alanine has been researched along with pyruvic acid in 314 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 93 (29.62) | 18.7374 |
| 1990's | 70 (22.29) | 18.2507 |
| 2000's | 66 (21.02) | 29.6817 |
| 2010's | 71 (22.61) | 24.3611 |
| 2020's | 14 (4.46) | 2.80 |
| Authors | Studies |
|---|---|
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Camus, F; Chaussain, M; Defoligny, C; Eymard, B; Fardeau, M | 1 |
| Berry, MN; Gregory, RB; Phillips, JW | 1 |
| Borth, N; Katinger, H; Reiter, M; Steindl, F; Weigang, F | 1 |
| Cosseddu, D; Linari, F; Marangella, M; Pellegrino, S; Petrarulo, M | 1 |
| Bhatia, MB; Futaki, S; Manning, JM; Martinez del Pozo, A; Ringe, D; Soda, K; Yoshimura, T | 1 |
| Dua, RK; Phillips, RS | 1 |
| Alemany, M; Argilés, MJ; Casado, J; Fernández-López, JA | 1 |
| Bol'shakova, TN; Erlagaeva, RS; Gershanovich, VN; Grigorenko, IuA; Molchanova, ML | 1 |
| Altekar, W; Rajagopalan, R | 1 |
| Nattrass, M; Robertson, DA; Singh, BM | 1 |
| Hild, R; Rexroth, W | 1 |
| Herndon, DN; Jahoor, F; Miyoshi, H; Wolfe, RR | 1 |
| Fujimoto, S; Kaneko, M; Kikugawa, M; Tamaki, N | 1 |
| Bohnensack, R; Fritz, S | 1 |
| Ardawi, MS; Kateilah, SM; Majzoub, MF; Newsholme, EA | 1 |
| Benzi, L; Brunetti, P; Cecchetti, P; Di Carlo, A; Di Cianni, G; Giannarelli, R; Gregorio, F; Marchetti, P; Navalesi, R; Villani, G | 1 |
| Fischer, Y; Kammermeier, H; Rose, H | 1 |
| Kenney, R; Parrish, A; Tomacelli, C; Zikira, M | 1 |
| Dumdey, R; Holzhütter, HG; Müller, M; Rathmann, J | 1 |
| Oliver, J; Salto, R; Sola, MM; Vargas, AM | 1 |
| Hale, PJ; Nattrass, M | 1 |
| Baverel, G; Martin, G; Michoudet, C | 1 |
| Barlow, J; Devlin, JT; Horton, ES | 1 |
| Aynsley-Green, A; Boyes, S; Schwartz, RM | 1 |
| Ardawi, MS; Ashy, AA; Jamal, YS; Khoja, SM | 1 |
| Aoki, T; Benn, JJ; Bozzard, SJ; Gerich, J; Kelley, D; Mitrakou, A; Sonksen, PH; Sorensen, J | 1 |
| Fischer, B; Holm, E; Jacob, S | 1 |
| Isgro, F; Koeth, T; Manzl, G; Rexroth, W; Weicker, H | 1 |
| Buc, HA; Claeyssens, S; Lavoinne, A; Matray, F; Pinosa, M | 1 |
| Mercer, JR; Silva, SV | 1 |
| Laycock, M; McInnes, AG; Shapiro, S; Vining, LC; Walter, JA | 1 |
| Allignet, E; Junco, E; Lemieux, C; Lemieux, G; Perez, R | 1 |
| Evered, DF; Masola, B; Peters, TJ | 1 |
| Ishihara, M; Iwasaki, K; Mano, K; Matsuzawa, T; Yugari, Y | 1 |
| Lenartowicz, E; Wojtczak, AB | 1 |
| Grunewald, RW; Jans, AW; Kinne, RK | 1 |
| Thompson, JR; Wu, GY | 1 |
| Reinacher, M; Schering, B; Schoner, W | 1 |
| Hodson, AW; Skillen, AW; Stappenbeck, R | 1 |
| Cook, RA; Lang, VJ; Leystra-Lantz, C | 1 |
| Bessman, SP; Mohan, C | 2 |
| Blum, JJ; Darling, TN | 1 |
| Graba, JP; Liebs, P; Riedel, K; Schrapel, D; Tischler, U | 1 |
| Adams, CE; Mortimore, GE; Wert, JJ | 1 |
| Noakes, TD; Peters Futre, EM; Raine, RI; Terblanche, SE | 1 |
| Dijkema, C; Visser, J | 1 |
| Brockman, RP | 1 |
| Agius, L | 1 |
| Brown, BI; Burke, BA; Tuchman, M; Ulstrom, RA | 1 |
| Dröge, W; Eck, HP; Kriegbaum, H; Mihm, S | 1 |
| Dröge, W; Mihm, S | 1 |
| Albisser, AM; McPhedran, NT; Nomura, M | 1 |
| Black, E; Hale, PJ; Nattrass, M | 1 |
| Albisser, AM; Bahoric, A; Greenberg, GR; Nomura, M | 1 |
| Ayuso, MS; Parrilla, R; Pérez-Sala, D | 1 |
| Ahlborg, G; Björkman, O | 1 |
| Miyamae, Y; Ohta, T; Sugano, T; Tarui, A | 1 |
| Ayuso, MS; Martin-Requero, A; Parrilla, R | 1 |
| Alberti, KG; Elliott, MJ; Holden, MP; McKnight, CK; Pearson, DT | 1 |
| Olson, MS; Patel, TB | 1 |
| Marchok, AC; Wasilenko, WJ | 1 |
| Herrera, E; Lasunción, MA; Zorzano, A | 1 |
| Snijders, PM; Valkenburg, PW; van der Meer, C | 1 |
| Doesburg, WH; Gabreëls, FJ; Lamers, KJ; Lemmens, WA; Renier, WO; Romsom, AC; Wevers, RA | 1 |
| Hassinen, IE; Hiltunen, JK; Nuutinen, EM; Peuhkurinen, KJ; Pietiläinen, EP | 1 |
| Baverel, G; Martin, G | 1 |
| Alberti, KG; Blesa-Malpica, G; Burrin, J; Hammond, VA; Johnston, DG; Orskov, H; Pernet, A | 1 |
| Alberti, KG; Gill, GV; Johnston, DG; Orskov, H; Pernet, A; Walker, M | 1 |
| Caldecourt, MA; Palmer, TN; Sugden, MC; Warner, JP | 1 |
| Alberti, KG; Barnett, AH; Eff, C; Leslie, RD; Pyke, DA; Spiliopoulos, AJ; Stubbs, WA | 1 |
| Boyd, J; Brindle, KM; Campbell, ID; Porteous, R; Soffe, N | 1 |
| Avogaro, A; Del Prato, S; Duner, E; Ferrara, D; Marescotti, C; Nosadini, R; Tiengo, A | 1 |
| Antonella, MA; Brunetti, P; Bueti, A; Calabrese, G; Fabietti, PG; Massi Benedetti, M; Santeusanio, F | 1 |
| Alberti, KG; Capaldo, B; Cook, DB; Heaton, A; Home, PD; Massi-Benedetti, M; Worth, R | 1 |
| Hassinen, IE; Hiltunen, JK; Peuhkurinen, KJ | 1 |
| Kumaoka, H; Yamada, K | 1 |
| Hampson, RK; Olson, MS; Taylor, MK | 1 |
| Nakatani, T; Ozawa, K; Tobe, T; Yasuda, K | 1 |
| Mortimore, GE; Pösö, AR | 1 |
| Fiolitakis, E; Kula, MR; Wandrey, C; Wichmann, U | 1 |
| Barrio, JR; Ropchan, JR | 1 |
| Björkman, O; Eriksson, LS | 1 |
| Connor, H; Ledingham, JG; Woods, HF | 1 |
| Geelen, MJ | 1 |
| Allan, EH; Martin, AD; Titheradge, MA | 1 |
| Barron, LL; Olson, MS; Patel, TB | 1 |
| Alberti, KG; Home, PD; Johnston, DG; Nattrass, M; Nosadini, R; Noy, GA; Orskov, H | 1 |
| Alberti, KG; Burrin, J; Nattrass, M; Sheppard, MC | 1 |
| Arizmendi, C; Benito, M; Maties, M; Medina, JM | 1 |
| Brandt, NJ; Christensen, E; Hansen, TL | 1 |
| Kalkhoff, RK; Rushakoff, RJ | 1 |
| Demigné, C; Rémésy, C | 1 |
| Groen, AK; Sips, HJ; Tager, JM; Vervoorn, RC | 1 |
| Hassinen, IE; Peuhkurinen, KJ | 1 |
| Maughan, RJ | 1 |
| Peuhkurinen, KJ | 1 |
| Bartels, PD; Folke, M; Sestoft, L | 1 |
| Jorfeldt, L; Stjernström, H; Wiklund, L | 1 |
| Baverel, G; Forissier, M | 1 |
| Forgo, P; Kover, KE; Podanyi, B; Sumegi, B | 1 |
| Sakagishi, Y | 1 |
| Bindoff, LA; Jackson, MJ; Johnson, MA; Morris, AA; Schaefer, JA; Turnbull, DM | 1 |
| Corkey, BE; Curtiss, D; Kilpatrick, L; Nachiappan, V | 1 |
| Clemens, MG; Paidas, CN | 1 |
| Oliver, FJ; Salto, R; Sola, MM; Vargas, AM | 1 |
| Arthur, M; Courvalin, P; Depardieu, F; Dutka-Malen, S; Reynolds, PE | 1 |
| Canioni, P; Merle, M; Portais, JC; Schuster, R | 1 |
| Katz, J; Lee, WN; Wals, P | 1 |
| Camplo, M; Charvet, AS; Faury, P; Kraus, JL | 1 |
| Biesemans, M; Malaisse, WJ; Willem, R | 1 |
| Blair, JB; Cline, GW; Petersen, KF; Shulman, GI | 1 |
| Brandi, LS; Fossati, N; Giunta, F; Mazzanti, T; Oleggini, M | 1 |
| Bhaumik, SR; Sonawat, HM | 1 |
| Argilés, JM; Domènech, M; López-Soriano, FJ | 1 |
| Shirley, B | 1 |
| Díaz, R; Gamazo, C; López-Goñi, I; Moriyón, I; Vitas, AI | 1 |
| Brown, J; Gore, DC; Lee, R | 1 |
| Hotta, N; Kobayashi, M; Koh, N; Komori, T; Sakakibara, F; Sakamoto, N | 1 |
| Pishko, EJ; Robertus, JD | 1 |
| Huang, X; McKenna, MC; Sonnewald, U; Stevenson, J; Zielke, HR | 1 |
| Campillo, JE; Gómez-Zubeldia, MA; Moreno, JC; Muñoz-Casillas, M; Ropero, F; Tormo, MA | 1 |
| Anderson, R; Orlygsson, J; Svensson, BH | 1 |
| Aki, K; Kokubo, T; Massey, V; Misaki, H; Ohkuma-Soyejima, T; Yorita, K | 1 |
| Bachelard, HS; Jones, P; Schousboe, A; Sonnewald, U; Taylor, A; Westergaard, N | 1 |
| Fang, CH; Fischer, JE; Hasselgren, PO; James, JH; Paul, RJ; Schrantz, SJ | 1 |
| Fernández-González, C; Gil, JA; Kalinowski, J; Martín, JF; Mateos, LM; Pühler, A; Schäfer, A; Schwarzer, A | 1 |
| Dickson, AJ; Murray, K | 1 |
| Bazotte, RB; Brunaldi, K; Ferraz, M; Oliveira, CE | 1 |
| Sparks, S | 1 |
| Imperiali, B; Roy, RS | 1 |
| Ishihara, T; Kondo, S; Naka, T; Shimizu, E; Yorifuji, T | 1 |
| Chait, BT; Erickson, SD; Haller, I; Manning, JM; Martinez del Pozo, A; Petsko, G; Ringe, D; Soda, K; van Ophem, PW; Yoshimura, T | 1 |
| Beylot, M; Brunengraber, H; Diraison, F; Large, V | 1 |
| Blackburn, BJ; Corbin, I; Novak, M; Simcoff, R | 1 |
| Baker, PJ; Rice, DW; Sawa, Y; Sedelnikova, SE; Shibata, H | 1 |
| Di Pietro, MC; Guerranti, R; Leoncini, R; Marinello, E; Pagani, R; Rosi, F; Vannoni, D | 1 |
| Dixon, RM; Griffin, JL; Matthews, PM; Radda, GK; Rae, C | 1 |
| Bracht, A; Ishii-Iwamoto, EL; Kemmelmeier, FS; Nascimento, EA; Tonon, FA | 1 |
| Kim, BG; Shin, JS | 2 |
| Bashan, N; Gutman, A; Khamaisi, M; Potashnik, R; Rudich, A; Tritschler, HJ | 1 |
| Allen, DL; DeRose, EF; Gabel, SA; London, RE | 1 |
| Caldwell, DR; McHolland, LE | 1 |
| Eriksson, BO; Lundell, KH; Sabel, KG | 1 |
| Backlund, P; Cooper, GW; de la Haba, G; Flaks, JG; Khatami, M | 1 |
| Amado, CB; Bracht, A; Fedatto Júnior, Z; Ishii-Iwamoto, EL; Kelmer-Bracht, AM; Panerari, AD; Vicentini, GE | 1 |
| Burelle, Y; Fillipi, C; Leverve, X; Péronnet, F | 1 |
| Harano, M; Kawada, N; Ryozo, N; Takakura, N; Tanaka, N; Tsuge, H | 1 |
| Cook, PF; Karsten, WE; Liu, D | 1 |
| Esaki, N; Hirotsu, K; Jhee, KH; Kawata, Y; Miles, EW; Miyahara, I; Soda, K; Takeda, S; Yoshimura, T | 1 |
| Efendic, S; Fisher, SJ; Giacca, A; Lickley, HL; Shi, ZQ; Vranic, M | 1 |
| Chen, X; Dieckmann, T; Jin, X; Medhekar, R; Toney, MD; Zhou, X | 1 |
| Thompson, SN | 1 |
| Decking, UK; Deussen, A; Preckel, B; Schrader, J; Skwirba, S; Thämer, V; Zimmermann, MF | 1 |
| Leibfritz, D; Richter-Landsberg, C; Zwingmann, C | 1 |
| Gabel, SA; London, RE | 1 |
| Bazotte, RB; Borba-Murad, GR; Ceddia, RB; Curi, R; de Souza, HM; Vardanega-Peicher, M | 1 |
| Chew, SF; Ip, YK; Lem, CB; Randall, DJ; Wilson, JM | 1 |
| Jordan, F; Sergienko, EA | 1 |
| Dunn, MF; Ferrari, D; Miles, EW; Yang, LH | 1 |
| Bélanger, P; Burelle, Y; Désy, F; Gascon-Barré, M; Lavoie, JM | 1 |
| Chang, S; Morowitz, H; Peterson, E | 1 |
| Bishop, JC; Cross, SD; Waddell, TG | 1 |
| Hunt, NH; Maitland, A; Rae, C; Sanni, LA; Stocker, R | 1 |
| Hamarat Baysal, S; Uslan, AH | 1 |
| Battaglia, FC; Meschia, G; Narkewicz, MR; Teng, C; Wilkening, RB | 1 |
| Fujitani, S; Ishizaki-Koizumi, S; Nishiguchi, S; Sonaka, I | 1 |
| Bazotte, RB; Curi, R; Galletto, R; Gazola, S; Gazola, VA; Limeira, DM; Lopes, G | 1 |
| Ammatuna, M; Battezzati, A; Caumo, A; Coppa, J; Fattorini, A; Luzi, L; Mazzaferro, V; Regalia, E; Romito, R; Sereni, LP | 1 |
| Brennan, L; Brindle, KM; Flatt, PR; Hewage, C; Malthouse, JP; McClenaghan, N; Newsholme, P; Shine, A | 1 |
| Chadha, PL; Crandall, SC; Qureshi, T; Sumida, KD | 1 |
| Bryła, J; Derlacz, RA; Jagielski, AK; Jarzyna, R; Lietz, T; Winiarska, K; Wohner, D | 1 |
| Glushka, JN; Whitman, WB; Yang, YL | 1 |
| Fois, E; Gamba, A; Tilocca, A; Vanoni, MA | 1 |
| Bélanger, P; Couturier, K; Désy, F; Gauthier, MS; Lavoie, JM | 1 |
| Dawson, KD; Gibala, MJ; Howarth, KR; Tarnopolsky, MA; Wong, ND | 1 |
| Hamada-Sato, N; Imada, C; Inaba, Y; Kobayashi, T; Watanabe, E | 1 |
| Brocks, C; Chatham, JC; Lloyd, S | 1 |
| Fuller, BJ; So, PW | 1 |
| Heigenhauser, GJ; Richards, JG; Wood, CM | 1 |
| Fujino, MA; Nagata, K; Nagata, Y; Nakajima, K; Sato, T; Tamura, T | 1 |
| Fischetti, VA; Lee, SG | 1 |
| JORDAN, DC | 1 |
| JONES, F; MUIRHEAD, EE; STIRMAN, JA | 1 |
| ISHIHARA, H; YONEDA, M | 1 |
| BEREZOVSKAIA, NN; KAPLANSKII, SIa | 1 |
| BOCCHINI, V; SALVATORE, F | 1 |
| BRICTEUX, S; DEWANDRE, A; FLORKIN, M; FUKUDA, T | 1 |
| BANERJEE, R; WURMSER, R | 1 |
| GUMBMANN, M; TAPPEL, AL | 1 |
| KRAHL, ME; WOLL, IG | 1 |
| NATSUME, K; YAGI, K | 1 |
| BALAZS, R | 1 |
| GAITONDE, MK | 1 |
| MACLEOD, P; MORGAN, ME | 1 |
| Castro-Chaves, P; Guerra, MS; Leite-Moreira, AF; Lima-Carneiro, A; Roncon-Albuquerque, R | 1 |
| Bui, BV; Kalloniatis, M; Vingrys, AJ | 1 |
| Aitken, SM; Kirsch, JF | 1 |
| Bergman, BC; Brooks, GA; Henderson, GC; Horning, MA; Lehman, SL; Wolfel, EE | 1 |
| Gawandi, VB; Lima, S; Liskey, D; Phillips, RS | 1 |
| Leese, HJ; Orsi, NM | 1 |
| Altman, E; Eiteman, MA; Lee, M; Smith, GM | 1 |
| Jahoor, F; Shangraw, RE | 1 |
| Chaudhary, LC; McKain, N; Miyagawa, E; Walker, ND; Wallace, RJ | 1 |
| Acco, A; Bracht, A; Comar, JF | 1 |
| Cummings, C; Filipek, PA; Gargus, JJ; Juranek, J; Nguyen, MT | 1 |
| Bryla, J; Chodnicka, K; Doroszewska, R; Drozak, J; Winiarska, K | 1 |
| Seah, SY; Wang, W | 2 |
| Eggeling, L; Kennerknecht, N; Marienhagen, J; Sahm, H | 1 |
| Glover, GH; Hurd, RE; Levin, YS; Mayer, D; Spielman, DM | 1 |
| Bracht, A; Broetto-Biazon, AC; de Sá-Nakanishi, AB; Ishii-Iwamoto, EL; Kelmer-Bracht, AM | 1 |
| Kaksonen, AH; Kroppenstedt, RM; Puhakka, JA; Schumann, P; Spring, S | 1 |
| Ardenkjaer-Larsen, JH; Golman, K; Lerche, M; Pehrson, R; Zandt, RI | 1 |
| Bartek, T; Blombach, B; Eikmanns, BJ; Holátko, J; Oldiges, M; Schreiner, ME | 1 |
