alanine and pyrazines

alanine has been researched along with pyrazines in 86 studies

Research

Studies (86)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (3.49)	18.2507
2000's	9 (10.47)	29.6817
2010's	3 (3.49)	24.3611
2020's	71 (82.56)	2.80

Authors

Authors	Studies
Agius, L; Alberti, KG; Catalano, C; Fulcher, GR; Walker, M	1
Bolli, GB; Brunetti, P; Ciofetta, M; Di Vincenzo, A; Epifano, L; Fanelli, C; Lepore, M; Modarelli, F; Pampanelli, S	1
Alberti, KG; Farrer, M; Fulcher, GR; Johnson, AS; Walker, M	1
Kamiya, K; Kodama, I; Mitcheson, JS; Sanguinetti, MC; Yasui, K	1
Efskind, J; Hoven, GB; Rømming, C; Undheim, K	1
Breslin, MJ; Duggan, ME; Fernandez-Metzler, C; Halczenko, W; Hunt, CA; Hutchinson, JH; Leu, CT; Merkle, KM; Naylor-Olsen, AM; Prueksaritanont, T; Rodan, SB; Stump, G; Wallace, A	1
Basiuk, VA	1
Ackermans, MT; canh Hung, N; Endert, E; Kager, PA; Sauerwein, HP; van Thien, H; Weverling, GJ	1
Hirschmann, R; Mowery, BP; Neelamkavil, S; Smith, AB; Thornton, ER	1
Kashman, Y; Lang, S; Pappo, D; Vartanian, M	1
Arison, B; Birzin, E; Chen, KH; Cheng, FC; Feng, JJ; Hirschmann, R; Lin, A; Neelamkavil, S; Smith, AB; Taylor, L; Thornton, ER	1
Weber, AL	1
Jochmans, D; Neyts, J	1
Check Hayden, E	1
De Clercq, E	1
Li, J; Qi, C; Shen, L; Wang, Y; Zhang, Q	1
Dong, L; Gao, J; Hu, S	1
Duan, Y; Zhou, C; Zhu, HL	1
Chan, MCW; Chen, D; Cheung, PP; Choy, KT; Chu, DKW; Huang, X; Hui, KPY; Kaewpreedee, P; Peiris, M; Sia, SF; Wong, AY; Yen, HL	1
Cutrell, JB; Jodlowski, TZ; Monogue, ML; Sanders, JM	1
Şimşek Yavuz, S; Ünal, S	1
Costanzo, M; De Giglio, MAR; Roviello, GN	1
Hsueh, PR; Jean, SS; Lee, PI	1
Ge, J; Li, H; Liu, Z	1
Alkindi, N; Mazer-Amirshahi, M; Mehta, N; Pourmand, A	1
Ahsan, W; Alhazmi, HA; Bratty, MA; Javed, S; Najmi, A	1
Delang, L; Neyts, J	1
Baggett, MV; Rhee, EP; Shepard, JO; Sise, ME; Stevens, JS	1
Campos, L; Gouveia, CC	1
Chen, D; Dong, L; Pan, X; Peng, C; Yang, L	1
Li, C; Ren, L; Wang, L	1
Martinez, MA	1
Chen, CZ; Gorshkov, K; Lo, DC; Xu, M; Zheng, W; Zhu, W	1
Li, Z; Liu, Y; Wang, D	1
Ajaz, SJ; Banday, AH; Shameem, SA	1
Bellutti-Enders, F; Hartmann, K; Jamiolkowski, D; Leuppi-Taegtmeyer, A; Manjaly Thomas, ZR; Scherer Hofmeier, K; Steveling-Klein, E	1
Carvalho Junior, RN; J C Neto, AM; Martins, AY; Reis, AF; S Costa, JF; Silva Arouche, TD	1
Al-Yamani, MJ; Asdaq, SMB; Jomah, S	1
Ijaz, M; Khan, M; Kharaba, ZJ; Murtaza, G; Shamim, S	1
Barfuss, P; Demirbag, S; Khan, KS; Le, TK; Ng, WL; Paris, C; Robson, F; Rocchi, P	1
Emanuela, C; Francesco, L; Giorgia, G; Pasquale, N; Roberto, P; Sara, D	1
Guan, W; Lan, W; Ou, J; Wu, J; Wu, X; Yan, Y; Zhang, J; Zhang, Q; Zhao, S	1
Fätkenheuer, G; Malin, JJ; Rybniker, J; Simonis, A; Theobald, SJ	1
Lai, WF; Sreekanth Reddy, O	1
Ban, K; Choi, SW; Go, YY; Jung, E; Kim, SJ; Lee, J; Lee, JH; Moon, SH; Park, HJ; Park, SJ; Park, SM; Park, YG; Shin, JS	1
Dimopoulos, MA; Fotiou, D; Gavriatopoulou, M; Kastritis, E; Korompoki, E; Migkou, M; Ntanasis-Stathopoulos, I; Psaltopoulou, T; Terpos, E; Tzanninis, IG	1
Vaidyanathan, G	1
Amel Jamehdar, S; Milani, N; Movaqar, A; Soleimanpour, S; Yaghoubi, A	1
Mishra, SK; Tripathi, T	1
Ambrosino, I; Barbagelata, E; Ciarambino, T; Corbi, G; Moretti, AM; Politi, C	1
Govil, A; Luckett, K; Miller-Handley, H	1
Durvasula, R; Durvasula, SR; Kunamneni, A; Maciorowski, D; Ogaugwu, C	1
Kumar, D; Trivedi, N; Verma, A	1
da Silva, S; Martinková, I; Petroušová, L; Rožnovský, L	1
Wen, S; Xu, X; Yadav, AK; Yu, L	1
Dehghan, H; Fazlzadeh, A; Haddad, F; Kheirabadi, D; Mousavi-Roknabadi, RS; Rezaeisadrabadi, M	1
Saladini, F; Vicenti, I; Zazzi, M	1
Abou-Sleymane, G; Al Faraj, A; Badro, DA; Daou, F; Khanafer, N; Tobaiqy, M	1
Brügel, M; Habler, K; Liebchen, U; Paal, M; Scharf, C; Schönermarck, U; Teupser, D; Vogeser, M	1
Danduga, RCSR; James, RA; Kandaswamy, DK; Raj, CTD; Rajasabapathy, R	1
Amato, L; Cruciani, F; Davoli, M; De Crescenzo, F; Mitrova, Z; Saulle, R; Vecchi, S	1
Alotaibi, NH; Bokharee, N; Khan, YH; Khokhar, A; Mallhi, TH; Rasheed, M	1
Celik, I; Duzgun, Z; Erol, M	1
Fujii, H; Goda, S; Hiraoka, N; Matsumoto, Y; Matsuyama, A; Omura, A; Ono, S; Shiotsu, S; Suga, Y; Sugitani, M; Takumi, C; Tanaka, S; Tsuji, T; Yuba, T	1
Kami, M; Murayama, A; Ozaki, A; Tanimoto, T; Ueda, M	1
Aliota, MT; Bonnac, LF; Geraghty, RJ	1
Bayrakci, B; Cengiz, AB; Gülhan, B; Gürlevik, SL; Kesici, S; Kurt Sukur, ED; Oygar, PD; Ozen, S; Ozsurekci, Y; Topaloglu, R	1
Chandra, PP; Jain, S; Potschka, H; Tripathi, M; Vohora, D	1
Chao, CM; Hsueh, PR; Lai, CC	1
Kundu, S; Sarkar, D	1
Bhatti, K; Chidurala, RM; Das, R; Mehta, DK; Rana, M; Saini, M	1
Khaheshi, I; Shahrbaf, MA; Tabary, M	1
Berk, H; Demir Önder, K; Öztoprak, N; Seremet Keskin, A; Seyman, D	1
Alver, Ö; Ouma, CNM; Parlak, C; Ramasami, P; Rhyman, L	1
Assis, LC; da Cunha, EFF; de Almeida La Porta, F; de Castro Ramalho, T; de Castro, AA; de Jesus, JPA; Kuca, K; Nepovimova, E	1
Al-Ardhi, FM; Al-Tannak, NF; Alhunayan, A; Novotny, L	1
Abolnezhadian, F; Alavi, SM; Ghafourian, M; Khodadadi, A; Mahmoudian-Sani, MR; Nashibi, R; Sharhani, A; Shohan, M	1
Baig, MS; Li, P; Li, Y; Ma, Z; Pan, Q; Rajpoot, S; Saqib, U; Wang, Y; Yu, P	1
Abdel-Daim, MM; Behl, T; Bungau, SG; Endres, L; Nechifor, AC; Negru, PA; Pasca, B; Radu, AF; Stoicescu, M; Tit, DM; Vesa, CM	1
Chaturvedi, N; Chauhan, P; Karthic, A; Kesarwani, V; Kushwaha, SK; Singh, RK; Yadav, BS; Yadav, PK	1
Fischer, M; Luck, M; Müller, P; Scheidt, HA	1
Belal, F; El-Awady, M; Elmansi, H; Shabana, RA	1
Abdelazim, AH; Hasan, MA; Osman, AO; Ramzy, S	1
Tsuji, M	1
Cui, H; Hayat, K; Ho, CT; Xia, X; Zhang, X; Zhou, T	1
Cui, H; Hayat, K; Ho, CT; Xia, X; Zhai, Y; Zhang, F; Zhang, X; Zhou, T	1

Reviews

45 review(s) available for alanine and pyrazines

Article	Year
