coli; Gizzard, Avian; Kinetics; Microfilament Proteins; Molecular Sequence Data; Muscle, Smooth; Phosphorylation; Protein Binding; Protein Conformation; Protein Isoforms; Protein Kinase C; Protein Structure, Tertiary; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Tropomyosin | 2000 |
Serine 121 is an essential amino acid for biotin sulfoxide reductase functionality.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Binding Sites; Biotin; Catalysis; Chromatography, High Pressure Liquid; Coenzymes; Conserved Sequence; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Factor Xa; Glutathione Transferase; Guanine Nucleotides; Iron-Sulfur Proteins; Ligands; Mass Spectrometry; Metalloproteins; Molecular Sequence Data; Molybdenum Cofactors; Mutagenesis, Site-Directed; NADP; Oxidative Stress; Oxidoreductases; Oxygen; Paraquat; Pteridines; Pterins; Recombinant Fusion Proteins; Rhodobacter sphaeroides; Sequence Homology, Amino Acid; Serine; Spectrometry, Fluorescence; Threonine; Time Factors | 2000 |
A novel mutation, Ala315Ser, in FGFR2: a gene-environment interaction leading to craniosynostosis?
Topics: Alanine; Amino Acid Sequence; Base Sequence; Craniosynostoses; DNA Primers; Environmental Exposure; Female; Humans; Infant; Male; Molecular Sequence Data; Pedigree; Point Mutation; Radiography; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Fibroblast Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Serine | 2000 |
Mechanism of phosphoanhydride cleavage by baculovirus phosphatase.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Baculoviridae; Catalysis; Cloning, Molecular; Cysteine; DNA Mutational Analysis; Dose-Response Relationship, Drug; Escherichia coli; Humans; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation, Missense; Organophosphates; Oxygen; Phosphoric Monoester Hydrolases; Phosphorus; Plasmids; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Temperature; Time Factors; Transformation, Genetic | 2000 |
CoMFA-based prediction of agonist affinities at recombinant wild type versus serine to alanine point mutated D2 dopamine receptors.
Topics: Alanine; Amino Acid Substitution; Animals; Bromocriptine; Combinatorial Chemistry Techniques; Dopamine Agonists; Models, Molecular; Pergolide; Point Mutation; Radioligand Assay; Rats; Receptors, Dopamine D2; Recombinant Proteins; Serine; Structure-Activity Relationship; Tumor Cells, Cultured | 2000 |
Membrane mechanisms for electrogenic Na(+)-independent L-alanine transport in the lizard duodenal mucosa.
Topics: Alanine; Amino Acid Transport Systems; Amino Acids; Amino Acids, Cyclic; Animals; Carrier Proteins; Cycloleucine; Duodenum; Enzyme Inhibitors; Ethylmaleimide; Female; H(+)-K(+)-Exchanging ATPase; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Kinetics; Lizards; Male; Membrane Potentials; Patch-Clamp Techniques; Protons; Serine; Sodium; Vanadates | 2000 |
Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response.
Topics: Alanine; Amino Acid Sequence; Animals; Anti-Bacterial Agents; Base Sequence; Binding Sites; Blotting, Northern; Blotting, Western; Carrier Proteins; Caseins; Cell Line; Cell Nucleus; Chromatography, High Pressure Liquid; Cloning, Molecular; COS Cells; Endoplasmic Reticulum; Escherichia coli; Fibroblasts; Heat-Shock Proteins; High-Temperature Requirement A Serine Peptidase 1; High-Temperature Requirement A Serine Peptidase 2; Hot Temperature; Humans; Membrane Proteins; Mice; Microscopy, Fluorescence; Mitochondrial Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Periplasmic Proteins; Presenilin-1; Proto-Oncogene Proteins c-jun; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Subcellular Fractions; Temperature; Time Factors; Tissue Distribution; Tunicamycin; Two-Hybrid System Techniques; Up-Regulation | 2000 |
Serine 6 of Lck tyrosine kinase: a critical site for Lck myristoylation, membrane localization, and function in T lymphocytes.
Topics: Alanine; Amino Acid Substitution; Animals; Cell Membrane; Chlorocebus aethiops; COS Cells; Humans; Jurkat Cells; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Membrane Proteins; Mice; Mutagenesis, Site-Directed; Myristic Acid; Phosphorylation; Receptors, Antigen, T-Cell; Serine; T-Lymphocytes; Transfection | 2000 |
Altering the reaction specificity of eukaryotic ornithine decarboxylase.
Topics: Alanine; Animals; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Cysteine; Decarboxylation; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Ornithine Decarboxylase; Putrescine; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity; Trypanosoma brucei brucei | 2000 |
An alternative protein splicing mechanism for inteins lacking an N-terminal nucleophile.
Topics: Alanine; Alternative Splicing; Bacterial Proteins; Carrier Proteins; Catalysis; Cell Line; Cloning, Molecular; Cysteine; Methanococcus; Models, Genetic; Mutagenesis, Site-Directed; Mutation; Polymorphism, Genetic; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Serine | 2000 |
Interaction between interferon consensus sequence-binding protein and COP9/signalosome subunit CSN2 (Trip15). A possible link between interferon regulatory factor signaling and the COP9/signalosome.
Topics: 3T3 Cells; Alanine; Animals; B-Lymphocytes; Blotting, Northern; Carrier Proteins; COP9 Signalosome Complex; COS Cells; DNA; DNA, Complementary; Dose-Response Relationship, Drug; Gene Library; Glutathione Transferase; HeLa Cells; HL-60 Cells; Humans; Interferon Regulatory Factors; Mice; Models, Biological; Multiprotein Complexes; Mutagenesis, Site-Directed; Nuclear Proteins; Peptide Hydrolases; Phosphorylation; Plasmids; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Proteins; Receptors, Thyroid Hormone; Repressor Proteins; RNA, Messenger; Serine; Signal Transduction; Transcription Factors; Transcription, Genetic; Two-Hybrid System Techniques | 2000 |
Age-related changes in aggrecan glycosylation affect cleavage by aggrecanase.
Topics: Age Factors; Aggrecans; Aging; Alanine; Animals; beta-Galactosidase; Blotting, Western; Cattle; Chondroitin Sulfates; Chondroitinases and Chondroitin Lyases; Endopeptidases; Extracellular Matrix Proteins; Freezing; Glutamine; Glycosaminoglycans; Glycoside Hydrolases; Glycosylation; Keratan Sulfate; Lectins, C-Type; Matrix Metalloproteinase 3; Phenylalanine; Proteoglycans; Serine; Time Factors | 2000 |
Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells.
Topics: Alanine; Casein Kinase II; Colonic Neoplasms; Enzyme Inhibitors; Flavonoids; GTP Phosphohydrolases; Humans; Immunoblotting; Indoles; Kinetics; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RGS Proteins; Serine; Signal Transduction; Transfection; Tumor Cells, Cultured | 2000 |
Amino acid selectivity in the aminoacylation of coenzyme A and RNA minihelices by aminoacyl-tRNA synthetases.
Topics: Alanine; Amino Acids; Amino Acyl-tRNA Synthetases; Chromatography, Thin Layer; Coenzyme A; Electrophoresis; Escherichia coli; Evolution, Molecular; Isoleucine-tRNA Ligase; Kinetics; Leucine; Lysine-tRNA Ligase; RNA; Serine; Threonine; Time Factors; Valine; Valine-tRNA Ligase | 2000 |
The role of Glu74 and Tyr82 in the reaction catalyzed by sheep liver cytosolic serine hydroxymethyltransferase.
Topics: Alanine; Amino Acid Substitution; Animals; Apoenzymes; Binding Sites; Calorimetry, Differential Scanning; Catalysis; Cytosol; Formaldehyde; Glutamic Acid; Glycine Hydroxymethyltransferase; Humans; Kinetics; Liver; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Rabbits; Recombinant Fusion Proteins; Serine; Sheep; Structure-Activity Relationship; Tetrahydrofolates; Tyrosine | 2000 |
Impaired antibody affinity maturation process characterizes a subset of patients with common variable immunodeficiency.
Topics: Adult; Aged; Alanine; Antibody Affinity; B-Lymphocyte Subsets; Clone Cells; Codon; Common Variable Immunodeficiency; Consensus Sequence; DNA Mutational Analysis; DNA-Binding Proteins; Genes, Immunoglobulin; Humans; Immunoglobulin Constant Regions; Immunoglobulin G; Immunoglobulin Heavy Chains; Immunoglobulin Variable Region; Immunologic Memory; Middle Aged; Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-6; Serine; Transcription Factors; Transcription, Genetic | 2000 |
Association between mutations of the follicle-stimulating-hormone receptor and repeated twinning.
Topics: Adenine; Adult; Alanine; Asparagine; Codon; Exons; Female; Genetic Linkage; Guanine; Humans; Phenotype; Point Mutation; Receptors, FSH; Serine; Threonine; Twins, Dizygotic | 2000 |
Phosphorylation of serine 51 in initiation factor 2 alpha (eIF2 alpha) promotes complex formation between eIF2 alpha(P) and eIF2B and causes inhibition in the guanine nucleotide exchange activity of eIF2B.
Topics: Alanine; Animals; Aspartic Acid; Baculoviridae; Cell-Free System; Eukaryotic Initiation Factor-2; Eukaryotic Initiation Factor-2B; Guanine Nucleotide Exchange Factors; Hemin; Humans; Male; Nucleopolyhedroviruses; Phosphorylation; Poly I-C; Rabbits; Recombinant Proteins; Reticulocytes; Serine; Spodoptera | 2000 |
Reactivity of manganese peroxidase: site-directed mutagenesis of residues in proximity to the porphyrin ring.
Topics: Alanine; Binding Sites; DNA, Complementary; Dose-Response Relationship, Drug; Escherichia coli; Hydrogen Peroxide; Kinetics; Leucine; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Peroxidases; Phenylalanine; Porphyrins; Protein Folding; Recombinant Proteins; Serine; Thermodynamics | 2000 |
Contribution of R domain phosphoserines to the function of CFTR studied in Fischer rat thyroid epithelia.
Topics: Alanine; Amino Acid Substitution; Animals; Cells, Cultured; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Membrane Potentials; Mutagenesis, Site-Directed; Phosphoserine; Rats; Rats, Inbred F344; Recombinant Proteins; Serine; Thyroid Gland; Transfection | 2000 |
Serine and alanine mutagenesis of the nine native cysteine residues of the human A(1) adenosine receptor.
Topics: Alanine; Amino Acid Sequence; Cells, Cultured; Cysteine; Humans; Molecular Sequence Data; Mutagenesis; Protein Conformation; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptors, Purinergic P1; Serine; Transfection; Tritium; Xanthines | 2000 |
Investigation of iodine-123-labelled amino acid derivatives for imaging cerebral gliomas: uptake in human glioma cells and evaluation in stereotactically implanted C6 glioma rats.
Topics: Alanine; Amino Acids; Amino Acids, Cyclic; Animals; beta-Alanine; Binding, Competitive; Blood-Brain Barrier; Brain Neoplasms; Cysteine; Glioblastoma; Humans; Iodine Radioisotopes; Isoquinolines; Male; Methyltyrosines; Neoplasm Transplantation; Phenylalanine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Serine; Tetrahydroisoquinolines; Tomography, Emission-Computed, Single-Photon; Tumor Cells, Cultured | 2000 |
The basis of prostaglandin synthesis in coral: molecular cloning and expression of a cyclooxygenase from the Arctic soft coral Gersemia fruticosa.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Blotting, Northern; Chromatography, Thin Layer; Cloning, Molecular; Cnidaria; COS Cells; Cyclooxygenase 1; Cyclooxygenase 2; DNA, Complementary; HeLa Cells; Histidine; Humans; Isoenzymes; Isoleucine; Membrane Proteins; Microscopy, Fluorescence; Models, Genetic; Molecular Sequence Data; Phylogeny; Plasmids; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Binding; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serine; Tyrosine | 2001 |
Reviving a dead enzyme: cytosine deaminations promoted by an inactive DNA methyltransferase and an S-adenosylmethionine analogue.
Topics: Adenosine; Alanine; Cysteine; Cytosine; Deamination; DNA (Cytosine-5-)-Methyltransferases; DNA-Cytosine Methylases; Enzyme Inhibitors; Escherichia coli; Mutagenesis, Site-Directed; S-Adenosylmethionine; Serine; Uracil | 2000 |
A model for the complex between the hypoxia-inducible factor-1 (HIF-1) and its consensus DNA sequence.
Topics: Alanine; Amino Acid Sequence; Animals; Crystallography; Dimerization; DNA-Binding Proteins; Erythropoietin; Histidine; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Lysine; Models, Molecular; Molecular Sequence Data; Monte Carlo Method; Nuclear Proteins; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Analysis, DNA; Serine; Software; Transcription Factors | 2000 |
Opioid pseudopeptides containing heteroaromatic or heteroaliphatic nuclei.
Topics: Alanine; Benzimidazoles; Binding Sites; Carbolines; Carboxylic Acids; Dipeptides; Isoquinolines; Kinetics; Ligands; Peptides; Proline; Propionates; Protein Conformation; Receptors, Opioid, delta; Receptors, Opioid, mu; Serine; Tetrahydroisoquinolines; Tyrosine | 2000 |
Protein kinase C-related kinase 2 phosphorylates the protein synthesis initiation factor eIF4E in starfish oocytes.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Biomarkers, Tumor; Eukaryotic Initiation Factor-4E; Female; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Peptide Initiation Factors; Peptide Mapping; Phosphopeptides; Phosphorylation; Protein Kinase C; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Starfish | 2000 |
A serine/alanine polymorphism in the nucleotide-binding fold-2 of the sulphonylurea receptor-1 (S1369A) is associated with enhanced glucose-induced insulin secretion during pregnancy.
Topics: Alanine; ATP-Binding Cassette Transporters; Binding Sites; Blood Glucose; C-Peptide; Codon; Diabetes, Gestational; Exons; Female; Genetic Variation; Glucose; Humans; Insulin; Insulin Secretion; Polymorphism, Genetic; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pregnancy; Receptors, Drug; Serine; Sulfonylurea Receptors | 2000 |
Amino acid residues conferring herbicide tolerance in tobacco acetolactate synthase.
Topics: Acetolactate Synthase; Alanine; Amino Acid Substitution; Drug Tolerance; Enzyme Induction; Herbicides; Imidazoles; Kinetics; Mutagenesis, Site-Directed; Nicotiana; Plants, Toxic; Proline; Pyrimidines; Recombinant Proteins; Serine; Structure-Activity Relationship; Sulfonylurea Compounds; Triazoles | 2000 |
Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69.
Topics: Alanine; Alleles; Bacteriophages; Base Sequence; Cell Division; Chromatography, Gel; Cloning, Molecular; DNA Replication; DNA-Directed DNA Polymerase; Escherichia coli; Genetic Complementation Test; Kinetics; Molecular Sequence Data; Mutagenesis; Mutation; Plasmids; Sequence Homology, Nucleic Acid; Serine; Threonine; Thymidine; Time Factors; Viral Proteins | 2001 |
Alternative O-glycosylation/O-phosphorylation of serine-16 in murine estrogen receptor beta: post-translational regulation of turnover and transactivation activity.
Topics: Acetylglucosamine; Alanine; Amino Acids; Animals; Binding Sites; Cell Line; Cell Nucleus; COS Cells; Cytoplasm; Estrogen Receptor beta; Glycosylation; Green Fluorescent Proteins; Luciferases; Luminescent Proteins; Mice; Microscopy, Fluorescence; Mutation; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Processing, Post-Translational; Receptors, Estrogen; Recombinant Fusion Proteins; Serine; Subcellular Fractions; Time Factors; Transcriptional Activation; Transfection | 2001 |
Ischemic dysfunction in transgenic mice expressing troponin I lacking protein kinase C phosphorylation sites.
Topics: Alanine; Animals; Binding Sites; Calcium; Feedback; Female; Homeostasis; In Vitro Techniques; Mice; Mice, Transgenic; Mutagenesis; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Organ Size; Oxygen Consumption; Phosphorylation; Protein Kinase C; Protein Structure, Tertiary; Serine; Troponin I; Ventricular Pressure | 2001 |
Electrogenic Na(+)-dependent L-alanine transport in the lizard duodenum. Involvement of systems A and ASC.
Topics: Alanine; Animals; beta-Alanine; Biological Transport; Carrier Proteins; Cysteine; Duodenum; Electric Conductivity; Epithelium; Intestinal Mucosa; Kinetics; Lizards; Membrane Potentials; Serine; Sodium | 2001 |
The role of a proline-induced broken-helix motif in alpha-helix 2 of Bacillus thuringiensis delta-endotoxins.
Topics: Alanine; Amino Acid Motifs; Animals; Bacillus thuringiensis; Bacillus thuringiensis Toxins; Bacterial Proteins; Bacterial Toxins; Cell Membrane; Chromatography, High Pressure Liquid; Electrophysiology; Endotoxins; Glycine; Hemolysin Proteins; Manduca; Microvilli; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Proline; Protein Structure, Secondary; Serine; Temperature; Time Factors | 2001 |
Synthesis of 2-amino-3-fluoroacrylic acid containing peptides.
Topics: Acrylates; Alanine; Dipeptides; Fluorine; Molecular Structure; Serine | 2001 |
Changing serine-485 to alanine in the opossum parathyroid hormone (PTH)/PTH-related peptide receptor enhances PTH stimulation of phospholipase C in a stably transfected human kidney cell line: a useful model for PTH-analog screening?
Topics: Alanine; Amino Acid Substitution; Animals; Binding, Competitive; Cell Line; Cyclic AMP; Humans; Inositol 1,4,5-Trisphosphate; Iodine Radioisotopes; Kidney; Mutagenesis, Site-Directed; Opossums; Parathyroid Hormone; Peptide Fragments; Protein Structure, Tertiary; Radioligand Assay; Receptors, Parathyroid Hormone; Serine; Signal Transduction; Transfection; Type C Phospholipases | 2001 |
Kinetic characterization of the double mutant R148A/E182S of glycogen phosphorylase kinase catalytic subunit: the role of the activation loop.
Topics: Alanine; Animals; Arginine; Catalysis; Enzyme Activation; Glutamic Acid; Kinetics; Models, Molecular; Mutation; Phosphorylase Kinase; Phosphorylation; Protein Conformation; Rabbits; Serine; Substrate Specificity | 2000 |
A helical turn motif in Mss4 is a critical determinant of Rab binding and nucleotide release.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Conserved Sequence; Evolution, Molecular; Guanine Nucleotide Exchange Factors; Guanosine Diphosphate; Helix-Turn-Helix Motifs; Kinetics; Mice; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Structure, Tertiary; Proteins; rab GTP-Binding Proteins; Rats; Sequence Homology, Amino Acid; Serine | 2001 |
Signal transduction by the CEACAM1 tumor suppressor. Phosphorylation of serine 503 is required for growth-inhibitory activity.
Topics: Alanine; Antigens, CD; Antigens, Differentiation; Aspartic Acid; Cell Adhesion Molecules; Genes, Tumor Suppressor; Mutagenesis, Site-Directed; Phosphorylation; Serine; Signal Transduction | 2001 |
Phosphorylation of Ser363, Thr370, and Ser375 residues within the carboxyl tail differentially regulates mu-opioid receptor internalization.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Diprenorphine; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphates; Phosphorylation; Phosphoserine; Phosphothreonine; Rats; Receptors, Opioid, mu; Recombinant Proteins; Serine; Threonine; Transfection | 2001 |
Identification of catalytically important residues in the active site of Escherichia coli transaldolase.
Topics: Alanine; Binding Sites; Catalysis; Crystallography, X-Ray; Escherichia coli; Fructose-Bisphosphate Aldolase; Kinetics; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Plasmids; Protons; Serine; Sugar Phosphates; Transaldolase | 2001 |
Inactivation of pyruvate formate-lyase by dioxygen: defining the mechanistic interplay of glycine 734 and cysteine 419 by rapid freeze-quench EPR.
Topics: Acetylation; Acetyltransferases; Alanine; Cysteine; Electron Spin Resonance Spectroscopy; Enzyme Activation; Escherichia coli; Free Radicals; Freezing; Glycine; Mutagenesis, Site-Directed; Oxygen; Peroxides; Serine | 2001 |
Phosphate-binding loop and Rab GTPase function: mutations at Ser29 and Ala30 of Rab5 lead to loss-of-function as well as gain-of-function phenotype.
Topics: Alanine; Animals; Cell Size; Cells, Cultured; Cricetinae; Endocytosis; GTP Phosphohydrolases; Mutation; Phenotype; Phosphates; rab5 GTP-Binding Proteins; Serine; Structure-Activity Relationship | 2001 |
Yersiniabactin synthetase: probing the recognition of carrier protein domains by the catalytic heterocyclization domains, Cy1 and Cy2, in the chain-initiating HWMP2 subunit.
Topics: Acyl Carrier Protein; Alanine; Amino Acid Isomerases; Amino Acid Substitution; Bacterial Outer Membrane Proteins; Bacterial Proteins; Catalytic Domain; Coenzyme A Ligases; Enzyme Activation; Iron-Binding Proteins; Molecular Weight; Peptide Chain Initiation, Translational; Peptide Synthases; Periplasmic Binding Proteins; Phenols; Protein Structure, Tertiary; Serine; Siderophores; Substrate Specificity; Thiazoles; Yersinia pestis | 2001 |
Consequences of a modified putative substrate-activation site on catalysis by yeast pyruvate decarboxylase.
Topics: Alanine; Catalysis; Cysteine; Deuterium Oxide; Enzyme Activation; Hydrogen; Kinetics; Models, Chemical; Pyruvate Decarboxylase; Recombinant Proteins; Saccharomyces cerevisiae; Serine; Solvents; Substrate Specificity; Thiamine Pyrophosphate; Thiazoles | 2001 |
Developmental and cell-cycle regulation of Caenorhabditis elegans HCF phosphorylation.
Topics: Alanine; Amino Acid Sequence; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Cycle; Cell Line; COS Cells; Cricetinae; Herpes Simplex Virus Protein Vmw65; Host Cell Factor C1; Humans; Larva; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoprotein Phosphatases; Phosphorylation; Proteins; Serine; Transcription Factors; Transfection | 2001 |
The chaperone protein 14-3-3eta interacts with the nicotinic acetylcholine receptor alpha 4 subunit. Evidence for a dynamic role in subunit stabilization.
Topics: 14-3-3 Proteins; Acetylcholine; Alanine; Animals; Brain; Colforsin; Cyclic AMP; Cytoplasm; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Enzyme-Linked Immunosorbent Assay; Immunoblotting; Immunoglobulin G; Immunohistochemistry; Microscopy, Confocal; Oocytes; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, Nicotinic; Recombinant Proteins; Serine; Transfection; Two-Hybrid System Techniques; Tyrosine 3-Monooxygenase; Xenopus | 2001 |
Electrically induced release of labelled taurine, alpha- and beta-alanine, glycine, glutamate and other amino acids from rat neocortical slices in vitro.
Topics: Alanine; Animals; Aspartic Acid; Carnosine; Electric Stimulation; Glutamic Acid; Glycine; Histidine; Neocortex; Neurons; Organ Culture Techniques; Rats; Serine; Taurine; Tritium | 1976 |
High-level bacterial expression and 15N-alanine-labeling of bovine trypsin. Application to the study of trypsin-inhibitor complexes and trypsinogen activation by NMR spectroscopy.
Topics: Alanine; Animals; Aprotinin; Aspartic Acid; Cattle; Enzyme Activation; Escherichia coli; Macromolecular Substances; Mutagenesis, Site-Directed; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Folding; Protons; Serine; Trypsin; Trypsin Inhibitor, Kunitz Soybean; Trypsin Inhibitors; Trypsinogen | 2001 |
Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease.
Topics: Alanine; Binding Sites; Catalytic Domain; Conserved Sequence; Crystallization; Crystallography, X-Ray; Cytomegalovirus; Dimerization; Glutamic Acid; Glutamine; Histidine; Humans; Kinetics; Mutagenesis, Site-Directed; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Serine; Serine Endopeptidases; Solvents | 2001 |
Acid-base catalysis by UDP-galactose 4-epimerase: correlations of kinetically measured acid dissociation constants with thermodynamic values for tyrosine 149.
Topics: Alanine; Catalysis; Deuterium; Electron Transport; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Protons; Serine; Spectrometry, Fluorescence; Temperature; Thermodynamics; Tyrosine; UDPglucose 4-Epimerase | 2001 |
Loss of clumping factor B fibrinogen binding activity by Staphylococcus aureus involves cessation of transcription, shedding and cleavage by metalloprotease.
Topics: Adhesins, Bacterial; Alanine; beta-Galactosidase; Binding Sites; Blotting, Southern; Blotting, Western; Coagulase; Dose-Response Relationship, Drug; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Genes, Reporter; Genotype; Leucine; Metalloendopeptidases; Mutagenesis, Site-Directed; Mutation; Phenanthrolines; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Staphylococcus aureus; Time Factors; Transcription, Genetic; Valine | 2001 |
Engineering a functional blue-wavelength-shifted rhodopsin mutant.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Cattle; COS Cells; Glutamic Acid; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Photochemistry; Retinaldehyde; Rhodopsin; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thermodynamics; Threonine; Transducin | 2001 |
Role of phylogenetically conserved amino acids in folding of Na,K-ATPase.
Topics: Alanine; Amino Acid Substitution; Amino Acids; Animals; Asparagine; Cell Membrane; Conserved Sequence; Endoplasmic Reticulum; Enzyme Activation; Gene Expression Regulation, Fungal; Lysine; Mutagenesis, Site-Directed; Peptide Fragments; Phylogeny; Protein Folding; Recombinant Proteins; RNA, Messenger; Saccharomyces cerevisiae; Serine; Sodium-Potassium-Exchanging ATPase; Swine; Temperature; Threonine | 2001 |
Interaction between DNA gyrase and quinolones: effects of alanine mutations at GyrA subunit residues Ser(83) and Asp(87).
Topics: 4-Quinolones; Alanine; Amino Acid Substitution; Anti-Infective Agents; Aspartic Acid; Binding, Competitive; Calcium; DNA Topoisomerases, Type II; DNA, Bacterial; DNA, Superhelical; Drug Resistance, Microbial; Escherichia coli; Humans; Models, Molecular; Mutation; Nucleic Acid Conformation; Serine | 2001 |
Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity.
Topics: Alanine; Allosteric Regulation; Aniline Compounds; Aspartic Acid; Benzimidazoles; beta-Alanine; Catalysis; Deuterium; Enzyme Activation; Hydroxylamines; Indoles; Kinetics; Multienzyme Complexes; Mutagenesis, Site-Directed; Pyruvic Acid; Salmonella typhimurium; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity; Titrimetry; Tryptophan Synthase | 2001 |
cis-Inhibition of proteasomal degradation by viral repeats: impact of length and amino acid composition.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Cysteine Endopeptidases; DNA-Binding Proteins; Epstein-Barr Virus Nuclear Antigens; Female; Glycine; HeLa Cells; Humans; I-kappa B Proteins; Molecular Sequence Data; Molecular Weight; Multienzyme Complexes; NF-KappaB Inhibitor alpha; Proteasome Endopeptidase Complex; Protein Conformation; Protein Processing, Post-Translational; Repetitive Sequences, Amino Acid; Serine; Transfection; Tumor Necrosis Factor-alpha; Ubiquitins; Valine; Viral Proteins | 2001 |
Determination of free D-aspartic acid, D-serine and D-alanine in the brain of mutant mice lacking D-amino acid oxidase activity.
Topics: Alanine; Animals; Aspartic Acid; Brain Chemistry; Chromatography, High Pressure Liquid; D-Amino-Acid Oxidase; Male; Mice; Mice, Mutant Strains; Serine | 2001 |
Characterization of Na+-coupled glutamate/aspartate transport by a rat brain astrocyte line expressing GLAST and EAAC1.
Topics: Alanine; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Blotting, Western; Carrier Proteins; Cell Line; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 3; Ganglionic Stimulants; Genistein; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Ionophores; Kainic Acid; Protein Isoforms; Protein-Tyrosine Kinases; Quaternary Ammonium Compounds; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Sodium; Symporters; Telencephalon; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
The YXXQ motif in gp 130 is crucial for STAT3 phosphorylation at Ser727 through an H7-sensitive kinase pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Antigens, CD; Binding Sites; Carcinoma, Hepatocellular; Cell Line; Cytokine Receptor gp130; DNA Primers; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; Granulocyte Colony-Stimulating Factor; Humans; Interferon-gamma; Interleukin-6; Liver Neoplasms; Membrane Glycoproteins; Mice; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinases; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Signal Transduction; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2001 |
Studies on analogs of a peptide derived from alpha-fetoprotein having antigrowth properties.
Topics: Alanine; alpha-Fetoproteins; Animals; Antineoplastic Agents; Chromatography, Gel; Cysteine; Dose-Response Relationship, Drug; Epitopes; Estrogens; Female; Glycine; Humans; Hydrogen-Ion Concentration; Mice; Peptides; Protein Structure, Secondary; Serine; Time Factors; Uterus | 2001 |
Mutagenesis of beta-tubulin cysteine residues in Saccharomyces cerevisiae: mutation of cysteine 354 results in cold-stable microtubules.
Topics: Alanine; Benomyl; Cold Temperature; Cysteine; Fungal Proteins; Fungicides, Industrial; Microtubules; Mutagenesis, Site-Directed; Protein Structure, Secondary; Saccharomyces cerevisiae; Serine; Tubulin | 2001 |
Sites on FIP-3 (NEMO/IKKgamma) essential for its phosphorylation and NF-kappaB modulating activity.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cell Line; Humans; I-kappa B Kinase; Isoenzymes; Leucine Zippers; Molecular Sequence Data; Mutagenesis, Site-Directed; NF-kappa B; Phosphorylation; Point Mutation; Protein Kinase C; Protein Kinase C-alpha; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Transfection | 2001 |
MALDI-PSD-MS analysis of the phosphorylation sites of caseinomacropeptide.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Binding Sites; Caseins; Chromatography, High Pressure Liquid; Chymosin; Glycosylation; Molecular Sequence Data; Peptide Fragments; Peptides; Phosphorylation; Phosphoserine; Protein Processing, Post-Translational; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors | 2001 |
Synergistic interactions of multiple mutations on catalysis during the hydroxylation reaction of p-hydroxybenzoate hydroxylase: studies of the Lys297Met, Asn300Asp, and Tyr385Phe mutants reconstituted with 8-Cl-flavin.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Alanine; Amino Acid Substitution; Anaerobiosis; Asparagine; Aspartic Acid; Catalysis; Flavin-Adenine Dinucleotide; Hydroxylation; Lysine; Methionine; Mutagenesis, Site-Directed; Oxidation-Reduction; Parabens; Phenylalanine; Riboflavin; Serine; Spectrophotometry; Substrate Specificity; Tyrosine | 2001 |
Membrane interactions of mutated forms of the influenza fusion peptide.
Topics: Alanine; Amino Acid Sequence; Deuterium; Glutamic Acid; Glycine; Hemagglutinin Glycoproteins, Influenza Virus; Kinetics; Lipid Bilayers; Membrane Fusion; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Phosphorus Isotopes; Protein Conformation; Protein Structure, Secondary; Serine; Spectroscopy, Fourier Transform Infrared; Valine; Viral Fusion Proteins | 2001 |
Molecular and cellular physiology of the dissociation of atrial natriuretic peptide from guanylyl cyclase a receptors.
Topics: Alanine; Animals; Atrial Natriuretic Factor; Binding, Competitive; Catalysis; Cell Membrane; Cells, Cultured; CHO Cells; Cricetinae; Cyclic GMP; Cytoplasm; Gene Deletion; Glycine; Guanylate Cyclase; Kinetics; Ligands; Mutagenesis, Site-Directed; Mutation; Point Mutation; Protein Binding; Protein Structure, Tertiary; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Serine; Temperature; Time Factors; Transfection | 2001 |
Identification of potential substrate-binding sites in yeast and human acyl-CoA sterol acyltransferases by mutagenesis of conserved sequences.
Topics: Acyltransferases; Alanine; Amino Acid Sequence; Animals; Binding Sites; Conserved Sequence; Esterification; Gene Deletion; Gene Expression; Humans; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation, Missense; Promoter Regions, Genetic; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Sterol O-Acyltransferase; Structure-Activity Relationship; Transfection; Tryptophan; Tyrosine | 2001 |
Activation of protein kinase D by signaling through Rho and the alpha subunit of the heterotrimeric G protein G13.
Topics: A Kinase Anchor Proteins; Adaptor Proteins, Signal Transducing; Alanine; Aluminum Compounds; Animals; COS Cells; DNA, Complementary; Enzyme Activation; Fluorides; Genes, Dominant; Green Fluorescent Proteins; GTP-Binding Protein alpha Subunits, G12-G13; Heterotrimeric GTP-Binding Proteins; Indoles; Luminescent Proteins; Minor Histocompatibility Antigens; Models, Biological; Mutation; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Proto-Oncogene Proteins; Receptors, Bombesin; Recombinant Fusion Proteins; rho GTP-Binding Proteins; Serine; Signal Transduction; Transfection | 2001 |
Characterization of loops of the yeast mitochondrial ADP/ATP carrier facing the cytosol by site-directed mutagenesis.
Topics: Adenosine Diphosphate; Alanine; Anti-Bacterial Agents; Blotting, Western; Bongkrekic Acid; Cell Division; Cysteine; Cytosol; DNA; DNA Primers; Electrophoresis, Polyacrylamide Gel; Eosine Yellowish-(YS); Fluorescent Dyes; Mitochondria; Mitochondrial ADP, ATP Translocases; Models, Biological; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Protein Transport; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine | 2001 |
Alanine synthesis from glyceraldehyde and ammonium ion in aqueous solution.
Topics: Acetylcysteine; Alanine; Evolution, Chemical; Evolution, Molecular; Formates; Glyceraldehyde; Glycine; Glycolates; Lactic Acid; Quaternary Ammonium Compounds; Serine; Sulfhydryl Compounds | 1985 |
Determination of free intracellular amino acids in single mouse peritoneal macrophages after naphthalene-2,3-dicarboxaldehyde derivatization by capillary zone electrophoresis with electrochemical detection.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cell Extracts; Electrochemistry; Electrophoresis, Capillary; Glutamic Acid; Glycine; Intracellular Fluid; Macrophages, Peritoneal; Mice; Naphthalenes; Serine; Taurine | 2001 |
Uptake of D-serine by synaptosomal P2 fraction isolated from rat brain.
Topics: Alanine; Animals; Binding, Competitive; Brain; Carrier Proteins; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Isomerism; Male; Neurons; Neurotransmitter Agents; Pharmacokinetics; Rats; Rats, Wistar; Serine; Synaptosomes; Temperature; Tritium | 2001 |
ATP synthase F(1) sector rotation. Defective torque generation in the beta subunit Ser-174 to Phe mutant and its suppression by second mutations.
Topics: Actins; Adenosine Triphosphate; Alanine; Escherichia coli; Glycine; Hydrolysis; Isoleucine; Models, Molecular; Mutation; Phenylalanine; Protein Conformation; Protein Structure, Tertiary; Proton-Translocating ATPases; Serine; Time Factors | 2001 |
Amino acid metabolism of bovine blastocysts derived from parthenogenetically activated or in vitro fertilized oocytes.
Topics: Alanine; Amino Acids; Animals; Asparagine; Blastocyst; Cattle; Cryopreservation; Culture Techniques; Female; Fertilization in Vitro; Glutamic Acid; Glutamine; Glycine; Oocytes; Parthenogenesis; Serine | 1998 |
Structural basis for the substrate specificity of the feruloyl esterase domain of the cellulosomal xylanase Z from Clostridium thermocellum.
Topics: Alanine; Amino Acid Sequence; Carboxylic Ester Hydrolases; Catalytic Domain; Clostridium; Computer Simulation; Crystallization; Crystallography, X-Ray; Endo-1,4-beta Xylanases; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Structure, Tertiary; Serine; Substrate Specificity; Trisaccharides; Xylosidases | 2001 |
Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Casein Kinase II; Cell Division; Gene Deletion; Glutamic Acid; Histone Deacetylase 1; Histone Deacetylase 2; Histone Deacetylases; Humans; Jurkat Cells; Luciferases; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Repressor Proteins; Sequence Homology, Amino Acid; Serine; Transcription, Genetic; Transfection | 2001 |
Asymmetric synthesis of gamma-keto-delta-lactam derivatives: application to the synthesis of a conformationally constrained surrogate of Ala-Ser dipeptide.
Topics: Alanine; Dipeptides; Lactams; Nuclear Magnetic Resonance, Biomolecular; Piperidones; Protein Conformation; Serine; Stereoisomerism | 2001 |
Role of conservative residue Cys158 in the formation of an active photoprotein complex of obelin.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Apoproteins; Conserved Sequence; Cysteine; Kinetics; Luminescent Measurements; Luminescent Proteins; Recombinant Proteins; Serine | 2001 |
Importance of the conserved nucleotides around the tRNA-like structure of Escherichia coli transfer-messenger RNA for protein tagging.
Topics: Acylation; Alanine; Arginine; Bacterial Proteins; Base Sequence; Binding Sites; Blotting, Northern; Conserved Sequence; Escherichia coli; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Open Reading Frames; Peptide Elongation Factor Tu; Ribosomal Proteins; Ribosomes; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Serine; Threonine | 2001 |
Genetic analysis of the Epstein-Barr virus-coded leader protein EBNA-LP as a co-activator of EBNA2 function.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; B-Lymphocytes; Cell Line, Transformed; Epstein-Barr Virus Nuclear Antigens; Gene Deletion; Genes, Viral; Herpesvirus 4, Human; Humans; Molecular Sequence Data; Sequence Alignment; Serine; Viral Proteins | 2001 |
Mutational analysis of conserved glycines 42 and 256 in Cephalosporium acremonium isopenicillin N synthase.
Topics: Acremonium; Alanine; Amino Acid Sequence; DNA Mutational Analysis; Glycine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidoreductases; Sequence Alignment; Serine; Temperature | 2001 |
p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis.
Topics: Alanine; Animals; Antifungal Agents; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p27; Cytoplasm; Enzyme Activation; Estradiol; Estrogen Antagonists; Fatty Acids, Unsaturated; Fibroblasts; Immunoblotting; Microscopy, Fluorescence; Mutation; Phosphorylation; Protein Binding; Protein Transport; Rats; Serine; Tamoxifen; Time Factors; Transfection; Tumor Suppressor Proteins; Ubiquitin | 2001 |
Nuclear export of phosphorylated C/EBPbeta mediates the inhibition of albumin expression by TNF-alpha.
Topics: Active Transport, Cell Nucleus; Aged; Alanine; Animals; Antibiotics, Antineoplastic; Antioxidants; Cachexia; Case-Control Studies; CCAAT-Enhancer-Binding Protein-beta; Cell Nucleus; Cells, Cultured; CHO Cells; Cricetinae; Cytoplasm; Fatty Acids, Unsaturated; Hepatocytes; Humans; Immunoblotting; Immunohistochemistry; Lipopolysaccharides; Liver; Male; Mice; Middle Aged; Molsidomine; Mutation; Nitric Oxide Donors; Nitric Oxide Synthase; Oxidative Stress; Phosphorylation; Precipitin Tests; Promoter Regions, Genetic; Protein Structure, Tertiary; Serine; Serum Albumin; Time Factors; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha | 2001 |
Adjacent cysteine residues as a redox switch.
Topics: Alanine; Amino Acid Sequence; Catalysis; Cysteine; Disulfides; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Plasmids; Protein Conformation; Ribonuclease, Pancreatic; Sequence Homology, Amino Acid; Serine | 2001 |
Modulation of hormone-sensitive lipase and protein kinase A-mediated lipolysis by perilipin A in an adenoviral reconstituted system.
Topics: 3T3 Cells; Adenoviridae; Alanine; Animals; Bacterial Outer Membrane Proteins; Blotting, Western; Carrier Proteins; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Hydrolysis; Lipid Metabolism; Mice; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Perilipin-1; Phosphoproteins; Phosphorylation; Plasmids; Protein Binding; Protein Conformation; Serine; Sterol Esterase; Triglycerides | 2002 |
Differing substrate specificities of members of the DYRK family of arginine-directed protein kinases.
Topics: Alanine; Animals; Arginine; Dyrk Kinases; Eukaryotic Initiation Factor-2B; Peptides; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Serine; Substrate Specificity | 2002 |
A potent human immunodeficiency virus type 1 protease inhibitor, UIC-94003 (TMC-126), and selection of a novel (A28S) mutation in the protease active site.
