alanine has been researched along with proline in 1228 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 554 (45.11) | 18.7374 |
1990's | 169 (13.76) | 18.2507 |
2000's | 309 (25.16) | 29.6817 |
2010's | 138 (11.24) | 24.3611 |
2020's | 58 (4.72) | 2.80 |
Authors | Studies |
---|---|
Boxer, PA; Bruns, RF; Drummond, JT; Johnson, G | 1 |
Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
Brandsch, M; Gebauer, S; Laug, L; Schäfer, S; Thondorf, I; Voigt, V; Zebisch, K | 1 |
Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S | 1 |
Burrill, PH; Lerner, J; Sattelmeyer, PA | 1 |
Lim, DV; Qadri, SM; Williams, RP | 1 |
Jayaraman, K; Manoharan, TH | 1 |
Chen, RF; Maly, M; Smith, PD | 1 |
Kutzman, RS; Roberts, JF | 1 |
Długoński, J; Jaworski, A; Sedlaczek, L; Wilmańska, D | 1 |
Fryer, TF; Mead, GC | 1 |
Kurelec, B | 1 |
Lee, SG; Lipmann, F; Littau, V | 1 |
Blass, JP; Hansen, S; Haworth, JC; Perry, TL; Urquhart, N | 1 |
Fukui, S; Hayakawa, K; Kanai, K; Kusaka, I | 1 |
Lee, SG; Lipmann, F | 1 |
Fischer, MH; Fortune, JS; Foster, SH; Gilbert, EF | 1 |
Cronholm, T | 1 |
Bisschop, A; de Jong, L; Konings, WN; Lima Costa, ME | 1 |
Pate, JL; Porter, JS | 1 |
Lim, DV; Nichols, C; Qadri, SM; Williams, RP | 1 |
Ashman, PU; Newport, GR; Page, CR; Seed, JR; Stibbs, HH | 1 |
Miller, JJ; Steele, SD | 1 |
Greco, GM; Magli, A | 1 |
James, AN; Lim, DV; Williams, RP | 1 |
Bater, AJ; Venables, WA | 1 |
Brenschede, G; Quecke, W; Schwartz, AC | 1 |
Devenyi, R; Israel, Y; Orrego, H; Tiefenbach, H; Varghese, G | 1 |
Balaram, P; Venkatachalapathi, YV | 1 |
Fasman, GD; Schwartz, AM | 1 |
Davidson, CS; Fernstrom, JD; Hammarstrom-Wiklund, B; Munro, HN; Rand, WM; Wurtman, RJ | 1 |
Borghetti, AF; Guidotti, GG; Tramacere, M | 1 |
Bailey, RS; Fried, B | 1 |
Mestyán, J; Schultz, K; Soltész, G | 1 |
Dall'asta, V; Gazzola, GC; Guidotti, GG | 2 |
McNamara, PD; Reynolds, R; Segal, S | 1 |
Alekseenko, LP; Orekhovich, VN; Pozdnev, VF; Zolotov, NN | 1 |
Hertz, L; Krogsgaard-Larsen, P; Schousboe, A; Svenneby, G | 1 |
Beccaria, L; Chiumello, G; Gianazza, E; Luppis, B; Righetti, PG | 1 |
Schoffeniels, E | 1 |
Qadri, SM; Scott, RH; Williams, RP | 1 |
Rapport, EW | 1 |
Anda, LP; Dotchev, D; Liappis, N | 1 |
Kafatos, FC; Petri, WH; Wyman, AR | 1 |
Deutsch, HF; Fett, JW | 1 |
Ferber, S; Richardson, FS | 1 |
Gaull, GE; Heinonen, K; Räih, NC; Rassin, DK | 1 |
Iwase, H; Murai, A | 1 |
Jagenburg, R; Jonsson, O; Lundholm, K; Lundstam, S; Nauclér, J; Pettersson, S; Scherstén, T | 1 |
Costilow, RN | 2 |
Fisher, FM; Jackson, PR | 1 |
Berg, A; Keul, J | 1 |
Gupta, MK; Gupta, VD | 1 |
Bhatnagar, RS; Rapaka, RS | 2 |
Grathwohl, C; Wüthrich, K | 3 |
Bachra, BN | 1 |
Mitra, AK; Ramachandran, GN | 1 |
Horváth, M; Mestyán, J; Schultz, K; Soltész, G | 2 |
Lowe, NR; Robinson, C; Weatherell, JA | 1 |
Hayes, ML; Hyatt, AT | 1 |
Wheeler, DD | 1 |
F-entes, M; Kaczorowski, G; Shaw, L; Walsh, C | 1 |
Lee, M; Oxender, DL; Robbins, JC | 1 |
Hkkinen, HM; Kulonen, E | 1 |
Trayhurn, P | 1 |
Tometsko, AM; Vogelstein, E | 1 |
Baños, G; Daniel, PM; Moorhouse, SR; Pratt, OE | 1 |
Dessauer, PL; Hubbard, M; Huisman, TH; Lindeman, JG; Wilson, JB; Winton, EF; Wrightstone, RN | 1 |
Havran, RT; Roy, J; Schwartz, IL; Walter, R | 1 |
Asch, HL; Read, CP | 1 |
Anthony, WL; Hsu, JM; Rider, AA | 1 |
Eisenbach, GM; Stolte, H; Weise, M | 1 |
Ivano, E; Kr"steva, A; Lozanova, L; Nedkov-Bratanova, N; Nikolov, N | 1 |
Hansford, RG; Johnson, RN | 1 |
Fendler, JH; Nagyvary, J; Nome, F | 1 |
Guadalix, FJ; Ruiz, MC | 1 |
Kester, AS; Mayfield, DC | 1 |
Benassi, CA; Guggi, A; Rocchi, R; Salvadori, S; Tomatis, R | 1 |
di Iorio, EE; Lehmann, H; Lorkin, PA; Marti, HR; Winterhalter, KH | 1 |
Gerig, JT; McLeod, RS | 1 |
Claybrook, DL | 1 |
Morrow, G; Revsin, B | 1 |
Jaenicke, R; Risse, B; Rudolph, R; Schumacher, G; Stempfer, G | 1 |
Boutron, A; Goenner, S; Lemonnier, A; Moatti, N; Soni, T | 1 |
Akino, T; Konno, R; Nagata, Y; Shimojo, T; Yamamoto, K; Yasumura, Y | 1 |
Bögl, KW; Dehne, LI; Fritz, P; Zagon, J | 1 |
Akino, T; Masui, R; Nagata, Y | 1 |
Maenz, DD; Patience, JF | 1 |
Kelly, AF; Kroll, RG; Patchett, RA | 1 |
Nagarajaram, HA; Paul, PK; Ramakrishnan, C; Ramanarayanan, K; Soman, KV | 1 |
Nagata, Y; Shimojo, T; Yamamoto, K | 1 |
Hiraga, K; Ito, W; Miles, EW; Ogasahara, K; Yutani, K | 1 |
Dempsey, CE | 1 |
Bursey, MM; Schwartz, BL | 1 |
Anderson, AG; Hermans, J; Yun, RH | 1 |
Caprio, J; Wegert, S | 1 |
Barrett, AJ; Knight, CG | 1 |
Ivanoff, LA; Langlois, AJ; Looney, DJ; Matthews, TJ; McDanal, C; Morris, JF; Petteway, SR; Wong-Staal, F | 1 |
Celma, C; Giralt, E | 1 |
Fuchs, JA; Langsetmo, K; Woodward, C | 1 |
Anderson, A; Hermans, J; Yun, RH | 1 |
Carrell, RW; Daly, M; Harper, PL; Perry, DJ; Price, J; Tait, RC; Walker, ID | 1 |
Amioka, H; Dojo, S; Hayashi, K; Hiraoka, M; Hirata, Y; Kurushima, H; Nakashima, K; Nishio, E; Ohtani, H; Saeki, M | 1 |
Aguirre, J; Arteman, P; Brandariz, S; del Castillo, E; Silberstein, C; Uranga, J | 1 |
Rogers, QR; Spensley, MS; Willits, NH; Zicker, SC | 1 |
Barbato, G; Bax, A; Ikura, M; Kay, LE; Krinks, M; Spera, S | 1 |
Rölla, G; Rykke, M; Sönju, T | 1 |
Béliveau, R; Demeule, M; Jetté, M; Potier, M | 1 |
Felipe, A; Remesar, X; Viñas, O | 1 |
Hayashi, S; Ogasahara, K; Sugisaki, Y; Yutani, K | 1 |
Bazzo, R; Boheim, G; Campbell, ID; Dempsey, CE; Harvey, TS; Syperek, I | 1 |
Bussolati, O; Dall'Asta, V; Gazzola, GC; Rotoli, BM | 1 |
Baldwin, RL; Robertson, AD; Strehlow, KG | 1 |
Dobbins, DE; Premen, AJ | 1 |
Gooley, PR; MacKenzie, NE | 1 |
Cohen, P; Donella Deana, A; Mac Gowan, CH; Marchiori, F; Meyer, HE; Pinna, LA | 1 |
McCleary, WR; Zusman, DR | 1 |
Bajaj, SP; Birktoft, JJ; Kasper, CK; Kuppuswamy, MN; Saini, R; Spitzer, SG | 1 |
Koshy, TI; Luntz, TL; Margoliash, E; Schejter, A | 1 |
Adibi, SA; Lochs, H; Morse, EL | 1 |
Dodt, J; Köhler, S; Schmitz, T; Wilhelm, B | 1 |
Baquet, A; Hue, L; Meijer, AJ; Plomp, PJ; van Woerkom, GM | 1 |
Abillon, E; Bremier, L; Cardinaud, R | 1 |
Bailey, JM; Brandts, JF; Lin, LN; Mas, MT | 1 |
Alexandrou, EN; Liakopoulou-Kyriakides, M | 1 |
Brodin, P; Drakenberg, T; Forsén, S; Grundström, T; Johansson, C; Thulin, E | 1 |
Beyreuther, K; Dimroth, P; Oesterhelt, D; Reinke, H; Schwarz, E | 1 |
Premen, AJ | 1 |
Pajor, AM; Wright, SH | 2 |
Hundal, HS; Rennie, MJ; Watt, PW | 1 |
Chao, BH; Khorana, HG; Mogi, T; Stern, LJ | 1 |
Chenoweth, M; Dunn, A; Said, HM | 1 |
Katz, J | 1 |
Ahl, PL; Khorana, HG; Mogi, T; Rothschild, KJ; Stern, LJ | 1 |
Blouquit, Y; Galacteros, F; Gombaud-Saintonge, G; Riou, J; Wajcman, H | 1 |
Hu, H; Huisman, TH; Kutlar, A; Kutlar, F; Ozsahin, H; Ulukutlu, L; Webber, BB; Wilson, JB | 1 |
Bushuev, VN; Gudkov, AT; Liljas, A; Sepetov, NF | 1 |
Konisky, J; Sment, KA | 1 |
Cassano, G; Storelli, C; Vilella, S | 1 |
Carrell, RW; Daly, M; Fairham, S; Harper, PL; Perry, DJ | 1 |
Miura, R; Miyake, Y; Nishina, Y; Shiga, K; Tojo, H; Watari, H | 1 |
Lowe, PN; Rowe, AF | 1 |
Miura, R; Miyake, Y | 1 |
Moriyama, A; Nakanishi, M; Sasaki, M; Takenaka, O | 1 |
Arme, C; Jeffs, SA | 2 |
Forni, C; Halsey, MJ; Rostain, JC; Wardley-Smith, B | 1 |
Sidhu, HS; Wood, JD | 1 |
Christensen, HN; Flickinger, KS; Pisoni, RL; Thoene, JG | 1 |
deBruyn, B; Saz, HJ; Srivastava, VM | 1 |
Guest, JR; Miles, JS; Perham, RN; Radford, SE | 1 |
Kelley, RF; Richards, FM | 1 |
Distler, W; Kagermeier, A | 1 |
Fukagawa, NK; Minaker, KL; Rowe, JW; Young, VR | 1 |
Atkins, JF; Dayhuff, TJ; Gesteland, RF | 1 |
Dennis, BJ; Kerr, DI; Krantis, A | 1 |
Bhandari, DG; Levine, BA; Trayer, IP; Yeadon, ME | 1 |
Curtis, MA; Thompson, J; Wittenberger, CL | 1 |
Frick, L; Wolfenden, R | 1 |
Randell, SH; Sannes, PL | 1 |
He, SG; Shen, K; Zang, XY | 1 |
Dingwall, C | 1 |
Bobyleva-Guarriero, V; Lardy, HA | 1 |
Nakatani, T; Ozawa, K; Yasuda, K | 1 |
Fiat, D; Gotsis, ED; Spisni, A | 1 |
Hayasaka, H; Ishida, K; Totsuka, M | 1 |
Asano, M; Jikko, A; Kamiyama, Y; Kimura, K; Ozawa, K; Tobe, T; Ukikusa, M; Yamato, T | 1 |
Belzberg, H; Coleman, B; Pittiruti, M; Placko, R; Sganga, G; Siegel, JH; Wedel, S; Wiles, CE | 1 |
Foreman, JW; Ginkinger, K; McNamara, PD; Pepe, LM; Segal, S | 1 |
Gilles, R | 1 |
Kelly, B; Levy, JG | 1 |
Karlsson, JO; Sjöstrand, J | 1 |
Mozes, E; Sela, M; Shearer, GM | 1 |
Mozes, E; Sela, M; Shearer, GM; Taussig, MJ | 2 |
Bryce, GF | 1 |
Mozes, E; Schwartz, M; Sela, M | 1 |
Lin, CM; Wagner, C | 1 |
McClure, WO; Schlichter, DJ | 1 |
Bonavida, B; Mozes, E; Sela, M; Shearer, GM | 1 |
Adams, E; Heacock, AM | 1 |
Burrill, P; Lerner, J; Miller, DS | 1 |
Bradshaw, RP; Perkins, RR; Pincock, RE | 1 |
Bentley, PH; Gregory, RA; Grossman, MI; Tracy, HJ | 1 |
Diamond, S; Hansen, S; Perry, TL; Stedman, D | 1 |
Boos, W; Shen, BH | 1 |
Qadri, SM; Williams, RP | 1 |
Dotchev, D; Hungerland, H; Liappis, N; Oyanagi, K | 1 |
Casey, R; Lehmann, H; Outeirino, J; White, JM | 1 |
Banerjee, AB; Bhattacharyya, SK | 1 |
Joshi, PC; Pathak, HD | 1 |
Hansen, S; Lesk, D; Perry, TL | 1 |
Boyer, PD; Klein, WL | 1 |
Berger, M; Ruderman, NB | 1 |
Allen, DW | 1 |
Baranova, AM; Bragina, MP; Moroz, AF | 1 |
Manahan, J; Mandl, I | 3 |
Costilow, RN; Laycock, L | 1 |
Albrecht, I; Hillman, RE; Rosenberg, LE | 1 |
Hillman, RE; Rosenberg, LE | 1 |
Froncish, W; Kalmanson, AE; Kharitonenkov, IG; Yuferov, VP | 1 |
Costilow, RN; Dyer, JK | 2 |
DeFeudis, FV; Delgado, JM; Roth, RH | 1 |
Lanks, KW; Weinstein, IB | 1 |
Blake, J; Li, CH; Wang, KT | 1 |
Shallenberger, MK; Simoni, RD | 1 |
Christensen, HN | 1 |
Ferreira, SH; Greene, LJ; Stewart, JM | 1 |
Bennett, JP; Mulder, AH; Snyder, SH; Young, AB | 1 |
Beutler, E; Lang, A; Lehmann, H | 1 |
Derevitskaya, VA; Kochetkov, NK; Likhosherstov, LM; Medvedev, SA | 1 |
Crippa, PR; Tedeschi, RA; Vecli, A | 1 |
Mulder, AH; Snyder, SH | 1 |
Mani, UV; Radhakrishnan, AN | 1 |
Ikenaka, T; Murao, S; Nabeshima, Y; Odani, S; Sakai, M; Sato, S | 1 |
Anderer, FA; Wittmann, HG; Wittmann-Liebold, B | 1 |
Bumpus, FM; Chaturvedi, NC; Khosla, MC; Smeby, RR | 1 |
Nishikimi, M; Oishi, N; Takai, A; Yagi, K | 2 |
Krvavica, S; Martincic, T | 1 |
Abeles, RH; Schonbrunn, A; Walsh, CT | 1 |
Lund, P | 1 |
Lewis, GP; McMartin, C; Rosenthal, SR; Yates, C | 1 |
Fraser, KJ; Haber, E; Pulsen, K | 1 |
Reizin, FN; Zeitlenok, NA | 1 |
Hellebust, JA; Liu, MS | 2 |
Asafov, GB; Ekisenina, NI; Ivanova, LM; Lumel'skiĭ, VIa; Smagin, VG | 1 |
Dancis, J; Schneider, H | 1 |
Lindig, OH; Mitlin, N; Thompson, AC; Wiygul, G | 1 |
Shotts, WJ; Sievers, AJ | 1 |
Crossley, AC; Evans, PD | 1 |
el-Sewefy, AZ; Hegazi, SM | 1 |
Palau, J; Puigdoménech, P | 1 |
Anandaraj, MP; Cherayil, JD | 1 |
Alderson, NE; Amos, HE; Boling, JA; Ely, DG; Goshtasbpour-Parsi, BG | 1 |
Sjöström, H | 1 |
Arai, T; Ichishima, E | 1 |
Davis, SR; Mepham, TB | 1 |
Friedmann, N; Miller, SL; Ring, D; Wolman, Y | 1 |
Shotton, DM; Watson, HC; White, NJ | 1 |
Wright, EM | 1 |
Arnon, R; Maron, E; Mozes, E; Sela, M; Shearer, GM | 1 |
Markussen, J; Sundby, F | 1 |
Kreil, G | 1 |
Miller, EJ | 1 |
Sunde, ML | 1 |
Amoss, MS; Anderson, HA; Monahan, MW; Vale, W | 1 |
Gylfe, E | 1 |
Quadri, SM; Williams, RP | 1 |
Frimpter, GW | 1 |
Christensen, HN; Quay, S | 1 |
Halpern, YS | 1 |
Griffin, GJ; Pass, T | 1 |
Abrahamsson, L; Hakelius, L; Hambraeus, L; Hjorth, G; Ohlin, SE | 1 |
Fekl, W | 1 |
Feng, HW; Pan, MW; Riggs, TR | 1 |
Steiner, DF; Tager, HS | 1 |
Flory, B; Krassner, SM | 2 |
Albers, RJ; DeTar, DF; Gilmore, F | 1 |
Evered, DF | 1 |
Alimov, IIu; Iur'eva, EA; Marchenko, ZM | 1 |
Belusko, RJ; Bruce, JI; Ruff, MD; Werner, JK | 1 |
Ando, T; Suzuki, K | 2 |
Fairweather, R; Jones, JH | 2 |
Okano, T; Sato, Y | 1 |
Tobin, MC | 1 |
Cheeseman, CI; Smyth, DH | 1 |