The path towards effective antivirals against rabies. Vaccine, 2019, 08-02, Volume: 37, Issue:33 Topics: Adenine; Adenosine; Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Drug Repositioning; Humans; Post-Exposure Prophylaxis; Pyrazines; Pyrrolidines; Rabies; Rabies virus	2019
New Nucleoside Analogues for the Treatment of Hemorrhagic Fever Virus Infections. Chemistry, an Asian journal, 2019, Nov-18, Volume: 14, Issue:22 Topics: Adenine; Adenosine; Alanine; Amides; Antiviral Agents; Base Pairing; Ebolavirus; Guanine; Hemorrhagic Fevers, Viral; Humans; Nucleotides; Phosphoric Acids; Pyrazines; Triazines	2019
Clinical trial analysis of 2019-nCoV therapy registered in China. Journal of medical virology, 2020, Volume: 92, Issue:6 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Betacoronavirus; China; Chloroquine; Clinical Trials as Topic; Coronavirus Infections; COVID-19; Disease Management; Disease Outbreaks; Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional; Pandemics; Pneumonia, Viral; Practice Guidelines as Topic; Pyrazines; SARS-CoV-2	2020
Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19): A Review. JAMA, 2020, May-12, Volume: 323, Issue:18 Topics: Adenosine Monophosphate; Adrenal Cortex Hormones; Alanine; Amides; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antiviral Agents; Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Immunoglobulins; Immunologic Factors; Indoles; Lopinavir; Oseltamivir; Pandemics; Pneumonia, Viral; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2; Withholding Treatment	2020
Antiviral treatment of COVID-19 Turkish journal of medical sciences, 2020, 04-21, Volume: 50, Issue:SI-1 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Combinations; Humans; Hydroxychloroquine; Ivermectin; Lopinavir; Nitro Compounds; Pandemics; Pneumonia, Viral; Pyrazines; Ritonavir; SARS-CoV-2; Thiazoles	2020
Treatment options for COVID-19: The reality and challenges. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2020, Volume: 53, Issue:3 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Azithromycin; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Serotherapy; Drug Combinations; Humans; Hydroxychloroquine; Immunization, Passive; Lopinavir; Pandemics; Pneumonia, Viral; Pyrazines; Ritonavir; RNA-Dependent RNA Polymerase; SARS-CoV-2; Teicoplanin	2020
Scientific research progress of COVID-19/SARS-CoV-2 in the first five months. Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:12 Topics: Adenosine Monophosphate; Alanine; Amides; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Antiviral Agents; Betacoronavirus; Clinical Laboratory Techniques; Coronavirus Infections; COVID-19; COVID-19 Serotherapy; COVID-19 Testing; COVID-19 Vaccines; Disease Progression; Gene Expression Regulation; Host-Pathogen Interactions; Humans; Immunization, Passive; Pandemics; Peptidyl-Dipeptidase A; Pneumonia, Viral; Pyrazines; SARS-CoV-2; Severity of Illness Index; Spike Glycoprotein, Coronavirus; Viral Vaccines	2020
Pharmacotherapy in COVID-19; A narrative review for emergency providers. The American journal of emergency medicine, 2020, Volume: 38, Issue:7 Topics: Adenosine Monophosphate; Adrenal Cortex Hormones; Alanine; Amides; Angiotensin-Converting Enzyme Inhibitors; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Drug Therapy, Combination; Emergency Service, Hospital; Humans; Hydroxychloroquine; Interleukin-6; Pandemics; Pneumonia, Viral; Pyrazines; Randomized Controlled Trials as Topic; SARS-CoV-2	2020
Treatment of SARS-CoV-2: How far have we reached? Drug discoveries & therapeutics, 2020, May-06, Volume: 14, Issue:2 Topics: Adenosine Monophosphate; Alanine; Amides; Antibodies, Monoclonal, Humanized; Antiviral Agents; Betacoronavirus; Chloroquine; Clinical Trials as Topic; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; Darunavir; Drug Combinations; Humans; Hydroxychloroquine; Immunization, Passive; Indoles; Interferon-alpha; Interferon-beta; Lopinavir; Pandemics; Pneumonia, Viral; Pyrazines; Ritonavir; SARS-CoV-2	2020
Medical treatment options for COVID-19. European heart journal. Acute cardiovascular care, 2020, Volume: 9, Issue:3 Topics: Adenosine Monophosphate; Administration, Intravenous; Alanine; Amides; Antibodies, Monoclonal, Humanized; Antiviral Agents; Betacoronavirus; Chloroquine; Clinical Trials as Topic; Coronavirus Infections; COVID-19; Cytochrome P-450 CYP3A Inhibitors; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunologic Factors; Lopinavir; Pandemics; Pneumonia, Viral; Pyrazines; Recombinant Proteins; RNA, Viral; SARS-CoV-2	2020
Coronavirus Disease 2019: Clinical Review. Acta medica portuguesa, 2020, Jul-01, Volume: 33, Issue:7-8 Topics: Adenosine Monophosphate; Alanine; Amides; Animals; Antiviral Agents; Azithromycin; Betacoronavirus; Blood Coagulation Disorders; China; Chiroptera; Chloroquine; Coronavirus Infections; COVID-19; Glucocorticoids; Humans; Hydroxychloroquine; Infectious Disease Incubation Period; Lopinavir; Lung; Pandemics; Pneumonia, Viral; Prognosis; Pyrazines; Radiography, Thoracic; Reverse Transcriptase Polymerase Chain Reaction; SARS-CoV-2; Symptom Assessment	2020
Potential drugs for the treatment of the novel coronavirus pneumonia (COVID-19) in China. Virus research, 2020, Volume: 286 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Betacoronavirus; China; Chloroquine; Coronavirus Infections; COVID-19; Drug Combinations; Drugs, Chinese Herbal; Humans; Indoles; Interferons; Lopinavir; Lung; Pandemics; Pneumonia, Viral; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2; Survival Analysis	2020