Topics: Alanine; Amino Acid Sequence; Catalytic Domain; Cell Line; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Laboratories; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Sulfonamides; Urethane | 2002 |
Structural features underlying the multisite phosphorylation of the A domain of the NF-AT4 transcription factor by protein kinase CK1.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Casein Kinases; Chromatography, High Pressure Liquid; Cytosol; DNA-Binding Proteins; Gene Deletion; Kinetics; Liver; Models, Biological; Molecular Sequence Data; NFATC Transcription Factors; Nuclear Proteins; Peptides; Phosphorylation; Protein Isoforms; Protein Kinases; Protein Structure, Tertiary; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; T-Lymphocytes; Time Factors; Transcription Factors; Zebrafish | 2002 |
A novel serine-rich motif in the intercellular adhesion molecule 3 is critical for its ezrin/radixin/moesin-directed subcellular targeting.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Antigens, CD; Antigens, Differentiation; Blood Proteins; Blotting, Western; CD4 Antigens; Cell Adhesion Molecules; Cell Communication; Cell Line; Cell Membrane; Cell Movement; Cytoplasm; Cytoskeletal Proteins; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Green Fluorescent Proteins; Humans; K562 Cells; Luminescent Proteins; Lymphocytes; Membrane Proteins; Mice; Microfilament Proteins; Microscopy, Fluorescence; Microscopy, Video; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Transfection | 2002 |
Essential hydrophilic carboxyl-terminal regions including cysteine residues of the yeast stretch-activated calcium-permeable channel Mid1.
Topics: Alanine; Alleles; Asparagine; Binding Sites; Calcium; Calcium Channels; Codon; Codon, Nonsense; Cysteine; Fungal Proteins; Hydroxylamine; Immunoblotting; Membrane Glycoproteins; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine; Time Factors; Tryptophan; Two-Hybrid System Techniques | 2002 |
Hydration effects of heparin on antithrombin probed by osmotic stress.
Topics: Alanine; Antithrombins; Asparagine; Binding Sites; Heparin; Isoleucine; Kinetics; Leucine; Models, Molecular; Osmotic Pressure; Protein Binding; Serine; Spectrometry, Fluorescence; Thermodynamics; Threonine; Time Factors; Tryptophan; Valine; Water; X-Rays | 2002 |
Importance of Na,K-ATPase residue alpha 1-Arg544 in the segment Arg544-Asp567 for high-affinity binding of ATP, ADP, or MgATP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Conserved Sequence; Cysteine; Glutamic Acid; Magnesium; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylation; Saccharomyces cerevisiae; Serine; Sodium-Potassium-Exchanging ATPase; Swine; Thermodynamics | 2002 |
Mutation at the CK2 phosphorylation site on Cdc28 affects kinase activity and cell size in Saccharomyces cerevisiae.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Casein Kinase II; Catalytic Domain; CDC28 Protein Kinase, S cerevisiae; Cell Cycle; Cyclin A; G1 Phase; Genotype; Histones; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Serine | 2001 |
Modulation of cyanoalanine synthase and O-acetylserine (thiol) lyases A and B activity by beta-substituted alanyl and anion inhibitors.
Topics: Alanine; Allosteric Regulation; Allosteric Site; Anions; Carbon-Oxygen Lyases; Cysteine; Cysteine Synthase; Dimerization; Homocysteine; Hydrogen Bonding; Intracellular Membranes; Isoenzymes; Kinetics; Lyases; Mitochondria; Models, Biological; Multienzyme Complexes; Potassium Cyanide; Saccharomyces cerevisiae Proteins; Serine; Spinacia oleracea | 2002 |
Protein kinase D is a downstream target of protein kinase Ctheta.
Topics: Alanine; Amino Acid Substitution; Animals; Catalytic Domain; COS Cells; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Jurkat Cells; Maleimides; Mutation; Phorbol 12,13-Dibutyrate; Precipitin Tests; Protein Kinase C; Protein Kinase C-theta; Serine; Signal Transduction; T-Lymphocytes; Transfection | 2002 |
Substitution of Gly-548 to Ala in the substrate binding pocket of prothrombin Perijá leads to the loss of thrombin proteolytic activity.
Topics: Alanine; Amino Acid Substitution; Antithrombin III; Arginine; Binding Sites; Catalytic Domain; Codon; DNA Mutational Analysis; Enzyme Activation; Enzyme Inhibitors; Exons; Factor V; Factor Xa; Glycine; Humans; Models, Molecular; Pipecolic Acids; Polymorphism, Single-Stranded Conformational; Protein Conformation; Prothrombin; Serine; Structure-Activity Relationship; Sulfonamides; Thrombin | 2002 |
Single replacement constructs of all hydroxyl, basic, and acidic amino acids identify new function and structure-sensitive regions of the mitochondrial phosphate transport protein.
Topics: Alanine; Amino Acid Motifs; Amino Acid Substitution; Biological Transport; Inclusion Bodies; Liposomes; Membrane Proteins; Mitochondrial Proteins; Mutation; Phosphate Transport Proteins; Protein Structure, Secondary; Saccharomyces cerevisiae; Serine | 2002 |
Crystal structure of the human estrogen sulfotransferase-PAPS complex: evidence for catalytic role of Ser137 in the sulfuryl transfer reaction.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Estradiol; Lysine; Macromolecular Substances; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Phosphoadenosine Phosphosulfate; Protein Binding; Protein Conformation; Serine; Sulfates; Sulfotransferases | 2002 |
Phosphorylation-dependent cellular localization and thermoprotective role of heat shock protein 25 in hippocampal progenitor cells.
Topics: Active Transport, Cell Nucleus; Alanine; Animals; Apoptosis; Aspartic Acid; Blotting, Northern; Blotting, Western; Cell Line; Cell Nucleus; Cytochalasin D; Cytoplasm; DNA Fragmentation; Enzyme Inhibitors; Flavonoids; Flow Cytometry; Heat-Shock Proteins; Hippocampus; Hot Temperature; HSP27 Heat-Shock Proteins; Imidazoles; Immunohistochemistry; Mitogen-Activated Protein Kinases; Models, Genetic; Mutation; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Precipitin Tests; Propidium; Pyridines; Rats; Serine; Signal Transduction; Stem Cells; Temperature; Time Factors; Transfection | 2002 |
Zn(2+) binding properties of single-point mutants of the C-terminal zinc finger of the HIV-1 nucleocapsid protein: evidence of a critical role of cysteine 49 in Zn(2+) dissociation.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Capsid; Capsid Proteins; Cobalt; Cysteine; gag Gene Products, Human Immunodeficiency Virus; Gene Products, gag; Histidine; HIV-1; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Sequence Data; Point Mutation; Protein Binding; Serine; Spectrophotometry; Viral Proteins; Zinc; Zinc Fingers | 2002 |
Racemic amino acids from the ultraviolet photolysis of interstellar ice analogues.
Topics: Alanine; Amino Acids; Glycine; Ice; Meteoroids; Molecular Conformation; Photochemistry; Serine; Ultraviolet Rays | 2002 |
Selective intranuclear redistribution of PPAR isoforms by RXR alpha.
Topics: Active Transport, Cell Nucleus; Alanine; Amino Acid Substitution; Animals; Blotting, Western; Cell Nucleus; Dimerization; Green Fluorescent Proteins; Histone Acetyltransferases; Humans; Ligands; Luminescent Proteins; Mice; Microscopy, Fluorescence; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Nuclear Receptor Coactivator 1; Phosphorylation; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Repressor Proteins; Retinoid X Receptors; Serine; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
Effect of three n-acetylamino acids on N-(3,5-dichlorophenyl)succinimide (NDPS) and ndps metabolite nephrotoxicity in Fischer 344 rats.
Topics: Acetylcysteine; Alanine; Amino Acids; Animals; Fungicides, Industrial; Injections, Intraperitoneal; Kidney; Kidney Diseases; Kidney Function Tests; Liver; Male; Rats; Rats, Inbred F344; Serine; Serotonin; Succinates; Succinimides | 2002 |
The Golgi localization of phosphatidylinositol transfer protein beta requires the protein kinase C-dependent phosphorylation of serine 262 and is essential for maintaining plasma membrane sphingomyelin levels.
Topics: 3T3 Cells; Alanine; Animals; Blotting, Western; Carrier Proteins; Cell Membrane; Enzyme Inhibitors; Fibroblasts; Golgi Apparatus; Indoles; Maleimides; Membrane Proteins; Mice; Mutagenesis, Site-Directed; Peptides; Phospholipid Transfer Proteins; Phosphorylation; Protein Binding; Protein Kinase C; Rats; Serine; Sphingomyelins; Time Factors; Transfection | 2002 |
RACK1 is an insulin-like growth factor 1 (IGF-1) receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death.
Topics: Alanine; Animals; Blotting, Western; Cell Death; Cell Division; Cell Survival; Cloning, Molecular; COS Cells; Enzyme Activation; Fibroblasts; GTP-Binding Proteins; Humans; Mutation; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptors for Activated C Kinase; Receptors, Cell Surface; Recombinant Proteins; Serine; Time Factors; Transfection; Tumor Cells, Cultured; Two-Hybrid System Techniques | 2002 |
Phosphorylation-dependent interaction of kinesin light chain 2 and the 14-3-3 protein.
Topics: 14-3-3 Proteins; Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Cell Line; Conserved Sequence; Humans; Isoenzymes; Kinesins; MAP Kinase Signaling System; Microtubule-Associated Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; PC12 Cells; Peptide Fragments; Phosphorylation; Phosphoserine; Rats; Serine; Tyrosine 3-Monooxygenase | 2002 |
The activity of leukocyte NADPH oxidase: regulation by p47PHOX cysteine and serine residues.
Topics: Alanine; Cell-Free System; Cysteine; Cytosol; Gene Expression Regulation, Enzymologic; Humans; Leukocytes; Lymphocytes; Mutation; NADPH Oxidases; Oxidation-Reduction; Phosphoproteins; Phosphorylation; Serine | 2002 |
Ras signaling enhances the activity of C/EBP alpha to induce granulocytic differentiation by phosphorylation of serine 248.
Topics: Acute Disease; Alanine; Amino Acid Substitution; CCAAT-Enhancer-Binding Protein-alpha; Cell Differentiation; Cell Line; Granulocytes; Humans; Leukemia, Myeloid; Phosphorylation; Point Mutation; Promoter Regions, Genetic; Protein Kinase C; ras Proteins; Receptors, Granulocyte Colony-Stimulating Factor; Serine; Signal Transduction; Transcriptional Activation | 2002 |
Release of excitatory amino acids in the penumbra of a focal cortical necrosis.
Topics: Alanine; Animals; Aspartic Acid; Cerebral Cortex; Excitatory Amino Acids; Glutamic Acid; Glycine; Male; Microdialysis; Necrosis; Rats; Serine | 2002 |
Mutagenesis and mechanism-based inhibition of Streptococcus pyogenes Glu-tRNAGln amidotransferase implicate a serine-based glutaminase site.
Topics: Alanine; Amides; Amino Acid Sequence; Aminoacyltransferases; Binding Sites; Binding, Competitive; Boronic Acids; Conserved Sequence; Glutaminase; Glutamine; Hydrolysis; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrogenous Group Transferases; Serine; Streptococcus pyogenes | 2002 |
Glucocorticoid receptor domain requirements for chromatin remodeling and transcriptional activation of the mouse mammary tumor virus promoter in different nucleoprotein contexts.
Topics: Alanine; Amino Acid Substitution; Animals; Base Sequence; Binding Sites; Chromatin; Cloning, Molecular; Dexamethasone; Mammary Tumor Virus, Mouse; Mice; Models, Molecular; Mutagenesis, Site-Directed; Nuclear Proteins; Nucleoproteins; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Protein Structure, Secondary; Receptors, Glucocorticoid; Receptors, Interferon; Recombinant Fusion Proteins; Serine; Templates, Genetic; Transfection; Tumor Cells, Cultured | 2002 |
A novel alanine-insensitive D-serine transporter in rat brain synaptosomal membranes.
Topics: Alanine; Amino Acid Transport Systems; Animals; Brain; Hippocampus; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synaptosomes; Time Factors | 2002 |
The synergistic anion-binding sites of human transferrin: chemical and physiological effects of site-directed mutagenesis.
Topics: Alanine; Anions; Arginine; Binding Sites; Carbonic Acid; Drug Synergism; Electron Spin Resonance Spectroscopy; Humans; Iron; K562 Cells; Kinetics; Mutagenesis, Site-Directed; Nitrilotriacetic Acid; Peptide Fragments; Recombinant Proteins; Serine; Spectrophotometry; Threonine; Transferrin | 2002 |
Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation.
Topics: 3T3 Cells; Alanine; Animals; Carrier Proteins; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Cyclin D1; Enzyme Inhibitors; Flavonoids; G1 Phase; Glutamic Acid; Glutamine; Glutathione Transferase; Intracellular Signaling Peptides and Proteins; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Peptide Mapping; Phosphorylation; Phosphoserine; Plasmids; Protein Structure, Tertiary; ras Proteins; Resting Phase, Cell Cycle; S Phase; Serine; Time Factors; Transfection | 2002 |
Lack of association between calcium-sensing receptor gene "A986S" polymorphism and bone mineral density in Hungarian postmenopausal women.
Topics: Aged; Alanine; Alleles; Amino Acid Substitution; Analysis of Variance; Bone Density; Calcium; Cohort Studies; Female; Femur; Genotype; Humans; Hungary; Lumbar Vertebrae; Middle Aged; Osteoporosis, Postmenopausal; Polymorphism, Genetic; Receptors, Calcium-Sensing; Receptors, Cell Surface; Serine | 2002 |
Creatinine inhibits D-amino acid oxidase.
Topics: Alanine; Alanine Transaminase; Creatinine; D-Amino-Acid Oxidase; Enzyme Activation; Flavin-Adenine Dinucleotide; Humans; In Vitro Techniques; Serine; Uremia | 2002 |
Functional and structural changes due to a serine to alanine mutation in the active-site flap of enolase.
Topics: Alanine; Amino Acid Substitution; Catalytic Domain; Crystallography, X-Ray; Deuterium; Enzyme Activation; Escherichia coli; Kinetics; Metals; Models, Molecular; Mutagenesis, Site-Directed; Phosphopyruvate Hydratase; Protein Conformation; Protein Folding; Recombinant Proteins; Saccharomyces cerevisiae; Serine; Static Electricity; Thermodynamics | 2002 |
Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation.
Topics: Alanine; Cell-Free System; Cytosol; Enzyme Activation; Enzyme Inhibitors; Humans; Isoenzymes; Membrane Transport Proteins; Mutagenesis, Site-Directed; NADPH Dehydrogenase; NADPH Oxidases; Peptide Mapping; Phosphopeptides; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-delta; Recombinant Fusion Proteins; Serine | 2002 |
Negative feedback regulation of the tumor suppressor PTEN by phosphoinositide-induced serine phosphorylation.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cells, Cultured; Down-Regulation; Feedback; Half-Life; Humans; Jurkat Cells; Molecular Sequence Data; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphoric Monoester Hydrolases; Phosphorylation; PTEN Phosphohydrolase; Serine; T-Lymphocytes; Tumor Suppressor Proteins | 2002 |
Homonuclear zero-quantum recoupling in fast magic-angle spinning nuclear magnetic resonance.
Topics: Alanine; Carbon Isotopes; Glycine; Magnetic Resonance Spectroscopy; Mathematics; Serine; Tyrosine | 2002 |
Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway.
Topics: Alanine; Amino Acid Substitution; Antigens, Neoplasm; Base Sequence; Breast Neoplasms; Cell Line; DNA Primers; Female; Histidine Kinase; Humans; Kinetics; Monomeric GTP-Binding Proteins; Mutagenesis, Site-Directed; Neoplasm Metastasis; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Phosphorylation; Protein Kinases; ras Proteins; Recombinant Proteins; Serine; Substrate Specificity; Transcription Factors; Transfection; Tumor Cells, Cultured | 2002 |
Identification of two C-terminal amino acids, Ser(355) and Thr(357), required for short-term homologous desensitization of mu-opioid receptors.
Topics: Alanine; Amino Acid Substitution; Cells, Cultured; Humans; Phosphorylation; Protein Structure, Tertiary; Receptors, Opioid, mu; Serine; Threonine | 2002 |
Evidence of a critical architectural function for the RAG proteins in end processing, protection, and joining in V(D)J recombination.
Topics: Alanine; Amino Acid Substitution; Animals; Cell Line; Cysteine; DNA; DNA Nucleotidyltransferases; DNA-Binding Proteins; Gene Rearrangement, B-Lymphocyte; Genes, RAG-1; Glutamic Acid; Homeodomain Proteins; Humans; Macromolecular Substances; Mice; Mutagenesis, Site-Directed; Nuclear Proteins; Nucleic Acid Conformation; Phenotype; Protein Interaction Mapping; Recombinant Fusion Proteins; Recombination, Genetic; Regulatory Sequences, Nucleic Acid; Serine; Substrate Specificity; VDJ Recombinases | 2002 |
Signal-induced site specific phosphorylation targets Bcl2 to the proteasome pathway.
Topics: Alanine; Amino Acid Substitution; Apoptosis; Binding Sites; Cantharidin; Cysteine Endopeptidases; Enzyme Inhibitors; Humans; Multienzyme Complexes; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphoprotein Phosphatases; Phosphorylation; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-bcl-2; Serine; Signal Transduction; Substrate Specificity; Transfection; Tumor Cells, Cultured | 2002 |
Cerebrospinal fluid glutamine, tryptophan, and tryptophan metabolite concentrations in dogs with portosystemic shunts.
Topics: Alanine; Animals; Dietary Proteins; Dog Diseases; Dogs; Female; Glutamine; Hepatic Encephalopathy; Hydroxyindoleacetic Acid; Male; Portal System; Quinolinic Acid; Serine; Tryptophan | 2002 |
Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase.
Topics: Alanine; Binding Sites; Enzyme Inhibitors; Humans; Hydrolysis; Models, Molecular; Mutagenesis, Site-Directed; Phosphoric Monoester Hydrolases; Protein Conformation; Serine; Substrate Specificity | 2002 |
Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress.
Topics: Adenoviridae; Alanine; Amino Acid Sequence; Animals; Apoptosis; Binding Sites; Blotting, Western; Cell Line; Cell Survival; DNA, Complementary; Escherichia coli; Humans; Hydrogen Peroxide; Mice; Mitochondria; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Oxidative Stress; Oxygen; p38 Mitogen-Activated Protein Kinases; Phosphoric Monoester Hydrolases; Phosphorylation; Plasmids; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-bcl-2; Sequence Homology, Amino Acid; Serine; Threonine; Transfection | 2002 |
Induction of tumor-reactive CTL by C-side chain variants of the CTL epitope HER-2/neu protooncogene (369-377) selected by molecular modeling of the peptide: HLA-A2 complex.
Topics: Adjuvants, Immunologic; Alanine; Amino Acid Substitution; Antigen Presentation; Antigens, Neoplasm; Apoptosis; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Line; Cell Survival; Cytotoxicity, Immunologic; Epitopes, T-Lymphocyte; Genes, erbB-2; Glycine; HLA-A2 Antigen; Humans; Interferon-gamma; Lymphocyte Activation; Lysine; Models, Molecular; Peptide Fragments; Serine; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured | 2002 |
Assessment of enamelysin (MMP-20) selectivity to three peptide bonds on amelogenin sequence.
Topics: Alanine; Amelogenesis; Amelogenin; Amino Acid Sequence; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Dental Enamel; Dental Enamel Proteins; Hydrolysis; Leucine; Matrix Metalloproteinase 20; Matrix Metalloproteinases; Methionine; Peptide Mapping; Proline; Protein Folding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Proteins; Serine; Statistics as Topic; Substrate Specificity; Swine; Time Factors; Tooth Calcification; Tryptophan | 2002 |
Nuclear export of glucocorticoid receptor is enhanced by c-Jun N-terminal kinase-mediated phosphorylation.
Topics: Active Transport, Cell Nucleus; Alanine; Amino Acid Sequence; Animals; COS Cells; Dexamethasone; Enzyme Activation; Fatty Acids, Unsaturated; Green Fluorescent Proteins; HeLa Cells; Humans; JNK Mitogen-Activated Protein Kinases; Luminescent Proteins; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Mutation; Phosphorylation; Receptors, Glucocorticoid; Recombinant Proteins; Serine; Transcription, Genetic; Ultraviolet Rays | 2002 |
Characterization of the phosphorylation status of the hepatitis B virus X-associated protein 2.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Chlorocebus aethiops; COS Cells; Hepatitis B virus; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Peptide Mapping; Phosphopeptides; Phosphorylation; Proteins; Recombinant Fusion Proteins; Serine; Transfection | 2002 |
Electrospray ionization mass spectrometry of serine/alanine conjugated 5'-UMP and 3',5'-dithymidine phosphoramidates.
Topics: Alanine; Esters; Serine; Spectrometry, Mass, Electrospray Ionization; Thymidine Monophosphate; Uridine Monophosphate | 2002 |
Serine 331 is major site of phosphorylation and desensitization induced by protein kinase C in thromboxane receptor alpha.
Topics: Alanine; Embryo, Mammalian; Humans; Kidney; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Kinase C; Receptors, Thromboxane; Serine; Thromboxane A2 | 2002 |
Substrate-induced conformational transition in human phenylalanine hydroxylase as studied by surface plasmon resonance analyses: the effect of terminal deletions, substrate analogues and phosphorylation.
Topics: Alanine; Catalytic Domain; Cyclic AMP-Dependent Protein Kinases; Humans; Phenylalanine; Phenylalanine Hydroxylase; Phosphorylation; Protein Conformation; Sequence Deletion; Serine; Spectrometry, Fluorescence; Surface Plasmon Resonance; Tryptophan | 2003 |
Taste enhancements between various amino acids and IMP.
Topics: Adult; Alanine; Amino Acids; Dose-Response Relationship, Drug; Female; Glycine; Humans; Inosine Monophosphate; Male; Phenyl Ethers; Propionates; Serine; Taste; Taste Buds; Taste Threshold; Time Factors | 2002 |
Amino acid content of cell cultures infected with Cowdria ruminantium propagated in a protein-free medium.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Bacteriological Techniques; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media, Serum-Free; Ehrlichia ruminantium; Glutamine; Glycine; Heartwater Disease; Proline; Ruminants; Serine; Tryptophan | 2002 |
Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Blotting, Western; Cell Cycle; Chromosome Segregation; Cytoskeletal Proteins; DNA, Complementary; Escherichia coli; G2 Phase; Genotype; Glutathione Transferase; Humans; Mitosis; Molecular Sequence Data; Mutation; NIMA-Related Kinases; Nuclear Proteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Temperature; Time Factors; Tumor Cells, Cultured | 2002 |
The activity of the Arabidopsis bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase enzyme of lysine catabolism is regulated by functional interaction between its two enzyme domains.
Topics: Alanine; Arabidopsis; Aspartic Acid; Casein Kinase II; Chromatography, Gel; Dimerization; Dose-Response Relationship, Drug; Egtazic Acid; Lysine; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Recombinant Proteins; Saccharopine Dehydrogenases; Serine; Sodium Chloride; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2002 |
Analysis of ligand-stimulated CC chemokine receptor 5 (CCR5) phosphorylation in intact cells using phosphosite-specific antibodies.
Topics: Alanine; Animals; Cell Line; Cell Movement; Chemokine CCL5; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epitopes; Humans; Hydrogen-Ion Concentration; Immunoblotting; Immunoenzyme Techniques; Ligands; Microscopy, Fluorescence; Mutation; Pertussis Toxin; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Serine-Threonine Kinases; Rats; Receptors, CCR5; Serine; Time Factors; Tumor Cells, Cultured; Tyrosine | 2003 |
Posttranslational modification of serine to formylglycine in bacterial sulfatases. Recognition of the modification motif by the iron-sulfur protein AtsB.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Arylsulfatases; beta-Galactosidase; Blotting, Western; Cysteine; Cytosol; Dose-Response Relationship, Drug; Escherichia coli; Glutathione Transferase; Glycine; Iron-Sulfur Proteins; Klebsiella pneumoniae; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Protein Binding; Protein Processing, Post-Translational; Protein Sorting Signals; Serine; Subcellular Fractions; Sulfatases; Two-Hybrid System Techniques | 2003 |
Dehydroalanine-based inhibition of a peptide epimerase from spider venom.
Topics: Alanine; Amino Acid Isomerases; Amino Acid Sequence; Amino Acids; Animals; Catalysis; Hydrochloric Acid; Inhibitory Concentration 50; Molecular Mimicry; Peptides; Polyamines; Ribosomes; Serine; Spider Venoms; Spiders; Stereoisomerism; Structure-Activity Relationship | 2002 |
Impaired desensitization of a mutant adrenocorticotropin receptor associated with apparent constitutive activity.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Alanine; Animals; Cell Line; Cushing Syndrome; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression; Humans; Iodine Radioisotopes; Kinetics; Mice; Mutation; Phosphorylation; Receptor, Melanocortin, Type 2; Receptors, Corticotropin; Serine; Signal Transduction; Structure-Activity Relationship; Transfection | 2002 |
An expanded V2 receptor retention signal.
Topics: Alanine; Amino Acid Motifs; Cell Line; Cytoplasm; Humans; Ligands; Mutagenesis; Mutagenesis, Site-Directed; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Receptors, Vasopressin; Serine; Signal Transduction; Threonine; Time Factors; Transfection | 2002 |
Molecular basis of partial agonism: orientation of indoleamine ligands in the binding pocket of the human serotonin 5-HT2A receptor determines relative efficacy.
Topics: Alanine; Amino Acid Substitution; Animals; Binding Sites; Bufotenin; Chlorocebus aethiops; COS Cells; Models, Molecular; Mutation; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serine; Serotonin; Structure-Activity Relationship | 2003 |
Chromophore environment provides clue to "kindling fluorescent protein" riddle.
Topics: Alanine; Animals; Cloning, Molecular; Escherichia coli; Green Fluorescent Proteins; Luminescent Proteins; Microscopy, Fluorescence; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Sea Anemones; Serine; Spectrophotometry; Tyrosine | 2003 |
Structural and thermodynamic studies on a salt-bridge triad in the NADP-binding domain of glutamate dehydrogenase from Thermotoga maritima: cooperativity and electrostatic contribution to stability.
Topics: Alanine; Arginine; Binding Sites; Crystallography, X-Ray; Cysteine; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Guanidine; Lysine; Mutagenesis, Site-Directed; NADP; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Salts; Serine; Static Electricity; Structure-Activity Relationship; Thermodynamics; Thermotoga maritima; Urea | 2002 |
Characterization of the S272A,D site-directed mutations of O-acetylserine sulfhydrylase: involvement of the pyridine ring in the alpha,beta-elimination reaction.
Topics: Alanine; Aspartic Acid; Binding Sites; Catalysis; Circular Dichroism; Cysteine Synthase; Deuterium; Hydrogen Bonding; Kinetics; Mutagenesis, Site-Directed; Pyridines; Pyridoxal Phosphate; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity | 2003 |
Large-scale context in protein folding: villin headpiece.
Topics: Alanine; Algorithms; Amino Acid Sequence; Carrier Proteins; Computer Simulation; Forecasting; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Microfilament Proteins; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurofilament Proteins; Peptide Fragments; Protein Conformation; Protein Folding; Protein Structure, Secondary; Serine; Thermodynamics | 2003 |
Mycobacterium bovis BCG vaccines exhibit defects in alanine and serine catabolism.
Topics: Alanine; Alanine Dehydrogenase; Amino Acid Oxidoreductases; Animals; BCG Vaccine; Cattle; Culture Media; Frameshift Mutation; Glutamate-Ammonia Ligase; L-Serine Dehydratase; Molecular Sequence Data; Mycobacterium bovis; Serine | 2003 |
Phosphorylation of serine 276 is essential for p65 NF-kappaB subunit-dependent cellular responses.
Topics: Active Transport, Cell Nucleus; Alanine; Animals; Cell Death; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Fibroblasts; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Interleukin-1; Interleukin-6; Mice; Mice, Knockout; NF-kappa B; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Serine; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2003 |
Dissection of the EntF condensation domain boundary and active site residues in nonribosomal peptide synthesis.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Binding Sites; Catalysis; Cysteamine; Enterobactin; Escherichia coli Proteins; Genetic Complementation Test; Histidine; Hydroxybenzoates; Ligases; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Peptide Biosynthesis; Peptide Fragments; Peptide Synthases; Protein Structure, Tertiary; Serine | 2003 |
Phosphorylation of serine 1106 in the catalytic domain of topoisomerase II alpha regulates enzymatic activity and drug sensitivity.
Topics: Alanine; Amino Acid Sequence; Antigens, Neoplasm; Casein Kinase II; Casein Kinases; Catalytic Domain; Chelating Agents; Cloning, Molecular; Consensus Sequence; DNA Primers; DNA Topoisomerases, Type II; DNA-Binding Proteins; Doxorubicin; Egtazic Acid; HL-60 Cells; Humans; Kinetics; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylation; Phosphoserine; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Proteins; Saccharomyces cerevisiae; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2003 |
Development of an efficient "substrate-trapping" mutant of Src homology phosphotyrosine phosphatase 2 and identification of the epidermal growth factor receptor, Gab1, and three other proteins as target substrates.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Alanine; Animals; Aspartic Acid; Cell Line; COS Cells; Cysteine; ErbB Receptors; Helminth Proteins; Humans; Immunoblotting; Mice; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Mutation; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Serine; Signal Transduction; src Homology Domains; Transfection | 2003 |
Structural and kinetic analysis of catalysis by a thiamin diphosphate-dependent enzyme, benzoylformate decarboxylase.
Topics: Alanine; Binding Sites; Binding, Competitive; Carboxy-Lyases; Catalysis; Circular Dichroism; Crystallography, X-Ray; Enzyme Inhibitors; Histidine; Kinetics; Ligands; Mandelic Acids; Mutagenesis, Site-Directed; Pseudomonas putida; Serine; Spectrophotometry; Thiamine Pyrophosphate | 2003 |
Reaction of 1-amino-2-methylenecyclopropane-1-carboxylate with 1-aminocyclopropane-1-carboxylate deaminase: analysis and mechanistic implications.
Topics: Alanine; Amino Acid Sequence; Carbon-Carbon Lyases; Carboxylic Acids; Catalysis; Chromatography, High Pressure Liquid; Cloning, Molecular; Crotonates; Cyclopropanes; Cysteine; Dithionitrobenzoic Acid; Glycine; Kinetics; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Pseudomonas; Recombinant Proteins; Serine; Titrimetry | 2003 |
Mechanism of human S-adenosylmethionine decarboxylase proenzyme processing as revealed by the structure of the S68A mutant.
Topics: Adenosylmethionine Decarboxylase; Alanine; Binding Sites; Buffers; Catalysis; Computer Simulation; Crystallography, X-Ray; Enzyme Precursors; Glutamine; Humans; Hydrogen Bonding; Models, Molecular; Mutagenesis, Site-Directed; Oxazoles; Oxygen; Protein Processing, Post-Translational; Putrescine; Serine; Tromethamine | 2003 |
A model of repression: CTD analogs and PIE-1 inhibit transcriptional elongation by P-TEFb.
Topics: Alanine; Animals; Binding Sites; Binding, Competitive; Blotting, Western; Caenorhabditis elegans; Caenorhabditis elegans Proteins; COS Cells; Cyclin-Dependent Kinase 9; Cyclin-Dependent Kinases; Glutamic Acid; HeLa Cells; Histidine; Humans; Models, Genetic; Mutation; Nuclear Proteins; Peptides; Phosphorylation; Plasmids; Positive Transcriptional Elongation Factor B; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Ribonucleases; RNA Polymerase II; Serine; Transcription, Genetic; Transcriptional Activation; Transfection | 2003 |
Enantioselective synthesis of alpha-methyl-D-cysteine and lanthionine building blocks via alpha-methyl-D-serine-beta-lactone.
Topics: Alanine; Cysteine; Lactones; Models, Molecular; Molecular Conformation; Molecular Structure; Serine; Sulfides | 2003 |
Synthesis of serine/alanine conjugated 3',5'-TpT.
Topics: Alanine; Amides; Deoxyribonucleosides; Phosphoramides; Phosphoric Acids; Serine | 2003 |
Synthesis of hydroxymethylglutathione from glutathione and L-serine catalyzed by carboxypeptidase Y.
Topics: Alanine; Carboxypeptidases; Catalysis; Cathepsin A; Chromatography, High Pressure Liquid; Glutathione; Hydrogen-Ion Concentration; Hydroxylation; Serine; Yeasts | 2003 |
Central role of a serine phosphorylation site within duck hepatitis B virus core protein for capsid trafficking and genome release.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Binding Sites; Blotting, Western; Capsid; Cell Nucleus; Centrifugation, Density Gradient; Chickens; DNA, Circular; DNA, Viral; Hepatitis B Virus, Duck; Hydrogen Bonding; Microscopy, Confocal; Mutation; Phosphorylation; Precipitin Tests; Serine; Transfection | 2003 |
Phosphorylation at serine 75 is required for UV-mediated degradation of human Cdc25A phosphatase at the S-phase checkpoint.
Topics: Alanine; Blotting, Western; cdc25 Phosphatases; Cell Line; Checkpoint Kinase 1; Checkpoint Kinase 2; Cyclin E; DNA; DNA Damage; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; HeLa Cells; Histidine; Humans; Models, Biological; Mutation; Peptide Mapping; Phosphorylation; Plasmids; Precipitin Tests; Protein Kinases; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; S Phase; Serine; Time Factors; Transfection; Tumor Cells, Cultured; Ultraviolet Rays | 2003 |
Dual phosphorylation controls Cdc25 phosphatases and mitotic entry.
Topics: 14-3-3 Proteins; Alanine; Amino Acid Substitution; Antineoplastic Agents; cdc25 Phosphatases; DNA Damage; G2 Phase; HeLa Cells; Humans; Mitosis; Mutagenesis, Site-Directed; Nocodazole; Phosphorylation; Point Mutation; Protein Binding; Radiation, Ionizing; Serine; Tyrosine 3-Monooxygenase | 2003 |
The crystal structure, mutagenesis, and activity studies reveal that patatin is a lipid acyl hydrolase with a Ser-Asp catalytic dyad.
Topics: Alanine; Amino Acid Substitution; Animals; Aspartic Acid; Carboxylic Ester Hydrolases; Catalytic Domain; Cloning, Molecular; Coleoptera; Crystallography, X-Ray; Humans; Isoenzymes; Larva; Models, Molecular; Mutagenesis, Site-Directed; Phospholipases A; Pichia; Plant Proteins; Protein Structure, Secondary; Serine | 2003 |
Mutational analysis of the human FATE gene in 144 infertile men.
Topics: Adult; Alanine; Amino Acid Sequence; Animals; Arginine; Cysteine; DNA Mutational Analysis; DNA Primers; DNA-Binding Proteins; Exons; Humans; Infertility, Male; Introns; Karyotyping; Male; Molecular Sequence Data; Mutation; Pedigree; Polymerase Chain Reaction; Polymorphism, Genetic; Serine; Threonine; Transcription Factors; X Chromosome | 2003 |
The role of two novel regulatory sites in the activation of the cGMP-dependent protein kinase from Plasmodium falciparum.
Topics: Alanine; Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding, Competitive; Conserved Sequence; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Gene Duplication; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmodium falciparum; Protein Binding; Protozoan Proteins; Recombinant Proteins; Serine; Thionucleotides; Threonine | 2003 |
Kennedy's disease. Phosphorylation of the polyglutamine-expanded form of androgen receptor regulates its cleavage by caspase-3 and enhances cell death.
Topics: Alanine; Amino Acid Substitution; Base Sequence; Caspase 3; Caspases; Cell Death; Cell Line; DNA Primers; Enzyme Activation; Enzyme Inhibitors; Humans; Mitogen-Activated Protein Kinases; Muscular Atrophy, Spinal; Mutagenesis, Site-Directed; Peptides; Phosphorylation; Polymerase Chain Reaction; Receptors, Androgen; Recombinant Proteins; Serine; Transfection; Trinucleotide Repeat Expansion | 2003 |
Ras-induced serine phosphorylation of the focal adhesion protein paxillin is mediated by the Raf-->MEK-->ERK pathway.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Animals; Cytoskeletal Proteins; Focal Adhesions; Genes, ras; Mice; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Mutation; Paxillin; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins c-raf; Sequence Homology, Amino Acid; Serine; Signal Transduction | 2003 |
Key roles of Phe1112 and Ser1115 in the pore-forming IIIS5-S6 linker of L-type Ca2+ channel alpha1C subunit (CaV 1.2) in binding of dihydropyridines and action of Ca2+ channel agonists.
Topics: Alanine; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Isradipine; Phenylalanine; Point Mutation; Protein Subunits; Pyrroles; Rats; Repetitive Sequences, Nucleic Acid; Serine | 2003 |
Rim, a component of the presynaptic active zone and modulator of exocytosis, binds 14-3-3 through its N terminus.
Topics: 14-3-3 Proteins; Adaptor Proteins, Signal Transducing; Alanine; Alkaline Phosphatase; Amino Acid Motifs; Amino Acid Sequence; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chromaffin Cells; Cross-Linking Reagents; Cysteine; Dose-Response Relationship, Drug; Exocytosis; Glutathione Transferase; GTP-Binding Proteins; Humans; Models, Genetic; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Neurons; PC12 Cells; Phosphoric Monoester Hydrolases; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; rab GTP-Binding Proteins; rab3 GTP-Binding Proteins; Rabphilin-3A; Rats; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Temperature; Transfection; Two-Hybrid System Techniques; Tyrosine 3-Monooxygenase; Vesicular Transport Proteins; Zinc Fingers | 2003 |
Negative charge at the consensus sequence for the serum- and glucocorticoid-inducible kinase, SGK1, determines pH sensitivity of the renal outer medullary K+ channel, ROMK1.
Topics: Alanine; Animals; Aspartic Acid; Cells, Cultured; Consensus Sequence; Electric Conductivity; Hydrogen-Ion Concentration; Immediate-Early Proteins; Mutagenesis, Site-Directed; Nuclear Proteins; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Serine-Threonine Kinases; Serine; Xenopus | 2003 |
Glycine facilitates transmitter release at developing synapses: a patch clamp study from Purkinje neurons of the newborn rat.
Topics: Acetylcholine; Alanine; Anesthetics, Local; Animals; Animals, Newborn; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Electric Conductivity; Excitatory Postsynaptic Potentials; Glycine; Glycine Agents; In Vitro Techniques; Neural Inhibition; Neurotransmitter Agents; Patch-Clamp Techniques; Potassium; Purkinje Cells; Rats; Rats, Wistar; Serine; Strychnine; Synapses; Synaptic Transmission; Taurine; Tetrodotoxin; Time Factors; Vasodilator Agents | 2003 |
L-Serine, D- and L-proline and alanine as respiratory substrates of Helicobacter pylori: correlation between in vitro and in vivo amino acid levels.
Topics: 2,6-Dichloroindophenol; Alanine; Amino Acids; Ammonia; Gastric Juice; Helicobacter pylori; Humans; In Vitro Techniques; Oxidation-Reduction; Oxygen Consumption; Proline; Pyruvic Acid; Serine; Stereoisomerism | 2003 |
Gating competence of constitutively open CLC-0 mutants revealed by the interaction with a small organic Inhibitor.
Topics: 2,4-Dichlorophenoxyacetic Acid; Alanine; Animals; Binding, Competitive; Chloride Channels; Glutamic Acid; Homeostasis; Ion Channel Gating; Kinetics; Linear Models; Models, Biological; Mutation; Oocytes; Serine; Torpedo; Xenopus | 2003 |
Steroidogenic factor-1 and the gonadotrope-specific element enhance basal and pituitary adenylate cyclase-activating polypeptide-stimulated transcription of the human glycoprotein hormone alpha-subunit gene in gonadotropes.
Topics: Alanine; Animals; Cell Line; Cyclic AMP; DNA-Binding Proteins; Fushi Tarazu Transcription Factors; Gene Expression Regulation; Glycoprotein Hormones, alpha Subunit; Homeodomain Proteins; Humans; Mice; Mitogen-Activated Protein Kinases; Mutation; Neuropeptides; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; Promoter Regions, Genetic; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; Response Elements; Serine; Signal Transduction; Steroidogenic Factor 1; Transcription Factors; Transcription, Genetic | 2003 |
Gas-phase basicity of glycine, alanine, proline, serine, lysine, histidine and some of their peptides by the thermokinetic method.
Topics: Alanine; Amino Acids; Gases; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Peptides; Proline; Protons; Serine; Thermodynamics | 2003 |
On the structural and functional importance of the highly conserved Glu56 of Thermus thermophilus L4 ribosomal protein.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Catalytic Domain; Glutamic Acid; Glycine; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Structure, Secondary; Ribosomal Proteins; Ribosomes; Sequence Alignment; Serine; Thermus thermophilus | 2003 |
Concerted motions of the integrin-binding loop and the C-terminal tail of the non-RGD disintegrin obtustatin.
Topics: Alanine; Amino Acid Motifs; Collagen; Hydrogen Bonding; Integrin alpha1beta1; Integrins; Magnetic Resonance Spectroscopy; Models, Molecular; Models, Statistical; Peptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serine; Threonine; Viper Venoms | 2003 |
Essential glycine in the proton channel of Escherichia coli transhydrogenase.