Aranda, JV; Colle, E; Papageorgiou, A; Reisner, SH; Schiff, D; Scriver, CR; Stern, L | 1 |
Gruber, L; Harris, JE | 1 |
Eastoe, JE; Martens, P; Thomas, NR | 1 |
Kopple, JD; Shinaberger, JH; Swendseid, ME; Umezawa, CY | 1 |
Bassett, RA; Chain, EB; Corbett, K | 2 |
Brown, PC; Glynn, LE | 1 |
Blout, ER; Thompson, RC | 4 |
Thompson, RC | 1 |
Harrap, BS; Heidemann, ER; Schiele, HD | 1 |
Isomoto, A; Shiga, K | 1 |
Aprison, MH; Freeman, AR; Graham, LT; McBride, WJ | 1 |
De Loecker, W; Stas, ML | 1 |
Herbert, JD | 1 |
Boullin, DJ; Crampton, RF; Heading, CE; Pelling, D | 1 |
Trayhurn, P; van Heyningen, R | 2 |
Hook, DJ; Vining, LC | 1 |
Josefsson, L; Norén, O; Sjöström, H | 1 |
Bowman, IB; Ford, WC | 1 |
Krassner, SM; Munson, KB; Sylvester, D | 1 |
Gruhn, K | 1 |
Cole, RD; Colom, J; Cozcolluela, C; Phelan, JJ; Subirana, JA | 1 |
De Coen, JL; Ralston, E | 1 |
Aprison, MH; Freeman, AR; McBride, WJ; Shank, RP | 1 |
Blake, RL; Grillo, RV; Russell, ES | 1 |
Jörnvall, H; Ohlsson, H; Philipson, L | 1 |
Bergström, J; Fürst, P; Norée, LO; Vinnars, E | 1 |
Cutler, RW; Dudzinski, DS | 1 |
Bayley, PM; Hooker, TM; Radding, W; Schellman, JA | 1 |
Urry, DW | 1 |
Kilejian, A | 2 |
Bergeron, M; Dubord, L | 1 |
Gröger, D; Johne, S | 1 |
Addison, JM; Burston, D; Matthews, DM | 1 |
Tonelli, AE | 1 |
De Luca, F; Macaione, S; Ruggeri, P; Tucci, G | 1 |
Kolaskar, AS; Ramachandran, GN; Ramakrishnan, C; Sasisekharan, V | 1 |
Doores, L; Schulman, JD; Silagi, S; Wrathall, JR | 1 |
Koehn, PV; Perlmann, GE | 1 |
Iwatani, A; Izui, K; Katsuki, H; Nishikido, T; Tanaka, S | 1 |
Freeman, HC | 1 |
Alvino, CG; Ingram, VM; Remington, L | 1 |
Ramachandran, GN; Venkatachalam, CM | 1 |
Degani, Y; Patchornik, A; Spande, TF; Witkop, B | 1 |
Cerná, J; Chládek, S; Pulkrábek, P; Rychlík, I; Zemlicka, J | 1 |
Gott, CL; Qadri, SM; Williams, RP | 1 |
Roy, AK | 1 |
Hunt, DE | 2 |
Glenner, GG; Nagatsu, I; Nagatsu, T | 1 |
Dolif, D; Jürgens, P | 4 |
Kinoshita, Y; Nemoto, G; Ujiie, A | 1 |
Gronlund, AF; Kay, WW | 1 |
Cahill, CF; Felig, P; Marliss, E; Ohman, JL | 1 |
Vinnars, E | 1 |
Bowers, C; Chang, JK; Currie, B; Folkers, K; Sievertsson, H | 1 |
Fekl, W; Lang, K | 1 |
Madison, V; Schellman, J | 1 |
Christian, JH; Hall, JM | 1 |
Franchi, R; Gazzola, GC; Guidotti, GG; Ronchi, P; Saibene, V | 1 |
Christiansen, PA; Reiser, S | 2 |
Cann, JR | 1 |
Hahn, K; Jesdinsky, HJ; Ladner, HA | 1 |
Dotchev, D; Hungerland, H; Liappis, N | 1 |
Boling, JA; Bradley, NW; Willard, JC | 1 |
Pan, MW; Riggs, TR | 1 |
Clark, KG; Lehmann, H; Lorkin, PA; Wiltshire, BG | 1 |
Hochachka, PW; Mustafa, T | 1 |
Dymicky, M; Mellon, EF; Naghski, J | 1 |
Oltjen, RR; Slyter, LL; Williams, EE; Wilson, RL | 1 |
Beaty, C; Becker, B; Coben, LA; Cotlier, E | 2 |
Morishita, S; Muramatsu, K; Odagiri, H; Takeuchi, H | 1 |
Ono, T; Tasaki, I | 1 |
Craft, IL; Peters, TJ | 1 |
Campbell, DJ; Reid, DW; Yakymyshyn, LY | 1 |
Karabin, L; Szczepanowska, M; Szcześniak, T; Wituch, K | 1 |
Beaty, C; Becker, B; Cohen, LA; Cotlier, E | 1 |
Shearer, TR; Suttie, JW | 1 |
Faulstich, H; Goodman, M; Naider, F; Patel, DJ; Tonelli, AE; Wieland, T | 1 |
Christensen, HN; Koser, BH | 1 |
Hornig, D; Weber, F; Wiss, O | 1 |
Blout, ER; Doyle, BB; Lorenzi, GP | 1 |
Blout, ER; Doyle, BB; Lorenzi, GP; Traub, W | 1 |
Barooshian, AV; Harris, WG; Lautenschleger, MJ | 1 |
Ermol'eva, ZV; Kolosova, IV; Pokidova, NV | 1 |
Christner, PJ; Rosenbloom, J | 1 |
Ermol'eva, ZV; Kolosova, IV; Pasternak, NA; Pokidova, NV; Shenderovich, VA | 1 |
Hall, TC; Tao, KL | 1 |
Haufe, F; Haufe, U; Lubs, H; Machill, G | 1 |
Keith, HD; Lotz, B | 1 |
Beljanski, M; Vapaille, N | 1 |
Basmadjian, GP; Floss, HG; Minghetti, A; Spalla, C; Tcheng, M | 1 |
Kotelchuck, D; Scheraga, HA | 1 |
Faulcon, FM; Lee, WH; Regan, JD; Takeda, S; Vodopick, N | 1 |
Hellman, A; Hellman, KB; Martin, DH; Novelli, GD; Yang, WK | 1 |
Geisler, C; Höcker, P; Stacher, A; Wiser, M | 1 |
Gerron, GG; Howard, CH; Rudman, D; Vogler, WR | 1 |
Barlow, GB; Macleod, AJ; Snipe, RM | 1 |
Appella, E; Martin, RG; Voll, MJ | 1 |
Lee, YP; Ness, GC; Takahashi, T | 1 |
Matthews, DB | 1 |
Melvås, BW | 1 |
Ermol'eva, ZV; Pokidova, NV; Zhuravleva, TP | 1 |
Miller, EM; Oellermann, RA | 1 |
Blout, ER; Brown, FR; Carver, JP | 1 |
Becker, GE; Sasek, V | 1 |
Fuchs, G; Oepen, H; Oepen, I | 1 |
Brinster, RL | 1 |
Noguchi, J; Yamamoto, H | 1 |
Chen, DM; Harper, AE; Rogers, QR | 1 |
Berg, WE; Mertes, DH | 1 |
Lanks, KW | 1 |
Andries, JC; Schwartz, A; Walton, AG | 1 |
Levin, RJ | 1 |
De la Noüe, J | 1 |
Damiani, A; De Santis, P; Pizzi, A | 1 |
Ermol'eva, ZV; Evseenko, LK; Iulikova, EP; Kolosova, IV; Pasternak, NA; Pokidova, NV; Shenderovich, VA; Silaev, AB | 1 |
Setchell, BP; Tuck, RR; Waites, GM; Young, JA | 1 |
Bowman, RL; Ito, Y; Pisano, JJ; Tanimura, T | 1 |
Khan, N; Lindblad, BS; Rahimtoola, RJ | 1 |
Cohen, JS; Putter, I; Smith, JL; Vandenheuvel, WJ | 1 |
Czerniak, Z | 1 |
Grimble, RF; Whitehead, RG | 1 |
Lajtha, A; Sadasivudu, B | 1 |
Neuhoff, V; Weise, M | 1 |
Nobel, PS; Wang, CT | 1 |
A'Zary, E; Saifer, A; Schneck, L; Valenti, C | 1 |
Christensen, HN; Thomas, EL | 1 |
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Gebauer, M; Schiefner, A; Skerra, A; Walser, R | 1 |
Chan, JFW; Chen, H; Chen, Z; Deng, S; Du, Z; Lau, SY; Li, C; Li, X; Mok, BWY; Wang To, KK; Wang, P; Wong, YC; Woo, KF; Yuen, KY; Zhou, J | 1 |
Cohan, RA; Karami, E; Khodabakhsh, F; Khosravy, MS; Mehdizadeh, A; Salimian, M; Vafabakhsh, A | 1 |
Ajaz, SJ; Banday, AH; Shameem, SA | 1 |
Perišić, O | 1 |
Abella, JR; Antunes, D; Clementi, C; Jackson, K; Kavraki, LE; Lizée, G | 1 |
Feng, Q; Jiang, J; Lukman, M; Ruiz-Carrillo, D; Zhang, Y; Zhao, Y; Zhou, X | 1 |
Kobayashi, T; Kobayashi, W; Kumakura, K; Matsuoka, H; Takahashi, A | 1 |
Hu, Y; Hurst, B; Ma, C; Szeto, T; Tarbet, B; Wang, J | 1 |
du Preez, I; Loots, DT; Opperman, M; Ronacher, K; van Reenen, M; Walzl, G | 1 |
Colinet, H; Hasson, E; Kreiman, L; Mensch, J; Renault, D; Schilman, PE | 1 |
Cobb, MH; Taylor, CA | 1 |
Badran, AH; Chen, M; Crnković, A; Ding, Y; Hoffman, KS; Krieger, JR; Melnikov, S; Söll, D; Vargas-Rodriguez, O; Westhof, E | 1 |
Aburas, J; Brown, AEX; Fleming, AC; Gao, FB; Gendron, TF; Ghadge, G; Gu, Y; Islam, P; Kankel, MW; Kiskinis, E; Kratsios, P; Krishnan, G; Roos, RP; Sonobe, Y; Warren, EC | 1 |
Abbas, SN; Bhatti, S; Mahmood, N; Nasir, SB; Shahid, S | 1 |
Benjelloun, AT; Benzakour, M; El Adnani, Z; El Khabchi, M; Fitri, A; Lahlou, H; Mcharfi, M | 1 |
Del Rio, C; Gandhi, RT; Malani, PN | 1 |
Misra, A; Singh, A; Singh, AK; Singh, R | 1 |
Kozlov, M | 1 |
Bashir, A; Choudhary, MI; Ganesan, A; Jabeen, A; Karim, H; Khan, SN; Nadeem-Ul-Haque, M; Qayyum, S; Shah, ZA; Shaheen, F | 1 |
André, E; Chiu, W; De Jonghe, S; Jochmans, D; Leyssen, P; Maes, P; Neyts, J; Raymenants, J; Slechten, B; Vangeel, L | 1 |
Furusho, A; Hamase, K; Ishii, C; Kamarulzaman, A; Kamaruzzaman, SB; Lee, CS; Leong, KH; Mita, M; Rajasuriar, R; Shaharudin, S; Yap, SH; Zulhaimi, NS | 1 |
Bertram, HC; Dam, TV; Hansen, M; He, W; Thøgersen, R | 1 |
Hamase, K; Mita, M; Sasabe, J; Shimizu-Hirota, R; Suzuki, M | 1 |
Ledford, H | 1 |
Anjum Zia, M; Jahan, N; Kiran, S; Mujtaba, N; Naqvi, SAR; Sultana, B | 1 |
Byun, JK; He, SL; Jang, JC; Musier-Forsyth, K; Vu, JA | 1 |
Kim, M; Shin, HE; Won, CW | 1 |
Bi, Y; Chen, G; Chen, L; Chen, Y; Dai, M; Deng, H; Du, R; Gao, Z; Hu, C; Hu, R; Huo, Y; Lai, S; Li, D; Li, M; Li, Q; Lin, H; Liu, C; Liu, R; Lu, J; Luo, Z; Mu, Y; Ning, G; Qin, G; Qin, Y; Shen, F; Shi, L; Su, Q; Tang, X; Wan, Q; Wang, G; Wang, J; Wang, S; Wang, T; Wang, W; Wang, X; Wang, Y; Wu, S; Xu, G; Xu, M; Xu, Y; Yan, L; Yang, T; Ye, Z; Yu, X; Zhang, D; Zhang, Y; Zhao, J; Zhao, X; Zhao, Z; Zheng, R | 1 |
Akbari, V; Farrokhi, A; Ghobadi, S; Khodarahmi, R; Mehrabi, M; Mohammadi, S | 1 |
Bhattacharya, A; Chauhan, P; Dwivedi, A; Mishra, A; Pandey, S | 1 |
Ates, O; Toker, EB; Yesilbag, K | 1 |
De Grassi, A; Giangregorio, N; Incampo, G; Indiveri, C; Pierri, CL; Tonazzi, A; Tragni, V | 1 |
Gao, Y; Li, L; Li, Y; Xiu, M | 1 |
Shibuya, H; Shimizu, M | 1 |
Bhat, IA; Bhat, RAH; Dash, P; Ganie, PA; Gargotra, P; Nazir, MI; Siva, C; Tandel, RS; Yousuf, DJ | 1 |
Ding, T; Gao, L; Ge, J; Gu, Q; Ma, X; Shen, W; Wang, H; Xue, F; Zhang, X | 1 |
Jia, Y; Jiang, T; Li, S; Ren, Z; Wang, J; Wang, L; Wang, Z; Yu, Y | 1 |
Abu-Gharbieh, E; Abushawish, KYI; Al-Hroub, HM; Alzoubi, KH; Bustanji, Y; El-Huneidi, W; Elgendy, SM; Giddey, AD; Mousa, M; Omar, HA; Semreen, MH; Soares, NC; Soliman, SSM | 1 |
Binder, U; Friedrich, L; Kikuchi, Y; Matsuda, Y; Skerra, A | 1 |
Han, L; Jiang, B; Long, C; Xu, Y | 1 |
Brennan, L; Flatt, PR; Johnson, PRV; McClenaghan, NH; Moffett, RC; Tarasov, AI; Turbitt, J | 1 |
Karakirova, Y | 1 |
Ban, Q; Hou, YY; Huang, T; Ma, B; Shi, L; Zhang, ML; Zhang, Q; Zhou, YF | 1 |
Luo, D; Xu, X; Zhang, X | 1 |
Alias, H; Cheng, F; Duan, E; Li, B; Liu, Y; Maarof, H; Ren, H; Udin, SM; Yang, J; Zhang, Y; Zhou, W | 1 |
Hashemi, M; Moieni, A; Sabet, MS | 1 |
Farquhar, CE; Pentelute, BL; Rodriguez, J; Sato, K | 1 |
Chen, M; Gong, J; Han, D; Li, F; Wang, D; Wang, Y; Wei, J; Zhang, T; Zhou, L | 1 |
Nakamura, H; Oda-Ueda, N; Ohkuri, T; Yoshikawa, M | 1 |
Kong, PF; Liu, C; Liu, X; Yang, H; Zhang, J; Zhao, L; Zheng, Q | 1 |
Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
31 review(s) available for alanine and proline
Article | Year |
---|---|
[Eye manifestations of amino acid disorders].
Topics: Alanine; Albinism; Alkaptonuria; Amino Acid Metabolism, Inborn Errors; Child; Cystinosis; Cystinuria; Eye Diseases; Eye Manifestations; Glycine; Hartnup Disease; Hepatolenticular Degeneration; Homocystinuria; Humans; Lysine; Oculocerebrorenal Syndrome; Oxidoreductases; Phenylketonurias; Proline; Pyruvates | 1978 |
Adaptations with respect to salinity.
Topics: Adaptation, Physiological; Alanine; Amino Acids; Animals; Copper; Crustacea; Fresh Water; Glutamates; Glycolysis; L-Serine Dehydratase; Lactates; Models, Biological; Muscles; Oxygen Consumption; Proline; Seawater; Sodium Chloride; Water; Water-Electrolyte Balance | 1976 |
Mechanisms of integumental amino acid transport in marine bivalves.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Biomechanical Phenomena; Bivalvia; Cell Membrane; Gills; Histological Techniques; Lysine; Models, Biological; Proline; Sodium | 1989 |
Protein accumulation in the cell nucleus.
Topics: Alanine; Animals; Biological Transport; Cell Nucleus; Female; In Vitro Techniques; Lysine; Nuclear Proteins; Nucleoplasmins; Nucleoproteins; Oocytes; Pepsin A; Phosphoproteins; Proline; Xenopus laevis | 1985 |
On the development of amino acid transport systems.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Animals, Newborn; Arginine; Binding Sites; Biological Transport, Active; Chickens; Cyclic AMP; Cyclopentanes; Female; Glucagon; Glutamates; Glutamine; Glycine; Guinea Pigs; Intestinal Absorption; Kidney Cortex; Kidney Tubules; Liver; Lysine; Maternal-Fetal Exchange; Muscles; Myocardium; Pregnancy; Proline; Rats | 1973 |
A review of biochemical studies on the genetically distinct collagens of the skeletal system.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Bone and Bones; Cartilage, Articular; Collagen; Glutamates; Homoserine; Hydroxyproline; Leucine; Peptides; Phenylalanine; Proline; Rats; Serine; Threonine; Valine | 1973 |
Utilization of D- and DL- amino acids and analogs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Histidine; Isomerism; Keto Acids; Leucine; Methionine; Nutritional Requirements; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1972 |
Aminoacidurias due to inherited disorders of metabolism. 2.