| Bornik, MA; Murkovic, M | 1 |
| Hurd, RE; Levin, YS; Mayer, D; Spielman, DM; Yen, YF | 1 |
| Bracht, A; Comar, JF; Nascimento, EA; Suzuki-Kemmelmeier, F | 1 |
| Le Bars, D; Yvon, M | 1 |
| Brittain, JH; Grist, TM; Reeder, SB; Yen, YF | 1 |
| Bok, R; Chen, AP; Hurd, RE; Joun, D; Kurhanewicz, J; Nelson, SJ; Vigneron, DB; Xu, D; Zhang, V | 1 |
| Bracht, A; Ishii-Iwamoto, EL; Maioli, MA; Mingatto, FE | 1 |
| Eggeling, L; Marienhagen, J | 1 |
| Bazotte, RB; Curi, R; Felisberto-Junior, AM; Garcia, RF; Oliveira-Yamashita, F | 1 |
| Al-Helal, M; Biagini, GA; Bray, PG; Fisher, N; Lian, LY; Roslaini, AM; Ward, SA | 1 |
| Guo, C; Sheppard, D; Tugarinov, V | 1 |
| Caughey, AB; Cohn, BR; Iman, R; Joe, BN; Kornak, J; Kurhanewicz, J; Swanson, MG; Vahidi, K; Yu, J; Zhang, VY; Zhao, S | 1 |
| Albers, MJ; Bok, R; Chen, AP; Hurd, RE; Kurhanewicz, J; Nelson, SJ; Park, I; Tropp, J; Vigneron, DB; Yen, YF; Zhang, V; Zierhut, ML | 1 |
| Araújo, WL; Fernie, AR; Licausi, F; Nunes-Nesi, A; Rocha, M; Sodek, L; van Dongen, JT | 1 |
| Butts Pauly, K; Hurd, R; King, R; Le Roux, P; Mayer, D; Pfefferbaum, A; Spielman, D; Tropp, J; Vasanawala, S; Yen, YF | 1 |
| Ito, S; Kamo, M; Kato, H; Kezuka, Y; Kunimatsu, K; Tamura, H; Yoshida, Y | 1 |
| Meshitsuka, S; Morio, Y; Nagashima, H; Nanjo, Y; Teshima, R; Yamane, K | 1 |
| Bennette, N; Bryant, DA; Dismukes, GC; McNeely, K; Xu, Y | 1 |
| Bala Amutha, K; Murugesan, AG | 1 |
| Flores, E; Herrero, A; Pernil, R | 1 |
| Kim, SH; Reitzer, L; Schneider, BL | 1 |
| Cerdan, S; Contreras, L; Garzón, M; Kobayashi, K; Llorente-Folch, I; Pardo, B; Rodrigues, TB; Saheki, T; Satrústegui, J | 1 |
| Hurd, R; Josan, S; Mayer, D; Pfefferbaum, A; Spielman, D; Yen, YF | 1 |
| Kakimoto, N; Katayama, K; Koga, Y; Matsuishi, T; Naito, E; Povalko, N; Tanaka, M | 1 |
| Bok, R; Hu, S; Larson, PE; Reed, G; Shin, P; Vigneron, DB; von Morze, C | 1 |
| Alves, MG; Carvalho, RA; Cavaco, JE; Oliveira, PF; Rato, L; Socorro, S | 1 |
| Chua, MS; Clarke-Katzenberg, RH; Darpolor, MM; Glazer, GM; Hofmann, LV; Hurd, RE; Josan, S; Mayer, D; Pfefferbaum, A; Senadheera, L; Shi, W; So, S; Spielman, DM; Xing, L; Yen, YF | 1 |
| Anderton, B; Balakrishnan, A; Bok, RA; Goga, A; Hu, S; Kurhanewicz, J; Larson, PE; Nelson, SJ; Vigneron, DB | 1 |
| Ardenkjaer-Larsen, JH; Glaser, SJ; Haase, A; Janich, MA; Khegai, O; Menzel, MI; Schulte, RF; Schwaiger, M; Weidl, E; Wiesinger, F | 1 |
| Becker, A; Eisenreich, W; Niehaus, K; Pühler, A; Rückert, C; Schatschneider, S; Vorhölter, FJ | 1 |
| Bok, R; Hu, S; Keshari, KR; Kurhanewicz, J; Larson, PE; Reed, G; Shin, P; Vigneron, DB; von Morze, C; Wilson, DM; Yoshihara, HA; Zhu, M | 1 |
| Ghisla, S; Molla, G; Pollegioni, L | 1 |
| Amanullah, A; Hudson, T; Li, J; Vijayasankaran, N; Wong, CL | 1 |
| Giffin, MM; Modesti, L; Raab, RW; Sohaskey, CD; Wayne, LG | 1 |
| Chen, Y; Guo, L; Xu, L; Yang, L; Zhao, W | 1 |
| Ala-Korpela, M; Jula, A; Kähönen, M; Kangas, AJ; Keinänen-Kiukaanniemi, S; Laakso, M; Lehtimäki, T; Mäkinen, VP; Mäntyselkä, P; Saltevo, J; Soininen, P; Tiainen, M; Vanhala, M; Würtz, P | 1 |
| Ardenkjaer-Larsen, JH; Durst, M; Glaser, SJ; Haase, A; Janich, MA; Khegai, O; Menzel, MI; Schulte, RF; Schwaiger, M; Sperl, JI; Weidl, E; Wiesinger, F | 1 |
| Adiga, SK; Atreya, HS; D'Souza, F; Kalthur, G; Kumar, P; Pudakalakatti, SM; Uppangala, S | 1 |
| Asakawa, A; Eto, K; Furuie, S; Inoue, K; Inui, A; Kadowaki, T; Katsura, N; Kobayashi, K; Kuroda, E; Ono, H; Saheki, T; Sinasac, DS; Ushikai, M; Yamamura, K; Yokogawa, M; Yoshidumi, Y | 1 |
| Bazotte, RB; Borba-Murad, GR; da Rocha, AF; de Fatima Silva, F; de Souza, CO; de Souza, HM; Liboni, TF; Miksza, DR; Moreira, CC | 1 |
| Bazotte, RB; Borba-Murad, GR; Cassolla, P; de Morais, H; de Souza, CO; de Souza, HM; Dornellas, AP; Moreira, CC | 1 |
| Bok, RA; Goga, A; Hu, S; Kerr, AB; Kruttwig, K; Kurhanewicz, J; Larson, PE; Nelson, SJ; Pauly, JM; Swisher, CL; Vigneron, DB | 1 |
| Åkeson, P; Ardenkjær-Larsen, JH; Butt, SA; Lauritzen, MH; Laustsen, C; Magnusson, P; Søgaard, LV | 1 |
| Degani, H; Frydman, L; Leftin, A | 1 |
| Gohlke, H; Grieshaber, MK; Hergert, U; Meyer, T; Mulnaes, D; Schmitt, L; Smits, SH | 1 |
| Chen, L; Cui, Z; Fu, W; Liao, X; Luo, Z; Zhou, J | 1 |
| Ardenkjaer-Larsen, JH; Bibby, BM; Flyvbjerg, A; Laustsen, C; Lycke, S; Nørregaard, R; Palm, F; Pedersen, M; Østergaard, JA | 1 |
| Gaunitz, F; Letzien, U; Meixensberger, J; Oppermann, H | 1 |
| Kujach, S; Laskowski, R; Olek, RA; Wnuk, D | 1 |
| Adeva-Andany, M; Ameneiros-Rodríguez, E; Donapetry-García, C; Funcasta-Calderón, R; López-Ojén, M; Rodríguez-Seijas, J; Vila-Altesor, M | 1 |
| Abramov, YA; Ghosh, P; Karmilowicz, MJ; Kumar, R; Martin, V; Martinez, C; Sherman, W; Sirin, S | 1 |
| Coll, M; Fernandez, FJ; Garces, F; López-Estepa, M; Peña-Soler, E; Quintana, JF; Richardson, AJ; Rudd, KE; Vega, MC | 1 |
| Han, SW; Shin, JS | 1 |
| Chavarria, L; Cordoba, J; Lope-Piedrafita, S; Monteagudo, E; Romero-Giménez, J | 1 |
| Klatte, S; Wendisch, VF | 1 |
| An, YJ; Kang, KW; Park, S; Wen, H; Xu, WJ | 1 |
| Ando, I; Fujiwara, M; Imai, Y; Oguma, S; Sato, H; Sato, K; Sekino, H; Takeuchi, K | 1 |
| Alves, MG; Conde, VR; Nunes, AR; Oliveira, PF; Pereira, JA; Ramalhosa, E; Rocha, CS; Silva, BM | 1 |
| Arán, VJ; Marín, C; Muro, B; Navarro, P; Ramírez-Macías, I; Reviriego, F; Rosales, MJ; Sánchez-Moreno, M | 1 |
| Bendotti, C; Cantoni, L; Cimini, S; Keun, HC; Rizzardini, M; Siskos, AP; Valbuena, GN | 1 |
| Koelsch, B; Kurhanewicz, J; Larson, P; Leon Swisher, C; Santos, RD; Sriram, R; Sukumar, S; Vigneron, D; Wang, ZJ | 1 |
| Burgess, SC; Chen, Z; Colca, JR; Finck, BN; Fu, X; Kletzien, RF; McCommis, KS; McDonald, WG | 1 |
| Greenhill, C | 1 |
| Billingsley, K; Hurd, R; Josan, S; Luong, R; Mayer, D; Orduna, J; Park, JM; Pfefferbaum, A; Spielman, D; Yu, L | 1 |
| Alsop, DC; Bhatt, RS; Grant, AK; Lenkinski, RE; Seth, P; Sukhatme, VP; Varma, G; Vinogradov, E; Wang, X | 1 |
| Fidelino, L; Jin, ES; Malloy, CR; Merritt, ME; Moreno, KX; Sherry, AD; Wang, JX | 1 |
| Assmann, M; Bühler, B; Julsing, MK; Ladkau, N; Schmid, A; Schrewe, M | 1 |
| Bertelsen, LB; Juul, T; Laustsen, C; Nielsen, PM; Palm, F | 1 |
| Bertelsen, LB; Kristensen, ML; Laustsen, C; Mikkelsen, E; Nielsen, PM; Nørregaard, R; Qi, H; Stødkilde-Jørgensen, H | 1 |
| Bertelsen, LB; Bøtker, HE; Hansen, ESS; Jørgensen, HS; Laustsen, C; Mikkelsen, E; Nielsen, PM; Nørlinger, TS; Tougaard, RS | 1 |
| Dong, L; Liu, Y | 1 |
| Alves, MG; Barros, A; Casal, S; Dias, TR; Oliveira, PF; Silva, BM; Silva, J; Sousa, M | 1 |
| Cordeiro, CD; Docampo, R; Hekmatyar, SK; Prestegard, JH; Zhuo, Y | 1 |
| Hibino, T; Kageyama, H; Phogosee, S; Waditee-Sirisattha, R | 1 |
| Gordon, JW; Larson, PEZ; Milshteyn, E; Vigneron, DB; von Morze, C; Zhu, Z | 1 |
| Li, Y; Wang, C; Wang, X; Zhang, H | 1 |
| An, R; Chen, C; Chen, J; Huang, F; Jiang, Q; Li, M; Li, T; Li, Y; Sun, J; Sun, Z; Tang, Z; Wu, L; Wu, Z; Xu, Q; Yang, J; Yin, Y; Zhang, X; Zhao, S; Zhen, J; Zhu, W | 1 |
| Hill, PW; Jones, DL | 1 |
| Fábián, I; Simon, F; Szabó, M | 1 |
| Bertelsen, LB; Jessen, N; Kjaergaard, U; Laustsen, C; Mikkelsen, E; Nørlinger, T; Qi, H; Stødkilde-Jørgensen, H; Tougaard, RS | 1 |
| Funk, AM; Hever, T; Khemtong, C; Malloy, CR; Maptue, NR; Sherry, AD; Wen, X | 1 |
| Chen, P; Fang, R; Gupta, N; Liang, X; Shen, B; Xia, N; Yang, S; Ye, S; Yuan, J; Zhao, J; Zhou, Y | 1 |
| Bardeesy, N; Billaud, M; Blervaque, R; Bondurand, N; Delmas, V; Fauvelle, F; Hainaut, P; Lafanechère, L; Larue, L; Lucas, A; Pernet-Gallay, K; Pingault, V; Radu, AG; Schlattner, U; Thibert, C; Torch, S; Tricaud, N | 1 |
| Chen, P; Shi, K; Wang, YY; Xu, JZ; Zhang, F; Zhang, WG | 1 |
| Badur, MG; Cordes, T; Gengatharan, J; Handzlik, MK; Kolar, MJ; Lim, EW; Metallo, CM; Muthusamy, T; Pinto, AFM; Saghatelian, A; Wallace, M; You, L | 1 |
| Du, G; Gong, M; Li, J; Liu, K; Liu, L; Lv, X | 1 |
| Batsios, G; Costello, JF; Gillespie, AM; Larson, PEZ; Luchman, HA; Mukherjee, J; Phillips, JJ; Pieper, RO; Ronen, SM; Viswanath, P | 1 |
| Bartlam, M; Chen, Y; Jia, H; Liu, R; Zhang, Q | 1 |
| Bertolini, GL; Biazi, GR; de Souza Galia, WB; de Souza, HM; Frasson-Uemura, IG; Miksza, DR; Zaia, CTBV; Zaia, DAM | 1 |
| Le, XH; Lee, CP; Millar, AH | 1 |
| Bertelsen, LB; Hansen, ESS; Laustsen, C; Ruf, S; Sadowski, T | 1 |
| Baytas, O; Davidson, SM; DeBerardinis, RJ; Morrow, EM | 1 |
| Li, Y; Ping, Q; Wang, S | 1 |
| Gu, BD; Jia, DX; Jin, LQ; Liu, ZQ; Peng, C; Wang, F; Zhao, R; Zheng, YG | 1 |
| Chen, S; Dixon, R; Hua, C; Li, J; Li, Q; Li, Y; Song, Y; Wang, M; Zhang, H | 1 |
| Arend, C; Denker, N; Dringen, R; Harders, AR | 1 |
| Binay, B; Dedeakayoğulları, H; Demir, Ğ; Jänis, J; Turunen, O; Valjakka, J; Yilmazer, B | 1 |
2 review(s) available for alanine and pyruvic acid
| Article | Year |
|---|---|
[Alanine aminotransferase (ALT)].
Topics: Alanine; Alanine Transaminase; Amino Acid Sequence; Animals; Gluconeogenesis; Humans; Isoenzymes; Molecular Sequence Data; Pyruvates; Pyruvic Acid | 1995 |
Comprehensive review on lactate metabolism in human health.
Topics: Alanine; Carbon Dioxide; Diabetes Mellitus; Glucose; Humans; Lactic Acid; Metabolic Networks and Pathways; Mitochondria; Neoplasms; Oxidation-Reduction; Oxidoreductases; Oxygen; Pyruvic Acid | 2014 |
9 trial(s) available for alanine and pyruvic acid
| Article | Year |
|---|---|
The effects of four different crystalloid bypass pump-priming fluids upon the metabolic response to cardiac operation.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Cardiopulmonary Bypass; Glucagon; Glycerol; Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Insulin; Isotonic Solutions; Lactates; Lactic Acid; Perfusion; Potassium; Potassium Compounds; Prospective Studies; Pyruvates; Pyruvic Acid; Random Allocation; Ringer's Lactate | 1985 |
Opiate receptors and the metabolic response to intravenous glucose.
Topics: Alanine; Blood Glucose; Chlorpropamide; Ethanol; Glucagon; Glucose; Humans; Insulin; Kinetics; Lactates; Lactic Acid; Naloxone; Pyruvates; Pyruvic Acid; Receptors, Opioid | 1982 |
Dichloroacetate inhibits peripheral efflux of pyruvate and alanine during hormonally simulated catabolic stress.
Topics: Adult; Alanine; Dichloroacetic Acid; Epinephrine; Glucagon; Glucose; Humans; Hydrocortisone; Male; Muscle Proteins; Nitrogen; Pyruvates; Pyruvic Acid; Wounds and Injuries | 1993 |
Non-invasive tracing of liver intermediary metabolism in normal subjects and in moderately hyperglycaemic NIDDM subjects. Evidence against increased gluconeogenesis and hepatic fatty acid oxidation in NIDDM.
Topics: Adult; Alanine; Blood Glucose; Carbon Isotopes; Citric Acid; Citric Acid Cycle; Diabetes Mellitus, Type 2; Fatty Acids; Female; Gluconeogenesis; Humans; Indicator Dilution Techniques; Kinetics; Lactic Acid; Liver; Male; Middle Aged; Oxidation-Reduction; Phosphoenolpyruvate; Pyruvate Carboxylase; Pyruvate Dehydrogenase Complex; Pyruvic Acid | 1998 |
Short-term training attenuates muscle TCA cycle expansion during exercise in women.
Topics: Adult; Alanine; Citrate (si)-Synthase; Citric Acid Cycle; Exercise; Female; Glutamic Acid; Glycogen; Heart Rate; Humans; Lactic Acid; Male; Muscle, Skeletal; Oxidation-Reduction; Oxygen Consumption; Phosphocreatine; Physical Fitness; Pulmonary Gas Exchange; Pyruvic Acid; Sex Characteristics | 2003 |
Pyruvate shuttling during rest and exercise before and after endurance training in men.
Topics: Adult; Alanine; Anaerobic Threshold; Body Composition; Carbohydrate Metabolism; Exercise; Exercise Test; Femoral Artery; Femoral Vein; Gas Chromatography-Mass Spectrometry; Glycolysis; Hemodynamics; Humans; Lactic Acid; Male; Muscle, Skeletal; Physical Endurance; Physical Fitness; Pyruvic Acid; Rest | 2004 |
Mechanism of dichloroacetate-induced hypolactatemia in humans with or without cirrhosis.
Topics: Adult; Alanine; C-Peptide; Dichloroacetic Acid; Female; Gas Chromatography-Mass Spectrometry; Glucagon; Humans; Insulin; Kinetics; Lactates; Liver; Liver Cirrhosis; Male; Oxidation-Reduction; Pyruvic Acid | 2004 |
Single sodium pyruvate ingestion modifies blood acid-base status and post-exercise lactate concentration in humans.