Topics: Alanine; Amino Acid Sequence; Catalysis; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glycine; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; NADP Transhydrogenases; Protein Conformation; Protein Structure, Tertiary; Protons; Serine | 2003 |
[Comparative study of the inhibition of E. coli (strain Monod) by beta 2-d. l. thienylalanine and beta-threo-d. l. phenylserine].
Topics: Alanine; Escherichia coli; Phenylalanine; Serine | 1952 |
The alanine, cystine, glycine and serine content of meat.
Topics: Alanine; Cystine; Glycine; Meat; Serine | 1953 |
A comparison of alanine and glucose as precursors of serine and glycine.
Topics: Alanine; Carbohydrate Metabolism; Glucose; Glycine; Serine | 1956 |
Formation of serine hydroxypryuvate and L-alanine.
Topics: Alanine; Pyruvates; Serine; Transaminases | 1956 |
The nutrition of animal tissues cultivated in vitro. IV. Amino acid requirements of chick embryonic heart fibroblasts.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Fibroblasts; Glycine; Histidine; Hydroxyproline; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
The amino acid requirements of rabbit fibroblasts, strain RM3-56.
Topics: Alanine; Amino Acids; Animals; Arginine; Cystine; Fibroblasts; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Rabbits; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
Contributions to silkworm biochemistry. VIII. Conversion of pyruvate into alanine, glycine and serine of silkfibroin.
Topics: Alanine; Animals; Bombyx; Fabaceae; Glycine; Proteins; Pyruvates; Pyruvic Acid; Serine | 1959 |
[Contributions to silkworm biochemistry. XVI. Conversion of threonine into the glycine, serine and alanine of silk fibroin].
Topics: Alanine; Amino Acids; Animals; Bombyx; Fibroins; Glycine; Insecta; Proteins; Serine; Silk; Threonine | 1960 |
Metabolism of alanine, serine and valine in adipose tissue.
Topics: Adipose Tissue; Alanine; Humans; Serine; Valine | 1962 |
Amino acids, amino sugars and sugars present in the cell wall of some strains of Streptococcus pyogenes.
Topics: Alanine; Amino Acids; Amino Sugars; Arginine; Aspartic Acid; Cell Wall; Cysteine; Glucosamine; Glutamates; Glycine; Hexosamines; Isoleucine; Leucine; Lysine; Serine; Streptococcus pyogenes; Threonine; Valine | 1962 |
[On amino acid metabolism in blood diseases with special reference to aplastic anemia].
Topics: Alanine; Amino Acids; Anemia; Anemia, Aplastic; Glutamates; Glycine; Humans; Hydroxyproline; Serine; Threonine | 1962 |
Nematode biochemistry. II. Biosynthesis of amino acids.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Nematoda; Serine; Threonine; Tyrosine; Valine | 1962 |
Mechanism of action of O-carbamyl-D-serine, a new member of cell wall synthesis inhibitors.
Topics: Alanine; Anti-Bacterial Agents; Antibiotics, Antitubercular; Bacillus subtilis; Cell Wall; Dermatologic Agents; Glutamates; Glutamine; Glycine; Penicillin G; Serine; Staphylococcus | 1963 |
[Thin layer chromatographic separation of amino acids on cellulose layers].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Methionine; Serine; Tryptophan; Tyrosine; Valine | 1962 |
[Contributions to the biochemistry of the silk-worm. XXVI. Utilization of glucose for the synthesis of fibroin by Bombyx mori I].
Topics: Alanine; Animals; Aspartic Acid; Bombyx; Fibroins; Glucose; Glutamates; Glycine; Helminthiasis; Helminths; Pyruvates; Serine; Silk | 1962 |
VARIATION OF FREE AMINO ACIDS IN CORCYRA CEPHALONICA ST. (RICE MOTH LARVAE) DURING SOME B VITAMIN DEFICIENCIES.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chromatography; Glutamates; Glycine; Insecta; Larva; Leucine; Moths; Niacin; Phenylalanine; Research; Riboflavin Deficiency; Serine; Thiamine Deficiency; Tyrosine; Valine; Vitamin B 6 Deficiency; Vitamin B Deficiency | 1963 |
BIOSYNTHESIS OF SERINE IN ESCHERICHIA COLI AND SALMONELLA TYPHIMURIUM.
Topics: Alanine; Autoradiography; Carbon Isotopes; Chromatography; Escherichia coli; Glucose; Glyceric Acids; Glycerophosphates; Glycine; Ketoglutaric Acids; Metabolism; NAD; Oxidoreductases; Phosphoric Monoester Hydrolases; Pyruvates; Research; Salmonella typhimurium; Serine; Valine | 1963 |
[MECHANISMS OF AMINO ACID SYNTHESIS IN LEAVES. STUDIES USING RADIOCARBON].
Topics: Alanine; Amino Acids; Aminobutyrates; Ammonium Compounds; Asparagine; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Chromatography; Darkness; Glutamates; Glutamine; Glycine; Light; Methionine; Nitrates; Plant Proteins; Proteins; Quaternary Ammonium Compounds; Research; Serine; Threonine | 1963 |
[DYNAMIC EQUILIBRIUM OF PROTEINS DURING INCUBATION OF ADIPOSE TISSUE].
Topics: Adipose Tissue; Alanine; Aspartic Acid; Carbon Isotopes; Chromatography; Citric Acid Cycle; Glucose; Glutamates; Glutamine; Insulin; Leucine; Lipid Metabolism; Proteins; Rats; Research; Serine; Tissue Culture Techniques; Water-Electrolyte Balance | 1963 |
COMPARATIVE BIOCHEMISTRY OF HEPATOMAS. V. STUDIES ON AMINO ACID INCORPORATION IN LIVER TUMORS OF DIFFERENT GROWTH RATES.
Topics: Alanine; Amino Acids; Aspartic Acid; Carcinoma, Hepatocellular; Glycine; Histocytochemistry; Isoleucine; Liver Neoplasms; Liver Regeneration; Mice; Neoplasms, Experimental; Proteins; Research; Serine; Valine | 1963 |
STUDIES ON COLLETOTRICHUM CAPSICI III. THE EFFECT OF INITIAL PH ON THE GROWTH AND AMINO ACID COMPOSITION.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Chromatography; Colletotrichum; Cysteine; Fungi; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Phenylalanine; Research; Serine; Tyrosine | 1963 |
SPECIFICITY OF PEPSIN AND ITS DEPENDENCE ON A POSSIBLE 'HYDROPHOBICBINDING SITE'.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pepsin A; Peptides; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
GAS CHROMATOGRAPHY OF AMINO ACIDS. 1. ANALYSIS OF THE MIXTURE OF METHYL-NTRIFLUOROACETYL DERIVATIVES.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography; Chromatography, Gas; Fluoroacetates; Glutamates; Glycine; Hydroxyproline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1963 |
THE EFFECT OF ETHANOL AND ELECTRICAL STIMULATION ON THE AMINO ACID METABOLISM OF RAT-BRAIN-CORTEX SLICES IN VITRO.
Topics: Alanine; Alcoholic Intoxication; Amino Acids; Aminobutyrates; Ammonium Chloride; Aspartic Acid; Brain; Carbon Isotopes; Cerebral Cortex; Electric Stimulation; Electrophysiology; Ethanol; Glutamates; Glutamine; Glycine; In Vitro Techniques; Proteins; Rats; Research; Serine; Taurine; Toxicology | 1963 |
SELENOAMINO ACIDS: DECREASE OF RADIATION DAMAGE TO AMINO ACIDS AND PROTEINS.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acids; Arginine; Cystine; Histidine; Isoleucine; Leucine; Methionine; Organoselenium Compounds; Phenylalanine; Proteins; Radiation-Protective Agents; Ribonucleases; Selenium; Serine | 1964 |
AMINO-ACID CONFIGURATION OF MYCOBACILLIN.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Antifungal Agents; Aspartic Acid; Chemistry Techniques, Analytical; Glutamates; Leucine; Mycobacillin; Proline; Research; Serine; Tyrosine | 1963 |
INHIBITION IN SYNTHESIS OF BETA-ALANINE BY D-SERINE.
Topics: Alanine; Antimetabolites; Aspartic Acid; beta-Alanine; Erwinia; Manometry; Metabolism; Pharmacology; Phenylalanine; Research; Serine | 1963 |
THE NH2-TERMINAL RESIDUES OF THE PROTEINS FROM CELL-FREE EXTRACTS OF E. COLI.
Topics: Alanine; Aspartic Acid; Bacterial Proteins; Chromatography; Electrophoresis; Escherichia coli; Glutamates; Methionine; Phenytoin; Proteins; Research; Serine; Threonine | 1963 |
ROLE OF SERINE IN CHYMOTRYPSIN ACTION. CONVERSION OF THE ACTIVE SERINE TO DEHYDROALANINE.
Topics: Alanine; Chymotrypsin; Proteins; Research; Serine | 1963 |
MECHANISM OF ACTION OF O-CARBAMYL-D-SERINE.
Topics: Alanine; Anti-Bacterial Agents; Bacillus subtilis; Carbohydrate Metabolism; Escherichia coli; Glutamates; Glycine; Lysine; Pharmacology; Purines; Research; Serine; Staphylococcus | 1963 |
EFFECT OF ALANINE AND THREONINE ON THE SYNTHESIS OF SERINE BY LEUCONOSTOC MESENTEROIDES.
Topics: Alanine; Amino Acids; Bacterial Proteins; Benzoates; Formates; Glutamine; Glycine; Histidine; Leuconostoc; Leucovorin; Proteins; Research; Serine; Threonine | 1963 |
THE INHIBITION OF CEREBRAL DIGLYCINASE BY ALPHA-AMINO-, ALPHA-KETO- AND ALPHA-HYDROXY ACIDS.
Topics: Alanine; Aminobutyrates; Animals; Arginine; Aspartic Acid; Brain; Cobalt; Enzyme Inhibitors; Histidine; Hydroxy Acids; Keto Acids; Leucine; Methionine; Mice; Peptide Hydrolases; Peptides; Pharmacology; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Valine | 1963 |
OXIDATION OF L-AMINO ACIDS AND INCORPORATION INTO PROTEIN IN HOMOGENATES OF BRAIN AT TWO STAGES OF DEVELOPMENT.
Topics: Alanine; Amino Acids; Arginine; Autoradiography; Brain; Carbon Isotopes; Chromatography; Glycine; Histidine; Isoleucine; Keto Acids; Leucine; Lysine; Mice; Nerve Tissue Proteins; Phenylalanine; Proline; Proteins; Pyruvates; Research; Serine; Threonine; Valine | 1963 |
[ON THE QUANTITATIVE DETERMINATION OF AMINO ACIDS USING HIGH VOLTAGE ELECTROPHORESIS].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Blood Protein Electrophoresis; Glutamates; Histidine; Leucine; Lysine; Methionine; Ornithine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
[QUANTITATIVE STUDY OF THE FATE OF AMINO ACIDS UNDER THE INFLUENCE OF THE FREE HYDROXYL RADICAL].
Topics: Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Biochemical Phenomena; Biochemistry; Carbon Isotopes; Chromatography; Glutamates; Hydroxides; Hydroxyl Radical; Phenylalanine; Research; Serine; Tryptophan | 1963 |
[CONTRIBUTION TO THE STUDY OF RIBONUCLEOPROTEINS OF NORMAL AND NEOPLASTIC TISSUES].
Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Isoleucine; Leucine; Liver; Lysine; Mice; Neoplasm Proteins; Neoplasms; Nucleoproteins; Phenylalanine; Rats; Research; Ribonucleoproteins; RNA; RNA, Neoplasm; Serine; Threonine; Tyrosine; Valine | 1963 |
STUDIES ON MORPHINE. IV. EFFECTS OF SOME METABOLITES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
Topics: Alanine; Cyanides; Fluoroacetates; Glutamine; Iodoacetates; Mice; Morphine; NAD; Nalorphine; Niacin; Niacinamide; Pharmacology; Pyridines; Pyridoxine; Research; Serine; Toxicology; Tryptophan | 1963 |
[SPECIFICITY OF ACTIVATION ENZYMES WITH RESPECT TO RIBONUCLEIC ACIDS ESTERIFIED BY AMINO ACIDS].
Topics: Alanine; Amino Acids; Animals; Carbon Isotopes; Chromatography; Cysteine; Escherichia coli; Ligases; Methionine; Nucleoproteins; Poultry; Proteins; Research; RNA; RNA, Bacterial; Serine; Sulfur Isotopes; Tyrosine | 1963 |
BIOCHEMISTRY OF LUNGS IN RELATION TO SILICOSIS. II. THE EFFECT OF QUARTZ DUST ON THE PROTEIN AMINO ACIDS OF GUINEA PIG LUNG TISSUE.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Collagen; Cystine; Dust; Glutamates; Glycine; Guinea Pigs; Histidine; Hydroxyproline; Isoleucine; Leucine; Lung; Lysine; Methionine; Phenylalanine; Proline; Quartz; Research; Serine; Silicon Dioxide; Silicosis; Threonine; Toxicology; Tyrosine; Valine | 1964 |
THE SUBMOLAR QUANTITIES OF N-TERMINALS IN PROTEINS. EFFECT OF SODIUM DODECYL SULFATE ON THE N-TERMINALS OF EGG ALBUMIN AND BOVINE, EQUINE, AND PORCINE GAMMA-GLOBULINS.
Topics: Alanine; Albumins; Animals; Cattle; Chemistry Techniques, Analytical; gamma-Globulins; Glutamates; Horses; Ovalbumin; Proteins; Research; Serine; Sodium Dodecyl Sulfate; Surface-Active Agents; Swine; Threonine; Trypsin | 1964 |
[CONTRIBUTION TO THE STUDY OF EXPERIMENTAL HEPATIC UREOGENESIS].
Topics: Alanine; Dogs; Glycine; Liver; Proteins; Research; Serine; Urea | 1963 |
THE INCORPORATION OF LABELLED CO2 INTO CELLS AND EXTRACTS OF NITROSOMONAS EUROPAEA.
Topics: Adenosine Triphosphate; Alanine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Glycine; Heptoses; Hexoses; Metabolism; NAD; Nitrosomonas; Nitrosomonas europaea; Phosphates; Pyruvates; Research; Serine; Threonine | 1964 |
NITROGEN BALANCES FOR YOUNG ADULT MALES FED TWO SOURCES OF NONESSENTIAL NITROGEN AT TWO LEVELS OF TOTAL NITROGEN INTAKE.
Topics: Alanine; Ammonium Compounds; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Male; Nitrogen; Nitrogen Fixation; Proline; Proteins; Quaternary Ammonium Compounds; Serine | 1964 |
FREE AMINO ACIDS IN PLASMA AND TISSUES OF RATS FED A VITAMIN B6-DEFICIENT DIET.
Topics: Alanine; Amino Acids; Aspartic Acid; Blood; Diet; Glycine; Liver; Muscles; Proteins; Rats; Research; Serine; Vitamin B 6; Vitamin B 6 Deficiency | 1964 |
[RESEARCH ON THE MECHANISM OF SYNTHESIS OF THE AMINO ACIDS IN PLANTS (CHLORELLA VULGARIS). III. CHANGES INDUCED BY THE INTERRUPTION OF ILLUMINATION].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Carbon Isotopes; Chlorella vulgaris; Eukaryota; Glutamates; Glycine; Lighting; Lysine; Proteins; Research; Serine | 1964 |
THE ROLE OF DISPENSABLE AMINO ACIDS IN THE NUTRITION OF THE RAT.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bicarbonates; Caseins; Cystine; Dietary Proteins; Glutamates; Glycine; Growth; Histidine; Isoleucine; Lysine; Methionine; Phenylalanine; Proline; Proteins; Rats; Research; Serine; Tyrosine | 1964 |
THE INFLUENCE OF GLUCOSE ON AMINO ACID CARBON INCORPORATION INTO PROTEINS, FATTY ACIDS, AND CARBON DIOXIDE BY LACTATING RAT MAMMARY GLAND SLICES.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon; Carbon Dioxide; Carbon Isotopes; Chromatography; Fatty Acids; Female; Glucose; Glutamates; Glycine; Humans; Lactation; Leucine; Lipid Metabolism; Lysine; Mammary Glands, Animal; Mammary Glands, Human; Methionine; Phenylalanine; Proteins; Rats; Research; Serine | 1964 |
MIGRATION OF AMINO ACIDS ACROSS THE MEMBRANE OF THE HUMAN ERYTHROCYTE.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport; Carbon Isotopes; Erythrocytes; Glycine; Histidine; Leucine; Methionine; Permeability; Phenylalanine; Proteins; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
DYNAMIC PHENOMENA IN MICROSPHERES FROM THERMAL PROTEINOID.
Topics: Alanine; Arginine; Aspartic Acid; Colloids; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Microspheres; Peptides; Phenylalanine; Photomicrography; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
[SEPARATION OF AMINO ACIDS BY CHROMATOGRAPHY ON THIN LAYERS OF DIETHYLAMINOETHYL CELLULOSE].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
THE INHIBITION OF MITOCHONDRIAL ADENOSINE TRIPHOSPHATASE. 2. THE EFFECTS OF AMINO ACIDS AND SUGARS.
Topics: Adenosine Triphosphatases; Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Enzyme Inhibitors; Fructose; Glutamates; Glycine; Histidine; Hydroxyproline; Isoleucine; Lactose; Liver; Lysine; Methionine; Mitochondria; Oligosaccharides; Pharmacology; Proline; Rats; Research; Serine; Threonine; Valine | 1964 |
AMINO ACID METABOLISM IN RAT BRAIN STUDIED WITH 14C-LABELLED GLUCOSE.
Topics: Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Brain; Carbon Isotopes; Glucose; Glutamates; Glutamine; Glycine; Lead; Nitrophenols; Proteins; Rats; Research; Seizures; Serine; Threonine; Tin; Toxicology | 1964 |
GLYCYLGLYCINE UPTAKE IN STREPTOCOCCI AND A POSSIBLE ROLE OF PEPTIDES IN AMINO ACID TRANSPORT.
Topics: Alanine; Amino Acids; Biological Transport; Carbon Isotopes; Dinitrophenols; Enterococcus faecalis; Glycine; Glycylglycine; Novobiocin; Peptides; Pharmacology; Proteins; Research; Serine | 1964 |
CHROMATOGRAPHIC SEPARATION OF PYRIDOXYL DERIVATIVES OF AMINO ACIDS.
Topics: Alanine; Amines; Amino Acids; Arginine; Aspartic Acid; Chromatography; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Phenylalanine; Pyridines; Pyridoxine; Research; Serine; Threonine; Tyrosine; Valine | 1964 |
PLASMA AMINO ACID PATTERNS IN ALCOHOLISM: THE EFFECTS OF ETHANOL LOADING.
Topics: Alanine; Alcoholism; Amino Acids; Autoanalysis; Biomedical Research; Blood; Ethanol; Genetics, Medical; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Methionine; NAD; NADP; Proline; Proteins; Serine; Toxicology; Valine | 1964 |
AN ANALYSIS OF THE OPTICAL ROTATORY DISPERSION OF POLYPEPTIDES AND PROTEINS.
Topics: Alanine; Animals; Cattle; Chemical Phenomena; Chemistry; Fibrinogen; Globulins; Glutamates; Lysine; Muscle Proteins; Optical Rotatory Dispersion; Peptides; Proline; Proteins; Research; Ribonucleases; Serine; Serum Albumin; Serum Albumin, Bovine | 1964 |
SERUM AMINO ACIDS IN KWASHIORKOR. I. RELATIONSHIP TO CLINICAL CONDITION.
Topics: Alanine; Amino Acids; Biomedical Research; Black People; Blood; Glutamates; Glutamine; Glycine; Infant; Isoleucine; Kwashiorkor; Leucine; Methionine; Phenylalanine; Serine; Threonine; Tyrosine; Uganda; Valine | 1964 |
PERMEATION OF AMINO ACIDS IN MONILIFORMIS AND MACRACANTHORHYNCHUS (ACANTHOCEPHALA).
Topics: Acanthocephala; Alanine; Amino Acids; Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Helminths; Isoleucine; Leucine; Methionine; Moniliformis; Rats; Research; Serine | 1964 |
PREPARATION OF SERINE FROM ALANINE BY A FERRO-ASCORBATE METHOD.
Topics: Alanine; Ascorbic Acid; Chromatography; Hydrogen Peroxide; Iron; Research; Serine | 1964 |
A MULTIVARIATE ANALYSIS OF AMINO-ACID EXCRETIONS.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Biomedical Research; Child; Chromatography; Electronic Data Processing; Glutamine; Glycine; Humans; Intellectual Disability; Multivariate Analysis; Renal Aminoacidurias; Serine; Taurine | 1964 |
RESPONSE OF 1-ASPARTIC-4-CARBOXYLASE TO SELECTED INHIBITORS.
Topics: Alanine; Aspartic Acid; Carbon Dioxide; Carboxy-Lyases; Enzyme Inhibitors; Flavobacterium; Keto Acids; Ketoglutaric Acids; Mitomycin; Mitomycins; Penicillins; Proteins; Pyridoxal Phosphate; Pyruvates; Research; Serine; Vancomycin | 1964 |
[FREE AMINO ACIDS IN THE BLOOD AND URINE OF PATIENTS WITH SOME FORMS OF DERMATOSIS].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Blood; Cystine; Dermatitis; Eczema; Erythema Multiforme; Glutamates; Glycine; Histidine; Lupus Erythematosus, Systemic; Lysine; Proteins; Psoriasis; Renal Aminoacidurias; Serine; Skin Diseases; Taurine; Threonine; Toxicology; Tryptophan; Urticaria | 1964 |
A SIMPLE PREPARATION METHOD FOR DIPHOSPHOMIDAZOLE.
Topics: Alanine; Amides; Calcium Phosphates; Chlorides; Chromatography; Cysteine; Cystine; Glycine; Histidine; Imidazoles; Ion Exchange Resins; Methionine; Phosphates; Phosphorus; Research; Serine; Tryptophan; Tyrosine | 1964 |
NUTRITIONAL FACTORS RELATING TO GROWTH AND OXYTETRACYCLINE FORMATION BY STREPTOMYCES RIMOSUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Cysteine; Cystine; Glutamine; Glycine; Histidine; Isoleucine; Lysine; Metabolism; Methionine; Oxytetracycline; Research; Serine; Streptomyces; Streptomyces rimosus | 1964 |
THE ENZYMATIC SYNTHESIS OF D-ALANYL-D-ALANINE. 3. ON THE INHIBITION OF D-ALANYL-D-ALANINE SYNTHETASE BY THE ANTIBIOTIC D-CYCLOSERINE.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Anti-Bacterial Agents; Carbon Isotopes; Chromatography; Cycloserine; Enterococcus faecalis; Enzyme Inhibitors; Ligases; Magnesium; Oxazoles; Pharmacology; Potassium; Research; Serine; Threonine | 1964 |
GLYCINE-SPECIFIC TRANSFER RIBONUCLEIC ACID IN THE POSTERIOR SILKGLAND OF BOMBYX MORI.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Bombyx; Carbon Isotopes; Fibroins; Glutamates; Glycine; Research; RNA; RNA, Transfer; Serine | 1964 |
INOTROPIC ACTIVITY OF A SERIES OF AMINO ACIDS.
Topics: Adrenal Glands; Alanine; Amino Acids; Blood Pressure; Cysteine; Dogs; Glycine; Heart; Leucine; Methionine; Pharmacology; Research; Sensory Receptor Cells; Serine; Threonine | 1964 |
[FREE PLASMA AMINO ACIDS IN LIVER CIRRHOSIS AND HEPATITIS].
Topics: Alanine; Amino Acids; Blood; Chromatography; Glutamine; Glycine; Hepatitis; Humans; Ion Exchange Resins; Liver Cirrhosis; Methionine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine | 1964 |
A COMPARISON OF (14C)GLYOXYLATE AND (14C)ACETATE METABOLISM IN GERMINATING FATTY SEEDS.
Topics: Acetates; Alanine; Aspartic Acid; Carbohydrate Metabolism; Carbon Dioxide; Carbon Isotopes; Citrates; Flax; Glutamates; Glutamine; Glycine; Glyoxylates; Lipids; Malates; Oxalates; Plants, Edible; Research; Ricinus; Seeds; Serine; Succinates | 1964 |
MYOSIN: AN N-ACETYLATED PROTEIN.
Topics: Acetates; Alanine; Aspartic Acid; Chromatography; Methionine; Muscle Proteins; Myosins; Research; Serine | 1964 |
MYOGLOBIN FREE-RADICALS.
Topics: Alanine; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Glycine; Histidine; Hydrogen Peroxide; Leucine; Myoglobin; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
SOME PROPERTIES OF METHANOBACTERIUM OMELIANSKII FERREDOXIN.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacteria; Chemistry Techniques, Analytical; Cystine; Ferredoxins; Glutamates; Glycine; Iron; Lysine; Methanobacterium; Proline; Serine; Spectrophotometry; Sulfides; Threonine; Tyrosine; Valine | 1964 |
LIQUID-LIQUID EXTRACTION IN THE AUTOANALYZER. DETERMINATION OF TAURINE.
Topics: Adrenalectomy; Alanine; Autoanalysis; Automation; Chemistry Techniques, Analytical; Chloroform; Glycine; Liquid-Liquid Extraction; Rats; Research; Serine; Sulfonic Acids; Taurine; Threonine | 1964 |
THE DEVELOPMENTAL SIGNIFICANCE OF ALANINE DEHYDROGENASE IN BACILLUS SUBTILIS.
Topics: Alanine; Alanine Dehydrogenase; Alanine Transaminase; Amino Acid Oxidoreductases; Amino Acids; Aminobutyrates; Ammonia; Aspartate Aminotransferases; Bacillus subtilis; Cysteine; Isoleucine; Leucine; Lyases; Methionine; Mutation; Research; Serine; Spectrophotometry; Spores; Spores, Bacterial; Valine | 1964 |
IMPROVED TECHNIQUE FOR THE PREPARATION OF STREPTOCOCCAL CELL WALLS.
Topics: Alanine; Amino Sugars; Bacteriological Techniques; Bacteriolysis; Cell Wall; Chemistry Techniques, Analytical; Electrons; Galactose; Glucosamine; Glutamates; Glycine; Lysine; Microscopy; Microscopy, Electron; Research; Rhamnose; Serine; Streptococcus | 1964 |
AMINO ACIDS AS PROTECTIVE COMPOUNDS IN ULTRAVIOLET-IRRADIATED HANSENULA WINGEI.
Topics: Alanine; Amino Acids; Arginine; Cysteine; Cystine; Ethionine; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Pichia; Proline; Radiation-Protective Agents; Research; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays; Valine; Yeasts | 1964 |
COMPARATIVE RADIOLABILITY OF AMINO ACIDS OF PROTEINS AND FREE AMINO ACIDS.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Catalase; Chromatography; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Ovalbumin; Phenylalanine; Proteins; Radiation Effects; Research; Serine; Valine | 1964 |
SELENOAMINO ACIDS AS RADIATION PROTECTORS IN VITRO.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acids; Arginine; Cysteine; Cystine; Histidine; In Vitro Techniques; Leucine; Methionine; Phenylalanine; Radiation-Protective Agents; Research; Ribonucleases; Selenium; Serine | 1964 |
SUPPRESSION OF THE INHIBITORY ACTION OF GUANIDINE ON VIRUS MULTIPLICATION BY SOME AMINO ACIDS.
Topics: Alanine; Albumins; Amino Acids; Animals; Cattle; Enterovirus; Foot-and-Mouth Disease Virus; Guanidine; Guanidines; Kidney; Leucine; Methionine; Pharmacology; Protein Hydrolysates; Research; Serine; Threonine; Valine | 1964 |
CATALYTIC REACTIONS INVOLVING AZOMETHINES. IV. RATES AND EQUILIBRIA OF IMINE FORMATION WITH PYRIDINE-4-ALDEHYDE AND VARIOUS AMINO ACIDS.
Topics: Alanine; Aldehydes; Amino Acids; Arginine; Asparagine; Aspartic Acid; Azo Compounds; Biochemical Phenomena; Biochemistry; Glutamates; Glycine; Imines; Leucine; Phenylalanine; Pyridines; Research; Serine; Spectrophotometry; Thiosemicarbazones; Valine | 1964 |
BREAKDOWN OF AMINO ACIDS BY ENTEROBACTERIACEAE. II. STEREOSPECIFICITY OF ALKALIZATION REACTION.
Topics: Alanine; Amino Acids; Enterobacteriaceae; Glutamates; Histidine; Research; Serine; Tryptophan; Valine | 1964 |
RELATIONSHIP OF A BETA-ALANINE-PYRUVIC AMINOTRANSFERASE TO REVERSAL OF D-SERINE INHIBITION OF GROWTH.
Topics: Alanine; Alanine Transaminase; Aspartic Acid; beta-Alanine; Cycloserine; Flavobacterium; Ketoglutaric Acids; Mitomycin; Mitomycins; Pantothenic Acid; Penicillins; Pharmacology; Pyridoxal Phosphate; Pyruvates; Research; Serine; Transaminases; Vancomycin | 1964 |
THREONINE AND SERINE LINKAGES IN MUCOPOLYSACCHARIDES AND GLYCOPROTEINS.
Topics: Alanine; Aminobutyrates; Animals; Cattle; Chemical Phenomena; Chemistry; Glycoproteins; Glycosaminoglycans; Serine; Sharks; Threonine | 1964 |
PRIMARY PRODUCTS OF PHOTOSYNTHESIS IN LEAVES OF CELERY.
Topics: Alanine; Apium; Carbon Dioxide; Carbon Isotopes; Glycine; Mannitol; Phosphates; Photosynthesis; Plant Leaves; Plants; Plants, Edible; Research; Serine; Sucrose | 1964 |
STUDIES ON THE AMINO ACIDS IN YEAST RNA IN BOUND FORM. 3. DINITROPHENYLATION STUDIES ON THE PURIFIED YEAST RNA.
Topics: Alanine; Amino Acids; Aspartic Acid; Chemistry Techniques, Analytical; Chromatography; Dinitrophenols; Electrophoresis; Histidine; Peptides; Research; RNA; RNA, Bacterial; Saccharomyces; Serine; Spectrum Analysis; Ultracentrifugation | 1964 |
[DEGRADATION OF TRYPTOPHAN BY ESCHERICHIA COLI. II. INDIRECT METHODS].
Topics: Alanine; Escherichia coli; Glycine; Indoleacetic Acids; Indoles; Metabolism; Research; Serine; Tryptophan | 1964 |
DILUTE ACID HYDROLYSIS OF PAPAIN. KINETIC STUDIES AND PEPTIDES FROM THE CARBOXYMETHYLATED PROTEIN.
Topics: Alanine; Aspartic Acid; Chromatography; Electrophoresis; Glutamates; Glycine; Hydrolysis; Kinetics; Papain; Peptides; Proteins; Research; Serine; Spectrophotometry; Threonine | 1965 |
BIOSYNTHESIS IN VICIA SATIVA (COMMON VETCH) OF GAMMA-GLUTAMYL-BETA-CYANOALANINE FROM (BETA-14-C)SERINE AND ITS RELATION TO CYANIDE METABOLISM.
Topics: Alanine; Amino Acids; Asparagine; Carbon Isotopes; Chromatography; Cyanides; Dipeptides; Glutamates; Metabolism; Plants; Research; Serine; Vicia sativa | 1964 |
THE UTILIZATION OF C-14O-2 IN THE PRODUCTION OF ACID METABOLITES BY MONILIFORMIS DUBIUS (ACANTHOCEPHALA).
Topics: Acanthocephala; Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Fumarates; Helminths; Lactates; Metabolism; Moniliformis; Phenylhydrazines; Pyruvates; Research; Serine; Succinates | 1965 |
[NEOGLUCOGENESIS IN HEPATOCYTES CULTIVATED IN VITRO].
Topics: Alanine; Animals; Carbohydrate Metabolism; Chick Embryo; Cystine; Fibroblasts; Glucose; Glycine; Hepatocytes; In Vitro Techniques; Insulin; Liver; Liver Glycogen; Research; Serine; Tissue Culture Techniques | 1964 |
[APPLICATION OF THIN-LAYER CHROMATOGRAPHY TO SEQUENCE ANALYSIS OF PEPTIDES. 3. NONDESTRUCTIVE DETECTION OF AMINO ACIDS ON THE THIN-LAYER CHROMATOGRAM].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chromatography; Chromatography, Thin Layer; Histidine; Peptides; Proline; Research; Sequence Analysis; Serine; Tyrosine; Valine | 1964 |
THE MAJOR ALKALINE PROTEINASE OF ASPERGILLUS ORYZAE, ASPERGILLOPEPTIDASE B. II. PARTIAL SPECIFIC VOLUME, MOLECULAR WEIGHT, AND AMINO ACID COMPOSITION.
Topics: Alanine; Amides; Amino Acids; Aspergillus; Aspergillus oryzae; Bacterial Proteins; Buffers; Chemical Phenomena; Chemistry, Physical; Cysteine; Cystine; Densitometry; Endopeptidases; Glycine; Molecular Weight; Nitrogen; Peptide Hydrolases; Research; Serine; Serine Endopeptidases; Tryptophan | 1964 |
BIOGENESIS OF THE N-METHYL GROUP OF PYOCYANINE.
Topics: Alanine; Alkylation; Amino Acids; Anti-Bacterial Agents; Carbon; Carbon Isotopes; Culture Media; Glycerol; Metabolism; Methionine; Phosphates; Pigments, Biological; Pseudomonas aeruginosa; Pyocyanine; Quinic Acid; Research; Serine; Sulfates | 1964 |
MUTATIONALLY INDUCED AMINO ACID SUBSTITUTIONS IN A TRYPTIC PEPTIDE OF THE TRYPTOPHAN SYNTHETASE A PROTEIN.
Topics: Alanine; Amino Acid Substitution; Amino Acids; Aspartic Acid; Autoanalysis; Bacterial Proteins; Biochemical Phenomena; Biochemistry; Carboxypeptidases; Chromatography; Chromosome Mapping; Chymotrypsin; Escherichia coli; Genetic Code; Glycine; Hydro-Lyases; Isoleucine; Leucyl Aminopeptidase; Molecular Biology; Mutation; Papain; Peptides; Protein Hydrolysates; Research; Serine; Trypsin; Tryptophan Synthase | 1965 |
PROTON MAGNETIC RESONANCE SPECTRA OF SOME PROTEINS. I. RIBONUCLEASE, OXIDIZED RIBONUCLEASE, LYSOZYME, AND CYTOCHROME C.
Topics: Alanine; Amino Acids; Cytochromes; Cytochromes c; Glutamine; Magnetic Resonance Spectroscopy; Muramidase; Peptides; Proteins; Protons; Research; Ribonucleases; Serine; Spectrum Analysis | 1965 |
GAS CHROMATOGRAPHY OF VOLATILE AMINO ACID DERIVATIVES. I. ALANINE, GLYCINE, VALINE, LEUCINE, ISOLEUCINE, SERINE AND THREONINE.
Topics: Alanine; Arginine; Chromatography; Chromatography, Gas; Equipment and Supplies; Glycine; Isoleucine; Leucine; Research; Serine; Threonine; Valine | 1965 |
ENZYMATIC PROPERTIES OF ALANINE DEHYDROGENASE OF BACILLUS SUBTILIS.
Topics: Alanine; Alanine Dehydrogenase; Amino Acid Oxidoreductases; Amino Acids; Aminobutyrates; Bacillus subtilis; Benzoates; Caproates; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Cysteine; Isoleucine; Ketoglutaric Acids; Metals; NAD; Oxalates; Pyruvates; Research; Serine; Valine | 1965 |
RELATIONSHIP OF PNH3 OF TUBULAR CELLS TO RENAL PRODUCTION OF AMMONIA.
Topics: Acidosis; Alanine; Amino Acids; Ammonia; Ammonium Chloride; Animals; Aspartic Acid; Body Fluids; Dogs; Fluids and Secretions; Glomerular Filtration Rate; Glutamates; Glutaminase; Glutamine; Glycine; Kidney; Kidney Tubules; Lactates; p-Aminohippuric Acid; Physiology; Research; Serine; Urine | 1965 |
RAT LIVER ENZYME DOES NOT ACTIVATE ACETYLAMINO ACIDS.
Topics: Acetates; Adenosine Triphosphate; Alanine; Amino Acids; Arginine; Diphosphates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Liver; Lysine; Methionine; Phenylalanine; Proline; Rats; Research; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
EFFECT OF AMINO ACIDS ON GROWTH OF SPHAEROTILUS DISCOPHORUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Bacteriological Techniques; Caseins; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Proline; Research; Serine; Sphaerotilus; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
STUDIES ON HUMAN ANTIBODIES. 3. AMINO ACID COMPOSITION OF FOUR ANTIBODIES FROM ONE INDIVIDUAL.
Topics: Alanine; Amino Acids; Antibodies; Arginine; Aspartic Acid; Chemistry Techniques, Analytical; gamma-Globulins; Glutamates; Glycine; Histidine; Immunochemistry; Immunoglobulins; Isoleucine; Leucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1965 |
DECREASE IN APPETITE AND BIOCHEMICAL CHANGES IN AMINO ACID IMBALANCE IN THE RAT.
Topics: Alanine; Amino Acids; Appetite; Biochemical Phenomena; Biochemistry; Diet; Dietary Proteins; Glutamates; Glutens; Isoleucine; Kwashiorkor; Leucine; Liver; Lysine; Muscles; Proline; Rats; Research; Serine; Threonine; Valine | 1965 |
NEMATODE BIOCHEMISTRY. V. INTERMEDIARY METABOLISM AND AMINO ACID INTERCONVERSIONS IN CAENORHABDITIS BRIGGSAE.
Topics: Acetates; Alanine; Amino Acids; Aminobutyrates; Animals; Asparagine; Aspartic Acid; Bicarbonates; Caenorhabditis; Carbon Dioxide; Chromatography; Formates; Glutamates; Glutamine; Glycine; Malates; Nematoda; Phenylalanine; Research; Serine; Taurine; Tyrosine | 1965 |
CHANGES IN THE NERVE CELL PROTEINS IN DOGS DURING RESUSCITATION FROM THE STATE OF CLINICAL DEATH.
Topics: Alanine; Aminobutyrates; Ammonia; Arginine; Asparagine; Brain Chemistry; Cerebral Cortex; Cystine; Death; Dogs; Glutamates; Glutamine; Glycine; Histidine; Histocytochemistry; Hypothermia; Hypothermia, Induced; Leucine; Lysine; Methionine; Nerve Tissue Proteins; Neurons; Pathology; Phenylalanine; Proteins; Research; Resuscitation; Serine | 1965 |
AMINO ACID COMPOSITION AND C-TERMINAL RESIDUES OF ALGAL BILIPROTEINS.
Topics: Alanine; Amino Acids; Biochemical Phenomena; Biochemistry; Chromatography; Chromatography, Gel; Crystallization; Eukaryota; Phycocyanin; Phycoerythrin; Pigments, Biological; Proteins; Research; Serine; Spectrophotometry | 1965 |
MICROBIAL GROWTH ON C1 COMPOUNDS. SYNTHESIS OF CELL CONSTITUENTS BY METHANE- AND METHANOL-GROWN PSEUDOMONAS METHANICA.
Topics: Alanine; Alcohols; Aspartic Acid; Bicarbonates; Chromatography; Citrates; Ethanol; Fructose; Glucose; Glutamates; Glycine; Heptoses; Hexosephosphates; Malates; Metabolism; Methane; Methanol; Propionates; Pseudomonas; Research; Ribose; Serine | 1965 |
ENTRY OF GLUCOSE CARBON INTO AMINO ACIDS OF RAT BRAIN AND LIVER IN VIVO AFTER INJECTION OF UNIFORMLY 14-C-LABELLED GLUCOSE.
Topics: Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Brain; Brain Chemistry; Carbohydrate Metabolism; Carbon; Carbon Isotopes; Chromatography; Glucose; Glutamates; Glutamine; Glycine; Liver; Rats; Research; Serine | 1965 |
Stimulation by surangin B of endogenous amino acid release from synaptosomes.
Topics: Alanine; Amino Acids; Animals; Brain; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carboxin; Coumarins; Fungicides, Industrial; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Insecticides; Male; Mice; Mitochondria; Multienzyme Complexes; Presynaptic Terminals; Rotenone; Serine; Synaptosomes; Taurine; Uncoupling Agents | 2003 |
Contribution of wild-type transthyretin to hereditary peripheral nerve amyloid.
Topics: Alanine; Amyloid; Amyloid Neuropathies; Blotting, Western; Dimerization; Electrophoresis, Polyacrylamide Gel; Female; Genetic Variation; Humans; Middle Aged; Myocardium; Prealbumin; Sciatic Nerve; Serine | 2003 |
Ser-64 and Ser-111 in PHAS-I are dispensable for insulin-stimulated dissociation from eIF4E.
Topics: Adaptor Proteins, Signal Transducing; Alanine; Binding Sites; Carrier Proteins; Cell Cycle Proteins; Cell Line; DNA, Complementary; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factors; Genetic Vectors; Humans; Insulin; Mutation; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Structure, Tertiary; Serine; Sirolimus; Threonine; Transfection | 2003 |
Genetic modulation of PPARgamma phosphorylation regulates insulin sensitivity.