Antiviral mechanisms of candidate chemical medicines and traditional Chinese medicines for SARS-CoV-2 infection. Virus research, 2020, Volume: 286 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Betacoronavirus; China; Coronavirus Infections; COVID-19; Drug Combinations; Drugs, Chinese Herbal; Humans; Hydroxychloroquine; Indoles; Interferons; Lopinavir; Pandemics; Pneumonia, Viral; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2; Survival Analysis; Teicoplanin	2020
Clinical Trials of Repurposed Antivirals for SARS-CoV-2. Antimicrobial agents and chemotherapy, 2020, 08-20, Volume: 64, Issue:9 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Drug Administration Schedule; Drug Combinations; Drug Repositioning; Humans; Hydroxychloroquine; Interferons; Lopinavir; Pandemics; Pneumonia, Viral; Pyrazines; Randomized Controlled Trials as Topic; Ribavirin; Ritonavir; SARS-CoV-2; Survival Analysis; Treatment Outcome	2020
RNA-Dependent RNA Polymerase as a Target for COVID-19 Drug Discovery. SLAS discovery : advancing life sciences R & D, 2020, Volume: 25, Issue:10 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; COVID-19 Drug Treatment; Drug Discovery; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Middle East Respiratory Syndrome Coronavirus; Pyrazines; RNA-Dependent RNA Polymerase; SARS-CoV-2; Viral Proteins; Virus Replication	2020
An overview of the safety, clinical application and antiviral research of the COVID-19 therapeutics. Journal of infection and public health, 2020, Volume: 13, Issue:10 Topics: Adenosine Monophosphate; Alanine; Amides; Angiotensin-Converting Enzyme Inhibitors; Antimalarials; Antiviral Agents; Betacoronavirus; Biomedical Research; Coronavirus Infections; COVID-19; COVID-19 Serotherapy; Drug Combinations; Drug Development; Drugs, Chinese Herbal; Humans; Hydroxychloroquine; Immunization, Passive; Indoles; Interferons; Lopinavir; Pandemics; Pneumonia, Viral; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2	2020
Emerging treatments in COVID-19: Adverse drug reactions including drug hypersensitivities. The Journal of allergy and clinical immunology, 2020, Volume: 146, Issue:4 Topics: Adenosine Monophosphate; Adrenal Cortex Hormones; Alanine; Amides; Antibodies, Monoclonal, Humanized; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Cytokine Release Syndrome; Drug Hypersensitivity; Humans; Immunity, Innate; Immunologic Factors; Indoles; Infliximab; Interleukin 1 Receptor Antagonist Protein; Nitriles; Pandemics; Pneumonia, Viral; Pyrazines; Pyrazoles; Pyrimidines; SARS-CoV-2; Severity of Illness Index	2020
Clinical efficacy of antivirals against novel coronavirus (COVID-19): A review. Journal of infection and public health, 2020, Volume: 13, Issue:9 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Drug Combinations; Humans; Indoles; Lopinavir; Pandemics; Pneumonia, Viral; Pyrazines; Ritonavir; SARS-CoV-2	2020
Potential strategies for combating COVID-19. Archives of virology, 2020, Volume: 165, Issue:11 Topics: Adenosine Monophosphate; Adrenal Cortex Hormones; Alanine; Amides; Antibodies, Monoclonal, Humanized; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Serotherapy; COVID-19 Vaccines; Cytokine Release Syndrome; Drug Combinations; Humans; Hydroxychloroquine; Immunization, Passive; Immunologic Factors; Indoles; Interleukin 1 Receptor Antagonist Protein; Lopinavir; Pandemics; Pneumonia, Viral; Pyrazines; Ritonavir; SARS-CoV-2; Severity of Illness Index; Viral Vaccines	2020
Coronavirus RNA Proofreading: Molecular Basis and Therapeutic Targeting. Molecular cell, 2020, 09-03, Volume: 79, Issue:5 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Cytidine; Genome, Viral; Humans; Hydroxylamines; Molecular Targeted Therapy; Mutation; Pandemics; Pneumonia, Viral; Pyrazines; Ribonucleosides; RNA, Viral; SARS-CoV-2; Severity of Illness Index; Transcription, Genetic; Viral Nonstructural Proteins; Virus Replication	2020
Current treatment of COVID-19 in renal patients: hope or hype? Internal and emergency medicine, 2020, Volume: 15, Issue:8 Topics: Adenosine Monophosphate; Adrenal Cortex Hormones; Alanine; Amides; Antibodies, Monoclonal; Cobicistat; Coronavirus Infections; COVID-19; Darunavir; Drug Combinations; Humans; Kidney; Lopinavir; Pandemics; Pneumonia, Viral; Pyrazines; Renal Insufficiency, Chronic; Renal Replacement Therapy; Ritonavir	2020
COVID-19: Antiviral Agents, Antibody Development and Traditional Chinese Medicine. Virologica Sinica, 2020, Volume: 35, Issue:6 Topics: Adenosine Monophosphate; Alanine; Amides; Animals; Antibodies, Viral; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; Drug Repositioning; Humans; Immunization, Passive; Medicine, Chinese Traditional; Pandemics; Pyrazines; SARS-CoV-2; World Health Organization	2020
A comparative analysis of remdesivir and other repurposed antivirals against SARS-CoV-2. EMBO molecular medicine, 2021, 01-11, Volume: 13, Issue:1 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Benzamidines; COVID-19 Drug Treatment; Drug Repositioning; Esters; Guanidines; Guanine; Humans; Indoles; Lopinavir; Protease Inhibitors; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2; Virus Internalization; Virus Replication	2021
Tackling COVID-19 Using Remdesivir and Favipiravir as Therapeutic Options. Chembiochem : a European journal of chemical biology, 2021, 03-16, Volume: 22, Issue:6 Topics: Adenosine Monophosphate; Alanine; Amides; Animals; Antiviral Agents; COVID-19 Drug Treatment; Humans; Pyrazines; SARS-CoV-2	2021
Emerging treatment strategies for COVID-19 infection. Clinical and experimental medicine, 2021, Volume: 21, Issue:2 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Chloroquine; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; COVID-19 Vaccines; Humans; Hydroxychloroquine; Immunization, Passive; Palliative Care; Pyrazines; SARS-CoV-2; Treatment Outcome	2021