Topics: Acid-Base Equilibrium; Adult; Alanine; Bicarbonates; Biomarkers; Blood Glucose; Cross-Over Studies; Double-Blind Method; Exercise; Humans; Hydrogen-Ion Concentration; Lactates; Male; Oxygen Consumption; Pulmonary Gas Exchange; Pyruvic Acid; Sports Nutritional Physiological Phenomena; Young Adult | 2014 |
Pyruvate is an effective substitute for glutamate in regulating porcine nitrogen excretion.
Topics: Alanine; Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Cell Line; Diet; Diet, Protein-Restricted; Dietary Proteins; Dietary Supplements; Energy Metabolism; Epithelial Cells; Glutamic Acid; Intestinal Mucosa; Male; Nitrogen; Oxidation-Reduction; Pyruvic Acid; Swine; Urea | 2018 |
303 other study(ies) available for alanine and pyruvic acid
| Article | Year |
|---|---|
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Exercise intolerance in patients with McArdle's disease or mitochondrial myopathies.
Topics: Adult; Alanine; Ammonia; Energy Metabolism; Exercise Test; Exercise Tolerance; Female; Glycogen Storage Disease Type V; Humans; Lactates; Lactic Acid; Male; Mitochondrial Myopathies; Muscle Contraction; Muscles; Oxygen Consumption; Pulmonary Gas Exchange; Pyruvates; Pyruvic Acid | 1992 |
Reducing-equivalent transfer to the mitochondria during gluconeogenesis and ureogenesis in hepatocytes from rats of different thyroid status.
Topics: Alanine; Animals; Aspartic Acid; Biological Transport; Cells, Cultured; Cytoplasm; Gluconeogenesis; Glutamates; Glutamic Acid; Hydrogen; Hyperthyroidism; Hypothyroidism; Male; Malonates; Mitochondria, Liver; NAD; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Thyroid Gland; Urea | 1992 |
A continuous multistage roller reactor for animal cell culture: 1. Patterns of growth, production and catabolism of a murine hybridoma.
Topics: Alanine; Animals; Antibodies, Monoclonal; Cell Division; Glucose; Glutamine; Hybridomas; Kinetics; Methods; Mice; Pyruvates; Pyruvic Acid | 1990 |
High-performance liquid chromatographic microassay for L-alanine:glyoxylate aminotransferase activity in human liver.
Topics: Alanine; Alanine Transaminase; Chromatography, High Pressure Liquid; Colorimetry; Glyoxylates; Humans; Hyperoxaluria; Kinetics; Liver; Microchemistry; Phenylhydrazines; Pyruvates; Pyruvic Acid; Spectrophotometry; Transaminases | 1992 |
Inactivation of dimeric D-amino acid transaminase by a normal substrate through formation of an unproductive coenzyme adduct in one subunit.
Topics: Alanine; D-Alanine Transaminase; Endopeptidases; Enzyme Activation; Enzyme Reactivators; Hydrogen-Ion Concentration; Kinetics; Pyridoxal Phosphate; Pyridoxamine; Pyruvates; Pyruvic Acid; Spectrometry, Fluorescence; Transaminases | 1992 |
Indole protects tryptophan indole-lyase, but not tryptophan synthase, from inactivation by trifluoroalanine.
Topics: Alanine; Chromatography, High Pressure Liquid; Enzyme Activation; Escherichia coli; Fluorides; Indoles; Kinetics; Magnetic Resonance Spectroscopy; Pyruvates; Pyruvic Acid; Spectrophotometry; Tryptophan Synthase; Tryptophanase | 1992 |
Role of the rat liver in the disposal of a glucose gavage.
Topics: Alanine; Animals; Glucose; Intubation, Gastrointestinal; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Time Factors | 1992 |
[Uncoupling expression of genes coding for the synthesis of proteins involved in transport and utilization of fructose in Escherichia coli K-12].
Topics: Alanine; Bacterial Proteins; Biological Transport; Escherichia coli; Fructose; Gene Expression Regulation, Bacterial; Genes, Bacterial; Lactates; Lactic Acid; Mutation; Operon; Phosphotransferases; Phosphotransferases (Paired Acceptors); Pyruvates; Pyruvic Acid; Xylitol | 1991 |
Products of non-reductive CO2 assimilation in the halophilic archaebacterium Haloferax mediterranei.
Topics: Alanine; Amino Acids; Ammonia; Archaea; Aspartic Acid; Bicarbonates; Carbon Dioxide; Glutamates; Glutamic Acid; Keto Acids; Propionates; Pyruvates; Pyruvic Acid; Sodium; Sodium Bicarbonate | 1991 |
Effect of obesity on circulating intermediary metabolite concentrations in the absence of impaired glucose tolerance.
Topics: Adult; Alanine; Blood Glucose; Body Mass Index; C-Peptide; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; Glycerol; Humans; Insulin; Ketone Bodies; Lactates; Male; Middle Aged; Obesity; Obesity, Morbid; Pyruvates; Pyruvic Acid; Regression Analysis | 1991 |
[Biochemical modifications in stress ischemia of the calf muscles].
Topics: Alanine; Ammonia; Energy Metabolism; Humans; Hypoxanthine; Hypoxanthines; Intermittent Claudication; Ischemia; Lactates; Lactic Acid; Leg; Male; Middle Aged; Muscles; Pyruvates; Pyruvic Acid | 1991 |
Isotopic evaluation of the metabolism of pyruvate and related substrates in normal adult volunteers and severely burned children: effect of dichloroacetate and glucose infusion.
Topics: Absorption; Adult; Alanine; Burns; Carbon Isotopes; Child; Child, Preschool; Dichloroacetic Acid; Energy Metabolism; Glucose; Humans; Infusions, Intravenous; Lactates; Lactic Acid; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Reference Values | 1991 |
Evaluation of interconversion between (R)- and (S)-enantiomers of beta-aminoisobutyrate.
Topics: 4-Aminobutyrate Transaminase; Alanine; Aminoisobutyric Acids; Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Ketoglutaric Acids; Pyruvates; Pyruvic Acid; Rats; Stereoisomerism; Transaminases | 1990 |
Stimulation of alanine metabolism by ammonia in the perfused rat liver. Quantitative analysis by means of a mathematical model.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Ammonium Chloride; Animals; Caprylates; Energy Metabolism; Female; Gluconeogenesis; Glucose; Hydroxybutyrates; Kinetics; Lactates; Lactic Acid; Liver; Mathematics; Models, Biological; NAD; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Urea | 1991 |
Maximal activity of phosphate-dependent glutaminase and glutamine metabolism in septic rats.
Topics: Alanine; Animals; Arteries; Glutaminase; Glutamine; Intestinal Mucosa; Kidney; Lactates; Lactic Acid; Liver; Lymph Nodes; Lymphocytes; Male; Phosphates; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sepsis; Veins | 1991 |
Diurnal pattern of plasma metformin concentrations and its relation to metabolic effects in type 2 (non-insulin-dependent) diabetic patients.
Topics: Alanine; Blood Glucose; Butyrates; Butyric Acid; Circadian Rhythm; Diabetes Mellitus, Type 2; Glycerol; Humans; Lactates; Lactic Acid; Metformin; Pyruvates; Pyruvic Acid | 1990 |
Possible involvement of alanine and pyruvate in the regulation of glucose transport in heart muscle cells.
Topics: Alanine; Animals; Biological Transport, Active; Calcium; Cells, Cultured; Deoxyglucose; Female; Heart; Kinetics; Myocardium; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Serine; Valine | 1990 |
Carbohydrate utilization in exercising muscle in subtotally nephrectomized rabbits.
Topics: Alanine; Animals; Carbohydrate Metabolism; Glutamine; Glycogen; Ketoglutaric Acids; Kidney; Kidney Failure, Chronic; Lactates; Lactic Acid; Muscles; Nephrectomy; Physical Exertion; Pyruvates; Pyruvic Acid; Rabbits | 1990 |
Pyruvate utilization of rabbit reticulocytes--a compartmental study.
Topics: Alanine; Animals; Aspartic Acid; Cell Compartmentation; Citric Acid Cycle; Decarboxylation; Glutamine; Kinetics; Mitochondria; Pyruvates; Pyruvic Acid; Rabbits; Reticulocytes | 1990 |
Stimulation of mitochondrial pyruvate transport in rat renal cortex by phenylephrine.
Topics: Alanine; Animals; Biological Transport; Coumaric Acids; Gluconeogenesis; Ketoglutaric Acids; Kidney Cortex; Liver; Mitochondria; Phenylephrine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1990 |
Metabolic profiles in patients with insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Alanine; Blood Glucose; Fatty Acids, Nonesterified; Female; Glycerol; Humans; Insulin; Insulinoma; Ketone Bodies; Lactates; Lactic Acid; Male; Middle Aged; Pancreatic Neoplasms; Pyruvates; Pyruvic Acid | 1989 |
Stimulation of glutamine metabolism by the antiepileptic drug, sodium valproate, in isolated dog kidney tubules.
Topics: Alanine; Ammonia; Animals; Aspartic Acid; Dogs; Female; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Glutaminase; Glutamine; Kidney Tubules; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Valproic Acid | 1989 |
Whole body and regional fuel metabolism during early postexercise recovery.
Topics: Adult; Alanine; Amino Acids, Branched-Chain; Blood Glucose; Calorimetry, Indirect; Energy Metabolism; Exercise; Fatty Acids, Nonesterified; Female; Glucose; Glycerol; Humans; Insulin; Lactates; Lactic Acid; Lipid Metabolism; Male; Muscles; Norepinephrine; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1989 |
Metabolic effects of three ketogenic diets in the treatment of severe epilepsy.
Topics: Adolescent; Adult; Alanine; Blood Glucose; Child; Child, Preschool; Dietary Fats; Energy Metabolism; Epilepsy; Glycerol; Humans; Insulin; Ketone Bodies; Lactates; Lactic Acid; Middle Aged; Pyruvates; Pyruvic Acid; Triglycerides; Uric Acid | 1989 |
Metabolic control of hepatic gluconeogenesis in response to sepsis.
Topics: Alanine; Animals; Bacterial Infections; Blood Glucose; Body Temperature; Body Weight; Fatty Acids, Nonesterified; Glucagon; Gluconeogenesis; Hemodynamics; Insulin; Ketone Bodies; Lactates; Liver; Male; Organ Size; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1989 |
Persistent abnormalities of the metabolism of an oral glucose load in insulin-treated type I diabetics.
Topics: Administration, Oral; Alanine; Blood Glucose; Calorimetry, Indirect; Diabetes Mellitus, Type 1; Forearm; Glucose; Humans; Insulin; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1989 |
Effects of hyperthermia on the peripheral metabolism of ammonia and glutamine.
Topics: Acid-Base Equilibrium; Alanine; Ammonia; Arteries; Blood Glucose; Body Temperature; Fatty Acids, Nonesterified; Female; Fever; Forearm; Glutamine; Humans; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1989 |
Influence of peripheral arterial occlusive disease on muscular metabolism. Part 2: Changes in pyruvate, alanine, and urea concentration in femoral blood.
Topics: Alanine; Arterial Occlusive Diseases; Exercise Test; Humans; Ischemia; Leg; Muscle Contraction; Muscles; Pyruvates; Pyruvic Acid; Urea | 1989 |
The mechanism by which adenosine decreases gluconeogenesis from lactate in isolated rat hepatocytes.
Topics: Adenine Nucleotides; Adenosine; Alanine; Animals; Cyclic AMP; Gluconeogenesis; In Vitro Techniques; Ketone Bodies; Lactates; Lactic Acid; Liver; Phosphates; Pyruvates; Pyruvic Acid; Rats | 1987 |
Effect of protein intake on amino acid catabolism and gluconeogenesis by isolated hepatocytes from the cat (Felis domestica).
Topics: Alanine; Amino Acids; Animals; Cats; Dietary Proteins; Gluconeogenesis; Glutamine; Kinetics; Liver; Pyruvates; Pyruvic Acid; Threonine; Tryptophan Oxygenase; Tyrosine Transaminase; Urea | 1985 |
Pathway of ammonium assimilation in Streptomyces venezuelae examined by amino acid analyses and 15N nuclear magnetic resonance spectroscopy.
Topics: Alanine; Ammonium Sulfate; Anaerobiosis; Glutamates; Glutamic Acid; Glutamine; Ketoglutaric Acids; Magnetic Resonance Spectroscopy; Nitrogen Radioisotopes; Pyruvates; Pyruvic Acid; Species Specificity; Streptomyces | 1985 |
The metabolic response of the kidney to acute sodium lactate alkalosis.
Topics: Alanine; Alanine Transaminase; Alkalosis; Animals; Dogs; Glomerular Filtration Rate; Glutamates; Glutamic Acid; Glutamine; Kidney; Kidney Cortex; Lactates; Lactic Acid; Liver; Muscles; Pyruvates; Pyruvic Acid | 1985 |
Transamination pathways influencing L-glutamine and L-glutamate oxidation by rat enterocyte mitochondria and the subcellular localization of L-alanine aminotransferase and L-aspartate aminotransferase.
Topics: Alanine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Intestinal Mucosa; Intestines; Malates; Male; Mitochondria; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Subcellular Fractions | 1985 |
An anabolic state in the heart induced by arginine intubation.
Topics: Alanine; Animals; Arginine; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Myocardium; Ornithine; Perfusion; Phenylalanine; Pyruvates; Pyruvic Acid; Rats | 1987 |
Significance of the alanine aminotransferase reaction in the formation of alpha-ketoglutarate in rat liver mitochondria.
Topics: Alanine; Alanine Transaminase; Animals; Aspartic Acid; Citrates; Citric Acid; Glutamates; Glutamic Acid; Ketoglutaric Acids; Malates; Male; Mitochondria, Liver; Oxaloacetates; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1988 |
Pathways for organic osmolyte synthesis in rabbit renal papillary tissue, a metabolic study using 13C-labeled substrates.
Topics: Alanine; Aldehyde Reductase; Animals; Citric Acid Cycle; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycerylphosphorylcholine; Glycolysis; Inositol; Kidney Medulla; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Osmolar Concentration; Pyruvates; Pyruvic Acid; Rabbits; Sorbitol | 1988 |
The effect of ketone bodies on alanine and glutamine metabolism in isolated skeletal muscle from the fasted chick.
Topics: Alanine; Amino Acids, Branched-Chain; Animals; Aspartic Acid; Chickens; Fasting; Glucose; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Intracellular Fluid; Ketone Bodies; Muscles; Pyruvates; Pyruvic Acid | 1988 |
Localization and role of pyruvate kinase isoenzymes in the regulation of carbohydrate metabolism and pyruvate recycling in rat kidney cortex.
Topics: Alanine; Animals; Bucladesine; Calcium; Carbohydrate Metabolism; Gluconeogenesis; Glucose; Immune Sera; Isoenzymes; Kidney Cortex; Lactates; Lactic Acid; Male; Parathyroid Hormone; Phosphoenolpyruvate; Phosphoenolpyruvate Carboxykinase (GTP); Phosphorylation; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rabbits; Rats; Sheep | 1986 |
Perchloric acid interference in enzymatic-fluorimetric-continuous-flow assay methods for measuring glucose, lactate, pyruvate, alanine, glycerol, and 3-hydroxybutyrate in blood.
Topics: 3-Hydroxybutyric Acid; Alanine; Autoanalysis; Blood Glucose; Glycerol; Humans; Hydroxybutyrates; Lactates; Lactic Acid; Perchlorates; Pyruvates; Pyruvic Acid | 1986 |
Characterization of the specific pyruvate transport system in Escherichia coli K-12.
Topics: Alanine; Biological Transport, Active; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Escherichia coli; Kinetics; Lactates; Lactic Acid; Methylphenazonium Methosulfate; Phosphotransferases; Phosphotransferases (Paired Acceptors); Pyruvates; Pyruvic Acid; Time Factors | 1987 |
Effect of insulin on the metabolic distribution of carbons 1, 2, and 3 of pyruvate.
Topics: Alanine; Animals; Carbon; Carbon Dioxide; Citric Acid Cycle; Insulin; Lipid Metabolism; Liver; Male; Oxidation-Reduction; Proteins; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
D-lactate production by Leishmania braziliensis through the glyoxalase pathway.
Topics: Alanine; Anaerobiosis; Animals; Carbon-Oxygen Lyases; Glucose; Glycerol; Lactates; Lactoylglutathione Lyase; Leishmania; Leishmania braziliensis; Lyases; Movement; Phenylglyoxal; Pyruvaldehyde; Pyruvates; Pyruvic Acid; Ribose; Sonication; Thiolester Hydrolases | 1988 |
Formation of some extracellular enzymes during the exponential growth of Bacillus subtilis.
Topics: Alanine; alpha-Amylases; Bacillus subtilis; Endopeptidases; Extracellular Space; Kinetics; Metalloendopeptidases; Pyruvates; Pyruvic Acid; Serine Endopeptidases | 1988 |
Modulation of the amino acid control of hepatic protein degradation by caloric deprivation. Two modes of alanine co-regulation.
Topics: Alanine; Amino Acids; Animals; Caprylates; Fasting; Lactates; Lactic Acid; Liver; Male; Perfusion; Proteins; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Lew; Reference Values | 1988 |
Muscle glycogen repletion during active postexercise recovery.
Topics: Alanine; Blood Glucose; Glycogen; Humans; Hydrogen-Ion Concentration; Insulin; Lactates; Lactic Acid; Male; Muscles; Physical Exertion; Pyruvates; Pyruvic Acid | 1987 |
13C-NMR analysis of Aspergillus mutants disturbed in pyruvate metabolism.
Topics: Acetates; Alanine; Aspergillus nidulans; Carbon Radioisotopes; Fructose; Glucose; Magnetic Resonance Spectroscopy; Pyruvate Carboxylase; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Sucrose | 1987 |
Effect of exercise on net hepatic uptake of lactate, pyruvate, alanine, and glycerol in sheep.
Topics: Alanine; Animals; Blood Glucose; Glucagon; Gluconeogenesis; Glycerol; Insulin; Lactates; Lactic Acid; Liver; Physical Exertion; Pyruvates; Pyruvic Acid; Regional Blood Flow; Sheep | 1987 |
Metabolic interactions of parenchymal hepatocytes and dividing epithelial cells in co-culture.
Topics: Adult; Alanine; Albumins; Animals; Carnitine O-Palmitoyltransferase; Cells, Cultured; Epithelial Cells; Epithelium; Female; Glucose; Humans; Ketone Bodies; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Male; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1988 |
Clinical and laboratory observations in a child with hepatic phosphorylase kinase deficiency.
Topics: 3-Hydroxybutyric Acid; Alanine; Blood Glucose; Child, Preschool; Glycogen Storage Disease; Histocytochemistry; Humans; Hydroxybutyrates; Ketosis; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; Phosphorylase Kinase; Pyruvates; Pyruvic Acid | 1986 |
Release of L-alanine by tumor cells.
Topics: Alanine; Animals; Cell Line; Glucose; Lactates; Lactic Acid; Leukemia L5178; Leukemia, Experimental; Lymphocyte Activation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Pyruvates; Pyruvic Acid; T-Lymphocytes, Cytotoxic | 1986 |
Suppression of cytotoxic T-lymphocyte activation by pyruvate and L-alanine.