Topics: Adiponectin; Adipose Tissue; Adipose Tissue, Brown; Alanine; Amino Acid Substitution; Animals; Blood Glucose; Blotting, Southern; Body Weight; Cell Size; Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Embryo, Mammalian; Fatty Acids, Nonesterified; Female; Gene Expression; Glucose; Glucose Tolerance Test; Immunoblotting; Insulin; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Obesity; Phosphorylation; Proteins; Receptors, Cytoplasmic and Nuclear; Serine; Time Factors; Transcription Factors | 2003 |
A "dock, lock, and latch" structural model for a staphylococcal adhesin binding to fibrinogen.
Topics: Adhesins, Bacterial; Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Bacterial Adhesion; Bacterial Proteins; Binding Sites; Conserved Sequence; Crystallography, X-Ray; Fibrinogen; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Protein Binding; Protein Structure, Tertiary; Serine; Staphylococcus epidermidis; Thrombin | 2003 |
Functional and biochemical analysis of Chlamydia trachomatis MurC, an enzyme displaying UDP-N-acetylmuramate:amino acid ligase activity.
Topics: Alanine; Bacterial Proteins; Chlamydia trachomatis; Culture Media; Escherichia coli; Genetic Complementation Test; Glycine; Kinetics; Mutation; Peptide Synthases; Serine | 2003 |
The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5.
Topics: Acetylglucosamine; Active Transport, Cell Nucleus; Alanine; Animals; Cell Differentiation; Cell Division; Cell Line; Cell Nucleus; CREB-Binding Protein; Cytoplasm; Dimerization; DNA-Binding Proteins; Epithelial Cells; Galactosyltransferases; Glycosylation; Growth Substances; Humans; Insecta; Interferons; Lectins; Ligands; Luciferases; Mass Spectrometry; Microscopy, Fluorescence; Milk Proteins; Mutation; Nuclear Proteins; Phosphorylation; Prolactin; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Serine; STAT5 Transcription Factor; Threonine; Trans-Activators; Transcription, Genetic; Transfection; Tumor Suppressor Proteins; Tyrosine | 2004 |
Role of His-16 in turnover of T4 pyrimidine dimer glycosylase.
Topics: Alanine; Aspartic Acid; Cell Survival; Cysteine; Dimerization; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Lysine; Models, Biological; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Phenotype; Plasmids; Serine; Time Factors; Ultraviolet Rays | 2004 |
Distribution and pharmacology of alanine-serine-cysteine transporter 1 (asc-1) in rodent brain.
Topics: Alanine; Amino Acid Transport System A; Amino Acid Transport System ASC; Amino Acid Transport System L; Amino Acid Transport System y+; Animals; beta-Alanine; Blotting, Western; Brain; Brain Chemistry; Cell Line; Cysteine; Dose-Response Relationship, Drug; Embryo, Mammalian; Fusion Regulatory Protein-1; Glycine; Humans; Immunohistochemistry; Kidney; Male; Mice; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Sodium; Synaptosomes; Transfection | 2003 |
Derivatized amino acids relevant to native peptide synthesis by chemical ligation and acyl transfer.
Topics: Acylation; Alanine; Amino Acids; Glycine; Ligation; Models, Chemical; Molecular Structure; Peptides; Serine | 2003 |
Enzymatic and molecular characteristics of the efficiency and specificity of exfoliative toxin cleavage of desmoglein 1.
Topics: Alanine; alpha-Macroglobulins; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Cadherins; Desmoglein 1; DNA, Complementary; Dogs; Enzyme Inhibitors; Glutamic Acid; Glycine; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Point Mutation; Polymerase Chain Reaction; Precipitin Tests; Protein Binding; Protein Sorting Signals; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Serine Proteinase Inhibitors; Staphylococcus aureus; Time Factors; Toxins, Biological | 2004 |
Receptor-controlled phosphorylation of alpha 1 soluble guanylyl cyclase enhances nitric oxide-dependent cyclic guanosine 5'-monophosphate production in pituitary cells.
Topics: Alanine; Amino Acid Substitution; Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dimerization; Enzyme Activation; Enzyme Inhibitors; Female; Growth Hormone-Releasing Hormone; Guanylate Cyclase; Neuropeptides; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland, Anterior; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Neuropeptide; Receptors, Pituitary Hormone-Regulating Hormone; Serine; Soluble Guanylyl Cyclase; Vasoactive Intestinal Peptide | 2004 |
Synergy between conserved ABC signature Ser residues in P-glycoprotein catalysis.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Amino Acid Motifs; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Beryllium; Binding Sites; Catalysis; Charcoal; Dimerization; Dithiothreitol; Dose-Response Relationship, Drug; Fluorides; Humans; Kinetics; Ligands; Lipids; Mice; Mutagenesis; Mutation; Pichia; Protein Binding; Protein Structure, Tertiary; Serine; Temperature; Time Factors; Vanadates | 2004 |
Hydrogen bonding alteration of Thr-204 in the complex between pharaonis phoborhodopsin and its transducer protein.
Topics: Alanine; Amino Acid Substitution; Archaeal Proteins; Carotenoids; Deuterium Oxide; Halorhodopsins; Hydrogen Bonding; Natronobacterium; Phenylalanine; Photoreceptors, Microbial; Sensory Rhodopsins; Serine; Spectroscopy, Fourier Transform Infrared; Threonine; Tyrosine | 2003 |
Identification of protein kinases responsible for phosphorylation of Epstein-Barr virus nuclear antigen leader protein at serine-35, which regulates its coactivator function.
Topics: Alanine; Amino Acid Substitution; Animals; CDC2 Protein Kinase; Cell Line; Cell Transformation, Viral; Enzyme Activation; Herpesvirus 4, Human; Mutation; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Spodoptera; Viral Proteins | 2003 |
p120 catenin associates with microtubules: inverse relationship between microtubule binding and Rho GTPase regulation.
Topics: Alanine; Amino Acid Motifs; Animals; Catenins; Cell Adhesion; Cell Adhesion Molecules; Cell Line, Tumor; Centrosome; COS Cells; Delta Catenin; Electroporation; Green Fluorescent Proteins; Humans; Immunohistochemistry; Luminescent Proteins; Mice; Microtubules; Mitosis; Mutation; NIH 3T3 Cells; Phenotype; Phosphoproteins; Plasmids; Point Mutation; Protein Binding; Protein Structure, Tertiary; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; Recombinant Fusion Proteins; rho GTP-Binding Proteins; Serine; Transfection | 2004 |
Functional characterization of Caenorhabditis elegans heteromeric amino acid transporters.
Topics: Alanine; Amino Acid Transport Systems; Amino Acid Transport Systems, Basic; Amino Acids; Animals; Biological Transport; Caenorhabditis elegans; Carrier Proteins; Cell Membrane; Conserved Sequence; Evolution, Molecular; Fusion Regulatory Protein 1, Heavy Chain; Gene Expression; Kinetics; Membrane Glycoproteins; Oocytes; Phylogeny; Serine; Transfection; Xenopus laevis | 2004 |
Residue Asp-189 controls both substrate binding and the monovalent cation specificity of thrombin.
Topics: Alanine; Allosteric Site; Asparagine; Aspartic Acid; Binding Sites; Cations; Dose-Response Relationship, Drug; Glutamine; Humans; Hydrolysis; Ions; Kinetics; Lithium; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Conformation; Rubidium; Serine; Sodium; Substrate Specificity; Thrombin; Trypsin | 2004 |
Specificity of the endonuclease activity of the baculovirus alkaline nuclease for single-stranded DNA.
Topics: Alanine; Amino Acid Motifs; Animals; Baculoviridae; DNA; DNA-Binding Proteins; DNA, Single-Stranded; DNA, Superhelical; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endonucleases; Ethidium; Genome, Viral; Hydrolysis; Insecta; Intercalating Agents; Ions; Magnesium; Manganese; Mutation; Phosphorylation; Plasmids; Ribonucleases; Serine; Time Factors; Viral Proteins | 2004 |
Mutation S363A in the human delta-opioid receptor selectively reduces down-regulation by a peptide agonist.
Topics: Alanine; Amino Acid Substitution; Benzamides; Down-Regulation; Enkephalin, D-Penicillamine (2,5)-; Humans; Mutation; Piperazines; Receptors, Opioid, delta; Serine | 2004 |
Antagonisms in the utilization of D-amino acids by lactic acid bacteria. II. Influence of DL-serine and glycine on the utilization of D-alanine.
Topics: Alanine; Amino Acids; Dietary Proteins; Fabaceae; Glycine; Lactic Acid; Lactobacillus; Serine | 1950 |
Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands.
Topics: Alanine; Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cycloserine; Databases as Topic; Escherichia coli; Excitatory Amino Acid Antagonists; Glycine; Humans; Hydrogen Bonding; Indoles; Kynurenic Acid; Ligands; Mice; Models, Chemical; Models, Molecular; Molecular Sequence Data; Potassium Channels; Proline; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sequence Homology, Amino Acid; Serine; Threonine; Tryptophan; Water | 2004 |
Role of active-site residues Thr81, Ser82, Thr85, Gln157, and Tyr158 in yeast cystathionine beta-synthase catalysis and reaction specificity.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Catalysis; Chromatography, Affinity; Cystathionine beta-Synthase; Glutamine; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Nickel; Phenylalanine; Pyruvic Acid; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity; Threonine; Tyrosine | 2004 |
Clathrin-mediated endocytosis of Na+,K+-ATPase in response to parathyroid hormone requires ERK-dependent phosphorylation of Ser-11 within the alpha1-subunit.
Topics: Alanine; Animals; Butadienes; Cattle; Cell Membrane; Clathrin; DNA, Complementary; Endocytosis; Endosomes; Kidney; Mitogen-Activated Protein Kinases; Mutation; Nitriles; Opossums; Parathyroid Hormone; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Structure, Tertiary; Protein Transport; Rats; Serine; Sodium-Potassium-Exchanging ATPase; Staurosporine; Time Factors; Transfection | 2004 |
A peptide that antagonizes TCR-mediated reactions with both syngeneic and allogeneic agonists: functional and structural aspects.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Cell Line; Cell Line, Tumor; Clone Cells; Crystallography, X-Ray; Cytotoxicity Tests, Immunologic; Female; H-2 Antigens; Histocompatibility Antigen H-2D; Isoantigens; Lysine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oligopeptides; Protein Binding; Receptors, Antigen, T-Cell; Serine; Structure-Activity Relationship | 2004 |
The C-terminal domain is the primary determinant of histone H1 binding to chromatin in vivo.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line, Tumor; Chromatin; Gene Deletion; Glutamic Acid; Green Fluorescent Proteins; Histones; Humans; Kinetics; Luminescent Proteins; Lysine; Mice; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Point Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Spectrometry, Fluorescence; Threonine; Time Factors; Transfection | 2004 |
Evidence that the C-terminus of the D1 polypeptide of photosystem II is ligated to the manganese ion that undergoes oxidation during the S1 to S2 transition: an isotope-edited FTIR study.
Topics: Alanine; Carbon; Carbon Isotopes; Carboxylic Acids; Cations, Divalent; Cyanobacteria; Glycine; Isotope Labeling; Ligands; Manganese; Mutagenesis, Site-Directed; Oxidation-Reduction; Peptide Fragments; Photolysis; Photosystem II Protein Complex; Serine; Spectroscopy, Fourier Transform Infrared | 2004 |
Characterization of recombinant mannan-binding lectin-associated serine protease (MASP)-3 suggests an activation mechanism different from that of MASP-1 and MASP-2.
Topics: Alanine; Amino Acid Substitution; Animals; Baculoviridae; Carrier Proteins; Complement Activation; Complement C1 Inactivator Proteins; Complement C1 Inhibitor Protein; Enzyme Activation; Ficolins; Humans; Lectins; Mannose-Binding Lectin; Mannose-Binding Lectins; Mannose-Binding Protein-Associated Serine Proteases; Recombinant Proteins; Serine; Serine Endopeptidases; Serpins; Spodoptera | 2004 |
Phosphorylated p40PHOX as a negative regulator of NADPH oxidase.
Topics: Alanine; Animals; Cell Separation; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Enzyme Inhibitors; Humans; Mutagenesis, Site-Directed; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Serine; Sodium Dodecyl Sulfate; Threonine | 2004 |
Rescue of protein splicing activity from a Magnetospirillum magnetotacticum intein-like element.
Topics: Alanine; Alternative Splicing; Catalysis; Cysteine; Magnetospirillum; Models, Genetic; Mutation; Phenylalanine; Polymorphism, Genetic; Protein Splicing; Protein Structure, Tertiary; RNA Splicing; Serine; Tyrosine | 2004 |
Ala226 to Gly and Ser189 to Asp mutations convert rat chymotrypsin B to a trypsin-like protease.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Benzamidines; Chymotrypsin; Chymotrypsinogen; Glycine; Kinetics; Molecular Sequence Data; Mutation; Peptide Hydrolases; Protein Conformation; Rats; Serine; Substrate Specificity; Trypsin; Trypsin Inhibitors | 2004 |
14-3-3 binds to and mediates phosphorylation of microtubule-associated tau protein by Ser9-phosphorylated glycogen synthase kinase 3beta in the brain.
Topics: 14-3-3 Proteins; Alanine; Animals; Brain; Cell Line; Cells, Cultured; Cloning, Molecular; DNA, Complementary; Glutathione; Glutathione Transferase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Microtubules; Mutation; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Rats; Serine; tau Proteins; Transfection; Tyrosine 3-Monooxygenase | 2004 |
3C-like proteinase from SARS coronavirus catalyzes substrate hydrolysis by a general base mechanism.
Topics: Alanine; Amino Acid Substitution; Catalysis; Colorimetry; Coronavirus 3C Proteases; Cysteine; Cysteine Endopeptidases; Deuterium Exchange Measurement; Endopeptidases; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Serine; Severe acute respiratory syndrome-related coronavirus; Solvents; Substrate Specificity; Temperature; Thermodynamics; Viral Proteins | 2004 |
Neurological proteins are not enriched for repetitive sequences.
Topics: Alanine; Algorithms; Animals; Codon; Conserved Sequence; Databases, Factual; Drosophila Proteins; Eukaryotic Cells; Evolution, Molecular; Genome; Histidine; Humans; Nerve Tissue; Peptides; Phosphotransferases; Proteins; Repetitive Sequences, Amino Acid; Sequence Homology, Amino Acid; Serine; Tandem Repeat Sequences | 2004 |
A conditional marker gene allowing both positive and negative selection in plants.
Topics: Alanine; Arabidopsis; Catalysis; D-Amino-Acid Oxidase; DNA; Dose-Response Relationship, Drug; Genetic Markers; Genetic Techniques; Genetic Vectors; Hemiterpenes; Isoleucine; Keto Acids; Oxygen; Plants; Plants, Genetically Modified; RNA; Serine; Transgenes; Valine | 2004 |
The stereospecificity and catalytic efficiency of the tryptophan synthase-catalysed exchange of the alpha-protons of amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Catalysis; Deuterium; Glycine Hydroxymethyltransferase; Hydrogen; Kinetics; Norleucine; Nuclear Magnetic Resonance, Biomolecular; Predictive Value of Tests; Protons; Serine; Stereoisomerism; Substrate Specificity; Tryptophan; Tryptophan Synthase; Valine | 2004 |
Tryptophan 621 and serine 667 residues of Daxx regulate its nuclear export during glucose deprivation.
Topics: Active Transport, Cell Nucleus; Alanine; Antibiotics, Antineoplastic; Binding Sites; Cell Line, Tumor; Exportin 1 Protein; Fatty Acids, Unsaturated; Genetic Vectors; Glucose; Humans; Immunoblotting; Karyopherins; Male; Models, Biological; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Prostatic Neoplasms; Protein Binding; Receptors, Cytoplasmic and Nuclear; Serine; Time Factors; Tryptophan | 2004 |
Functional analysis of Chinese hamster phosphatidylserine synthase 1 through systematic alanine mutagenesis.
Topics: Alanine; Amino Acids; Animals; CDPdiacylglycerol-Serine O-Phosphatidyltransferase; Cell Line; CHO Cells; Cricetinae; Cricetulus; Gene Expression Regulation, Enzymologic; Mutagenesis, Site-Directed; Serine | 2004 |
The protein kinase C signaling pathway regulates a molecular switch between transactivation and transrepression activity of the peroxisome proliferator-activated receptor alpha.
Topics: Alanine; Cell Line, Tumor; Enzyme Inhibitors; Fibrinogen; Gene Expression; Humans; Ligands; Mutagenesis, Site-Directed; Phosphorylation; PPAR alpha; Protein Kinase C; Repressor Proteins; RNA, Messenger; Serine; Signal Transduction; Transcriptional Activation | 2004 |
Evidence for a proton transfer network and a required persulfide-bond-forming cysteine residue in Ni-containing carbon monoxide dehydrogenases.
Topics: Alanine; Aldehyde Oxidoreductases; Asparagine; Bacterial Proteins; Biological Transport; Catalysis; Clostridium; Cysteine; Electron Spin Resonance Spectroscopy; Histidine; Lysine; Multienzyme Complexes; Mutagenesis, Site-Directed; Nickel; Protons; Serine; Sulfides | 2004 |
NMR and mutagenesis studies on the phosphorylation region of human cardiac troponin I.
Topics: Alanine; Arginine; Calcium; Humans; Macromolecular Substances; Mutagenesis, Site-Directed; Myocardium; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Protein Structure, Tertiary; Protons; Recombinant Proteins; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Troponin C; Troponin I | 2004 |
Hepatitis C virus glycoprotein E2 contains a membrane-proximal heptad repeat sequence that is essential for E1E2 glycoprotein heterodimerization and viral entry.
Topics: Alanine; Amino Acid Sequence; Animals; Blotting, Western; Cell Line; COS Cells; Dimerization; Genetic Vectors; Glycoproteins; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Precipitin Tests; Proline; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Serine; Transfection; Viral Envelope Proteins | 2004 |
Allele-specific loss of heterozygosity at the DAL-1/4.1B (EPB41L3) tumor-suppressor gene locus in the absence of mutation.
Topics: Adult; Alanine; Alleles; Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Chromosome Mapping; DNA Mutational Analysis; DNA, Neoplasm; Exons; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Genetic Markers; Genomic Imprinting; Humans; Introns; Loss of Heterozygosity; Lung Neoplasms; Membrane Proteins; Mice; Microfilament Proteins; Molecular Sequence Data; Mutation; Polymorphism, Single Nucleotide; Polymorphism, Single-Stranded Conformational; Proteins; Serine; Tumor Suppressor Proteins | 2004 |
Genetic interactions with C-terminal domain (CTD) kinases and the CTD of RNA Pol II suggest a role for ESS1 in transcription initiation and elongation in Saccharomyces cerevisiae.
Topics: Alanine; Alleles; Cell Proliferation; Diploidy; Gene Deletion; Genotype; Mutation; NIMA-Interacting Peptidylprolyl Isomerase; Peptides; Peptidylprolyl Isomerase; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; RNA Polymerase II; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Temperature; Time Factors; Transcription, Genetic | 2004 |
Adult-onset ataxia telangiectasia due to ATM 5762ins137 mutation homozygosity.
Topics: Adult; Alanine; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Blood Cells; Blotting, Western; Cell Cycle Proteins; Cell Line; Cerebellum; DNA Mutational Analysis; DNA-Binding Proteins; Glycine; Homozygote; Humans; Magnetic Resonance Imaging; Male; Phosphorylation; Point Mutation; Protein Serine-Threonine Kinases; Radiation Tolerance; RNA Splice Sites; Serine; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2004 |
Dynein light chain 1, a p21-activated kinase 1-interacting substrate, promotes cancerous phenotypes.
Topics: Alanine; Apoptosis; Blotting, Western; Breast Neoplasms; Carrier Proteins; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Drosophila Proteins; Dyneins; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Humans; Immunohistochemistry; Microscopy, Fluorescence; Mutation; Neoplasms; p21-Activated Kinases; Phenotype; Phosphorylation; Plasmids; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Serine; Signal Transduction; Time Factors; Two-Hybrid System Techniques; Up-Regulation | 2004 |
Role of cysteine residues in the NCKX2 Na+/Ca(2+)-K+ Exchanger: generation of a functional cysteine-free exchanger.
Topics: Alanine; Amino Acid Sequence; Cell Line; Cysteine; Humans; Molecular Sequence Data; Mutagenesis; Precipitin Tests; Retinal Cone Photoreceptor Cells; Serine; Sodium-Calcium Exchanger; Spectrometry, Fluorescence | 2004 |
A novel pathway of epithelial sodium channel activation involves a serum- and glucocorticoid-inducible kinase consensus motif in the C terminus of the channel's alpha-subunit.
Topics: Alanine; Amiloride; Amino Acid Motifs; Animals; Cytosol; DNA, Complementary; Enzyme Activation; Epithelial Sodium Channels; Gene Deletion; Immediate-Early Proteins; Magnesium; Models, Biological; Mutagenesis, Site-Directed; Nuclear Proteins; Oocytes; Patch-Clamp Techniques; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Rats; Recombinant Proteins; RNA, Complementary; Serine; Sodium Channels; Time Factors; Xenopus; Xenopus laevis | 2004 |
Calcium/calmodulin-dependent protein kinase I inhibits neuronal nitric-oxide synthase activity through serine 741 phosphorylation.
Topics: Alanine; Animals; Antibodies, Monoclonal; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; DNA, Complementary; Humans; Insecta; Mutation; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phosphorylation; Plasmids; Rats; Recombinant Proteins; Serine; Transfection | 2004 |
Dynamin GTPase domain mutants that differentially affect GTP binding, GTP hydrolysis, and clathrin-mediated endocytosis.
Topics: Adenoviridae; Alanine; Baculoviridae; Binding Sites; Chromatography, Gel; Clathrin; Dynamins; Endocytosis; GTP Phosphohydrolases; Guanosine Triphosphate; Humans; Hydrolysis; Kinetics; Lipids; Models, Chemical; Mutation; Oligonucleotides; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serine; Temperature; Threonine; Time Factors; Transferrin | 2004 |
The fourth transmembrane domain of the Helicobacter pylori Na+/H+ antiporter NhaA faces a water-filled channel required for ion transport.
Topics: Alanine; Amino Acid Sequence; Antiporters; Aspartic Acid; Binding Sites; Cell Membrane; Cysteine; Cytoplasm; DNA; Escherichia coli; Escherichia coli Proteins; Ethylmaleimide; Helicobacter pylori; Ion Transport; Ions; Kinetics; Leucine; Lithium; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protons; Serine; Sodium-Hydrogen Exchangers; Threonine; Valine; Water | 2004 |
Serine and threonine phosphorylation of the low density lipoprotein receptor-related protein by protein kinase Calpha regulates endocytosis and association with adaptor molecules.
Topics: Adaptor Proteins, Signal Transducing; Alanine; Animals; Cell Line; CHO Cells; COS Cells; Cricetinae; Cytoplasm; DNA Mutational Analysis; Dose-Response Relationship, Drug; Endocytosis; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Glutathione Transferase; Humans; Immunoblotting; Ligands; Low Density Lipoprotein Receptor-Related Protein-1; Mutation; Phosphoamino Acids; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Protein Structure, Tertiary; Proteins; Rats; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Signal Transduction; Threonine; Time Factors; Transfection | 2004 |
Mutational analysis of protein splicing, cleavage, and self-association reactions mediated by the naturally split Ssp DnaE intein.
Topics: Alanine; Amino Acid Substitution; Binding, Competitive; Cyanobacteria; DNA Mutational Analysis; DNA Polymerase III; Histidine; Hydrolysis; Peptide Fragments; Protein Binding; Protein Splicing; Recombinant Fusion Proteins; Serine | 2004 |
Regulating the balance between peroxisome proliferator-activated receptor gamma and beta-catenin signaling during adipogenesis. A glycogen synthase kinase 3beta phosphorylation-defective mutant of beta-catenin inhibits expression of a subset of adipogenic
Topics: Adipocytes; Alanine; Animals; Azo Compounds; beta Catenin; Blotting, Western; CCAAT-Enhancer-Binding Protein-alpha; Cell Differentiation; Cell Line; Chromans; Coloring Agents; Cytoskeletal Proteins; Fibroblasts; Genes, Reporter; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Lipids; Luciferases; Mice; Mutation; Phosphorylation; Plasmids; PPAR gamma; Response Elements; RNA; Serine; Signal Transduction; Thiazolidinediones; Trans-Activators; Transcriptional Activation; Troglitazone | 2004 |
The effect of sugar, amino acid, metal ion, and NaCl on model Maillard reaction under pH control.
Topics: Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Biochemistry; Carbohydrates; Colorimetry; Copper; Cysteine; Fructose; Glucose; Glutamic Acid; Glycine max; Hot Temperature; Hydrogen-Ion Concentration; Ions; Iron; Isoleucine; Leucine; Lysine; Maltose; Metals; Models, Chemical; Phenylalanine; Proline; Serine; Sodium Chloride; Temperature; Time Factors; Valine; Xylose | 2004 |
Metabolic properties of Eubacterium pyruvativorans, a ruminal 'hyper-ammonia-producing' anaerobe with metabolic properties analogous to those of Clostridium kluyveri.
Topics: Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; Caseins; Clostridium; Crotonates; Energy Metabolism; Eubacterium; Fatty Acids, Volatile; Fermentation; Glycine; Lactic Acid; Leucine; Peptides; Proline; Pyruvic Acid; Rumen; Serine; Threonine | 2004 |
[Significance of serum calcium levels in colorectal cancer].
Topics: Aged; Alanine; Biomarkers, Tumor; CA-19-9 Antigen; Calcium; Colorectal Neoplasms; Female; Genotype; Humans; Male; Middle Aged; Polymorphism, Genetic; Predictive Value of Tests; Prognosis; Receptors, Calcium-Sensing; Risk Factors; Serine | 2004 |
The vaccinia virus B1R kinase induces p53 downregulation by an Mdm2-dependent mechanism.
Topics: Alanine; Amino Acid Substitution; Animals; Cell Line; Down-Regulation; Mice; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Serine; Threonine; Tumor Suppressor Protein p53; Vaccinia virus; Viral Proteins | 2004 |
CK2 is responsible for phosphorylation of human La protein serine-366 and can modulate rpL37 5'-terminal oligopyrimidine mRNA metabolism.
Topics: Alanine; Apoptosis; Autoantigens; Casein Kinase II; Cell Line; Humans; Mutation; Phosphorylation; Phosphoserine; Polyribosomes; Protein Processing, Post-Translational; Pyrimidines; Ribonucleoproteins; Ribosomal Proteins; RNA, Messenger; Serine; SS-B Antigen; Triazoles | 2004 |
Inhibitor-resistant class A beta-lactamases: consequences of the Ser130-to-Gly mutation seen in Apo and tazobactam structures of the SHV-1 variant.
Topics: Alanine; Amino Acid Substitution; Apoenzymes; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Catalysis; Crystallography, X-Ray; Enzyme Inhibitors; Escherichia coli Proteins; Genetic Variation; Glutamic Acid; Glycine; Hydrolysis; Models, Molecular; Mutagenesis, Site-Directed; Penicillanic Acid; Serine; Tazobactam | 2004 |
Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA).
Topics: Alanine; Amidines; Benzimidazoles; Binding Sites; Crystallography, X-Ray; Drug Design; Guanidine; Humans; Hydrogen Bonding; Indoles; Molecular Structure; Mutagenesis, Site-Directed; Mutation; Protease Inhibitors; Protein Binding; Serine; Structure-Activity Relationship; Substrate Specificity; Thermodynamics; Urokinase-Type Plasminogen Activator; Water | 2004 |
Phosphorylation of Cdc25C by pp90Rsk contributes to a G2 cell cycle arrest in Xenopus cycling egg extracts.
Topics: 14-3-3 Proteins; Alanine; Animals; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Extracts; Enzyme Activation; Female; G2 Phase; Gene Expression Regulation, Enzymologic; Immunoprecipitation; Mitogen-Activated Protein Kinase 1; Oocytes; Phosphorylation; Protein Binding; Recombinant Proteins; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Xenopus; Xenopus Proteins | 2005 |
Molecular functions of conserved aspects of the GHMP kinase family.
Topics: Alanine; Amino Acid Motifs; Amino Acid Substitution; Aspartic Acid; Binding Sites; Brain Diseases, Metabolic, Inborn; Catalytic Domain; Conserved Sequence; Humans; Kinetics; Lysine; Mevalonic Acid; Models, Molecular; Multigene Family; Phosphotransferases (Phosphate Group Acceptor); Protein Structure, Secondary; Serine; Streptococcus pneumoniae; Substrate Specificity | 2004 |
Ycf1-dependent cadmium detoxification by yeast requires phosphorylation of residues Ser908 and Thr911.
Topics: Alanine; Alkaline Phosphatase; Amino Acid Substitution; ATP-Binding Cassette Transporters; Cadmium; Electrophoretic Mobility Shift Assay; Fungal Proteins; Gene Deletion; Inactivation, Metabolic; Phosphorylation; Point Mutation; Protein Kinases; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine | 2004 |
A CRM1-dependent nuclear export pathway is involved in the regulation of IRF-5 subcellular localization.
Topics: Active Transport, Cell Nucleus; Alanine; Amino Acid Sequence; Blotting, Western; Cell Line; Cell Nucleus; Cytoplasm; DNA Mutational Analysis; DNA-Binding Proteins; Exportin 1 Protein; Genes, Reporter; Green Fluorescent Proteins; Humans; Immunoblotting; Interferon Regulatory Factors; Interferons; Karyopherins; Leucine; Luciferases; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Phosphorylation; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Sequence Homology, Amino Acid; Serine; Threonine; Time Factors; Transcription Factors; Transfection | 2005 |
Phosphorylation of progesterone receptor serine 400 mediates ligand-independent transcriptional activity in response to activation of cyclin-dependent protein kinase 2.
Topics: Alanine; Amino Acid Substitution; Animals; Blotting, Western; Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Line, Tumor; Cells, Cultured; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Down-Regulation; Embryo, Mammalian; Enzyme Activation; Fibroblasts; Gene Deletion; HeLa Cells; Humans; Ligands; Mice; Mitogens; Phosphorylation; Progestins; Protein Isoforms; Receptors, Progesterone; RNA Interference; Serine; Transcription, Genetic; Tumor Suppressor Proteins | 2004 |
Cysteine-scanning mutagenesis of muscle carnitine palmitoyltransferase I reveals a single cysteine residue (Cys-305) is important for catalysis.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Carnitine; Carnitine O-Palmitoyltransferase; Catalysis; Cysteine; DNA Primers; Humans; Kinetics; Malonyl Coenzyme A; Models, Chemical; Molecular Sequence Data; Mutagenesis; Mutation; Myocardium; Palmitic Acid; Palmitoylcarnitine; Pichia; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine | 2005 |
Substrate-trapping techniques in the identification of cellular PTP targets.
Topics: Alanine; Aspartic Acid; Catalytic Domain; Cysteine; Glutathione; Mutation; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; Serine; Substrate Specificity; Vanadates | 2005 |
Side chain orientation of residues lining the selectivity filter of epithelial Na+ channels.
Topics: Alanine; Amiloride; Amino Acid Sequence; Animals; Binding Sites; Cadmium; Cations; Cysteine; Dithiothreitol; Dose-Response Relationship, Drug; Electrophysiology; Epithelial Sodium Channels; Mice; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oocytes; Protein Binding; Protein Structure, Tertiary; RNA, Complementary; Sequence Homology, Amino Acid; Serine; Sodium Channels; Time Factors; Xenopus | 2005 |
Identification of a membrane-localized cysteine cluster near the substrate-binding sites of the Streptococcus equisimilis hyaluronan synthase.
Topics: Alanine; Binding Sites; Carbon Isotopes; Cell Membrane; Cysteine; Glucuronosyltransferase; Hyaluronan Synthases; Isotope Labeling; Models, Molecular; Mutagenesis, Site-Directed; Point Mutation; Protein Binding; Serine; Streptococcus equi; Structure-Activity Relationship | 2005 |
Cellular stability of serotonin N-acetyltransferase conferred by phosphonodifluoromethylene alanine (Pfa) substitution for Ser-205.
Topics: 14-3-3 Proteins; Alanine; Amino Acids; Animals; Arylalkylamine N-Acetyltransferase; CHO Cells; Cloning, Molecular; Cricetinae; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Hydrocarbons; Immunohistochemistry; Kinetics; Mass Spectrometry; Melatonin; Methane; Models, Biological; Models, Chemical; Organophosphonates; Peptides; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteins; Serine; Sheep | 2005 |
DNA binding of repressor nuclear factor-kappaB p50/p50 depends on phosphorylation of Ser337 by the protein kinase A catalytic subunit.
Topics: Alanine; Animals; Catalytic Domain; Cell Line; Cell Nucleus; Chromatography, Gel; COS Cells; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Dimerization; DNA; Enzyme Inhibitors; HeLa Cells; Humans; Immunoblotting; Immunoprecipitation; NF-kappa B p50 Subunit; Peptides; Phosphorylation; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Serine; Transcription Factors; Transfection; Tumor Necrosis Factor-alpha | 2005 |
Association of Ala72Ser polymorphism with COMT enzyme activity and the risk of schizophrenia in Koreans.
Topics: Alanine; Base Sequence; Catechol O-Methyltransferase; DNA Primers; Genetic Predisposition to Disease; Haplotypes; Humans; Korea; Polymorphism, Single Nucleotide; Schizophrenia; Serine | 2005 |
Identification of residues that contribute to receptor activation through the analysis of compensatory mutations in the G protein-coupled alpha-factor receptor.
Topics: Alanine; Amino Acid Sequence; Cysteine; DNA Mutational Analysis; Genes, Suppressor; Genetic Testing; Mating Factor; Molecular Sequence Data; Mutagenesis; Peptides; Phenylalanine; Receptors, G-Protein-Coupled; Receptors, Mating Factor; Receptors, Peptide; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Threonine; Transcription Factors; Tyrosine | 2005 |
Investigation of the functional contributions of invariant serine residues in yeast mevalonate diphosphate decarboxylase.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Carboxy-Lyases; Enzyme Stability; Fluorescent Dyes; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphotransferases; Protein Folding; Protein Subunits; Saccharomyces cerevisiae Proteins; Serine; Spectrometry, Fluorescence; Substrate Specificity | 2005 |
Palmitoylated cysteine 192 is required for RhoB tumor-suppressive and apoptotic activities.
Topics: Alanine; Amino Acid Sequence; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cysteine; DNA Primers; Genes, Tumor Suppressor; Glycine; Humans; In Situ Nick-End Labeling; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Palmitic Acid; Promoter Regions, Genetic; Protein Biosynthesis; Protein Prenylation; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; Sequence Homology, Amino Acid; Serine; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transforming Growth Factor beta | 2005 |
Phosphorylation-dependent binding of 14-3-3 to Par3beta, a human Par3-related cell polarity protein.
Topics: 14-3-3 Proteins; Alanine; Alkaline Phosphatase; Amino Acid Sequence; Animals; Binding Sites; Body Patterning; Carrier Proteins; Cattle; Cell Line; Cell Lineage; COS Cells; DNA, Complementary; Dogs; Epithelial Cells; Gene Library; HeLa Cells; Humans; Immunoprecipitation; Intestines; Membrane Proteins; Models, Genetic; Molecular Sequence Data; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Structure, Tertiary; Receptors, Thrombin; Sequence Homology, Amino Acid; Serine; Two-Hybrid System Techniques | 2005 |
Crystal structure of S-ribosylhomocysteinase (LuxS) in complex with a catalytic 2-ketone intermediate.
Topics: Alanine; Arginine; Bacillus subtilis; Bacterial Proteins; Binding Sites; Carbon-Sulfur Lyases; Catalysis; Cobalt; Crystallization; Crystallography, X-Ray; Cysteine; Ferrous Compounds; Histidine; Homocysteine; Hydrolases; Ketones; Models, Molecular; Mutagenesis, Site-Directed; Serine; Spectrophotometry, Ultraviolet; Substrate Specificity; Vibrio | 2005 |
A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad.
Topics: Alanine; Apoptosis; bcl-Associated Death Protein; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Cell Line, Tumor; Cell Survival; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Inhibitors; HeLa Cells; HL-60 Cells; Humans; Intracellular Fluid; Phosphorylation; Protein Structure, Tertiary; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Recombinant Fusion Proteins; Serine; U937 Cells | 2005 |
Changes in tissue protein synthesis are involved in regulating urea synthesis in rats given proteins of different quality.
Topics: Alanine; Amino Acids; Ammonia; Animals; Caseins; Dietary Proteins; Egg Proteins; Glutamic Acid; Glutens; Homeostasis; Kinetics; Liver; Male; Protein Biosynthesis; Rats; Serine; Urea | 2004 |
Identification and functional characterization of a novel low affinity aromatic-preferring amino acid transporter (arpAT). One of the few proteins silenced during primate evolution.
Topics: Alanine; Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Amino Acids; Amino Acids, Aromatic; Animals; Arginine; Biological Transport; Blotting, Northern; Blotting, Western; Cell Lineage; Chickens; Cloning, Molecular; Cysteine; Dimerization; DNA, Complementary; Dogs; Dose-Response Relationship, Drug; Evolution, Molecular; Gene Library; Gene Silencing; Glutamine; Glycine; HeLa Cells; Humans; In Situ Hybridization; Inhibitory Concentration 50; Intestine, Small; Kidney; Kinetics; Levodopa; Mice; Molecular Sequence Data; Open Reading Frames; Pan troglodytes; Phylogeny; Proline; Protein Binding; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Sodium; Transfection | 2005 |
Serine 16 phosphorylation induces an order-to-disorder transition in monomeric phospholamban.
Topics: Alanine; Amino Acid Sequence; Calcium-Binding Proteins; Calcium-Transporting ATPases; Cysteine; Enzyme Inhibitors; Molecular Sequence Data; Mutation; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphorylation; Protein Conformation; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine; Solutions; Structure-Activity Relationship; Thermodynamics | 2005 |
Abrogation of fibroblast activation protein enzymatic activity attenuates tumor growth.
Topics: Alanine; Animals; Antigens, Neoplasm; Antineoplastic Agents; Binding Sites; Biomarkers, Tumor; Blotting, Western; Catalytic Domain; Cell Line; Cell Line, Tumor; Cell Proliferation; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; DNA, Complementary; Endopeptidases; Fibroblasts; Flow Cytometry; Gelatinases; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Kinetics; Membrane Proteins; Mice; Microscopy, Fluorescence; Models, Molecular; Neoplasm Transplantation; Neoplasms; Serine; Serine Endopeptidases; Time Factors; Transfection | 2005 |
The structure of Apo R268A human aldose reductase: hinges and latches that control the kinetic mechanism.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); Alanine; Aldehyde Reductase; Arginine; Base Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; Glycine; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; NADP; Protein Conformation; Serine; Static Electricity; Stereoisomerism; Temperature; Ultraviolet Rays | 2005 |
Heterologous expression, purification, crystallization, X-ray analysis and phasing of the acetyl xylan esterase from Bacillus pumilus.
Topics: Acetylesterase; Alanine; Bacillus; Carbohydrate Conformation; Carbohydrate Sequence; Carbohydrates; Catalysis; Cell Wall; Cephalosporins; Chromatography, Gel; Crystallography, X-Ray; Escherichia coli; Esterases; Light; Lithium Chloride; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Recombinant Proteins; Scattering, Radiation; Serine; Time Factors; X-Ray Diffraction; Xylans; Xylose | 2005 |
A novel assay method for an amino acid racemase reaction based on circular dichroism.
Topics: Alanine; Alanine Racemase; Circular Dichroism; Escherichia coli; Kinetics; Serine; Streptomyces | 2005 |
p38 Mitogen-activated protein kinase (MAPK) is a key mediator in glucocorticoid-induced apoptosis of lymphoid cells: correlation between p38 MAPK activation and site-specific phosphorylation of the human glucocorticoid receptor at serine 211.
Topics: Alanine; Animals; Apoptosis; Cell Line; Cell Line, Tumor; Cell Survival; Dexamethasone; DNA; Enzyme Activation; Flow Cytometry; Glucocorticoids; Humans; Immunohistochemistry; Kinetics; Lymphocytes; MAP Kinase Kinase 3; MAP Kinase Signaling System; Mice; Models, Biological; Mutation; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Propidium; Proto-Oncogene Proteins c-myc; Receptors, Glucocorticoid; RNA, Messenger; Serine; Signal Transduction; Threonine; Time Factors; Transcriptional Activation; Transfection | 2005 |
Substitution of the cysteine 438 residue in the cytoplasmic tail of the glucagon-like peptide-1 receptor alters signal transduction activity.
