alanine has been researched along with pyridoxal phosphate in 167 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 92 (55.09) | 18.7374 |
| 1990's | 29 (17.37) | 18.2507 |
| 2000's | 26 (15.57) | 29.6817 |
| 2010's | 14 (8.38) | 24.3611 |
| 2020's | 6 (3.59) | 2.80 |
| Authors | Studies |
|---|---|
| Beeler, T; Churchich, JE; Oh, KJ | 1 |
| Charington, CB; Tsui, D; Wood, JD | 1 |
| Azarian, AV; Egorov, TsA; Mekhanik, ML; Torchinskiĭ, IuM | 1 |
| Lustig, V | 1 |
| Hershey, SA; Leussing, DL | 1 |
| Davis, L; Jo, BH; Nair, V | 1 |
| Abeles, RH; Silverman, RB | 1 |
| Dalling, DK; Grant, DM; Horton, WJ; Sagers, RD | 1 |
| Kumagai, H; Utagawa, T; Yamada, H | 1 |
| Walker, JB | 1 |
| Rando, RR | 1 |
| Moriguchi, M; Soda, K; Tanizawa, K | 1 |
| Cooper, AJ | 1 |
| Bhatia, MB; Manning, JM; Ringe, D; Soda, K; Yoshimura, T | 1 |
| Bhatia, MB; Futaki, S; Manning, JM; Martinez del Pozo, A; Ringe, D; Soda, K; Yoshimura, T | 1 |
| Esaki, N; Futaki, S; Manning, JM; Nishimura, K; Soda, K; Tanizawa, K; Yoshimura, T | 1 |
| Brzović, P; Dunn, MF; Greene, RC; Holbrook, EL | 1 |
| Fasella, P; Lucano, A; Salerno, C | 1 |
| Bauer, SC; Bild, GS; Borgmeyer, JR; Huynh, QK; Kishore, GM | 1 |
| Kiick, DM; Phillips, RS | 2 |
| Barry, RJ; Bowman, E; Dunaway-Mariano, D; McQueney, M | 1 |
| Der Garabedian, PA; Lotti, AM; Vermeersch, JJ | 1 |
| Curzon, G; Green, AR | 1 |
| Bruice, TC; Shinkai, S | 1 |
| Hall, ZW; Kravitz, EA | 1 |
| Miyake, Y; Yamano, T | 1 |
| Abe, T; Miyake, Y; Yamano, T | 1 |
| Bergquist, A; LaBrie, DA; Leiter, EH; Wagner, RP | 1 |
| Barker, HA; Jeng, IM; Somack, R | 1 |
| Lipsett, MN | 1 |
| Hayaishi, O; Inoue, K; Kurosawa, A; Shizuta, Y; Tanabe, T | 1 |
| Soda, K | 1 |
| John, RA; Tudball, N | 1 |
| Blanck, TJ; Dunathan, HC; Hindenlang, DM; Kallen, RG; Ulevitch, RJ; Voet, JG | 1 |
| Kaplan, JG; McDonald, RA | 1 |
| Evered, DF; Hargreaves, BM | 1 |
| Fukui, S; Kumagai, H; Masugi, F; Yamada, H | 1 |
| Meister, A; Relyea, NM; Tate, SS | 1 |
| Florent'ev, VL; Mamaeva, OK; Padyukova, NSh | 1 |
| Kumagai, H; Matsui, H; Ogata, K; Ohkishi, H; Yamada, H | 2 |
| Conn, EE; Floss, HG; Hadwiger, L | 1 |
| Baumgarten, J; Schlegel, HG | 1 |
| Crawford, IP; Maurer, R | 1 |
| Heinemann, MA; Joseph, AA; Semeraro, RJ; Wixom, RL | 1 |
| Misono, H; Soda, K; Toyama, S | 1 |
| Martin, WG; Sass, NL | 1 |
| Piszkiewicz, D; Smith, EL; Veronese, FM | 1 |
| Snell, EE | 1 |
| Flavin, M; Posner, BI | 1 |
| Braunstein, AE; Goryachenkova, EV; Tolosa, EA; Willhardt, IH; Yefremova, LL | 1 |
| Moriguchi, M; Soda, K; Yamamoto, T | 2 |
| Okuyama, T; Suzuki, T | 1 |
| Dixon, HB; Van Heyningen, S | 1 |
| Diven, WF; Johnston, MM | 1 |
| Bradford, HF; Thomas, AJ | 1 |
| Adams, E | 2 |
| Kashima, N; Kumagai, H; Yamada, H | 1 |
| Ekstrom, CG; Felty, WL; Leussing, DL | 1 |
| Bailey, GB; Chotamangsa, O; Vuttivej, K | 1 |
| Chatagner, F; Dème, D; Durieu-Trautmann, O | 1 |
| Diller, A; Schirch, LV | 1 |
| Giovanelli, J; Mudd, SH | 1 |
| Giovanelli, J; Mudd, SH; Owens, LD | 1 |
| Misono, H; Soda, K; Yorifuji, T | 1 |
| Adams, E; Rosso, G; Takashima, K | 1 |
| Meister, A; Tate, SS | 1 |
| Osumi, T; Soda, K | 1 |
| Husain, MM; Rao, VK | 1 |
| Jenkins, WT; Martinez-Carrion, M | 1 |
| Matchett, WH | 1 |
| Gale, GR; Hynes, JB | 1 |
| Ikawa, M | 1 |
| Massieu, GH; Ortega, BG; Pasantes, H; Pérez de la Mora, M; Tapia, R | 1 |
| Pfeffer, M; Ressler, C | 1 |
| Tyce, GM; Wong, KL | 1 |
| Engel, PC; Syed, SE | 1 |
| Cohen, LA; Miles, EW; Phillips, RS | 1 |
| Davis, MP; Jillson, L; Johnston, RB; Kirker, ME; Schreiber, EC; Sorrell, WT | 1 |
| Nagasawa, T; Ohkishi, H; Yamada, H | 1 |
| Roise, D; Soda, K; Walsh, CT; Yagi, T | 1 |
| Hosono, H; Kawakami, B; Nagasawa, T; Ohkishi, H; Tani, Y; Yamada, H; Yamano, H | 1 |
| Dye, JL; June, DS; Suelter, CH | 1 |
| Bergmeyer, HU; Hørder, M | 1 |
| Esaki, N; Kishimoto, K; Manning, JM; Soda, K; Sugio, S; Yoshimura, T | 1 |
| Bukrina, IM; Dixon, HB; Khristoforov, RR; Krasnov, VP; Sparkes, MJ; Sukhareva, BS | 1 |
| Belikov, VM; Dementieva, IS; Faleev, NG; Gogoleva, OI; Zakomirdina, LN | 1 |
| Hayashi, H; Hirotsu, K; Kagamiyama, H; Kuramitsu, S; Metzler, CM; Metzler, DE; Miyahara, I; Mollova, ET; Scott, RD; Yano, T | 1 |
| el-Rahmany, TA | 1 |
| Kahana, C; Tobias, KE | 1 |
| Manning, JM; Peisach, D; Petsko, G; Pospischil, MA; Ringe, D; Soda, K; Van Ophem, PW | 1 |
| Olson, GT; Silverman, RB | 1 |
| Marquet, A; Ploux, O | 1 |
| Flint, DH | 1 |
| Cook, PF; Dunn, MF; Hwang, CC; Schnackerz, KD; Tai, CH; Woehl, EU | 1 |
| Clausen, T; Huber, R; Laber, B; Messerschmidt, A; Pohlenz, HD | 1 |
| Cook, PF; Karsten, WE; Kredich, NM; Rege, VD; Schnackerz, KD; Tai, CH | 1 |
| Honma, M; Ito, H; Kiuchi, M; Matsui, H; Murakami, T | 1 |
| Bertoldi, M; Castellani, S; Dominici, P; Moore, PS; Voltattorni, CB | 1 |
| Preiss, J; Sheng, J | 1 |
| Chait, BT; Erickson, SD; Haller, I; Manning, JM; Martinez del Pozo, A; Petsko, G; Ringe, D; Soda, K; van Ophem, PW; Yoshimura, T | 1 |
| Jhee, KH; McPhie, P; Miles, EW; Ro, HS | 1 |
| Hayashi, H; Kagamiyama, H; Mizuguchi, H | 1 |
| Di Pietro, MC; Guerranti, R; Leoncini, R; Marinello, E; Pagani, R; Rosi, F; Vannoni, D | 1 |
| Alexeev, D; Alexeeva, M; Baxter, RL; Campopiano, DJ; Sawyer, L; Webster, SP | 1 |
| Breyne, O; Carillon, S; Marquet, A; Ploux, O | 1 |
| Esaki, N; Kurihara, T; Kurokawa, Y; Soda, K; Watababe, A; Watanabe, A; Yoshimura, T | 1 |
| Ro, HS; Wilson Miles, E | 1 |
| Jansonius, JN; Keller, JW; Malashkevich, VN; Strop, P; Toney, MD | 1 |
| Prakash, V; Rao, JV; Rao, NA; Savithri, HS | 1 |
| Esaki, N; Hirotsu, K; Jhee, KH; Kawata, Y; Miles, EW; Miyahara, I; Soda, K; Takeda, S; Yoshimura, T | 1 |
| Chen, X; Dieckmann, T; Jin, X; Medhekar, R; Toney, MD; Zhou, X | 1 |
| Homma, H; Imai, K; Kamo, N; Lee, JA; Long, Z; Maruyama, T; Nimura, N; Okamoto, T; Oshima, T; Sekine, M; Sumi, M; Yamagishi, A; Yohda, M | 1 |
| Beránek, M; Drsata, J; Palicka, V | 1 |
| Toney, MD; Zabinski, RF | 1 |
| Cook, PF; Daum, S; Tai, CH | 1 |
| MASSIEU, GH; ORTEGA, BG; PASANTES, H; TAPIA, R | 1 |
| EISENSTEIN, AB | 1 |
| DOBSON, MB; DURHAM, NN; FERGUSON, D; KUDLAC, JJ | 1 |
| DIVEN, WF; JOHNSTON, RB; SCHOLZ, JJ | 1 |
| MEISTER, A; NOVOGRODSKY, A; SODA, K | 1 |
| AASLESTAD, HG; LARSON, AD | 1 |
| DURHAM, NN; FERGUSON, D; JACOBS, CD | 1 |
| JENKINS, WT; SCHIRCH, L | 1 |
| GRULA, EA; GRULA, MM | 1 |
| Chang, SJ; Hsiao, LJ; Hsuen, SY | 1 |
| Connolly, SA; Francklyn, CS; Musier-Forsyth, K; Rosen, AE | 1 |
| Blagova, L; Levdikov, V; Lima, S; Momany, C; Phillips, RS | 1 |
| Mouratou, B; Stetefeld, J | 1 |
| Amyes, TL; Malthouse, JP; NíBeilliú, ME; Richard, JP; Toth, K | 1 |
| Akella, R; Baldwin, J; Goldsmith, EJ; Jackson, LK; Phillips, MA | 1 |
| Chen, HY; Lima, S; Phillips, RS; Shim, D; Sundararaju, B; Tavakoli, K | 1 |
| Banerjee, R; Zou, CG | 1 |
| Golinelli-Pimpaneau, B | 1 |
| Fujitani, Y; Ishihara, K; Ito, K; Nakajima, N; Oikawa, T; Sugimoto, M | 1 |
| Gao, J; Major, DT; Nam, K | 1 |
| Gao, YG; Han, Q; Li, J; Rizzi, M; Robinson, H; Vogelaar, N; Wilson, SR | 1 |
| Ishii, Y; Kawada, T; Nagata, Y; Nakamoto, Y; Nishimura, K; Tomoda, Y | 1 |
| Ferreira, GC; Hunter, GA; Turbeville, TD; Zhang, J | 1 |
| Fesko, K; Giger, L; Hilvert, D | 1 |
| Inada, A; Ozaki, S; Sada, K | 1 |
| Ju, J; Li, G; Ma, Y; Ohnishi, K; Wen, J; Xu, S; Xue, Y | 1 |