Topics: Alanine; Animals; Cells, Cultured; Cytotoxicity, Immunologic; DNA; Lymphocyte Activation; Mice; Pyruvates; Pyruvic Acid; T-Lymphocytes, Cytotoxic | 1986 |
Intermediary metabolism in diabetic dogs treated with pancreatic autotransplants and insulin pumps.
Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Diabetes Mellitus, Experimental; Dogs; Fatty Acids, Nonesterified; Hydroxybutyrates; Insulin; Insulin Infusion Systems; Lactates; Lactic Acid; Pancreas Transplantation; Pyruvates; Pyruvic Acid; Transplantation, Autologous | 1986 |
Metabolic effects of low-dose incremental insulin infusion in diabetic man.
Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glycerol; Humans; Hydroxybutyrates; Insulin; Insulin Infusion Systems; Ketone Bodies; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Time Factors | 1986 |
The metabolic and hormonal adaptations of normal dogs to long-term exogenous sulfated insulin infusions.
Topics: 3-Hydroxybutyric Acid; Adaptation, Physiological; Alanine; Animals; Blood Glucose; Circadian Rhythm; Dogs; Fatty Acids, Nonesterified; Gastric Inhibitory Polypeptide; Gastrins; Glucagon; Hydroxybutyrates; Insulin; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Sulfates; Time Factors | 1986 |
Key role of L-alanine in the control of hepatic protein synthesis.
Topics: Alanine; Amino Acids; Animals; Glucose; Liver; Male; Peptide Chain Elongation, Translational; Polyribosomes; Protein Biosynthesis; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Starvation | 1987 |
Carbohydrate utilization by exercising muscle following pre-exercise glucose ingestion.
Topics: Adult; Alanine; Blood Glucose; Glucose; Glycogen; Humans; Lactates; Lactic Acid; Leg; Male; Muscles; Oxygen Consumption; Physical Exertion; Pyruvates; Pyruvic Acid | 1987 |
Effects of alanine on malate-aspartate shuttle in perfused livers from cold-exposed rats.
Topics: Adrenalectomy; Alanine; Alanine Transaminase; Aminooxyacetic Acid; Animals; Asparagine; Aspartic Acid; Cold Temperature; Dexamethasone; Ethanol; Glucose; Lactates; Lactic Acid; Liver; Malates; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sorbitol | 1986 |
Rate-limiting steps for hepatic gluconeogenesis. Mechanism of oxamate inhibition of mitochondrial pyruvate metabolism.
Topics: Alanine; Amino Acids; Animals; Gluconeogenesis; Kinetics; Malates; Male; Mitochondria, Liver; Oxamic Acid; Pyruvate Carboxylase; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
A reexamination of the role of the cytosolic alanine aminotransferase in hepatic gluconeogenesis.
Topics: Acetates; Acetic Acid; Alanine; Alanine Transaminase; Animals; Carbon Dioxide; Cinnamates; Cytosol; Gluconeogenesis; Isoenzymes; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; Monocarboxylic Acid Transporters; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1985 |
Utilization of pyruvate and pyruvate precursors by normal and carcinogen-altered rat tracheal epithelial cells in culture.
Topics: Alanine; Animals; Carbon Radioisotopes; Cells, Cultured; Glucose; Glutamine; Glycolysis; Lactates; Lactic Acid; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Trachea; Tracheal Neoplasms | 1986 |
Role of the availability of substrates on hepatic and renal gluconeogenesis in the fasted late pregnant rat.
Topics: Alanine; Animals; Carbon Radioisotopes; Fasting; Female; Gluconeogenesis; Glucose; Glycerol; In Vitro Techniques; Kidney; Liver; Maternal-Fetal Exchange; Pregnancy; Pregnancy, Animal; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
Studies on the site of the block in gluconeogenesis causing severe hypoglycemia in intestinal ischemia shock in rats.
Topics: Adenosine Triphosphate; Alanine; Animals; Epinephrine; Female; Glucagon; Gluconeogenesis; Hypoglycemia; Intestines; Ischemia; NAD; Norepinephrine; Portal Vein; Pyruvates; Pyruvic Acid; Rats; Shock, Hemorrhagic | 1985 |
The concentration of blood components related to fuel metabolism during prolonged fasting in children.
Topics: Adolescent; Age Factors; Alanine; Blood Chemical Analysis; Blood Glucose; Child; Child, Preschool; Energy Metabolism; Fasting; Fatty Acids, Nonesterified; Female; Humans; Ketone Bodies; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Sex Factors; Time Factors; Triglycerides | 1985 |
Role of pyruvate carboxylation in the energy-linked regulation of pool sizes of tricarboxylic acid-cycle intermediates in the myocardium.
Topics: Alanine; Animals; Aspartic Acid; Bicarbonates; Citrates; Citric Acid; Citric Acid Cycle; Female; Glutamates; Glutamic Acid; Heart Arrest; In Vitro Techniques; Ketoglutaric Acids; Kinetics; Malates; Mitochondria, Heart; Myocardium; Potassium Chloride; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1982 |
Lactate, alanine and glutamine metabolism in isolated canine pup liver cells.
Topics: Alanine; Ammonia; Animals; Dogs; Female; Glucose; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Urea | 1983 |
The metabolic effects of dopamine in man.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Catecholamines; Dopamine; Fatty Acids, Nonesterified; Glucagon; Glycerol; Growth Hormone; Hemodynamics; Humans; Hydroxybutyrates; Insulin; Lactates; Lactic Acid; Male; Metabolism; Pyruvates; Pyruvic Acid; Somatostatin | 1984 |
Metabolic effects of adrenaline and noradrenaline in man: studies with somatostatin.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glycerol; Growth Hormone; Humans; Hydroxybutyrates; Insulin; Lactates; Lactic Acid; Male; Norepinephrine; Pyruvates; Pyruvic Acid; Somatostatin | 1984 |
The role of phosphoenolpyruvate carboxykinase in muscle alanine synthesis.
Topics: Alanine; Animals; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Lactates; Lactic Acid; Male; Muscles; Phosphoenolpyruvate Carboxykinase (GTP); Picolinic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Starvation; Substrate Specificity | 1984 |
Observation of carbon labelling in cell metabolites using proton spin echo NMR.
Topics: Alanine; Alanine Transaminase; Animals; Carbon Isotopes; Electron Spin Resonance Spectroscopy; Isotope Labeling; Magnetic Resonance Spectroscopy; Myocardium; Pyruvates; Pyruvic Acid; Swine | 1982 |
Metabolic effects of moderate alcohol intake with meals in insulin-dependent diabetics controlled by artificial endocrine pancreas (AEP) and in normal subjects.
Topics: Adult; Alanine; Alcohol Drinking; Blood Glucose; Diabetes Mellitus; Diet; Ethanol; Fatty Acids, Nonesterified; Glucagon; Glycerol; Humans; Insulin; Insulin Infusion Systems; Ketone Bodies; Lactates; Pyruvates; Pyruvic Acid; Wine | 1983 |
Metabolic effects of intensified insulin therapy.
Topics: Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Drug Administration Schedule; Fatty Acids, Nonesterified; Glycerol; Humans; Hypoglycemia; Injections, Jet; Insulin; Insulin Infusion Systems; Lactates; Pyruvates; Pyruvic Acid | 1984 |
The response of blood intermediary metabolite levels to 24 hours treatment with a blood glucose-controlled insulin infusion system in type 1 diabetes.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glycerol; Humans; Hydroxybutyrates; Insulin; Insulin Infusion Systems; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Time Factors | 1984 |
Metabolic compartmentation of pyruvate in the isolated perfused rat heart.
Topics: Alanine; Animals; Carbon Dioxide; Cell Compartmentation; Glucose; In Vitro Techniques; Lactates; Lactic Acid; Male; Mitochondria, Heart; Models, Biological; Myocardium; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1983 |
Precursor of carbon atom five and hydroxymethyl carbon atom of the pyrimidine moiety of thiamin in Escherichia coli.
Topics: Alanine; Escherichia coli; Glycerol; Pyrimidines; Pyruvates; Pyruvic Acid; Ribonucleotides; Serine; Thiamine | 1983 |
Regulation of the glycine cleavage system in the isolated perfused rat liver.
Topics: Acetoacetates; Alanine; Ammonium Chloride; Animals; Carbon Dioxide; Glycine; Kinetics; Liver; Male; Oxidation-Reduction; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
Changes in blood glucose levels in relation to blood ketone body ratio following hypertonic glucose infusion in 70% hepatectomized rabbits.
Topics: Alanine; Animals; Bilirubin; Blood Glucose; Cholestasis; Citric Acid Cycle; Glucose; Glucose Solution, Hypertonic; Hepatectomy; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Postoperative Complications; Postoperative Period; Pyruvates; Pyruvic Acid; Rabbits; Time Factors | 1984 |
Requirement for alanine in the amino acid control of deprivation-induced protein degradation in liver.
Topics: Alanine; Amino Acids; Animals; Caprylates; Lactates; Lactic Acid; Liver; Male; Proteins; Pyruvates; Pyruvic Acid; Rats; Starvation | 1984 |
L-amino acids from a racemic mixture of alpha-hydroxy acids.
Topics: Alanine; Alanine Dehydrogenase; Amino Acid Oxidoreductases; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Pyruvates; Pyruvic Acid; Stereoisomerism | 1984 |
Enzymatic synthesis of [1-11C]pyruvic acid, L-[1-11C]lactic acid and L-[1-11C]alanine via DL-[1-11C]alanine.
Topics: Alanine; Carbon Radioisotopes; Enzymes, Immobilized; Isotope Labeling; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Tomography, Emission-Computed | 1984 |
Splanchnic glucose metabolism during leg exercise in 60-hour-fasted human subjects.
Topics: Adult; Alanine; Blood Glucose; Fasting; Fatty Acids, Nonesterified; Glucose; Glycerol; Humans; Ketone Bodies; Kinetics; Lactates; Lactic Acid; Liver; Male; Physical Exertion; Pyruvates; Pyruvic Acid; Splanchnic Circulation | 1983 |
Comparison of the kinetics and utilisation of D(-)-and L(+)-sodium lactate in normal man.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Alanine; Female; Humans; Hydroxybutyrates; Kinetics; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Stereoisomerism | 1983 |
Effects of fenfluramine on hepatic intermediary metabolism.
Topics: Acetyl Coenzyme A; Alanine; Animals; Fatty Acids; Fenfluramine; Gluconeogenesis; Glycolysis; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1983 |
The stimulation of mitochondrial pyruvate carboxylation after dexamethasone treatment of rats.
Topics: Adrenalectomy; Alanine; Animals; Biological Transport; Coumaric Acids; Cycloheximide; Dexamethasone; Ketoglutaric Acids; Male; Mitochondria, Liver; Pyruvate Carboxylase; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Stimulation, Chemical; Temperature | 1984 |
The stimulation of hepatic gluconeogenesis by acetoacetate precursors. A role for the monocarboxylate translocator.
Topics: 3-Hydroxybutyric Acid; Acetates; Acetoacetates; Alanine; Animals; Gluconeogenesis; Hydroxybutyrates; In Vitro Techniques; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Perfusion; Pyruvate Decarboxylase; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
The metabolic and hormonal response to acute normoglycaemia in type 1 (insulin-dependent) diabetes: studies with a glucose controlled insulin infusion system (artificial endocrine pancreas).
Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; Humans; Insulin; Insulin Infusion Systems; Ketone Bodies; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1982 |
The effect of diet on intermediary metabolite concentrations in Type 2 (non-insulin-dependent) diabetes mellitus.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Alanine; Diabetes Mellitus; Female; Glycerol; Humans; Hydroxybutyrates; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Time Factors | 1983 |
Effect of postnatal hypoxia on the energy homeostasis of the newborn rat during the early neonatal period.
Topics: Adenine Nucleotides; Alanine; Animals; Animals, Newborn; Blood Glucose; Energy Metabolism; Glucagon; Homeostasis; Hypoxia; Lactates; Lactic Acid; Liver; Liver Glycogen; Oxygen; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1983 |
Studies on pyruvate carboxylase, pyruvate decarboxylase and lipoamide dehydrogenase in subacute necrotizing encephalomyelopathy.
Topics: Alanine; Brain Diseases; Carboxy-Lyases; Cells, Cultured; Dihydrolipoamide Dehydrogenase; Female; Fibroblasts; Humans; Infant; Lactates; Lactic Acid; Male; Necrosis; Pyruvate Carboxylase; Pyruvate Decarboxylase; Pyruvates; Pyruvic Acid | 1982 |
Effects of pregnancy and sex steroid administration on skeletal muscle metabolism in the rat.
Topics: Alanine; Animals; Estradiol; Female; Glucose; Glycerol; Insulin; Lactates; Lactic Acid; Muscles; Oxygen Consumption; Phenylalanine; Pregnancy; Pregnancy, Animal; Progesterone; Pyruvates; Pyruvic Acid; Rats | 1981 |
Insulin "inhibition" of gluconeogenesis by stimulation of protein synthesis.
Topics: Alanine; Animals; Blood Glucose; Gluconeogenesis; Glycerol; Insulin; Lactates; Lactic Acid; Male; Protein Biosynthesis; Pyruvates; Pyruvic Acid; Rabbits | 1981 |
Impaired lactate utilization in livers of rats fed high protein-diets.
Topics: Alanine; Animals; Blood Glucose; Dietary Proteins; Gluconeogenesis; Intestinal Absorption; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats | 1982 |
Intracellular compartmentation and control of alanine metabolism in rat liver parenchymal cells.
Topics: Alanine; Animals; Cytosol; In Vitro Techniques; Lactates; Lactic Acid; Liver; Mitochondria, Liver; Oleic Acid; Oleic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Subcellular Fractions; Thermodynamics | 1982 |
Pyruvate carboxylation as an anaplerotic mechanism in the isolated perfused rat heart.
Topics: Acetates; Alanine; Animals; Citrates; Citric Acid; Citric Acid Cycle; Female; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Malates; Myocardium; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1982 |
A simple, rapid method for the determination of glucose, lactate, pyruvate, alanine, 3-hydroxybutyrate and acetoacetate on a single 20-mul blood sample.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Blood Glucose; Fluorometry; Humans; Hydroxybutyrates; Keto Acids; Lactates; Lactic Acid; Methods; Microchemistry; NAD; Physical Exertion; Pyruvates; Pyruvic Acid; Spectrophotometry; Starvation | 1982 |
Accumulation and disposal of tricarboxylic acid cycle intermediates during propionate oxidation in the isolated perfused rat heart.
Topics: Alanine; Animals; Biological Transport; Carbon Radioisotopes; Citric Acid Cycle; Female; In Vitro Techniques; Lactates; Lactic Acid; Myocardium; Oxidation-Reduction; Perfusion; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1982 |
Pathophysiology of metabolic acidosis: effect of low pH on the hepatic uptake of lactate, pyruvate and alanine.
Topics: Acidosis; Alanine; Animals; Blood Glucose; Female; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Liver; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1982 |
Influence of abdominal surgical trauma on substrate utilization by the human brain.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Brain; Cholecystectomy; Female; Glucose; Glycerol; Humans; Hydroxybutyrates; Lactates; Lactic Acid; Male; Middle Aged; Oxygen Consumption; Pyruvates; Pyruvic Acid; Surgical Procedures, Operative | 1981 |
The conversion of alanine into glutamine in guinea-pig renal cortex. Essential role of pyruvate carboxylase.
Topics: Alanine; Alanine Transaminase; Animals; Fluoroacetates; Glutamine; Guinea Pigs; In Vitro Techniques; Ketoglutaric Acids; Kidney Cortex; Kidney Tubules; Pyruvate Carboxylase; Pyruvates; Pyruvic Acid | 1981 |
Metabolism of [3-13C]pyruvate and [3-13C]propionate in normal and ischaemic rat heart in vivo: 1H- and 13C-NMR studies.
Topics: Acetyl Coenzyme A; Alanine; Animals; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Myocardium; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1995 |
Presentation and clinical investigation of mitochondrial respiratory chain disease. A study of 51 patients.
Topics: Adolescent; Adult; Alanine; Brain; Child; Creatine Kinase; DNA, Mitochondrial; Electroencephalography; Electromyography; Electron Transport; Electron Transport Complex IV; Humans; Lactates; Lactic Acid; Mitochondrial Encephalomyopathies; Pyruvates; Pyruvic Acid; Sarcolemma | 1995 |
Cytokines inhibit fatty acid oxidation in isolated rat hepatocytes: synergy among TNF, IL-6, and IL-1.
Topics: Acetyl Coenzyme A; Alanine; Animals; Cells, Cultured; Citric Acid Cycle; Depression, Chemical; Drug Synergism; Energy Metabolism; Fatty Acids; Interleukin-1; Interleukin-6; Ketone Bodies; Liver; Malonyl Coenzyme A; Models, Biological; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1994 |
Hormone effects on hepatic substrate preference in sepsis.
Topics: Alanine; Animals; Energy Metabolism; Gluconeogenesis; Hormones; Lactates; Lactic Acid; Liver; Male; Oxidation-Reduction; Oxygen Consumption; Peritonitis; Phenylephrine; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Sepsis; Substrate Specificity; Urea | 1994 |
Mitochondrial pyruvate metabolism in liver and kidney during acidosis.
Topics: Acidosis; Alanine; Ammonium Chloride; Animals; Fasting; Gluconeogenesis; Kidney Cortex; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Mitochondria; Mitochondria, Liver; Physical Conditioning, Animal; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1994 |
Glycopeptide resistance mediated by enterococcal transposon Tn1546 requires production of VanX for hydrolysis of D-alanyl-D-alanine.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Carbon-Oxygen Ligases; Dipeptides; DNA Transposable Elements; Drug Resistance, Microbial; Enterococcus faecium; Gene Expression Regulation, Bacterial; Genes, Bacterial; Hydrolysis; Lactates; Ligases; Molecular Sequence Data; Peptidoglycan; Protein Kinases; Pyruvates; Pyruvic Acid; Serine-Type D-Ala-D-Ala Carboxypeptidase; Teicoplanin; Transcription Factors; Vancomycin | 1994 |
Metabolic flux determination in C6 glioma cells using carbon-13 distribution upon [1-13C]glucose incubation.
Topics: Alanine; Aspartic Acid; Carbon Isotopes; Citric Acid Cycle; Glioma; Gluconeogenesis; Glucose; Glutamates; Glutamic Acid; Glycogen; Glycolysis; Kinetics; Magnetic Resonance Spectroscopy; Malate Dehydrogenase; Mathematics; Models, Biological; Pentose Phosphate Pathway; Perchlorates; Pyruvates; Pyruvic Acid; Tumor Cells, Cultured | 1993 |
Isotopomer studies of gluconeogenesis and the Krebs cycle with 13C-labeled lactate.
Topics: Acetyl Coenzyme A; Alanine; Animals; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Citric Acid Cycle; Gas Chromatography-Mass Spectrometry; Gluconeogenesis; Glucose; Glutamates; Glutamic Acid; Glutamine; Isotope Labeling; Lactates; Lactic Acid; Liver; Male; Oxaloacetates; Phosphoenolpyruvate; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1993 |
Tetrazole isosteres of biologically active acids and their effects on enzymes.