Topics: Acidosis; Alanine; Amino Acid Metabolism, Inborn Errors; Arginase; Arginine; Carbamates; Citrulline; Dipeptides; Glutarates; Glycine; Histidine; Humans; Hydroxyproline; Hyperglycemia; Infant, Newborn; Keto Acids; Lysine; Malonates; Maple Syrup Urine Disease; Ornithine Carbamoyltransferase; Phosphotransferases; Proline; Sarcosine; Succinates; Urea; Valine | 1973 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Crystal structures of metal-peptide complexes.
Topics: Alanine; Aminobutyrates; Aspartic Acid; Binding Sites; Biureas; Cadmium; Chelating Agents; Computers; Copper; Crystallography; Dipeptides; Glutamates; Glycine; Histidine; Imidazoles; Mercury; Metals; Models, Chemical; Nickel; Penicillamine; Peptides; Proline; Silver; Stereoisomerism; Water; Zinc | 1967 |
Conformation of polypeptide chains.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Carboxypeptidases; Chemical Phenomena; Chemistry; Chymotrypsin; Collagen; Dipeptides; Esters; Fibroins; Glutamates; Glycine; Hemoglobins; Heterocyclic Compounds; Muramidase; Myoglobin; Oxytocin; Papain; Peptides; Proline; Ribonucleases; Statistics as Topic; Stereoisomerism; Sulfides; Tyrosine; Tyrothricin; Valine; Vasopressins; X-Ray Diffraction | 1969 |
Selective cleavage and modification of peptides and proteins.
Topics: Alanine; Aspartic Acid; Chemical Phenomena; Chemistry; Chymotrypsin; Cysteine; Glutamates; Glycine; Hydrogen-Ion Concentration; Methionine; Muramidase; Oxidation-Reduction; Peptides; Phenylalanine; Proline; Proteins; Pyrrolidines; Ribonucleases; Serine; Succinates; Threonine; Tryptophan | 1970 |
The impact of the amino-acid sequence on the specificity of copper(II) interactions with peptides having nonco-ordinating side-chains.
Topics: Alanine; Amino Acid Sequence; Copper; Glycine; Peptides; Proline; Protein Conformation | 1997 |
The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes.
Topics: Adult; Age of Onset; Aged; Alanine; Alleles; Blood Glucose; Blood Pressure; Body Mass Index; Cholesterol; Diabetes Mellitus, Type 2; Family Health; Fathers; Female; Genotype; Humans; Linkage Disequilibrium; Lipoproteins, HDL; Male; Middle Aged; Models, Genetic; Mothers; Phenotype; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Risk Factors; Transcription Factors | 2000 |
The peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism.
Topics: Adipocytes; Alanine; Amino Acid Substitution; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Humans; Insulin; Insulin Secretion; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2002 |
Effect of the peroxisome proliferator activated receptor-gamma gene Pro12Ala variant on body mass index: a meta-analysis.
Topics: Alanine; Body Mass Index; Cohort Studies; Coronary Artery Disease; Female; Genotype; Humans; Male; Obesity; Polymorphism, Single Nucleotide; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors; United Kingdom | 2003 |
[PPARgamma gene Pro12Ala polymorphism in diabetes mellitus].
Topics: Alanine; Alleles; Amino Acid Substitution; Animals; Diabetes Mellitus; Environment; Genetic Predisposition to Disease; Humans; Life Style; Pharmacogenetics; Polymorphism, Single Nucleotide; PPAR gamma; Proline | 2005 |
Ste20-type kinases: evolutionarily conserved regulators of ion transport and cell volume.
Topics: Alanine; Animals; Apoptosis; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Cycle; Cell Size; Homeostasis; Humans; Ion Transport; K Cl- Cotransporters; Nerve Tissue Proteins; Proline; Protein Kinases; Protein Serine-Threonine Kinases; Signal Transduction; Sodium-Potassium-Chloride Symporters; Symporters | 2006 |
Aquaporin subfamily with unusual NPA boxes.
Topics: Alanine; Amino Acid Sequence; Animals; Aquaporins; Asparagine; Biological Transport, Active; Molecular Sequence Data; Plant Proteins; Proline; Protein Structure, Tertiary; Water | 2006 |
Conformation of the backbone in unfolded proteins.
Topics: Alanine; Kinetics; Models, Molecular; Molecular Conformation; Proline; Protein Conformation; Protein Folding; Proteins; Thermodynamics | 2006 |
Amino acid catabolic pathways of lactic acid bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Aromatic; Amino Acids, Branched-Chain; Asparagine; Aspartate Ammonia-Lyase; Aspartic Acid; Biodegradation, Environmental; Fermentation; Food Microbiology; Glutamate Decarboxylase; Glutamic Acid; Glutamine; Histidine; Lactic Acid; Lactobacillus; Proline | 2006 |
The role of the Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma in diabetes risk.
Topics: Alanine; Alleles; Amino Acid Substitution; Diabetes Mellitus, Type 2; Environment; Gene Frequency; Genotype; Humans; Polymorphism, Genetic; PPAR gamma; Proline; Risk Factors | 2007 |
The varitint-waddler mouse phenotypes and the TRPML3 ion channel mutation: cause and consequence.
Topics: Alanine; Animals; Calcium; Genetic Predisposition to Disease; Genotype; Hair Color; Hearing; Hearing Disorders; Isoleucine; Membrane Potentials; Mice; Mice, Mutant Strains; Models, Molecular; Mutation; Phenotype; Proline; Protein Conformation; Protein Structure, Tertiary; Skin Pigmentation; Threonine; Transient Receptor Potential Channels; TRPM Cation Channels | 2008 |
Population description and its role in the interpretation of genetic association.
Topics: Alanine; Diabetes Mellitus, Type 2; Gene Frequency; Genetic Predisposition to Disease; Humans; Patient Selection; Polymorphism, Single Nucleotide; PPAR gamma; Proline; Racial Groups; Reproducibility of Results; Validation Studies as Topic; White People | 2010 |
Peroxisome proliferator-activated receptor γ polymorphism Pro12Ala Is associated with nephropathy in type 2 diabetes: evidence from meta-analysis of 18 studies.
Topics: Alanine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Genetic Predisposition to Disease; Genotype; Humans; Insulin Resistance; Kidney Failure, Chronic; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; PPAR gamma; Proline | 2012 |
Polymorphisms of ERBB2 and breast cancer risk: a meta-analysis of 26 studies involving 35,088 subjects.
Topics: Adult; Aged; Alanine; Alleles; Asian People; Black People; Breast Neoplasms; Case-Control Studies; Female; Genetic Predisposition to Disease; Genotype; Humans; Isoleucine; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Proline; Receptor, ErbB-2; Risk Factors; Valine; White People | 2013 |
Effects of Pro12Ala polymorphism in peroxisome proliferator-activated receptor-γ2 gene on metabolic syndrome risk: a meta-analysis.
Topics: Alanine; Case-Control Studies; Genetic Predisposition to Disease; Humans; Metabolic Syndrome; Polymorphism, Genetic; PPAR gamma; Proline | 2014 |
Meta-analysis of associations between the peroxisome proliferator-activated receptor-γ Pro12Ala polymorphism and susceptibility to nonalcoholic fatty liver disease, rheumatoid arthritis, and psoriatic arthritis.
Topics: Alanine; Arthritis, Psoriatic; Arthritis, Rheumatoid; Genetic Predisposition to Disease; Humans; Non-alcoholic Fatty Liver Disease; Polymorphism, Genetic; PPAR gamma; Proline | 2014 |
PASylation as a Powerful Technology for Improving the Pharmacokinetic Properties of Biopharmaceuticals.
Topics: Alanine; Animals; Biological Products; Biopharmaceutics; Humans; Polyethylene Glycols; Proline; Radiopharmaceuticals; Serine; Treatment Outcome | 2018 |
CCT and CCT-Like Modular Protein Interaction Domains in WNK Signaling.
Topics: Alanine; Proline; Protein Interaction Domains and Motifs; Protein Serine-Threonine Kinases; Signal Transduction | 2022 |
An update regarding the role of WNK kinases in cancer.
Topics: Alanine; Animals; Bicarbonates; Mammals; Neoplasms; Neovascularization, Pathologic; Proline; Serine; Sodium Chloride Symporters; Threonine | 2022 |
12 trial(s) available for alanine and proline
Article | Year |
---|---|
Milk protein quantity and quality in low-birth-weight infants: II. Effects on selected aliphatic amino acids in plasma and urine.
Topics: Alanine; Amino Acids; Amino Acids, Essential; Aminobutyrates; Aspartic Acid; Caseins; Citrulline; Glutamates; Glutamine; Humans; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Low Birth Weight; Infant, Newborn; Milk Proteins; Proline; Threonine | 1977 |
[The significance of nonessential amino acids for the human nitrogen metabolism during parenteral feeding].
Topics: Adult; Aged; Alanine; Amino Acids; Citrulline; Cystine; Diet; Female; Glycine; Humans; Male; Middle Aged; Nitrogen; Parenteral Nutrition; Proline; Serine; Taurine; Tyrosine | 1968 |
Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study.
Topics: Alanine; Amino Acid Substitution; Blood Glucose; Body Constitution; Body Mass Index; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Finland; Genotype; Glucose Intolerance; Humans; Incidence; Insulin; Male; Middle Aged; Mutation, Missense; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Regression Analysis; Transcription Factors | 2002 |
Analysis of the relationship between the Pro12Ala variant in the PPAR-gamma2 gene and the response rate to therapy with pioglitazone in patients with type 2 diabetes.
Topics: Aged; Alanine; Blood Glucose; Diabetes Mellitus, Type 2; Female; Genotype; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Middle Aged; Pioglitazone; Proline; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Treatment Outcome | 2003 |
Changes in insulin sensitivity in response to troglitazone do not differ between subjects with and without the common, functional Pro12Ala peroxisome proliferator-activated receptor-gamma2 gene variant: results from the Troglitazone in Prevention of Diabe
Topics: Alanine; Amino Acid Substitution; Blood Glucose; Chromans; Diabetes Mellitus, Type 2; DNA Primers; Female; Genetic Variation; Hispanic or Latino; Humans; Hypoglycemic Agents; Insulin; Polymerase Chain Reaction; PPAR gamma; Proline; Thiazolidinediones; Troglitazone | 2004 |
Endurance exercise training in orthostatic intolerance: a randomized, controlled trial.
Topics: Adult; Alanine; Autonomic Nervous System; Cardiography, Impedance; DNA; Exercise Test; Hemodynamics; Humans; Hypotension, Orthostatic; Jogging; Mutation; Norepinephrine Plasma Membrane Transport Proteins; Physical Education and Training; Physical Endurance; Proline; Symporters; Treatment Outcome | 2005 |
The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gene and change in obesity-related traits in the Diabetes Prevention Program.
Topics: Adult; Alanine; Amino Acid Substitution; Body Composition; Chromans; Diabetes Mellitus, Type 2; Dietary Fats; Eating; Female; Gene Frequency; Genotype; Humans; Hypoglycemic Agents; Life Style; Male; Metformin; Middle Aged; Obesity; Placebos; PPAR gamma; Proline; Thiazolidinediones; Troglitazone | 2007 |
Impact of the PPAR-gamma2 Pro12Ala polymorphism and ACE inhibitor therapy on new-onset microalbuminuria in type 2 diabetes: evidence from BENEDICT.
Topics: Adult; Aged; Alanine; Albuminuria; Alleles; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diabetes Complications; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Genetic Predisposition to Disease; Genotype; Homozygote; Humans; Hypertension; Incidence; Italy; Kaplan-Meier Estimate; Male; Middle Aged; Polymorphism, Single Nucleotide; PPAR gamma; Proline; Prospective Studies; Research Design; Risk Factors | 2009 |
PPARγ2 gene Pro12Ala and PPARα gene Leu162Val single nucleotide polymorphisms interact with dietary intake of fat in determination of plasma lipid concentrations.
Topics: Adult; Aged; Alanine; Amino Acid Substitution; Dietary Fats; Eating; Female; Gene-Environment Interaction; Genetic Association Studies; Humans; Leucine; Lipids; Male; Middle Aged; Mutation, Missense; Osmolar Concentration; Polymorphism, Single Nucleotide; PPAR alpha; PPAR gamma; Proline; Valine | 2011 |
FTO T/A and peroxisome proliferator-activated receptor-γ Pro12Ala polymorphisms but not ApoA1 -75 are associated with better response to lifestyle intervention in Brazilians at high cardiometabolic risk.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Amino Acid Substitution; Apolipoprotein A-I; Brazil; Cardiovascular Diseases; Female; Genetic Association Studies; Humans; Male; Metabolic Diseases; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; PPAR gamma; Proline; Promoter Regions, Genetic; Proteins; Risk Factors; Risk Reduction Behavior; Young Adult | 2013 |
Docosahexaenoic Acid-Rich Fish Oil Supplementation Improves Body Composition without Influence of the PPARγ Pro12Ala Polymorphism in Patients with Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Topics: Aged; Alanine; Amino Acid Substitution; Body Composition; Diabetes Mellitus, Type 2; Dietary Supplements; Docosahexaenoic Acids; Double-Blind Method; Fish Oils; Humans; Middle Aged; Placebos; Polymorphism, Genetic; PPAR gamma; Proline | 2015 |
An updated practical guideline on use of molnupiravir and comparison with agents having emergency use authorization for treatment of COVID-19.
Topics: Adenosine Monophosphate; Aged; Alanine; Animals; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; COVID-19 Vaccines; Cytidine; Double-Blind Method; Drug Approval; Drug Combinations; Female; Hospitalization; Humans; Hydroxylamines; Lactams; Leucine; Male; Middle Aged; Nitriles; Proline; Ritonavir; SARS-CoV-2; Severity of Illness Index; Treatment Outcome | 2022 |
1185 other study(ies) available for alanine and proline
Article | Year |
---|---|
Beta-proline analogues as agonists at the strychnine-sensitive glycine receptor.
Topics: Animals; beta-Alanine; Binding, Competitive; Glycine; In Vitro Techniques; Membrane Potentials; Mice; Proline; Rats; Receptors, GABA-A; Receptors, Glycine; Receptors, Neurotransmitter; Spinal Cord; Strychnine | 1992 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
Topics: Amino Acid Transport Systems; Caco-2 Cells; Endocytosis; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters | 2011 |
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2022 |
Effects of Na+ depletion, theophylline and 2,4-dinitrophenol on neutral amino acid influx and cyclic adenosine 3':5'-monophosphate levels in chicken small intestine.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Chickens; Cyclic AMP; Dinitrophenols; Glycine; Intestinal Mucosa; Intestine, Small; Kinetics; Leucine; Male; Proline; Sodium; Theophylline | 1976 |
Incorporation of proline into prodigiosin by a Put mutant of Serratia marcesens.
Topics: Alanine; Bacterial Proteins; Cell-Free System; Hydrogen-Ion Concentration; Kinetics; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Prodigiosin; Proline; Serratia marcescens; Temperature | 1976 |
Mapping of the locus involved in the catabolic oxidation of D-amino acids in Pseudomonas aeruginosa PAO.
Topics: Alanine; Chromosome Mapping; Conjugation, Genetic; D-Amino-Acid Oxidase; Genes; Mutation; Proline; Pseudomonas aeruginosa; Transduction, Genetic; Valine | 1978 |
The fluorescence of fluorescamine-amino acids.
Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry, Physical; Fluorescamine; Hydrogen-Ion Concentration; Kinetics; Leucine; Proline; Spectrometry, Fluorescence; Spiro Compounds; Tryptophan | 1978 |
Metabolic changes in Crithidia fasciculata accompanying physiological adaptation to growth in the presence of carbonyl cyanide m-chlorophenylhydrazone.
Topics: Adaptation, Physiological; Adenine Nucleotides; Alanine; Animals; Biological Transport; Carbon Dioxide; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Crithidia; Energy Metabolism; Hydrogen-Ion Concentration; Leucine; Nitriles; Oxygen Consumption; Proline; Tyrosine | 1979 |
Changes in the cellular content of the pool constituents of Monosporium olivaceum -- a steroid hydroxylating mould.
Topics: Alanine; Amino Acids; Arginine; Cortodoxone; Glucose; Glutamates; Lysine; Mannitol; Proline; Pseudallescheria; Steroid Hydroxylases | 1976 |
Development of a selective medium for the isolation of Clostridium sporogenes and related organisms.
Topics: Agar; Alanine; Amino Acids; Clostridium; Clostridium botulinum; Culture Media; Enterococcus faecalis; Proline; Soil Microbiology; Species Specificity; Streptococcus | 1979 |
Catabolic path of arginine and NAD regeneration in the parasite Fasciola hepatica.
Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Radioisotopes; Carboxylic Acids; Cytosol; Dogs; Fasciola hepatica; Glutamates; Ketoglutaric Acids; Mitochondria; NAD; Ornithine-Oxo-Acid Transaminase; Oxidoreductases Acting on CH-NH Group Donors; Proline; Pyrroles; Pyruvates; Urea | 1975 |
The relation between sporulation and the induction of antibiotic synthesis and of amino acid uptake in Bacillus brevis.
Topics: Alanine; Amino Acids; Bacillus; Bacterial Proteins; Carbon Radioisotopes; Cell Wall; Microscopy, Electron; Molecular Weight; Ornithine; Pantothenic Acid; Proline; Protein Binding; Rifampin; Sonication; Spores, Bacterial; Tritium; Tyrocidine; Tyrothricin | 1975 |
Lactic acidosis in three sibs due to defects in both pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase complexes.
Topics: Acidosis; Alanine; Carbohydrate Metabolism, Inborn Errors; Electron Transport Complex IV; Female; Glutamates; Humans; Infant; Infant, Newborn; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Ketone Oxidoreductases; Lactates; Male; Proline; Pyruvate Decarboxylase; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvates | 1976 |
Isolation and characterization of hydrophobic proteins (H proteins) in the membrane fraction of Bacillus subtilis. Involvement in membrane biosynthesis and the formation of biochemically active membrane vesicles by combining H proteins with lipid.
Topics: Alanine; Apoproteins; Bacillus subtilis; Bacterial Proteins; Biological Transport, Active; Cytochromes; Electron Transport Complex IV; Lipid Metabolism; Membrane Proteins; NADH, NADPH Oxidoreductases; Proline; Succinate Cytochrome c Oxidoreductase; Succinate Dehydrogenase | 1976 |
Induction of specific amino acid binding proteins preceding onset of tyrocidine synthesis in Bacillus brevis.
Topics: Alanine; Bacillus; Carrier Proteins; Molecular Weight; Ornithine; Pantothenic Acid; Proline; Rifampin; Tyrocidine; Tyrothricin; Viral Proteins | 1976 |
Chemical analysis of an angiofibroma from a patient with tuberous sclerosis.