| Bertoldi, M; Voltattorni, CB | 1 |
| Ichiyama, A; Mugiya, S; Nagata, M; Oda, T; Ozono, S; Takayama, T | 1 |
| Imperiali, B; Larkin, A; Olivier, NB | 1 |
| Joo, K; Kim, BG; Kyung, D; Lee, J; Seo, JH | 1 |
| Cellini, B; Fodor, K; Oppici, E; Paiardini, A; Voltattorni, CB; Williams, C; Wilmanns, M | 1 |
| Banerjee, R; Chi, YY; DeRatt, BN; Gregory, JF; Kabil, O; Ralat, MA | 1 |
| Anufrieva, NV; Demidkina, TV; Faleev, NG; Fedorova, OS; Kuznetsov, NA; Kuznetsova, AA; Morozova, EA; Nikulin, AD; Revtovich, SV | 1 |
| Ding, H; Lu, J; Tan, G; White, RH; Yang, J; Zhang, T | 1 |
| Borri Voltattorni, C; Cellini, B; Dindo, M; Gotte, G; Montioli, R; Oppici, E; Roncador, A | 1 |
| Calvo, AC; Cellini, B; Mesa-Torres, N; Miranda-Vizuete, A; Montioli, R; Oppici, E; Pey, AL; Salido, E; Titelbaum, N | 1 |
| Han, R; Kong, X; Ni, Y; Xu, G; Zhang, K; Zhou, J; Zhu, H | 1 |
| Altegoer, F; Bange, G; Blauenburg, B; Fage, CD; Linne, U; Marahiel, MA; Mielcarek, A | 1 |
| Cellini, B; Cutruzzolà, F; Giardina, G; Montioli, R; Paiardini, A; Voltattorni, CB | 1 |
| Homma, H; Katane, M; Miyamoto, T; Saitoh, Y; Sekine, M | 1 |
| Boyden, ES; Hernández-Vivanco, A; Martín-Fernández, M; Mederos, S; Navarrete, M; Perea, G; Ramírez-Franco, J; Yang, A | 1 |
| Mothersole, RG; Wolthers, KR | 1 |
| Bartlam, M; Chen, Y; Jia, H; Liu, R; Zhang, Q | 1 |
| Bogie, PM; Bosken, YK; Caulkins, BG; Chang, CA; Drago, VN; Dunn, MF; Ghosh, RK; Gill, AD; Guidoulianov, J; Hassan, A; Hilario, E; Holmes, JB; Hooley, RJ; Liu, V; Long, JR; Mentink-Vigier, F; Mueller, LJ; Mueser, TC; Paulino, J; Perrone, B; Riviere, G; Romero, JA; Struppe, J; Wang, X; Young, RP | 1 |
| Campopiano, DJ; Harrison, PJ; Herrera, MA; Ortiz, GP; Richardson, SM; Verez, R; Wang, M | 1 |
| Tsuchida, N; Yamabe, S; Yamazaki, S | 1 |
| Frank, MW; Miller, DJ; Radka, CD; Rock, CO | 1 |
| Bakunova, AK; Bezsudnova, EY; Kostyukov, AA; Kuzmin, VA; Popov, VO | 1 |
2 review(s) available for alanine and pyridoxal phosphate
| Article | Year |
|---|---|
[Amino acid racemases (author's transl)].
Topics: Adenosine Triphosphate; Alanine; Amino Acid Isomerases; Arginine; Chemical Phenomena; Chemistry; Coenzymes; Flavin-Adenine Dinucleotide; Glutamine; Hydrogen-Ion Concentration; Hydroxyproline; Magnetic Resonance Spectroscopy; Molecular Weight; Phenylalanine; Pyridoxal Phosphate; Spectrophotometry | 1974 |
Redox regulation and reaction mechanism of human cystathionine-beta-synthase: a PLP-dependent hemesensor protein.
Topics: Alanine; Allosteric Regulation; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Crystallography, X-Ray; Cystathionine beta-Synthase; DNA Mutational Analysis; Enzyme Activation; Heme; Hemeproteins; Humans; Kinetics; Models, Chemical; Models, Molecular; Models, Structural; Molecular Sequence Data; Molecular Structure; Molecular Weight; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Substrate Specificity; Threonine | 2005 |
165 other study(ies) available for alanine and pyridoxal phosphate
| Article | Year |
|---|---|
Nonequivalent binding sites in cystathionase. Nanosecond and steady fluorescence studies.
Topics: Alanine; Amino Acids; Animals; Binding Sites; Cystathionine gamma-Lyase; Enzyme Activation; Homoserine; Hydrogen-Ion Concentration; Kinetics; Liver; Lyases; Protein Binding; Pyridoxal Phosphate; Rats; Spectrometry, Fluorescence; Time Factors | 1975 |
Alteration of GABA metabolism in mammalian brain by l-alpha-amino-beta-chloropropionic acid hydroxamide and related compounds.
Topics: 4-Aminobutyrate Transaminase; Alanine; Animals; Anticonvulsants; Brain; gamma-Aminobutyric Acid; Male; Mice; Pyridoxal Phosphate; Time Factors | 1979 |
[Study of the role of arginine residues in aspartate transaminase from chicken heart cytosol].
Topics: Alanine; Animals; Apoenzymes; Aspartate Aminotransferases; Chemical Phenomena; Chemistry; Chickens; Circular Dichroism; Cyclohexanones; Cytosol; Kinetics; Myocardium; Pyridoxal Phosphate | 1978 |
Activation of alanine aminotransferase in serum by pyridoxal phosphate.
Topics: Alanine; Alanine Transaminase; Enzyme Activation; Humans; Ketoglutaric Acids; Pyridoxal Phosphate | 1977 |
Rate carbinolamine formation between pridoxal 5'-phospage and alanine.
Topics: Alanine; Amino Alcohols; Chemical Phenomena; Chemistry; Kinetics; Pyridoxal Phosphate | 1977 |
Carbon-13 nuclear magnetic resonance studies of vitamin B6 Schiff base and carbinolamine formation in aqueous solution.1 1. The adduct of pyridoxal 5'-phosphate and DL-alanine.
Topics: Alanine; Amino Alcohols; Chemical Phenomena; Chemistry; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Pyridoxine; Schiff Bases; Solutions | 1977 |
Inactivation of pyridoxal phosphate dependent enzymes by mono- and polyhaloalanines.
Topics: Alanine; Alanine Transaminase; Aspartate Aminotransferases; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Kinetics; L-Serine Dehydratase; Lyases; Pyridoxal Phosphate; Threonine Dehydratase; Tryptophan Synthase; Tryptophanase | 1976 |
Carbon 13 NMR study of nonenzymatic reactions of pyridoxal 5'-phosphate with selected amino acids and of related reactions.
Topics: Alanine; Amino Acids; Ammonia; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Formaldehyde; Glycine; Magnetic Resonance Spectroscopy; Molecular Conformation; Pyridoxal Phosphate; Pyridoxamine; Sarcosine; Structure-Activity Relationship | 1976 |
Studies on tyrosine phenol lyase. Modification of essential histidyl residues by diethylpyrocarbonate.
Topics: Alanine; Binding Sites; Borohydrides; Escherichia coli; Esters; Formates; Histidine; Hydroxylamines; Lyases; Phenols; Protein Binding; Pyridoxal Phosphate; Structure-Activity Relationship; Sulfhydryl Compounds; Tyrosine | 1975 |
L-alanine61D-1-guanidino-1-deoxy-3-deto-scyllo-inositol aminotransferase.
Topics: Alanine; Alkaline Phosphatase; Drug Stability; Escherichia coli; Guanidines; Inositol; Ketoses; Methods; Pyridoxal Phosphate; Species Specificity; Streptomyces; Streptomycin; Transaminases | 1975 |
On the mechanism of action of antibiotics which act as irreversible enzyme inhibitors.
Topics: Alanine; Anti-Bacterial Agents; Asparagine; Azaserine; Azo Compounds; Carbamates; Catalysis; Cell Wall; Cephalosporins; Cycloserine; Diazooxonorleucine; Enzyme Inhibitors; Glutamine; Models, Chemical; Models, Molecular; Penicillins; Purines; Pyridoxal Phosphate; Pyrimidines; Racemases and Epimerases; Serine | 1975 |
Regulation of the activity of microbial kynureninase by transamination of the enzyme-bound coenzyme.
Topics: Alanine; Hydrolases; Kynurenine; Protein Binding; Pseudomonas; Pyridoxal Phosphate; Pyruvates; Spectrophotometry; Transaminases | 1975 |
Proton magnetic resonance studies of glutamate-alanine transaminase-catalyzed deuterium exchange. Evidence for proton conservation during prototropic transfer from the alpha carbon of L-alanine to the C4-position of pyridoxal 5'-phosphate.
Topics: Alanine; Alanine Transaminase; Binding Sites; Chemical Phenomena; Chemistry; Deuterium; Fourier Analysis; Kinetics; Magnetic Resonance Spectroscopy; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Temperature | 1976 |
Partial reactions of bacterial D-amino acid transaminase with asparagine substituted for the lysine that binds coenzyme pyridoxal 5'-phosphate.