An effective drug against COVID-19: reality or dream? Expert review of respiratory medicine, 2021, Volume: 15, Issue:4 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; COVID-19 Drug Treatment; Drug Development; Humans; Pandemics; Pyrazines	2021
One year update on the COVID-19 pandemic: Where are we now? Acta tropica, 2021, Volume: 214 Topics: Adenosine Monophosphate; Alanine; Amides; Animals; Antiviral Agents; Chloroquine; Clinical Trials as Topic; Coronavirus; Coronavirus Infections; COVID-19; COVID-19 Vaccines; Drug Combinations; Drug Repositioning; Glucocorticoids; Humans; Hydroxychloroquine; Indoles; Ivermectin; Lopinavir; Mutation; Pandemics; Phytotherapy; Plant Extracts; Pyrazines; Ritonavir; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Tinospora; Viral Zoonoses	2021
Treatment Options for Coronavirus Disease 2019 in Patients With Reduced or Absent Kidney Function. Advances in chronic kidney disease, 2020, Volume: 27, Issue:5 Topics: Adenosine Monophosphate; Alanine; Amides; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Antiviral Agents; Chloroquine; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; COVID-19 Vaccines; Creatinine; Cytidine; Dexamethasone; Drug Combinations; Drug Interactions; Humans; Hydroxychloroquine; Hydroxylamines; Immunization, Passive; Interferons; Janus Kinase Inhibitors; Lopinavir; Pyrazines; Renal Elimination; Renal Insufficiency, Chronic; Renal Replacement Therapy; Ribavirin; Ritonavir; SARS-CoV-2	2020
Therapeutic and Vaccine Options for COVID-19: Status after Six Months of the Disease Outbreak. SLAS discovery : advancing life sciences R & D, 2021, Volume: 26, Issue:3 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; COVID-19 Vaccines; Dexamethasone; Humans; Immunization, Passive; Pyrazines; SARS-CoV-2; Viral Proteins	2021
Possible treatment and strategies for COVID-19: review and assessment. European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:23 Topics: Adenosine Monophosphate; Alanine; Amides; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Antibodies, Neutralizing; Antiparasitic Agents; Antiviral Agents; Cannabinoids; Chloroquine; Complement Inactivating Agents; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; COVID-19 Vaccines; Dexamethasone; Drug Combinations; Enzyme Inhibitors; Humans; Hydroxychloroquine; Immunization, Passive; Indoles; Interferons; Ivermectin; Lopinavir; Nitro Compounds; Pyrazines; Ritonavir; SARS-CoV-2; Teicoplanin; Tetracyclines; Thiazoles	2020
Antiviral treatment in COVID-19: which is the most promising?-a narrative review. Annals of palliative medicine, 2021, Volume: 10, Issue:1 Topics: Adenosine Monophosphate; Alanine; Amides; Antibodies, Monoclonal, Humanized; Antiviral Agents; Azetidines; Chloroquine; COVID-19; COVID-19 Serotherapy; Drug Combinations; Humans; Hydroxychloroquine; Immunization, Passive; Indoles; Interferons; Ivermectin; Lopinavir; Nitro Compounds; Oseltamivir; Purines; Pyrazines; Pyrazoles; Ribavirin; Ritonavir; Sulfonamides; Thiazoles	2021
A complementary critical appraisal on systematic reviews regarding the most efficient therapeutic strategies for the current COVID-19 (SARS-CoV-2) pandemic. Journal of medical virology, 2021, Volume: 93, Issue:5 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Chloroquine; COVID-19; COVID-19 Drug Treatment; Cytokine Release Syndrome; Databases, Factual; Humans; Hydroxychloroquine; Immunoglobulins; Lopinavir; Pandemics; Pyrazines; Respiration, Artificial; Ritonavir; SARS-CoV-2	2021
SARS-CoV-2 RNA-dependent RNA polymerase as a therapeutic target for COVID-19. Expert opinion on therapeutic patents, 2021, Volume: 31, Issue:4 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; COVID-19 Drug Treatment; Cytidine; Drug Development; Drug Repositioning; Humans; Hydroxylamines; Pyrazines; RNA-Dependent RNA Polymerase; SARS-CoV-2	2021
The History, Efficacy, and Safety of Potential Therapeutics: A Narrative Overview of the Complex Life of COVID-19. International journal of environmental research and public health, 2021, 01-22, Volume: 18, Issue:3 Topics: Adenosine Monophosphate; Alanine; Amides; Antibodies, Monoclonal, Humanized; Antiviral Agents; COVID-19; COVID-19 Serotherapy; Humans; Hydroxychloroquine; Immunization, Passive; Pandemics; Pyrazines	2021
COVID-19: molecular pathophysiology, genetic evolution and prospective therapeutics-a review. Archives of microbiology, 2021, Volume: 203, Issue:5 Topics: Adenosine Monophosphate; Alanine; Amides; Animals; Antiviral Agents; Chloroquine; COVID-19; COVID-19 Serotherapy; Dexamethasone; Drug Repositioning; Evolution, Molecular; Humans; Hydroxychloroquine; Immunization, Passive; Lopinavir; Pandemics; Phylogeny; Prospective Studies; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2	2021
[The praise of uncertainty: a systematic living review to evaluate the efficacy and safety of drug treatments for patients with covid-19.] Recenti progressi in medicina, 2021, Volume: 112, Issue:3 Topics: Adenosine Monophosphate; Adrenal Cortex Hormones; Alanine; Amides; Antibodies, Monoclonal, Humanized; Antiviral Agents; Combined Modality Therapy; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; Drug Combinations; Drug Repositioning; Humans; Hydroxychloroquine; Immunization, Passive; Immunoglobulins, Intravenous; Lopinavir; Mesenchymal Stem Cell Transplantation; Pandemics; Pyrazines; Randomized Controlled Trials as Topic; Ritonavir; SARS-CoV-2; Treatment Outcome; Uncertainty	2021