Topics: Adenylyl Cyclases; Alanine; Animals; CHO Cells; Consensus Sequence; Cricetinae; Cyclic AMP; Cysteine; Cytoplasm; Endocytosis; Female; Glucagon-Like Peptide-1 Receptor; GTP-Binding Proteins; Mutagenesis, Site-Directed; Mutation; Palmitates; Protein Kinase C; Rats; Receptors, Glucagon; Serine; Signal Transduction; Transfection | 2005 |
Computationally designed variants of Escherichia coli chorismate mutase show altered catalytic activity.
Topics: Alanine; Amino Acid Substitution; Catalysis; Catalytic Domain; Chorismate Mutase; Computational Biology; Escherichia coli; Mutation; Protein Engineering; Serine | 2005 |
Protein kinase A mediates regulation of gap junctions containing connexin35 through a complex pathway.
Topics: Alanine; Amino Acid Sequence; Animals; Connexins; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gap Junctions; Gene Expression Regulation; HeLa Cells; Humans; Immunohistochemistry; Mice; Models, Biological; Mutagenesis; Mutation; Perches; Phosphorylation; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Serine; Skates, Fish; Transfection | 2005 |
Point mutations at the type I Cu ligands, Cys457 and Met467, and at the putative proton donor, Asp105, in Myrothecium verrucaria bilirubin oxidase and reactions with dioxygen.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Copper; Cysteine; Dithionite; Fungal Proteins; Glutamic Acid; Glutamine; Hypocreales; Ligands; Methionine; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Point Mutation; Protons; Serine | 2005 |
Residues stabilizing the heme moiety of the nitric oxide sensor soluble guanylate cyclase.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Benzoates; Binding Sites; CHO Cells; Cricetinae; Cricetulus; Cyclic GMP; Diethylamines; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Genotype; Guanylate Cyclase; Heme; Molecular Sequence Data; Mutation, Missense; Nitric Acid; Nitrogen Oxides; Oxadiazoles; Protoporphyrins; Pyrazoles; Pyridines; Quinoxalines; Sequence Homology, Amino Acid; Serine; Solubility; Transfection | 2005 |
Effects of Ser2 and Tyr6 mutants of BAF53 on cell growth and p53-dependent transcription.
Topics: Actins; Adaptor Proteins, Signal Transducing; Alanine; Cell Proliferation; Cells, Cultured; Chromatin; Chromosomal Proteins, Non-Histone; DNA-Binding Proteins; Humans; Kidney; Mutation; Nuclear Proteins; Promoter Regions, Genetic; Serine; Transcription Factors; Transcription, Genetic; Tumor Suppressor Protein p53; Tyrosine | 2005 |
Mechanism of zinc coordination by point-mutated structures of the distal CCHC binding motif of the HIV-1 NCp7 protein.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Capsid Proteins; Cysteine; gag Gene Products, Human Immunodeficiency Virus; Gene Products, gag; Histidine; HIV-1; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Molecular Sequence Data; Peptide Fragments; Point Mutation; Protein Binding; Serine; Spectrometry, Fluorescence; Viral Proteins; Zinc | 2005 |
No association between the ionotropic glutamate receptor kainate 3 gene ser310ala polymorphism and schizophrenia.
Topics: Adult; Alanine; DNA Mutational Analysis; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Polymorphism, Genetic; Receptors, AMPA; Receptors, Glutamate; Schizophrenia; Serine | 2005 |
Critical hydrophobic interactions between phosphorylation and actuator domains of Ca2+-ATPase for hydrolysis of phosphorylated intermediate.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Animals; Calcium; Calcium-Transporting ATPases; Catalytic Domain; Crystallography, X-Ray; Hydrolysis; Isoleucine; Kinetics; Leucine; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Phosphates; Phosphorylation; Potassium; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rabbits; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine; Temperature; Time Factors; Tyrosine | 2005 |
BAD detects coincidence of G2/M phase and growth factor deprivation to regulate apoptosis.
Topics: 14-3-3 Proteins; Alanine; Animals; Apoptosis; Bacterial Proteins; bcl-Associated Death Protein; Blotting, Western; Carrier Proteins; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Proliferation; DNA, Complementary; Dose-Response Relationship, Drug; Escherichia coli; Flow Cytometry; Fluorescence Resonance Energy Transfer; G1 Phase; G2 Phase; Gene Library; Green Fluorescent Proteins; Growth Substances; Humans; Immunoblotting; Immunoprecipitation; Interleukin-3; Luminescent Proteins; Lymphocytes; Membrane Potentials; Mice; Mitochondria; Models, Biological; Mutation; NIH 3T3 Cells; Nocodazole; Phosphorylation; Plasmids; Point Mutation; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; RNA Interference; Serine; Spectrometry, Fluorescence; Surface Plasmon Resonance; Time Factors | 2005 |
Phosphorylation of the yeast choline kinase by protein kinase C. Identification of Ser25 and Ser30 as major sites of phosphorylation.
Topics: Adenosine Triphosphate; Alanine; Alleles; Amino Acid Motifs; Binding Sites; Biochemical Phenomena; Biochemistry; Choline Kinase; Cyclic AMP-Dependent Protein Kinases; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrolysis; Immunoblotting; Immunoglobulin G; Immunoprecipitation; Kinetics; Models, Biological; Mutation; Peptide Mapping; Peptides; Phosphatidylcholines; Phosphorylation; Plasmids; Polymerase Chain Reaction; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Saccharomyces cerevisiae; Serine; Substrate Specificity; Time Factors | 2005 |
Phosphorylation of the RGS protein Sst2 by the MAP kinase Fus3 and use of Sst2 as a model to analyze determinants of substrate sequence specificity.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Consensus Sequence; Feedback, Physiological; GTPase-Activating Proteins; Histidine; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phenylalanine; Phosphorylation; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity; Tryptophan | 2005 |
The crystal structure of Mlc, a global regulator of sugar metabolism in Escherichia coli.
Topics: Alanine; Arthrobacter; Bacillus subtilis; beta-Galactosidase; Binding Sites; Carbohydrate Metabolism; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Databases, Protein; Dimerization; Escherichia coli; Escherichia coli Proteins; Fructokinases; Glucokinase; Glucose; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Repressor Proteins; Serine; Transcription, Genetic; Zinc | 2005 |
N-terminal acetylation and protonation of individual hemoglobin subunits: position-dependent effects on tetramer strength and cooperativity.
Topics: Acetylation; Alanine; Amino Acid Substitution; Hemoglobin A; Humans; Oxygen; Protein Structure, Quaternary; Protons; Serine | 2005 |
D-Serine uptake by isolated retinas is consistent with ASCT-mediated transport.
Topics: 4-Chloro-7-nitrobenzofurazan; Alanine; Ambystoma; Amino Acid Transport System ASC; Animals; Biological Transport; Cysteine; Electrophoresis, Capillary; In Vitro Techniques; Retina; Serine; Sodium; Threonine; Time Factors | 2005 |
Identification of Ser153 in ICL2 of the gonadotropin-releasing hormone (GnRH) receptor as a phosphorylation-independent site for inhibition of Gq coupling.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; COS Cells; DNA Primers; Epitopes; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gq-G11; Hydrolysis; Immunoblotting; Inositol Phosphates; Kinetics; MAP Kinase Signaling System; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Phosphorylation; Plasmids; Polymerase Chain Reaction; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; Receptors, LHRH; Serine; Threonine; Time Factors; Transfection | 2005 |
Protein kinase A-dependent phosphorylation of Lutheran/basal cell adhesion molecule glycoprotein regulates cell adhesion to laminin alpha5.
Topics: Adrenergic beta-Antagonists; Alanine; Amino Acid Sequence; Anemia, Sickle Cell; Animals; Blotting, Western; Butoxamine; Casein Kinase II; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Dogs; Epinephrine; Epithelial Cells; Erythrocytes; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Glycoproteins; Humans; Immunoprecipitation; K562 Cells; Kidney; Laminin; Lutheran Blood-Group System; Molecular Sequence Data; Mutation; Neoplasm Proteins; Phosphorylation; Protein Structure, Tertiary; Recombinant Proteins; Serine; Signal Transduction; Up-Regulation | 2005 |
Mutation of the adenylylated tyrosine of glutamine synthetase alters its catalytic properties.
Topics: Adenine; Adenosine Diphosphate; Adenosine Monophosphate; Alanine; Catalysis; Cations, Divalent; Enzyme Activation; Escherichia coli Proteins; Esterification; Feedback, Physiological; gamma-Glutamyltransferase; Glutamate-Ammonia Ligase; Glutamine; Hydrogen-Ion Concentration; Hydroxides; Magnesium; Manganese; Mutagenesis, Site-Directed; Phenylalanine; Serine; Tyrosine | 2005 |
Sequential phosphorylation mediates receptor- and kinase-induced inhibition of TREK-1 background potassium channels.
Topics: Alanine; Animals; Aspartic Acid; Binding Sites; Blotting, Western; Cell Line; Cell Membrane; Cloning, Molecular; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Humans; Indoles; Maleimides; Mice; Models, Biological; Mutagenesis, Site-Directed; Mutation; Orexin Receptors; Phorbol 12,13-Dibutyrate; Phosphorylation; Potassium; Potassium Channels; Potassium Channels, Tandem Pore Domain; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Receptors, Thyrotropin-Releasing Hormone; Recombinant Proteins; Serine; Time Factors; Transfection | 2005 |
Stereoselective synthesis of alpha-C-glucosyl serine and alanine via a cross-metathesis/cyclization strategy.
Topics: Alanine; Catalysis; Cyclization; Glycoproteins; Mercury; Molecular Structure; Serine; Stereoisomerism | 2005 |
Dephosphorylation of Ser-226 facilitates plasma membrane retention of Ntcp.
Topics: Alanine; Amino Acid Substitution; Animals; Autoradiography; Binding Sites; Cell Line; Cell Line, Tumor; Cell Membrane; Cyclic AMP; Cysteine Endopeptidases; Electrophoresis, Polyacrylamide Gel; Hepatocytes; Humans; Membrane Transport Proteins; Molecular Weight; Organic Anion Transporters, Sodium-Dependent; Peptide Fragments; Phosphorus Radioisotopes; Point Mutation; Protein Structure, Secondary; Protein Transport; Rats; Serine; Symporters; Taurocholic Acid; Transfection | 2005 |
Phosphorylation of the homeotic tumor suppressor Cdx2 mediates its ubiquitin-dependent proteasome degradation.
Topics: Adenocarcinoma; Alanine; Alkaline Phosphatase; Amino Acid Sequence; Amino Acid Substitution; Animals; Caco-2 Cells; CDX2 Transcription Factor; Chlorocebus aethiops; Colonic Neoplasms; Consensus Sequence; Conserved Sequence; COS Cells; Cyclin-Dependent Kinase 2; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glycine; Homeodomain Proteins; Humans; Intestinal Mucosa; Jejunum; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Sequence Homology, Amino Acid; Serine; Transcription Factors; Transcription, Genetic; Ubiquitin | 2005 |
Structure of the wild-type TEM-1 beta-lactamase at 1.55 A and the mutant enzyme Ser70Ala at 2.1 A suggest the mode of noncovalent catalysis for the mutant enzyme.
Topics: Alanine; beta-Lactamases; Binding Sites; Catalysis; Crystallography, X-Ray; Escherichia coli; Kinetics; Mutagenesis, Site-Directed; Serine; Staphylococcus aureus | 2005 |
Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance.
Topics: Alanine; Amino Acid Sequence; Animals; Blotting, Northern; Blotting, Western; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; COS Cells; Cyclin-Dependent Kinase Inhibitor p21; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Glutathione Transferase; Glycogen Synthase Kinase 3; Humans; Immunoprecipitation; Mice; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Nuclear Proteins; Peptides; Phosphorylation; Plasmids; Proteasome Endopeptidase Complex; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Radiation, Ionizing; Reverse Transcriptase Polymerase Chain Reaction; RNA; Serine; Time Factors; Transfection; Tumor Suppressor Protein p53; Ubiquitin | 2005 |
Identification of factor Xa residues critical for interaction with protein Z-dependent protease inhibitor: both active site and exosite interactions are required for inhibition.
Topics: Alanine; Animals; Arginine; Binding Sites; Binding, Competitive; Catalysis; Cell Line; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Factor Xa; Heparin; Humans; Kinetics; Lipoproteins; Lysine; Models, Biological; Mutagenesis; Mutation; Phospholipids; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Serine; Serpins | 2005 |
Structural and mutational analyses of the molecular interactions between the catalytic domain of factor XIa and the Kunitz protease inhibitor domain of protease nexin 2.
Topics: Alanine; Alzheimer Disease; Arginine; Binding Sites; Carrier Proteins; Catalytic Domain; Crystallography, X-Ray; Disulfides; DNA Mutational Analysis; Dose-Response Relationship, Drug; Factor XIa; Humans; Inhibitory Concentration 50; Kinetics; Lysine; Models, Molecular; Models, Statistical; Mutation; Partial Thromboplastin Time; Phenylalanine; Plasmids; Point Mutation; Proline; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Serine; Serine Proteinase Inhibitors; Structure-Activity Relationship; Thromboplastin; Time Factors; Vesicular Transport Proteins | 2005 |
Molecular basis of alanine discrimination in editing site.
Topics: Acylation; Alanine; Amino Acid Sequence; Amino Acyl-tRNA Synthetases; Apoenzymes; Bacterial Proteins; Binding Sites; Dimerization; Humans; Models, Molecular; Molecular Sequence Data; Protein Structure, Quaternary; Pyrococcus horikoshii; RNA Editing; RNA, Transfer, Ala; Sequence Alignment; Serine; Substrate Specificity; Threonine; Zinc | 2005 |
Structure and function of lysosomal phospholipase A2: identification of the catalytic triad and the role of cysteine residues.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Brain; Catalysis; Catalytic Domain; Cattle; Chlorocebus aethiops; Chromatography; COS Cells; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Histidine; Humans; Immunoblotting; Kidney; Lysosomes; Macrophages; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Open Reading Frames; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A; Phospholipases A2; Phospholipids; Plasmids; Pulmonary Surfactants; Rats; Sequence Homology, Amino Acid; Serine; Surface-Active Agents; Transfection | 2005 |
A phosphorylation-dependent export structure in ROMK (Kir 1.1) channel overrides an endoplasmic reticulum localization signal.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Arginine; Blotting, Western; Brefeldin A; Cell Membrane; Cytoplasm; Electrophysiology; Endoplasmic Reticulum; Glycosylation; Golgi Apparatus; Immunoprecipitation; Kidney Tubules, Collecting; Molecular Sequence Data; Mutation; Oocytes; Phosphorylation; Phosphoserine; Potassium; Potassium Channels, Inwardly Rectifying; Protein Structure, Tertiary; Rats; RNA, Complementary; Serine; Time Factors; Xenopus laevis | 2005 |
Alternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis.
Topics: Alanine; Bacteriophages; Base Sequence; Binding Sites; Carrier Proteins; Combinatorial Chemistry Techniques; Epitopes; Human Growth Hormone; Molecular Sequence Data; Mutagenesis; Peptide Library; Proteins; Sequence Homology, Amino Acid; Serine | 2005 |
Comparison of structure and dynamics of micelle-bound human alpha-synuclein and Parkinson disease variants.
Topics: Alanine; alpha-Synuclein; Amino Acid Sequence; Humans; Kinetics; Magnetic Resonance Spectroscopy; Micelles; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Mutation; Parkinson Disease; Point Mutation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Sodium Dodecyl Sulfate; Valine | 2005 |
BAD Ser128 is not phosphorylated by c-Jun NH2-terminal kinase for promoting apoptosis.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Apoptosis; bcl-Associated Death Protein; Erythropoietin; Fibroblasts; HeLa Cells; Humans; Interleukin-3; JNK Mitogen-Activated Protein Kinases; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Serine; Species Specificity; Threonine; Transfection | 2005 |
All four putative selectivity filter glycine residues in KtrB are essential for high affinity and selective K+ uptake by the KtrAB system from Vibrio alginolyticus.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Binding Sites; Biological Transport; Cation Transport Proteins; Cations; Cell Membrane; Escherichia coli; Genetic Variation; Glucosides; Glycine; Ions; Kinetics; Membrane Proteins; Models, Biological; Molecular Sequence Data; Plasmids; Potassium; Potassium Channels; Protein Binding; Protein Structure, Tertiary; Protein Transport; Serine; Sodium; Time Factors; Vibrio alginolyticus | 2005 |
Phosphorylation by protein kinase a inhibits nuclear import of 5-lipoxygenase.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alanine; Animals; Arachidonate 5-Lipoxygenase; Binding Sites; Biological Transport; Cell Nucleus; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Dinoprostone; Gene Expression; Glutamic Acid; Green Fluorescent Proteins; Kinetics; Mice; Mutagenesis, Site-Directed; NIH 3T3 Cells; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Recombinant Fusion Proteins; Serine; Structure-Activity Relationship; Transfection | 2005 |
Differential contribution of troponin I phosphorylation sites to the endothelin-modulated contractile response.
Topics: Actin Cytoskeleton; Adenoviridae; Alanine; Amiloride; Animals; Binding Sites; Calcium; Cells, Cultured; Cluster Analysis; Cyclic AMP-Dependent Protein Kinases; DNA, Complementary; Endothelins; Hydrogen-Ion Concentration; Models, Statistical; Muscle Cells; Mutagenesis; Myocardial Contraction; Myocardium; Phosphorylation; Protein Kinase C; Rats; Sarcomeres; Serine; Threonine; Time Factors; Troponin I | 2005 |
Retinoylserine and retinoylalanine, natural products of the moth Trichoplusia ni.
Topics: Alanine; Animals; Chromatography; Molecular Structure; Moths; Serine; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Tretinoin | 2005 |
Characterization of two new variants of human catechol O-methyltransferase in vitro.
Topics: Alanine; Breast Neoplasms; Catechol O-Methyltransferase; DNA Methylation; Equilenin; Escherichia coli; Estrogen Replacement Therapy; Female; Humans; Mutagenesis, Site-Directed; Plasmids; Polymorphism, Genetic; Serine; Temperature | 2005 |
New routes to beta-cycloalkylalanine derivatives using serine-derived organozinc reagents.
Topics: Alanine; Cycloparaffins; Molecular Structure; Organometallic Compounds; Serine; Zinc | 2005 |
Akt kinase phosphorylation of inositol 1,4,5-trisphosphate receptors.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Apoptosis; Calcium; Calcium Channels; Calcium-Transporting ATPases; Caspase 3; Caspases; Cell Line; Chlorocebus aethiops; CHO Cells; Chromones; COS Cells; Cricetinae; Detergents; DNA, Complementary; Enzyme Activation; Glutamic Acid; Humans; Immunoprecipitation; Inositol 1,4,5-Trisphosphate Receptors; Microcirculation; Molecular Sequence Data; Morpholines; Octoxynol; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Cytoplasmic and Nuclear; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine; Staurosporine; Time Factors; Transfection | 2006 |
Gln49 and Ser174 residues play critical roles in determining the catalytic efficiencies of plant glutamine synthetase.
Topics: Alanine; Amino Acid Sequence; Arabidopsis; Catalysis; Glutamate-Ammonia Ligase; Glutamine; Isoenzymes; Lysine; Molecular Sequence Data; Mutation; Quaternary Ammonium Compounds; Serine; Substrate Specificity | 2006 |
Posttranslational conversion of L-serines to D-alanines is vital for optimal production and activity of the lantibiotic lacticin 3147.
Topics: Alanine; Amino Acid Sequence; Bacteriocins; Chromatography, High Pressure Liquid; Codon; Glycine; Lactococcus lactis; Molecular Sequence Data; Protein Processing, Post-Translational; Serine; Structure-Activity Relationship; Threonine; Valine | 2005 |
Two brothers with mild congenital erythropoietic porphyria due to a novel genotype.
Topics: Adolescent; Alanine; Child, Preschool; Exons; Genetic Counseling; Genotype; Glycine; Humans; Male; Mutation; Mutation, Missense; Pedigree; Phenotype; Porphyria, Erythropoietic; Porphyrins; Promoter Regions, Genetic; Serine; Siblings; Uroporphyrinogen III Synthetase | 2005 |
Host-mediated phosphorylation of type III effector AvrPto promotes Pseudomonas virulence and avirulence in tomato.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Gene Expression; Glycine; Host-Parasite Interactions; Immunity, Innate; Models, Biological; Molecular Sequence Data; Nicotiana; Phosphorylation; Phosphotransferases; Plant Diseases; Plant Proteins; Protein Processing, Post-Translational; Pseudomonas syringae; Serine; Solanum lycopersicum; Spectrometry, Mass, Electrospray Ionization; Virulence | 2006 |
Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation.
Topics: Adenylyl Cyclases; Alanine; Arrestins; Aspartic Acid; beta-Arrestin 1; beta-Arrestin 2; beta-Arrestins; Binding Sites; Blotting, Western; Cell Line; Cell Membrane; Cyclic AMP-Dependent Protein Kinases; DNA, Complementary; Epinephrine; G-Protein-Coupled Receptor Kinase 1; Green Fluorescent Proteins; Humans; Isoproterenol; Kinetics; Mutation; Phosphorylation; Pindolol; Protein Structure, Tertiary; Protein Transport; Receptors, Adrenergic, beta-2; Serine; Time Factors; Transfection | 2006 |
Phosphorylation of serine 526 is required for MEKK3 activity, and association with 14-3-3 blocks dephosphorylation.
Topics: 14-3-3 Proteins; Alanine; Amino Acid Sequence; Catalysis; Cell Line; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Isoenzymes; MAP Kinase Kinase 6; MAP Kinase Kinase Kinase 3; Molecular Sequence Data; Mutagenesis, Site-Directed; NF-kappa B; Osmotic Pressure; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Serine; Signal Transduction; Threonine | 2006 |
Phospholemman inhibition of the cardiac Na+/Ca2+ exchanger. Role of phosphorylation.
Topics: Adenosine Triphosphatases; Alanine; Animals; Calsequestrin; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP-Dependent Protein Kinases; Glutamic Acid; Humans; Immunoblotting; Ions; Membrane Proteins; Mice; Mice, Knockout; Muscle Cells; Muscles; Mutation; Myocardium; Phosphoproteins; Phosphorylation; Serine; Sodium; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate; Transfection | 2006 |
Phosphorylation of the hinge domain of the nuclear hormone receptor LRH-1 stimulates transactivation.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Butadienes; Cell Line; Cell Nucleus; Cholesterol 7-alpha-Hydroxylase; DNA-Binding Proteins; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; HeLa Cells; Humans; Ligands; MAP Kinase Signaling System; Mitogens; Molecular Sequence Data; Mutation; Nitriles; Phosphoproteins; Phosphorylation; Plasmids; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Protein Transport; Rats; Receptors, Cytoplasmic and Nuclear; RNA Splicing Factors; Sequence Homology, Amino Acid; Serine; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection | 2006 |
Impact of the gliotoxin L-serine-O-sulphate on cellular metabolism in cultured rat astrocytes.
Topics: Alanine; Alanine Transaminase; Animals; Animals, Newborn; Aspartate Aminotransferases; Astrocytes; Carbon Radioisotopes; Cells, Cultured; Central Nervous System; Cerebral Cortex; Down-Regulation; Energy Metabolism; Glucose; Glutathione; Lathyrism; Neurotoxins; Nuclear Magnetic Resonance, Biomolecular; Rats; Rats, Wistar; Serine | 2006 |
Molecular and biochemical characterization of a serine racemase from Arabidopsis thaliana.
Topics: Alanine; Arabidopsis; Arginine; Catalysis; Cations, Divalent; Dimerization; Escherichia coli; Glutamine; Hydro-Lyases; Hydrogen-Ion Concentration; In Situ Hybridization, Fluorescence; Metals; Molecular Sequence Data; Pyridoxal Phosphate; Racemases and Epimerases; Sequence Homology, Amino Acid; Serine; Stereoisomerism; Substrate Specificity | 2006 |
Molecular characterization of serine-, alanine-, and proline-rich proteins of Trypanosoma cruzi and their possible role in host cell infection.
Topics: Alanine; Amino Acid Sequence; Animals; Calcium; Cell Adhesion Molecules; Genome, Protozoan; HeLa Cells; Humans; Molecular Sequence Data; Peptides; Proline; Proline-Rich Protein Domains; Protozoan Proteins; Serine; Trypanosoma cruzi | 2006 |
Functional role of catalytic triad and oxyanion hole-forming residues on enzyme activity of Escherichia coli thioesterase I/protease I/phospholipase L1.
Topics: Alanine; Asparagine; Catalytic Domain; Crystallography; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Glycine; Kinetics; Lysophospholipase; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Oligonucleotides; Periplasmic Proteins; Protein Conformation; Serine | 2006 |
Glycogen synthase kinase 3beta phosphorylates Alzheimer's disease-specific Ser396 of microtubule-associated protein tau by a sequential mechanism.
Topics: Alanine; Alzheimer Disease; Animals; Brain; Cattle; Cells, Cultured; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mutation; Phosphorylation; Serine; tau Proteins; Transfection; Tyrosine | 2006 |
Cocaine self-administration in mice is inversely related to phosphorylation at Thr34 (protein kinase A site) and Ser130 (kinase CK1 site) of DARPP-32.
Topics: Alanine; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Corpus Striatum; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microdialysis; Phosphorylation; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Serine; Threonine; Time Factors | 2006 |
Time dependent density functional theory modeling of chiroptical properties of small amino acids in solution.
Topics: Alanine; Computer Simulation; Glycine; Models, Chemical; Proline; Quantum Theory; Serine; Solutions; Time Factors | 2006 |
A region in urokinase plasminogen receptor domain III controlling a functional association with alpha5beta1 integrin and tumor growth.
Topics: Alanine; Biotinylation; Cell Line, Tumor; Crystallography, X-Ray; Humans; Integrin alpha5beta1; Models, Molecular; Neoplasms; Peptides; Protein Structure, Tertiary; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Serine; Signal Transduction | 2006 |
Cytoplasmic domain phosphorylation of heparin-binding EGF-like growth factor.
Topics: Alanine; Amino Acid Sequence; Animals; Anisomycin; Cell Line; Chlorocebus aethiops; Cytoplasm; Epidermal Growth Factor; Gene Expression Regulation; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Ionophores; Lysophospholipids; Male; Mice; Mice, Nude; Molecular Sequence Data; Mutation; Neoplasms, Experimental; Peptide Fragments; Phosphorylation; Protein Structure, Tertiary; Serine; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Vero Cells | 2006 |
Long stretches of sequential and identical serine or alanine codons are compatible with an efficient full-length protein expression in Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Codon; Escherichia coli; Genetic Vectors; Glutathione Transferase; Models, Genetic; Molecular Sequence Data; Recombinant Fusion Proteins; Schistosoma japonicum; Serine | 2006 |
Podospora anserina target of rapamycin.
Topics: Alanine; Alleles; Amino Acid Motifs; Amino Acid Sequence; Antifungal Agents; Base Sequence; Consensus Sequence; Fungal Proteins; Genes, Fungal; Growth; Hyphae; Molecular Sequence Data; Molecular Weight; Mutation, Missense; Open Reading Frames; Podospora; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Sirolimus; Vacuoles | 2006 |
NMR and alanine scan studies of glucose-dependent insulinotropic polypeptide in water.
Topics: Alanine; Amino Acid Sequence; Animals; Gastric Inhibitory Polypeptide; Glucose; Glutamine; Insulin; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Protein Conformation; Protein Structure, Secondary; Rats; Serine | 2006 |
Syndapin I is the phosphorylation-regulated dynamin I partner in synaptic vesicle endocytosis.
Topics: Acyltransferases; Alanine; Animals; Animals, Newborn; Binding Sites; Calcineurin; Carrier Proteins; Cells, Cultured; Cytoskeletal Proteins; Dynamin I; Endocytosis; Glutamic Acid; Macromolecular Substances; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Peptides; Phosphorylation; Presynaptic Terminals; Protein Binding; Rats; Rats, Sprague-Dawley; Serine; Synaptic Transmission; Synaptic Vesicles; Synaptosomes | 2006 |
Characterization of a membrane protein folding motif, the Ser zipper, using designed peptides.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Dimerization; Disulfides; Electron Transport Complex IV; Lipid Bilayers; Membrane Proteins; Micelles; Models, Molecular; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phospholipids; Protein Folding; Receptors, Erythropoietin; Serine; Sulfhydryl Compounds; Thermodynamics; Ultracentrifugation | 2006 |
Correlation between plasma levels of glutamate, alanine and serine with severity of depression.
Topics: Adult; Alanine; Amino Acids; Chromatography, High Pressure Liquid; Depressive Disorder; Female; Glutamic Acid; Humans; Male; Psychiatric Status Rating Scales; Serine; Spectrometry, Fluorescence | 2006 |
Phosphorylation of the norepinephrine transporter at threonine 258 and serine 259 is linked to protein kinase C-mediated transporter internalization.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Cells, Cultured; Down-Regulation; Enzyme Activation; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Phosphorylation; Protein Kinase C; Rats; Serine; Threonine | 2006 |
Phosphorylation and 14-3-3 binding of Arabidopsis trehalose-phosphate synthase 5 in response to 2-deoxyglucose.
Topics: 14-3-3 Proteins; Alanine; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Arabidopsis; Arabidopsis Proteins; Binding Sites; Cells, Cultured; Chromatography, Affinity; Deoxyglucose; Glucosyltransferases; Humans; Immunoprecipitation; Multienzyme Complexes; Mutation, Missense; Phenformin; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Serine; Threonine | 2006 |
Identification of mammalian mitochondrial proteins that interact with IAPs via N-terminal IAP binding motifs.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Apoptosis Regulatory Proteins; Carrier Proteins; Caspase Inhibitors; Enzyme Inhibitors; Glutamate Dehydrogenase; High-Temperature Requirement A Serine Peptidase 2; Humans; Inhibitor of Apoptosis Proteins; Leucine-Rich Repeat Proteins; Mammals; Mice; Mitochondrial Proteins; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Proteins; Proteomics; Serine; Serine Endopeptidases; X-Linked Inhibitor of Apoptosis Protein | 2007 |
Investigation of resistance mechanisms to fipronil in diamondback moth (Lepidoptera: Plutellidae).
Topics: Alanine; Alleles; Amino Acid Substitution; Animals; Base Sequence; Dieldrin; Endosulfan; Insecticide Resistance; Insecticides; Molecular Sequence Data; Moths; Mutation, Missense; Pyrazoles; Sequence Analysis, DNA; Serine | 2006 |
Considerations on the lactate consumption by CHO cells in the presence of galactose.
Topics: Alanine; Animals; Asparagine; Bioreactors; Carbohydrate Metabolism; Cell Culture Techniques; Cell Survival; CHO Cells; Cricetinae; Culture Media; Galactose; Gluconeogenesis; Glucose; Glutamic Acid; Lactic Acid; Models, Biological; Serine | 2006 |
Lipid solvation effects contribute to the affinity of Gly-xxx-Gly motif-mediated helix-helix interactions.
Topics: Alanine; Amino Acid Motifs; Amino Acid Substitution; Bacteriophage M13; Cell Membrane; Dimerization; Glycine; Glycophorins; Lipids; Molecular Sequence Data; Mutation; Protein Conformation; Protein Folding; Protein Structure, Secondary; Serine; Solubility; Viral Core Proteins | 2006 |
Calmodulin isoform-specific activation of a rice calmodulin-binding kinase conferred by only three amino-acids of OsCaM61.
Topics: Alanine; Amino Acid Sequence; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Electrophoretic Mobility Shift Assay; Enzyme Activation; Glycine; Molecular Sequence Data; Mutation; Oryza; Protein Isoforms; Sequence Alignment; Serine; Spectrometry, Fluorescence | 2006 |
The interaction of Fusarium solani pisi cutinase with long chain spin label esters.
Topics: Alanine; Carboxylic Ester Hydrolases; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Esters; Free Radicals; Fungal Proteins; Fusarium; Micelles; Nuclear Magnetic Resonance, Biomolecular; Protein Folding; Protein Structure, Secondary; Serine; Spin Labels; Substrate Specificity | 2006 |
Ab-initio and density functional study of L- and D-forms of alanine and serine in gas phase and bulk aqueous medium.
Topics: Alanine; Gases; Models, Chemical; Serine; Solutions; Static Electricity; Stereoisomerism; Thermodynamics | 2007 |
Prospective study of FGFR3 mutations as a prognostic factor in nonmuscle invasive urothelial bladder carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Cysteine; Female; Glutamic Acid; Glycine; Humans; Leucine; Male; Middle Aged; Multivariate Analysis; Mutation; Phenylalanine; Polymerase Chain Reaction; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Receptor, Fibroblast Growth Factor, Type 3; Sequence Analysis, DNA; Serine; Tyrosine; Urinary Bladder Neoplasms | 2006 |
Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration.
Topics: Acetylation; Alanine; Alanine-tRNA Ligase; Animals; Catalysis; Escherichia coli; Fibroblasts; Humans; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Models, Molecular; Molecular Sequence Data; Mutation; Neurodegenerative Diseases; Phenotype; Protein Folding; Protein Structure, Tertiary; Purkinje Cells; RNA, Transfer, Ala; Serine | 2006 |
Molecular biology: sticky end in protein synthesis.
Topics: Alanine; Alanine-tRNA Ligase; Animals; Genetic Code; Humans; Mice; Mutation; Neurodegenerative Diseases; Protein Biosynthesis; Purkinje Cells; RNA, Transfer, Ala; Serine | 2006 |
Graded regulation of the Kv2.1 potassium channel by variable phosphorylation.
Topics: Alanine; Alkaline Phosphatase; Animals; Aspartic Acid; Brain; Calcineurin; Calcium; Cell Line; Chromatography, Liquid; Humans; Ion Channel Gating; Ionomycin; Mass Spectrometry; Mutation; Neurons; Patch-Clamp Techniques; Phosphorylation; Phosphoserine; Phosphothreonine; Point Mutation; Rats; Recombinant Proteins; Serine; Shab Potassium Channels; Transfection | 2006 |
Gain of function mutants reveal sites important for the interaction of the atypical inhibitors benztropine and bupropion with monoamine transporters.
Topics: Alanine; Animals; Benztropine; Binding, Competitive; Biological Transport; Bupropion; Chlorocebus aethiops; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Models, Molecular; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Radioligand Assay; Serine; Transfection; Tritium | 2006 |
Archaeal N-terminal protein maturation commonly involves N-terminal acetylation: a large-scale proteomics survey.
Topics: Acetylation; Alanine; Amino Acid Sequence; Aminopeptidases; Archaeal Proteins; Conserved Sequence; Halobacterium salinarum; Mass Spectrometry; Methionyl Aminopeptidases; Models, Biological; Peptide Fragments; Protein Biosynthesis; Protein Processing, Post-Translational; Proteomics; Serine; Substrate Specificity | 2006 |
DsdX is the second D-serine transporter in uropathogenic Escherichia coli clinical isolate CFT073.
Topics: Alanine; Amino Acid Transport Systems; Biological Transport; Culture Media; Cycloserine; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Glycine; Kinetics; Membrane Transport Proteins; Models, Biological; Serine; Threonine | 2006 |
Increase of RNase a N-terminus polarity or C-terminus apolarity changes the two domains' propensity to swap and form the two dimeric conformers of the protein.
Topics: Alanine; Amino Acid Substitution; Animals; Cattle; Circular Dichroism; Dimerization; Enzyme Stability; Guanidine; Mutagenesis, Site-Directed; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Ribonuclease, Pancreatic; Serine | 2006 |
The uptake of amino acids by the cyanobacterium Planktothrix rubescens is stimulated by light at low irradiances.
Topics: Acetates; Alanine; Amino Acids; Carbon Isotopes; Cyanobacteria; Dose-Response Relationship, Radiation; Glutamic Acid; Glycine; Leucine; Light; Nitrogen; Serine | 2006 |
Quantification of serine enantiomers in rat brain microdialysate using Marfey's reagent and LC/MS/MS.
Topics: Alanine; Animals; Brain; Chromatography, High Pressure Liquid; Dinitrobenzenes; Microdialysis; Rats; Reproducibility of Results; Sensitivity and Specificity; Serine; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism | 2007 |
The role of a conserved serine residue within hydrogen bonding distance of FAD in redox properties and the modulation of catalysis by Ca2+/calmodulin of constitutive nitric-oxide synthases.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Calcium; Calmodulin; Catalysis; Electron Transport; Flavin-Adenine Dinucleotide; Humans; Hydrogen Bonding; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Oxidation-Reduction; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Serine; Threonine | 2006 |
Proximal influences in two-on-two globins: effect of the Ala69Ser replacement on Synechocystis sp. PCC 6803 hemoglobin.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cyanides; Ferric Compounds; Globins; Heme; Histidine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Myoglobin; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Denaturation; Recombinant Proteins; Serine; Sperm Whale; Structure-Activity Relationship; Synechocystis; Temperature; Urea | 2006 |
BRF1 protein turnover and mRNA decay activity are regulated by protein kinase B at the same phosphorylation sites.
Topics: Alanine; Amino Acid Substitution; Animals; Butyrate Response Factor 1; Cell Line, Tumor; Humans; Mice; Mice, Knockout; Mutagenesis, Site-Directed; NIH 3T3 Cells; Nuclear Proteins; Phosphorylation; Proto-Oncogene Proteins c-akt; RNA Stability; RNA-Binding Proteins; RNA, Messenger; Serine; Signal Transduction; Transcription Factor TFIIIB | 2006 |
(2R)- and (2S)-3-fluoroalanine and their N-methyl derivatives: synthesis and incorporation in peptide scaffolds.
Topics: Alanine; Amides; Amino Acids; Indicators and Reagents; Mass Spectrometry; Methylation; Oxazolidinones; Peptides; Serine | 2006 |
Ser46 phosphorylation regulates p53-dependent apoptosis and replicative senescence.
Topics: Alanine; Animals; Apoptosis; Cell Proliferation; Cellular Senescence; DNA Damage; DNA-Binding Proteins; Embryo, Mammalian; Exons; Fibroblasts; Humans; Mice; Mice, Mutant Strains; Mutation; Phosphorylation; Phosphoserine; Radiation, Ionizing; Serine; Thymus Gland; Tumor Suppressor Protein p53 | 2006 |
Is glycine a surrogate for a D-amino acid in the collagen triple helix?
Topics: Alanine; Amino Acids; Circular Dichroism; Collagen; Glycine; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Peptides; Protein Conformation; Protein Folding; Serine; Thermodynamics | 2007 |
Acidic pH-induced conformational changes in amyloidogenic mutant transthyretin.
Topics: Alanine; Amyloid; Crystallography, X-Ray; Humans; Hydrogen-Ion Concentration; Models, Molecular; Mutant Proteins; Prealbumin; Protein Structure, Secondary; Serine; Time Factors | 2007 |
Phosphoacceptor site S173 in the regulatory domain of Epstein-Barr Virus ZEBRA protein is required for lytic DNA replication but not for activation of viral early genes.
Topics: Alanine; Deoxyribonuclease I; DNA Replication; DNA-Binding Proteins; Gene Expression Regulation, Viral; Herpesvirus 4, Human; Molecular Mimicry; Mutation; Phenotype; Phosphorylation; Regulatory Elements, Transcriptional; Serine; Solubility; Time Factors; Trans-Activators; Viral Proteins | 2007 |
Antithrombin Cambridge II (A384S): an underestimated genetic risk factor for venous thrombosis.
Topics: Adult; Alanine; Antithrombin III; Case-Control Studies; Cohort Studies; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Models, Molecular; Mutation, Missense; Pedigree; Risk Factors; Serine; Venous Thrombosis | 2007 |
Quantitative evaluation of human delta opioid receptor desensitization using the operational model of drug action.
Topics: Alanine; Animals; Arrestins; beta-Arrestins; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Endocytosis; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Models, Biological; Mutation; Oligopeptides; Phosphorylation; Receptors, Opioid, delta; Serine; Time Factors | 2007 |
Enhanced NFATc1 nuclear occupancy causes T cell activation independent of CD28 costimulation.
Topics: Active Transport, Cell Nucleus; Alanine; Amino Acid Substitution; Animals; CD28 Antigens; Cell Nucleus; Cell Proliferation; Cyclosporine; Cytokines; Female; Glycogen Synthase Kinase 3; Lymphocyte Activation; Male; Mice; NFATC Transcription Factors; Phosphorylation; Receptors, Antigen, T-Cell; Serine; T-Lymphocytes; Th1 Cells; Th2 Cells | 2007 |
Alanine to serine polymorphism at position 986 of the calcium-sensing receptor associated with coronary heart disease, myocardial infarction, all-cause, and cardiovascular mortality.
Topics: Adult; Aged; Alanine; Calcium; Cause of Death; Coronary Angiography; Coronary Disease; Female; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Myocardial Infarction; Parathyroid Hormone; Phosphates; Polymorphism, Genetic; Receptors, Calcium-Sensing; Risk Factors; Serine | 2007 |
Major Cdk5-dependent phosphorylation sites of amphiphysin 1 are implicated in the regulation of the membrane binding and endocytosis.