Topics: Alanine; Asparagine; Base Sequence; beta-Alanine; Binding Sites; Borohydrides; Catalysis; D-Alanine Transaminase; Ethanolamine; Ethanolamines; Geobacillus stearothermophilus; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Pyridoxal Phosphate; Spectrophotometry; Structure-Activity Relationship; Transaminases | 1992 |
Inactivation of dimeric D-amino acid transaminase by a normal substrate through formation of an unproductive coenzyme adduct in one subunit.
Topics: Alanine; D-Alanine Transaminase; Endopeptidases; Enzyme Activation; Enzyme Reactivators; Hydrogen-Ion Concentration; Kinetics; Pyridoxal Phosphate; Pyridoxamine; Pyruvates; Pyruvic Acid; Spectrometry, Fluorescence; Transaminases | 1992 |
Effect of substitution of a lysyl residue that binds pyridoxal phosphate in thermostable D-amino acid aminotransferase by arginine and alanine.
Topics: Alanine; Alanine Transaminase; Arginine; Base Sequence; Cloning, Molecular; D-Alanine Transaminase; Enzyme Stability; Escherichia coli; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Plasmids; Pyridoxal Phosphate; Recombinant Proteins; Restriction Mapping; Spectrophotometry; Thermodynamics | 1991 |
Reaction mechanism of Escherichia coli cystathionine gamma-synthase: direct evidence for a pyridoxamine derivative of vinylglyoxylate as a key intermediate in pyridoxal phosphate dependent gamma-elimination and gamma-replacement reactions.
Topics: Alanine; Allylglycine; Carbon-Oxygen Lyases; Cysteine; Escherichia coli; Fatty Acids, Monounsaturated; Homoserine; Kinetics; Lyases; Molecular Structure; Pyridoxal Phosphate; Pyridoxamine; Spectrophotometry; Spectrophotometry, Ultraviolet | 1990 |
Pyridoxal phosphate-dependent reactions in water pools.
Topics: Alanine; Aspartate Aminotransferases; Colloids; Dioctyl Sulfosuccinic Acid; Hydrogen-Ion Concentration; Isomerism; Micelles; Octanes; Osmolar Concentration; Pyridoxal Phosphate; Spectrophotometry; Surface-Active Agents; Water | 1989 |
Site-directed mutagenesis of Petunia hybrida 5-enolpyruvylshikimate-3-phosphate synthase: Lys-23 is essential for substrate binding.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alanine; Alkyl and Aryl Transferases; Arginine; Binding Sites; Binding, Competitive; Glutamates; Glutamic Acid; Glycine; Glyphosate; Herbicides; Lysine; Mutation; Phosphoenolpyruvate; Plants; Pyridoxal Phosphate; Shikimic Acid; Transferases | 1988 |
Mechanistic deductions from multiple kinetic and solvent deuterium isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Escherichia coli tryptophan indole-lyase.
Topics: Alanine; Binding, Competitive; Catalysis; Cysteine; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lyases; Oxindoles; Pyridoxal Phosphate; Solvents; Tryptophan; Tryptophanase | 1988 |
Elucidation of the 2-aminoethylphosphonate biosynthetic pathway in Tetrahymena pyriformis.
Topics: Acetaldehyde; Alanine; Aminoethylphosphonic Acid; Animals; Magnesium; Magnesium Chloride; Organophosphorus Compounds; Phosphoenolpyruvate; Pyridoxal Phosphate; Pyruvates; Tetrahymena pyriformis; Thiamine Pyrophosphate | 1988 |
Mechanistic deductions from kinetic isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Erwinia herbicola and Citrobacter freundii tyrosine phenol-lyase.
Topics: Alanine; Binding, Competitive; Citrobacter; Cysteine; Deuterium; Erwinia; Hydrogen-Ion Concentration; Kinetics; Lyases; Phenylalanine; Pyridoxal Phosphate; Tyrosine; Tyrosine Phenol-Lyase | 1988 |
4-Aminobutyrate:2-oxoglutarate aminotransferase from Candida. Purification and properties.
Topics: 4-Aminobutyrate Transaminase; Alanine; Aminobutyrates; Butyrates; Butyric Acid; Candida; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Isoelectric Point; Kinetics; Molecular Weight; Propionates; Pyridoxal Phosphate; Substrate Specificity; Temperature | 1986 |
The effect of tryptophan metabolites on brain 5-hydroxytryptamine metabolism.
Topics: Alanine; Allopurinol; Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Carboxy-Lyases; Histamine; Kynurenic Acid; Kynurenine; Male; Methanol; Methyldopa; Mixed Function Oxygenases; Niacinamide; Nicotinic Acids; Nitroglycerin; ortho-Aminobenzoates; Phenylalanine; Phenylbutyrates; Picolinic Acids; Pyridines; Pyridoxal Phosphate; Pyridoxine; Rats; Serotonin; Sulfuric Acids; Time Factors; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1970 |
Model reactions which establish a facile reduction of pyridoxal phosphate and analogs by 1,4-dihydropyridines.
Topics: Alanine; Aldehydes; Cations, Divalent; Chemical Phenomena; Chemistry; Deuterium; Hydrogen; Hydrogen-Ion Concentration; Hydroquinones; Imines; Kinetics; Magnetic Resonance Spectroscopy; Methanol; Models, Chemical; Niacinamide; Oxidation-Reduction; Pyridines; Pyridoxal; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet | 1973 |
The metabolism of gamma-aminobutyric acid (GABA) in the lobster nervous system. I. GABA-glutamate transaminase.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Benzoates; Carbon Isotopes; Central Nervous System; Chlorides; Chromatography, Paper; Crustacea; Electrophoresis; Ethylmaleimide; Hydrogen-Ion Concentration; In Vitro Techniques; NAD; Pyridoxal Phosphate; Succinates; Transaminases | 1967 |
A modification of D-amino acid oxidase apoenzyme by pyridoxal 5'-phosphate.
Topics: Alanine; Animals; Boron Compounds; Chemical Phenomena; Chemistry; D-Amino-Acid Oxidase; Flavin-Adenine Dinucleotide; Kidney; Kinetics; Lysine; Pyridoxal Phosphate; Spectrophotometry; Swine | 1970 |
Substrate induced dimerization of D-amino-acid oxidase.
Topics: Alanine; Benzoates; Binding Sites; Chromatography, Gel; D-Amino-Acid Oxidase; Protein Conformation; Pyridoxal Phosphate | 1971 |
Synthesis of amino acids from succinate by the mitochondria of Neurospora crassa.
Topics: Adenosine Diphosphate; Alanine; Carbon Isotopes; Glucosephosphates; Glutamates; Malate Dehydrogenase; Mitochondria; NADP; Neurospora; Neurospora crassa; Phosphoric Monoester Hydrolases; Pyridoxal Phosphate; Pyruvates; Succinates; Thiamine Pyrophosphate; Valine | 1972 |
Ornithine degradation in Clostridium sticklandii; pyridoxal phosphate and coenzyme A dependent thiolytic cleavage of 2-amino-4-ketopentanoate to alanine and acetyl coenzyme A.
Topics: Acetyl Coenzyme A; Alanine; Amino Acids; Apoproteins; Carbon Radioisotopes; Catalysis; Chromatography, Paper; Clostridium; Coenzyme A; Cysteine; Electrophoresis, Paper; Enzyme Activation; Keto Acids; Ornithine; Pyridoxal Phosphate; Species Specificity; Structure-Activity Relationship; Sulfhydryl Reagents; Thiolester Hydrolases; Valerates | 1974 |
Biosynthesis of 4-thiouridylate. Participation of a sulfurtransferase containing pyridoxal 5'-phosphate.
Topics: Alanine; Aldehydes; Borohydrides; Chromatography; Cysteine; Enzyme Activation; Escherichia coli; Hydroxyapatites; Hydroxylamines; Kinetics; Organophosphorus Compounds; Picolines; Pyridoxal Phosphate; Pyruvates; RNA, Transfer; Serine; Sulfhydryl Compounds; Sulfur Isotopes; Sulfurtransferases; Thiouridine; Uridine | 1972 |
Regulation of biodegradative threonine deaminase. 3. Effects of beta substituents of substrate on absorption spectrum and circular dichroism of the enzyme-bound pyridoxal phosphate.
Topics: Alanine; Binding Sites; Chlorine; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Circular Dichroism; Escherichia coli; Hydro-Lyases; Hydroxylation; Kinetics; Molecular Conformation; Protein Binding; Pyridoxal Phosphate; Schiff Bases; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Stereoisomerism; Structure-Activity Relationship; Threonine; Time Factors; Valine | 1974 |
Evidence for induced fit of a pseudo-substrate of aspartate aminotransferase.
Topics: Alanine; Animals; Aspartate Aminotransferases; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Chlorine; Copper; Cytoplasm; Depression, Chemical; Formates; Glutamates; Kinetics; Myocardium; Pyridoxal Phosphate; Serine; Stimulation, Chemical; Sulfuric Acids; Swine | 1972 |
The stereochemistry of pyridoxal phosphate enzymes. The absolute stereochemistry of cofactor C' 4 protonation in the transamination of holoserine hydroxymethylase by D-alanine.
Topics: Alanine; Aldehydes; Amination; Amino Acids; Animals; Chemical Phenomena; Chemistry; Glycine; Isomerism; Liver; Phosphoric Acids; Protons; Pyridoxal Phosphate; Pyridoxamine; Pyruvates; Serine; Sheep; Tetrahydrofolates; Transaminases; Transferases; Tritium | 1973 |
Biosynthesis of branched-chain amino acids in Schizosaccharomyces pombe: regulatory properties of threonine deaminase.
Topics: Alanine; Amino Acids; Ammonium Sulfate; Ascomycota; Chromatography, Gel; Culture Media; Enzyme Activation; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Leucine; Protamines; Pyridoxal Phosphate; Stimulation, Chemical; Temperature; Threonine; Valine | 1973 |
Metabolism of omega-amino acids by rat tissues in vitro.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminocaproates; Aminoisobutyric Acids; Animals; Brain; Caprylates; Cyclohexanecarboxylic Acids; Glycine; Intestinal Mucosa; Kidney; Kinetics; Liver; Male; Methionine; Pyridoxal Phosphate; Rats; Schiff Bases; Spectrophotometry, Ultraviolet; Valerates; Valine | 1973 |
Interaction of tyrosine phenol-lyase with pyridoxal phosphate N-oxide and 2'-hydroxy pyridoxal phosphate.
Topics: Alanine; Apoproteins; Binding Sites; Cyclic N-Oxides; Escherichia; Lyases; Phenols; Protein Binding; Pyridoxal Phosphate; Spectrophotometry; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tyrosine | 1973 |
Affinity labeling of the active center of L-aspartate-beta-decarboxylase with beta-chloro-L-alanine.