Topics: Adult; Alanine; Collagen; Dermatan Sulfate; Facial Neoplasms; Galactosidases; Glucuronidase; Glycine; Glycosaminoglycans; Hexosaminidases; Histiocytoma, Benign Fibrous; Humans; Hyaluronic Acid; Hydroxyproline; Male; Proline; Syndrome; Tuberous Sclerosis; Water | 1977 |
Incorporation of the hydrogen atoms of ethanol into amino acids in rat liver in vivo.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chemical Phenomena; Chemistry; Deuterium; Ethanol; Female; Glutamates; Hydrogen; Liver; NAD; Proline; Rats | 1979 |
Relation between reduced nicotinamide adenine dinucleotide oxidation and amino acid transport in membrane vesicles from Bacillus subtilis.
Topics: Alanine; Amino Acids; Antimycin A; Bacillus subtilis; Biological Transport, Active; Carbon Radioisotopes; Cell Membrane; Cyanides; Glutamates; Mutation; NAD; NADH, NADPH Oxidoreductases; Nitrates; Oxidation-Reduction; Oxygen Consumption; Proline; Quinolines; Rotenone; Stereoisomerism; Vitamin K | 1975 |
Prosthecae of Asticcacaulis biprosthecum: system for the study of membrane transport.
Topics: Adenosine Triphosphate; Alanine; Ascorbic Acid; Aspartic Acid; Bacteria; Biological Transport, Active; Carbon Radioisotopes; Cell Membrane; Glucose; Glutamates; Hydrogen-Ion Concentration; Methylphenazonium Methosulfate; Oxygen Consumption; Proline; Subcellular Fractions; Temperature; Tetramethylphenylenediamine; Uncoupling Agents | 1975 |
Biosynthesis of prodigiosin by non-proliferating wild-type Serratia marcescens and mutants deficient in catabolism of alanine, histidine, and proline.
Topics: Alanine; Amino Acid Oxidoreductases; Bacterial Proteins; Histidine; Histidine Ammonia-Lyase; Mutation; Oxygen Consumption; Prodigiosin; Proline; Serratia marcescens | 1977 |
Alteration of free serum amino acids in voles infected with Trypanosoma brucei gambiense.
Topics: Alanine; Amino Acids; Animals; Arvicolinae; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Male; Proline; Serine; Threonine; Trypanosomiasis, African; Tryptophan; Tyrosine; Valine | 1977 |
Amino acid uptake and protein synthesis in germinating spores of Saccharomyces cerevisiae.
Topics: Alanine; Amino Acids; Cycloheximide; Fungal Proteins; Lysine; Proline; Saccharomyces cerevisiae; Spores, Fungal | 1977 |
Radiolabeling of and macromolecular syntheses in Neisseria gonorrhoeae types 1 and 4.
Topics: Adenine; Alanine; Autoradiography; Bacterial Proteins; Carbon Radioisotopes; Glucose; Histidine; Neisseria gonorrhoeae; Proline; RNA, Bacterial; Tritium; Uridine | 1977 |
The characterisation of inducible dehydrogenases specific for the oxidation of D-alanine, allohydroxy-D-proline, choline and sarcosine as peripheral membrane proteins in Pseudomonas aeruginosa.
Topics: Alanine; Amino Acid Oxidoreductases; Cell Membrane; Cell-Free System; Chelating Agents; Choline; Enzyme Induction; Osmolar Concentration; Oxidation-Reduction; Oxidoreductases; Proline; Pseudomonas aeruginosa; Sarcosine; Solubility; Stereoisomerism; Surface-Active Agents | 1977 |
Inhibition by glycine of the catabolic reduction of proline in Clostridium sticklandii: evidence on the regulation of amino acid reduction.
Topics: Alanine; Cell-Free System; Clostridium; Dithiothreitol; Glycine; Oxidation-Reduction; Proline; Proline Oxidase; Stereoisomerism | 1979 |
Does an excess in liver proline increase the accumulation of collagen induced by carbon tetrachloride?
Topics: Alanine; Animals; Carbon Tetrachloride Poisoning; Collagen; Hydroxyproline; Liver; Male; Proline; Rats | 1979 |
An incipient 3(10) helix in Piv-Pro-Pro-Ala-NHMe as a model for peptide folding.
Topics: Alanine; Amino Acid Sequence; Hydrogen Bonding; Models, Structural; Oligopeptides; Proline; Protein Conformation; Spectrophotometry, Infrared; Structure-Activity Relationship | 1979 |
Interaction of DNA with poly(L-Lys-L-Ala-Gly) and poly(L-Lys-L-Ala-L-Pro). Circular dichroism and thermal denaturation studies.
Topics: Alanine; Animals; Cattle; DNA; Glycine; Guanidines; Lysine; Nucleic Acid Conformation; Nucleic Acid Denaturation; Osmolar Concentration; Peptides; Proline; Protein Conformation; Protein Denaturation; Sodium Chloride; Spectrophotometry, Ultraviolet; Temperature; Thymus Gland | 1977 |
Diurnal variations in plasma concentrations of tryptophan, tryosine, and other neutral amino acids: effect of dietary protein intake.
Topics: Adult; Alanine; Amino Acids; Circadian Rhythm; Dietary Proteins; Glycine; Humans; Isoleucine; Leucine; Male; Middle Aged; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1979 |
Serum-mediated regulation of amino acid transport in cultured chick embryo fibroblasts.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport, Active; Blood; Cells, Cultured; Culture Media; DNA; Glycine; Kinetics; Proline; Serine | 1977 |
Thin layer chromatographic analyses of amino acids in Echinostoma revolutum (Trematoda) adults.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Chromatography, Thin Layer; Echinostoma; Isoleucine; Leucine; Methionine; Proline; Serine; Tyrosine; Valine | 1977 |
The effect of birth asphyxia on plasma free amino acids in preterm newborn infants.
Topics: Alanine; Amino Acids; Asphyxia Neonatorum; Blood Glucose; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Lactates; Lysine; Male; Proline; Valine | 1977 |
Adaptive regulation of amino acid transport in cultured avian fibroblasts. Influence of the amino acid composition of the culture media.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport; Cells, Cultured; Culture Media; Cycloheximide; Leucine; Lysine; Proline | 1978 |
On the maleic acid induced Fanconi syndrome: effects on transport by isolated rat kidney brushborder membrane vesicles.
Topics: Alanine; Animals; Cell Membrane; Fanconi Syndrome; Fumarates; Kidney; Lysine; Male; Maleates; Methylglucosides; Microvilli; Proline; Rats | 1978 |
[Enzymatic clevage of the peptide bonds formed by amino acid D-isomers].
Topics: Alanine; Amino Acids; Animals; Cattle; Dipeptidases; Enzyme Activation; Hydrolysis; Isomerism; Molecular Weight; Peptides; Pituitary Gland, Anterior; Proline; Protein Binding | 1978 |
Inhibition of the high-affinity, net uptake of GABA into cultured astrocytes by beta-proline, nipecotic acid and other compounds.
Topics: Alanine; Animals; Astrocytes; Brain; Cells, Cultured; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Nipecotic Acids; Proline | 1978 |
Hemoglobin A1C separation by isoelectric focusing.
Topics: Alanine; Aminocaproic Acid; Diabetes Mellitus, Type 1; Glycine; Hemoglobin A; Histidine; Humans; Isoelectric Focusing; Proline; Threonine; Valerates | 1978 |
Role of L-proline in the biosynthesis of prodigiosin.
Topics: Alanine; Bacterial Proteins; Methylnitronitrosoguanidine; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Prodigiosin; Proline; Serratia marcescens; Stereoisomerism; Temperature | 1976 |
On the mode of action of hydroxyproline in Drosophila development.
Topics: Acetylglucosamine; Alanine; Animals; Drosophila melanogaster; Glucosamine; Glutamates; Glutamine; Glutathione; Hydroxyproline; Mutation; Phenotype; Proline | 1975 |
[Amino acid pattern in endemic (Balkan-)nephropathy (author's transl)].
Topics: Adolescent; Adult; Alanine; Amino Acids; Bulgaria; Child; Citrulline; Cystine; Disease Reservoirs; Female; Glycine; Humans; Isoleucine; Leucine; Male; Methionine; Nephritis, Interstitial; Ornithine; Phenylalanine; Proline; Romania; Serine; Yugoslavia | 1976 |
Specific protein synthesis in cellular differentiation. III. The eggshell proteins of Drosophila melanogaster and their program of synthesis.
Topics: Alanine; Amino Acids; Animals; Chorion; Drosophila melanogaster; Egg Proteins; Egg Shell; Female; Oogenesis; Organ Culture Techniques; Proline; Vitelline Membrane | 1976 |
The variability of human lambda-chain constant regions and some relationships to V-regions sequences.
Topics: Alanine; Amino Acid Sequence; Chromatography, Gel; Chromatography, Ion Exchange; Cystine; Electrophoresis, Paper; Glutamates; Glycine; Humans; Immunoglobulin lambda-Chains; Immunoglobulin Light Chains; Isoleucine; Leucine; Peptides; Proline; Serine; Thiazoles; Threonine; Valine | 1976 |
Chiroptical properties of S-proline conformational isomers.
Topics: Alanine; Isomerism; Mathematics; Molecular Conformation; Optical Rotation; Proline | 1977 |
On the derivatives for the ultramicrodetermination of amino acids by mass fragmentography.
Topics: Alanine; Amino Acids; Gas Chromatography-Mass Spectrometry; Glutamates; Indicators and Reagents; Leucine; Microchemistry; Proline; Valine | 1977 |
Metabolism in the hypothermically perfused dog kidney. Utilization and production of amino acids.
Topics: Alanine; Amino Acids; Ammonia; Animals; Dogs; Fatty Acids; Gluconeogenesis; Glucose; Glutamates; Glutamine; Glycine; Hypothermia, Induced; Kidney; Lactates; Nitrogen; Organ Preservation; Perfusion; Proline; Urea | 1977 |
Selenium requirement for the growth of Clostridium sporogenes with glycine as the oxidant in stickland reaction systems.
Topics: Alanine; Amino Acid Oxidoreductases; Clostridium; Fermentation; Glycine; Proline; Selenium | 1977 |
Carbohydrate effects of amino acid transport by Trypanosoma equiperdum.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Carbohydrate Metabolism; Glucose; Glutamates; Iodoacetates; Lysine; Methionine; Phenylalanine; Proline; Trypanosoma | 1977 |
Muscle amino acid arylpeptidases and their serum changes with exercise.
Topics: Adolescent; Adult; Alanine; Aminopeptidases; Glycine; Humans; Leucine; Male; Muscles; Phenylalanine; Physical Exertion; Proline; Running; Skiing; Tyrosine | 1977 |
Vibrational spectra of glycine, alanine and proline oligomers in relation to their polymeric forms.
Topics: Alanine; Glycine; Molecular Conformation; Peptides; Proline; Spectrophotometry, Infrared | 1976 |
Polypeptide models of collagen: synthesis of (Pro-Pro-Ala)n and (Pro-Pro-Val)n.
Topics: Alanine; Circular Dichroism; Collagen; Models, Chemical; Molecular Weight; Optical Rotatory Dispersion; Peptides; Proline; Valine | 1976 |
The X-Pro peptide bond as an nmr probe for conformational studies of flexible linear peptides.
Topics: Alanine; Binding Sites; Glycine; Leucine; Magnetic Resonance Spectroscopy; Molecular Conformation; Peptides; Phenylalanine; Proline; Stereoisomerism | 1976 |
Nmr studies of the molecular conformations in the linear oligopeptides H-(L-Ala)n-L-Pro-OH.
Topics: Alanine; Binding Sites; Hydrogen; Magnetic Resonance Spectroscopy; Molecular Conformation; Oligopeptides; Proline; Stereoisomerism | 1976 |
Self complementarity in messenger RNA of collagen. I. Possible hairpin structures in regions coding for oligopeptides of glycine, proline (hydroxyproline) and alanine.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Collagen; Computers; Genetic Code; Glycine; Hydroxyproline; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligopeptides; Proline; Protein Biosynthesis; Protein Conformation; RNA, Messenger; Thermodynamics | 1976 |
An explanation for the rare occurrence of cis peptide units in proteins and polypeptides.
Topics: Alanine; Amino Acid Sequence; Calorimetry; Mathematics; Models, Molecular; Peptides; Proline; Protein Conformation; Proteins | 1976 |
The metabolic effects of glucagon infusion in normoglycaemic and hypoglycaemic small-for-gestational-age infants. II. Changes in plasma amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Blood Glucose; Citrulline; Glucagon; Gluconeogenesis; Glycine; Humans; Hypoglycemia; Infant, Low Birth Weight; Infant, Newborn; Infant, Small for Gestational Age; Infusions, Parenteral; Isoleucine; Leucine; Liver; Proline; Valine | 1976 |
Amino acid composition, distribution and origin of "tuft" protein in human and bovine dental enamel.
Topics: Alanine; Amelogenesis; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Dental Enamel; Dental Enamel Proteins; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Free amino acids and amines in human dental plaque.
Topics: Alanine; Amines; Amino Acids; Aminobutyrates; Aspartic Acid; Cadaverine; Chemical Fractionation; Chromatography, Thin Layer; Dansyl Compounds; Dental Plaque; Fluorescence; Fluorometry; Glutamates; Glycine; Histamine; Humans; Ion Exchange; Lysine; Proline; Putrescine; Serine; Threonine; Valine | 1975 |
Amino acid transport in peripheral nerve: energy and sodium dependence.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Choline; Dinitrophenols; Energy Transfer; Glutamates; Glycine; Lithium; Lysine; Phenylalanine; Potassium; Proline; Rana catesbeiana; Sciatic Nerve; Sodium; Temperature; Tromethamine; Valine | 1975 |
Coupling of alanine racemase and D-alanine dehydrogenase to active transport of amino acids in Escherichia coli B membrane vesicles.
Topics: Acetates; Alanine; Amino Acid Isomerases; Amino Acid Oxidoreductases; Amino Acids; Biological Transport, Active; Cell Membrane; Dinitrophenols; Dithiothreitol; Escherichia coli; Hydroxylamines; Kinetics; Proline; Pyruvates; Stereoisomerism; Time Factors | 1975 |
Transport properties of merodiploids covering the dagA locus in Escherichia coli K-12.
Topics: Alanine; Biological Transport, Active; Cell Membrane; Diploidy; Escherichia coli; Genes; Glycerol; Glycine; Kinetics; Leucine; Mutation; Proline; Serine; Stereoisomerism | 1975 |
Effect of ethanol on the metabolsim of alanine glutamic acid, and proline in rat liver.
Topics: Alanine; Animals; Ethanol; Glutamates; In Vitro Techniques; Ketoglutaric Acids; Lactates; Liver; Male; Proline; Pyruvates; Rats | 1975 |
Asparagine metabolism in the bovine lens: a comparison with the metabolism of aspartic acid.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Biological Transport; Cattle; Eye Proteins; Glutamates; Glutamine; Glutathione; Lactates; Lens, Crystalline; Proline | 1975 |
Quality control during peptide synthesis. I. Quantitative monitoring of resin bound amines.
Topics: Alanine; Evaluation Studies as Topic; Glycine; Methods; Peptides; Proline; Resins, Plant; Sarcosine; Spectrometry, Fluorescence; Temperature; Time Factors | 1975 |
The requirements of the brain for some amino acids.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Brain; Carbon Radioisotopes; Glycine; Kinetics; Proline; Rats; Serine; Sulfur Radioisotopes; Time Factors | 1975 |
Hemoglobin Atlanta or alpha 2 beta 2 75 Leu-Pro (E19): an unstable variant found in several members of a Caucasian family.
Topics: Alanine; Amino Acids; Female; Georgia; Heinz Bodies; Hemoglobins, Abnormal; Humans; Leucine; Peptide Fragments; Proline; Protein Conformation; White People | 1975 |
Oxytocin analogs with substitutions in postions 3 and 4.
Topics: Alanine; Animals; Chickens; Leucine; Oxytocin; Proline; Rats | 1975 |
Membrane transport in Schistosoma mansoni: transport of amino acids by adult males.
Topics: Alanine; Amino Acids; Animals; Arginine; Biological Transport; Chromatography; Cysteine; Female; Glutamates; Glycine; Kinetics; Male; Methionine; Mice; Proline; Schistosoma mansoni; Tryptophan | 1975 |
Hyperaminoacidemia due to the accumulation of gluconeogenic amino acid precursors in hypoglycemic small-for-gestational age infants.
Topics: Alanine; Amino Acids; Birth Weight; Female; Gestational Age; Gluconeogenesis; Glycine; Humans; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Nutrition Disorders; Pregnancy; Proline; Valine | 1975 |
Free amino acids in plasma and tissue of rats born to underfed dams.
Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Arginine; Body Weight; Female; Glutamates; Glycine; Lactation; Liver; Male; Maternal-Fetal Exchange; Muscles; Nutrition Disorders; Pregnancy; Pregnancy, Animal; Proline; Rats; Valine | 1975 |
Amino acid reabsorption in the rat nephron. Free flow micropuncture study.
Topics: Absorption; Alanine; Amino Acids; Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Glutamates; Glycine; Isoleucine; Kidney; Kidney Tubules, Proximal; Leucine; Lysine; Male; Nephrons; Phenylalanine; Proline; Rats; Taurine; Tyrosine | 1975 |
[Dipeptidase activity in the small intestine of patients with chronic nonspecific enteritis].
Topics: Adult; Alanine; Chronic Disease; Dipeptidases; Dipeptides; Enteritis; Female; Glutamates; Glycine; Humans; Intestine, Small; Isoleucine; Leucine; Male; Middle Aged; Proline; Valine | 1975 |
The nature and control of the tricarboxylate cycle in beetle flight muscle.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Alanine Transaminase; Ammonia; Animals; Citric Acid Cycle; Coleoptera; Female; Glutamate Dehydrogenase; Kinetics; Malate Dehydrogenase; Male; Mitochondria, Muscle; Muscles; Oxygen Consumption; Proline; Pyruvates | 1975 |
Polypeptide models of collagen. Synthesis of (Pro-Pro-beta-Ala)n.
Topics: Alanine; Amino Acid Sequence; Chromatography, Gel; Circular Dichroism; Collagen; Molecular Weight; Optical Rotatory Dispersion; Peptides; Proline; Protein Conformation | 1975 |
Compartmentalization of amino acids in surfactant aggregates. Partitioning between water and aqueous micellar sodium deodecanoate and between hexane and dodecylammonium propionate trapped water in hexane.