Pharmacological interventions for COVID-19: a systematic review of observational studies and clinical trials. Expert review of anti-infective therapy, 2021, Volume: 19, Issue:10 Topics: Adenosine Monophosphate; Alanine; Amides; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Antimalarials; Antiviral Agents; Chloroquine; Clinical Trials as Topic; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; Humans; Hydroxychloroquine; Immunization, Passive; Indoles; Intensive Care Units; Length of Stay; Lopinavir; Methylprednisolone; Observational Studies as Topic; Patient Admission; Pyrazines; Ritonavir; SARS-CoV-2; Survival Rate	2021
Broad-Spectrum Antiviral Strategies and Nucleoside Analogues. Viruses, 2021, 04-13, Volume: 13, Issue:4 Topics: Adenosine Monophosphate; Alanine; Amides; Animals; Antiviral Agents; COVID-19 Drug Treatment; Hemorrhagic Fever, Ebola; Humans; Middle East Respiratory Syndrome Coronavirus; Mutagenesis; Nucleosides; Pyrazines; Ribavirin; SARS-CoV-2; Virus Replication; Zika Virus; Zika Virus Infection	2021
Management of COVID-19 in patients with seizures: Mechanisms of action of potential COVID-19 drug treatments and consideration for potential drug-drug interactions with anti-seizure medications. Epilepsy research, 2021, Volume: 174 Topics: Adenosine Monophosphate; Alanine; Amides; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Anticonvulsants; Antiviral Agents; Chloroquine; COVID-19; COVID-19 Drug Treatment; Cytochrome P-450 CYP3A Inducers; Dexamethasone; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Epilepsy; Glucocorticoids; Humans; Hydroxychloroquine; Interleukin 1 Receptor Antagonist Protein; Ivermectin; Lopinavir; Pyrazines; Ritonavir; SARS-CoV-2	2021
Clinical efficacy of antiviral agents against coronavirus disease 2019: A systematic review of randomized controlled trials. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2021, Volume: 54, Issue:5 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Carbamates; Cobicistat; COVID-19 Drug Treatment; Darunavir; Dibenzothiepins; Drug Combinations; Drug Therapy, Combination; Humans; Imidazoles; Indoles; Iran; Lopinavir; Morpholines; Pyrazines; Pyridones; Pyrrolidines; Randomized Controlled Trials as Topic; Ritonavir; SARS-CoV-2; Sofosbuvir; Treatment Outcome; Triazines; Valine	2021
Synthetic Attempts Towards Eminent Anti-viral Candidates of SARS-CoV. Mini reviews in medicinal chemistry, 2022, Volume: 22, Issue:2 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Humans; Lopinavir; Pyrazines; SARS-CoV-2	2022
Clinical Efficacy of Remdesivir and Favipiravir in the Treatment of COVID-19 Patients: Scenario so far. Current drug research reviews, 2022, Volume: 14, Issue:1 Topics: Adenosine Monophosphate; Alanine; Amides; COVID-19 Drug Treatment; Humans; Pyrazines; SARS-CoV-2; Treatment Outcome	2022
Comparison of remdesivir and favipiravir - the anti-Covid-19 agents mimicking purine RNA constituents. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2022, Volume: 166, Issue:1 Topics: Adenosine Monophosphate; Alanine; Amides; COVID-19 Drug Treatment; Humans; Pyrazines; RNA, Viral; SARS-CoV-2	2022
Therapeutic dilemmas in addressing SARS-CoV-2 infection: Favipiravir versus Remdesivir. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 147 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; COVID-19 Drug Treatment; Humans; Pyrazines; SARS-CoV-2	2022
Computational Analysis Reveals Monomethylated Triazolopyrimidine as a Novel Inhibitor of SARS-CoV-2 RNA-Dependent RNA Polymerase (RdRp). Molecules (Basel, Switzerland), 2022, Jan-26, Volume: 27, Issue:3 Topics: Adenosine Monophosphate; Alanine; Amides; Catalytic Domain; Computational Biology; Coronavirus RNA-Dependent RNA Polymerase; COVID-19; COVID-19 Drug Treatment; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Pyrazines; Pyrimidines; RNA-Dependent RNA Polymerase; RNA, Viral; SARS-CoV-2; Triazoles; Virus Replication	2022

Trials

5 trial(s) available for alanine and pyrazines

Article	Year
Metabolic effects of suppression of nonesterified fatty acid levels with acipimox in obese NIDDM subjects. Diabetes, 1992, Volume: 41, Issue:11 Topics: 3-Hydroxybutyric Acid; Alanine; Blood Glucose; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Glycerol; Humans; Hydroxybutyrates; Hypolipidemic Agents; Insulin; Lactates; Male; Middle Aged; Obesity; Pyrazines; Pyruvates; Triglycerides	1992
Acipimox increases glucose disposal in normal man independent of changes in plasma nonesterified fatty acid concentration and whole-body lipid oxidation rate. Metabolism: clinical and experimental, 1993, Volume: 42, Issue:3 Topics: Adult; Alanine; C-Peptide; Diabetes Mellitus, Type 2; Double-Blind Method; Fatty Acids, Nonesterified; Glucagon; Glucose; Glycerol; Growth Hormone; Humans; Hydroxybutyrates; Hypolipidemic Agents; Insulin; Lactates; Lipid Metabolism; Male; Oxidation-Reduction; Pyrazines; Pyruvates; Radioimmunoassay; Time Factors	1993
FFAs are not involved in regulation of gluconeogenesis and glycogenolysis in adults with uncomplicated P. falciparum malaria. American journal of physiology. Endocrinology and metabolism, 2004, Volume: 287, Issue:4 Topics: Adult; Alanine; Fatty Acids, Nonesterified; Female; Gluconeogenesis; Glucose; Glycogen; Humans; Hypolipidemic Agents; Insulin; Interleukin-10; Lactic Acid; Malaria, Falciparum; Male; Pyrazines; Tumor Necrosis Factor-alpha	2004
Favipiravir use in children with COVID-19 and acute kidney injury: is it safe? Pediatric nephrology (Berlin, Germany), 2021, Volume: 36, Issue:11 Topics: Acute Kidney Injury; Adenosine Monophosphate; Adolescent; Alanine; Amides; Child; COVID-19; COVID-19 Drug Treatment; Creatinine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Male; Pyrazines; Renal Elimination; SARS-CoV-2; Systemic Inflammatory Response Syndrome; Treatment Outcome	2021