Topics: Alanine; Alcaligenes; Aspartic Acid; Binding Sites; Binding, Competitive; Carbon Radioisotopes; Carboxy-Lyases; Chlorine; Cyanogen Bromide; Dialysis; Drug Stability; Glutamates; Hydrogen-Ion Concentration; Models, Chemical; Organophosphorus Compounds; Peptide Fragments; Phosphorus Radioisotopes; Pyridoxal Phosphate; Pyridoxamine; Pyruvates; Schiff Bases; Structure-Activity Relationship | 1974 |
Catalytic properties of 4'-substituted analogs of pyridoxal-5'-phosphate and pyridoxamine-5'-phosphate in the reaction of model and enzymatic transamination.
Topics: Alanine; Amines; Aspartate Aminotransferases; Binding Sites; Chemical Phenomena; Chemistry; Circular Dichroism; Electrophoresis; Isomerism; Ketoglutaric Acids; Kinetics; Magnetic Resonance Spectroscopy; Protein Binding; Pyridoxal Phosphate; Pyridoxamine; Schiff Bases; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1974 |
Tyrosine phenol lyase. I. Purification, crystallization, and properties.
Topics: Alanine; Amino Acids; Ammonia; Catechols; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Culture Media; Cysteine; Electrophoresis; Escherichia coli; Feedback; Kinetics; Lyases; Methods; Molecular Weight; Phenols; Protamines; Pyridoxal Phosphate; Pyruvates; Quaternary Ammonium Compounds; Serine; Stereoisomerism; Sulfates; Tyrosine; Ultracentrifugation | 1970 |
Tyrosine phenol lyase. II. Cofactor requrements.
Topics: Alanine; Amino Acids; Binding Sites; Boron Compounds; Chemical Phenomena; Chemistry; Chromatography, Paper; Dialysis; Electrophoresis; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lyases; Lysine; Phenols; Potassium; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Sodium; Spectrophotometry; Tyrosine; Ultraviolet Rays | 1970 |
Enzymatic formation of beta-cyanoalanine from cyanide.
Topics: Adenosine Triphosphate; Alanine; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Cyanides; Cysteine; Edetic Acid; Hydroxylamines; Indicators and Reagents; Isoniazid; Magnesium; Mercury; Plants; Pyridoxal Phosphate; Semicarbazides; Serine | 1965 |
[Threonine deaminease from Arthrobacter strain 23].
Topics: Alanine; Aminobutyrates; Aminoisobutyric Acids; Arthrobacter; Binding Sites; Bromides; Carbohydrates; Cell-Free System; Chemical Precipitation; Culture Media; Edetic Acid; Enzyme Activation; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Leucine; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Sulfates; Threonine; Ultracentrifugation; Valine; Vibration | 1971 |
Properties and subunit structure of the B component of Pseudomonas putida tryptophan synthetase.
Topics: Alanine; Amino Acids; Borohydrides; Carboxypeptidases; Catalysis; Chemical Precipitation; Chromatography, Gel; Cross Reactions; Detergents; Drug Stability; Electrophoresis, Disc; Escherichia coli; Formates; Glycerophosphates; Hot Temperature; Hydro-Lyases; Immune Sera; Immunodiffusion; Indoles; Kinetics; Macromolecular Substances; Mercaptoethanol; Molecular Weight; Oxidation-Reduction; Pseudomonas; Pyridoxal Phosphate; Serine; Spectrophotometry; Sulfuric Acids; Tryptophan; Ultracentrifugation; Urea | 1971 |
Studies in valine biosynthesis. IX. The enzymes in photosynthetic and autotrophic bacteria.
Topics: Aerobiosis; Alanine; Alcohols; Anaerobiosis; Bacteria; Carboxylic Acids; Chlorophyta; Chromatium; Glutamates; Glutamine; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Magnesium; Micrococcus; Models, Biological; Pseudomonas; Pyridoxal Phosphate; Rhodobacter sphaeroides; Rhodospirillum rubrum; Transaminases; Valine | 1971 |
Crystalline taurine: -ketoglutarate aminotransferase from Achromobacter superficialis.
Topics: Alanine; Alcaligenes; Aminoisobutyric Acids; Ammonium Sulfate; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Crystallization; Electrophoresis, Disc; Enzyme Activation; Hydrogen-Ion Concentration; Hydroxyapatites; Ketoglutaric Acids; Molecular Weight; Pyridoxal Phosphate; Pyridoxine; Spectrophotometry; Sulfonic Acids; Taurine; Transaminases; Ultracentrifugation; Ultraviolet Rays | 1972 |
The synthesis of taurine from sulfate. 3. Further evidence for the enzymatic pathway in chick liver.
Topics: Adenine Nucleotides; Alanine; Animals; Carbon Isotopes; Carboxy-Lyases; Chickens; Chromatography, Ion Exchange; L-Serine Dehydratase; Liver; Pyridoxal Phosphate; Serine; Sulfates; Sulfonic Acids; Sulfurtransferases; Taurine | 1972 |
Inactivation of bovine glutamate dehydrogenase by carbamyl phosphate and cyanate.
Topics: Alanine; Aldehydes; Amino Acids; Animals; Carbamates; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Cyanates; Glutamate Dehydrogenase; Kinetics; Lysine; Mathematics; Peptides; Phosphates; Picolines; Pyridoxal Phosphate; Trypsin | 1972 |
[Metabolic and catalytic functions of vitamin B6].
Topics: Alanine; Apoproteins; Catalysis; Chemical Phenomena; Chemistry; Enzyme Activation; Pyridoxal Phosphate; Pyridoxine; Tryptophan | 1972 |
Cystathionine -synthase. Studies of hydrogen exchange reactions.
Topics: Alanine; Aminobutyrates; Catalysis; Chemical Phenomena; Chemistry; Cystathionine; Cysteine; Deuterium; Homoserine; Kinetics; Lyases; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Salmonella; Serine; Succinates; Tritium | 1972 |
Specificity and some other properties of liver serine sulphhydrase: evidence for its identity with cystathionine -synthase.
Topics: Acetates; Alanine; Amino Acids; Animals; Catalysis; Chickens; Chlorine; Chromatography, Gel; Chromatography, Paper; Cycloserine; Cysteamine; Cysteine; Electrophoresis, Paper; Glycolates; Homocysteine; Hydro-Lyases; Hydroxylamines; Isoelectric Focusing; Kinetics; L-Serine Dehydratase; Liver; Mercaptoethanol; Nitriles; Penicillamine; Propionates; Pyridoxal Phosphate; Rats; Serine; Species Specificity; Sulfhydryl Compounds; Sulfides; Sulfuric Acids; Thioglycolates | 1971 |
Crystalline kynureninase from Pseudomonas marginalis.
Topics: Alanine; Ammonium Sulfate; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Crystallization; Electrophoresis, Disc; Hydrolases; Hydroxyapatites; Hydroxylamines; Kynurenine; Molecular Weight; Protein Binding; Pseudomonas; Pyridoxal Phosphate; Spectrophotometry; Ultracentrifugation | 1971 |
Inactivation of kynureninase by L-alanine.
Topics: Alanine; Borohydrides; Enzyme Activation; Hydrolases; Kinetics; Kynurenine; Oxidation-Reduction; Pseudomonas; Pyridoxal Phosphate; Sodium; Spectrophotometry | 1971 |
[Isolation and estimation of phosphopyridoxyllysine and pyridoxyllysine].
Topics: Alanine; Amino Acids; Aminocaproates; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis, Paper; Lysine; Methionine; Proteins; Pyridoxal Phosphate; Pyridoxine; Valine | 1971 |
Catalysis of transamination by acetate.
Topics: Acetates; Alanine; Catalysis; Chemical Phenomena; Chemistry; Copper; Pyridoxal Phosphate; Pyruvates | 1969 |
Studies on amino acid racemases. I. Partial purification and properties of the alanine racemase from Lactobacillus fermenti.
Topics: Acetates; Alanine; Aminobutyrates; Aspartic Acid; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Computers; Cysteine; Drug Stability; Glutamates; Glutathione; Hydrogen-Ion Concentration; Isomerases; Kinetics; Lactobacillus; Mercaptoethanol; Methods; Models, Biological; Models, Chemical; Pyridoxal Phosphate; Serine; Stereoisomerism; Temperature | 1969 |
Metabolism of glucose and glutamate by synaptosomes from mammalian cerebral cortex.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Carbon Isotopes; Centrifugation; Cerebral Cortex; Chromatography, Ion Exchange; Chromatography, Paper; Glucose; Glutamates; Glutamine; In Vitro Techniques; Lactates; Organoids; Oxygen Consumption; Potassium; Pyridoxal Phosphate; Rats; Synapses | 1969 |
Fluorometric determination of pyridoxal phosphate in enzymes.
Topics: Alanine; Alanine Transaminase; Aspartate Aminotransferases; Fluorometry; Glucosyltransferases; Isomerases; Methods; Pyridoxal Phosphate | 1969 |
Reaction of dithionite and bisulfite with pyridoxal and pyridoxal enzymes.
Topics: Alanine; Alanine Transaminase; Aspartate Aminotransferases; Chemical Phenomena; Chemistry; Cysteine; Enzymes; Isomerases; Pyridoxal Phosphate; Spectrophotometry; Sulfites | 1969 |
Racemization of D- or L-alanine by crystalline tyrosine phenol-lyase from Escherichia intermedia.
Topics: Alanine; Chemical Phenomena; Chemistry; Escherichia; Hydrogen-Ion Concentration; Kinetics; Lyases; Pyridoxal Phosphate; Spectrophotometry; Tyrosine | 1970 |
Equilibrium studies involving Schiff base complexes. The zinc(II)--pyridoxal phosphate-glycine and -alpha-alanine systems.
Topics: Alanine; Glycine; Imines; Pyridoxal Phosphate; Zinc | 1970 |
Control of pyridoxal phosphate enzyme reaction specificity studied with alpha-dialkylamino acid transaminase.
Topics: Acetaldehyde; Alanine; Amino Acids; Aminoisobutyric Acids; Binding Sites; Bromine; Carbon Isotopes; Chemical Phenomena; Chemistry; Cycloserine; Electrophoresis, Disc; Glyceraldehyde; Malonates; Models, Chemical; Pseudomonas; Pyridoxal Phosphate; Pyruvates; Quaternary Ammonium Compounds; Stereoisomerism; Transaminases | 1970 |
The thiol groups of rat liver cystathionase. Influence of pyridoxal phosphate, L-homoserine and L-alanine on the effect of p-chloromercuribenzoate and 5,5-dithiobis-(2-nitrobenzoate) on the enzyme.
Topics: Alanine; Animals; Benzoates; Chloromercuribenzoates; Hydro-Lyases; Liver; Nitro Compounds; Pyridoxal Phosphate; Rats; Sulfhydryl Compounds | 1971 |
Serine transhydroxymethylase. Affinity of the active site for substrates, substrate analogues, and anions.