Topics: Alanine; Alkanes; Amino Acids; Arginine; Aspartic Acid; Colloids; Glutamates; Glycine; Isoleucine; Laurates; Leucine; Lysine; Micelles; Phenylalanine; Proline; Serine; Solubility; Threonine; Valine | 1975 |
[Free amino acids in the amniotic fluid and in maternal blood in advanced pregnancy].
Topics: Alanine; Amino Acids; Amniotic Fluid; Cysteine; Female; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Pregnancy Trimester, Third; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Nutrition of Vitreoscilla stercoraria.
Topics: Alanine; Amino Acids; Aspartic Acid; Cysteine; Glutamates; Glutamine; Proline; Serine; Thiotrichaceae | 1975 |
Studies on trypsin inhibitors. Part I. Synthesis of protected peptides related to sequence 1-10 of porcine pancreatic secretory trypsin inhibitor II (Kazal).
Topics: Alanine; Animals; Arginine; Cysteine; Glutamine; Peptides; Proline; Serine; Swine; Threonine; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Valine | 1976 |
Hb Altdorf alpha2beta2 135 (H13) Ala leads to Pro: a new electrophoretically silent unstable haemoglobin variant from Switzerland.
Topics: Alanine; Amino Acids; Binding Sites; Drug Stability; Genetic Variation; Hemoglobins, Abnormal; Humans; Kinetics; Oxygen; Proline; Protein Binding; Switzerland | 1976 |
Attempted synthesis of 2-methylalanyl-L-prolyl-L-tryptophan. An unexpected result.
Topics: Alanine; Amino Acid Sequence; Oligopeptides; Proline; Tryptophan | 1976 |
Biosynthesis of amino acids from 3-(14C)-pyruvate in the fiddler crab Uca pugilator.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brachyura; Glutamates; Glutamine; Proline; Protein Biosynthesis; Pyruvates; Serine; Time Factors | 1976 |
Glycine transport in normal and non-ketotic hyperglycinemic human diploid fibroblasts.
Topics: Alanine; Biological Transport, Active; Carrier Proteins; Cell Line; Chloramphenicol; Glycine; Kinetics; Methionine; Ouabain; Potassium; Proline; Sodium; Sulfhydryl Reagents; Temperature | 1976 |
Characterization of the stabilizing effect of point mutations of pyruvate oxidase from Lactobacillus plantarum: protection of the native state by modulating coenzyme binding and subunit interaction.
Topics: Alanine; Amino Acid Sequence; Asparagine; Enzyme Stability; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Kinetics; Lactobacillus; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Proline; Protein Denaturation; Pyruvate Oxidase; Recombinant Proteins; Serine; Spectrophotometry, Ultraviolet; Thiamine Pyrophosphate; Urea; Valine | 1992 |
Amino acid transport systems in the human hepatoma cell line Hep G2.
Topics: Alanine; Amino Acids; Biological Transport; Carcinoma, Hepatocellular; Humans; Kinetics; Lithium; Liver Neoplasms; Proline; Serine; Sodium; Tumor Cells, Cultured | 1992 |
The presence of free D-alanine, D-proline and D-serine in mice.
Topics: Alanine; Amino Acids; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; D-Amino-Acid Oxidase; Kidney; Mice; Mice, Mutant Strains; Proline; Serine; Stereoisomerism | 1992 |
[The question of amino acid isomerization in the microwave field. Results of a model study with standard solutions].
Topics: Alanine; Amino Acids; Glutamates; Glutamic Acid; Isomerism; Microwaves; Proline | 1992 |
The presence of free D-serine, D-alanine and D-proline in human plasma.
Topics: Adult; Aged; Alanine; Amino Acids; Chromatography, High Pressure Liquid; Creatinine; Female; Humans; Male; Middle Aged; Proline; Reference Values; Serine; Stereoisomerism | 1992 |
L-threonine transport in pig jejunal brush border membrane vesicles. Functional characterization of the unique system B in the intestinal epithelium.
Topics: Alanine; Animals; Biological Transport; In Vitro Techniques; Intestinal Absorption; Jejunum; Kinetics; Lysine; Membrane Potentials; Microvilli; Phenylalanine; Proline; Sodium; Swine; Threonine | 1992 |
Effect of sodium chloride on the intracellular solute pools of Listeria monocytogenes.
Topics: Alanine; Amino Acids; Betaine; Glycine; Intracellular Fluid; Listeria monocytogenes; Osmotic Pressure; Potassium; Proline; Sodium Chloride | 1992 |
Conformational studies on beta-bend containing a cis peptide unit.
Topics: Alanine; Amino Acid Sequence; Glycine; Isomerism; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Oligopeptides; Proline; Protein Conformation; Protein Structure, Secondary | 1992 |
Determination of D- and L-amino acids in mouse kidney by high-performance liquid chromatography.
Topics: Alanine; Amino Acids; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Kidney; Mice; Proline; Serine; Stereoisomerism | 1992 |
Origin of the mutual activation of the alpha and beta 2 subunits in the alpha 2 beta 2 complex of tryptophan synthase. Effect of alanine or glycine substitutions at proline residues in the alpha subunit.
Topics: Alanine; Calorimetry; Enzyme Activation; Escherichia coli; Genes, Bacterial; Glycine; Kinetics; Ligands; Macromolecular Substances; Mutagenesis, Site-Directed; Plasmids; Proline; Restriction Mapping; Tryptophan Synthase | 1992 |
Quantitation of the effects of an internal proline residue on individual hydrogen bond stabilities in an alpha-helix: pH-dependent amide exchange in melittin and [Ala-14]melittin.
Topics: Alanine; Amides; Amino Acid Sequence; Hydrogen Bonding; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Melitten; Methanol; Molecular Sequence Data; Proline; Protein Conformation; Thermodynamics | 1992 |
Some proline substituent effects in the tandem mass spectrum of protonated pentaalanine.
Topics: Alanine; Amino Acid Sequence; Gas Chromatography-Mass Spectrometry; Kinetics; Mass Spectrometry; Molecular Sequence Data; Proline | 1992 |
Differential helix propensity of small apolar side chains studied by molecular dynamics simulations.
Topics: Alanine; Amino Acids; Aminobutyrates; Glycine; Hydrogen Bonding; Leucine; Peptides; Proline; Protein Conformation; Structure-Activity Relationship; Thermodynamics; Valine | 1992 |
Receptor sites for amino acids in the facial taste system of the channel catfish.
Topics: Action Potentials; Adaptation, Physiological; Alanine; Animals; Arginine; Electrophysiology; Glutamates; Glutamic Acid; Histidine; Ictaluridae; Lysine; Methionine; Proline; Receptors, Amino Acid; Receptors, Cell Surface; Stereoisomerism; Taste | 1991 |
Structure/function relationships in the inhibition of thimet oligopeptidase by carboxyphenylpropyl-peptides.
Topics: Alanine; Amino Acid Sequence; Metalloendopeptidases; Molecular Sequence Data; Peptides; Proline; Structure-Activity Relationship; Thermodynamics | 1991 |
Alteration of HIV-1 infectivity and neutralization by a single amino acid replacement in the V3 loop domain.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Cell Fusion; Cell Line, Transformed; Cloning, Molecular; DNA, Viral; HIV Envelope Protein gp120; HIV-1; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Neutralization Tests; Peptide Fragments; Proline; Virus Replication | 1991 |
Determination of the enantiomeric purity of synthetic peptides by gas chromatography-mass spectrometry.
Topics: Acetates; Alanine; Amino Acid Sequence; Amino Acids; Deuterium; Esters; Fenclonine; Gas Chromatography-Mass Spectrometry; Hydrolysis; Indicators and Reagents; Isotope Labeling; Molecular Sequence Data; Peptides; Proline; Stereoisomerism | 1991 |
The conserved, buried aspartic acid in oxidized Escherichia coli thioredoxin has a pKa of 7.5. Its titration produces a related shift in global stability.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Binding Sites; Buffers; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Proline; Protein Conformation; Sulfhydryl Compounds; Thioredoxins | 1991 |
Proline in alpha-helix: stability and conformation studied by dynamics simulation.
Topics: Alanine; Computer Simulation; Mathematical Computing; Models, Molecular; Oligopeptides; Peptides; Proline; Protein Conformation | 1991 |
Antithrombin Cambridge II, 384 Ala to Ser. Further evidence of the role of the reactive centre loop in the inhibitory function of the serpins.
Topics: Aged; Alanine; Antithrombin III; Base Sequence; Binding Sites; Exons; Heparin; Humans; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Proline; Protein Conformation; Serine; Serpins; Threonine; Thrombophlebitis; United Kingdom | 1991 |
Analysis of neutral amino acid transport systems in the small intestine: a study of brush border membrane vesicles.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Culture Media; Cysteine; Guinea Pigs; Ileum; In Vitro Techniques; Leucine; Microvilli; Proline; Serine | 1991 |
Glomerulopressin production by isolated rat liver after amino acid infusion.
Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Analysis of Variance; Animals; Dinoprostone; Dose-Response Relationship, Drug; Female; Glucuronates; Infusions, Intravenous; Liver; Male; Muscle Tonus; Muscle, Smooth; Proline; Rats; Rats, Inbred Strains; Serine | 1991 |
Concentrations of amino acids in the plasma of neonatal foals with septicemia.
Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Arginine; Citrulline; Female; Glycine; Gram-Negative Bacteria; Horse Diseases; Horses; Immunoglobulin G; Isoleucine; Male; Phenylalanine; Proline; Sepsis; Threonine; Valine | 1991 |
Secondary structure and side-chain 1H and 13C resonance assignments of calmodulin in solution by heteronuclear multidimensional NMR spectroscopy.
Topics: Alanine; Amino Acid Sequence; Amino Acids, Branched-Chain; Amino Acids, Diamino; Amino Acids, Dicarboxylic; Animals; Asparagine; Binding Sites; Calcium; Calmodulin; Drosophila melanogaster; Glutamine; Glycine; Hydrogen Bonding; Leucine; Magnetic Resonance Spectroscopy; Methionine; Molecular Sequence Data; Molecular Structure; Proline; Recombinant Proteins; Serine; Solutions; Threonine | 1991 |
Interindividual and longitudinal studies of amino acid composition of pellicle collected in vivo.
Topics: Alanine; Amino Acids; Dental Deposits; Dental Pellicle; Glutamates; Glutamic Acid; Glycine; Humans; Longitudinal Studies; Proline; Saliva | 1990 |
Molecular sizes of amino acid transporters in the luminal membrane from the kidney cortex, estimated by the radiation-inactivation method.
Topics: Alanine; Amino Acid Transport Systems; Amino Acids; Animals; Benzoates; Benzoic Acid; Biological Transport; Carrier Proteins; Cell Membrane Permeability; Dose-Response Relationship, Radiation; Free Radicals; Gamma Rays; Glutamates; Glutamic Acid; Kidney Cortex; Kinetics; Leucine; Microvilli; Proline; Rats; Sodium | 1990 |
Cationic and anionic amino acid transport studies in rat red blood cells.
Topics: Alanine; Animals; Biological Transport; Dose-Response Relationship, Drug; Erythrocytes; Female; Glutamates; Glutamic Acid; Lysine; Proline; Rats; Rats, Inbred Strains; Time Factors | 1990 |
Role of conserved proline residues in stabilizing tryptophan synthase alpha subunit: analysis by mutants with alanine or glycine.
Topics: Alanine; Calorimetry; Circular Dichroism; Enzyme Stability; Glycine; Guanidine; Guanidines; Mutagenesis, Site-Directed; Proline; Protein Conformation; Protein Denaturation; Thermodynamics; Tryptophan Synthase | 1991 |
Contribution of proline-14 to the structure and actions of melittin.
Topics: Alanine; Amino Acid Sequence; Electric Conductivity; Hemolysis; Humans; Hydrogen Bonding; Lipid Bilayers; Magnetic Resonance Spectroscopy; Melitten; Proline; Protein Conformation | 1991 |
Membrane potential and amino acid transport in a mutant Chinese hamster ovary cell line.
Topics: Alanine; Amino Acids; Animals; Arginine; Biological Transport; Cell Line; Cricetinae; Cricetulus; Electric Conductivity; Female; Membrane Potentials; Ovary; Proline; Sodium | 1991 |
Proline for alanine substitutions in the C-peptide helix of ribonuclease A.
Topics: Alanine; Amino Acid Sequence; Circular Dichroism; Electronic Data Processing; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptide Fragments; Proline; Protein Conformation; Ribonuclease, Pancreatic | 1991 |
Effects of amino acid isomers on canine renal hemodynamics.
Topics: Alanine; Amino Acids; Animals; Dogs; Female; Glomerular Filtration Rate; Hemodynamics; Male; Proline; Renal Circulation; Serine; Stereoisomerism | 1990 |
Pro----Ala-35 Rhodobacter capsulatus cytochrome c2 shows dynamic not structural differences. A 1H and 15N NMR study.
Topics: Alanine; Cytochrome c Group; Cytochromes c2; Enzyme Stability; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Structure; Mutation; Proline; Protein Conformation; Rhodospirillaceae | 1990 |
An investigation of the substrate specificity of protein phosphatase 2C using synthetic peptide substrates; comparison with protein phosphatase 2A.
Topics: Alanine; Amino Acid Sequence; Angiotensin II; Animals; Arginine; Binding Sites; Molecular Sequence Data; Phosphopeptides; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Proline; Protein Phosphatase 2; Substrate Specificity; Valine | 1990 |
FrzE of Myxococcus xanthus is homologous to both CheA and CheY of Salmonella typhimurium.
Topics: Alanine; Amino Acid Sequence; Base Sequence; DNA Transposable Elements; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Molecular Sequence Data; Mutation; Myxococcales; Plasmids; Proline; Pyruvate Dehydrogenase Complex; Restriction Mapping; Salmonella typhimurium; Sequence Homology, Nucleic Acid; Signal Transduction | 1990 |
Factor IXHollywood: substitution of Pro55 by Ala in the first epidermal growth factor-like domain.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Restriction Enzymes; Epidermal Growth Factor; Exons; Factor IX; Factor IXa; Genetic Markers; Hemophilia A; Humans; Molecular Sequence Data; Mutation; Partial Thromboplastin Time; Polymerase Chain Reaction; Proline; Promoter Regions, Genetic; Protein Conformation | 1990 |
Changing the invariant proline-30 of rat and Drosophila melanogaster cytochromes c to alanine or valine destabilizes the heme crevice more than the overall conformation.
Topics: Alanine; Animals; Binding Sites; Cloning, Molecular; Cytochrome c Group; Drosophila melanogaster; Heme; Hot Temperature; Proline; Protein Conformation; Rats; Recombinant Proteins; Spectrum Analysis; Structure-Activity Relationship; Urea; Valine | 1990 |
Uptake and metabolism of dipeptides by human red blood cells.
Topics: Alanine; Biological Transport; Dipeptides; Erythrocytes; Glycine; Humans; Kinetics; Proline | 1990 |
Distinct binding sites of Ala48-hirudin1-47 and Ala48-hirudin48-65 on alpha-thrombin.
Topics: Alanine; Amino Acid Sequence; Animals; Cattle; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Hirudins; Humans; Molecular Sequence Data; Mutation; Proline; Thrombin | 1990 |
Swelling of rat hepatocytes stimulates glycogen synthesis.
Topics: Alanine; Aminoisobutyric Acids; Animals; Asparagine; Glutamine; In Vitro Techniques; Liver; Liver Glycogen; Organ Size; Osmolar Concentration; Proline; Raffinose; Rats; Sucrose | 1990 |
Conformational calculations on the Ala14-Pro27 LC1 segment of rabbit skeletal myosin.
Topics: Alanine; Amino Acid Sequence; Animals; Chemical Phenomena; Chemistry, Physical; Molecular Sequence Data; Molecular Structure; Muscles; Myosins; Proline; Protein Conformation; Rabbits; Thermodynamics | 1990 |
Substitution of a proline for alanine 183 in the hinge region of phosphoglycerate kinase: effects on catalysis, activation by sulfate, and thermal stability.
Topics: Alanine; Calorimetry, Differential Scanning; Catalysis; Enzyme Activation; Hot Temperature; Mutation; Oligonucleotides; Phosphoglycerate Kinase; Proline; Protein Conformation; Protein Denaturation; Structure-Activity Relationship; Sulfates; Yeasts | 1990 |
Inhibition of angiotensin converting enzyme by L-alanyl-4 or 5-substituted-L-prolines and their N alpha-phosphoryl-derivatives.
Topics: Alanine; Amino Acid Sequence; Angiotensin-Converting Enzyme Inhibitors; Binding Sites; Molecular Sequence Data; Organophosphorus Compounds; Proline; Structure-Activity Relationship | 1990 |
Biophysical studies of engineered mutant proteins based on calbindin D9k modified in the pseudo EF-hand.
Topics: Alanine; Animals; Binding Sites; Calbindins; Calcium; Escherichia coli; Gene Expression; Glycine; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Mutation; Proline; Protein Conformation; Protein Engineering; Recombinant Proteins; S100 Calcium Binding Protein G; Temperature | 1990 |
The sodium ion translocating oxalacetate decarboxylase of Klebsiella pneumoniae. Sequence of the biotin-containing alpha-subunit and relationship to other biotin-containing enzymes.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Biotin; Carboxy-Lyases; Electrophoresis, Polyacrylamide Gel; Ion Channels; Klebsiella pneumoniae; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Proline; Serine Endopeptidases; Sodium; Trypsin | 1988 |
Nature of the renal hemodynamic action of amino acids in dogs.
Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Anesthesia, General; Animals; Dogs; Female; Glomerular Filtration Rate; Liver; Male; Proline; Renal Circulation; Serine; Splanchnic Circulation | 1989 |
Uptake of lysine and proline via separate alpha-neutral amino acid transport pathways in Mytilus gill brush border membranes.
Topics: Alanine; Animals; Biological Transport, Active; Bivalvia; Cations, Monovalent; Gills; Harmaline; Kinetics; Lysine; Membrane Potentials; Microvilli; Proline | 1989 |
Characteristics of acidic, basic and neutral amino acid transport in the perfused rat hindlimb.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Female; Glutamates; Glycine; Hindlimb; Insulin; Kinetics; Lysine; Methylhistidines; Proline; Rats; Rats, Inbred Strains; Sarcolemma; Serine; Sodium | 1989 |
Structure-function studies on bacteriorhodopsin. VIII. Substitutions of the membrane-embedded prolines 50, 91, and 186: the effects are determined by the substituting amino acids.