The therapeutic efficacy of quercetin in combination with antiviral drugs in hospitalized COVID-19 patients: A randomized controlled trial. European journal of pharmacology, 2022, Jan-05, Volume: 914 Topics: Adenosine Monophosphate; Alanine; Amides; Antioxidants; Antiviral Agents; Biomarkers; COVID-19; COVID-19 Drug Treatment; Drug Monitoring; Female; Hemoglobins; Humans; Male; Middle Aged; Outcome and Process Assessment, Health Care; Patient Discharge; Pyrazines; Quercetin; Respiratory Rate	2022

Other Studies

36 other study(ies) available for alanine and pyrazines

Article	Year
Post-hypoglycaemic hyperketonaemia does not contribute to brain metabolism during insulin-induced hypoglycaemia in humans. Diabetologia, 1993, Volume: 36, Issue:11 Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Brain; Cognition; Diabetes Mellitus, Type 1; Female; Glycerol; Homeostasis; Hormones; Humans; Hydroxybutyrates; Hypoglycemia; Hypolipidemic Agents; Insulin; Insulinoma; Ketone Bodies; Lactates; Lipolysis; Male; Pancreatic Neoplasms; Pyrazines; Reaction Time	1993
Open channel block of HERG K(+) channels by vesnarinone. Molecular pharmacology, 2001, Volume: 60, Issue:2 Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Cardiotonic Agents; Cation Transport Proteins; DNA-Binding Proteins; Electrophysiology; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; KCNQ Potassium Channels; KCNQ1 Potassium Channel; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Conformation; Pyrazines; Quinolines; Sequence Homology, Amino Acid; Time Factors; Trans-Activators; Transcriptional Regulator ERG; Xenopus laevis	2001
Ru(II)-catalyzed cascade reactions in stereocontrolled construction of rigid as-indacene-bridged bis(alpha-amino acid) derivatives. The Journal of organic chemistry, 2002, Apr-19, Volume: 67, Issue:8 Topics: Alanine; Alkylation; Amino Acids; Bridged-Ring Compounds; Catalysis; Chemistry, Organic; Crystallography, X-Ray; Cystine; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Pyrazines; Ruthenium; Stereoisomerism	2002
Non-peptide alphavbeta3 antagonists. Part 6: design and synthesis of alphavbeta3 antagonists containing a pyridone or pyrazinone central scaffold. Bioorganic & medicinal chemistry letters, 2003, May-19, Volume: 13, Issue:10 Topics: Alanine; Drug Design; Humans; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Integrin alphaVbeta3; Molecular Mimicry; Oligopeptides; Protein Binding; Pyrazines; Pyridones; Radioimmunoassay; Structure-Activity Relationship	2003
Calculated gas-phase infrared spectra of imidazo[1,2-a]pyrazinediones derived from alanine. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2003, Volume: 59, Issue:8 Topics: Alanine; Imidazoles; Models, Chemical; Molecular Conformation; Pyrazines; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared	2003
A practical synthesis of Nalpha-Fmoc-L-pyrazinylalanine via Schöllkopf's chiral auxiliary. The journal of peptide research : official journal of the American Peptide Society, 2005, Volume: 65, Issue:1 Topics: Alanine; Molecular Structure; Pyrazines; Stereoisomerism	2005
Synthesis of cyclic endiamino peptides. Journal of the American Chemical Society, 2005, Jun-01, Volume: 127, Issue:21 Topics: Alanine; Amino Acids, Diamino; Glycine; Peptides, Cyclic; Pyrazines	2005
Replacement of Phe6, Phe7, and Phe11 of D-Trp8-somatostatin-14 with L-pyrazinylalanine. Predicted and observed effects on binding affinities at hSST2 and hSST4. An unexpected effect of the chirality of Trp8 on NMR spectra in methanol. Journal of medicinal chemistry, 2005, Jun-16, Volume: 48, Issue:12 Topics: Alanine; Binding Sites; Magnetic Resonance Spectroscopy; Membrane Proteins; Methanol; Models, Molecular; Peptides, Cyclic; Phenylalanine; Pyrazines; Receptors, Somatostatin; Solvents; Somatostatin; Stereoisomerism; Structure-Activity Relationship	2005
Sugar-driven prebiotic synthesis of 3,5(6)-dimethylpyrazin-2-one: a possible nucleobase of a primitive replication process. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 2008, Volume: 38, Issue:4 Topics: Alanine; Amides; Amines; Ammonium Chloride; Base Composition; Carbohydrates; Chemistry; Evolution, Chemical; Glyceraldehyde; Hydrogen-Ion Concentration; Models, Chemical; Origin of Life; Pyrazines; Spectrophotometry, Ultraviolet; Time Factors	2008
Experimental drugs poised for use in Ebola outbreak. Nature, 2018, Volume: 557, Issue:7706 Topics: Adenosine Monophosphate; Alanine; Amides; Antibodies, Monoclonal; Congo; Disease Outbreaks; Drugs, Investigational; Ebola Vaccines; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Internationality; Pyrazines; Ribonucleotides	2018
Discovering drugs to treat coronavirus disease 2019 (COVID-19). Drug discoveries & therapeutics, 2020, Volume: 14, Issue:1 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Betacoronavirus; Chloroquine; Clinical Studies as Topic; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Discovery; Humans; Indoles; Pandemics; Pneumonia, Viral; Pyrazines; Ribonucleotides; SARS-CoV-2; Virus Replication	2020
Advance of promising targets and agents against COVID-19 in China. Drug discovery today, 2020, Volume: 25, Issue:5 Topics: Adenine; Adenosine Monophosphate; Alanine; Amides; Antimalarials; Antiviral Agents; Betacoronavirus; China; Chloroquine; Clinical Trials as Topic; Cobicistat; Coronavirus 3C Proteases; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cysteine Endopeptidases; Dibenzothiepins; Drug Combinations; Drug Discovery; Drug Therapy, Combination; Emtricitabine; Humans; Hydroxychloroquine; Indoles; Lopinavir; Medicine, Chinese Traditional; Morpholines; Oseltamivir; Oxazines; Pandemics; Pneumonia, Viral; Pyrazines; Pyridines; Pyridones; Ritonavir; RNA-Dependent RNA Polymerase; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Tenofovir; Thiepins; Triazines; Viral Nonstructural Proteins	2020
Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro. Antiviral research, 2020, Volume: 178 Topics: Adenosine Monophosphate; Alanine; Amides; Animals; Antimetabolites; Antiviral Agents; Betacoronavirus; Chlorocebus aethiops; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Combinations; Emetine; Epithelial Cells; Homoharringtonine; Humans; Lopinavir; Pandemics; Pneumonia, Viral; Pyrazines; Ribavirin; SARS-CoV-2; Vero Cells; Virus Replication	2020
SARS-CoV-2: Recent Reports on Antiviral Therapies Based on Lopinavir/Ritonavir, Darunavir/Umifenovir, Hydroxychloroquine, Remdesivir, Favipiravir and other Drugs for the Treatment of the New Coronavirus. Current medicinal chemistry, 2020, Volume: 27, Issue:27 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Betacoronavirus; China; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Darunavir; Drug Combinations; Humans; Hydroxychloroquine; Indoles; Lopinavir; Pandemics; Pneumonia, Viral; Pyrazines; Ritonavir; SARS-CoV-2	2020
Case 17-2020: A 68-Year-Old Man with Covid-19 and Acute Kidney Injury. The New England journal of medicine, 2020, May-28, Volume: 382, Issue:22 Topics: Acute Kidney Injury; Adenosine Monophosphate; Aged; Alanine; Amides; Anti-Inflammatory Agents; Anticoagulants; Antiviral Agents; Betacoronavirus; Continuous Renal Replacement Therapy; Coronavirus Infections; COVID-19; Creatinine; Humans; Hypertension; Lung; Male; Obesity; Pandemics; Pneumonia, Viral; Pyrazines; Radiography, Thoracic; SARS-CoV-2	2020
Potential Repurposed Therapeutics and New Vaccines against COVID-19 and Their Clinical Status. SLAS discovery : advancing life sciences R & D, 2020, Volume: 25, Issue:10 Topics: Adenosine Monophosphate; Alanine; Amides; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antiviral Agents; Chloroquine; Clinical Trials as Topic; COVID-19; COVID-19 Drug Treatment; COVID-19 Vaccines; Cyclopropanes; Drug Evaluation, Preclinical; Drug Repositioning; Humans; Isoindoles; Lactams; Lactams, Macrocyclic; Mice, Transgenic; Proline; Pyrazines; SARS-CoV-2; Small Molecule Libraries; Sulfonamides; Vaccines, Synthetic	2020
Interactions Between Remdesivir, Ribavirin, Favipiravir, Galidesivir, Hydroxychloroquine and Chloroquine with Fragment Molecular of the COVID-19 Main Protease with Inhibitor N3 Complex (PDB ID:6LU7) Using Molecular Docking. Journal of nanoscience and nanotechnology, 2020, 12-01, Volume: 20, Issue:12 Topics: Adenine; Adenosine; Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Betacoronavirus; Binding Sites; Chloroquine; Coronavirus 3C Proteases; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cysteine Endopeptidases; Drug Interactions; Humans; Hydrogen Bonding; Hydroxychloroquine; Ligands; Molecular Docking Simulation; Nanotechnology; Pandemics; Pneumonia, Viral; Protease Inhibitors; Pyrazines; Pyrrolidines; Ribavirin; SARS-CoV-2; Static Electricity; Viral Nonstructural Proteins	2020
Antiviral activity and safety of remdesivir against SARS-CoV-2 infection in human pluripotent stem cell-derived cardiomyocytes. Antiviral research, 2020, Volume: 184 Topics: Adenosine Monophosphate; Alanine; Amides; Animals; Antimalarials; Antiviral Agents; Chlorocebus aethiops; Chloroquine; COVID-19; COVID-19 Drug Treatment; Electrocardiography; Flow Cytometry; Heart Diseases; Humans; Hydroxychloroquine; Microscopy, Fluorescence; Myocytes, Cardiac; Pluripotent Stem Cells; Pyrazines; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; SARS-CoV-2; Vero Cells; Viral Plaque Assay	2020
Scientists criticize use of unproven COVID drugs in India. Nature, 2020, Volume: 587, Issue:7833 Topics: Adenosine Monophosphate; Alanine; Amides; Antibodies, Monoclonal, Humanized; Clinical Trials, Phase III as Topic; Controlled Clinical Trials as Topic; COVID-19; COVID-19 Drug Treatment; Drug Approval; Drug Repositioning; Drugs, Investigational; Humans; Hydroxychloroquine; India; Patient Safety; Placebos; Pyrazines; Reproducibility of Results; SARS-CoV-2; Time Factors; United States; Virus Shedding	2020
Gender differences in treatment of Coronavirus Disease-2019. Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2020, Dec-03, Volume: 90, Issue:4 Topics: Adenosine Monophosphate; Adult; Aged; Alanine; Amides; Antimalarials; Antiviral Agents; Cardiovascular Diseases; Chloroquine; Clinical Trials as Topic; Combined Modality Therapy; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; Diabetes Complications; Female; Humans; Hypertension; Immunity; Immunization, Passive; Immunoglobulins; Lopinavir; Male; Middle Aged; Mortality; Pandemics; Pyrazines; Ritonavir; SARS-CoV-2; Sex Characteristics	2020
[Clinical progression of the first wave of novel coronavirus infection in Ostrava]. Klinicka mikrobiologie a infekcni lekarstvi, 2020, Volume: 26, Issue:3 Topics: Adenosine Monophosphate; Aged; Alanine; Amides; COVID-19; Czech Republic; Female; Humans; Hydroxychloroquine; Length of Stay; Male; Pyrazines; Respiration, Artificial	2020
Simultaneous quantification of seven repurposed COVID-19 drugs remdesivir (plus metabolite GS-441524), chloroquine, hydroxychloroquine, lopinavir, ritonavir, favipiravir and azithromycin by a two-dimensional isotope dilution LC-MS/MS method in human serum Journal of pharmaceutical and biomedical analysis, 2021, Mar-20, Volume: 196 Topics: Adenosine; Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Azithromycin; Chloroquine; Chromatography, Liquid; COVID-19; COVID-19 Drug Treatment; Furans; Humans; Hydroxychloroquine; Isotopes; Lopinavir; Pandemics; Pyrazines; Pyrroles; Ritonavir; SARS-CoV-2; Tandem Mass Spectrometry; Triazines	2021