Topics: Alanine; Aldehydes; Aminoisobutyric Acids; Animals; Benzoates; Binding Sites; Chlorides; Cysteamine; Cysteine; Electrophoresis; Folic Acid; Glycine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Models, Biological; Organophosphonates; Phosphates; Potassium; Propionates; Pyridoxal Phosphate; Rabbits; Serine; Spectrophotometry; Stereoisomerism; Sulfates; Sulfhydryl Compounds; Sulfonic Acids; Thermodynamics; Threonine; Transferases; Ultracentrifugation | 1971 |
Transsulfuration in higher plants. Partial purification and properties of beta-cystathionase of spinach.
Topics: Alanine; Amino Acids; Benzoates; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Cysteine; Drug Stability; Edible Grain; Ethylmaleimide; Homocysteine; Hydro-Lyases; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; Models, Structural; Plants; Pyridoxal Phosphate; Pyruvates; Quaternary Ammonium Compounds; Serine; Species Specificity; Spectrophotometry; Stereoisomerism; Sulfates; Sulfides; Sulfur; Triticum | 1971 |
Mechanism of inhibition of spinach beta-cystathionase by rhizobitoxine.
Topics: Alanine; Amino Acids; Antitoxins; Binding Sites; Chromatography, Gel; Cystine; Dialysis; Hydro-Lyases; Kinetics; Mathematics; Nitriles; Plants; Pyridoxal Phosphate; Rhizobium; Spectrophotometry; Sulfides; Sulfur; Time Factors; Toxins, Biological | 1971 |
Arginine racemase of Pseudomonas graveolens. II. Racemization and transamination of ornithine catalyzed by arginine racemase.
Topics: Acetates; Alanine; Amino Acids; Aminobutyrates; Arginine; Catalysis; Dialysis; Electrophoresis; Enzyme Activation; Hydrogen-Ion Concentration; Isomerases; Keto Acids; Ketoglutaric Acids; Kinetics; Light; Models, Biological; Organophosphorus Compounds; Ornithine; Oxaloacetates; Paper; Phenylpyruvic Acids; Picolines; Propionates; Protein Binding; Pseudomonas; Pyridoxal Phosphate; Pyruvates; Rotation; Spectrophotometry; Stereoisomerism; Transaminases; Ultraviolet Rays | 1971 |
Coenzyme content of purified alanine racemase from Pseudomonas.
Topics: Alanine; Biological Assay; Electrophoresis; Flavins; Fluorescence; Isomerases; Pseudomonas; Pyridoxal Phosphate; Saccharomyces; Spectrum Analysis; Stereoisomerism; Ultraviolet Rays | 1969 |
The effects of various vitamin B6 5'-phosphate derivatives on the structure and activities of L-aspartate beta-decarboxylase.
Topics: Alanine; Alcaligenes; Amines; Aspartic Acid; Binding Sites; Carbon Isotopes; Carboxy-Lyases; Chemical Phenomena; Chemistry; Cysteine; Dialysis; Electrophoresis; Fluorometry; Hydrolases; Kinetics; Models, Chemical; Molecular Weight; Pyridoxal Phosphate; Pyridoxine; Pyruvates; Spectrum Analysis; Sulfur; Transaminases | 1969 |
Crystalline amino acid racemase with low substrate specificity.
Topics: Alanine; Amino Acids; Arginine; Butyrates; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Dialysis; Electrophoresis, Disc; Ethionine; Isomerases; Leucine; Lysine; Methionine; Methods; Molecular Weight; Pseudomonas; Pyridoxal Phosphate; Spectrophotometry; Ultracentrifugation | 1969 |
Aminotransferase activity of Hartmannella (Culbertson strain A-1) grown axenically.
Topics: Alanine; Alanine Transaminase; Amebicides; Amoeba; Animals; Anti-Bacterial Agents; Chelating Agents; Chloromercuribenzoates; Chromatography, Paper; Coenzymes; Cyanides; Dicarboxylic Acids; Glutarates; Hydrogen-Ion Concentration; Pyridoxal Phosphate | 1969 |
D-Alanine-D-glutamate transaminase. II. Inhibitors and the mechanism of transamination of D-amino acids.
Topics: Alanine; Cyanides; Cycloserine; Enzymes; Glutamates; Hydroxylamines; Ketoglutaric Acids; Kinetics; Pyridoxal Phosphate; Pyruvates; Spectrum Analysis; Transaminases | 1965 |
The utilization of tryptophan by neurospora.
Topics: Alanine; In Vitro Techniques; Indoles; Mutation; Neurospora; ortho-Aminobenzoates; Pyridoxal Phosphate; Pyruvates; Temperature; Tryptophan | 1965 |
Further studies of the antimycobacterial agents glycyl hydroxamic acid and beta-alanyl hydroxamic acid.
Topics: Alanine; Animals; Anti-Bacterial Agents; Ascorbic Acid; Chemical Phenomena; Chemistry; Dopa Decarboxylase; Enzymes; Guinea Pigs; Hydroxylamines; Mycobacterium; Pyridoxal Phosphate; Spectrum Analysis | 1966 |
Synthesis and properties of some N-pyridoxyl-L-amino acids and N-(5-phosphopyridoxyl)-L-amino acids.
Topics: Alanine; Aldehydes; Arginine; Aspartic Acid; Chemistry, Organic; Chromatography, Paper; Glutamates; Organic Chemistry Phenomena; Pyridines; Pyridoxal Phosphate; Pyrrolidinones; Serine; Tryptophan; Tyrosine | 1967 |
Free amino acids and glutamate decarboxylase activity in brain of mice during drug-induced convulsions.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Brain Chemistry; Carboxy-Lyases; Glutamates; Glutamine; Hydrazines; Insulin; Methionine; Methionine Sulfoximine; Mice; Pentylenetetrazole; Pyridoxal Phosphate; Seizures; Thiosemicarbazones; Transaminases | 1967 |
Beta-cyanoalanine, an inhibitor of rat liver cystathionase.
Topics: Alanine; Amino Acids; Animals; Cyanides; Hydro-Lyases; Hydroxybutyrates; Liver; Nitriles; Penicillamine; Plants; Pyridoxal Phosphate; Rats; Semicarbazides; Toxins, Biological | 1967 |
Conversion of glucose to neurotransmitter amino acids in the brains of young and aging rats.
Topics: Age Factors; Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Female; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamine; Neurotransmitter Agents; Pyridoxal Phosphate; Rats | 1980 |
Ox liver glutamate dehydrogenase. The use of chemical modification to study the relationship between catalytic sites for different amino acid substrates and the question of kinetic non-equivalence of the subunits.
Topics: Alanine; Amino Acids; Animals; Binding Sites; Cattle; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Kinetics; Leucine; Liver; Pyridoxal Phosphate | 1984 |
Interactions of tryptophan synthase, tryptophanase, and pyridoxal phosphate with oxindolyl-L-alanine and 2,3-dihydro-L-tryptophan: support for an indolenine intermediate in tryptophan metabolism.
Topics: Alanine; Binding, Competitive; Chemical Phenomena; Chemistry; Escherichia coli; Kinetics; Lyases; Mass Spectrometry; Oxindoles; Pyridoxal Phosphate; Spectrophotometry; Tryptophan; Tryptophan Synthase; Tryptophanase | 1984 |
Catalytic properties of the active site of alanine racemase from B. subtilis.
Topics: Alanine; Alanine Racemase; Amino Acid Isomerases; Bacillus subtilis; beta-Alanine; Binding Sites; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Molecular Weight; Pyridoxal Phosphate | 1984 |
3-Chloro-D-alanine chloride-lyase (deaminating) of Pseudomonas putida CR 1-1.
Topics: Alanine; beta-Alanine; Chemical Phenomena; Chemistry; Crystallization; Hydrogen-Ion Concentration; Isoelectric Point; Kinetics; Lyases; Molecular Weight; Pseudomonas; Pyridoxal Phosphate | 1984 |
Inactivation of the Pseudomonas striata broad specificity amino acid racemase by D and L isomers of beta-substituted alanines: kinetics, stoichiometry, active site peptide, and mechanistic studies.
Topics: Alanine; Amino Acid Isomerases; Amino Acids; beta-Alanine; Binding Sites; Borates; Isomerism; Kinetics; Molecular Weight; NAD; Pseudomonas; Pyridoxal Phosphate; Serine; Trypsin | 1984 |
3-Chloro-D-alanine chloride-lyase (deaminating) of Pseudomonas putida CR 1.1. Purification and characterization of a novel enzyme occurring in 3-chloro-D-alanine-resistant pseudomonads.
Topics: Alanine; Bacteria; beta-Alanine; Crystallization; Drug Resistance, Microbial; Enzyme Induction; Kinetics; Lyases; Macromolecular Substances; Molecular Weight; Pseudomonas; Pyridoxal Phosphate; Species Specificity | 1982 |
Equilibrium and kinetic study of interaction of amino acid inhibitors with tryptophanase: mechanism of quinonoid formation.
Topics: Alanine; Deuterium; Escherichia coli; Ethionine; Hydrogen-Ion Concentration; Kinetics; Lyases; Protein Binding; Pyridoxal Phosphate; Quinones; Spectrophotometry; Tryptophanase | 1981 |
International federation of clinical chemistry. Scientific committee. Expert panel on enzymes. IFCC document stage 2, draft 1; 1979-11-19 with a view to an IFCC recommendation. IFCC methods for the measurement of catalytic concentration of enzymes. Part 3
Topics: Alanine; Alanine Transaminase; Drug Stability; Humans; Hydrogen-Ion Concentration; Ketoglutaric Acids; L-Lactate Dehydrogenase; Mathematics; Methods; Pyridoxal Phosphate; Specimen Handling; Spectrophotometry, Ultraviolet; Time Factors | 1980 |
Role of leucine 201 of thermostable D-amino acid aminotransferase from a thermophile, Bacillus sp. YM-1.
Topics: Alanine; Alanine Transaminase; Bacillus; Bacterial Proteins; Base Sequence; Binding Sites; Catalysis; Circular Dichroism; D-Alanine Transaminase; Enzyme Activation; Enzyme Stability; Hot Temperature; Kinetics; Leucine; Molecular Sequence Data; Mutation; Pyridoxal Phosphate; Pyridoxamine; Spectrometry, Fluorescence; Tryptophan | 1995 |
The interaction of glutamate decarboxylase from Escherichia coli with substrate analogues modified at C-3 and C-4.
Topics: Alanine; Decarboxylation; Escherichia coli; Glutamate Decarboxylase; Glutamic Acid; Kinetics; Pyridoxal Phosphate; Spectrophotometry; Structure-Activity Relationship; Substrate Specificity | 1995 |
Tryptophanase from Escherichia coli: catalytic and spectral properties in water-organic solvents.