Topics: Alanine; Amino Acid Sequence; Bacteriorhodopsins; Cell Membrane; Glycine; Light; Membrane Proteins; Molecular Sequence Data; Mutation; Proline; Protein Conformation; Protons; Sodium Chloride; Structure-Activity Relationship; Valine | 1989 |
Metabolism of 3H- and 14C-labeled glutamate, proline, and alanine in normal and adrenalectomized rats using different sites of tracer administration and sampling.
Topics: Adrenalectomy; Alanine; Animals; Arteries; Body Composition; Carbon Radioisotopes; Glucose; Glutamates; Glutamic Acid; Hydrocortisone; Kinetics; Lactates; Lactic Acid; Male; Proline; Rats; Rats, Inbred Strains; Tritium; Veins | 1989 |
The determination of mass of metabolites with tracers.
Topics: Alanine; Amino Acids; Animals; Arteries; Body Composition; Body Water; Carbon Radioisotopes; Chickens; Dogs; Glucose; Glutamates; Glutamic Acid; Lactates; Lactic Acid; Male; Mathematics; Proline; Rabbits; Rats; Tritium; Veins | 1989 |
Substitution of amino acids in helix F of bacteriorhodopsin: effects on the photochemical cycle.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Bacteriorhodopsins; Glutamates; Glutamic Acid; Glutamine; Glycine; Hydrogen Bonding; Kinetics; Leucine; Molecular Sequence Data; Mutation; Phenylalanine; Photochemistry; Proline; Protons; Serine; Tryptophan | 1989 |
Hb Fontainebleau [alpha 21(B2)Ala----pro], a new silent mutant hemoglobin.
Topics: Adolescent; Alanine; Amino Acid Sequence; Female; Genetic Variation; Hemoglobins, Abnormal; Humans; Male; Molecular Sequence Data; Mutation; Pedigree; Proline | 1989 |
Hb Brockton [alpha 2 beta 2138(H16)Ala----Pro] observed in a Turkish girl.
Topics: Alanine; Amino Acid Sequence; Child; Chromatography, High Pressure Liquid; Female; Hemoglobins, Abnormal; Humans; Male; Molecular Sequence Data; Peptide Fragments; Proline; Protein Denaturation; Turkey | 1989 |
The flexible region of protein L12 from bacterial ribosomes studied by proton nuclear magnetic resonance.
Topics: Acetylation; Alanine; Amino Acid Sequence; Bacterial Proteins; Escherichia coli; Glycine; Macromolecular Substances; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutation; Proline; Protein Conformation; Ribosomal Proteins; Valine | 1989 |
Excretion of amino acids by 1,2,4-triazole-3-alanine-resistant mutants of Methanococcus voltae.
Topics: Alanine; Amino Acids; Drug Resistance, Microbial; Euryarchaeota; Histidine; Methionine; Mutation; Phenylalanine; Proline; Tyrosine | 1989 |
How many Na+-dependent carriers for L-alanine and L-proline in the eel intestine? Studies with brush-border membrane vesicles.
Topics: Alanine; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Aminoisobutyric Acids; Anguilla; Animals; Carrier Proteins; Intestinal Mucosa; Kinetics; Microvilli; Muscle, Smooth; Proline; Sodium; Symporters | 1989 |
Antithrombin Cambridge, 384 Ala to Pro: a new variant identified using the polymerase chain reaction.
Topics: Adult; Alanine; Antithrombin III; Base Sequence; Chromatography; DNA; DNA-Directed DNA Polymerase; Exons; Family; Female; Gene Amplification; Humans; Mutation; Oligonucleotides; Proline; Thrombosis | 1989 |
A resonance Raman study on the structures of complexes of flavoprotein D-amino acid oxidase.
Topics: Alanine; Animals; Binding Sites; D-Amino-Acid Oxidase; Kidney; Lysine; Oxidation-Reduction; Proline; Protons; Spectrum Analysis, Raman; Swine | 1986 |
Modulation of amino acid and 2-oxo acid pools in Trichomonas vaginalis by aspartate aminotransferase inhibitors.
Topics: Alanine; Amino Acids; Amino Acids, Dicarboxylic; Aminooxyacetic Acid; Animals; Aspartate Aminotransferases; Culture Media; Glutamates; Glutamic Acid; Hydroxamic Acids; Leucine; Proline; Trichomonas vaginalis | 1986 |
13C-NMR studies on the reaction intermediates of porcine kidney D-amino acid oxidase reconstituted with 13C-enriched flavin adenine dinucleotide.
Topics: Alanine; Animals; D-Amino-Acid Oxidase; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Kidney; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Proline; Spectrophotometry; Swine | 1987 |
Porcine muscle prolyl endopeptidase: limited proteolysis of tryptic peptides from hemoglobin beta-chains at prolyl and alanyl bonds.
Topics: Alanine; Amino Acid Sequence; Animals; Endopeptidases; Hemoglobins; Macaca; Molecular Sequence Data; Molecular Weight; Muscles; Proline; Prolyl Oligopeptidases; Serine Endopeptidases; Swine; Temperature; Trypsin | 1988 |
Echinococcus granulosus: absorption of cycloleucine and alpha-aminoisobutyric acid by protoscoleces.
Topics: Absorption; Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Cycloleucine; Diffusion; Echinococcus; Hydrogen-Ion Concentration; Leucine; Methionine; Proline; Serine; Valine | 1986 |
Gamma-aminobutyric acid and the high pressure neurological syndrome.
Topics: Alanine; Aminobutyrates; Animals; Atmospheric Pressure; Central Nervous System Diseases; Electrodes, Implanted; Electroencephalography; gamma-Aminobutyric Acid; High Pressure Neurological Syndrome; Male; Myoclonus; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Tremor; Valproic Acid | 1986 |
Three uptake systems in synaptosomes for nipecotic acid and beta-alanine.
Topics: Alanine; Animals; beta-Alanine; In Vitro Techniques; Kinetics; Male; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Synaptosomes | 1986 |
Characterization of carrier-mediated transport systems for small neutral amino acids in human fibroblast lysosomes.
Topics: Alanine; Amino Acids; Biological Transport, Active; Fibroblasts; Humans; Kinetics; Lysosomes; Mathematics; Osmolar Concentration; Proline; Serine; Sodium Chloride; Threonine | 1987 |
Echinococcus granulosus (Cestoda): uptake of L-amino acids by secondary hydatid cysts.
Topics: Absorption; Alanine; Amino Acids; Animals; Biological Transport; Cycloleucine; Echinococcosis; Echinococcus; Kinetics; Mathematics; Mice; Mice, Inbred BALB C; Proline; Threonine | 1988 |
Comparisons of glucose and amino acid use in adults and microfilariae of Brugia pahangi.
Topics: Aerobiosis; Alanine; Amino Acids; Anaerobiosis; Animals; Brugia; Carbon Dioxide; Glucose; Glutamates; Glycine; Microfilariae; Proline; Proline Oxidase | 1988 |
A mutant pyruvate dehydrogenase complex of Escherichia coli deleted in the (alanine + proline)-rich region of the acetyltransferase component.
Topics: Acetyltransferases; Alanine; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Catalysis; Escherichia coli; Genes; Genes, Bacterial; Proline; Protein Conformation; Pyruvate Dehydrogenase Complex | 1987 |
Replacement of proline-76 with alanine eliminates the slowest kinetic phase in thioredoxin folding.
Topics: Alanine; Bacterial Proteins; Escherichia coli; Guanidine; Guanidines; Kinetics; Models, Molecular; Mutation; Proline; Protein Conformation; Protein Denaturation; Thioredoxins | 1987 |
[Can amino acids inhibit acid formation in Streptococcus mutans?].
Topics: Alanine; Amino Acids; Arginine; Aspartame; Glycine; Histidine; Humans; Proline; Streptococcus mutans | 1987 |
Insulin dose-dependent reductions in plasma amino acids in man.
Topics: Adult; Alanine; Amino Acids; Blood Glucose; Dose-Response Relationship, Drug; Glucose; Glycine; Humans; Insulin; Isoleucine; Male; Proline | 1986 |
Characterization of ribosomal frameshift events by protein sequence analysis.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Codon; Proline; Protein Biosynthesis; Ribosomes; RNA, Messenger; RNA, Transfer | 1986 |
Autoradiographic study of the distribution of [3H]gamma-aminobutyrate-accumulating neural elements in guinea-pig intestine: evidence for a transmitter function of gamma-aminobutyrate.
Topics: Alanine; Amino Acids; Amino Acids, Cyclic; Aminobutyrates; Animals; Autoradiography; Colon; Cyclohexanecarboxylic Acids; Female; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; Leucine; Male; Myenteric Plexus; Neurons; Nipecotic Acids; Paraffin; Proline | 1986 |
1H-NMR study of mobility and conformational constraints within the proline-rich N-terminal of the LC1 alkali light chain of skeletal myosin. Correlation with similar segments in other protein systems.
Topics: Actins; Alanine; Binding Sites; Magnetic Resonance Spectroscopy; Myosin Subfragments; Myosins; Peptide Fragments; Proline; Protein Conformation | 1986 |
Proline requirement for glucose utilization by Peptostreptococcus anaerobius ATCC 27337.
Topics: Adenosine Triphosphate; Alanine; Anaerobiosis; Biological Transport; Carbon Radioisotopes; Deoxyglucose; Fermentation; Ferricyanides; Glucose; Oxygen; Peptostreptococcus; Proline | 1987 |
Mechanistic implications of the inhibition of peptidases by amino aldehydes and bestatin.
Topics: Alanine; Aldehydes; Aminopeptidases; Animals; Aspartic Acid Endopeptidases; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Kidney; Kinetics; Leucine; Leucyl Aminopeptidase; Male; Peptide Hydrolases; Proline; Protease Inhibitors; Rats; Testis | 1985 |
Cytochemical localization and biochemical evaluation of a lysosomal serine protease in lung: dipeptidyl peptidase II in the normal rat.
Topics: 2-Naphthylamine; Alanine; Animals; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Histocytochemistry; Isoelectric Focusing; Lung; Lysine; Lysosomes; Male; Microscopy, Electron; Proline; Rats; Rats, Inbred Strains | 1985 |
[Variations of serum amino-acid spectrum in extra-hepatic obstructive jaundice and its clinical significance].
Topics: Adult; Aged; Alanine; Amino Acids; Amino Acids, Branched-Chain; Amino Acids, Essential; Cholestasis, Extrahepatic; Female; Humans; Male; Middle Aged; Parenteral Nutrition, Total; Proline | 1985 |
The effect of different types of physical exercise on glucose and citrulline synthesis in isolated rat liver parenchymal cells.
Topics: Alanine; Animals; Citrulline; Gluconeogenesis; Glucose; Lactates; Liver; Male; Physical Exertion; Proline; Pyruvates; Rats; Rats, Inbred Strains | 1986 |
Glucose intolerance and amino acid imbalance in relation to changes in blood ketone body ratio in hepatectomized rabbits.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Amino Acids; Animals; Blood Glucose; Cholestasis, Extrahepatic; Common Bile Duct; Fatty Acids, Nonesterified; Glucose; Glucose Solution, Hypertonic; Hepatectomy; Hydroxybutyrates; Ketone Bodies; Ligation; Male; Proline; Rabbits | 1986 |
17O NMR investigation of the hydration of L-alanine and L-proline in water/Me2SO mixtures.
Topics: Alanine; Dimethyl Sulfoxide; Hydrogen Bonding; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Oxygen Isotopes; Proline; Water | 1986 |
[Alanine metabolism in the skeletal muscle and plasma in endotoxemia].
Topics: Alanine; Animals; Glycine; Muscles; Proline; Rabbits; Sepsis; Shock, Septic | 1985 |
Sequential changes in blood concentrations of fuels in relation to arterial blood ketone body ratio after 70% hepatectomy in rabbits.
Topics: Alanine; Animals; Blood Glucose; Energy Metabolism; Fatty Acids, Nonesterified; Hepatectomy; Ketone Bodies; Male; Proline; Rabbits; Time Factors | 1985 |
Increased dependence of leucine in posttraumatic sepsis: leucine/tyrosine clearance ratio as an indicator of hepatic impairment in septic multiple organ failure syndrome.
Topics: Adolescent; Adult; Alanine; Amino Acids; Amino Acids, Essential; Aspartic Acid; Glutamates; Humans; Leucine; Liver; Metabolic Clearance Rate; Multiple Organ Failure; Muscles; Proline; Sepsis; Tyrosine; Wounds and Injuries | 1985 |
Uptake of proline by brushborder vesicles isolated from human kidney cortex.
Topics: Alanine; Glycine; Humans; Hydroxyproline; In Vitro Techniques; Kidney Cortex; Kidney Tubules, Proximal; Kinetics; Microvilli; Proline | 1985 |
Osmoregulation in the stenohaline crab "Libinia emarginata" Leech.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chlorides; Crustacea; Glutamates; Glycine; Hypotonic Solutions; Muscles; Potassium; Proline; Seawater; Sodium; Water-Electrolyte Balance | 1970 |
Immunological studies on the major haptenic peptides from performic acid oxidized ferredoxin from Clostridium pasteurianum.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Antibody Formation; Antigens; Aspartic Acid; Binding Sites; Carbon Isotopes; Clostridium; Complement Fixation Tests; Complement System Proteins; Dialysis; Electrophoresis; Epitopes; Ferredoxins; Formates; Glutamates; Glutamine; Haptens; Immune Sera; Immunoglobulin G; Isoleucine; Lysine; Oxidation-Reduction; Peptides; Proline; Rabbits; Serine; Tyrosine; Valine | 1971 |
Axonal transport of proteins in retinal ganglion cells. Amino acid incorporation into rapidly transported proteins and distribution of radioactivity to the lateral geniculate body and the superior colliculus.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Axonal Transport; Cysteine; Female; Geniculate Bodies; Glycine; Histidine; Leucine; Lysine; Male; Methionine; Nerve Tissue Proteins; Optic Nerve; Phenylalanine; Proline; Rabbits; Retina; Superior Colliculi; Tritium; Tryptophan | 1972 |
Contribution of different cell types to the genetic control of immune responses as a function of the chemical nature of the polymeric side chains (poly-L-prolyl and poly-DL-alanyl) of synthetic immunogens.
Topics: Alanine; Animals; Antibody-Producing Cells; Antigens; Bone Marrow; Bone Marrow Cells; Epitopes; Erythrocytes; Female; Glutamine; Hemagglutination Tests; Immunogenetics; Lysine; Male; Methods; Mice; Mice, Inbred Strains; Peptides; Phenylalanine; Polymers; Proline; Sheep; Spleen; Thymus Gland; Tyrosine | 1972 |
Cooperation of antigenic determinants in intact mice and interference by antigenic competition.
Topics: Alanine; Animals; Antibody Formation; Antigen-Antibody Reactions; Antigens; Carrier Proteins; Epitopes; Glutamates; Hemagglutination Tests; Lysine; Mice; Mice, Inbred C3H; Peptides; Phenylalanine; Proline; Tyrosine | 1972 |
Studies on the enzymes involved in the biosynthesis of cyclo-tris (N-2,3-dihydroxybenzoyl-L-seryl) in Escherichia coli: kinetic properties of the L-serine-activating enzyme.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Anti-Bacterial Agents; Drug Stability; Enzyme Induction; Escherichia coli; Ethylmaleimide; Glycine; Gramicidin; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Phosphates; Phosphorus Radioisotopes; Proline; Serine; Threonine; Time Factors; Tritium; Tyrosine | 1973 |
Antibody response of inbred mouse strains to ordered tetrapeptides of tyrosine and glutamic acid attached to multichain polyalanine or polyproline. Tyr-Tyr-Glu-Glu is a major determinant of the random poly-(Tyr, Glu)-polyDLAla--polyLys.
Topics: Alanine; Animals; Antibody Formation; Antibody Specificity; Cross Reactions; Epitopes; Glutamates; Hemagglutination Tests; Immunity; Mice; Mice, Inbred AKR; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred Strains; Oligopeptides; Proline; Tyrosine | 1974 |
Quantitative determination of secondary amines: measurement of N-methylalanine.
Topics: Acetaldehyde; Alanine; Amines; Ferricyanides; Hydrogen-Ion Concentration; Hydroxyproline; Indicators and Reagents; Ketones; Methylamines; Nitric Oxide; Proline; Spectrophotometry; Staining and Labeling; Sulfhydryl Compounds; Time Factors | 1974 |
Dynamics of axoplasmic transport in the optic system of the rat.
Topics: Alanine; Animals; Asparagine; Axonal Transport; Circadian Rhythm; Estrus; Female; Leucine; Male; Neurons; Pregnancy; Proline; Rats; Retina; Sex Factors; Solubility; Time Factors; Tritium; Visual Pathways | 1974 |
Immunological unresponsiveness induced in adult mice to synthetic polypeptides built on multichain polyproline and multichain polyalanine.
Topics: Alanine; Animals; Antibody Formation; Antigens; Epitopes; Female; Freund's Adjuvant; Hemagglutination Tests; Hemolytic Plaque Technique; Immune Tolerance; Immunity; Immunosuppression Therapy; Injections, Intraperitoneal; Male; Mice; Peptides; Proline | 1974 |
Hydroxy-L-proline as a substrate for hog kidney D-amino acid oxidase.
Topics: Alanine; Animals; Chromatography, Ion Exchange; Chromatography, Thin Layer; D-Amino-Acid Oxidase; Dialysis; Hydrogen-Ion Concentration; Hydroxyproline; Isomerism; Kidney; Kinetics; Proline; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Swine; Time Factors | 1974 |
Distinct components of neutral amino acid transport in chick small intestine.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Chickens; Glycine; Intestinal Absorption; Intestine, Small; Leucine; Male; Proline; Tryptophan | 1974 |
Spontaneous and induced generation of optical activity in racemic 1,1'-binaphthyl.
Topics: Alanine; Butanols; Chlorates; Cholesterol; Crystallization; Malates; Mandelic Acids; Naphthols; Nicotine; Optical Rotation; Phenylalanine; Proline; Stereoisomerism; Strychnine; Tartrates | 1974 |
Nature of the gastric secretagogue in Zollinger-Ellison tumours.
Topics: Alanine; Aspartic Acid; Gastrins; Glutamates; Glycine; Humans; In Vitro Techniques; Leucine; Methionine; Proline; Spectrum Analysis; Tryptophan; Tyrosine; Zollinger-Ellison Syndrome | 1967 |
Plasma-aminoacid levels in Huntington's chorea.