Topics: Alanine; Animals; Cyclin-Dependent Kinase 5; Drug Interactions; Endocytosis; Humans; Lipids; Liposomes; Mass Spectrometry; Microscopy, Electron, Scanning; Mutagenesis; Nerve Tissue Proteins; PC12 Cells; Phosphorylation; Protein Kinase Inhibitors; Purines; Rats; Roscovitine; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Transfection | 2007 |
Effect of selected Ser/Ala and Xaa/Pro mutations on the stability and catalytic properties of a cold adapted subtilisin-like serine proteinase.
Topics: Alanine; Amino Acids; Catalysis; Cold Temperature; Enzyme Stability; Kinetics; Models, Molecular; Mutation; Proline; Protein Structure, Tertiary; Serine; Subtilisin; Temperature; Vibrio | 2007 |
An N-terminal nucleotide-binding site in VDAC1: involvement in regulating mitochondrial function.
Topics: Adenosine Triphosphate; Alanine; Apoptosis; Binding Sites; Cell Line; Cell Proliferation; Cytosol; Glycine; Humans; Lysine; Mitochondria; Mitochondrial Membranes; Mutation; Permeability; Protein Structure, Tertiary; RNA Interference; RNA, Small Interfering; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Time Factors; Transfection; Voltage-Dependent Anion Channel 1 | 2007 |
Aspartate-444 is essential for productive substrate interactions in a neuronal glutamate transporter.
Topics: Alanine; Animals; Aspartic Acid; Binding Sites; Cysteine; Dicarboxylic Acid Transporters; Excitatory Amino Acid Transporter 3; Glutamic Acid; HeLa Cells; Humans; Microinjections; Mutation; Neurons; Oocytes; Protein Conformation; Protein Structure, Tertiary; Rabbits; Serine; Succinic Acid; Transfection; Xenopus laevis | 2007 |
The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo.
Topics: Alanine; Animals; Aspartic Acid; Brain Ischemia; Cerebral Arteries; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Male; Mice; Mice, Transgenic; Mutation; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphorylation; Regional Blood Flow; Serine; Stroke | 2007 |
Nonconserved residues Ala287 and Ser290 of the Cryptosporidium hominis thymidylate synthase domain facilitate its rapid rate of catalysis.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Cryptosporidium; Crystallography, X-Ray; Folic Acid; Kinetics; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Protozoan Proteins; Quinazolines; Serine; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymidine Monophosphate; Thymidylate Synthase | 2007 |
Alanine scanning of the hepatitis C virus core protein reveals numerous residues essential for production of infectious virus.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cell Line; Genome, Viral; Hepacivirus; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Serine; Viral Core Proteins; Virion; Virus Replication | 2007 |
GDI-1 phosphorylation switch at serine 96 induces RhoA activation and increased endothelial permeability.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cell Membrane Permeability; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Genes, Reporter; Green Fluorescent Proteins; Guanine Nucleotide Dissociation Inhibitors; Humans; Luciferases; Mutation; Phosphorylation; Protein Kinase C-alpha; Pulmonary Artery; rhoA GTP-Binding Protein; Serine; Thrombin; Transfection | 2007 |
The Rad9-Hus1-Rad1 checkpoint clamp regulates interaction of TopBP1 with ATR.
Topics: Alanine; Amino Acid Sequence; Animals; Ataxia Telangiectasia Mutated Proteins; Carrier Proteins; Cell Cycle Proteins; Chromosomal Proteins, Non-Histone; DNA-Binding Proteins; Gene Expression Regulation; Molecular Sequence Data; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Xenopus laevis; Xenopus Proteins | 2007 |
WNK4 phosphorylates ser(206) of claudin-7 and promotes paracellular Cl(-) permeability.
Topics: Alanine; Amino Acid Substitution; Animals; Cell Membrane Permeability; Chlorides; Epithelium; Kidney; Kidney Tubules; LLC-PK1 Cells; Membrane Proteins; Mutagenesis, Site-Directed; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Rats; Serine; Swine; Tight Junctions | 2007 |
The LOC387715 polymorphism, inflammatory markers, smoking, and age-related macular degeneration. A population-based case-control study.
Topics: Aged; Aged, 80 and over; Alanine; Biomarkers; C-Reactive Protein; Case-Control Studies; Genetic Predisposition to Disease; Genotype; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-6; Macular Degeneration; Plasminogen Activator Inhibitor 1; Polymorphism, Genetic; Proteins; Risk Assessment; Serine; Smoking | 2008 |
Combinations of two amino acids (Ala40 and Phe75 or Ser40 and Tyr75) in the coat protein of apple chlorotic leaf spot virus are crucial for infectivity.
Topics: Alanine; Amino Acid Sequence; DNA Primers; Flexiviridae; Malus; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Plant Diseases; Plant Leaves; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Deletion; Sequence Homology, Amino Acid; Serine; Tyrosine; Virus Replication | 2007 |
Stereoselective syntheses of 4-oxa diaminopimelic acid and its protected derivatives via aziridine ring opening.
Topics: Alanine; Amino Acids; Aziridines; Catalysis; Diaminopimelic Acid; Haemophilus influenzae; Molecular Structure; Racemases and Epimerases; Serine; Stereoisomerism; Sulfides; Threonine | 2007 |
Metabolic impact of overexpression of liver glycogen synthase with serine-to-alanine substitutions in rat primary hepatocytes.
Topics: Alanine; Amino Acid Substitution; Animals; Cells, Cultured; Glucose; Glucose-6-Phosphate; Glycogen; Glycogen Synthase; Hepatocytes; Male; Rats; Rats, Wistar; Serine | 2007 |
Antithrombin Cambridge II (A384S): prevalence in patients of the Paris Thrombosis Study (PATHROS).
Topics: Alanine; Antithrombin III; Case-Control Studies; Humans; Mutation; Paris; Serine; Thrombosis | 2007 |
The N-terminal region of ABC50 interacts with eukaryotic initiation factor eIF2 and is a target for regulatory phosphorylation by CK2.
Topics: Alanine; ATP-Binding Cassette Transporters; Binding Sites; Casein Kinase II; Cell Line; Escherichia coli; Eukaryotic Initiation Factor-2; Humans; Phosphoamino Acids; Phosphorylation; Plasmids; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Serine | 2008 |
Alteration of the quaternary structure of human UDP-glucose dehydrogenase by a double mutation.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Chromatography, Gel; Chromatography, High Pressure Liquid; Humans; Kinetics; Mutation; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Serine; Structure-Activity Relationship; Uridine Diphosphate Glucose Dehydrogenase | 2007 |
Fibrinogen Leipzig II (gamma351Gly-->Ser and gamma82Ala-->Gly): hypodysfibrinogenaemia due to two independent amino acid substitutions within the same polypeptide chain.
Topics: Adult; Afibrinogenemia; Alanine; Fibrinogen; Glycine; Haplotypes; Hemorrhage; Heterozygote; Humans; Male; Models, Genetic; Mutation; Serine; Spectrometry, Mass, Electrospray Ionization; Time Factors | 2007 |
Rod1, an arrestin-related protein, is phosphorylated by Snf1-kinase in Saccharomyces cerevisiae.
Topics: Alanine; Amino Acid Substitution; AMP-Activated Protein Kinases; Arrestin; Carrier Proteins; Dinitrobenzenes; Drug Resistance, Fungal; Fungal Proteins; Gene Expression Regulation, Fungal; Membrane Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Transcription Factors | 2007 |
Identification of four major hornet silk genes with a complex of alanine-rich and serine-rich sequences in Vespa simillima xanthoptera Cameron.
Topics: Alanine; Amino Acid Sequence; Animals; DNA, Complementary; Genes, Insect; Insect Proteins; Molecular Sequence Data; Protein Structure, Secondary; Sequence Analysis, Protein; Serine; Silk; Wasps | 2007 |
The M129V polymorphism of codon 129 in the prion gene (PRNP) in the Danish population.
Topics: Adult; Aged; Alanine; Alleles; Codon; Creutzfeldt-Jakob Syndrome; Denmark; Female; Genotype; Humans; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Prion Proteins; Prions; Serine; Valine | 2008 |
Transthyretin Ala97Ser in Chinese-Taiwanese patients with familial amyloid polyneuropathy: genetic studies and phenotype expression.
Topics: Aged; Alanine; Amino Acid Substitution; Amyloid Neuropathies, Familial; Asian People; Axons; DNA Mutational Analysis; Female; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Male; Middle Aged; Mutation, Missense; Peripheral Nerves; Phenotype; Prealbumin; Serine; Taiwan; Wallerian Degeneration | 2008 |
The Escherichia coli TatABC system and a Bacillus subtilis TatAC-type system recognise three distinct targeting determinants in twin-arginine signal peptides.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Arginine; Bacillus subtilis; Bacterial Proteins; Consensus Sequence; Escherichia coli; Genes, Bacterial; Green Fluorescent Proteins; Lysine; Membrane Transport Proteins; Molecular Sequence Data; Phenylalanine; Protein Sorting Signals; Protein Structure, Tertiary; Protein Transport; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Species Specificity; Substrate Specificity | 2008 |
Serine-7 of the RNA polymerase II CTD is specifically required for snRNA gene expression.
Topics: Alanine; Amino Acid Sequence; Cell Line; Consensus Sequence; Gene Expression Regulation; Heterogeneous-Nuclear Ribonucleoproteins; Humans; Mutation; Oligopeptides; Phosphorylation; Protein Structure, Tertiary; Protein Subunits; RNA Polymerase II; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Small Nuclear; Serine; Templates, Genetic; Transcription, Genetic | 2007 |
Processing of N-terminal unnatural amino acids in recombinant human interferon-beta in Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Base Sequence; Binding Sites; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Glycine; Histidine; Humans; Interferon Type I; Molecular Sequence Data; Protein Engineering; Recombinant Proteins; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2008 |
A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of eukaryotic initiation factor 2B.
Topics: Alanine; Amino Acid Substitution; Amino Acids; Animals; Carcinoma, Hepatocellular; Catalytic Domain; Cell Line; Cell Line, Tumor; Cells, Cultured; Cycloheximide; Embryo, Mammalian; Eukaryotic Initiation Factor-2B; Fibroblasts; Genes, Reporter; Histidine; Humans; Jurkat Cells; Kidney; Liver Neoplasms; Luciferases, Renilla; Mice; Models, Biological; Peptide Mapping; Phosphorylation; Protein Biosynthesis; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Serine; Time Factors; Transfection | 2008 |
New functional single nucleotide polymorphism (Ala72Ser) in the COMT gene is associated with aggressive behavior in male schizophrenia.
Topics: Aggression; Alanine; Amino Acid Substitution; Catechol O-Methyltransferase; Genotype; Haplotypes; Homicide; Humans; Male; Polymorphism, Single Nucleotide; Schizophrenia; Serine | 2008 |
Functional and structural roles of conserved cysteine residues in the carboxyl-terminal domain of the follicle-stimulating hormone receptor in human embryonic kidney 293 cells.
Topics: Alanine; Amino Acid Sequence; Cell Line; Computer Simulation; Cyclic AMP; Cysteine; Humans; Kidney; Lipoylation; Molecular Sequence Data; Mutation; Receptors, FSH; Serine; Threonine | 2008 |
An unstable targeted allele of the mouse Mitf gene with a high somatic and germline reversion rate.
Topics: Alanine; Alleles; Amino Acid Substitution; Animals; Drug Resistance; Female; Fluorescent Antibody Technique; Gene Expression Regulation; Gene Targeting; Germ-Line Mutation; Homozygote; In Situ Hybridization, Fluorescence; Introns; Male; Mice; Microphthalmia-Associated Transcription Factor; Mutagenesis, Insertional; Neomycin; Phenotype; Pigmentation; RNA, Messenger; Sequence Analysis, DNA; Serine | 2008 |
Properties of serine:glyoxylate aminotransferase purified from Arabidopsis thaliana leaves.
Topics: Alanine; Arabidopsis; Dimerization; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Weight; Plant Leaves; Protein Structure, Secondary; Recombinant Proteins; Serine; Substrate Specificity; Tandem Mass Spectrometry; Transaminases | 2008 |
Replacement of two invariant serine residues in chorismate synthase provides evidence that a proton relay system is essential for intermediate formation and catalytic activity.
Topics: Alanine; Amino Acid Substitution; Catalysis; Flavin Mononucleotide; Flavins; Histidine; Hydrogen Bonding; Mutagenesis, Site-Directed; Neurospora crassa; Phosphorus-Oxygen Lyases; Protein Binding; Protons; Serine; Shikimic Acid; Substrate Specificity | 2008 |
Investigation of the mechanisms of tissue factor-mediated evasion of tumour cells from cellular cytotoxicity.
Topics: Alanine; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Immune System; Models, Biological; Mutagenesis, Site-Directed; Neoplasm Metastasis; Peptides; Phosphorylation; Protein Structure, Tertiary; Serine; Thromboplastin; Transfection; Vascular Cell Adhesion Molecule-1 | 2008 |
Effect of N-chloroamino acids on the erythrocyte.
Topics: Alanine; Amino Acids; Aspartic Acid; Chloramines; Dose-Response Relationship, Drug; Drug Stability; Erythrocytes; Fluoresceins; Glutathione; Glutathione Disulfide; Hemolysis; Humans; Hypochlorous Acid; Lysine; Osmotic Fragility; Oxidants; Oxidation-Reduction; Oxidative Stress; Phenylalanine; Serine | 2008 |
Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation.
Topics: 3T3-L1 Cells; Adaptor Proteins, Signal Transducing; Alanine; Amino Acid Substitution; Animals; Humans; Insulin; Mechanistic Target of Rapamycin Complex 1; Mice; Multiprotein Complexes; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinases; Proteins; Regulatory-Associated Protein of mTOR; Serine; TOR Serine-Threonine Kinases; Transcription Factors | 2008 |
Natural occurrence of microcystin synthetase deletion mutants capable of producing microcystins in strains of the genus Anabaena (Cyanobacteria).
Topics: Alanine; Anabaena; Bacterial Proteins; DNA, Bacterial; Microcystins; Molecular Sequence Data; Molecular Structure; Peptide Synthases; Phylogeny; Polymerase Chain Reaction; Protein Structure, Tertiary; Sequence Analysis, DNA; Sequence Deletion; Sequence Homology; Serine; Water Microbiology | 2008 |
TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Amyotrophic Lateral Sclerosis; Brain; Child; Dementia; DNA Mutational Analysis; DNA-Binding Proteins; Family Health; Female; Glycine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Serine; Ubiquitin | 2008 |
Role of disulfide bonds in goose-type lysozyme.
Topics: Alanine; Animals; Biochemistry; Catalysis; Cysteine; Disulfides; Geese; Hydrogen-Ion Concentration; Models, Molecular; Muramidase; Mutation; Protein Conformation; Serine; Struthioniformes; Temperature | 2008 |
Circadian changes of D-alanine and related compounds in rats and the effect of restricted feeding on their amounts.
Topics: Alanine; Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Circadian Rhythm; Corticosterone; Feeding Behavior; Insulin; Male; Melatonin; Pancreas; Pituitary Gland, Anterior; Rats; Rats, Wistar; Serine; Stereoisomerism | 2008 |
Interaction of hepatitis C virus nonstructural protein 5A with core protein is critical for the production of infectious virus particles.
Topics: Alanine; Amino Acid Sequence; Capsid Proteins; Fluorescent Antibody Technique, Indirect; Humans; Molecular Sequence Data; Mutation; Phosphorylation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Subcellular Fractions; Viral Nonstructural Proteins; Virion; Virus Replication | 2008 |
Stereoselective synthesis of triply isotope-labeled Ser, Cys, and Ala: amino acids for stereoarray isotope labeling technology.
Topics: Alanine; Amino Acids; Cysteine; Isotope Labeling; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Biology; Serine; Stereoisomerism | 2008 |
N-chloroamino acids cause oxidative protein modifications in the erythrocyte membrane.
Topics: Acetylcholinesterase; Alanine; Aspartic Acid; beta-Alanine; Chloramines; Disulfides; Erythrocyte Membrane; Humans; Kinetics; Lysine; Oxygen; Proteins; Serine; Sulfhydryl Compounds; Tyrosine | 2008 |
A double role for a strictly conserved serine: further insights into the dUTPase catalytic mechanism.
Topics: Alanine; Catalysis; Dimerization; Enzyme Stability; Escherichia coli; Guanidine; Hydrogen Bonding; Hydrolysis; Kinetics; Magnesium; Mutation; Protein Binding; Protein Structure, Secondary; Pyrophosphatases; Serine; Substrate Specificity; Thermodynamics | 2008 |
Muscle-specific IRS-1 Ser->Ala transgenic mice are protected from fat-induced insulin resistance in skeletal muscle.
Topics: Alanine; Amino Acid Substitution; Animals; Blotting, Western; Dietary Fats; Female; Glucose Clamp Technique; Glucose Tolerance Test; Immunoprecipitation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Skeletal; Phosphorylation; Serine; Triglycerides | 2008 |
Protein kinase a mediates activity-dependent Kv4.2 channel trafficking.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Green Fluorescent Proteins; Hippocampus; Isoquinolines; Mutation; Neurons; Phosphorylation; Protein Transport; Rats; Rats, Sprague-Dawley; Serine; Shal Potassium Channels; Sulfonamides; Transfection | 2008 |
Development of a temperature gradient focusing method for in situ extraterrestrial biomarker analysis.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Aspartic Acid; Biomarkers; Countercurrent Distribution; Electrophoresis, Microchip; Extraterrestrial Environment; Glutamic Acid; Glycine; Life; Mars; Serine; Soil; Space Flight; Stereoisomerism; Temperature; Valine | 2008 |
Spectroscopic labeling of A, S/T in the 1H-15N HSQC spectrum of uniformly (15N-13C) labeled proteins.
Topics: Alanine; Amino Alcohols; Butylene Glycols; Carbon Isotopes; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Proteins; Protons; Serine; Spin Labels; Staining and Labeling | 2008 |
Natural homolog of tRNA synthetase editing domain rescues conditional lethality caused by mistranslation.
Topics: Alanine; Amino Acid Sequence; Amino Acyl-tRNA Synthetases; Aminoacylation; Catalysis; Genetic Complementation Test; Lysine; Models, Biological; Molecular Sequence Data; Protein Biosynthesis; Protein Structure, Tertiary; RNA, Transfer; Sequence Homology, Amino Acid; Serine; Transgenes | 2008 |
Inflammatory cytokines induce phosphorylation and ubiquitination of prostate suppressor protein NKX3.1.
Topics: Alanine; Cell Line, Tumor; Cytokines; Homeodomain Proteins; Humans; Inflammation Mediators; Male; Mutagenesis, Site-Directed; Phosphorylation; Prostate; Serine; Transcription Factors; Ubiquitin | 2008 |
Misacylation of pyrrolysine tRNA in vitro and in vivo.
Topics: Alanine; Alanine-tRNA Ligase; Archaeal Proteins; Escherichia coli; Lysine; Methanosarcina barkeri; Methyltransferases; Mutation; RNA, Archaeal; RNA, Transfer, Lys; Serine; Serine-tRNA Ligase; Transfer RNA Aminoacylation | 2008 |
On the pH regulation of plant aquaporins.
Topics: Alanine; Aquaporins; Cell Membrane; Cytosol; Gene Expression Regulation, Plant; Histidine; Hydrogen-Ion Concentration; Mutation; Nicotiana; Permeability; Phosphorylation; Plant Proteins; Protoplasts; Serine; Time Factors | 2008 |
Polo-like kinase 1 phosphorylates and regulates Bcl-x(L) during pironetin-induced apoptosis.
Topics: Alanine; Apoptosis; bcl-X Protein; Cell Cycle Proteins; Cell Line, Tumor; Humans; Mutation; Phosphorylation; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pyrones; Serine | 2009 |
Unchanged beta-adrenergic stimulation of cardiac L-type calcium channels in Ca v 1.2 phosphorylation site S1928A mutant mice.
Topics: Alanine; Animals; Calcium Channels, L-Type; Cyclic AMP-Dependent Protein Kinases; Echocardiography; Electrophysiology; Mice; Mice, Transgenic; Models, Biological; Mutation; Myocytes, Cardiac; Phosphorylation; Receptors, Adrenergic, beta; Serine | 2008 |
Kinetic characterization of lipid II-Ala:alanyl-tRNA ligase (MurN) from Streptococcus pneumoniae using semisynthetic aminoacyl-lipid II substrates.
Topics: Alanine; Bacterial Proteins; Biochemistry; Catalysis; Cross-Linking Reagents; Drug Resistance, Microbial; Kinetics; Lipids; Mass Spectrometry; Models, Chemical; Penicillins; Peptide Synthases; Recombinant Proteins; Serine; Streptococcus pneumoniae | 2008 |
Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.
Topics: 4-Aminopyridine; Action Potentials; Alanine; Anesthetics, Inhalation; Animals; Biophysics; Dose-Response Relationship, Drug; GABA Agonists; gamma-Aminobutyric Acid; Histidine; Inhibitory Postsynaptic Potentials; Isoflurane; Leucine; Mice; Mice, Transgenic; Mutation; Neural Inhibition; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Pyridazines; Receptors, GABA-A; Serine; Thalamus; Time Factors | 2009 |
Crystal structure of Tk-subtilisin folded without propeptide: requirement of propeptide for acceleration of folding.
Topics: Alanine; Archaeal Proteins; Calcium; Crystallography, X-Ray; Enzyme Precursors; Peptide Fragments; Protein Conformation; Protein Folding; Serine; Subtilisin; Subtilisins; Thermococcus | 2008 |
Purification and gene cloning of alpha-methylserine aldolase from Ralstonia sp. strain AJ110405 and application of the enzyme in the synthesis of alpha-methyl-L-serine.
Topics: Alanine; Amaranthaceae; Bacterial Proteins; Cloning, Molecular; Comamonadaceae; Dimerization; Enzyme Inhibitors; Enzyme Stability; Escherichia coli; Formaldehyde; Fructose-Bisphosphate Aldolase; Gene Expression; Hydrogen-Ion Concentration; Molecular Weight; Protein Subunits; Ralstonia; Recombinant Proteins; Serine; Substrate Specificity; Temperature | 2008 |
Functional evaluation of serine 252 of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Catalysis; Chromatography, Gel; Circular Dichroism; Consensus Sequence; Gene Expression; Kinetics; Molecular Sequence Data; Oxaloacetates; Phosphoenolpyruvate Carboxykinase (ATP); Plasmids; Protein Structure, Secondary; Recombinant Proteins; Saccharomyces cerevisiae; Serine; Spectrometry, Fluorescence | 2009 |
Phosphorylation of DeltaFosB mediates its stability in vivo.
Topics: Alanine; Animals; Aspartic Acid; Brain; Cocaine; Dopamine Uptake Inhibitors; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Mutation; Phosphorylation; Proto-Oncogene Proteins c-fos; Serine; Time Factors | 2009 |
Regulated movement of CD4 in and out of the immunological synapse.
Topics: Alanine; Amino Acid Substitution; Animals; CD4 Antigens; Cell Proliferation; Cells, Cultured; Cytokines; Genetic Vectors; Immunological Synapses; Isoenzymes; Lymphocyte Activation; Mice; Mice, Knockout; Mice, Transgenic; Phosphorylation; Protein Kinase C; Protein Kinase C-theta; Protein Transport; Retroviridae; Serine; T-Lymphocytes | 2008 |
Mutation of critical serine residues in HIV-1 matrix result in an envelope incorporation defect which can be rescued by truncation of the gp41 cytoplasmic tail.
Topics: Alanine; Amino Acid Substitution; Cell Membrane; Detergents; HIV Envelope Protein gp41; HIV-1; Models, Molecular; Mutation; Peptide Fragments; Protein Conformation; Sequence Deletion; Serine; Viral Envelope Proteins; Viral Matrix Proteins; Virion | 2009 |
Sequence specificity of the PHSRN peptide from fibronectin on corneal epithelial migration.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Movement; Cornea; DNA Mutational Analysis; Epithelial Cells; Fibronectins; Humans; Peptide Fragments; Rabbits; Serine | 2009 |
D-serine induces lipid and protein oxidative damage and decreases glutathione levels in brain cortex of rats.
Topics: Alanine; Analysis of Variance; Animals; Antioxidants; Cerebral Cortex; Glutathione; Lipid Peroxidation; Luminescence; Oxidants; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Serine; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances; Threonine | 2009 |
Aminoacyl-tRNA recognition by the FemXWv transferase for bacterial cell wall synthesis.
Topics: Alanine; Bacteria; Cell Wall; Glycine; Nitrogenous Group Transferases; RNA, Transfer, Ala; RNA, Transfer, Amino Acyl; Serine; Stereoisomerism; Substrate Specificity; Uridine Diphosphate N-Acetylmuramic Acid | 2009 |
Phosphorylation of highly conserved neurofilament medium KSP repeats is not required for myelin-dependent radial axonal growth.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Axons; Conserved Sequence; Gene Knock-In Techniques; Lysine; Mice; Mice, Neurologic Mutants; Molecular Sequence Data; Myelin Sheath; Nerve Crush; Neural Pathways; Neurofilament Proteins; Phosphorylation; Proline; Repetitive Sequences, Amino Acid; Serine | 2009 |
Inoculation of sugarcane with Pantoea sp. increases amino acid contents in shoot tissues; serine, alanine, glutamine and asparagine permit concomitantly ammonium excretion and nitrogenase activity of the bacterium.
Topics: Alanine; Amino Acids; Asparagine; Bacterial Proteins; Glutamine; Nitrogenase; Pantoea; Quaternary Ammonium Compounds; Saccharum; Serine | 2009 |
Functional characterization of the human organic cation transporter 2 variant p.270Ala>Ser.
Topics: Alanine; Amino Acid Substitution; Biological Transport; Cell Line; Genetic Variation; Humans; Kidney; Metabolic Clearance Rate; Metformin; Organic Cation Transport Proteins; Organic Cation Transporter 1; Protein Conformation; Protein Isoforms; Serine; Subcellular Fractions | 2009 |
Crystal structures of intermediates in the nitroalkane oxidase reaction.
Topics: Alanine; Amino Acid Substitution; Catalysis; Crystallization; Crystallography, X-Ray; Dioxygenases; Ethane; Fungal Proteins; Fusarium; Kinetics; Microspectrophotometry; Mutagenesis, Site-Directed; Nitroparaffins; Serine; Substrate Specificity | 2009 |
Functional characterization of the thylakoid Ndh complex phosphorylation by site-directed mutations in the ndhF gene.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Chlorophyll; Genes, Plant; Genetic Vectors; Molecular Sequence Data; Mutagenesis, Site-Directed; Nicotiana; Phosphorylation; Photosynthesis; Plants, Genetically Modified; Sequence Analysis, DNA; Serine; Thylakoids | 2009 |
Fructose and glucose mediates enterotoxin production and anaerobic metabolism of Bacillus cereus ATCC14579(T).
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Bacillus cereus; Carbohydrates; Culture Media; Enterotoxins; Fermentation; Fructose; Glucose; Glutamic Acid; Polymerase Chain Reaction; RNA, Bacterial; RNA, Ribosomal, 16S; Serine | 2009 |
Release of endogenous amino acids from the hippocampus and brain stem from developing and adult mice in ischemia.
Topics: Aging; Alanine; Animals; Aspartic Acid; Brain Ischemia; Brain Stem; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Male; Mice; Potassium; Serine; Taurine; Threonine | 2009 |
Multifunctional role of His159in the catalytic reaction of serine palmitoyltransferase.
Topics: Alanine; Amino Acid Substitution; Apoproteins; Binding Sites; Catalysis; Histidine; Kinetics; Palmitoyl Coenzyme A; Polymerase Chain Reaction; Recombinant Proteins; Serine; Serine C-Palmitoyltransferase; Substrate Specificity | 2009 |
Growth factor-dependent trafficking of cerebellar NMDA receptors via protein kinase B/Akt phosphorylation of NR2C.
Topics: 14-3-3 Proteins; Alanine; Animals; Biotinylation; Cell Line, Transformed; Cells, Cultured; Cerebellum; Dendrites; Excitatory Amino Acid Antagonists; Gene Expression; Green Fluorescent Proteins; Hippocampus; Humans; Immunoprecipitation; In Vitro Techniques; Insulin-Like Growth Factor I; Luminescent Proteins; Mice; Mutation; N-Methylaspartate; Neurons; Oncogene Protein v-akt; Phosphorylation; Protein Structure, Tertiary; Protein Transport; Proto-Oncogene Proteins c-akt; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Transfection; Valine | 2009 |
Enantiospecific adsorption of amino acids on hydroxylated quartz (0001).
Topics: Adsorption; Alanine; Amino Acids; Cysteine; Glycine; Hydrogen Bonding; Hydroxylation; Models, Molecular; Molecular Conformation; Quantum Theory; Quartz; Serine; Stereoisomerism | 2009 |
Phosphorylation of ATXN1 at Ser776 in the cerebellum.
Topics: Alanine; Amino Acid Sequence; Animals; Ataxin-1; Ataxins; Cerebellum; Enzyme Stability; Humans; Mice; Mice, Inbred AKR; Mice, Inbred C57BL; Mice, Transgenic; Molecular Sequence Data; Nerve Tissue Proteins; Nuclear Proteins; Phosphorylation; Point Mutation; Proto-Oncogene Proteins c-akt; Purkinje Cells; Serine | 2009 |
Alpha-synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of Parkinson disease.
Topics: Alanine; alpha-Synuclein; Animals; Aspartic Acid; Basal Ganglia; Cell Count; Dependovirus; Disease Models, Animal; Dopamine; Green Fluorescent Proteins; Humans; Mutation; Nerve Tissue Proteins; Parkinson Disease; Phosphorylation; Rats; Rats, Sprague-Dawley; Serine; Substantia Nigra; Tyrosine 3-Monooxygenase | 2009 |
Relative contributions of cystathionine beta-synthase and gamma-cystathionase to H2S biogenesis via alternative trans-sulfuration reactions.
Topics: Alanine; Chromatography, High Pressure Liquid; Computer Simulation; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Humans; Hydrogen Sulfide; Kinetics; Mass Spectrometry; Models, Biological; Models, Chemical; Molecular Conformation; Serine; Sulfides; Sulfur | 2009 |
Determination of D-serine and D-alanine in the tissues and physiological fluids of mice with various D-amino-acid oxidase activities using two-dimensional high-performance liquid chromatography with fluorescence detection.
Topics: Alanine; Animals; Body Fluids; Brain Chemistry; Chromatography, High Pressure Liquid; D-Amino-Acid Oxidase; Male; Mice; Mice, Transgenic; Serine | 2009 |
Interactions across the interface contribute the stability of homodimeric 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); Alanine; Amino Acid Sequence; Catalysis; Dimerization; Dose-Response Relationship, Drug; Enzyme Stability; Escherichia coli; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Protein Folding; Serine; Structural Homology, Protein; Substrate Specificity; Temperature; Transformation, Genetic; Urea | 2009 |
PACS-1 mediates phosphorylation-dependent ciliary trafficking of the cyclic-nucleotide-gated channel in olfactory sensory neurons.
Topics: Alanine; Animals; Casein Kinase II; Cell Line, Transformed; Cilia; Cyclic Nucleotide-Gated Cation Channels; Dogs; Enzyme Inhibitors; Green Fluorescent Proteins; Humans; Immunoprecipitation; Mice; Mice, Transgenic; Mutation; Olfactory Mucosa; Phosphorylation; Protein Subunits; Protein Transport; RNA Interference; RNA, Messenger; Sensory Receptor Cells; Serine; Transfection; Triazoles; Vesicular Transport Proteins | 2009 |
Mmp-20 and Klk4 cleavage site preferences for amelogenin sequences.
Topics: Alanine; Amelogenesis; Amelogenin; Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dental Enamel; Dental Enamel Proteins; Electrophoresis, Polyacrylamide Gel; Histidine; Kallikreins; Matrix Metalloproteinase 20; Proline; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Swine; Tandem Mass Spectrometry; Tryptophan | 2009 |
Blockade of Hsp20 phosphorylation exacerbates cardiac ischemia/reperfusion injury by suppressed autophagy and increased cell death.
Topics: Alanine; Animals; Apoptosis; Autophagy; Base Sequence; Disease Models, Animal; Heart Failure; HSP20 Heat-Shock Proteins; Humans; Male; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Myocardial Contraction; Myocardium; Necrosis; Phosphorylation; Recovery of Function; Reperfusion Injury; Serine; Sirolimus; Time Factors; Ventricular Function, Left; Ventricular Pressure | 2009 |
AMINO ACID COMPOSITION OF HIGHLY PURIFIED VIRAL PARTICLES OF INFLUENZA A AND B.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Humans; Influenza, Human; Isoleucine; Leucine; Lysine; Methionine; Orthomyxoviridae; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine; Virion | 1947 |
Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster.
Topics: Acetylation; Alanine; Animals; Animals, Genetically Modified; Binding Sites; Blotting, Western; Carboxy-Lyases; Cell Line; Databases, Protein; Drosophila melanogaster; Drosophila Proteins; HeLa Cells; Humans; Immunoprecipitation; Mass Spectrometry; Mutation; Protein Biosynthesis; Protein Processing, Post-Translational; Serine; Threonine; Transgenes | 2009 |
Assay of alanine:glyoxylate aminotransferase in human liver by its serine: glyoxylate aminotransferase activity.
Topics: Alanine; Animals; Biological Assay; Humans; Liver; Pyridoxal Phosphate; Serine; Tissue Extracts; Transaminases | 2009 |
Conformational effects of the non-natural alpha-methylserine on small peptides and glycopeptides.
Topics: Alanine; Amides; Amino Acid Sequence; Glycopeptides; Glycosylation; Molecular Dynamics Simulation; Molecular Sequence Data; Peptides; Protein Conformation; Serine; Solvents; Threonine; Water | 2009 |
The TGL2 gene of Saccharomyces cerevisiae encodes an active acylglycerol lipase located in the mitochondria.
Topics: Alanine; Cerulenin; Fatty Acids; Fungal Proteins; Hydrolysis; Lipase; Lipids; Mitochondria; Mitosis; Mutation; Oleic Acid; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Saccharomyces cerevisiae; Serine; Substrate Specificity | 2010 |
Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Topics: Alanine; Alanine-tRNA Ligase; Aspartic Acid; Catalytic Domain; Crystallization; Escherichia coli; Kinetics; Models, Molecular; Mutation; Protein Biosynthesis; Protein Conformation; RNA, Transfer, Ala; Serine; Structure-Activity Relationship | 2009 |
Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amyloid; Animals; Aspartic Acid; Disease Models, Animal; Gene Expression Regulation; Genetic Predisposition to Disease; Humans; Huntingtin Protein; Huntington Disease; Mice; Mice, Transgenic; Molecular Weight; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Nuclear Proteins; Phenotype; Protein Structure, Tertiary; Serine; Trinucleotide Repeat Expansion | 2009 |
Over-expression, purification and characterization of an Asc-1 homologue from Gloeobacter violaceus.
Topics: Alanine; Biological Transport; Cysteine; Humans; Membrane Transport Proteins; Protein Structure, Secondary; Serine | 2010 |
N-terminal acetylation of cellular proteins creates specific degradation signals.
Topics: Acetylation; Alanine; Amino Acid Sequence; Cysteine; Half-Life; Methionine; Protein Stability; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity; Ubiquitin-Protein Ligases; Ubiquitination; Valine | 2010 |
An improved procedure for the synthesis of dehydroamino acids and dehydropeptides from the carbonate derivatives of serine and threonine using tetrabutylammonium fluoride.
Topics: Alanine; Carbonates; gamma-Aminobutyric Acid; Peptides; Quaternary Ammonium Compounds; Serine; Threonine | 2010 |
Acute in vivo genetic rescue demonstrates that phosphorylation of RIM1alpha serine 413 is not required for mossy fiber long-term potentiation.
Topics: 14-3-3 Proteins; Alanine; Animals; Animals, Newborn; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Green Fluorescent Proteins; GTP-Binding Proteins; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mossy Fibers, Hippocampal; Mutation; Phosphorylation; Protein Binding; Rats; Serine; Statistics, Nonparametric; Transduction, Genetic | 2010 |
Cysteine as a modulator residue in the active site of xenobiotic reductase A: a structural, thermodynamic and kinetic study.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Coumarins; Cysteine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Protein Conformation; Pseudomonas putida; Serine; Substrate Specificity; Thermodynamics; Xenobiotics | 2010 |
Anaerobic sulfatase-maturating enzyme--a mechanistic link with glycyl radical-activating enzymes?
Topics: Alanine; Anaerobiosis; Binding Sites; Catalysis; Cysteine; Electron Spin Resonance Spectroscopy; Eukaryota; Glycine; Iron-Sulfur Proteins; Oxidation-Reduction; S-Adenosylmethionine; Serine; Substrate Specificity; Sulfatases | 2010 |
A comparative study of the metabolism of alpha-alanine, beta-alanine, serine, and isoserine; absorption from the gastrointestinal tract.
Topics: Alanine; Amino Acids; beta-Alanine; Gastrointestinal Tract; Serine | 1947 |
A comparative study of the metabolism of alpha-alanine, beta-alanine, serine, and isoserine; glycogen content of the liver after oral administration of the amino acids.
Topics: Administration, Oral; Alanine; Amino Acids; beta-Alanine; Glycogen; Liver; Serine | 1947 |
Computational modelling of amino acid transfer interactions in the placenta.
Topics: Alanine; Amino Acid Transport Systems; Amino Acids; Biological Transport; Computer Simulation; Female; Fetus; Glycine; Humans; Kinetics; Maternal-Fetal Exchange; Placenta; Pregnancy; Serine; Trophoblasts | 2010 |
Manipulation of thiocillin variants by prepeptide gene replacement: structure, conformation, and activity of heterocycle substitution mutants.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Bacillus cereus; Cysteine; Gene Knockout Techniques; Molecular Sequence Data; Multigene Family; Mutation; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Conformation; Serine | 2010 |
A disease-causing mutation in the active site of serine palmitoyltransferase causes catalytic promiscuity.
Topics: Alanine; Animals; Biocatalysis; Catalytic Domain; CHO Cells; Cricetinae; Cricetulus; Extracellular Space; Hereditary Sensory and Autonomic Neuropathies; Humans; Isoenzymes; Kinetics; Mice; Mutation; Protein Multimerization; Protein Structure, Quaternary; Serine; Serine C-Palmitoyltransferase; Sphingosine; Substrate Specificity | 2010 |
Electron attachment to amino acid clusters in helium nanodroplets: glycine, alanine, and serine.
Topics: Alanine; Electrons; Glycine; Helium; Nanostructures; Serine; Temperature | 2010 |
The clinical spectrum of multiple endocrine neoplasia type 2a caused by the rare intracellular RET mutation S891A.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Alanine; Amino Acid Substitution; Carcinoma, Medullary; Gene Frequency; Genetic Association Studies; Humans; Middle Aged; Multiple Endocrine Neoplasia Type 2a; Phenotype; Pheochromocytoma; Point Mutation; Proto-Oncogene Proteins c-ret; Serine; Thyroid Neoplasms; Young Adult | 2010 |
Purification and biochemical characterization of Mur ligases from Staphylococcus aureus.
Topics: Adenosine Triphosphate; Alanine; Bacterial Proteins; Diaminopimelic Acid; Escherichia coli; Genetic Complementation Test; Glycine; Hydrogen-Ion Concentration; Kinetics; Ligases; Mutation; Oligopeptides; Peptidoglycan; Recombinant Proteins; Serine; Staphylococcus aureus; Substrate Specificity; Temperature | 2010 |
Conformation dependence of the DαDα stretch mode in peptides: Side-chain influence in dipeptide structures.
Topics: Alanine; Dipeptides; Glycine; Isoleucine; Leucine; Models, Molecular; Molecular Conformation; Peptides; Phenylalanine; Protein Conformation; Serine; Valine; Water | 2010 |
Polar groups in membrane channels: consequences of replacing alanines with serines in membrane-spanning gramicidin channels.
Topics: Alanine; Chromatography, Gel; Circular Dichroism; Electrophysiology; Gramicidin; Ion Channels; Protein Folding; Serine | 2010 |
Clinical presentations and skin denervation in amyloid neuropathy due to transthyretin Ala97Ser.
Topics: Aged; Alanine; Amino Acid Substitution; Amyloid Neuropathies; Amyloid Neuropathies, Familial; Female; Humans; Male; Middle Aged; Mutation, Missense; Prealbumin; Serine; Skin | 2010 |
Deoxysphingoid bases as plasma markers in diabetes mellitus.
Topics: Aged; Alanine; Biomarkers; Body Mass Index; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease Progression; Female; Humans; Lipoproteins; Male; Middle Aged; Serine; Sphingolipids; Sphingosine; Statistics as Topic | 2010 |
Deficiency in L-serine deaminase interferes with one-carbon metabolism and cell wall synthesis in Escherichia coli K-12.
Topics: Alanine; Amino Acids; Carbon; Cell Wall; Culture Media; Escherichia coli K12; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Glucose; Hypoxanthine; L-Serine Dehydratase; Mutation; Promoter Regions, Genetic; Serine | 2010 |
Effects of amino acid transport limitations on cultured hepatocytes.