Topics: Alanine; Catalysis; Cysteine; Dimethylformamide; Escherichia coli; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Methanol; Pyridoxal Phosphate; Solutions; Spectrophotometry, Ultraviolet; Stereoisomerism; Substrate Specificity; Tryptophan; Tryptophanase; Water | 1994 |
NMR studies of 1H resonances in the 10-18-ppm range for aspartate aminotransferase from Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Asparagine; Aspartate Aminotransferases; Escherichia coli; Histidine; Hydrogen; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins; Sensitivity and Specificity; Tryptophan | 1994 |
Comparison of L-aspartate 4-carboxy-lyases of Cunninghamella elegans and Penicillium citrinum.
Topics: Alanine; Carboxy-Lyases; Decarboxylation; Edetic Acid; Enzyme Activation; Glutathione; Hydrogen-Ion Concentration; Iodoacetates; Iodoacetic Acid; Keto Acids; Kinetics; Mercaptoethanol; Metals; Mucorales; Penicillium; Pyridoxal Phosphate; Temperature | 1994 |
Intersubunit location of the active site of mammalian ornithine decarboxylase as determined by hybridization of site-directed mutants.
Topics: Alanine; Animals; Base Sequence; Binding Sites; Cysteine; Eflornithine; Lysine; Macromolecular Substances; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Hybridization; Ornithine Decarboxylase; Pyridoxal Phosphate; Structure-Activity Relationship | 1993 |
Catalytic ability and stability of two recombinant mutants of D-amino acid transaminase involved in coenzyme binding.
Topics: Alanine; Base Sequence; beta-Alanine; Binding Sites; Catalysis; D-Alanine Transaminase; Enzyme Inhibitors; Enzyme Stability; Guanidine; Guanidines; Hot Temperature; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Denaturation; Pyridoxal Phosphate; Recombinant Proteins; Spectrophotometry; Structure-Activity Relationship; Substrate Specificity; Sulfhydryl Compounds; Transaminases; Urea | 1995 |
Inactivation of gamma-aminobutyric acid aminotransferase by L-3-chloroalanine hydroxamate.
Topics: 4-Aminobutyrate Transaminase; Alanine; Animals; Buffers; Cyclohexanecarboxylic Acids; Cycloserine; Deuterium; Prodrugs; Pyridoxal Phosphate; Swine; Time Factors | 1995 |
Mechanistic studies on the 8-amino-7-oxopelargonate synthase, a pyridoxal-5'-phosphate-dependent enzyme involved in biotin biosynthesis.
Topics: Acyl Coenzyme A; Acyltransferases; Alanine; Bacillus; Biotin; Models, Chemical; Pyridoxal Phosphate; Recombinant Proteins | 1996 |
Escherichia coli contains a protein that is homologous in function and N-terminal sequence to the protein encoded by the nifS gene of Azotobacter vinelandii and that can participate in the synthesis of the Fe-S cluster of dihydroxy-acid dehydratase.
Topics: Alanine; Amino Acid Sequence; Azotobacter vinelandii; Bacterial Proteins; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Disulfides; Escherichia coli; Genes, Bacterial; Haemophilus influenzae; Hydro-Lyases; Iron-Sulfur Proteins; Kinetics; Macromolecular Substances; Molecular Sequence Data; Naphthalenesulfonates; Pantetheine; Peptide Fragments; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Sulfhydryl Reagents | 1996 |
Substitution of pyridoxal 5'-phosphate in the O-acetylserine sulfhydrylase from Salmonella typhimurium by cofactor analogs provides a test of the mechanism proposed for formation of the alpha-aminoacrylate intermediate.
Topics: Alanine; Circular Dichroism; Cysteine Synthase; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Pyridoxal Phosphate; Salmonella typhimurium; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1996 |
Crystal structure of the pyridoxal-5'-phosphate dependent cystathionine beta-lyase from Escherichia coli at 1.83 A.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Escherichia coli; Lyases; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Pyridoxal Phosphate; Sequence Homology, Amino Acid | 1996 |
A change in the internal aldimine lysine (K42) in O-acetylserine sulfhydrylase to alanine indicates its importance in transimination and as a general base catalyst.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Catalysis; Cysteine Synthase; DNA Primers; Escherichia coli; Imines; Kinetics; Lysine; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Recombinant Proteins; Salmonella typhimurium; Schiff Bases; Spectrophotometry | 1996 |
Substitutions of alanine for cysteine at a reactive thiol site and for lysine at a pyridoxal phosphate binding site of 1-aminocyclopropane-1-carboxylate deaminase.
Topics: Absorption; Alanine; Base Sequence; Binding Sites; Carbon-Carbon Lyases; Catalysis; Cysteine; Escherichia coli; Gene Expression Regulation, Enzymologic; Lyases; Lysine; Mutagenesis, Site-Directed; Mutation; Plasmids; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Substrate Specificity; Sulfhydryl Compounds; Valine | 1997 |
Mutation of cysteine 111 in Dopa decarboxylase leads to active site perturbation.
Topics: 5-Hydroxytryptophan; Alanine; Animals; Base Sequence; Binding Sites; Circular Dichroism; Cysteine; Dopa Decarboxylase; Hydrogen-Ion Concentration; Kidney; Kinetics; Levodopa; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Serine; Spectrometry, Fluorescence; Spectrophotometry; Structure-Activity Relationship; Swine | 1997 |
Arginine294 is essential for the inhibition of Anabaena PCC 7120 ADP-glucose pyrophosphorylase by phosphate.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Substitution; Anabaena; Arginine; Binding Sites; Fructosediphosphates; Glucose-1-Phosphate Adenylyltransferase; Glyceric Acids; Kinetics; Mutagenesis, Site-Directed; Nucleotidyltransferases; Phenylglyoxal; Phosphates; Pyridoxal Phosphate; Recombinant Proteins | 1997 |
Substrate inhibition of D-amino acid transaminase and protection by salts and by reduced nicotinamide adenine dinucleotide: isolation and initial characterization of a pyridoxo intermediate related to inactivation.
Topics: Alanine; Catalysis; Chromatography, High Pressure Liquid; D-Alanine Transaminase; Enzyme Inhibitors; NAD; Pyridoxal Phosphate; Pyridoxamine; Pyruvic Acid; Salts; Serine; Transaminases | 1998 |
Tryptophan synthase mutations that alter cofactor chemistry lead to mechanism-based inactivation.
Topics: Alanine; Aspartic Acid; Bacterial Proteins; Catalysis; Circular Dichroism; Enzyme Activation; Multienzyme Complexes; Mutagenesis, Site-Directed; Peptide Fragments; Pyridoxal Phosphate; Serine; Spectrometry, Fluorescence; Substrate Specificity; Tryptophan Synthase | 1998 |
The imine-pyridine torsion of the pyridoxal 5'-phosphate Schiff base of aspartate aminotransferase lowers its pKa in the unliganded enzyme and is crucial for the successive increase in the pKa during catalysis.
Topics: Alanine; Aspartate Aminotransferases; Binding Sites; Catalysis; Energy Transfer; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Ligands; Lysine; N-Methylaspartate; Protein Conformation; Protons; Pyridines; Pyridoxal Phosphate; Schiff Bases; Spectrophotometry; Thermodynamics | 1998 |
Restoration of rat liver L-threonine dehydratase activity by pyridoxamine 5'-phosphate: the half-transaminating activity of L-threonine dehydratase and its regulatory role.
Topics: Acetoacetates; Alanine; Animals; Apoenzymes; Enzyme Reactivators; Liver; Male; Pyridoxal Phosphate; Pyridoxamine; Pyruvic Acid; Rats; Rats, Wistar; Threonine Dehydratase | 1998 |
The crystal structure of 8-amino-7-oxononanoate synthase: a bacterial PLP-dependent, acyl-CoA-condensing enzyme.
Topics: Acyl Coenzyme A; Acyltransferases; Alanine; Amino Acid Sequence; Apoenzymes; Bacterial Proteins; Biotin; Catalytic Domain; Coenzyme A-Transferases; Crystallography, X-Ray; Dimerization; Enzyme Stability; Escherichia coli; Evolution, Molecular; Holoenzymes; Models, Molecular; Molecular Sequence Data; Protein Conformation; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Static Electricity | 1998 |
Slow-binding and competitive inhibition of 8-amino-7-oxopelargonate synthase, a pyridoxal-5'-phosphate-dependent enzyme involved in biotin biosynthesis, by substrate and intermediate analogs. Kinetic and binding studies.
Topics: Acyl Coenzyme A; Acyltransferases; Alanine; Aldehydes; Aminoethylphosphonic Acid; Biotin; Catalytic Domain; Dose-Response Relationship, Drug; Imines; Kinetics; Models, Chemical; Organophosphonates; Protein Conformation; Pyridoxal Phosphate; Stereoisomerism | 1999 |
Role of lysine 39 of alanine racemase from Bacillus stearothermophilus that binds pyridoxal 5'-phosphate. Chemical rescue studies of Lys39 --> Ala mutant.
Topics: Alanine; Alanine Racemase; Amino Acid Substitution; Catalysis; Circular Dichroism; Geobacillus stearothermophilus; Lysine; Models, Chemical; Mutagenesis, Site-Directed; Protein Conformation; Pyridoxal Phosphate; Structure-Activity Relationship | 1999 |
Catalytic mechanism of the tryptophan synthase alpha(2)beta(2) complex. Effects of pH, isotopic substitution, and allosteric ligands.
Topics: Alanine; Allosteric Regulation; Catalytic Domain; Deuterium; Glycine; Hydrogen-Ion Concentration; Indoles; Ligands; Models, Chemical; Oxindoles; Pyridoxal Phosphate; Salmonella typhimurium; Serine; Tryptophan Synthase | 1999 |
Crystal structures of dialkylglycine decarboxylase inhibitor complexes.
Topics: Alanine; Amino Acids; Amino Acids, Cyclic; Carboxy-Lyases; Crystallography, X-Ray; Cycloserine; Ligands; Models, Molecular; Potassium; Pyridines; Pyridoxal Phosphate | 1999 |
The role of Glu74 and Tyr82 in the reaction catalyzed by sheep liver cytosolic serine hydroxymethyltransferase.
Topics: Alanine; Amino Acid Substitution; Animals; Apoenzymes; Binding Sites; Calorimetry, Differential Scanning; Catalysis; Cytosol; Formaldehyde; Glutamic Acid; Glycine Hydroxymethyltransferase; Humans; Kinetics; Liver; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Rabbits; Recombinant Fusion Proteins; Serine; Sheep; Structure-Activity Relationship; Tetrahydrofolates; Tyrosine | 2000 |
Stereochemistry of the transamination reaction catalyzed by aminodeoxychorismate lyase from Escherichia coli: close relationship between fold type and stereochemistry.