Topics: Alanine; Alcohol Dehydrogenase; Animals; Benzoates; Benzoic Acid; Carboxylic Acids; D-Amino-Acid Oxidase; Esters; Kinetics; L-Lactate Dehydrogenase; Muscles; Oxidation-Reduction; Oxidoreductases; Pyruvates; Pyruvic Acid; Rabbits; Spectrophotometry, Ultraviolet; Tetrazoles | 1994 |
Generation of C3- and C2-deuterated L-lactic acid by human erythrocytes exposed to D-[1-13C]glucose, D-[2-13C]glucose and D-[6-13C]glucose in the presence of D2O.
Topics: Alanine; Alanine Transaminase; Carbon Isotopes; Deuterium; Erythrocytes; Glucose; Glycolysis; Humans; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvates; Pyruvic Acid | 1994 |
Substrate cycling between pyruvate and oxaloacetate in awake normal and 3,3'-5-triiodo-L-thyronine-treated rats.
Topics: Alanine; Animals; Glucose; Liver; Malate Dehydrogenase; Male; Oxaloacetates; Pyruvate Carboxylase; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reference Values; Substrate Cycling; Time Factors; Triiodothyronine | 1994 |
Measured and predicted values of oxygen consumption during isoflurane anesthesia in man.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Anesthesia, Inhalation; Blood Glucose; Cardiac Output; Female; Hemoglobins; Humans; Isoflurane; Lactates; Lactic Acid; Male; Middle Aged; Oxygen; Oxygen Consumption; Pyruvates; Pyruvic Acid; Thermodilution | 1994 |
Pyruvate metabolism in Halobacterium salinarium studied by intracellular 13C nuclear magnetic resonance spectroscopy.
Topics: Alanine; Carbon Isotopes; Citric Acid Cycle; Halobacterium; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvates; Pyruvic Acid | 1994 |
Alanine as a lipogenic precursor in isolated hepatocytes from obese Zucker rats.
Topics: Acetyl Coenzyme A; Alanine; Alanine Transaminase; Animals; Cells, Cultured; Citrates; Coumaric Acids; Fatty Acids; Glucose; Lactates; Lactic Acid; Leucine; Lipids; Liver; Liver Glycogen; Male; Mitochondria, Liver; Obesity; Pyruvates; Pyruvic Acid; Rats; Rats, Zucker | 1993 |
Tests of the ability of two-cell mouse embryos to utilize selected precursors of phosphoenolpyruvic acid and pyruvic acid.
Topics: Alanine; Animals; Culture Media; Culture Techniques; Embryo, Mammalian; Embryonic and Fetal Development; Energy Metabolism; Female; Glyceric Acids; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Phosphoenolpyruvate; Pyruvates; Pyruvic Acid; Serine | 1993 |
Factors affecting detection of Brucella melitensis by BACTEC NR730, a nonradiometric system for hemocultures.
Topics: Alanine; Bacteremia; Bacteriological Techniques; Brucella melitensis; Brucellosis; Carbon Dioxide; Colony Count, Microbial; Culture Media; Evaluation Studies as Topic; Humans; Hydrogen-Ion Concentration; Polyanetholesulfonate; Pyruvates; Pyruvic Acid | 1993 |
The inhibitory action of buformin, a biguanide on gluconeogenesis from alanine and its transport system in rat livers.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Animals; Biological Transport, Active; Buformin; Cell Separation; Diabetes Mellitus, Experimental; Glucagon; Gluconeogenesis; Hydroxybutyrates; Lactates; Lactic Acid; Liver; Male; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Tolbutamide | 1993 |
Site-directed alteration of three active-site residues of a pyruvoyl-dependent histidine decarboxylase.
Topics: Alanine; Allosteric Regulation; Asparagine; Binding Sites; Histidine; Histidine Decarboxylase; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Lactobacillus; Mutagenesis, Site-Directed; Phenylalanine; Pyruvates; Pyruvic Acid; Recombinant Proteins; Tyrosine; Valine | 1993 |
Exogenous glutamate concentration regulates the metabolic fate of glutamate in astrocytes.
Topics: Alanine; Animals; Aspartic Acid; Astrocytes; Biological Transport; Cell Compartmentation; Cells, Cultured; Citric Acid Cycle; Culture Media, Conditioned; Extracellular Space; Glutamic Acid; Glutamine; Lactates; Magnetic Resonance Spectroscopy; Mice; Pyruvates; Pyruvic Acid; Rats | 1996 |
Experimental streptozotocin-reduced diabetes and intestinal glucose metabolism in the rat, in vivo and in vitro.
Topics: Alanine; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Glycolysis; In Vitro Techniques; Intestine, Small; Lactates; Lactic Acid; Male; Osmolar Concentration; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Reference Values | 1995 |
Alanine as an end product during fermentation of monosaccharides by Clostridium strain P2.
Topics: Alanine; Anaerobiosis; Clostridium; Fermentation; Hexoses; Hot Temperature; Models, Chemical; Pyruvic Acid | 1995 |
Conversion of L-lactate oxidase to a long chain alpha-hydroxyacid oxidase by site-directed mutagenesis of alanine 95 to glycine.
Topics: Alanine; Alcohol Oxidoreductases; Animals; Enzyme Stability; Glycine; Kinetics; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Pyruvic Acid; Rats; Substrate Specificity | 1996 |
Metabolism of [U-13C5] glutamine in cultured astrocytes studied by NMR spectroscopy: first evidence of astrocytic pyruvate recycling.
Topics: Alanine; Animals; Animals, Newborn; Astrocytes; Carbon Isotopes; Cells, Cultured; Cerebral Cortex; Gas Chromatography-Mass Spectrometry; Glutamine; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred Strains; Pyruvic Acid | 1996 |
Linkage of aerobic glycolysis to sodium-potassium transport in rat skeletal muscle. Implications for increased muscle lactate production in sepsis.
Topics: Aerobiosis; Alanine; Amino Acids; Animals; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Glycolysis; Hindlimb; Hydrogen-Ion Concentration; Lactic Acid; Lipopolysaccharides; Male; Monensin; Muscle, Skeletal; Ouabain; Potassium; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Shock, Septic; Sodium; Sodium-Potassium-Exchanging ATPase | 1996 |
Construction of L-lysine-overproducing strains of Brevibacterium lactofermentum by targeted disruption of the hom and thrB genes.
Topics: Alanine; Blotting, Southern; Brevibacterium; Cloning, Molecular; Conjugation, Genetic; DNA, Bacterial; Gene Expression Regulation, Bacterial; Homoserine Dehydrogenase; Lysine; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Pyruvic Acid | 1996 |
Dichloroacetate inhibits glutamine oxidation by decreasing pyruvate availability for transamination.
Topics: Alanine; Animals; Cell Line; Cell Survival; Dichloroacetic Acid; Dose-Response Relationship, Drug; Glutamine; Hybridomas; Oxidation-Reduction; Pyruvic Acid; Time Factors | 1997 |
Hepatic glucose production from L-alanine is absent in perfused liver of diabetic rats.
Topics: Alanine; Alloxan; Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Gluconeogenesis; Glucose; Glycerol; Infusions, Intravenous; Lactic Acid; Liver; Male; NAD; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Software; Sorbitol; Streptozocin | 1997 |
The purpose of glycolysis.
Topics: Alanine; Animals; Brain; Cerebrovascular Circulation; Cytosol; Glycolysis; Humans; Lactic Acid; Neurons; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid | 1997 |
Pyridoxamine-amino acid chimeras in semisynthetic aminotransferase mimics.
Topics: Alanine; Amino Acids; Catalysis; Models, Molecular; Pyridoxamine; Pyruvic Acid; Ribonucleases; Stereoisomerism; Transaminases | 1997 |
Action of polyamine aminotransferase on norspermidine.
Topics: Acrolein; Alanine; Allylamine; Arthrobacter; Biogenic Polyamines; Diamines; Kinetics; NAD; Pyruvic Acid; Spermidine; Transaminases | 1997 |
Substrate inhibition of D-amino acid transaminase and protection by salts and by reduced nicotinamide adenine dinucleotide: isolation and initial characterization of a pyridoxo intermediate related to inactivation.
Topics: Alanine; Catalysis; Chromatography, High Pressure Liquid; D-Alanine Transaminase; Enzyme Inhibitors; NAD; Pyridoxal Phosphate; Pyridoxamine; Pyruvic Acid; Salts; Serine; Transaminases | 1998 |
Metabolism of [3-(13)C]-pyruvate by cysticerci of Taenia crassiceps.
Topics: Acetates; Alanine; Animals; Citric Acid; Citric Acid Cycle; Cysticercus; Cytosol; Lactic Acid; Magnetic Resonance Spectroscopy; Malate Dehydrogenase; Mitochondria; Pyruvic Acid; Succinic Acid | 1998 |
Analysis of the structure and substrate binding of Phormidium lapideum alanine dehydrogenase.
Topics: Alanine; Alanine Dehydrogenase; Amino Acid Oxidoreductases; Amino Acid Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; Cyanobacteria; Models, Molecular; Molecular Sequence Data; NAD; Protein Conformation; Pyruvic Acid | 1998 |
Restoration of rat liver L-threonine dehydratase activity by pyridoxamine 5'-phosphate: the half-transaminating activity of L-threonine dehydratase and its regulatory role.
Topics: Acetoacetates; Alanine; Animals; Apoenzymes; Enzyme Reactivators; Liver; Male; Pyridoxal Phosphate; Pyridoxamine; Pyruvic Acid; Rats; Rats, Wistar; Threonine Dehydratase | 1998 |
Excitatory amino acid synthesis in hypoxic brain slices: does alanine act as a substrate for glutamate production in hypoxia?
Topics: Alanine; Animals; Brain; Carbon; Excitatory Amino Acids; Glutamic Acid; Glutamine; Guinea Pigs; Hypoxia; In Vitro Techniques; Intracellular Membranes; Osmolar Concentration; Perfusion; Pyruvic Acid; Reference Values; Substrate Specificity | 1998 |
Metabolic effects of oxalate in the perfused rat liver.
Topics: Alanine; Animals; Ascorbic Acid; Gluconeogenesis; Glycolysis; In Vitro Techniques; Kinetics; Lactic Acid; Liver; Liver Glycogen; Male; Oxalic Acid; Oxygen Consumption; Perfusion; Pyruvic Acid; Rats; Rats, Wistar | 1998 |
Kinetic modeling of omega-transamination for enzymatic kinetic resolution of alpha-methylbenzylamine.
Topics: Acetophenones; Alanine; Bacillus thuringiensis; Buffers; Enzyme Inhibitors; Kinetics; Models, Chemical; Phenethylamines; Pyruvic Acid; Stereoisomerism; Transaminases; Water | 1998 |
Lipoic acid acutely induces hypoglycemia in fasting nondiabetic and diabetic rats.
Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; Fasting; Fatty Acids, Nonesterified; Glucagon; Gluconeogenesis; Hypoglycemia; Liver; Male; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Thioctic Acid | 1999 |
Carbon-13 nuclear magnetic resonance study of metabolism of propionate by Escherichia coli.
Topics: Acyl Coenzyme A; Alanine; Carbon Isotopes; Cell Wall; Citrates; Citric Acid; Citric Acid Cycle; Escherichia coli; Formates; Gluconeogenesis; Glutamic Acid; Glycine; Magnetic Resonance Spectroscopy; Methylmalonic Acid; Oxaloacetic Acid; Propionates; Protons; Putrescine; Pyruvic Acid; Succinic Acid; Trehalose | 1999 |
Pyruvate metabolism by Anaplasma marginale in cell-free culture.
Topics: Alanine; Anaplasma; Cell-Free System; Pyruvic Acid | 1999 |
Plasma metabolites after a lipid load in infants with congenital heart disease.
Topics: Alanine; Blood Glucose; Chromatography, Gas; Chromatography, Thin Layer; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Fluorometry; Glycerol; Growth Disorders; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Ketones; Lactates; Linoleic Acid; Lipolysis; Pyruvic Acid; Severity of Illness Index; Triglycerides | 1999 |
Asymmetric synthesis of chiral amines with omega-transaminase.
Topics: Alanine; Amines; Enzyme Inhibitors; Hydrogen-Ion Concentration; Ketones; Kinetics; L-Lactate Dehydrogenase; Molecular Conformation; Pyruvic Acid; Transaminases; Vibrio | 1999 |
Alanine or pyruvate is required for the development of myotubes from myoblasts and cortisol satisfies this requirement.
Topics: Alanine; Animals; Aspartic Acid; Chick Embryo; Hydrocortisone; Ketoglutaric Acids; Muscle, Skeletal; Pyruvic Acid; Rats | 1999 |
Gluconeogenesis in the liver of arthritic rats.
Topics: Alanine; Animals; Arthritis, Experimental; Gluconeogenesis; Glucose; Glutamine; Glycerol; Lactic Acid; Liver; Male; Oxygen; Pyruvic Acid; Rats; Rats, Wistar; Xylitol | 1999 |
Mechanisms of increased gluconeogenesis from alanine in rat isolated hepatocytes after endurance training.
Topics: Alanine; Animals; Biological Transport; Cell Separation; Gluconeogenesis; Liver; Male; NAD; Perfusion; Phosphoenolpyruvate; Physical Conditioning, Animal; Physical Endurance; Pyruvic Acid; Rats; Rats, Wistar; Reference Values | 2000 |
Hyperammonemia induced by administration of glucose and insulin after hepatopancreatectomy in rats.
Topics: Alanine; Ammonia; Animals; Energy Metabolism; Glucose; Glutamine; Glycolysis; Hepatectomy; Insulin; Lactic Acid; Male; Pancreatectomy; Pyruvic Acid; Rats; Rats, Wistar | 1999 |
Lysine 199 is the general acid in the NAD-malic enzyme reaction.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Ascaris suum; Catalysis; Conserved Sequence; Hydrogen-Ion Concentration; Kinetics; Lysine; Malate Dehydrogenase; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Oxaloacetic Acid; Pyruvic Acid; Solvents; Tritium | 2000 |
Stereochemistry of the transamination reaction catalyzed by aminodeoxychorismate lyase from Escherichia coli: close relationship between fold type and stereochemistry.
Topics: Alanine; Apoenzymes; Catalysis; Escherichia coli; Evolution, Molecular; Hydrogen; Kinetics; Molecular Conformation; Oxo-Acid-Lyases; Protein Folding; Pyridoxal Phosphate; Pyridoxamine; Pyruvic Acid; Recombinant Proteins; Spectrophotometry; Transaminases; Tryptophan Synthase; Tryptophanase | 2000 |
Low-dose IGF-I has no selective advantage over insulin in regulating glucose metabolism in hyperglycemic depancreatized dogs.
Topics: 3-Hydroxybutyric Acid; Alanine; Analysis of Variance; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Dogs; Drug Administration Schedule; Fatty Acids, Nonesterified; Glucose Clamp Technique; Glycerol; Insulin; Insulin-Like Growth Factor I; Lactic Acid; Male; Pancreatectomy; Pyruvic Acid | 2001 |
Rapid kinetic and isotopic studies on dialkylglycine decarboxylase.
Topics: Alanine; Aminoisobutyric Acids; Carbon Isotopes; Carboxy-Lyases; Decarboxylation; Deuterium; Enzyme Activation; Isoenzymes; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Protons; Pyridoxal Phosphate; Pyruvic Acid; Transaminases | 2001 |
Parasitism enhances the induction of glucogenesis by the insect, Manduca sexta L.
Topics: Alanine; Animals; Carbon Isotopes; Diet; Gluconeogenesis; Hemolymph; Hymenoptera; Magnetic Resonance Spectroscopy; Manduca; Pyruvate Kinase; Pyruvic Acid; Trehalose | 2001 |
Spatial heterogeneity of energy turnover in the heart.
Topics: Alanine; Animals; Aspartic Acid; Carbon Isotopes; Citric Acid; Citric Acid Cycle; Coronary Circulation; Dogs; Energy Metabolism; Glutamic Acid; Ketoglutaric Acids; Lactic Acid; Magnetic Resonance Spectroscopy; Malates; Models, Biological; Myocardium; Oxaloacetic Acid; Oxygen Consumption; Pyruvic Acid | 2001 |
13C isotopomer analysis of glucose and alanine metabolism reveals cytosolic pyruvate compartmentation as part of energy metabolism in astrocytes.
Topics: Alanine; Animals; Animals, Newborn; Astrocytes; Brain; Brain Chemistry; Carbon Radioisotopes; Cell Compartmentation; Cell Extracts; Cells, Cultured; Culture Media; Cytosol; Energy Metabolism; Enzymes; Glucose; Glutamic Acid; Glutamine; Hydrogen; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Rats; Rats, Wistar | 2001 |
Development and evaluation of a boronate inhibitor of gamma-glutamyl transpeptidase.
Topics: Alanine; Alanine Transaminase; Aminobutyrates; Animals; Aspartate Aminotransferases; Binding Sites; Boron Compounds; Carbon Isotopes; Cell Division; Cell Line; Culture Media; Cysteine; gamma-Glutamyltransferase; Glutamine; Hydrogen-Ion Concentration; Kinetics; Liver; Magnetic Resonance Spectroscopy; Oxaloacetic Acid; Protons; Pyruvic Acid; Rats | 2001 |
Rat liver responsiveness to gluconeogenic substrates during insulin-induced hypoglycemia.
Topics: Alanine; Animals; Blood Glucose; Cryoprotective Agents; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hypoglycemia; Hypoglycemic Agents; Insulin; Lactic Acid; Liver; Male; Pyruvic Acid; Rats; Rats, Wistar; Urea | 2001 |
Partial amino acid catabolism leading to the formation of alanine in Periophthalmodon schlosseri (mudskipper): a strategy that facilitates the use of amino acids as an energy source during locomotory activity on land.
Topics: Adenosine Triphosphate; Air; Alanine; Amino Acids; Animals; Citric Acid Cycle; Energy Metabolism; Glycogen; Lactic Acid; Liver; Malate Dehydrogenase; Malates; Motor Activity; Muscles; Oxidation-Reduction; Perciformes; Photoperiod; Physical Exertion; Pyruvic Acid | 2001 |
Catalytic acid-base groups in yeast pyruvate decarboxylase. 2. Insights into the specific roles of D28 and E477 from the rates and stereospecificity of formation of carboligase side products.
Topics: Acetaldehyde; Acetoin; Acetolactate Synthase; Alanine; Aspartic Acid; Catalytic Domain; Circular Dichroism; Decarboxylation; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Kinetics; Lactates; Pyruvate Decarboxylase; Pyruvic Acid; Recombinant Proteins; Saccharomyces cerevisiae; Stereoisomerism; Substrate Specificity | 2001 |
Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity.
Topics: Alanine; Allosteric Regulation; Aniline Compounds; Aspartic Acid; Benzimidazoles; beta-Alanine; Catalysis; Deuterium; Enzyme Activation; Hydroxylamines; Indoles; Kinetics; Multienzyme Complexes; Mutagenesis, Site-Directed; Pyruvic Acid; Salmonella typhimurium; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity; Titrimetry; Tryptophan Synthase | 2001 |
Effects of acute exercise on the gluconeogenic capacity of periportal and perivenous hepatocytes.