Topics: Alanine; Albumins; Amino Acids; Animals; Biological Transport; Cells, Cultured; Glutamine; Hepatocytes; Male; Models, Biological; Rats; Serine; Urea | 2010 |
Simultaneous two-dimensional HPLC determination of free D-serine and D-alanine in the brain and periphery of mutant rats lacking D-amino-acid oxidase.
Topics: Alanine; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; D-Amino-Acid Oxidase; Disease Models, Animal; Kidney; Male; Pancreas; Pituitary Gland; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Rats, Transgenic; Rats, Wistar; Regression Analysis; Reproducibility of Results; Serine; Stereoisomerism | 2011 |
Acquisition of Raman spectra of amino acids using portable instruments: outdoor measurements and comparison.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; beta-Alanine; Glutamic Acid; Glutamine; Glycine; Methionine; Proline; Research Design; Robotics; Serine; Spectrum Analysis, Raman; Transportation; Tryptophan; Tyrosine; Workplace | 2010 |
Probing the active site of the deoxynucleotide N-hydrolase Rcl encoded by the rat gene c6orf108.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Catalysis; Catalytic Domain; Glutamic Acid; Kinetics; Molecular Sequence Data; N-Glycosyl Hydrolases; Nuclear Proteins; Protein Binding; Proto-Oncogene Proteins; Rats; Sequence Homology, Amino Acid; Serine | 2010 |
Variations of some constituents in the urine of rats receiving dl-serine and dl-alanine.
Topics: Alanine; Amino Acids; Animals; Dietary Proteins; Rats; Serine; Urine | 1945 |
Novel oxidative modifications in redox-active cysteine residues.
Topics: Alanine; Amino Acid Sequence; Animals; Catalytic Domain; Cysteine; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); HEK293 Cells; Humans; Mass Spectrometry; Mice; Mitochondrial Proteins; Molecular Sequence Data; Mutant Proteins; Nucleoside-Diphosphate Kinase; Oxidation-Reduction; Peptides; Peroxiredoxin VI; Protein Processing, Post-Translational; Recombinant Proteins; Serine; Sulfenic Acids; Sulfinic Acids | 2011 |
PDZK1 binding and serine phosphorylation regulate subcellular trafficking of organic anion transport protein 1a1.
Topics: Adenosine Triphosphate; Alanine; Animals; Carrier Proteins; Cell Line, Tumor; Cell Membrane; Cytoplasmic Vesicles; Glutamic Acid; HEK293 Cells; Hepatocytes; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Mutagenesis, Site-Directed; Mutation; Organic Anion Transporters; Phosphorylation; Protein Binding; Protein Transport; Rats; Recombinant Fusion Proteins; Serine; Time Factors; Transfection | 2011 |
Mutations in the transmembrane domain M3 generate spontaneously open orphan glutamate δ1 receptor.
Topics: Alanine; Animals; Calcium Signaling; Cell Membrane; Conserved Sequence; Female; Ion Channel Gating; Mice; Mice, Neurologic Mutants; Mutagenesis; Mutant Chimeric Proteins; Protein Conformation; Protein Structure, Tertiary; Receptors, Glutamate; Serine; Xenopus laevis | 2011 |
Regulation of the incorporation of tissue factor into microparticles by serine phosphorylation of the cytoplasmic domain of tissue factor.
Topics: Alanine; Apoptosis; Aspartic Acid; Blotting, Western; Cell-Derived Microparticles; Cells, Cultured; Humans; Oligopeptides; Phosphorylation; Serine; Signal Transduction; Thromboplastin | 2011 |
Water permeation dynamics of AqpZ: a tale of two states.
Topics: Alanine; Amino Acid Substitution; Aquaporins; Arginine; Biological Transport; Cell Membrane; Cell Membrane Permeability; Escherichia coli; Escherichia coli Proteins; Models, Molecular; Molecular Dynamics Simulation; Mutation; Osmosis; Osmotic Pressure; Protein Conformation; Serine; Water | 2011 |
Solomonamides A and B, new anti-inflammatory peptides from Theonella swinhoei.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Edema; Marine Biology; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Serine; Theonella | 2011 |
The role of the disulfide bridge in the stability and structural integrity of ovalbumin evaluated by site-directed mutagenesis.
Topics: Alanine; Animals; Chickens; Circular Dichroism; Cloning, Molecular; Disulfides; Escherichia coli; Gene Expression; Hydrogen-Ion Concentration; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Ovalbumin; Pancreatic Elastase; Peptide Fragments; Protein Conformation; Protein Denaturation; Protein Stability; Recombinant Proteins; Serine; Spectrometry, Fluorescence; Temperature | 2011 |
Role of complement factor H I62V and age-related maculopathy susceptibility 2 A69S variants in the clinical expression of polypoidal choroidal vasculopathy.
Topics: Adult; Age of Onset; Alanine; Choroid; Choroid Diseases; Choroidal Neovascularization; Chromatography; Complement Factor H; Cross-Sectional Studies; Fundus Oculi; Gene Frequency; Genetic Variation; Genotype; Heterozygote; Homozygote; Humans; Incidence; Isoleucine; Phenotype; Polyps; Proteins; Retinal Detachment; Retinal Hemorrhage; Retinal Pigment Epithelium; Serine; Valine; Vascular Diseases | 2011 |
Btk regulation in human and mouse B cells via protein kinase C phosphorylation of IBtkγ.
Topics: Adaptor Proteins, Signal Transducing; Agammaglobulinaemia Tyrosine Kinase; Alanine; Amino Acid Substitution; Animals; Carrier Proteins; Cells; Cells, Cultured; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Mutation, Missense; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Serine; Signal Transduction | 2011 |
Effect of the quality of dietary amino acids composition on the urea synthesis in rats.
Topics: Alanine; Amino Acids; Animals; Caseins; Dietary Proteins; Egg Proteins; Glutamates; Glutamic Acid; Glutens; Liver; Male; Methionine; Ornithine; Protein Biosynthesis; Rats; Rats, Wistar; Serine; Urea | 2011 |
Impact of site-specific N-glycosylation on cellular secretion, activity and specific activity of the plasma phospholipid transfer protein.
Topics: Alanine; Amino Acid Substitution; Animals; Binding Sites; Blotting, Western; Carbohydrates; CHO Cells; Cricetinae; Cricetulus; Culture Media, Conditioned; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Glycosylation; Humans; Mutagenesis, Site-Directed; Mutant Proteins; Mutation; Phospholipid Transfer Proteins; Serine | 2011 |
Casein kinase-2α1 induces hypertrophic response by phosphorylation of histone deacetylase 2 S394 and its activation in the heart.
Topics: Alanine; Animals; Cardiomegaly; Cardiomyopathy, Hypertrophic; Casein Kinase II; Enzyme Activation; Heart Ventricles; Histone Deacetylase 2; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphorylation; Serine | 2011 |
Synthesis, transport and antiviral activity of Ala-Ser and Val-Ser prodrugs of cidofovir.
Topics: Administration, Oral; Alanine; Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Molecular Structure; Organophosphonates; Peptides; Prodrugs; Rats; Serine; Valine | 2011 |
Monitoring selected hydrogen bonds in crystal hydrates of amino acid salts: combining variable-temperature single-crystal X-ray diffraction and polarized Raman spectroscopy.
Topics: Alanine; Amino Acids; Crystallography, X-Ray; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Oxalates; Salts; Serine; Spectrum Analysis, Raman; Temperature | 2011 |
Occludin localizes to centrosomes and modifies mitotic entry.
Topics: Alanine; Animals; Centrosome; Chlorocebus aethiops; COS Cells; Dogs; Gene Expression Regulation; Immunohistochemistry; Membrane Proteins; Microscopy, Fluorescence; Mitosis; Occludin; Phosphorylation; Serine; Subcellular Fractions; Tubulin | 2011 |
A convenient route to optically pure α-alkyl-β-(sec-amino)alanines.
Topics: Alanine; Cyclization; Lactones; Morpholines; Piperidines; Pyrrolidines; Serine; Stereoisomerism | 2012 |
An inserted α/β subdomain shapes the catalytic pocket of Lactobacillus johnsonii cinnamoyl esterase.
Topics: Alanine; Binding Sites; Biocatalysis; Carboxylic Ester Hydrolases; Catalytic Domain; Humans; Hydrolysis; Kinetics; Lactobacillus; Models, Molecular; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Mutant Proteins; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Structural Homology, Protein; Structure-Activity Relationship; Substrate Specificity; X-Ray Diffraction | 2011 |
Investigation of biomolecules trapped in fluid inclusions inside halite crystals by Raman spectroscopy.
Topics: Alanine; Amino Acids; beta-Alanine; Crystallization; Exobiology; Extraterrestrial Environment; gamma-Aminobutyric Acid; Glycine; Serine; Spectrum Analysis, Raman | 2011 |
Analgesic tolerance to high-efficacy agonists but not to morphine is diminished in phosphorylation-deficient S375A μ-opioid receptor knock-in mice.
Topics: Alanine; Analgesics, Opioid; Animals; Drug Tolerance; Gene Knock-In Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Morphine; Pain Measurement; Phosphorylation; Receptors, Opioid, mu; Serine | 2011 |
Improving a natural CaMKII inhibitor by random and rational design.
Topics: Alanine; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Drug Design; Molecular Sequence Data; Mutagenesis; Mutation; Peptides; Phosphorylation; Protein Kinase Inhibitors; Serine; Solutions; Substrate Specificity | 2011 |
Synthesis of analogues of ochratoxin A.
Topics: Alanine; Magnetic Resonance Spectroscopy; Molecular Structure; Ochratoxins; Serine; Triazoles | 2012 |
Hippocampal GluA1-containing AMPA receptors mediate context-dependent sensitization to morphine.
Topics: Alanine; Analysis of Variance; Animals; Behavior, Animal; Carrier Proteins; Cell Cycle Proteins; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Gene Transfer Techniques; Green Fluorescent Proteins; Guanylate Kinases; Hippocampus; In Situ Nick-End Labeling; Long-Term Potentiation; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Motor Activity; Mutation; Narcotics; Nuclear Proteins; Phosphorylation; Protein Transport; Random Allocation; Receptors, AMPA; Serine; Subcellular Fractions | 2011 |
Agonist-induced PKC phosphorylation regulates GluK2 SUMOylation and kainate receptor endocytosis.
Topics: Alanine; Amino Acid Substitution; Animals; Blotting, Western; Cells, Cultured; Chlorocebus aethiops; COS Cells; Endocytosis; GluK2 Kainate Receptor; HEK293 Cells; Humans; Kainic Acid; Luminescent Proteins; Microscopy, Confocal; Mutation; Neurons; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Receptors, Kainic Acid; Serine; SUMO-1 Protein; Sumoylation | 2011 |
The ATP-sensitive K(+) channel ABCC8 S1369A type 2 diabetes risk variant increases MgATPase activity.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Amino Acid Substitution; ATP-Binding Cassette Transporters; Cells, Cultured; Diabetes Mellitus, Type 2; Enzyme Activation; Genetic Predisposition to Disease; Humans; KATP Channels; Models, Molecular; Polymorphism, Single Nucleotide; Potassium Channels, Inwardly Rectifying; Protein Structure, Tertiary; Receptors, Drug; Risk Factors; Serine; Sulfonylurea Receptors; Transfection | 2012 |
[Determination of amino acid contents in cottonseeds using near infrared reflectance spectroscopy].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Calibration; Cottonseed Oil; Cystine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Spectroscopy, Near-Infrared; Threonine; Tyrosine; Valine | 2011 |
Cdc5-dependent asymmetric localization of bfa1 fine-tunes timely mitotic exit.
Topics: Alanine; Anaphase; Aspartic Acid; Cell Cycle; Cell Cycle Proteins; Cytoskeletal Proteins; GTPase-Activating Proteins; Metaphase; Mitosis; Mutation; Phosphorylation; Protein Interaction Domains and Motifs; Protein Kinases; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Spindle Apparatus | 2012 |
Photostability of Iiovaline and its precursor 5-Ethyl-5- methylhydantoin exposed to simulated space radiations.
Topics: Alanine; Aspartic Acid; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Gamma Rays; Hydantoins; Photolysis; Serine; Ultraviolet Rays; Valine | 2012 |
The p85α regulatory subunit of PI3K mediates cAMP-PKA and retinoic acid biological effects on MCF7 cell growth and migration.
Topics: Alanine; Animals; Antineoplastic Agents; Aspartic Acid; Breast Neoplasms; Cattle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Class Ia Phosphatidylinositol 3-Kinase; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Female; Humans; Mutation; Neoplasm Invasiveness; Phosphorylation; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Serine; Signal Transduction; src Homology Domains; Time Factors; Transfection; Tretinoin | 2012 |
RASSF1A Ala133Ser polymorphism is associated with increased susceptibility to hepatocellular carcinoma in a Turkish population.
Topics: Aged; Alanine; Amino Acid Substitution; Carcinoma, Hepatocellular; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Liver Neoplasms; Male; Middle Aged; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Serine; Tumor Suppressor Proteins; Turkey | 2012 |
Conformational change in rhomboid protease GlpG induced by inhibitor binding to its S' subsites.
Topics: Alanine; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; DNA-Binding Proteins; Endopeptidases; Escherichia coli Proteins; Membrane Proteins; Models, Molecular; Organophosphorus Compounds; Protease Inhibitors; Protein Conformation; Protein Structure, Tertiary; Serine | 2012 |
The three-dimensional structural basis of type II hyperprolinemia.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acid Substitution; Animals; Catalytic Domain; Crystallography, X-Ray; Humans; Hydrogen Bonding; Leucine; Mice; Mutation; NAD; Protein Conformation; Protein Folding; Serine | 2012 |
N-terminal phosphorylation of protein phosphatase 2A/Bβ2 regulates translocation to mitochondria, dynamin-related protein 1 dephosphorylation, and neuronal survival.
Topics: Alanine; Amino Acid Substitution; Animals; Apoptosis; Cell Survival; Cells, Cultured; COS Cells; Dynamins; Green Fluorescent Proteins; GTP Phosphohydrolases; HEK293 Cells; HeLa Cells; Hippocampus; Humans; Immunoblotting; Microscopy, Fluorescence; Microtubule-Associated Proteins; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Mutation; Nerve Tissue Proteins; Neurons; Phosphorylation; Protein Phosphatase 2; Protein Transport; Serine | 2013 |
Phosphorylation and activation of nuclear Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP-N/PPM1E) by Ca2+/calmodulin-dependent protein kinase I (CaMKI).
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Cell Line, Tumor; Enzyme Activation; Mice; Molecular Sequence Data; Mutation; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2C; Rats; Recombinant Proteins; Serine | 2012 |
Constitutively active mutant gives novel insights into the mechanism of bitter taste receptor activation.
Topics: Alanine; Amino Acids; Calcium; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Hydrogen Bonding; Models, Molecular; Mutation; Quaternary Ammonium Compounds; Quinine; Receptors, G-Protein-Coupled; Serine; Signal Transduction; Stimulation, Chemical; Taste; Transfection | 2012 |
Alanine or aspartic acid substitutions at serine23/24 of cardiac troponin I decrease thin filament activation, with no effect on crossbridge detachment kinetics.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Substitution; Animals; Aspartic Acid; Calcium; Cyclic AMP-Dependent Protein Kinases; Kinetics; Male; Muscle Contraction; Muscle Fibers, Skeletal; Myocardium; Myofibrils; Phosphorylation; Rats; Serine; Troponin I | 2012 |
Rescue of a pathogenic mutant human glucagon receptor by pharmacological chaperones.
Topics: Alanine; Asparagine; Cell Membrane; Curcumin; Cyclic AMP; Drug Design; Glucagon; Green Fluorescent Proteins; HEK293 Cells; Humans; Molecular Chaperones; Mutation; Pancreatic Neoplasms; Protein Transport; Pyridines; Pyrroles; Receptors, Glucagon; Serine; Thapsigargin | 2012 |
The recent evolution of a symbiotic ion channel in the legume family altered ion conductance and improved functionality in calcium signaling.
Topics: Alanine; Amino Acid Substitution; Biological Evolution; Calcium Signaling; Cell Line; Electrophysiological Phenomena; Evolution, Molecular; Fabaceae; Genetic Complementation Test; Humans; Ion Channels; Lotus; Medicago truncatula; Molecular Sequence Data; Mutation; Mycorrhizae; Phylogeny; Plant Proteins; Potassium; Serine; Symbiosis | 2012 |
Screening for POLG W748S and A467T mutations in ataxia patients from Spain.
Topics: Adult; Age of Onset; Aged; Alanine; Ataxia; DNA Polymerase gamma; DNA-Directed DNA Polymerase; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Male; Middle Aged; Mutation; Polymorphism, Single Nucleotide; Serine; Spain; Threonine; Tryptophan; Young Adult | 2012 |
Ser(262) determines the chloride-dependent colour tuning of a new halorhodopsin from Haloquadratum walsbyi.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Archaeal Proteins; Chlorides; Color; Escherichia coli; Haloarcula marismortui; Halobacteriaceae; Halorhodopsins; Light; Molecular Sequence Data; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Spectrophotometry, Ultraviolet | 2012 |
Selective lighting up of segments around Gly, Ala and Ser/Thr in proteins.
Topics: Alanine; Glycine; Humans; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Serine; Threonine; Ubiquitin | 2012 |
Discriminating D-amino acid-containing peptide epimers by radical-directed dissociation mass spectrometry.
Topics: Alanine; Amino Acid Sequence; Amino Acids; D-Aspartic Acid; Free Radicals; Peptides; Serine; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism | 2012 |
CREB selectively controls learning-induced structural remodeling of neurons.
Topics: Alanine; Analysis of Variance; Animals; Animals, Newborn; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Conditioning, Psychological; CREB-Binding Protein; Dendritic Spines; Doxycycline; Electroshock; Fear; Female; Gene Expression Regulation, Developmental; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurons; Phosphorylation; Serine; Silver Staining | 2012 |
Fc receptor-γ subunits with both polar or non-polar amino acids at position of T22 are capable of restoring surface expression of the high-affinity IgE receptor and degranulation in γ subunit-deficient rat basophilic leukemia cells.
Topics: Alanine; Amino Acid Substitution; Animals; Basophils; Cell Degranulation; Cell Line, Tumor; Hydrogen Bonding; Leukemia, Basophilic, Acute; Mutant Proteins; Protein Interaction Domains and Motifs; Protein Subunits; Rats; Receptors, IgE; Recombinant Proteins; Serine; Signal Transduction; Threonine; Transfection | 2013 |
Systematic identification of functional residues in mammalian histone H2AX.
Topics: Alanine; Amino Acid Motifs; Amino Acid Substitution; Cell Line; Cell Proliferation; Cell Survival; DNA Breaks, Double-Stranded; DNA Damage; DNA Repair; Gene Knockout Techniques; Histones; Humans; Intracellular Signaling Peptides and Proteins; Phosphorylation; Protein Processing, Post-Translational; Serine; Sumoylation; Tumor Suppressor p53-Binding Protein 1; Tumor Suppressor Protein p53; Ubiquitination | 2013 |
Characterization and identification of alanine to serine sequence variants in an IgG4 monoclonal antibody produced in mammalian cell lines.
Topics: Alanine; Amino Acid Sequence; Animals; Antibodies, Monoclonal; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; DNA, Complementary; Humans; Immunoglobulin G; Molecular Sequence Data; Peptide Fragments; Peptide Mapping; Serine; Tandem Mass Spectrometry; Trypsin | 2012 |
Natural templates for coiled-coil biomaterials from praying mantis egg cases.
Topics: Alanine; Amino Acid Sequence; Animals; Biocompatible Materials; Biomimetic Materials; Circular Dichroism; Escherichia coli; Female; Fibroins; Gene Library; Glutamic Acid; Hydrophobic and Hydrophilic Interactions; Lysine; Magnetic Resonance Spectroscopy; Mantodea; Molecular Sequence Data; Molecular Weight; Ovum; Protein Structure, Secondary; Recombinant Proteins; Scleroproteins; Sequence Alignment; Sequence Analysis, DNA; Serine | 2012 |
Identification of STAT2 serine 287 as a novel regulatory phosphorylation site in type I interferon-induced cellular responses.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Cell Line, Tumor; Chromatin; Dimerization; DNA, Complementary; HEK293 Cells; Humans; Interferon Type I; Interferon-alpha; Molecular Sequence Data; Mutagenesis; Phosphorylation; Plasmids; Protein Processing, Post-Translational; Sequence Homology, Amino Acid; Serine; STAT2 Transcription Factor | 2013 |
Ataxia telangiectasia mutated-dependent regulation of topoisomerase II alpha expression and sensitivity to topoisomerase II inhibitor.
Topics: Alanine; Antigens, Neoplasm; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Histone-Lysine N-Methyltransferase; Humans; Leukemia; Mutagenesis, Site-Directed; Myeloid-Lymphoid Leukemia Protein; Phosphorylation; Poly-ADP-Ribose Binding Proteins; Protein Serine-Threonine Kinases; Serine; Topoisomerase II Inhibitors; Tumor Suppressor Proteins | 2013 |
Re-introduction of transmembrane serine residues reduce the minimum pore diameter of channelrhodopsin-2.
Topics: Alanine; Amino Acid Sequence; Animals; Bacteriorhodopsins; Carrier Proteins; Cation Transport Proteins; Chlamydomonas reinhardtii; Hydrogen Bonding; Membranes; Mutation; Permeability; Protein Conformation; Serine; Xenopus laevis | 2012 |
CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo.
Topics: Alanine; Amino Acid Substitution; Cell Line; Humans; mRNA Cleavage and Polyadenylation Factors; Nuclear Proteins; Promoter Regions, Genetic; Protein Structure, Tertiary; Protein Subunits; Proto-Oncogene Proteins c-fos; Ribonucleoproteins; RNA 3' End Processing; RNA Cleavage; RNA Polymerase II; RNA Splicing; RNA, Small Nuclear; Serine; Splicing Factor U2AF; Transcription, Genetic | 2013 |
Copper(II) complexes of neurokinin A with point mutation (S5A) and products of copper-catalyzed oxidation; role of serine residue in peptides containing neurokinin A sequence.
Topics: Alanine; Animals; Chromatography, Liquid; Coordination Complexes; Copper; Histidine; Humans; Hydrogen Peroxide; Kinetics; Mass Spectrometry; Methionine; Neurokinin A; Oligopeptides; Oxidation-Reduction; Point Mutation; Protons; Serine | 2013 |
Myofilament incorporation and contractile function after gene transfer of cardiac troponin I Ser43/45Ala.
Topics: Adenoviridae; Alanine; Amino Acid Substitution; Animals; Blotting, Western; Calcium; Culture Media, Serum-Free; Endothelin-1; Female; Gene Transfer Techniques; HEK293 Cells; Humans; Immunohistochemistry; Muscle Contraction; Mutagenesis, Site-Directed; Myocytes, Cardiac; Myofibrils; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sarcomeres; Serine; Time Factors; Troponin I | 2013 |
Tamavidin 2-REV: an engineered tamavidin with reversible biotin-binding capability.
Topics: Alanine; Amino Acid Substitution; Animals; Avidin; Biotin; Carrier Proteins; Cattle; Escherichia coli; Fungal Proteins; Immobilized Proteins; Kinetics; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Stability; Recombinant Proteins; Serine; Serum Albumin, Bovine | 2013 |
Amino acid turnover by human oocytes is influenced by gamete developmental competence, patient characteristics and gonadotrophin treatment.
Topics: Age Factors; Alanine; Amino Acids; Arginine; Chorionic Gonadotropin; Chromatography, High Pressure Liquid; Female; Follicle Stimulating Hormone; Glutamic Acid; Glutamine; Gonadotropins; Humans; Infertility, Female; Isoleucine; Kinetics; Lysine; Metaphase; Oocytes; Ovulation Induction; Polycystic Ovary Syndrome; Serine; Valine | 2013 |
No correlation between plasma NMDA-related glutamatergic amino acid levels and cognitive function in medicated patients with schizophrenia.
Topics: Adolescent; Adult; Aged; Alanine; Antipsychotic Agents; Basal Ganglia Diseases; Biomarkers; Brief Psychiatric Rating Scale; Cholinergic Antagonists; Cognition Disorders; Drug Therapy, Combination; Female; Glycine; Humans; Male; Middle Aged; Neuropsychological Tests; Reference Values; Schizophrenia; Serine; Young Adult | 2012 |
Eukaryotic initiation factor 5A dephosphorylation is required for translational arrest in stationary phase cells.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Eukaryotic Translation Initiation Factor 5A; Molecular Sequence Data; Peptide Initiation Factors; Phosphorylation; Polyribosomes; Protein Biosynthesis; RNA-Binding Proteins; Serine; Trypanosoma cruzi; Tyrosine | 2013 |
Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling.
Topics: Adaptor Proteins, Signal Transducing; Alanine; Animals; Culture Media, Conditioned; Dishevelled Proteins; Gene Expression Regulation; HEK293 Cells; Humans; Mutation; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins; Rats; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Wnt Proteins; Wnt-5a Protein; Wnt3A Protein | 2013 |
Rice small C2-domain proteins are phosphorylated by calcium-dependent protein kinase.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Calcium; Cell Membrane; Cytosol; Molecular Sequence Data; Mutation; Oryza; Phospholipids; Phosphorylation; Plant Proteins; Protein Kinases; Serine | 2013 |
Mild haemophilia B from a novel missense mutation Ser350Ala of the F9 gene.
Topics: Alanine; Amino Acid Sequence; Child, Preschool; Factor IX; Female; Hemizygote; Hemophilia B; Heterozygote; Humans; Male; Molecular Sequence Data; Mutation, Missense; Partial Thromboplastin Time; Serine | 2013 |
A conserved serine residue regulates the stability of Drosophila Salvador and human WW domain-containing adaptor 45 through proteasomal degradation.
Topics: Alanine; Animals; Cell Cycle Proteins; Cell Line, Tumor; Drosophila; Drosophila Proteins; Electrophoresis, Polyacrylamide Gel; Humans; Intracellular Signaling Peptides and Proteins; Leupeptins; Mutagenesis, Site-Directed; Mutation; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Protein Stability; Proteolysis; Serine; Species Specificity; Transfection | 2013 |
Association study between FSHR Ala307Thr and Ser680Asn variants and polycystic ovary syndrome (PCOS) in Northern Chinese Han women.
Topics: Adult; Alanine; Amino Acid Substitution; Asian People; Asparagine; Case-Control Studies; China; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Geography; Humans; Mutation, Missense; Polycystic Ovary Syndrome; Polymorphism, Single Nucleotide; Receptors, FSH; Serine; Threonine | 2013 |
Sensitive D-amino acid biosensor based on oxidase/peroxidase system mediated by pentacyanoferrate-bound polymer.
Topics: Alanine; Biosensing Techniques; D-Amino-Acid Oxidase; Electrochemistry; Enzymes, Immobilized; Ferrous Compounds; Hydrogen Peroxide; Peroxidase; Polymers; Serine | 2013 |
D-amino acid aberrations in cerebrospinal fluid and plasma of smokers.
Topics: Adult; Alanine; Alcohol Drinking; Excitatory Amino Acid Agonists; Female; Glycine; Humans; Male; Proline; Self Report; Serine; Smoking; Stereoisomerism | 2013 |
Requirement of phosphorylatable endothelial nitric oxide synthase at Ser-1177 for vasoinhibin-mediated inhibition of endothelial cell migration and proliferation in vitro.
Topics: Alanine; Animals; Cattle; Cell Cycle Proteins; Cell Movement; Cell Proliferation; Cells, Cultured; Endothelium, Vascular; Humans; In Vitro Techniques; Models, Animal; Nitric Oxide Synthase Type III; Phosphorylation; Recombinant Proteins; Serine; Transfection | 2014 |
Voltage-dependent processes in the electroneutral amino acid exchanger ASCT2.
Topics: Alanine; Amino Acid Sequence; Amino Acid Transport System ASC; Animals; Binding Sites; Cysteine; HEK293 Cells; Humans; Membrane Potentials; Minor Histocompatibility Antigens; Molecular Dynamics Simulation; Molecular Sequence Data; Protein Structure, Tertiary; Rats; Serine; Sodium | 2013 |
Clinical presentation of Von Hippel Lindau syndrome type 2B associated with VHL p.A149S mutation in a large Turkish family.
Topics: Adolescent; Adult; Alanine; Amino Acid Substitution; Family; Female; Humans; Male; Middle Aged; Mutation, Missense; Pedigree; Serine; Turkey; von Hippel-Lindau Disease; Von Hippel-Lindau Tumor Suppressor Protein; Young Adult | 2014 |
Electron densities by the maximum entropy method (MEM) for various types of prior densities: a case study on three amino acids and a tripeptide.
Topics: Alanine; Entropy; Glycine; Hydrogen Bonding; Models, Molecular; Oligopeptides; Serine; X-Ray Diffraction | 2013 |
PASylation: a biological alternative to PEGylation for extending the plasma half-life of pharmaceutically active proteins.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Escherichia coli; Growth Hormone; Half-Life; Humans; Immunoglobulin Fab Fragments; Mice; Models, Molecular; Molecular Sequence Data; Peptides; Polyethylene Glycols; Proline; Protein Structure, Secondary; Recombinant Fusion Proteins; Serine | 2013 |
β-adrenergic regulation of the L-type Ca2+ channel does not require phosphorylation of α1C Ser1700.
Topics: Action Potentials; Adrenergic Agents; Alanine; Amino Acid Motifs; Animals; Calcium Channels, L-Type; Cyclic AMP-Dependent Protein Kinases; Mice; Mutation; Myocytes, Cardiac; Phosphorylation; Proteolysis; Rabbits; Serine; Threonine | 2013 |
Rapamycin enhances eIF4E phosphorylation by activating MAP kinase-interacting kinase 2a (Mnk2a).
Topics: Alanine; Amino Acid Sequence; Animals; Cell Line, Tumor; Enzyme Activation; Eukaryotic Initiation Factor-4E; Fibroblasts; Gene Expression Regulation, Enzymologic; Guanosine Triphosphate; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mice; Molecular Sequence Data; Mutation; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Serine; Sirolimus | 2013 |
Three most common nonsynonymous UGT1A6*2 polymorphisms (Thr181Ala, Arg184Ser and Ser7Ala) and therapeutic response to deferiprone in β-thalassemia major patients.
Topics: Adolescent; Alanine; Amino Acid Substitution; Arginine; beta-Thalassemia; Child; Child, Preschool; Deferiprone; Female; Gene Frequency; Genetic Association Studies; Glucuronosyltransferase; Humans; Iron Chelating Agents; Iron Overload; Isoenzymes; Male; Mutation, Missense; Polymorphism, Single Nucleotide; Pyridones; Serine; Threonine; Treatment Outcome | 2013 |
Combined effects of polymorphisms of DNA-repair protein genes and metabolic enzyme genes on the risk of cholangiocarcinoma.
Topics: Alanine; Arginine; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma; Cysteine; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; Genotype; Glutamine; Glutathione Transferase; Histidine; Humans; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Risk Assessment; Risk Factors; Serine; Valine; X-ray Repair Cross Complementing Protein 1 | 2013 |
Human protein aging: modification and crosslinking through dehydroalanine and dehydrobutyrine intermediates.
Topics: Adult; Aged, 80 and over; Alanine; Amino Acid Sequence; Aminobutyrates; Cell Nucleus; Cross-Linking Reagents; Crystallins; Glutathione; Humans; Lens, Crystalline; Middle Aged; Molecular Sequence Data; Peptides; Protein Processing, Post-Translational; Serine; Tandem Mass Spectrometry; Threonine; Time Factors | 2014 |
Detection of urinary metabolomics before and after Pringle maneuver-induced liver ischemia and reperfusion injury in rats using gas chromatography-mass spectrometry.
Topics: Alanine; Alanine Transaminase; Animals; Bilirubin; Gas Chromatography-Mass Spectrometry; Glycerophosphates; Lactic Acid; Liver; Male; Metabolome; Metabolomics; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Serine | 2013 |
Transglycosylation of engineered cyclodextrin glucanotransferases as O-glycoligases.
Topics: Alanine; Escherichia coli; Gene Expression; Glucosides; Glucosyltransferases; Glutamic Acid; Glycosylation; Kinetics; Ligases; Mutagenesis, Site-Directed; Mutation; Protein Engineering; Serine | 2014 |
Molecular characterization of an alanine-, proline-, glycine-, threonine-, and serine-rich protein of the hard tick Haemaphysalis qinghaiensis and its effect as a vaccine against tick infestation in sheep.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; DNA, Complementary; Glycine; Immunity, Active; Ixodidae; Molecular Sequence Data; Phylogeny; Proline; Rabbits; Recombinant Proteins; Sequence Analysis, DNA; Serine; Sheep; Sheep Diseases; Threonine; Tick Infestations; Vaccination; Vaccines | 2014 |
Structural and functional analysis of a FeoB A143S G5 loop mutant explains the accelerated GDP release rate.
Topics: Alanine; Amino Acid Sequence; Animals; Bacterial Proteins; Catalysis; Fluorescence; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Hydrolysis; Molecular Sequence Data; Sequence Homology, Amino Acid; Serine; Streptococcus thermophilus | 2014 |
Effects of pH and lactate on hydrogen sulfide production by oral Veillonella spp.
Topics: Alanine; Ammonia; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Hydrogen Sulfide; Hydrogen-Ion Concentration; Lactic Acid; Serine; Sulfides; Veillonella | 2014 |
Selective oxidation of D-amino acids catalyzed by oligolamellar liposomes intercalated with D-amino acid oxidase.
Topics: Alanine; Amino Acids; Animals; Catalysis; Colloids; D-Amino-Acid Oxidase; Hydrogen-Ion Concentration; Kidney; Lipid Bilayers; Liposomes; Lysosomes; Oxygen; Permeability; Phosphatidylcholines; Serine; Stereoisomerism; Substrate Specificity; Swine; Temperature | 2014 |
GABAB receptor phosphorylation regulates KCTD12-induced K⁺ current desensitization.
Topics: Alanine; Amino Acid Substitution; Animals; Cells, Cultured; CHO Cells; Cricetulus; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Hippocampus; Mice; Mice, Knockout; Neurons; Patch-Clamp Techniques; Phosphorylation; Potassium; Receptors, GABA; Receptors, GABA-B; Serine | 2014 |
Systematic tuning of heme redox potentials and its effects on O2 reduction rates in a designed oxidase in myoglobin.
Topics: Alanine; Animals; Binding Sites; Biocatalysis; Copper; Electron Transport Complex IV; Heme; Histidine; Hydrogen Bonding; Male; Models, Molecular; Myoglobin; Oxidation-Reduction; Oxygen; Protein Engineering; Serine; Spermatozoa; Whales | 2014 |
[The influence of low partial oxygen pressure on the biolodical process of mesenchymal stromal cells].
Topics: Alanine; Aspartic Acid; Cell Hypoxia; Cell Line; Collagen; Culture Media; Glutamine; Humans; Hydroxyproline; Mesenchymal Stem Cells; Oxygen; Proline; Serine | 2014 |
Correcting for the free energy costs of bond or angle constraints in molecular dynamics simulations.
Topics: Alanine; Algorithms; Energy Transfer; Ethane; Methanol; Molecular Dynamics Simulation; Molecular Structure; Oscillometry; Reproducibility of Results; Serine | 2015 |
A single amino acid substitution affects the substrate specificity of the seryl-tRNA synthetase homologue.
Topics: Alanine; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Bradyrhizobium; Catalytic Domain; Ligands; Magnesium; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Serine; Serine-tRNA Ligase; Substrate Specificity; Zinc | 2014 |
Biochemical characterization of pathogenic mutations in human mitochondrial methionyl-tRNA formyltransferase.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Escherichia coli Proteins; Humans; Hydroxymethyl and Formyl Transferases; Immunoblotting; Leigh Disease; Mitochondria; Mitochondrial Proteins; Molecular Sequence Data; Mutation; Protein Biosynthesis; RNA, Transfer, Met; Sequence Homology, Amino Acid; Serine | 2014 |
Mouse neutrophils express functional umami taste receptor T1R1/T1R3.
Topics: Alanine; Animals; Calcium; Cell Movement; Chemotaxis; Cytokines; Gene Expression Regulation; Lipopolysaccharides; Mice; Neutrophils; NF-kappa B; Phosphorylation; Receptors, G-Protein-Coupled; RNA; Sequence Analysis, RNA; Serine; Signal Transduction; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha | 2014 |
IKKβ is an IRF5 kinase that instigates inflammation.
Topics: Alanine; Animals; Cytokines; HEK293 Cells; Humans; I-kappa B Kinase; Inflammation; Interferon Regulatory Factors; Mass Spectrometry; Mice; Mutation; Phosphorylation; Protein Multimerization; Protein Structure, Tertiary; Serine | 2014 |
Serine 307 on insulin receptor substrate 1 is required for SOCS3 and TNF-α signaling in the rMC-1 cell line.
Topics: Alanine; Amino Acid Substitution; Animals; Caspase 3; Cell Line; Ependymoglial Cells; Feedback, Physiological; Gene Expression Regulation; Glucose; Insulin Receptor Substrate Proteins; Insulin Resistance; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Serine; Signal Transduction; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Tumor Necrosis Factor-alpha | 2014 |
L-Serine overproduction with minimization of by-product synthesis by engineered Corynebacterium glutamicum.
Topics: Alanine; Carbohydrate Metabolism; Corynebacterium glutamicum; Fermentation; Gene Deletion; Metabolic Engineering; Metabolic Flux Analysis; Recombination, Genetic; Serine; Valine; Zea mays | 2015 |
On the roles of the alanine and serine in the β-sheet structure of fibroin.
Topics: Alanine; Amino Acid Sequence; Dipeptides; Fibroins; Models, Molecular; Molecular Dynamics Simulation; Protein Structure, Secondary; Serine | 2015 |
Synthesis, resolution, and determination of absolute configuration of protected α-ethynylphenylalanine enantiomers.
Topics: Alanine; Benzyl Compounds; Circular Dichroism; Molecular Conformation; Serine; Stereoisomerism | 2015 |
Genome-wide association study of NMDA receptor coagonists in human cerebrospinal fluid and plasma.
Topics: Adolescent; Adult; Alanine; Chromatography, Liquid; Female; Genetic Variation; Genome-Wide Association Study; Glycine; Humans; Male; Membrane Transport Proteins; Middle Aged; Proline; Proline Oxidase; Quantitative Trait Loci; Receptors, N-Methyl-D-Aspartate; Serine; Tandem Mass Spectrometry; Young Adult | 2015 |
Phosphorylation of Atg31 is required for autophagy.
Topics: Alanine; Amino Acid Motifs; Aspartic Acid; Autophagy; Autophagy-Related Proteins; Carrier Proteins; Gene Expression Regulation, Fungal; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Nitrogen; Phagosomes; Phosphorylation; Protein Transport; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Sirolimus | 2015 |
Phosphorylation of Minichromosome Maintenance 3 (MCM3) by Checkpoint Kinase 1 (Chk1) Negatively Regulates DNA Replication and Checkpoint Activation.
Topics: Alanine; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Checkpoint Kinase 1; Chromatin; DNA Damage; DNA Replication; DNA, Single-Stranded; Gene Expression Regulation; HEK293 Cells; HeLa Cells; Humans; Mass Spectrometry; Minichromosome Maintenance Complex Component 3; Phosphorylation; Protein Kinases; Serine; Signal Transduction | 2015 |
L-Serine Deficiency Elicits Intracellular Accumulation of Cytotoxic Deoxysphingolipids and Lipid Body Formation.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Animals; Brain; Cells, Cultured; Female; Gene Knockout Techniques; Lipid Droplets; Lipids; Mice; Phosphoglycerate Dehydrogenase; Serine; Sphingolipids; Sphingosine | 2015 |
A novel alanine to serine substitution mutation in SoxS induces overexpression of efflux pumps and contributes to multidrug resistance in clinical Escherichia coli isolates.
Topics: Alanine; Amino Acid Substitution; Animals; Biological Transport, Active; Dogs; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Feces; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Mutation, Missense; Real-Time Polymerase Chain Reaction; Recombination, Genetic; Selection, Genetic; Serine; Trans-Activators | 2015 |
Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin.
Topics: Alanine; Amino Acid Substitution; Animals; Cell Line; Cytokines; Female; Gene Expression; Inflammation; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Mutation; Phosphoproteins; Phosphorylation; Primary Cell Culture; Recombinant Fusion Proteins; RNA Stability; RNA, Messenger; Salmonella Infections, Animal; Salmonella typhimurium; Serine; Tristetraprolin | 2015 |
In Vitro Study of L-Glutamate and L-Glutamine Transport in Retinal Pericytes: Involvement of Excitatory Amino Acid Transporter 1 and Alanine-Serine-Cysteine Transporter 2.
Topics: Alanine; Amino Acid Transport System ASC; Animals; Aspartic Acid; Cysteine; Excitatory Amino Acid Transporter 1; Glutamic Acid; Glutamine; Ion Transport; Male; Minor Histocompatibility Antigens; Pericytes; Rats, Wistar; Retina; Serine | 2015 |
Relationship between synovial fluid ARGS-aggrecan fragments, cytokines, MMPs, and TIMPs following acute ACL injury: A cross-sectional study.