Topics: Alanine; Apoenzymes; Catalysis; Escherichia coli; Evolution, Molecular; Hydrogen; Kinetics; Molecular Conformation; Oxo-Acid-Lyases; Protein Folding; Pyridoxal Phosphate; Pyridoxamine; Pyruvic Acid; Recombinant Proteins; Spectrophotometry; Transaminases; Tryptophan Synthase; Tryptophanase | 2000 |
Rapid kinetic and isotopic studies on dialkylglycine decarboxylase.
Topics: Alanine; Aminoisobutyric Acids; Carbon Isotopes; Carboxy-Lyases; Decarboxylation; Deuterium; Enzyme Activation; Isoenzymes; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Protons; Pyridoxal Phosphate; Pyruvic Acid; Transaminases | 2001 |
Occurrence of D-Amino Acids and a pyridoxal 5'-phosphate-dependent aspartate racemase in the acidothermophilic archaeon, Thermoplasma acidophilum.
Topics: Alanine; Amino Acid Isomerases; Amino Acids; Aspartic Acid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethylmaleimide; Glutamic Acid; Leucine; Lysine; Phenylalanine; Pyridoxal Phosphate; Stereoisomerism; Thermoplasma | 2001 |
Inhibitory effect of glycation on catalytic activity of alanine aminotransferase.
Topics: Alanine; Alanine Transaminase; Animals; Catalysis; Enzyme Activation; Fructose; Glucose; Glyceraldehyde; In Vitro Techniques; Ketoglutaric Acids; Lysine; Myocardium; Pharmacology; Pyridoxal Phosphate; Ribose; Swine; Time Factors | 2001 |
Metal ion inhibition of nonenzymatic pyridoxal phosphate catalyzed decarboxylation and transamination.
Topics: Alanine; Aluminum; Amination; Aminoisobutyric Acids; Carboxy-Lyases; Catalysis; Cations; Decarboxylation; Ethylamines; Kinetics; Pyridoxal Phosphate | 2001 |
Characterization of the S272A,D site-directed mutations of O-acetylserine sulfhydrylase: involvement of the pyridine ring in the alpha,beta-elimination reaction.
Topics: Alanine; Aspartic Acid; Binding Sites; Catalysis; Circular Dichroism; Cysteine Synthase; Deuterium; Hydrogen Bonding; Kinetics; Mutagenesis, Site-Directed; Pyridines; Pyridoxal Phosphate; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity | 2003 |
CONVULSANT EFFECT OF L-GLUTAMIC ACID-GAMMA-HYDRAZIDE BY SIMULTANEOUS TREATMENT WITH PYRIDOXAL PHOSPHATE.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Brain; Carboxy-Lyases; Convulsants; Glutamates; Glutamine; Hydrazines; Mice; Pharmacology; Proteins; Pyridoxal Phosphate; Research; Seizures; Toxicology | 1964 |
IN VITRO EFFECT OF ADRENAL STEROIDS ON CARBOHYDRATE SYNTHESIS IN LIVER OF PYRIDOXINE-DEFICIENT RATS.
Topics: Alanine; Alanine Transaminase; Carbohydrate Metabolism; In Vitro Techniques; Liver; Liver Glycogen; Pharmacology; Pyridoxal Phosphate; Pyridoxine; Rats; Research; Steroids; Triamcinolone; Vitamin B 6 Deficiency | 1964 |
RESPONSE OF 1-ASPARTIC-4-CARBOXYLASE TO SELECTED INHIBITORS.
Topics: Alanine; Aspartic Acid; Carbon Dioxide; Carboxy-Lyases; Enzyme Inhibitors; Flavobacterium; Keto Acids; Ketoglutaric Acids; Mitomycin; Mitomycins; Penicillins; Proteins; Pyridoxal Phosphate; Pyruvates; Research; Serine; Vancomycin | 1964 |
PURIFICATION AND PROPERTIES OF THE ALANINE RACEMASE FROM BACILLUS SUBTILIS.
Topics: Alanine; Alanine Racemase; Amino Acid Oxidoreductases; Animals; Bacillus subtilis; Cattle; D-Amino-Acid Oxidase; Dialysis; Edetic Acid; Electrophoresis; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Glutathione; Hot Temperature; Isomerases; Mercury; NAD; NADP; Oxidoreductases; Pharmacology; Pyridoxal Phosphate; Renal Dialysis; Research; Serum Albumin; Serum Albumin, Bovine; Streptomycin | 1964 |
ENZYMATIC DESULFINATION OF CYSTEINE SULFINIC ACID.
Topics: Alanine; Alcaligenes; Aspartic Acid; Biochemical Phenomena; Biochemistry; Carboxy-Lyases; Cysteine; Keto Acids; Ketoglutaric Acids; Pyridoxal Phosphate; Research; Sulfites | 1964 |
BACTERIAL METABOLISM OF 2-METHYLALANINE.
Topics: Acetone; Alanine; Amines; Amino Acids; Aminoisobutyric Acids; Carbon Dioxide; Manometry; Pyridoxal Phosphate; Pyruvates; Renal Dialysis; Research; Soil Microbiology | 1964 |
RELATIONSHIP OF A BETA-ALANINE-PYRUVIC AMINOTRANSFERASE TO REVERSAL OF D-SERINE INHIBITION OF GROWTH.
Topics: Alanine; Alanine Transaminase; Aspartic Acid; beta-Alanine; Cycloserine; Flavobacterium; Ketoglutaric Acids; Mitomycin; Mitomycins; Pantothenic Acid; Penicillins; Pharmacology; Pyridoxal Phosphate; Pyruvates; Research; Serine; Transaminases; Vancomycin | 1964 |
SERINE TRANSHYDROXYMETHYLASE. TRANSAMINATION OF D-ALANINE.
Topics: Alanine; Animals; Glycine Hydroxymethyltransferase; Hydrogen-Ion Concentration; Liver; Pyridoxal Phosphate; Rabbits; Research; Spectrophotometry; Transferases | 1964 |
ACTION OF CYCLOSERINE ON A SPECIES OF ERWINIA WITH REFERENCE TO CELL DIVISION.
Topics: Alanine; Calcium; Cell Division; Culture Media; Cycloserine; Enzyme Inhibitors; Erwinia; Hydrogen-Ion Concentration; Lactones; Manganese; Metabolism; Pharmacology; Pyridoxal Phosphate; Research | 1965 |
Assessment of vitamin B-6 estimated average requirement and recommended dietary allowance for adolescents aged 13-15 years using vitamin B-6 intake, nutritional status and anthropometry.
Topics: Adolescent; Alanine; Anthropometry; Aspartate Aminotransferases; Diet; Erythrocytes; Female; Humans; Male; Nutrition Policy; Nutritional Requirements; Nutritional Status; Pyridoxal Phosphate; Pyridoxic Acid; Taiwan; Vitamin B 6 | 2003 |
G-1:C73 recognition by an arginine cluster in the active site of Escherichia coli histidyl-tRNA synthetase.
Topics: Acylation; Alanine; Arginine; Base Pairing; Binding Sites; Computer Simulation; Cytosine; Escherichia coli Proteins; Guanine; Histidine; Histidine-tRNA Ligase; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Pyridoxal Phosphate; RNA, Transfer, His; Substrate Specificity | 2004 |
Three-dimensional structure of kynureninase from Pseudomonas fluorescens.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Binding Sites; Crystallization; Crystallography, X-Ray; Glutamic Acid; Humans; Hydrolases; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Folding; Pseudomonas fluorescens; Pyridoxal Phosphate; Sequence Alignment; Sequence Homology, Amino Acid | 2004 |
Identification of functionally important residues in the pyridoxal-5'-phosphate-dependent catalytic antibody 15A9.
Topics: Alanine; Amino Acid Sequence; Antibodies, Catalytic; Binding Sites, Antibody; Haptens; Immunoglobulin Variable Region; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins | 2004 |
Claisen-type addition of glycine to pyridoxal in water.
Topics: Alanine; Glycine; Pyridoxal Phosphate; Water | 2004 |
Multiple active site conformations revealed by distant site mutation in ornithine decarboxylase.
Topics: Alanine; Animals; Binding Sites; Crystallization; Crystallography, X-Ray; Diamines; Dimerization; Kinetics; Lysine; Mutagenesis, Site-Directed; Ornithine; Ornithine Decarboxylase; Protein Conformation; Putrescine; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Trypanosoma brucei brucei | 2004 |
Role of lysine-256 in Citrobacter freundii tyrosine phenol-lyase in monovalent cation activation.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cations, Monovalent; Citrobacter freundii; Enzyme Activation; Glutamic Acid; Histidine; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Potassium; Protein Binding; Pyridoxal Phosphate; Rabbits; Spectrophotometry; Tyrosine Phenol-Lyase | 2004 |
Structure of a pseudomerohedrally twinned monoclinic crystal form of a pyridoxal phosphate-dependent catalytic antibody.
Topics: Alanine; Antibodies, Catalytic; Binding Sites, Antibody; Crystallography, X-Ray; Dimerization; Iodides; Models, Molecular; Pyridoxal Phosphate | 2005 |
Molecular and biochemical characterization of a serine racemase from Arabidopsis thaliana.
Topics: Alanine; Arabidopsis; Arginine; Catalysis; Cations, Divalent; Dimerization; Escherichia coli; Glutamine; Hydro-Lyases; Hydrogen-Ion Concentration; In Situ Hybridization, Fluorescence; Metals; Molecular Sequence Data; Pyridoxal Phosphate; Racemases and Epimerases; Sequence Homology, Amino Acid; Serine; Stereoisomerism; Substrate Specificity | 2006 |
Transition state stabilization and alpha-amino carbon acidity in alanine racemase.
Topics: Alanine; Alanine Racemase; Binding Sites; Catalysis; Computer Simulation; Hydrogen Bonding; Hydrogen-Ion Concentration; Molecular Structure; Protons; Pyridoxal Phosphate; Solvents; Stereoisomerism | 2006 |
Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase.
Topics: Aedes; Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Kynurenine; Models, Molecular; Molecular Sequence Data; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Substrate Specificity; Transaminases; Xanthurenates | 2006 |
Alanine racemase from the green alga Chlamydomonas reinhardtii.
Topics: Alanine; Alanine Racemase; Algal Proteins; Animals; Chlamydomonas reinhardtii; Coenzymes; Protozoan Proteins; Pyridoxal Phosphate | 2007 |
Histidine 282 in 5-aminolevulinate synthase affects substrate binding and catalysis.