Topics: Alanine; Animals; Energy Metabolism; Gluconeogenesis; Glucose; Hepatocytes; Lactose; Liver; Male; Physical Exertion; Portal Vein; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2001 |
The synthesis of glutamic acid in the absence of enzymes: implications for biogenesis.
Topics: Alanine; Ammonia; Ammonium Chloride; Catalysis; Evolution, Chemical; Formates; Glutamic Acid; Glycine; Glyoxylates; Hydrogen-Ion Concentration; Keto Acids; Ketoglutaric Acids; Origin of Life; Pyruvic Acid; Reducing Agents | 1995 |
Prebiotic transamination.
Topics: Alanine; Amino Acids; Evolution, Chemical; Glutamic Acid; Hydrogen-Ion Concentration; Keto Acids; Ketoglutaric Acids; Phenylalanine; Phenylpyruvic Acids; Pyruvic Acid; Transaminases | 1997 |
Is ischemia involved in the pathogenesis of murine cerebral malaria?
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Animals; Brain; Brain Ischemia; Chromatography, High Pressure Liquid; Female; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Malaria, Cerebral; Mice; Mice, Inbred CBA; NAD; Osmolar Concentration; Pyruvic Acid | 2001 |
Encapsulation of PEG-urease/PEG-AlaDH enzyme system in erythrocyte.
Topics: Alanine; Alanine Dehydrogenase; Amino Acid Oxidoreductases; Ammonia; Diabetes Mellitus; Drug Compounding; Drug Delivery Systems; Enzymes, Immobilized; Erythrocytes; Hematologic Tests; Humans; Kinetics; Polyethylene Glycols; Pyruvic Acid; Urease | 2001 |
Fetal hepatic and umbilical uptakes of glucogenic substrates during a glucagon-somatostatin infusion.
Topics: Alanine; Animals; Arginine; Blood Glucose; Female; Fetal Blood; Gestational Age; Glucagon; Gluconeogenesis; Glucose; Glutamine; Lactic Acid; Liver; Ornithine; Oxygen Consumption; Placenta; Pregnancy; Pyruvic Acid; Sheep; Somatostatin; Umbilical Veins | 2002 |
Mechanisms of the protective effect of L-alanine to D-galactosamine-induced hepatocellular injury: comparative studies of L-alanine and pyruvate.
Topics: Alanine; Albumins; Aminoisobutyric Acids; Aminooxyacetic Acid; Animals; Cells, Cultured; Galactosamine; Hepatocytes; L-Lactate Dehydrogenase; Liver Failure; Male; Oligomycins; Pyruvic Acid; Quinolinic Acid; Rats; Rats, Sprague-Dawley | 2002 |
Effect of diet supplementation with l-carnitine on hepatic catabolism of l-alanine in rats.
Topics: Alanine; Animals; Carnitine; Dietary Supplements; Glucose; Lactic Acid; Liver; Male; Pyruvic Acid; Rats; Rats, Wistar; Urea | 2002 |
Amino acid kinetics during the anhepatic phase of liver transplantation.
Topics: Alanine; Amino Acids; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Deuterium; Electrolytes; Fatty Acids, Nonesterified; Gluconeogenesis; Glutamine; Glycerol; Hematocrit; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Leucine; Liver; Liver Transplantation; Metabolic Clearance Rate; Middle Aged; Nitrogen; Oxygen; Pyruvic Acid | 2002 |
A nuclear magnetic resonance-based demonstration of substantial oxidative L-alanine metabolism and L-alanine-enhanced glucose metabolism in a clonal pancreatic beta-cell line: metabolism of L-alanine is important to the regulation of insulin secretion.
Topics: Adenosine Triphosphate; Alanine; Carbon Isotopes; Cell Line; Citric Acid Cycle; Clone Cells; Glucose; Glutamic Acid; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Oligomycins; Oxidation-Reduction; Oxidative Phosphorylation; Pyruvic Acid | 2002 |
Hepatic gluconeogenic capacity from various precursors in young versus old rats.
Topics: Aging; Alanine; Animals; Body Weight; Cell Separation; Cell Survival; Dihydroxyacetone; Fasting; Fructose; Gluconeogenesis; Glucose; Glutamine; Glycerol; Glycogen; Hepatocytes; Lactic Acid; Liver; Male; Oxaloacetates; Pyruvic Acid; Rats; Rats, Inbred F344 | 2002 |
Purinergic regulation of glucose and glutamine synthesis in isolated rabbit kidney-cortex tubules.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Ammonium Chloride; Animals; Aspartic Acid; Calcium Signaling; Cyclic AMP; Dose-Response Relationship, Drug; Fructose-Bisphosphatase; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hypoxanthine; In Vitro Techniques; Inosine; Kidney Tubules; Ligands; Male; Phosphorylation; Pyruvic Acid; Rabbits; Signal Transduction | 2002 |
Intracellular pyruvate flux in the methane-producing archaeon Methanococcus maripaludis.
Topics: Alanine; Carbon Radioisotopes; Isoleucine; Leucine; Methane; Methanococcus; Oxidoreductases; Pyruvic Acid | 2002 |
First-principles molecular dynamics investigation of the D-amino acid oxidative half-reaction catalyzed by the flavoenzyme D-amino acid oxidase.
Topics: Alanine; Animals; Binding Sites; Catalysis; D-Amino-Acid Oxidase; Electron Transport; Energy Transfer; Enzyme Stability; Flavins; Imino Acids; Kidney; Kinetics; Models, Chemical; Oxidation-Reduction; Protein Structure, Secondary; Protons; Pyruvic Acid; Rhodotorula; Swine; Thermodynamics | 2002 |
Effects of endurance training on the gluconeogenic capacity of periportal and perivenous hepatocytes.
Topics: Alanine; Animals; Cell Separation; Female; Gluconeogenesis; Glutamate-Ammonia Ligase; Hepatic Veins; Hepatocytes; Kinetics; Lactic Acid; Physical Conditioning, Animal; Physical Endurance; Portal Vein; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2003 |
Determination of D- and L-alanine concentrations using a pyruvic acid sensor.
Topics: Alanine; Animals; Biosensing Techniques; Bivalvia; Electrochemistry; Environmental Pollutants; Equipment Design; Equipment Failure; Hydrogen; Isomerism; Mollusca; Oxidation-Reduction; Oxygen; Pyruvate Oxidase; Pyruvic Acid; Reproducibility of Results; Sensitivity and Specificity; Temperature | 2003 |
Differential modulation of glucose, lactate, and pyruvate oxidation by insulin and dichloroacetate in the rat heart.
Topics: Acetyl Coenzyme A; Alanine; Animals; Buffers; Citric Acid Cycle; Dichloroacetic Acid; Energy Metabolism; Glucose; Heart; Heart Function Tests; Heart Rate; Hypoglycemic Agents; In Vitro Techniques; Insulin; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardium; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Ventricular Function, Left | 2003 |
Enhanced energy metabolism during cold hypoxic organ preservation: studies on rat liver after pyruvate supplementation.
Topics: Adenosine; Adenosine Triphosphate; Alanine; Allopurinol; Animals; Cryopreservation; Dose-Response Relationship, Drug; Drug Combinations; Energy Metabolism; Glutathione; Insulin; Lactic Acid; Liver; Male; Organ Preservation Solutions; Osmolar Concentration; Pyruvic Acid; Raffinose; Rats; Rats, Sprague-Dawley; Succinic Acid | 2003 |
Exercise and recovery metabolism in the Pacific spiny dogfish (Squalus acanthias).
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Alanine; Ammonia; Analysis of Variance; Animals; Basal Metabolism; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Coenzyme A; Creatine; Dogfish; Electric Stimulation; Energy Metabolism; Female; Glucose; Glycogen; Hydrogen-Ion Concentration; Lactic Acid; Male; Muscle Fatigue; Muscle Fibers, Fast-Twitch; Oxygen; Partial Pressure; Perfusion; Phosphocreatine; Pyruvate Dehydrogenase Complex; Pyruvic Acid | 2003 |
L-Serine, D- and L-proline and alanine as respiratory substrates of Helicobacter pylori: correlation between in vitro and in vivo amino acid levels.
Topics: 2,6-Dichloroindophenol; Alanine; Amino Acids; Ammonia; Gastric Juice; Helicobacter pylori; Humans; In Vitro Techniques; Oxidation-Reduction; Oxygen Consumption; Proline; Pyruvic Acid; Serine; Stereoisomerism | 2003 |
Presence of D-alanine in an endopeptidase from Streptococcus pyogenes.
Topics: Alanine; Bacterial Proteins; Carbon Radioisotopes; Catalase; D-Amino-Acid Oxidase; Endopeptidases; Pyruvic Acid; Stereoisomerism; Streptococcus pyogenes | 2003 |
Observations of the effect of amino acids on the growth initiation of Rhizobium meliloti, with special reference to the synthesis of alanine from pyruvate and ammonium ions.
Topics: Alanine; Amino Acids; Ammonia; Ammonium Compounds; Ions; Pyruvates; Pyruvic Acid; Rhizobium; Sinorhizobium meliloti | 1957 |
Potentiation of renoprival hypertension by alanine, pyruvate and lactate.
Topics: Alanine; Humans; Hypertension; Hypertension, Renal; Lactates; Lactic Acid; Nephrectomy; Pyruvates; Pyruvic Acid | 1957 |
Accumulation of alpha-alanine and of pyruvate in diphtherial culture filtrate and its relation to iron deficiency of medium.
Topics: Alanine; Biochemical Phenomena; Corynebacterium diphtheriae; Iron; Pyruvates; Pyruvic Acid | 1958 |
[Synthesis of alanine from pyruvic acid and ammonia by purified enzymatic preparations from rat liver mitochondria].
Topics: Alanine; Ammonia; Animals; Biochemical Phenomena; Enzymes; Liver; Mitochondria; Mitochondria, Liver; Pyruvates; Pyruvic Acid; Rats | 1958 |
An improved method for determining pyruvic acid levels in tissues. Estimation of the aspartic-ketoglutaric and alanine-ketoglutaric transaminases.
Topics: Alanine; Alanine Transaminase; Pyruvates; Pyruvic Acid; Transaminases | 1961 |
Contributions to silkworm biochemistry. VIII. Conversion of pyruvate into alanine, glycine and serine of silkfibroin.
Topics: Alanine; Animals; Bombyx; Fabaceae; Glycine; Proteins; Pyruvates; Pyruvic Acid; Serine | 1959 |
[Oxidoreduction potentials of the alanine-ammonium pyruvate and valine-ammonium alpha-ketoisovalerate systems. New determination].
Topics: Alanine; Ammonium Compounds; Fatty Acids; Hemiterpenes; Keto Acids; Pyruvates; Pyruvic Acid; Valine | 1962 |
Pyruvate and alanine metabolism in carp liver mitochondria.
Topics: Alanine; Animals; Carps; Fishes; Liver; Mitochondria; Mitochondria, Liver; Pyruvates; Pyruvic Acid | 1962 |
EFFECT OF INSULIN IN VITRO ON INCORPORATION OF 14-D FROM PYRUVATE INTO THE PROTEIN OF ISOLATED RAT DIAPHRAGM IN THE PRESENCE OF (12-CALANINE,(12-C)ASPARTIC ACID AND(12-C)GLUTAMIC ACID.
Topics: Alanine; Aspartic Acid; Biological Transport; Carbon Isotopes; Diaphragm; Glutamates; Glutamic Acid; In Vitro Techniques; Insulin; Muscles; Pharmacology; Proteins; Pyruvates; Pyruvic Acid; Rats; Research | 1964 |
INHIBITORY ACTION OF PYRUVATE ON D-AMINOACID OXIDASE.
Topics: Alanine; Amino Acid Oxidoreductases; D-Amino-Acid Oxidase; Enzyme Inhibitors; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Fluorescence; Light; Manometry; Oxidoreductases; Polarography; Pyruvates; Pyruvic Acid; Research; Riboflavin | 1964 |
CONTROL OF GLUTAMATE METABOLISM. THE EFFECT OF PYRUVATE.
Topics: Alanine; Aspartate Aminotransferases; Aspartic Acid; Brain; Carbon Isotopes; Glutamates; Glutamic Acid; Keto Acids; Liver; Lyases; Mitochondria; Oxaloacetates; Pyruvates; Pyruvic Acid; Radiometry; Research | 1965 |
RATE OF UTILIZATION OF GLUCOSE AND 'COMPARTMENTATION' OF ALPHA-OXOGLUTARATE AND GLUTAMATE IN RAT BRAIN.
Topics: Alanine; Amino Acids; Blood; Blood Glucose; Brain; Brain Chemistry; Chemistry Techniques, Analytical; Glucose; Glutamates; Glutamic Acid; Glycolysis; Ketoglutaric Acids; Kinetics; Lactates; Lactic Acid; Liver; Pyruvates; Pyruvic Acid; Rats; Research | 1965 |
Alpha-keto acids in vitamin-free casein hydrolyzates (acid).
Topics: Alanine; Amino Acids; Aminobutyrates; Caseins; Glutamic Acid; Keto Acids; Pyruvic Acid; Vitamins | 1959 |
Modulation of the positive inotropic effect of pyruvate by energetic substrate availability.
Topics: Alanine; Animals; Antihypertensive Agents; Biological Availability; Caprylates; Cardiotonic Agents; Coumaric Acids; Dose-Response Relationship, Drug; Humans; Mitochondria, Heart; Models, Animal; Models, Cardiovascular; Myocardial Contraction; Myocardium; Papillary Muscles; Pyruvic Acid; Rabbits | 2003 |
Retinal function loss after monocarboxylate transport inhibition.
Topics: Alanine; Animals; Coumaric Acids; Dark Adaptation; Electroretinography; Enzyme Inhibitors; Glutamine; Interneurons; Ketoglutaric Acids; Monocarboxylic Acid Transporters; Pyruvic Acid; Rats; Rats, Long-Evans; Retina; Succinic Acid; Vision, Ocular | 2004 |
Role of active-site residues Thr81, Ser82, Thr85, Gln157, and Tyr158 in yeast cystathionine beta-synthase catalysis and reaction specificity.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Catalysis; Chromatography, Affinity; Cystathionine beta-Synthase; Glutamine; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Nickel; Phenylalanine; Pyruvic Acid; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity; Threonine; Tyrosine | 2004 |
Reaction of Pseudomonas fluorescens kynureninase with beta-benzoyl-L-alanine: detection of a new reaction intermediate and a change in rate-determining step.
Topics: Alanine; Bacterial Proteins; Benzoates; Hydrolases; Kinetics; Kynurenine; Protons; Pseudomonas fluorescens; Pyruvic Acid; Recombinant Proteins; Spectrophotometry; Substrate Specificity | 2004 |
Ammonium exposure and pyruvate affect the amino acid metabolism of bovine blastocysts in vitro.
Topics: Alanine; Amino Acids; Animals; Arginine; Blastocyst; Cattle; Cells, Cultured; Fertilization in Vitro; Glutamate Dehydrogenase; Glutamic Acid; Pyruvic Acid; Quaternary Ammonium Compounds; Urea | 2004 |
Aerobic production of alanine by Escherichia coli aceF ldhA mutants expressing the Bacillus sphaericus alaD gene.
Topics: Aerobiosis; Alanine; Bacillus; Escherichia coli; Fermentation; Gene Expression Regulation, Bacterial; Glucose; L-Lactate Dehydrogenase; Oxygen Consumption; Pyruvic Acid; Recombinant Proteins | 2004 |
Metabolic properties of Eubacterium pyruvativorans, a ruminal 'hyper-ammonia-producing' anaerobe with metabolic properties analogous to those of Clostridium kluyveri.
Topics: Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; Caseins; Clostridium; Crotonates; Energy Metabolism; Eubacterium; Fatty Acids, Volatile; Fermentation; Glycine; Lactic Acid; Leucine; Peptides; Proline; Pyruvic Acid; Rumen; Serine; Threonine | 2004 |
Metabolic effects of propofol in the isolated perfused rat liver.
Topics: Alanine; Anesthetics, Intravenous; Animals; Energy Metabolism; Gluconeogenesis; Glycerol; Glycolysis; In Vitro Techniques; Infusions, Intravenous; Lactic Acid; Liver; Male; Mitochondria, Liver; Oxygen; Phosphorylation; Propofol; Pyruvic Acid; Rats; Rats, Wistar; Time Factors | 2004 |
Relative carnitine deficiency in autism.
Topics: Adolescent; Alanine; Autistic Disorder; Carnitine; Child; Child, Preschool; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Hyperammonemia; Lactic Acid; Male; Pyruvic Acid; Retrospective Studies | 2004 |
Contribution of L-3,4-dihydroxyphenylalanine metabolism to the inhibition of gluconeogenesis in rabbit kidney-cortex tubules.
Topics: Alanine; Animals; Aspartic Acid; Caprylates; Depression, Chemical; Dihydroxyacetone; Dopamine; Gluconeogenesis; Glutathione; Glutathione Disulfide; Glycerol; Hydrogen Peroxide; In Vitro Techniques; Kidney Tubules; Levodopa; Male; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvic Acid; Rabbits; Selegiline; Tyramine | 2005 |
Purification and biochemical characterization of a pyruvate-specific class II aldolase, HpaI.
Topics: Alanine; Aldehyde-Lyases; Animals; Arginine; Binding Sites; Cations, Divalent; Escherichia coli Proteins; Kinetics; Malate Dehydrogenase; Metals, Heavy; Phenylacetates; Pyruvic Acid; Rabbits; Spectrometry, Fluorescence; Substrate Specificity | 2005 |
Functional analysis of all aminotransferase proteins inferred from the genome sequence of Corynebacterium glutamicum.
Topics: Alanine; Aspartic Acid; Bacterial Proteins; Butyrates; Carbon-Sulfur Lyases; Corynebacterium glutamicum; Gene Deletion; Glutamic Acid; Hemiterpenes; Keto Acids; Phenylpyruvic Acids; Pyruvic Acid; Substrate Specificity; Transaminases | 2005 |
Fast metabolic imaging of systems with sparse spectra: application for hyperpolarized 13C imaging.
Topics: Alanine; Artifacts; Carbon Isotopes; Image Processing, Computer-Assisted; Lactates; Magnetic Resonance Imaging; Phantoms, Imaging; Pyruvic Acid; Signal Processing, Computer-Assisted | 2006 |
Low doses of tumour necrosis factor alpha and interleukin 1beta diminish hepatic gluconeogenesis from alanine in vivo.
Topics: Alanine; Ammonia; Animals; Dose-Response Relationship, Drug; Drug Combinations; Gluconeogenesis; Glucose; Infusions, Intravenous; Interleukin-1beta; Lactic Acid; Liver; Male; Oxygen Consumption; Perfusion; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Time Factors; Tumor Necrosis Factor-alpha; Urea | 2006 |
Desulfotomaculum thermosubterraneum sp. nov., a thermophilic sulfate-reducer isolated from an underground mine located in a geothermally active area.