Topics: Adolescent; Adult; Aggrecans; Alanine; Anterior Cruciate Ligament Injuries; Arginine; Body Mass Index; Cartilage, Articular; Cross-Sectional Studies; Cytokines; Epitopes; Female; Fibroblast Growth Factor 2; Gene Expression Regulation; Glycine; Humans; Inflammation; Knee Injuries; Male; Matrix Metalloproteinases; Prospective Studies; Serine; Synovial Fluid; Tissue Inhibitor of Metalloproteinase-3; Young Adult | 2015 |
A Novel Multivariate Index for Pancreatic Cancer Detection Based On the Plasma Free Amino Acid Profile.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Area Under Curve; Asparagine; Body Mass Index; Cross-Sectional Studies; Early Detection of Cancer; Fasting; Female; Histidine; Humans; Isoleucine; Japan; Male; Middle Aged; Pancreatic Neoplasms; Pancreatitis, Chronic; ROC Curve; Serine; Tryptophan; Young Adult | 2015 |
Simultaneous analysis of D-alanine, D-aspartic acid, and D-serine using chiral high-performance liquid chromatography-tandem mass spectrometry and its application to the rat plasma and tissues.
Topics: Alanine; Animals; Brain; Chromatography, High Pressure Liquid; D-Aspartic Acid; Male; Organ Specificity; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Serine; Stereoisomerism; Tandem Mass Spectrometry; Viscera | 2015 |
Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining.
Topics: Alanine; Ataxia Telangiectasia Mutated Proteins; BRCA1 Protein; Cell Cycle Proteins; Cell Death; Cell Line, Tumor; Cell Survival; Chromosome Aberrations; DNA Breaks, Double-Stranded; DNA Damage; DNA End-Joining Repair; DNA Repair; Glutamine; Homologous Recombination; Humans; Immunohistochemistry; Mitomycin; Mitosis; Mutation; Phosphorylation; Protein Structure, Tertiary; Recombinant Proteins; S Phase; Serine | 2015 |
Substrate Availability of Mutant SPT Alters Neuronal Branching and Growth Cone Dynamics in Dorsal Root Ganglia.
Topics: Alanine; Analysis of Variance; Animals; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Ganglia, Spinal; Growth Cones; Immunosuppressive Agents; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Neurons; Nonlinear Dynamics; Serine; Serine C-Palmitoyltransferase; Substrate Specificity; Transcription Factors | 2015 |
Identification of Critical Amino Acids Conferring Lethality in VopK, a Type III Effector Protein of Vibrio cholerae: Lessons from Yeast Model System.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Bacterial Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Alignment; Serine; Vibrio cholerae; Yeasts | 2015 |
Biomimetic Approach to Enhance Enzymatic Hydrolysis of the Synthetic Polyester Poly(1,4-butylene adipate): Fusing Binding Modules to Esterases.
Topics: Actinobacteria; Alanine; Alcaligenes faecalis; Amino Acid Substitution; Bacterial Proteins; Biomimetics; Butylene Glycols; Carboxylic Ester Hydrolases; Cloning, Molecular; Escherichia coli; Gene Expression; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Mutation; Polymers; Protein Engineering; Protein Structure, Tertiary; Recombinant Proteins; Serine; Structure-Activity Relationship | 2015 |
Compromising the phosphodependent regulation of the GABAAR β3 subunit reproduces the core phenotypes of autism spectrum disorders.
Topics: Alanine; Animals; Autism Spectrum Disorder; Behavior, Animal; Biotinylation; Cell Membrane; Dendritic Spines; Disease Models, Animal; Electroencephalography; Electrophysiological Phenomena; Epilepsy; Fear; gamma-Aminobutyric Acid; Gene Expression Regulation; Gene Knock-In Techniques; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mutation; Phenotype; Phosphorylation; Receptors, GABA-A; Serine; Social Behavior; Synapses | 2015 |
HSAN1 mutations in serine palmitoyltransferase reveal a close structure-function-phenotype relationship.
Topics: Adult; Aged; Alanine; Catalytic Domain; Child; Gas Chromatography-Mass Spectrometry; Gene Expression; HEK293 Cells; Hereditary Sensory and Autonomic Neuropathies; Humans; Isotope Labeling; Middle Aged; Models, Molecular; Mutation; Phenotype; Principal Component Analysis; Recombinant Proteins; Serine; Serine C-Palmitoyltransferase; Severity of Illness Index; Sphingolipids; Structural Homology, Protein; Structure-Activity Relationship; Young Adult | 2016 |
Improved Doxorubicin Encapsulation and Pharmacokinetics of Ferritin-Fusion Protein Nanocarriers Bearing Proline, Serine, and Alanine Elements.
Topics: Alanine; Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Screening Assays, Antitumor; Drug Stability; Ferritins; Half-Life; Humans; Mice, Inbred BALB C; Nanocapsules; Peptides; Polyethylene Glycols; Proline; Recombinant Fusion Proteins; Serine | 2016 |
Conformational Interconversions of Amino Acid Derivatives.
Topics: Alanine; Amino Acids; Cysteine; Models, Molecular; Molecular Conformation; Quantum Theory; Serine; Thermodynamics | 2016 |
Functional role of positively selected amino acid substitutions in mammalian rhodopsin evolution.
Topics: Adaptation, Physiological; Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Biological Evolution; Chlorocebus aethiops; COS Cells; G-Protein-Coupled Receptor Kinase 1; Gene Expression; Glutamine; Glycosylation; Humans; Mammals; Methionine; Models, Molecular; Mutation; Phenylalanine; Phosphorylation; Phylogeny; Protein Folding; Recombinant Proteins; Rhodopsin; Selection, Genetic; Serine | 2016 |
Unique albumin with two silent substitutions (540Thr→Ala and 546Ala→Ser): Insights into how albumin is recycled.
Topics: Alanine; Humans; Mutation; Serine; Serum Albumin; Spectrometry, Mass, Electrospray Ionization | 2016 |
Effects of straight alkyl chain, extra hydroxylated alkyl chain and branched chain amino acids on gastric emptying evaluated using a non-invasive breath test in conscious rats.
Topics: Acetic Acid; Administration, Oral; Alanine; Amino Acids; Amino Acids, Branched-Chain; Animals; Breath Tests; Consciousness; Gastric Emptying; Glycine; Isoleucine; Leucine; Male; Rats, Sprague-Dawley; Serine; Threonine; Valine | 2016 |
Human DNA polymerase ε is phosphorylated at serine-1940 after DNA damage and interacts with the iron-sulfur complex chaperones CIAO1 and MMS19.
Topics: Alanine; Amino Acid Substitution; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA; DNA Damage; DNA Polymerase II; DNA Repair; HEK293 Cells; Humans; Iron-Sulfur Proteins; Metallochaperones; Mutation; Osteoblasts; Phosphorylation; Poly-ADP-Ribose Binding Proteins; Protein Subunits; Serine; Transcription Factors | 2016 |
Nitrile-synthesizing enzyme: Screening, purification and characterization.
Topics: Alanine; Culture Media; Cyanides; Cysteine; Hydrogen-Ion Concentration; Kinetics; Lyases; Molecular Weight; Nitriles; Pseudomonas; Serine; Serine O-Acetyltransferase; Substrate Specificity; Temperature | 2016 |
Serine 421 regulates mutant huntingtin toxicity and clearance in mice.
Topics: Alanine; Animals; Aspartic Acid; Behavior, Animal; Chromosomes, Artificial, Bacterial; Disease Models, Animal; Disease Progression; Female; Gait; Genotype; Humans; Huntingtin Protein; Huntington Disease; Male; Maze Learning; Mice; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Nuclear Proteins; Phenotype; Phosphorylation; Proteasome Endopeptidase Complex; Serine | 2016 |
Correlation among chemical structure, surface properties and cytotoxicity of N-acyl alanine and serine surfactants.
Topics: Alanine; Amino Acids; Caco-2 Cells; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Design; Electron Spin Resonance Spectroscopy; Gases; Hemolysis; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; L-Lactate Dehydrogenase; Light; Magnetic Resonance Spectroscopy; Micelles; Scattering, Radiation; Serine; Sodium Dodecyl Sulfate; Solvents; Surface Properties; Surface-Active Agents; Temperature | 2016 |
GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis.
Topics: Acetylglucosamine; Alanine; Amino Acid Substitution; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Fibroblasts; Glucose; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Hexosamines; Human Umbilical Vein Endothelial Cells; Humans; Mice; Neovascularization, Physiologic; Phosphoproteins; Phosphorylation; Primary Cell Culture; Protein Processing, Post-Translational; Ribonucleotides; RNA, Small Interfering; Serine; Vascular Endothelial Growth Factor A | 2017 |
Novel synthetic analogues of avian β-defensin-12: the role of charge, hydrophobicity, and disulfide bridges in biological functions.
Topics: Alanine; Amino Acid Sequence; Animals; Anti-Infective Agents; Bacteria; Bacterial Load; beta-Defensins; Birds; Cell Line; Chemotaxis; Chickens; Colony Count, Microbial; Cysteine; Dendritic Cells; Disulfides; Drug Combinations; Hydrophobic and Hydrophilic Interactions; Macrophages; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Peptides; Protein Conformation; Serine; Sodium Chloride | 2017 |
Semi-microbiological synthesis of an active lysinoalanine-bridged analog of glucagon-like-peptide-1.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Glucagon-Like Peptide 1; Hydro-Lyases; Lactococcus lactis; Lysinoalanine; Membrane Proteins; Membrane Transport Proteins; Protein Processing, Post-Translational; SEC Translocation Channels; Serine; Substrate Specificity; Threonine | 2017 |
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Topics: Alanine; Alanine Racemase; Bacterial Proteins; Clostridioides difficile; Serine; Spores, Bacterial | 2017 |
Quantitative chiral analysis of amino acids in solution using enantiomer-selective photodissociation of cold gas-phase tryptophan via chiral recognition.
Topics: Alanine; Amino Acids; Serine; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Threonine; Tryptophan | 2017 |
Identification of YfiH (PgeF) as a factor contributing to the maintenance of bacterial peptidoglycan composition.
Topics: Alanine; Amino Acids; Bacterial Proteins; Cell Wall; Conserved Sequence; Escherichia coli; Escherichia coli Proteins; Glycine; Peptidoglycan; Serine | 2017 |
Dietary methionine source and level affect hepatic sulfur amino acid metabolism of broiler breeder hens.
Topics: Adenosine Deaminase; Alanine; Amino Acids, Sulfur; Animals; Butyrates; Chickens; Diet; Dietary Supplements; Female; Gene Expression; Glycine; Liver; Methionine; Methionine Adenosyltransferase; Serine; Tyrosine; Valine | 2017 |
Substrate-Induced Facilitated Dissociation of the Competitive Inhibitor from the Active Site of O-Acetyl Serine Sulfhydrylase Reveals a Competitive-Allostery Mechanism.
Topics: Acetyl Coenzyme A; Alanine; Allosteric Regulation; Bacterial Proteins; Binding Sites; Binding, Competitive; Catalytic Domain; Crystallography, X-Ray; Cysteine Synthase; Enzyme Inhibitors; Haemophilus influenzae; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Oligopeptides; Peptide Fragments; Protein Interaction Domains and Motifs; Recombinant Proteins; Salmonella enterica; Serine; Serine O-Acetyltransferase | 2017 |
Biogenesis of Hydrogen Sulfide and Thioethers by Cystathionine Beta-Synthase.
Topics: Alanine; Animals; Biomarkers; Catalysis; Cystathionine beta-Synthase; Cysteine; Haplorhini; Homocysteine; Hydrogen Sulfide; Kinetics; Mice; Mice, Knockout; Serine; Sulfides; Sulfur | 2018 |
DPP9 enzyme activity controls survival of mouse migratory tongue muscle progenitors and its absence leads to neonatal lethality due to suckling defect.
Topics: Alanine; Animals; Animals, Newborn; Animals, Suckling; Catalytic Domain; Cell Count; Cell Survival; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Mice; Mice, Transgenic; Muscle Development; Muscle Proteins; Muscle, Skeletal; Point Mutation; Receptors, CXCR4; Serine; Stem Cells; Tongue; Tongue Diseases | 2017 |
Prospects of PASylation® for the design of protein and peptide therapeutics with extended half-life and enhanced action.
Topics: Alanine; Animals; Drug Discovery; Half-Life; Humans; Models, Molecular; Peptides; Polyethylene Glycols; Proline; Serine | 2018 |
Chiral and Molecular Recognition through Protonation between Aromatic Amino Acids and Tripeptides Probed by Collision-Activated Dissociation in the Gas Phase.
Topics: Alanine; Amino Acids, Aromatic; Oligopeptides; Protons; Serine | 2018 |
Evolutionary instability of CUG-Leu in the genetic code of budding yeasts.
Topics: Alanine; Codon; Evolution, Molecular; Genetic Code; Genome, Fungal; Leucine; Nucleic Acid Conformation; Phylogeny; Protein Biosynthesis; RNA, Fungal; RNA, Transfer, Ala; RNA, Transfer, Leu; RNA, Transfer, Ser; Saccharomycetales; Selection, Genetic; Serine | 2018 |
ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase.
Topics: Alanine; Alanine-tRNA Ligase; Animals; Catalytic Domain; Cell Death; Female; Lysine; Male; Mice; Mice, Inbred C57BL; Mutation; Protein Binding; Protein Biosynthesis; Purkinje Cells; Serine | 2018 |
Quantification of thioether-linked glutathione modifications in human lens proteins.
Topics: Adolescent; Alanine; Aminobutyrates; Cataract; Cellular Senescence; Chromatography, Liquid; Crystallins; Cysteine; Glutathione; Humans; Lens, Crystalline; Middle Aged; Protein Processing, Post-Translational; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfides; Threonine; Tissue Donors; Young Adult | 2018 |
Disturbed sphingolipid metabolism with elevated 1-deoxysphingolipids in glycogen storage disease type I - A link to metabolic control.
Topics: Adolescent; Adult; Alanine; Female; Glucose; Glycogen Storage Disease Type I; Humans; Lipid Metabolism; Male; Serine; Serine C-Palmitoyltransferase; Sphingolipids; Young Adult | 2018 |
Comparative phenotypic analysis of CHO clones and culture media for lactate shift.
Topics: Alanine; Animals; Aspartic Acid; Cell Culture Techniques; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Culture Media; Glutamine; Lactic Acid; Metabolic Networks and Pathways; Phenotype; Serine | 2018 |
Tsc3 regulates SPT amino acid choice in
Topics: Alanine; Ceramides; Mass Spectrometry; Mutation; Plasmids; Saccharomyces cerevisiae; Serine; Serine C-Palmitoyltransferase; Sphingolipids; Substrate Specificity | 2018 |
Spider prey-wrapping silk is an α-helical coiled-coil/β-sheet hybrid nanofiber.
Topics: Alanine; Amino Acid Sequence; Animals; Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Fibroins; Nanofibers; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Serine; Silk; Spiders; Valine | 2018 |
A partial reconstitution implicates DltD in catalyzing lipoteichoic acid d-alanylation.
Topics: Alanine; Amino Acid Substitution; Bacterial Proteins; Carbon-Oxygen Ligases; Carrier Proteins; Enzyme Assays; Histidine; Kinetics; Lipopolysaccharides; Membrane Transport Proteins; Mutagenesis, Site-Directed; Mutation; Serine; Staphylococcus aureus; Teichoic Acids; Thiolester Hydrolases | 2018 |
Bioformation of Volatile and Nonvolatile Metabolites by
Topics: Acetates; Alanine; Carbon; Glutamic Acid; Glycine; Isoleucine; Mannitol; Mannose; Phenylacetates; Phenylalanine; Phenylethyl Alcohol; Proline; Saccharomycopsis; Serine; Sugar Alcohols; Threonine; Time Factors | 2018 |
A single serine to alanine substitution decreases bicarbonate affinity of phosphoenolpyruvate carboxylase in C4Flaveria trinervia.
Topics: Alanine; Amino Acid Substitution; Bicarbonates; Carbon Cycle; Flaveria; Kinetics; Mass Spectrometry; Phosphoenolpyruvate Carboxylase; Photosynthesis; Potassium Compounds; Serine | 2019 |
Restricting mitochondrial GRK2 post-ischemia confers cardioprotection by reducing myocyte death and maintaining glucose oxidation.
Topics: Alanine; Animals; Apoptosis; G-Protein-Coupled Receptor Kinase 2; Glucose; Heart Failure; Ischemia; Male; Mice; Mitochondria; Myocytes, Cardiac; Oxidation-Reduction; Oxygen Consumption; Phosphorylation; Point Mutation; Serine; Signal Transduction | 2018 |
Seminal plasma amino acid profile in different breeds of chicken: Role of seminal plasma on sperm cryoresistance.
Topics: Alanine; Amino Acids; Animals; Chickens; Cryopreservation; DNA Fragmentation; Glutamic Acid; Glycine; In Situ Nick-End Labeling; Male; Semen; Serine; Spermatozoa; Valine | 2019 |
Identification of a Novel Gene Encoding the Specialized Alanine Decarboxylase in Tea (
Topics: Alanine; Camellia sinensis; Carboxy-Lyases; Cloning, Molecular; Escherichia coli; Ethylamines; Gene Expression; Gene Expression Regulation, Plant; Genetic Vectors; Glutamates; Nitrogen; Organ Specificity; Phylogeny; Plant Leaves; Plant Proteins; Plant Roots; Recombinant Proteins; Seedlings; Serine; Tea | 2019 |
The novel HLA-C*08:80 allele identified by full-length sequencing of the HLA region.
Topics: Alanine; Alleles; Asian People; China; Exons; Genotype; High-Throughput Nucleotide Sequencing; Histocompatibility Testing; HLA-C Antigens; Humans; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; Serine | 2019 |
Enhancing bioactivity, physicochemical, and pharmacokinetic properties of a nano-sized, anti-VEGFR2 Adnectin, through PASylation technology.
Topics: Alanine; Animals; Escherichia coli; Female; Fibronectins; Human Umbilical Vein Endothelial Cells; Humans; Kinetics; Mice; Mice, Inbred BALB C; Peptide Fragments; Proline; Protein Domains; Protein Engineering; Serine; Surface Plasmon Resonance; Vascular Endothelial Growth Factor Receptor-2 | 2019 |
Efficacy of aldose reductase inhibitors is affected by oxidative stress induced under X-ray irradiation.
Topics: Alanine; Aldehyde Reductase; Catalysis; Cellular Microenvironment; Enzyme Activation; Enzyme Inhibitors; Humans; Oxidation-Reduction; Oxidative Stress; Serine; X-Rays | 2019 |
Phosphorylation of Forkhead Protein FoxO1 at S253 Regulates Glucose Homeostasis in Mice.
Topics: Alanine; Animals; Blood Glucose; Forkhead Box Protein O1; Glucagon; Glucose; Homeostasis; Insulin; Insulin Resistance; Islets of Langerhans; Liver; Mice, Inbred C57BL; Mice, Transgenic; Phosphorylation; Serine | 2019 |
D-glutamate, D-serine, and D-alanine differ in their roles in cognitive decline in patients with Alzheimer's disease or mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alanine; Alzheimer Disease; Behavioral Symptoms; Chromatography, Liquid; Cognition; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Diet; Female; Glutamic Acid; Hospitals, University; Humans; Male; Middle Aged; Neuropsychological Tests; Serine; Taiwan | 2019 |
HCV NS5A hyperphosphorylation is involved in viral translation modulation.
Topics: Alanine; Cell Line; Gene Expression Regulation, Viral; Hepacivirus; Humans; Mutation; Phosphorylation; Protein Multimerization; Serine; Viral Nonstructural Proteins; Virus Replication | 2019 |
Effects of Single Nucleotide Polymorphism Ala270Ser (rs316019) on the Function and Regulation of hOCT2.
Topics: Alanine; Amino Acid Substitution; Cell Membrane; Cell Proliferation; Cell Survival; Cisplatin; Creatinine; HEK293 Cells; Humans; Organic Cation Transporter 2; Polymorphism, Single Nucleotide; Serine | 2019 |
Glycosylation is a novel TGFβ1-independent post-translational modification of Smad2.
Topics: Alanine; Animals; Cell Count; Cell Nucleus; CHO Cells; Concanavalin A; Cricetinae; Cricetulus; Estradiol; Glycosylation; Humans; Lectins; MCF-7 Cells; Mutation; Plant Lectins; Protein Processing, Post-Translational; Protein Transport; Serine; Smad2 Protein; Transforming Growth Factor beta1 | 2020 |
The impact of different mutations at arginine141 on the structure, subunit exchange dynamics and chaperone activity of Hsp16.3.
Topics: Alanine; Amino Acid Substitution; Arginine; Bacterial Proteins; Binding Sites; Chaperonins; Glutamic Acid; Hydrophobic and Hydrophilic Interactions; Lactalbumin; Lysine; Mycobacterium tuberculosis; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Structure, Tertiary; Protein Subunits; Serine; Static Electricity; Structure-Activity Relationship; Substrate Specificity; Thermodynamics | 2020 |
DNA-PK: gatekeeper for IKKγ/NEMO nucleocytoplasmic shuttling in genotoxic stress-induced NF-kappaB activation.
Topics: Alanine; Animals; Cell Nucleus; Cytoplasm; DNA Damage; DNA-Activated Protein Kinase; DNA-Binding Proteins; HEK293 Cells; Humans; I-kappa B Kinase; Intracellular Signaling Peptides and Proteins; Mice; NF-kappa B; NIH 3T3 Cells; Phosphorylation; Serine; Signal Transduction | 2020 |
A Cuboid Spider Silk: Structure-Function Relationship and Polypeptide Signature.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Animals; Fibroins; Glycine; Materials Testing; Peptides; Protein Conformation, beta-Strand; Serine; Silk; Spiders; Structure-Activity Relationship | 2020 |
Alanine to serine substitutions drive thermal adaptation in a psychrophilic diatom cytochrome c
Topics: Adaptation, Physiological; Alanine; Amino Acid Sequence; Cytochromes c6; Diatoms; Electron Transport; Protein Unfolding; Scenedesmus; Sequence Alignment; Serine; Thermodynamics | 2020 |
New Proline, Alanine, Serine Repeat Sequence for Pharmacokinetic Enhancement of Anti-VEGF Single-Domain Antibody.
Topics: Alanine; Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Proliferation; Circular Dichroism; Half-Life; HEK293 Cells; Humans; Mice; Mice, Inbred BALB C; Proline; Protein Binding; Protein Structure, Secondary; Recombinant Fusion Proteins; Serine; Single-Domain Antibodies; Tissue Distribution; Vascular Endothelial Growth Factor A | 2020 |
1-Deoxydihydroceramide causes anoxic death by impairing chaperonin-mediated protein folding.
Topics: Alanine; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Cell Division; Chaperonins; Feeding Behavior; Hypoxia; Ion Channels; Mice; Mice, Inbred C57BL; Mutation; Myocardial Reperfusion Injury; Protein Folding; Saccharomyces cerevisiae; Serine; Sphingosine | 2019 |
Binding interaction of allethrin with esterase: Bioremediation potential and mechanism.
Topics: Alanine; Allethrins; Arginine; Biodegradation, Environmental; Esterases; Glutamates; Histidine; Leucine; Lysine; Methionine; Pseudomonas; Serine; Tyrosine | 2020 |
Serine restriction alters sphingolipid diversity to constrain tumour growth.
Topics: Alanine; Animals; Cell Adhesion; Cell Division; Diet; Female; Glycine; HCT116 Cells; Humans; Membrane Lipids; Mice; Mitochondria; Neoplasms; Phosphoglycerate Dehydrogenase; Pyruvic Acid; Serine; Serine C-Palmitoyltransferase; Spheroids, Cellular; Sphingolipids; Stress, Physiological; Xenograft Model Antitumor Assays | 2020 |
d-Serine and d-Alanine Regulate Adaptive Foraging Behavior in
Topics: Alanine; Animals; Brain; Caenorhabditis elegans; Caenorhabditis elegans Proteins; D-Amino-Acid Oxidase; Feeding Behavior; Movement; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Serine | 2020 |
Roles of N-methyl-D-aspartate receptors and D-amino acids in cancer cell viability.
Topics: Alanine; Amino Acids; Asparagine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Humans; Memantine; Middle Aged; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate; Serine; Skin Neoplasms | 2020 |
Prebiotic synthesis of cysteine peptides that catalyze peptide ligation in neutral water.
Topics: Alanine; Catalysis; Cysteine; Kinetics; Nitriles; Origin of Life; Peptides; Serine | 2020 |
Impact of immune checkpoint gene CD155 Ala67Thr and CD226 Gly307Ser polymorphisms on small cell lung cancer clinical outcome.
Topics: Aged; Alanine; Amino Acid Substitution; Antigens, Differentiation, T-Lymphocyte; Carcinoma, Small Cell; Female; Glycine; Humans; Lung Neoplasms; Male; Polymorphism, Genetic; Receptors, Virus; Serine; Threonine; Treatment Outcome | 2021 |
Biochemical characterization of specific Alanine Decarboxylase (AlaDC) and its ancestral enzyme Serine Decarboxylase (SDC) in tea plants (Camellia sinensis).
Topics: Alanine; Alanine Dehydrogenase; Camellia sinensis; Carboxy-Lyases; Escherichia coli; Glutamates; Plant Proteins; Recombinant Proteins; Serine; Tea | 2021 |
Role of a cysteine residue in substrate entry and catalysis in MtHIBADH: Analysis by chemical modifications and site-directed mutagenesis.
Topics: Alanine; Alcohol Oxidoreductases; Bacterial Proteins; Catalysis; Cysteine; Dinitrobenzenes; Hydrogen Bonding; Models, Molecular; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; NAD; p-Chloromercuribenzoic Acid; Protein Conformation; Recombinant Proteins; Serine; Structure-Activity Relationship; Substrate Specificity | 2021 |
Quantitative measurements of free and immobilized RgDAAO Michaelis-Menten constant using an electrochemical assay reveal the impact of covalent cross-linking on substrate specificity.
Topics: Alanine; Biosensing Techniques; Catalysis; D-Amino-Acid Oxidase; Electrochemical Techniques; Enzymes, Immobilized; Hydrogen Peroxide; Kinetics; Microelectrodes; Phenylenediamines; Proof of Concept Study; Reproducibility of Results; Serine; Substrate Specificity | 2021 |
PKR activity modulation by phosphomimetic mutations of serine residues located three aminoacids upstream of double-stranded RNA binding motifs.
Topics: Alanine; Amino Acid Substitution; Cardiovirus Infections; Double-Stranded RNA Binding Motif; eIF-2 Kinase; HeLa Cells; Host-Pathogen Interactions; Humans; Mutation; Phosphorylation; Protein Multimerization; RNA-Binding Proteins; Serine; Theilovirus | 2021 |
Identification of adducts formed between acrolein and alanine or serine in fried potato crisps and the cytotoxicity-lowering effect of acrolein in three cell lines.
Topics: Acrolein; Alanine; Apoptosis; Caco-2 Cells; Cell Survival; DNA Damage; Food-Processing Industry; Humans; Inactivation, Metabolic; Reactive Oxygen Species; Serine; Solanum tuberosum | 2021 |
Enhancing Electrochemical Biosensor Selectivity with Engineered d-Amino Acid Oxidase Enzymes for d-Serine and d-Alanine Quantification.
Topics: Alanine; Amino Acids; Biosensing Techniques; D-Amino-Acid Oxidase; Humans; Oxidoreductases; Saccharomyces cerevisiae; Serine | 2021 |
Plasma d-amino acids are associated with markers of immune activation and organ dysfunction in people with HIV.
Topics: Alanine; Amino Acids; Asparagine; Biomarkers; HIV Infections; Humans; Multiple Organ Failure; Proline; Serine | 2022 |
Comprehensively understanding metabolic pathways of protein during the anaerobic digestion of waste activated sludge.
Topics: Acetyl Coenzyme A; Alanine; Amino Acids; Anaerobiosis; Arginine; Glutamates; Glycine; Histidine; Leucine; Lysine; Metabolic Networks and Pathways; Methionine; Phenylalanine; Pyruvic Acid; Serine; Sewage; Threonine; Tyrosine | 2022 |
Targeting ASCT2-mediated glutamine metabolism inhibits proliferation and promotes apoptosis of pancreatic cancer cells.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Transport System ASC; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cysteine; Glutamine; Humans; Minor Histocompatibility Antigens; Pancreas; Pancreatic Neoplasms; Reactive Oxygen Species; Serine | 2022 |
Prevention of Arterial Elastocalcinosis: Differential Roles of the Conserved Glutamic Acid and Serine Residues of Matrix Gla Protein.
Topics: Alanine; Animals; Calcium-Binding Proteins; Extracellular Matrix Proteins; Glutamic Acid; Matrix Gla Protein; Mice; Serine; Vascular Calcification; X-Ray Microtomography | 2022 |
Blunted Amphetamine-induced Reinforcing Behaviors and Transporter Downregulation in Knock-in Mice Carrying Alanine Mutations at Threonine-258 and Serine-259 of Norepinephrine Transporter.
Topics: Alanine; Amphetamine; Animals; Down-Regulation; Male; Membrane Transport Proteins; Mice; Mutation; Norepinephrine Plasma Membrane Transport Proteins; Serine; Threonine | 2022 |
MX2 Viral Substrate Breadth and Inhibitory Activity Are Regulated by Protein Phosphorylation.
Topics: Alanine; Animals; Antiviral Agents; Aspartic Acid; Capsid Proteins; DNA, Viral; HIV Infections; HIV-1; Horses; Humans; Mice; Myxovirus Resistance Proteins; Phosphorylation; Serine; Virus Replication | 2022 |
Role of the gut-microbiota-metabolite axis in the rotenone model of early-stage Parkinson's Disease.
Topics: Alanine; Animals; Asparagine; Gastrointestinal Microbiome; Glutamine; Hydroxyproline; Methionine; Mice; Parkinson Disease; Rotenone; Serine; Threonine | 2022 |
Involvement of a Cluster of Basic Amino Acids in Phosphorylation-Dependent Functional Repression of the Ceramide Transport Protein CERT.
Topics: Alanine; Amino Acids, Basic; Biological Transport; Carrier Proteins; Ceramides; Golgi Apparatus; Humans; Phosphatidylinositols; Phosphorylation; Protein Serine-Threonine Kinases; Serine | 2022 |
Oral glucagon-like peptide 1 analogue ameliorates glucose intolerance in db/db mice.
Topics: Alanine; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Glucagon-Like Peptide 1; Glucose Intolerance; Hypoglycemic Agents; Mice; Mice, Inbred C57BL; Serine | 2022 |
CREB serine 133 is necessary for spatial cognitive flexibility and long-term potentiation.
Topics: Alanine; Animals; Cognition; Cyclic AMP Response Element-Binding Protein; Female; Hippocampus; Long-Term Potentiation; Male; Mammals; Mice; Phosphorylation; Serine | 2022 |
Mutation of histone H3 serine 28 to alanine influences H3K27me3-mediated gene silencing in Arabidopsis thaliana.
Topics: Alanine; Animals; Arabidopsis; Arabidopsis Proteins; Gene Expression Regulation, Plant; Gene Silencing; Histones; Mammals; Mutation; Polycomb Repressive Complex 2; Serine; Transcription Factors | 2022 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
Characterization of human cystathionine γ-lyase enzyme activities toward d-amino acids.
Topics: Alanine; Amino Acid Isomerases; Amino Acids; Animals; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Escherichia coli; Homoserine; Humans; Hydro-Lyases; Lyases; Mammals; Racemases and Epimerases; Serine | 2022 |
The combination of microbiome and metabolome to analyze the cross-cooperation mechanism of
Topics: Alanine; Animals; Echinacea; Fatty Acids, Volatile; Gastrointestinal Microbiome; Glycine; Glycosphingolipids; Humans; Leucine; Metabolome; Mice; Microbiota; Ornithine; Phenylalanine; Polysaccharides; Porphyrins; Serine; Threonine; Tryptophan; Tyrosine | 2022 |
Recent strains of influenza D virus create a new genetic cluster for European strains.
Topics: Alanine; Animals; Arginine; Asparagine; Aspartic Acid; Cattle; Cattle Diseases; Glycine; Nucleotides; Orthomyxoviridae; Orthomyxoviridae Infections; Phylogeny; Proline; Serine; Thogotovirus; Threonine; Valine | 2022 |
1-Deoxysphingolipid synthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells.
Topics: Agar; Alanine; Cell Membrane; Ceramides; Endocytosis; Metabolic Networks and Pathways; Neoplasms; Serine; Serine C-Palmitoyltransferase; Sphingolipids | 2022 |
NMR-Based Metabolomic Analysis of Cardiac Tissues Clarifies Molecular Mechanisms of CVB3-Induced Viral Myocarditis and Dilated Cardiomyopathy.
Topics: Alanine; Animals; Aspartic Acid; Biomarkers; Cardiomyopathy, Dilated; Coxsackievirus Infections; Enterovirus B, Human; Glutamic Acid; Glutamine; Glycine; Mice; Mice, Inbred BALB C; Myocarditis; Niacin; Niacinamide; Serine; Taurine; Threonine | 2022 |
Formation and reduction of furan in pumpkin puree by precursors, antioxidants, sterilization and reheating.
Topics: Alanine; alpha-Linolenic Acid; Antioxidants; Ascorbic Acid; beta Carotene; Butylated Hydroxytoluene; Chlorogenic Acid; Cucurbita; Fructose; Furans; Glucose; Glutamic Acid; Linoleic Acid; Quercetin; Serine; Sterilization; Water | 2023 |
[Determination of free amino acids in Eriocheir sinensis by ultra-high performance liquid chromatography-high resolution mass spectrometry].
Topics: Acetonitriles; Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brachyura; Chromatography, High Pressure Liquid; Cystine; Formates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Mass Spectrometry; Methionine; Perchlorates; Phenylalanine; Polypropylenes; Proline; Serine; Solvents; Threonine; Tyrosine; Valine; Water | 2022 |
LncRNA MSC-AS1, as an oncogene in melanoma, promotes the proliferation and glutaminolysis by regulating the miR-330-3p/ YAP1 axis.
Topics: Alanine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cysteine; Gene Expression Regulation, Neoplastic; Glutamates; Glutaminase; Glutamine; Humans; Ketoglutaric Acids; Melanoma; MicroRNAs; Oncogenes; RNA, Long Noncoding; Serine; YAP-Signaling Proteins | 2022 |
Effects of hydrogen peroxide and l-tryptophan on antioxidative potential, apoptosis, and mammalian target of rapamycin signaling in bovine intestinal epithelial cells.
Topics: Alanine; Animals; Antioxidants; Apoptosis; Catalase; Cattle; Cysteine; Epithelial Cells; Hydrogen Peroxide; Large Neutral Amino Acid-Transporter 1; Mammals; Oxidative Stress; Serine; Signal Transduction; Superoxide Dismutase; TOR Serine-Threonine Kinases; Tryptophan | 2022 |
Rapid differentiation of hiPSCs into functional oligodendrocytes using an OLIG2 synthetic modified messenger RNA.
Topics: Alanine; Humans; Induced Pluripotent Stem Cells; Neurodegenerative Diseases; Oligodendrocyte Transcription Factor 2; Oligodendroglia; RNA, Messenger; Serine; Transcription Factors | 2022 |
Efficient secretory production of proline/alanine/serine (PAS) biopolymers in Corynebacterium glutamicum yielding a monodisperse biological alternative to polyethylene glycol (PEG).
Topics: Alanine; Amino Acids; Biopolymers; Corynebacterium glutamicum; Peptides; Polyethylene Glycols; Proline; Serine | 2022 |
Benincasa hispida extracts positively regulated high salt-induced hypertension in Dahl salt-sensitive rats: Impact on biochemical profile and metabolic patterns.
Topics: Alanine; Amino Acids; Animals; Antihypertensive Agents; Antioxidants; Aspartic Acid; Cucurbitaceae; Glycine; Hypertension; Phenylalanine; Plant Extracts; Rats; Rats, Inbred Dahl; Renal Insufficiency; Serine; Sodium Chloride; Sodium Chloride, Dietary; Threonine; Tyrosine | 2022 |
Procyanidin B2 3,3″-di-O-gallate suppresses IFN-γ production in murine CD4
Topics: Alanine; Amino Acid Transport System ASC; Amino Acids; Animals; CD4-Positive T-Lymphocytes; Cysteine; Glutamine; Interferon-gamma; Mammals; Mice; Minor Histocompatibility Antigens; Proanthocyanidins; Serine; T-Lymphocytes; TOR Serine-Threonine Kinases | 2023 |
Metabolic pathway analysis of hyperuricaemia patients with hyperlipidaemia based on high-throughput mass spectrometry: a case‒control study.
Topics: Alanine; Aspartic Acid; Biomarkers; Case-Control Studies; Glycine; Humans; Hyperlipidemias; Hyperuricemia; Linoleic Acid; Mass Spectrometry; Metabolic Diseases; Metabolic Networks and Pathways; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine | 2022 |
Effect of alanine versus serine at position 88 of human transthyretin mutants on the protein stability.
Topics: Alanine; Humans; Molecular Dynamics Simulation; Prealbumin; Protein Stability; Serine; Thermodynamics | 2023 |
Determination of D-serine and D-alanine Tissue Levels in the Prefrontal Cortex and Hippocampus of Rats After a Single Dose of Sodium Benzoate, a D-Amino Acid Oxidase Inhibitor, with Potential Antipsychotic and Antidepressant Properties.
Topics: Alanine; Animals; Antidepressive Agents; Antipsychotic Agents; D-Amino-Acid Oxidase; Hippocampus; Oxidoreductases; Prefrontal Cortex; Rats; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Sodium Benzoate | 2023 |
Metabolomics profiling of seminal plasma in obesity-induced asthenozoospermia.
Topics: Aconitic Acid; Alanine; Asthenozoospermia; Citrulline; Glucose; Glutamic Acid; Glycine; Humans; Leucine; Lysine; Male; Metabolomics; Phenylalanine; Proline; Semen; Serine; Succinic Acid; Threonine; Tyrosine; Valine | 2023 |
Divergent amino acid and sphingolipid metabolism in patients with inherited neuro-retinal disease.
Topics: Alanine; Amino Acids; Animals; Glycine; Hereditary Sensory and Autonomic Neuropathies; Mice; Retinal Diseases; Serine; Sphingolipids; Sphingomyelins | 2023 |
lncRNA SYTL5-OT4 promotes vessel co-option by inhibiting the autophagic degradation of ASCT2.
Topics: Alanine; Carrier Proteins; Cell Line, Tumor; Cysteine; Humans; In Situ Hybridization, Fluorescence; Liver Neoplasms; Membrane Proteins; Membrane Transport Proteins; RNA, Long Noncoding; Serine | 2023 |
Improving the isolated microspore culture in eggplant (Solanum melongena L.) with amino acid nutrition.
Topics: Alanine; Amino Acids; Glutamine; Proline; Serine; Solanum melongena | 2023 |
Discrimination of blood metabolomics profiles in neonates with idiopathic polyhydramnios.
Topics: Alanine; Asparagine; Aspartic Acid; Cesarean Section; Child; Chromatography, Liquid; Female; Glutamates; Homocysteine; Humans; Infant, Newborn; Phenylalanine; Polyhydramnios; Pregnancy; RNA, Transfer; Serine; Tandem Mass Spectrometry | 2023 |
Transcriptomics integrated with metabolomics reveals perfluorobutane sulfonate (PFBS) exposure effect during pregnancy and lactation on lipid metabolism in rat offspring.
Topics: Alanine; Animals; Aspartic Acid; Cytochrome P-450 Enzyme System; Female; Gene Expression Profiling; Glycine; Lactation; Lipid Metabolism; Metabolomics; Pantetheine; Phosphates; Pregnancy; Rats; Serine; Threonine; Transcriptome; Xenobiotics | 2023 |
Enantiodetermining processes in the synthesis of alanine, serine, and isovaline.
Topics: Alanine; Amino Acids; Serine; Stereoisomerism; Valine | 2023 |
Detection and identification of amino acids and proteins using their intrinsic fluorescence in the visible light spectrum.
Topics: Alanine; Amino Acids; Arginine; Cystine; Fluorescence; Glycine; Leucine; Methionine; Proteins; Serine; Threonine; Tyrosine; Valine | 2023 |
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Prediction of the GTPase activities by using the semiempirical molecular orbital theory.
Topics: Amino Acid Substitution; Chemistry, Physical; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Hydrolysis; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Proto-Oncogene Proteins p21(ras); Thermodynamics | 1998 |
A green fluorescent chemosensor for amino acids provides a versatile high-throughput screening (HTS) assay for proteases.
Topics: Amino Acids; Copper; Drug Evaluation, Preclinical; Endopeptidases; Fluoresceins; Fluorescence; Kinetics; Ligands; Molecular Probes | 2003 |