In silico evaluation of potential inhibitory activity of remdesivir, favipiravir, ribavirin and galidesivir active forms on SARS-CoV-2 RNA polymerase. Molecular diversity, 2022, Volume: 26, Issue:1 Topics: Adenine; Adenosine; Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; COVID-19 Drug Treatment; Drug Repositioning; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Pyrazines; Pyrrolidines; Ribavirin; RNA, Viral; SARS-CoV-2	2022
Prolonged persistence of SARS-CoV-2 infection during A+AVD therapy for classical Hodgkin's lymphoma: A case report. Current problems in cancer, 2021, Volume: 45, Issue:6 Topics: Adenosine Monophosphate; Adult; Alanine; Amides; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Brentuximab Vedotin; COVID-19; COVID-19 Drug Treatment; COVID-19 Nucleic Acid Testing; Dacarbazine; Disease Progression; Doxorubicin; Hodgkin Disease; Humans; Male; Pregnenediones; Pyrazines; Time Factors; Vinblastine	2021
Japan's Drug Regulation During the COVID-19 Pandemic: Lessons From a Case Study of Favipiravir. Clinical pharmacology and therapeutics, 2022, Volume: 111, Issue:3 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Clinical Trials, Phase III as Topic; COVID-19; COVID-19 Drug Treatment; Dexamethasone; Double-Blind Method; Drug Approval; Humans; Japan; Pyrazines	2022
Cardiovascular Considerations of Remdesivir and Favipiravir in the Treatment of COVID-19. Cardiovascular & hematological disorders drug targets, 2021, Volume: 21, Issue:2 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; COVID-19 Drug Treatment; Heart Diseases; Humans; Pyrazines; SARS-CoV-2	2021
Retrospective evaluation of seven different treatment protocols in hospitalized COVID-19 patients Turkish journal of medical sciences, 2021, 12-13, Volume: 51, Issue:6 Topics: Adenosine Monophosphate; Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Amides; Antiviral Agents; Clinical Protocols; COVID-19; COVID-19 Nucleic Acid Testing; Female; Humans; Hydroxychloroquine; Length of Stay; Male; Middle Aged; Oseltamivir; Pandemics; Pyrazines; Respiration, Artificial; Retrospective Studies; SARS-CoV-2; Treatment Outcome; Young Adult	2021
Can the Antivirals Remdesivir and Favipiravir Work Better Jointly? In Silico Insights. Drug research, 2022, Volume: 72, Issue:1 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; COVID-19 Drug Treatment; Humans; Pyrazines; SARS-CoV-2	2022
Effect of drug metabolism in the treatment of SARS-CoV-2 from an entirely computational perspective. Scientific reports, 2021, 10-07, Volume: 11, Issue:1 Topics: Adenine; Adenosine; Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Chloroquine; COVID-19; COVID-19 Drug Treatment; Drug Design; Drug Discovery; Humans; Metabolic Networks and Pathways; Molecular Docking Simulation; Nitro Compounds; Pyrazines; Pyrrolidines; Ribavirin; SARS-CoV-2; Thiazoles	2021
Comparative assessment of favipiravir and remdesivir against human coronavirus NL63 in molecular docking and cell culture models. Scientific reports, 2021, 12-06, Volume: 11, Issue:1 Topics: Adenosine Monophosphate; Alanine; Amides; Animals; Antiviral Agents; Binding Sites; Cell Culture Techniques; Cell Line; Coronavirus NL63, Human; Haplorhini; Humans; Molecular Docking Simulation; Pyrazines; RNA-Dependent RNA Polymerase; Virus Replication	2021
Drug-Membrane Interactions: Effects of Virus-Specific RNA-Dependent RNA Polymerase Inhibitors Remdesivir and Favipiravir on the Structure of Lipid Bilayers. Biochemistry, 2022, 07-05, Volume: 61, Issue:13 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; COVID-19 Drug Treatment; Humans; Lipid Bilayers; Pyrazines; RNA-Dependent RNA Polymerase; SARS-CoV-2	2022
Insights on the Quantitative Concurrent Fluorescence-Based Analysis of Anti-COVID-19 Drugs Remdesivir and Favipiravir. Journal of fluorescence, 2022, Volume: 32, Issue:5 Topics: Adenosine Monophosphate; Alanine; Amides; COVID-19 Drug Treatment; Humans; Pandemics; Pyrazines; SARS-CoV-2	2022
Spectrofluorimetric quantitative analysis of favipiravir, remdesivir and hydroxychloroquine in spiked human plasma. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2022, Nov-15, Volume: 281 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Pyrazines; SARS-CoV-2; Spectrometry, Fluorescence	2022
Virtual Screening and Quantum Chemistry Analysis for SARS-CoV-2 RNA-Dependent RNA Polymerase Using the ChEMBL Database: Reproduction of the Remdesivir-RTP and Favipiravir-RTP Binding Modes Obtained from Cryo-EM Experiments with High Binding Affinity. International journal of molecular sciences, 2022, Sep-20, Volume: 23, Issue:19 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; COVID-19 Drug Treatment; Cryoelectron Microscopy; Humans; Molecular Docking Simulation; Nucleosides; Polyphosphates; Pyrazines; Reproduction; Ribonucleosides; RNA-Dependent RNA Polymerase; RNA, Viral; SARS-CoV-2	2022
Competitive Formation of 2,3-Butanedione and Pyrazines through Intervention of Added Cysteine during Thermal Processing of Alanine-Xylose Amadori Compounds. Journal of agricultural and food chemistry, 2022, Dec-07, Volume: 70, Issue:48 Topics: Alanine; Cysteine; Pyrazines; Xylose	2022
Cysteine-Induced pH-Dependent Formation of Thiols and Sulfides or 2-Acetylthiazole and Pyrazines during Thermal Treatment of Journal of agricultural and food chemistry, 2023, Feb-08, Volume: 71, Issue:5 Topics: Alanine; Cysteine; Hydrogen-Ion Concentration; Maillard Reaction; Pyrazines; Sulfhydryl Compounds; Sulfides; Xylose	2023