Topics: Alanine; Alcohols; Bacterial Typing Techniques; Base Composition; Carbohydrate Metabolism; Carboxylic Acids; Desulfotomaculum; DNA, Bacterial; DNA, Ribosomal; Fatty Acids; Genes, rRNA; Growth Inhibitors; Hydrogen; Hydrogen-Ion Concentration; Japan; Lactic Acid; Mining; Molecular Sequence Data; Movement; Nucleic Acid Hybridization; Phylogeny; Pyruvic Acid; Quinones; RNA, Bacterial; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Sodium Chloride; Soil Microbiology; Sulfates; Sulfites; Sulfur; Temperature | 2006 |
Metabolic imaging by hyperpolarized 13C magnetic resonance imaging for in vivo tumor diagnosis.
Topics: Alanine; Animals; Carbon Isotopes; Lactic Acid; Magnetic Resonance Imaging; Male; Neoplasms, Experimental; Pyruvic Acid; Rats | 2006 |
L-valine production with pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum.
Topics: Alanine; Corynebacterium glutamicum; Fermentation; Isoleucine; Lysine; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Valine | 2007 |
Formation of 5-hydroxymethyl-2-furfural (HMF) and 5-hydroxymethyl-2-furoic acid during roasting of coffee.
Topics: Alanine; Chlorogenic Acid; Coffea; Food Handling; Furaldehyde; Furans; Glyceraldehyde; Hot Temperature; Pyruvic Acid; Seeds; Sucrose; Time Factors | 2007 |
Optimization of fast spiral chemical shift imaging using least squares reconstruction: application for hyperpolarized (13)C metabolic imaging.
Topics: Alanine; Algorithms; Artifacts; Carbon Isotopes; Image Processing, Computer-Assisted; Lactates; Least-Squares Analysis; Magnetic Resonance Imaging; Phantoms, Imaging; Pyruvic Acid; Signal Processing, Computer-Assisted | 2007 |
Flexibility of the hepatic zonation of carbon and nitrogen fluxes linked to lactate and pyruvate transformations in the presence of ammonia.
Topics: Alanine; Ammonia; Animals; Carbon; Glutamic Acid; In Vitro Techniques; Lactates; Liver; Male; Microcirculation; Nitrogen; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Urea | 2007 |
Formation of diacetyl and acetoin by Lactococcus lactis via aspartate catabolism.
Topics: Acetoin; Alanine; Aspartic Acid; Cells, Cultured; Cheese; Diacetyl; Food Microbiology; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Ketoglutaric Acids; Lactates; Lactococcus lactis; Metabolism; Pyruvic Acid | 2008 |
Least-squares chemical shift separation for (13)C metabolic imaging.
Topics: Alanine; Algorithms; Carbon Isotopes; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Lactic Acid; Least-Squares Analysis; Magnetic Resonance Imaging; Models, Biological; Models, Chemical; Models, Statistical; Phantoms, Imaging; Pyruvic Acid | 2007 |
Feasibility of using hyperpolarized [1-13C]lactate as a substrate for in vivo metabolic 13C MRSI studies.
Topics: Alanine; Animals; Carbon Isotopes; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2008 |
The role of a conserved histidine residue in a pyruvate-specific Class II aldolase.
Topics: Alanine; Aldehyde-Lyases; Amino Acid Sequence; Amino Acid Substitution; Conserved Sequence; Escherichia coli Proteins; Evolution, Molecular; Glutamine; Histidine; Mutation; Protein Conformation; Pyruvic Acid | 2008 |
Effects of monocrotaline on energy metabolism in the rat liver.
Topics: Alanine; Animals; Carcinogens; Cytochrome P-450 Enzyme System; Data Interpretation, Statistical; Energy Metabolism; Gluconeogenesis; Glycogen; Glycolysis; Liver; Liver Circulation; Male; Monocrotaline; Oxygen Consumption; Phenobarbital; Pyruvic Acid; Rats; Rats, Wistar; Urea | 2008 |
Metabolic function of Corynebacterium glutamicum aminotransferases AlaT and AvtA and impact on L-valine production.
Topics: Alanine; Corynebacterium glutamicum; Cytosol; Gene Deletion; Kinetics; Pyruvic Acid; Substrate Specificity; Transaminases; Valine | 2008 |
Evidence that L-glutamine is better than L-alanine as gluconeogenic substrate in perfused liver of weaned fasted rats submitted to short-term insulin-induced hypoglycaemia.
Topics: Alanine; Animals; Fasting; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Insulin; Lactic Acid; Liver; Male; Perfusion; Pyruvic Acid; Rats; Time Factors; Weaning | 2009 |
Glycerol: an unexpected major metabolite of energy metabolism by the human malaria parasite.
Topics: Alanine; Anaerobiosis; Animals; Energy Metabolism; Glucose; Glycerol; Humans; Lactic Acid; NAD; Oxidation-Reduction; Plasmodium falciparum; Pyruvic Acid; Spectrum Analysis | 2009 |
Methyl-detected 'out-and-back' NMR experiments for simultaneous assignments of Alabeta and Ilegamma2 methyl groups in large proteins.
Topics: Alanine; Algorithms; Carbon Isotopes; Computer Simulation; Escherichia coli; Isoleucine; Malate Synthase; Methylation; Nuclear Magnetic Resonance, Biomolecular; Proteins; Pyruvic Acid; Valine | 2009 |
Quantitative metabolic profiles of 2nd and 3rd trimester human amniotic fluid using (1)H HR-MAS spectroscopy.
Topics: Adult; Alanine; Amniotic Fluid; Betaine; Biomarkers; Citric Acid; Creatinine; Female; Glucose; Humans; Magnetic Resonance Spectroscopy; Metabolome; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Pyruvic Acid; Young Adult | 2009 |
Kinetic modeling of hyperpolarized 13C1-pyruvate metabolism in normal rats and TRAMP mice.
Topics: Alanine; Algorithms; Animals; Carbon Isotopes; Computer Simulation; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Metabolic Clearance Rate; Mice; Mice, Transgenic; Models, Biological; Prostatic Neoplasms; Pyruvic Acid; Rats | 2010 |
Glycolysis and the tricarboxylic acid cycle are linked by alanine aminotransferase during hypoxia induced by waterlogging of Lotus japonicus.
Topics: Adenosine Triphosphate; Alanine; Alanine Transaminase; Citric Acid Cycle; Fermentation; Gene Expression Regulation, Plant; Glycolysis; Hypoxia; Leghemoglobin; Lotus; Nitrogen; Nitrogen Fixation; Pyruvic Acid; RNA Interference; Succinic Acid; Water | 2010 |
T(2) relaxation times of (13)C metabolites in a rat hepatocellular carcinoma model measured in vivo using (13)C-MRS of hyperpolarized [1-(13)C]pyruvate.
Topics: Alanine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Disease Models, Animal; Liver Neoplasms; Magnetic Resonance Spectroscopy; Male; Pyruvic Acid; Rats; Rats, Wistar | 2010 |
Production of hydrogen sulfide by two enzymes associated with biosynthesis of homocysteine and lanthionine in Fusobacterium nucleatum subsp. nucleatum ATCC 25586.
Topics: Alanine; Ammonia; Aspartate Aminotransferases; Bacterial Proteins; Cysteine Synthase; Fusobacterium nucleatum; Homocysteine; Hydrogen Sulfide; Kinetics; Pyruvic Acid; Substrate Specificity; Sulfides | 2010 |
High-resolution nuclear magnetic resonance spectroscopic study of metabolites in the cerebrospinal fluid of patients with cervical myelopathy and lumbar radiculopathy.
Topics: Acetic Acid; Adult; Aged; Aged, 80 and over; Alanine; Cervical Vertebrae; Citric Acid; Female; Glutamic Acid; Humans; Lactic Acid; Lumbar Vertebrae; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pyruvic Acid; Radiculopathy; Spinal Cord Compression | 2010 |
Redirecting reductant flux into hydrogen production via metabolic engineering of fermentative carbon metabolism in a cyanobacterium.
Topics: Acetates; Alanine; Bacterial Proteins; Carbohydrate Dehydrogenases; Carbon; Chromatography, Liquid; Genetic Engineering; Hydrogen; Lactic Acid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Metabolic Networks and Pathways; Metabolome; Oxidation-Reduction; Pyruvic Acid; Succinic Acid; Synechococcus | 2010 |
Biological hydrogen production by the algal biomass Chlorella vulgaris MSU 01 strain isolated from pond sediment.
Topics: Alanine; Anaerobiosis; Aspartic Acid; Biomass; Bioreactors; Carbon; Chlorella vulgaris; Citric Acid; Culture Media; Cysteine; Fermentation; Geologic Sediments; Glucose; Hydrogen; Hydrogen-Ion Concentration; Mannitol; Pyruvic Acid; Succinic Acid | 2011 |
Catabolic function of compartmentalized alanine dehydrogenase in the heterocyst-forming cyanobacterium Anabaena sp. strain PCC 7120.
Topics: Alanine; Alanine Dehydrogenase; Anabaena; Bacterial Proteins; Gene Expression Regulation, Bacterial; Microscopy, Confocal; Pyruvic Acid | 2010 |
Genetics and regulation of the major enzymes of alanine synthesis in Escherichia coli.
Topics: Alanine; Carbon; Culture Media; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Mutation; Pyruvic Acid; Transaminases | 2010 |
Brain glutamine synthesis requires neuronal-born aspartate as amino donor for glial glutamate formation.
Topics: Alanine; Animals; Aspartic Acid; Astrocytes; Brain Chemistry; Cells, Cultured; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Immunohistochemistry; Lactic Acid; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron; Neurons; Nitrogen; Pyruvic Acid | 2011 |
Application of double spin echo spiral chemical shift imaging to rapid metabolic mapping of hyperpolarized [1-¹³C]-pyruvate.
Topics: Alanine; Animals; Bicarbonates; Carbon Radioisotopes; Image Processing, Computer-Assisted; Kidney; Lactic Acid; Magnetic Resonance Imaging; Phantoms, Imaging; Pyruvic Acid; Rats; Software; Tritium | 2011 |
Beneficial effect of pyruvate therapy on Leigh syndrome due to a novel mutation in PDH E1α gene.
Topics: Alanine; Cells, Cultured; Child, Preschool; Dichloroacetic Acid; Electroencephalography; Fibroblasts; Humans; Lactic Acid; Leigh Disease; Male; Mutation; Pyruvate Dehydrogenase (Lipoamide); Pyruvic Acid; Statistics, Nonparametric | 2012 |
Multi-band frequency encoding method for metabolic imaging with hyperpolarized [1-(13)C]pyruvate.
Topics: Alanine; Algorithms; Animals; Carbon Isotopes; Computer Simulation; Image Processing, Computer-Assisted; Kidney; Lactic Acid; Liver; Magnetic Resonance Imaging; Male; Metabolism; Mice; Mice, Transgenic; Phantoms, Imaging; Prostatic Neoplasms; Pyruvic Acid | 2011 |
Metabolic modulation induced by oestradiol and DHT in immature rat Sertoli cells cultured in vitro.
Topics: Alanine; Animals; Biological Transport; Cells, Cultured; Dihydrotestosterone; Energy Metabolism; Estradiol; Gene Expression Regulation; Glucose; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Monocarboxylic Acid Transporters; Muscle Proteins; Pyruvic Acid; Rats; Rats, Wistar; RNA, Messenger; Sertoli Cells | 2012 |
In vivo MRSI of hyperpolarized [1-(13)C]pyruvate metabolism in rat hepatocellular carcinoma.
Topics: Alanine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Lactic Acid; Liver Neoplasms; Magnetic Resonance Spectroscopy; Pyruvic Acid; Rats; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression.
Topics: Alanine; Animals; Carbon Isotopes; Citric Acid Cycle; Disease Models, Animal; Gene Expression Profiling; Glycolysis; L-Lactate Dehydrogenase; Liver Neoplasms; Magnetic Resonance Imaging; Mice; Mice, Transgenic; Proto-Oncogene Proteins c-myc; Pyruvic Acid; Signal Transduction | 2011 |
Effects of pyruvate dose on in vivo metabolism and quantification of hyperpolarized ¹³C spectra.
Topics: Alanine; Algorithms; Animals; Bicarbonates; Carbon Isotopes; Cells; Dose-Response Relationship, Drug; Lactic Acid; Magnetic Resonance Imaging; Male; Myocardium; Phantoms, Imaging; Pyruvic Acid; Rats; Rats, Wistar; Software; Time Factors | 2012 |
Genome-enabled determination of amino acid biosynthesis in Xanthomonas campestris pv. campestris and identification of biosynthetic pathways for alanine, glycine, and isoleucine by 13C-isotopologue profiling.
Topics: Alanine; Amino Acids; Biosynthetic Pathways; Carbon Isotopes; Genetic Complementation Test; Genome, Bacterial; Glycine; Isoleucine; Magnetic Resonance Spectroscopy; Metabolic Networks and Pathways; Metabolome; Methionine; Models, Biological; Pyruvic Acid; Threonine; Xanthomonas campestris | 2011 |
In vivo measurement of normal rat intracellular pyruvate and lactate levels after injection of hyperpolarized [1-(13)C]alanine.
Topics: Alanine; Animals; Carbon Isotopes; Image Processing, Computer-Assisted; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Monocarboxylic Acid Transporters; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Signal-To-Noise Ratio | 2011 |
Revisitation of the βCl-elimination reaction of D-amino acid oxidase: new interpretation of the reaction that sparked flavoprotein dehydrogenation mechanisms.
Topics: Aerobiosis; Alanine; Anaerobiosis; Animals; Chlorine; D-Amino-Acid Oxidase; Flavins; Flavoproteins; Hydrogen-Ion Concentration; Hydrogenation; Isotopes; Kinetics; Oxidation-Reduction; Oxygen; Pyruvic Acid; Rhodotorula; Swine | 2011 |
Feeding lactate for CHO cell culture processes: impact on culture metabolism and performance.
Topics: Alanine; Animals; Carbon; Carbon Dioxide; Cell Proliferation; CHO Cells; Cricetinae; Culture Media; Energy Metabolism; Glucose; Hydrogen-Ion Concentration; Lactic Acid; Pyruvic Acid; Quaternary Ammonium Compounds | 2012 |
ald of Mycobacterium tuberculosis encodes both the alanine dehydrogenase and the putative glycine dehydrogenase.
Topics: Alanine; Alanine Dehydrogenase; Cell Membrane; Cloning, Molecular; Cytosol; Escherichia coli; Gene Expression; Gene Knockout Techniques; Glycine; Glycine Dehydrogenase; Glyoxylates; Mycobacterium tuberculosis; Nitrogen; Pyruvic Acid | 2012 |
Method for the sequential online analysis of enzyme reactions based on capillary electrophoresis.
Topics: Alanine; Electrophoresis, Capillary; Enzyme Assays; Equipment Design; Glutamic Acid; Pyruvic Acid; Reproducibility of Results; Transaminases | 2012 |
Circulating metabolite predictors of glycemia in middle-aged men and women.
Topics: Alanine; Amino Acids, Branched-Chain; Blood Glucose; Fasting; Female; Humans; Male; Middle Aged; Orosomucoid; Phenylalanine; Pyruvic Acid; Tyrosine | 2012 |
Saturation-recovery metabolic-exchange rate imaging with hyperpolarized [1-13C] pyruvate using spectral-spatial excitation.
Topics: Alanine; Animals; Bicarbonates; Carbon Isotopes; Cell Line, Tumor; Female; Lactic Acid; Magnetic Resonance Spectroscopy; Metabolic Clearance Rate; Neoplasms, Experimental; Protons; Pyruvic Acid; Radiopharmaceuticals; Rats; Rats, Inbred F344 | 2013 |
NMR studies of preimplantation embryo metabolism in human assisted reproductive techniques: a new biomarker for assessment of embryo implantation potential.
Topics: Alanine; Biomarkers; Blastocyst; Embryo Implantation; Embryo Transfer; Fertilization in Vitro; Humans; Magnetic Resonance Spectroscopy; Preimplantation Diagnosis; Pyruvic Acid | 2013 |
Effects of supplementation on food intake, body weight and hepatic metabolites in the citrin/mitochondrial glycerol-3-phosphate dehydrogenase double-knockout mouse model of human citrin deficiency.
Topics: Alanine; Animals; Body Weight; Cholestasis, Intrahepatic; Citrullinemia; Dietary Proteins; Disease Models, Animal; Eating; Female; Food, Formulated; Glycerolphosphate Dehydrogenase; Humans; Liver; Mice; Mice, Knockout; Mitochondria; Mitochondrial Membrane Transport Proteins; Pyruvic Acid; Sodium Glutamate; Sucrose; Triglycerides | 2012 |
Inhibitory effect of tumor necrosis factor α on gluconeogenesis in perfused rat liver.
Topics: Alanine; Animals; Area Under Curve; Gluconeogenesis; Glucose; Glutamine; Glycerol; Lactic Acid; Liver; Male; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Urea | 2013 |
Changes in liver gluconeogenesis during the development of Walker-256 tumour in rats.
Topics: Alanine; Animals; Carcinoma 256, Walker; Cell Proliferation; Gluconeogenesis; Glucose; Glycerol; Liver; Male; Oxygen Consumption; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Soft Tissue Neoplasms; Time Factors; Tumor Burden; Urea | 2013 |
Quantitative measurement of cancer metabolism using stimulated echo hyperpolarized carbon-13 MRS.
Topics: Alanine; Algorithms; Animals; Biomarkers, Tumor; Carbon Isotopes; Computer Simulation; Lactic Acid; Liver Neoplasms; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Models, Biological; Pyruvic Acid; Reproducibility of Results; Sensitivity and Specificity | 2014 |
Enhancing the [13C]bicarbonate signal in cardiac hyperpolarized [1-13C]pyruvate MRS studies by infusion of glucose, insulin and potassium.
Topics: Alanine; Animals; Bicarbonates; Blood Glucose; Carbon Isotopes; Glucose; Insulin; Lactates; Magnetic Resonance Spectroscopy; Male; Myocardium; Potassium; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Signal Processing, Computer-Assisted | 2013 |
In vivo magnetic resonance of hyperpolarized [(13)C1]pyruvate: metabolic dynamics in stimulated muscle.
Topics: Alanine; Algorithms; Animals; Carbon Radioisotopes; Electric Stimulation; Female; Glucose Tolerance Test; Insulin; Isotope Labeling; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred ICR; Muscles; Pyruvic Acid | 2013 |
Binding region of alanopine dehydrogenase predicted by unbiased molecular dynamics simulations of ligand diffusion.
Topics: Alanine; Amino Acid Substitution; Animals; Binding Sites; Diffusion; Helminth Proteins; Kinetics; Ligands; Molecular Dynamics Simulation; Oxidoreductases Acting on CH-NH Group Donors; Polychaeta; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Pyruvic Acid; Recombinant Proteins; Structural Homology, Protein; Substrate Specificity | 2013 |
Detection of urinary metabolomics before and after Pringle maneuver-induced liver ischemia and reperfusion injury in rats using gas chromatography-mass spectrometry.