Topics: 5-Aminolevulinate Synthetase; Alanine; Animals; Catalysis; Crystallography, X-Ray; Glycine; Histidine; Kinetics; Mice; Mutagenesis, Site-Directed; Protein Binding; Pyridoxal Phosphate; Rhodobacter capsulatus; Spectrophotometry; Substrate Specificity | 2007 |
Synthesis of beta-hydroxy-alpha-amino acids with a reengineered alanine racemase.
Topics: Alanine; Alanine Racemase; Aldehydes; Amino Acids; Bacteria; Catalysis; Combinatorial Chemistry Techniques; Glycine; Glycine Hydroxymethyltransferase; Molecular Structure; Protein Engineering; Pyridoxal Phosphate; Stereoisomerism | 2008 |
Modulation of cystathionine beta-synthase activity by the Arg-51 and Arg-224 mutations.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Catalysis; Cystathionine; Cystathionine beta-Synthase; Heme; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutation; Protein Structure, Secondary; Protein Structure, Tertiary; Pyridoxal Phosphate; Recombinant Proteins | 2008 |
Characterization of endogenous pyridoxal 5'-phosphate-dependent alanine racemase from Bacillus pseudofirmus OF4.
Topics: Alanine; Alanine Racemase; Amino Acid Sequence; Bacillus; Bacterial Proteins; Cloning, Molecular; Hydrogen-Ion Concentration; Molecular Sequence Data; Pyridoxal Phosphate; Substrate Specificity; Temperature | 2009 |
Multiple roles of the active site lysine of Dopa decarboxylase.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alanine; Amino Acid Substitution; Ammonia; Animals; Binding Sites; Catalysis; Deamination; Decarboxylation; Dopa Decarboxylase; Dopamine; Hydrogen Bonding; Hydrolysis; Kidney; Kinetics; Levodopa; Lysine; Models, Chemical; Molecular Structure; Oxidation-Reduction; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Structure-Activity Relationship; Swine | 2009 |
Assay of alanine:glyoxylate aminotransferase in human liver by its serine: glyoxylate aminotransferase activity.
Topics: Alanine; Animals; Biological Assay; Humans; Liver; Pyridoxal Phosphate; Serine; Tissue Extracts; Transaminases | 2009 |
Structural analysis of WbpE from Pseudomonas aeruginosa PAO1: a nucleotide sugar aminotransferase involved in O-antigen assembly.
Topics: Alanine; Crystallography, X-Ray; Models, Molecular; Mutation; Nitrogenous Group Transferases; O Antigens; Protein Binding; Pseudomonas aeruginosa; Pseudomonas Infections; Pyridoxal Phosphate; Pyridoxamine; Schiff Bases; Uridine Diphosphate Glucuronic Acid | 2010 |
Necessary and sufficient conditions for the asymmetric synthesis of chiral amines using ω-aminotransferases.
Topics: Acetophenones; Agrobacterium tumefaciens; Alanine; Amines; Isomerism; L-Lactate Dehydrogenase; Molecular Conformation; Pyridoxal Phosphate; Pyridoxamine; Streptomyces; Transaminases; Vibrio | 2011 |
Crystal structure of the S187F variant of human liver alanine: glyoxylate [corrected] aminotransferase associated with primary hyperoxaluria type I and its functional implications.
Topics: Alanine; Catalytic Domain; Crystallography, X-Ray; Humans; Hyperoxaluria, Primary; Liver; Models, Molecular; Point Mutation; Protein Conformation; Pyridoxal Phosphate; Transaminases | 2013 |
Vitamin B-6 restriction reduces the production of hydrogen sulfide and its biomarkers by the transsulfuration pathway in cultured human hepatoma cells.
Topics: Alanine; Biomarkers; Carcinoma, Hepatocellular; Cysteine; Hep G2 Cells; Homocysteine; Humans; Hydrogen Sulfide; Linear Models; Liver Neoplasms; Pyridoxal Phosphate; Sulfides; Vitamin B 6; Vitamin B 6 Deficiency | 2014 |
Pre-steady-state kinetic and structural analysis of interaction of methionine γ-lyase from Citrobacter freundii with inhibitors.
Topics: Alanine; Bacterial Proteins; Carbon-Sulfur Lyases; Catalytic Domain; Citrobacter freundii; Crystallography, X-Ray; Cycloserine; Cysteine; Enzyme Inhibitors; Escherichia coli; Gene Expression; Glycine; Imines; Kinetics; Models, Chemical; Pyridoxal Phosphate; Recombinant Proteins; Thermodynamics; Valine | 2015 |
Deletion of the Proposed Iron Chaperones IscA/SufA Results in Accumulation of a Red Intermediate Cysteine Desulfurase IscS in Escherichia coli.
Topics: Alanine; Carbon-Sulfur Lyases; Carrier Proteins; Cysteine; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Iron; Iron-Sulfur Proteins; Molecular Chaperones; Mutagenesis, Site-Directed; Oxidation-Reduction; Pyridoxal Phosphate; Recombinant Proteins; Sulfides | 2015 |
Misfolding caused by the pathogenic mutation G47R on the minor allele of alanine:glyoxylate aminotransferase and chaperoning activity of pyridoxine.
Topics: Alanine; Alleles; Animals; Apoenzymes; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Enzyme Assays; Gene Expression; Glyoxylates; Holoenzymes; Humans; Kinetics; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Folding; Pyridoxal Phosphate; Pyridoxine; Recombinant Proteins; Solubility; Transaminases | 2015 |
Caenorhabditis elegans AGXT-1 is a mitochondrial and temperature-adapted ortholog of peroxisomal human AGT1: New insights into between-species divergence in glyoxylate metabolism.
Topics: Adaptation, Biological; Alanine; Amino Acid Sequence; Animals; Biological Evolution; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cloning, Molecular; Dimerization; Energy Metabolism; Enzyme Stability; Escherichia coli; Gene Expression; Glyoxylates; Humans; Mitochondria; Mutation; Peroxisomes; Protein Structure, Secondary; Pyridoxal Phosphate; Recombinant Proteins; Sequence Alignment; Species Specificity; Structural Homology, Protein; Temperature; Transaminases | 2016 |
Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding.
Topics: Alanine; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Levilactobacillus brevis; Molecular Docking Simulation; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Substrate Specificity; Tyrosine Decarboxylase | 2016 |
Crystal Structure of Bacillus subtilis Cysteine Desulfurase SufS and Its Dynamic Interaction with Frataxin and Scaffold Protein SufU.
Topics: Alanine; Bacillus subtilis; Bacterial Proteins; Carbon-Sulfur Lyases; Catalytic Domain; Crystallography, X-Ray; Cysteine; Deuterium Exchange Measurement; Frataxin; Iron-Binding Proteins; Iron-Sulfur Proteins; Models, Molecular; Multigene Family; Protein Binding; Protein Conformation; Protein Multimerization; Pyridoxal Phosphate; Sulfides | 2016 |
Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis.
Topics: Alanine; Catalysis; Catalytic Domain; Humans; Lysine; Models, Molecular; Molecular Structure; Protons; Pyridoxal Phosphate; Schiff Bases; Transaminases; X-Rays | 2017 |
Elucidation of the d-lysine biosynthetic pathway in the hyperthermophile Thermotoga maritima.
Topics: Alanine; Amino Acid Isomerases; Amino Acid Sequence; Cell Wall; Cloning, Molecular; Coenzymes; Enzyme Assays; Escherichia coli; Gene Expression; Gene Expression Regulation, Bacterial; Genetic Vectors; Kinetics; Lysine; Metabolic Networks and Pathways; Ornithine; Peptidoglycan; Protein Multimerization; Pyridoxal Phosphate; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Stereoisomerism; Substrate Specificity; Thermotoga maritima | 2019 |
Melanopsin for precise optogenetic activation of astrocyte-neuron networks.
Topics: 2-Amino-5-phosphonovalerate; Adenosine A2 Receptor Antagonists; Alanine; Animals; Astrocytes; Azo Compounds; Channelrhodopsins; Chelating Agents; Egtazic Acid; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Hippocampus; Inositol 1,4,5-Trisphosphate Receptors; Light; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Net; Neurons; Optogenetics; Pyridoxal Phosphate; Pyrimidines; Rod Opsins; Synaptic Potentials; Triazoles; Xanthenes | 2019 |
Structural and Kinetic Insight into the Biosynthesis of H
Topics: Alanine; Bacterial Proteins; Cystathionine beta-Synthase; Cysteine; Cysteine Synthase; Fusobacterium nucleatum; Humans; Hydro-Lyases; Hydrogen Sulfide; Kinetics; Multienzyme Complexes; Protein Conformation; Pyridoxal Phosphate; Structure-Activity Relationship; Sulfides; Yeasts | 2019 |
Structural characterization of a 2-aminoethylphosphonate:pyruvate aminotransferase from Pseudomonas aeruginosa PAO1.
Topics: Acetaldehyde; Alanine; Amino Acid Sequence; Aminoethylphosphonic Acid; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Models, Molecular; Protein Conformation; Protein Multimerization; Pseudomonas aeruginosa; Pyridoxal Phosphate; Pyruvic Acid; Recombinant Proteins; Sequence Homology, Amino Acid; Transaminases | 2021 |
Imaging active site chemistry and protonation states: NMR crystallography of the tryptophan synthase α-aminoacrylate intermediate.
Topics: Alanine; Catalysis; Catalytic Domain; Crystallography, X-Ray; Indoles; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Nuclear Magnetic Resonance, Biomolecular; Pyridoxal Phosphate; Tryptophan Synthase | 2022 |
BioWF: A Naturally-Fused, Di-Domain Biocatalyst from Biotin Biosynthesis Displays an Unexpectedly Broad Substrate Scope.
Topics: Acyl Coenzyme A; Alanine; Bacterial Proteins; Biotin; Coenzyme A Ligases; Escherichia coli; Fatty Acids; Pyridoxal Phosphate; Substrate Specificity | 2022 |
A DFT study of the active role of the phosphate group of an internal aldimine in a transamination reaction.
Topics: Alanine; Amination; Lysine; Phosphates; Protons; Pyridoxal Phosphate | 2022 |
Biochemical characterization of the first step in sulfonolipid biosynthesis in Alistipes finegoldii.
Topics: Acyl Carrier Protein; Alanine; Bacteroidetes; Cysteic Acid; Lipids; Pyridoxal Phosphate | 2022 |
Mechanistic aspects of the transamination reactions catalyzed by D-amino acid transaminase from Haliscomenobacter hydrossis.
Topics: Alanine; Amino Acids; Catalysis; Glutamic Acid; Ketoglutaric Acids; Leucine; Phenylalanine; Phosphates; Pyridoxal Phosphate; Transaminases | 2023 |