Topics: Alanine; Alanine Transaminase; Animals; Bilirubin; Gas Chromatography-Mass Spectrometry; Glycerophosphates; Lactic Acid; Liver; Male; Metabolome; Metabolomics; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Serine | 2013 |
High altitude may alter oxygen availability and renal metabolism in diabetics as measured by hyperpolarized [1-(13)C]pyruvate magnetic resonance imaging.
Topics: Alanine; Altitude; Altitude Sickness; Animals; Atmospheric Pressure; Bicarbonates; Blood Glucose; Diabetic Nephropathies; Disease Models, Animal; Female; Humans; Hypoxia; Kidney; Lactic Acid; Magnetic Resonance Imaging; Male; Oxygen; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Wistar | 2014 |
The antineoplastic effect of carnosine is accompanied by induction of PDK4 and can be mimicked by L-histidine.
Topics: Alanine; Antineoplastic Agents; Carnosine; Cell Line, Tumor; Histidine; Humans; Protein Kinases; Pyruvic Acid; Up-Regulation | 2014 |
A computational approach to enzyme design: predicting ω-aminotransferase catalytic activity using docking and MM-GBSA scoring.
Topics: Alanine; Alanine Transaminase; Biocatalysis; Caprylates; Catalytic Domain; Crystallography, X-Ray; Humans; Molecular Dynamics Simulation; Mutation; Protein Binding; Protein Engineering; Protein Structure, Secondary; Protein Structure, Tertiary; Pyruvic Acid; Structure-Activity Relationship; Substrate Specificity; Thermodynamics | 2014 |
Structural analysis and mutant growth properties reveal distinctive enzymatic and cellular roles for the three major L-alanine transaminases of Escherichia coli.
Topics: Alanine; Alanine Transaminase; Amino Acid Sequence; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Escherichia coli; Escherichia coli Proteins; Evolution, Molecular; Gene Expression; Isoenzymes; Models, Molecular; Molecular Sequence Data; Mutation; Protein Structure, Secondary; Pyruvic Acid; Recombinant Proteins; Structural Homology, Protein; Substrate Specificity; Transaminases | 2014 |
Metabolically driven equilibrium shift of asymmetric amination of ketones by ω-transaminase using alanine as an amino donor.
Topics: Alanine; Amination; Ketones; Pyruvic Acid; Transaminases | 2014 |
Real-time assessment of ¹³C metabolism reveals an early lactate increase in the brain of rats with acute liver failure.
Topics: Alanine; Animals; Brain; Carbon; Carbon Isotopes; Computer Systems; Disease Progression; Lactic Acid; Liver Failure, Acute; Male; Pyruvic Acid; Rats, Sprague-Dawley | 2015 |
Role of L-alanine for redox self-sufficient amination of alcohols.
Topics: Alanine; Alanine Dehydrogenase; Alcohol Dehydrogenase; Alcohols; Amination; Biocatalysis; Chromobacterium; Energy Metabolism; Escherichia coli; Kinetics; Oxidation-Reduction; Plasmids; Pyruvic Acid; Transaminases; Vibrio | 2015 |
Real-time monitoring of cancer cell metabolism and effects of an anticancer agent using 2D in-cell NMR spectroscopy.
Topics: Acetates; Alanine; Antineoplastic Agents; Hep G2 Cells; Hepatocytes; Humans; Isocoumarins; L-Lactate Dehydrogenase; Metabolome; Nuclear Magnetic Resonance, Biomolecular; Pyruvic Acid | 2015 |
Metabolic responses during hemodialysis determined by quantitative (1)H NMR spectroscopy.
Topics: Aged; Alanine; Creatinine; Female; Humans; Kidney Failure, Chronic; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pyruvic Acid; Renal Dialysis; Valine | 2015 |
The progression from a lower to a higher invasive stage of bladder cancer is associated with severe alterations in glucose and pyruvate metabolism.
Topics: Alanine; Alanine Transaminase; Cell Line, Tumor; Disease Progression; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 3; Glycolysis; Humans; L-Lactate Dehydrogenase; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; Neoplasm Invasiveness; Neoplasm Staging; Phosphofructokinase-1; Pyruvic Acid; Urinary Bladder Neoplasms | 2015 |
In vitro leishmanicidal activity of 1,3-disubstituted 5-nitroindazoles.
Topics: Acetates; Alanine; Animals; Antiprotozoal Agents; Glycine; In Vitro Techniques; Indazoles; Lactic Acid; Leishmania braziliensis; Leishmania infantum; Leishmaniasis, Visceral; Macrophages; Magnetic Resonance Spectroscopy; Mice; Microscopy, Electron, Transmission; Mitochondria; Organelles; Pyruvic Acid; Succinic Acid | 2015 |
Metabolomic Analysis Reveals Increased Aerobic Glycolysis and Amino Acid Deficit in a Cellular Model of Amyotrophic Lateral Sclerosis.
Topics: Aerobiosis; Alanine; Amino Acids; Amyotrophic Lateral Sclerosis; Animals; Caspase 3; Caspase 7; Cell Death; Cell Line; Culture Media, Serum-Free; Glucose; Glutamine; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactates; Metabolome; Metabolomics; Mice; Models, Biological; Mutant Proteins; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvic Acid; Superoxide Dismutase | 2016 |
Dynamic UltraFast 2D EXchange SpectroscopY (UF-EXSY) of hyperpolarized substrates.
Topics: Alanine; Carcinoma, Renal Cell; Cell Line, Tumor; Enzyme Inhibitors; Enzymes; Humans; Kidney Neoplasms; L-Lactate Dehydrogenase; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; Nuclear Magnetic Resonance, Biomolecular; Pyruvic Acid; Reproducibility of Results; Urea | 2015 |
Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling.
Topics: Alanine; Animals; Blood Glucose; Cell Line; Citric Acid Cycle; Diabetes Mellitus, Experimental; Gluconeogenesis; Glycogen; Hepatocytes; Hyperglycemia; Intestinal Mucosa; Liver; Male; Metabolome; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Liver; Proprotein Convertase 1; Proprotein Convertase 2; Pyruvic Acid | 2015 |
Diabetes: Important role for MPC complex in hepatic gluconeogenesis.
Topics: Alanine; Animals; Glucose; Liver; Male; Mitochondria, Liver; Proprotein Convertase 1; Proprotein Convertase 2; Pyruvic Acid | 2015 |
Assessing inflammatory liver injury in an acute CCl4 model using dynamic 3D metabolic imaging of hyperpolarized [1-(13)C]pyruvate.
Topics: Alanine; Animals; Carbon Tetrachloride; Carbon-13 Magnetic Resonance Spectroscopy; Chemical and Drug Induced Liver Injury; Hepatitis; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Molecular Imaging; Pyruvic Acid; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley | 2015 |
Selective spectroscopic imaging of hyperpolarized pyruvate and its metabolites using a single-echo variable phase advance method in balanced SSFP.
Topics: A549 Cells; Alanine; Algorithms; Animals; Biomarkers, Tumor; Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Lactic Acid; Magnetic Resonance Imaging; Mice; Mice, Nude; Molecular Imaging; Neoplasms, Experimental; Pyruvic Acid; Reproducibility of Results; Sensitivity and Specificity; Signal Processing, Computer-Assisted | 2016 |
Metabolism of hyperpolarized [1-(13)C]pyruvate through alternate pathways in rat liver.
Topics: Alanine; Animals; Bicarbonates; Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Citric Acid Cycle; Gluconeogenesis; Lactic Acid; Liver; Magnetic Resonance Spectroscopy; Phosphoenolpyruvate Carboxykinase (ATP); Proton Magnetic Resonance Spectroscopy; Pyruvate Carboxylase; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats, Sprague-Dawley | 2016 |
Efficient production of the Nylon 12 monomer ω-aminododecanoic acid methyl ester from renewable dodecanoic acid methyl ester with engineered Escherichia coli.
Topics: Alanine; Biosynthetic Pathways; Conservation of Natural Resources; Escherichia coli; Genetic Enhancement; Lauric Acids; Metabolic Engineering; Metabolic Networks and Pathways; Nylons; Pyruvic Acid; Recombinant Proteins | 2016 |
Ex vivo hyperpolarized MR spectroscopy on isolated renal tubular cells: A novel technique for cell energy phenotyping.
Topics: Alanine; Animals; Bicarbonates; Carbon Isotopes; Cells, Cultured; Cytological Techniques; Kidney Cortex; Kidney Tubules; Lactic Acid; Magnetic Resonance Imaging; Phenotype; Pyruvic Acid; Rats; Rats, Wistar | 2017 |
In situ lactate dehydrogenase activity: a novel renal cortical imaging biomarker of tubular injury?
Topics: Acute Kidney Injury; Alanine; Animals; Bicarbonates; Biomarkers; Carbon Isotopes; Disease Models, Animal; Isoenzymes; Kidney Tubules; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Magnetic Resonance Imaging; Male; Predictive Value of Tests; Prognosis; Pyruvic Acid; Rats, Wistar; Reperfusion Injury; Time Factors | 2017 |
Imaging porcine cardiac substrate selection modulations by glucose, insulin and potassium intervention: A hyperpolarized [1-
Topics: Alanine; Animals; Bicarbonates; Carbon Isotopes; Female; Glucose; Imaging, Three-Dimensional; Insulin; Lactic Acid; Magnetic Resonance Spectroscopy; Monitoring, Physiologic; Potassium; Pyruvic Acid; Sus scrofa | 2017 |
Comparative studies of the catalytic mechanisms of two chorismatases: CH-fkbo and CH-Hyg5.
Topics: Alanine; Amino Acid Motifs; Bacterial Proteins; Biocatalysis; Catalytic Domain; Chorismic Acid; Cysteine; Glycine; Hydrolysis; Kinetics; Models, Molecular; Oxo-Acid-Lyases; Protons; Pyruvic Acid; Quantum Theory; Streptomyces; Structure-Activity Relationship; Thermodynamics | 2017 |
Implications of epigallocatechin-3-gallate in cultured human Sertoli cells glycolytic and oxidative profile.
Topics: Alanine; Catechin; Cell Proliferation; Cells, Cultured; Glucose; Glucose Transporter Type 2; Glycolysis; Humans; L-Lactate Dehydrogenase; Male; Membrane Potential, Mitochondrial; Monocarboxylic Acid Transporters; Muscle Proteins; Oxidative Stress; Pyruvic Acid; Sertoli Cells | 2017 |
Dynamic nuclear polarization facilitates monitoring of pyruvate metabolism in
Topics: Alanine; Algorithms; Animals; Carbon Dioxide; Carbon Isotopes; Cells, Immobilized; Energy Metabolism; Gastrointestinal Tract; HEK293 Cells; Hep G2 Cells; Humans; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Trypanosoma brucei brucei; Trypanosomiasis; Tsetse Flies | 2017 |
Bifunctional alanine dehydrogenase from the halotolerant cyanobacterium Aphanothece halophytica: characterization and molecular properties.
Topics: Alanine; Alanine Dehydrogenase; Bacterial Proteins; Cyanobacteria; Enzyme Induction; Escherichia coli; Gene Expression Regulation, Bacterial; Glyoxylates; Hydrogen-Ion Concentration; Kinetics; Pyruvic Acid; Salt Tolerance; Substrate Specificity | 2018 |
High spatiotemporal resolution bSSFP imaging of hyperpolarized [1-
Topics: Adenocarcinoma; Alanine; Animals; Carbon Isotopes; Image Processing, Computer-Assisted; Lactic Acid; Magnetic Resonance Imaging; Male; Mice; Neoplasm Transplantation; Prostatic Neoplasms; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Time Factors; Transgenes | 2018 |
Understanding the high L-valine production in Corynebacterium glutamicum VWB-1 using transcriptomics and proteomics.
Topics: Alanine; Corynebacterium glutamicum; Leucine; NADP; Proteomics; Pyruvic Acid; Transcriptome; Valine | 2018 |
Plant-microbe competition: does injection of isotopes of C and N into the rhizosphere effectively characterise plant use of soil N?
Topics: Alanine; Carbon Dioxide; Carbon Isotopes; Minerals; Nitrogen; Nitrogen Isotopes; Plant Roots; Plants; Pyruvic Acid; Rhizosphere; Soil; Soil Microbiology; Triticum | 2019 |
pH controlled byproduct formation in aqueous decomposition of N-chloro-α-alanine.
Topics: Alanine; Aldehydes; Anions; Carbon; Chlorine; Hydrogen-Ion Concentration; Hydroxides; Hypochlorous Acid; Ions; Kinetics; Magnetic Resonance Spectroscopy; Propionates; Pyruvates; Pyruvic Acid; Spectrophotometry, Ultraviolet; Water; Water Purification | 2019 |
Hyperpolarized [1-
Topics: Alanine; Animals; Blood Glucose; Citric Acid Cycle; Fatty Acids; Female; Glucagon; Insulin; Lactic Acid; Liver Diseases; Magnetic Resonance Imaging; Pyruvic Acid; Swine | 2018 |
Effects of deuteration on transamination and oxidation of hyperpolarized
Topics: Alanine; Alanine Transaminase; Amination; Animals; Carbon Isotopes; Deuterium; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardium; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Water | 2019 |
Pyruvate Homeostasis as a Determinant of Parasite Growth and Metabolic Plasticity in Toxoplasma gondii.
Topics: Alanine; Carbon; Homeostasis; Lactic Acid; Metabolomics; Protozoan Proteins; Pyruvic Acid; Toxoplasma | 2019 |
LKB1 specifies neural crest cell fates through pyruvate-alanine cycling.
Topics: Alanine; AMP-Activated Protein Kinases; Animals; Cell Differentiation; Energy Metabolism; Enteric Nervous System; Gene Silencing; Melanocytes; Mice; Mice, Knockout; Mitochondria; Nerve Degeneration; Neural Crest; Neuroglia; Peripheral Nervous System Diseases; Phenotype; Protein Serine-Threonine Kinases; Pyruvic Acid; Signal Transduction | 2019 |
Rational modification of the carbon metabolism of Corynebacterium glutamicum to enhance L-leucine production.
Topics: Alanine; Carbon; Citric Acid Cycle; Corynebacterium glutamicum; Fermentation; Industrial Microbiology; Leucine; Metabolic Engineering; Plasmids; Pyruvic Acid; Transaminases; Valine | 2020 |
Serine restriction alters sphingolipid diversity to constrain tumour growth.
Topics: Alanine; Animals; Cell Adhesion; Cell Division; Diet; Female; Glycine; HCT116 Cells; Humans; Membrane Lipids; Mice; Mitochondria; Neoplasms; Phosphoglycerate Dehydrogenase; Pyruvic Acid; Serine; Serine C-Palmitoyltransferase; Spheroids, Cellular; Sphingolipids; Stress, Physiological; Xenograft Model Antitumor Assays | 2020 |
Biotransformation and chiral resolution of d,l-alanine into pyruvate and d-alanine with a whole-cell biocatalyst expressing l-amino acid deaminase.
Topics: Alanine; Ammonia-Lyases; Bacterial Proteins; Escherichia coli; Gene Expression; Microorganisms, Genetically-Modified; Proteus mirabilis; Pyruvic Acid | 2020 |
Non-invasive assessment of telomere maintenance mechanisms in brain tumors.
Topics: Alanine; Animals; Biomarkers, Tumor; Brain Neoplasms; Carbon Isotopes; Cell Line, Tumor; Genetic Engineering; Glioma; Lactic Acid; Male; Metabolome; Models, Biological; Neoplasm Grading; Neoplasm Proteins; Proton Magnetic Resonance Spectroscopy; Pyruvic Acid; Rats, Nude; RNA, Messenger; Telomerase; Telomere; Telomere Homeostasis; Xenograft Model Antitumor Assays | 2021 |
Structural characterization of a 2-aminoethylphosphonate:pyruvate aminotransferase from Pseudomonas aeruginosa PAO1.
Topics: Acetaldehyde; Alanine; Amino Acid Sequence; Aminoethylphosphonic Acid; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Models, Molecular; Protein Conformation; Protein Multimerization; Pseudomonas aeruginosa; Pyridoxal Phosphate; Pyruvic Acid; Recombinant Proteins; Sequence Homology, Amino Acid; Transaminases | 2021 |
Gluconeogenesis is reduced from alanine, lactate and pyruvate, but maintained from glycerol, in liver perfusion of rats with early and late sepsis.
Topics: Alanine; Animals; Gluconeogenesis; Glycerol; Lactic Acid; Liver; Male; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Sepsis | 2021 |
The mitochondrial pyruvate carrier (MPC) complex mediates one of three pyruvate-supplying pathways that sustain Arabidopsis respiratory metabolism.
Topics: Acrylates; Alanine; Alanine Transaminase; Anion Transport Proteins; Arabidopsis; Arabidopsis Proteins; Biological Transport; Cycloserine; Enzyme Inhibitors; Malate Dehydrogenase; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Monocarboxylic Acid Transporters; Multiprotein Complexes; NAD; Plants, Genetically Modified; Pyruvic Acid | 2021 |
Hyperpolarized pyruvate to measure the influence of PKM2 activation on glucose metabolism in the healthy kidney.
Topics: Alanine; Animals; Bicarbonates; Disease Models, Animal; Enzyme Activation; Glucose; Glycolysis; Hematocrit; Humans; Hydrogen-Ion Concentration; Kidney; Lactic Acid; Male; Pyruvate Kinase; Pyruvic Acid; Rats, Wistar | 2021 |
Mitochondrial enzyme GPT2 regulates metabolic mechanisms required for neuron growth and motor function in vivo.
Topics: Alanine; Alanine Transaminase; Animals; Disabled Persons; Humans; Mice; Mice, Knockout; Motor Disorders; Neurons; Pyruvic Acid; Transaminases | 2022 |
Comprehensively understanding metabolic pathways of protein during the anaerobic digestion of waste activated sludge.
Topics: Acetyl Coenzyme A; Alanine; Amino Acids; Anaerobiosis; Arginine; Glutamates; Glycine; Histidine; Leucine; Lysine; Metabolic Networks and Pathways; Methionine; Phenylalanine; Pyruvic Acid; Serine; Sewage; Threonine; Tyrosine | 2022 |
Engineering Novel (
Topics: Alanine; Amino Acids; Ascomycota; Catalytic Domain; Pyruvic Acid; Transaminases | 2022 |
Alanine synthesized by alanine dehydrogenase enables ammonium-tolerant nitrogen fixation in
Topics: Alanine; Alanine Dehydrogenase; Ammonium Compounds; Nitrogen; Nitrogen Fixation; Nitrogenase; Pyruvic Acid | 2022 |
Consumption and Metabolism of Extracellular Pyruvate by Cultured Rat Brain Astrocytes.
Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Astrocytes; Brain; Carrier Proteins; Lactates; Pyruvic Acid; Rats | 2023 |
Application of reductive amination by heterologously expressed Thermomicrobium roseumL-alanine dehydrogenase to synthesize L-alanine derivatives.
Topics: Alanine; Alanine Dehydrogenase; Amination; Amino Acid Oxidoreductases; Amino Acids; Pyruvic Acid; Substrate Specificity | 2023 |