Topics: Adult; Alanine; Amino Acids; Female; Humans; Huntington Disease; Isoleucine; Leucine; Male; Middle Aged; Proline; Schizophrenia; Tyrosine; Valine | 1969 |
Regulation of the -methylgalactoside transport system and the galatose-binding protein by the cell cycle of Escherichia coli.
Topics: Alanine; Alkaline Phosphatase; Autoradiography; Bacterial Proteins; Carbon Isotopes; Cell Division; Culture Media; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Galactose; Galactosidases; Immunodiffusion; Lactose; Leucine; Mutation; Proline; Protein Binding; Temperature; Transduction, Genetic | 1973 |
Role of methionine in biosynthesis of prodigiosin by Serratia marcescens.
Topics: Alanine; Aspartic Acid; Carbon Radioisotopes; Cell-Free System; Chemical Phenomena; Chemistry; Culture Media; Escherichia coli; Glutamates; Histidine; Methionine; Methyltransferases; Mutation; Prodigiosin; Proline; Pseudomonas aeruginosa; S-Adenosylmethionine; Serine; Serratia marcescens; Stereoisomerism; Tetrahydrofolates | 1973 |
[Hyperiminoaciduria and disaminoaciduria in endemic (Balkan-)nephropathy (author's transl)].
Topics: Adult; Aged; Alanine; Amino Acids; Chromatography, Thin Layer; Chronic Disease; Creatinine; Female; Glycine; Humans; Hydroxyproline; Imino Acids; Kidney Failure, Chronic; Male; Middle Aged; Nephritis, Interstitial; Nitrogen; Proline; Syndrome; Uric Acid | 1974 |
Haemoglobin Madrid beta 115 (G17) alanine--proline: an unstable variant associated with haemolytic anaemia.
Topics: Adolescent; Alanine; Amino Acid Sequence; Amino Acids; Anemia, Hemolytic; Blood Protein Electrophoresis; Blood Transfusion; Cellulose; Chromatography, Gel; Dansyl Compounds; Electrophoresis, Paper; Electrophoresis, Starch Gel; Fetal Hemoglobin; Globins; Heinz Bodies; Hemoglobins, Abnormal; Humans; Male; Peptides; Proline; Spain; Trypsin | 1974 |
D-amino acids in the cell pool of bacteria.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Bacillus subtilis; Bacteria; Chromatography, Thin Layer; Clostridium; Culture Media; Escherichia coli; Glutamates; Histidine; Hydrogen-Ion Concentration; Lactobacillus; Leucine; Proline; Serine; Spectrophotometry; Staphylococcus; Stereoisomerism; Temperature; Tyrosine | 1974 |
Effect of ultraviolet radiations on ornithine.
Topics: Alanine; Aminobutyrates; Ammonia; Bicarbonates; Chemical Phenomena; Chemistry; Chromatography; Indenes; Indicators and Reagents; Ketones; Ornithine; Proline; Radiation Effects; Spectrophotometry; Time Factors; Ultraviolet Rays | 1970 |
[Plasma amino acid levels in children of patients with Huntington's chorea].
Topics: Adolescent; Adult; Alanine; Amino Acids; Child; Child, Preschool; Female; Humans; Huntington Disease; Isoleucine; Leucine; Male; Middle Aged; Proline; Schizophrenia; Tyrosine | 1972 |
Energization of active transport by Escherichia coli.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Aerobiosis; Alanine; Anaerobiosis; Arsenic; Biological Transport, Active; Cell Membrane; Dinitrophenols; Energy Transfer; Escherichia coli; Glutamates; Lactates; Leucine; Oxidative Phosphorylation; Phosphoenolpyruvate; Proline | 1972 |
The formation of glutamine and alanine in skeletal muscle.
Topics: Alanine; Amino Acids; Animals; Arteries; Diabetes Mellitus; Electric Stimulation; Fasting; Female; Glucagon; Glutamine; Glycine; Hindlimb; Humans; Insulin; Lactates; Methionine Sulfoximine; Muscles; Perfusion; Physical Exertion; Proline; Rats; Regional Blood Flow; Streptozocin; Valine; Veins | 1974 |
Characterization of avian leucosis group-specific antigen from avian myeloblastosis virus.
Topics: Alanine; Animals; Antigens; Autoanalysis; Avian Leukosis; Avian Leukosis Virus; Carbon Isotopes; Carboxypeptidases; Chromatography, Thin Layer; Complement Fixation Tests; Electrophoresis; Guanidines; Molecular Weight; Peptides; Proline; Trypsin; Ultracentrifugation | 1968 |
[Use of amino acids and pathogenic and non-pathogenic E. coli with increased resistance to a number of antibiotics in experiments in vitro and in the process of treatment of patients with colienteritis].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Child; Chloramphenicol; Chlortetracycline; Colistin; Drug Resistance, Microbial; Enteritis; Escherichia coli; Escherichia coli Infections; Glutamates; Glycine; Humans; In Vitro Techniques; Oxytetracycline; Proline; Serine; Streptomycin; Viomycin | 1967 |
Primary structure of insoluble tendon collagen. II. N- and C-terminal positional analysis of collagenolytic breakdown products of trypsin-pretreated collagen.
Topics: Achilles Tendon; Alanine; Amino Acids; Animals; Arginine; Cattle; Collagen; Glycine; Hydroxyproline; Isoleucine; Leucine; Methionine; Methods; Microbial Collagenase; Phenylalanine; Proline; Threonine; Trypsin; Tyrosine | 1968 |
Primary structure of insoluble tendon collagen. I. N- and C-terminal positional analysis of collagenolytic breakdown products of native collagen.
Topics: Achilles Tendon; Alanine; Amino Acids; Animals; Arginine; Cattle; Collagen; Glycine; Hydroxyproline; Isoleucine; Methods; Microbial Collagenase; Phenylalanine; Proline; Valine | 1968 |
Proline as an intermediate in the reductive deamination of ornithine to delta-aminovaleric acid.
Topics: Adenine Nucleotides; Alanine; Carbon Isotopes; Chromatography, Paper; Clostridium botulinum; Copper; Diphosphates; Ornithine; Oxidation-Reduction; Proline; Valerates | 1968 |
Identification and analysis of multiple glycine transport systems in isolated mammalian renal tubules.
Topics: Alanine; Animals; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Clostridium; Computers; Depression, Chemical; Dinitrophenols; Extracellular Space; Glycine; In Vitro Techniques; Kidney Tubules; Kinetics; Male; Microbial Collagenase; Ouabain; Oxygen Consumption; Proline; Protein Hydrolysates; Rabbits; Sodium | 1968 |
Amino acid transport by isolated mammalian renal tubules. II. Transport systems for L-proline.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Animals; Biological Transport, Active; Carbon Isotopes; Depression, Chemical; Glycine; Kidney Tubules; Kinetics; Microbial Collagenase; Mutation; Proline; Rabbits; Sodium; Time Factors | 1969 |
Electron paramagnetic resonance study of free radical products of the reaction of ninhydrin with amino acids, peptides and proteins.
Topics: Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Dipeptides; Electron Spin Resonance Spectroscopy; Ethanol; Free Radicals; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Lysine; Peptides; Phenylalanine; Proline; Proteins; Serine; Solutions; Tryptophan; Tyrosine; Valine | 1970 |
2,4-diaminovaleric acid: an intermediate in the anaerobic oxidation of ornithine by Clostridium sticklandii.
Topics: Acetates; Adenine Nucleotides; Alanine; Amino Acids; Carbon Isotopes; Chlorides; Chromatography; Clostridium; Coenzymes; Electrophoresis; Intrinsic Factor; Ketoglutaric Acids; Magnesium; NAD; Ornithine; Oxidation-Reduction; Proline; Valerates; Vitamin B 12 | 1970 |
Content, synthesis and collectability of amino acids in various structures of the brains of rhesus monkeys.
Topics: Alanine; Amino Acids; Aminobutyrates; Amygdala; Animals; Aspartic Acid; Behavior, Animal; Brain; Brain Chemistry; Carbon Isotopes; Caudate Nucleus; Central Nervous System; Cerebral Cortex; Glutamates; Glycine; Haplorhini; Hypothalamus; Isoleucine; Methods; Perfusion; Phenylalanine; Proline; Synaptic Transmission; Technology, Radiologic; Tyrosine; Valine | 1970 |
Quantitative differences in proline tRNA content of rat liver and granulation tissue.
Topics: Alanine; Albumins; Amino Acids; Animals; Carbon Isotopes; Chromatography; Granulation Tissue; Leucine; Liver; Male; Proline; Protein Biosynthesis; Rats; RNA, Transfer; Silicon Dioxide; Solubility; Tritium; Tyrosine | 1970 |
Adrenocorticotropin. Solid-phase synthesis of 1-19 -adrenocorticotropic hormone, alanyl- 1-19 -adrenocorticotropic hormone, and prolyl- 1-19 -adrenocorticotropic hormone and their adrenocorticotropic activity.
Topics: Adrenocorticotropic Hormone; Alanine; Amino Acids; Animals; Biological Assay; Biphenyl Compounds; Chromatography, Gel; Chromatography, Ion Exchange; Cyclohexanes; Electrophoresis; Formates; Imides; Peptides; Proline; Sheep | 1972 |
Coupling of energy to active transport of amino acids in Escherichia coli.
Topics: Adenosine Triphosphatases; Alanine; Alkanes; Biological Transport, Active; Carbon Isotopes; Cell Membrane; Electron Transport; Escherichia coli; Genetics, Microbial; Glucose; L-Lactate Dehydrogenase; Lactates; Mutation; NAD; Oxygen Consumption; Proline; Succinates; Sulfonic Acids | 1972 |
Bradykinin potentiating peptide PCA-Lys-Trp-Ala-Pro. An inhibitor of the pulmonary inactivation of bradykinin and conversion of angiotensin I to II.
Topics: Alanine; Alcohols; Angiotensin II; Animals; Benzyl Compounds; Biological Assay; Blood Pressure; Bradykinin; Capillary Permeability; Carboxylic Acids; Cats; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Countercurrent Distribution; Dogs; Drug Synergism; Formates; Glutamates; Guinea Pigs; Ileum; In Vitro Techniques; Ion Exchange Resins; Lung; Lysine; Male; Peptides; Proline; Pyrrolidinones; Rabbits; Rats; Snakes; Time Factors; Tryptophan; Venoms | 1971 |
Synaptic biochemistry of amino acids.
Topics: Alanine; Amino Acids; Amino Acids, Dicarboxylic; Amino Acids, Essential; Animals; Binding, Competitive; Brain; Carbon Radioisotopes; Cerebral Cortex; Glycine; Kinetics; Proline; Rats; Receptors, Neurotransmitter; Spinal Cord; Strychnine; Subcellular Fractions; Synaptic Transmission; Synaptosomes; Tritium | 1973 |
Hemoglobin Duarte: (alpha2beta2 62(E6)Ala leads to Pro): a new unstable hemoglobin with increased oxygen affinity.
Topics: Adult; Alanine; Amino Acid Sequence; Amino Acids; Anemia, Hemolytic; Cell Survival; Chromium Radioisotopes; Electrophoresis, Paper; Electrophoresis, Starch Gel; Erythrocyte Count; Fetal Hemoglobin; Globins; Hematocrit; Hemoglobinometry; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; Inclusion Bodies; Male; Pedigree; Peptides; Proline; Reticulocytes; Splenomegaly; Thalassemia | 1974 |
The isolation and the structure of new glycopeptide from blood group substances.
Topics: Acetamides; Alanine; Asparagine; Blood Group Antigens; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis, Paper; Galactosamine; Glucosamine; Glycopeptides; Humans; Optical Rotation; Oxidation-Reduction; Periodic Acid; Proline; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet | 1974 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Potassium-induced release of amino acids from cerebral cortex and spinal cord slices of the rat.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Carbon Radioisotopes; Cerebral Cortex; Glutamates; Glycine; Histidine; In Vitro Techniques; Lysine; Male; Membrane Potentials; Phenylalanine; Potassium; Proline; Rats; Sodium; Spinal Cord; Synaptic Transmission; Synaptosomes; Tritium; Tyrosine | 1974 |
Isolation and characterization of a hydroxyproline-containing protein from soluble extracts of the leaves of sandal (Santalum album L.).
Topics: Alanine; Arabinose; Arginine; Aspartic Acid; Carbohydrates; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Galactose; Glutamates; Glycine; Glycoproteins; Hydrolysis; Hydroxyproline; Lysine; Microbial Collagenase; Molecular Weight; Plant Extracts; Plant Proteins; Plants; Proline; Pronase | 1974 |
Amino acid sequence of an alkaline proteinase inhibitor (Streptomyces subtilisin inhibitor) from Streptomyces albogriseolus S-3253.
Topics: Alanine; Amino Acid Sequence; Chymotrypsin; Cyanogen Bromide; Leucine; Methylation; Microbial Collagenase; Proline; Streptomyces; Subtilisins; Thermolysin; Threonine; Trypsin; Trypsin Inhibitors | 1974 |
[Further studies on amino acid sequence of proteins in tobacco mosaic virus].
Topics: Alanine; Amino Acid Sequence; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis; Glutamates; Leucine; Peptides; Proline; Threonine; Tobacco Mosaic Virus; Valine; Viral Proteins | 1965 |
Synthesis of [1-Isoleucine-, 3-proline-, and 5-alanine]-angiotensins. II.
Topics: Alanine; Angiotensin II; Animals; Biological Assay; Chemical Phenomena; Chemistry; Female; Ganglionic Blockers; Isoleucine; Oxytocics; Peptides; Proline; Rats; Uterus; Vagotomy; Vasoconstrictor Agents | 1968 |
Kinetic behavior of D-amino acid oxidase in its reaction with basic amino acids.
Topics: Alanine; Amino Acids; Arginine; D-Amino-Acid Oxidase; In Vitro Techniques; Kinetics; Leucine; Phenylalanine; Proline; Valine | 1970 |
Release of alpha imino acid as primary product in D-amino-acid oxidase reaction.
Topics: Alanine; Chemical Phenomena; Chemistry; D-Amino-Acid Oxidase; Hydrogen-Ion Concentration; Imines; Leucine; Oxygen Consumption; Proline | 1970 |
Hydroxyproline in the allantoic fluid of the mare.
Topics: Adrenergic beta-Agonists; Alanine; Animals; Body Fluids; Chromatography; Female; Glutamates; Glycine; Horses; Hydroxyproline; Indicators and Reagents; Indoles; Ion Exchange Resins; Kidney; Liver; Pregnancy; Proline | 1970 |
Studies on the mechanism of action of D-amino acid oxidase. Evidence for removal of substrate -hydrogen as a proton.
Topics: Alanine; Chemical Phenomena; Chemistry; Chlorine; D-Amino-Acid Oxidase; Deuterium; Flavin-Adenine Dinucleotide; Hydrogen; Hydrogen-Ion Concentration; Keto Acids; Kinetics; Models, Chemical; Nitrogen; Oxygen; Phenylhydrazines; Proline; Protons; Pyruvates; Quaternary Ammonium Compounds; Serine; Spectrophotometry; Stereoisomerism; Thiosemicarbazones; Tritium; Ultraviolet Rays | 1971 |
Control of glutamine synthesis in rat liver.
Topics: Alanine; Amino Acids; Ammonia; Animals; Brain; Cyanides; Female; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Hydroxylysine; In Vitro Techniques; Liver; Methionine Sulfoximine; Perfusion; Proline; Rats; Starvation | 1971 |
Isolation and identification of pharmacologically active amino acids in skin and their structure-activity relationship on the guinea-pig ileum.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Atropine; Chromatography, Ion Exchange; Esters; Guinea Pigs; Histamine H1 Antagonists; Humans; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Proline; Rabbits; Rats; Receptors, Drug; Serine; Skin; Structure-Activity Relationship; Tissue Extracts | 1972 |
Specific cleavage between variable and constant domains of rabbit antibody light chains by dilute acid hydrolysis.
Topics: 1-Propanol; Acetates; Alanine; Alkylation; Amino Acid Sequence; Amino Acids; Animals; Antibodies, Bacterial; Aspartic Acid; Chemical Phenomena; Chemistry; Chromatography, Gel; Glutamine; Guanidines; Hydrogen-Ion Concentration; Hydrolysis; Immunoglobulin Fragments; Oxidation-Reduction; Polysaccharides, Bacterial; Proline; Pyridines; Pyrrolidonecarboxylic Acid; Rabbits; Streptococcus pneumoniae; Thiocyanates; Time Factors | 1972 |
Physiology of interferonogenesis. 3. Effect of DL-ornithine on interferonogenesis in chick embryo fibroblasts.
Topics: Alanine; Animals; Arginine; Cells, Cultured; Chick Embryo; Chikungunya virus; Fibroblasts; Glutamates; Glutamine; Hemagglutination Inhibition Tests; Immune Sera; Interferon Inducers; Interferons; Ketoglutaric Acids; Ornithine; Orthomyxoviridae; Proline; Rabbits; Stereoisomerism; Time Factors; Valine; Vesicular stomatitis Indiana virus; Virus Replication | 1973 |
A novel approach for studies of the molecular conformations in flexible polypeptides.
Topics: Alanine; Calorimetry; Carbon Isotopes; Deuterium; Dimethyl Sulfoxide; Evaluation Studies as Topic; Kinetics; Magnetic Resonance Spectroscopy; Methods; Oligopeptides; Peptides; Phenylalanine; Proline; Protein Conformation; Structure-Activity Relationship; Thermodynamics | 1974 |
Utilization of amino acids as nitrogen sources, and their effects on nitrate reductase in the marine diatom Cyclotella cryptica.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Asparagine; Cell-Free System; Chlorophyll; Eukaryota; Glutamates; Glutamine; Glycine; Isoleucine; Nitrate Reductases; Nitrates; Ornithine; Plant Proteins; Proline; Seawater; Urea; Water Microbiology | 1974 |
Uptake of amino acids by the marine centric diatom Cyclotella cryptica.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Autoradiography; Biological Transport, Active; Carbon Radioisotopes; Chromatography, Paper; Cyanides; Depression, Chemical; Dinitrophenols; Eukaryota; Glutamates; Isoleucine; Kinetics; Nitrogen; Ornithine; Proline; Seawater; Temperature; Water Microbiology | 1974 |
[Amino acid levels in the blood serum of patients with chronic colitis].
Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Betaine; Chronic Disease; Citrulline; Colitis; Glutamates; Glutamine; Glycine; Histidine; Humans; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tryptophan; Tyrosine; Urea | 1974 |
Amino acid transport in human placental slices.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Biological Transport, Active; Carbon Radioisotopes; Chromatography, Paper; Extracellular Space; Female; Glutamates; Glycine; Humans; In Vitro Techniques; Kidney; Leucine; Lysine; Placenta; Pregnancy; Proline; Rats; Serine; Time Factors | 1974 |
Free amino acid levels in the boll weevil (Coleoptera: Curculionidae): the effect of five different diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography, Gas; Coleoptera; Diet; Dietary Proteins; Glutamates; Glycine; Gossypium; Histidine; Isoleucine; Leucine; Male; Mass Spectrometry; Methionine; Phenylalanine; Proline; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
The far-infrared properties of polyamino acids.
Topics: Absorption; Alanine; Amino Acid Sequence; Amino Acids; Caseins; Leucine; Mathematics; Myoglobin; Oligopeptides; Ovalbumin; Peptides; Proline; Solutions; Solvents; Spectrophotometry, Infrared; Temperature | 1974 |
Free amino acids in the haemocytes and plasma of the larva of Calliphora vicina.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Blood Cells; Blood Coagulation; Diptera; Glutamates; Glutamine; Glycine; Hemolymph; Histidine; Isoleucine; Larva; Leucine; Lysine; Methionine; Phenylalanine; Plasma; Proline; Serine; Taurine; Threonine; Tyrosine; Valine | 1974 |
Study of serum amino acids in Egyptian lead workers.
Topics: Adult; Alanine; Amino Acids; Colorimetry; Egypt; Glutamates; Glycine; Histidine; Humans; Lead Poisoning; Leucine; Lysine; Male; Middle Aged; Proline; Serine; Tyrosine; Valine | 1974 |
The structural code for proteins: zonal distribution of amino acid residues and stabilization of helices by hydrophobic triplets.
Topics: Alanine; Amino Acids; Aspartic Acid; Computers; Isoleucine; Leucine; Mathematics; Models, Molecular; Proline; Protein Conformation; Statistics as Topic; Tyrosine; Valine | 1974 |
Studies on the fractionation of total transfer ribonucleic acid and purification of an alanine transfer ribonucleic acid from chick embryo.
Topics: Alanine; Animals; Aspartic Acid; Chemical Fractionation; Chick Embryo; Chromatography, Ion Exchange; Histidine; Isoleucine; Lysine; Proline; Ribonucleases; RNA, Transfer; Serine; Tyrosine; Valine | 1974 |
Nitrogen components reaching the omasum and abomasum of lambs fed two nitrogen levels.
Topics: Abomasum; Alanine; Amino Acids; Amino Acids, Essential; Animal Feed; Animals; Glycine max; Male; Nitrogen; Omasum; Proline; Sheep; Threonine; Valine | 1974 |
Enzymatic properties of pig intestinal proline dipeptidase.
Topics: Alanine; Animals; Dipeptidases; Glycine; Hot Temperature; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Intestines; Isoflurophate; Kinetics; Mercaptoethanol; Phenanthrolines; Proline; Swine; Time Factors | 1974 |
Mode of action on proteins of acid carboxypeptidase from Aspergillus saitoi.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Aspergillus; Carboxypeptidases; Cattle; Egg White; Hydrogen-Ion Concentration; Kinetics; Methods; Muramidase; Phenylalanine; Proline; Proteins; Ribonucleases; Serine; Surface-Active Agents; Time Factors; Valine | 1974 |
Amino acid and glucose uptake by the isolated perfused guinea-pig mammary gland.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Radioisotopes; Caseins; Female; Glucose; Glutamates; Guinea Pigs; Lactation; Mammary Glands, Animal; Organ Size; Perfusion; Pregnancy; Proline; Serine; Time Factors | 1974 |
Prebiotic synthesis of hydrophobic and protein amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Ammonia; Aspartic Acid; Autoanalysis; Chromatography, Gas; Glutamates; Glycine; Isoleucine; Leucine; Mass Spectrometry; Methane; Nitrogen; Proline; Serine; Threonine; Valine; Water | 1972 |
Conformational changes and inhibitor binding at the active site of elastase.
Topics: Alanine; Animals; Benzoates; Binding Sites; Crystallization; Fluorine; Glutathione; Hydrogen-Ion Concentration; Hydrolysis; Iodine; Lysine; Methanol; Molecular Conformation; Pancreas; Pancreatic Elastase; Peptides; Phenylalanine; Proline; Protein Binding; Protein Conformation; Structure-Activity Relationship; Sulfonic Acids; Swine; Tosyl Compounds; X-Ray Diffraction | 1972 |
Accumulation and transport of amino acids by the frog choroid plexus.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Anura; Biological Transport, Active; Carbon Isotopes; Choroid Plexus; Glutamates; Glycine; Inulin; Leucine; Mannitol; Potassium; Proline; Rana catesbeiana; Sodium | 1972 |
Antigenic competition and genetic control of the immune response. A hypothesis for intramolecular competition.
Topics: Alanine; Animals; Antibody Formation; Antigen-Antibody Reactions; Antigens; B-Lymphocytes; Glutamates; Hemagglutination Tests; Immunization; Immunogenetics; Lysine; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Peptide Chain Termination, Translational; Peptides; Phenylalanine; Poly A-U; Proline; T-Lymphocytes; Tyrosine | 1973 |
Cellular studies of the genetic control of immune response toward the loop region of lysozyme.
Topics: Alanine; Animals; Antibodies; Antibody Formation; B-Lymphocytes; Bone Marrow; Bone Marrow Cells; Female; Hemagglutination Tests; Histocompatibility; Immunization; Immunogenetics; Lymphocytes; Male; Mice; Mice, Inbred Strains; Muramidase; Peptides; Proline; Radiation Chimera; T-Lymphocytes; Thymus Gland | 1973 |
Rat-proinsulin C-peptides. Amino-acid sequences.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Autoanalysis; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Electrophoresis, Paper; Glutamine; Glycine; Papain; Pepsin A; Peptides; Proinsulin; Proline; Rats; Threonine; Trypsin | 1972 |
Biosynthesis of melittin, a toxic peptide from bee venom. Amino-acid sequence of the precursor.
Topics: Alanine; Amides; Amino Acid Sequence; Animals; Asparagine; Bees; Carbon Isotopes; Cathepsins; Chromatography, Paper; Electrophoresis, Paper; Exocrine Glands; Glutamates; Glutamine; Glycine; Hydrolysis; Pepsin A; Peptides; Proline; Protein Precursors; Threonine; Tritium; Trypsin; Venoms | 1973 |
Synthetic analogs of the hypothalamic luteinizing hormone releasing factor with increased agonist or antagonist properties.
Topics: Alanine; Animals; Biological Assay; Castration; Cells, Cultured; Chromatography, Gel; Chromatography, Thin Layer; Estradiol; Female; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Models, Structural; Molecular Conformation; Optical Rotation; Pituitary Gland; Proline; Rats; Structure-Activity Relationship; Valine | 1973 |
Changes of free amino acids in pancreatic beta-cells after starvation and substrate deprivation.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Carbon Radioisotopes; Chromatography, Thin Layer; Dansyl Compounds; Diabetes Mellitus; Fasting; Female; Freeze Drying; Glutamates; Glycine; Islets of Langerhans; Leucine; Lysine; Mice; Obesity; Ornithine; Phenylalanine; Proline; Taurine; Tritium; Valine | 1974 |
Incorporation of amino acid carbon into prodigiosin synthesized by nonproliferating cells of Serratia marcescens.
Topics: Alanine; Amino Acids; Bacterial Proteins; Carbon Radioisotopes; Prodigiosin; Proline; Serratia marcescens; Spectrophotometry, Ultraviolet; Stereoisomerism | 1974 |
Basis of transport discrimination of arginine from other basic amino acids in Salmonella typhimurium.
Topics: Alanine; Amino Acids; Arginine; Autoanalysis; Biological Transport; Carbon Radioisotopes; Chromatography, Ion Exchange; Deuterium; Glucose; Histidine; Homoserine; Hydroxyproline; Kinetics; Leucine; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Ornithine; Proline; Salmonella typhimurium; Structure-Activity Relationship; Tritium; Tryptophan | 1974 |
Exogenous carbon and nitrogen requirements for conidial germination by Aspergillus flavus.
Topics: Alanine; Amino Acids; Ammonium Chloride; Aspergillus; Aspergillus flavus; Carbon; Carbon Dioxide; Culture Media; Glucose; Glycine; Nitrogen; Proline; Spores; Spores, Fungal; Surface-Active Agents; Tryptophan | 1972 |
Parenteral nutrition with a solution of pure L-amino acids.
Topics: Adult; Alanine; Amino Acids; Arginine; Blood Urea Nitrogen; Creatinine; Glycine; Histidine; Humans; Male; Nitrogen; Parenteral Nutrition; Proline; Solutions | 1972 |
[Amino acids in parenteral feeding].
Topics: Alanine; Amino Acids; Arginine; Histidine; Homeostasis; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Nutrition Disorders; Parenteral Nutrition; Phenylalanine; Proline; Protein Conformation; Protein-Energy Malnutrition; Proteins; Threonine; Tryptophan; Valine | 1972 |
Transport of amino acids into the estrogen-primed uterus. 3. Effect of the level of extracellular sodium ion.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Carbon Isotopes; Cyclopentanes; Estradiol; Female; Kinetics; Models, Biological; Osmolar Concentration; Ouabain; Phenylalanine; Potassium; Proline; Rats; Sodium; Stimulation, Chemical; Uterus; Valine | 1972 |
Primary structures of the proinsulin connecting peptides of the rat and the horse.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Electrophoresis, Paper; Ethanol; Glutamates; Glycine; Horses; Hydrogen-Ion Concentration; Pancreas; Peptides; Proinsulin; Proline; Rats; Solubility; Species Specificity; Thiocyanates | 1972 |
Proline metabolism in Leishmania donovani promastigotes.
Topics: Alanine; Arginine; Aspartic Acid; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Glucose; Glutamates; Leishmania; Malate Dehydrogenase; Malates; Methionine; Methods; Oxygen Consumption; Proline; Pyruvates; Serine | 1972 |
Synthesis of sequence peptide polymers related to collagen.
Topics: Alanine; Amino Acid Sequence; Collagen; Glycine; Hydroxyproline; Methods; Peptides; Polymers; Proline; Serine | 1972 |
Permeability of human buccal mucosa to an amino acid analogue, the antibiotic D-cycloserine.
Topics: Alanine; Cheek; Cycloserine; Humans; Hydrogen-Ion Concentration; Methionine; Mouth Mucosa; Proline; Serine | 1972 |
[Amino acid metabolism pathology in the convulsive syndrome in young children].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Child, Preschool; Cystine; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Infant; Infant, Newborn; Leucine; Lysine; Male; Methionine; Proline; Seizures; Serine; Tryptophan; Tyrosine; Valine | 1972 |
Schistosoma mansoni and Schistosoma japonicum: utilization of amino acids.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Biomphalaria; Carbon Dioxide; Carbon Isotopes; Female; Glutamates; Histidine; Male; Mice; Proline; Schistosoma; Schistosoma mansoni; Sex Factors; Snails; Species Specificity; Tyrosine | 1972 |
Studies on protamines. XVI. The complete amino acid sequence of clupeine YII.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Chromatography; Fishes; Male; Proline; Protamines; Serine; Spermatozoa; Threonine; Valine | 1972 |
Studies on protamines. XVII. The complete amino acid sequence of clupeine YI.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Cell Nucleus; Chromatography; Fishes; Glycine; Isoleucine; Male; Proline; Protamines; Serine; Spermatozoa; Threonine | 1972 |
Sequential polypeptides. IV. The synthesis of poly-(L-alanylglycyl-L-proline) and its stereoisomers.
Topics: Alanine; Amino Acid Sequence; Chromatography, Gel; Glycine; Magnetic Resonance Spectroscopy; Molecular Weight; Optical Rotation; Peptides; Proline; Spectrophotometry, Infrared; Stereoisomerism; Viscosity | 1972 |
Interaction of 4-nitroquinoline 1-oxide and related carcinogens with histone and aliphatic amino acids.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carcinogens; Cattle; Chemical Phenomena; Chemistry; Glutamates; Glycine; Histones; Isoleucine; Leucine; Lysine; Methionine; Proline; Protein Denaturation; Quinolines; Serine; Spectrophotometry; Threonine; Thymus Gland; Valine | 1972 |
Raman spectroscopy.
Topics: Alanine; Amides; Evaluation Studies as Topic; Glutamates; Glycine; Lasers; Leucine; Mathematics; Methods; Muramidase; Peptides; Proline; Protein Conformation; Spectrophotometry, Ultraviolet; Spectrum Analysis | 1972 |
Specific transfer process for intestinal absorption of peptides.
Topics: Alanine; Animals; Dipeptides; Glycine; Intestinal Absorption; Leucine; Methionine; Proline; Rats | 1973 |
The effect of intravenous glucagon on plasma amino acids in the newborn.
Topics: Alanine; Amino Acids; Birth Weight; Blood Glucose; Female; Gestational Age; Glucagon; Gluconeogenesis; Glucose; Growth Hormone; Humans; Infant, Newborn; Injections, Intravenous; Insulin; Methods; Pregnancy; Pregnancy in Diabetics; Proline; Stimulation, Chemical | 1973 |
The reversal of triparanol-induced cataracts in the rat. 3. Amino acid content and uptake of 14 C -AIB in cataractous and clearing lenses.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Cataract; Cystine; Diet; Glutamates; Glycine; Histidine; Isoleucine; Lens, Crystalline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Serine; Threonine; Triparanol; Tyrosine; Valine | 1973 |
The amino-acid composition of human hard tissue collagens in osteogenesis imperfecta and dentinogenesis imperfecta.
Topics: Alanine; Amino Acids; Bone and Bones; Child; Collagen; Dentin; Dentinogenesis Imperfecta; Glycine; Humans; Hydroxylysine; Hydroxyproline; Infant, Newborn; Male; Molar; Osteogenesis Imperfecta; Proline; Skull | 1973 |
The free and bound amino acids removed by hemodialysis.
Topics: Adult; Alanine; Amino Acids; Asparagine; Aspartic Acid; Blood Flow Velocity; Blood Glucose; Body Weight; Cystine; Fasting; Female; Freeze Drying; Glucose; Glutamine; Glycine; Humans; Hydrolysis; Kidneys, Artificial; Male; Methionine; Middle Aged; Molecular Weight; Proline; Renal Dialysis; Uremia | 1973 |
Biosynthesis of ergotamine by Claviceps purpurea (Fr.) Tul.
Topics: Acetates; Alanine; Amino Acids; Carbon Isotopes; Cells, Cultured; Chromatography, Ion Exchange; Chromatography, Thin Layer; Culture Media; Electrophoresis, Paper; Ergotamine; Formates; Hydrogen-Ion Concentration; Isomerism; Methionine; Mevalonic Acid; Phenylalanine; Plants; Proline; Spectrophotometry, Ultraviolet; Tryptophan | 1973 |
The antigenicity of sequential polypeptides. I. The synthesis of some sequential collagen models.
Topics: Acetates; Alanine; Antigens; Bromides; Chromatography, Gel; Collagen; Esters; Glycine; Heating; Molecular Weight; Nitrophenols; Optical Rotation; Peptides; Proline; Protein Conformation | 1973 |
The antigenicity of sequential polypetides. II. The antigenicity of some sequential polymers including several related to collagen.
Topics: Alanine; Amino Acid Sequence; Animals; Antibody Formation; Antigens; Collagen; Cross Reactions; Glycine; Guinea Pigs; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Immunization; Molecular Weight; Peptides; Proline; Skin Tests | 1973 |
Peptide chloromethyl ketones as irreversible inhibitors of elastase.
Topics: Acetates; Alanine; Alkylation; Amino Acids; Animals; Benzyl Compounds; Chemical Phenomena; Chemistry; Chlorine; Formates; Histidine; Ketones; Oligopeptides; Oxidation-Reduction; Pancreas; Pancreatic Elastase; Proline; Swine | 1973 |
Use of peptide aldehydes to generate transition-state analogs of elastase.
Topics: Acetates; Alanine; Alcohols; Aldehydes; Amino Alcohols; Animals; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Hydrolysis; Oligopeptides; Oxidation-Reduction; Pancreas; Pancreatic Elastase; Proline; Protein Binding; Swine | 1973 |
Restrictions on the binding of proline-containing peptides to elastase.
Topics: Alanine; Amides; Animals; Binding Sites; Butanols; Chromatography, Thin Layer; Esters; Formates; Hydrolysis; Kinetics; Mathematics; Oligopeptides; Pancreas; Pancreatic Elastase; Proline; Protein Binding; Structure-Activity Relationship; Succinimides; Swine | 1973 |
Dependence of the kinetic parameters for elastase-catalyzed amide hydrolysis on the length of peptide substrates.
Topics: Acetates; Acylation; Alanine; Amides; Animals; Binding Sites; Butanols; Chromatography, Thin Layer; Formates; Hydrolysis; Kinetics; Oligopeptides; Pancreas; Pancreatic Elastase; Proline; Protein Binding; Structure-Activity Relationship; Swine | 1973 |
Elastase-catalyzed amide hydrolysis of tri- and tetrapeptide amides.
Topics: Acetates; Alanine; Amides; Animals; Binding Sites; Butyrates; Hydrolysis; Kinetics; Models, Structural; Oligopeptides; Pancreas; Pancreatic Elastase; Proline; Propionates; Protein Binding; Structure-Activity Relationship; Swine; Thermodynamics | 1973 |
Hybrid formation between collagen and synthetic polypeptides.
Topics: Alanine; Amino Acids; Animals; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Collagen; Glycine; Hybridization, Genetic; Molecular Conformation; Molecular Weight; Optical Rotation; Peptides; Proline; Protein Binding; Protein Conformation; Protein Denaturation; Rabbits; Serine; Skin; Temperature; Tropomyosin | 1973 |
A study of the reaction of monomers in high and low temperature conformational states of D-amino acid oxidase with substrates and quasi-substrates.
Topics: Alanine; Animals; Benzoates; Isomerism; Methionine; Proline; Protein Conformation; Swine; Temperature | 1973 |
The content of several amino acids in the external cell sheath and four giant axons of a nerve bundle from the CNS of the lobster.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Axons; Brain; Cell Membrane; Central Nervous System; Ganglia; Glutamates; Glycine; Nephropidae; Proline | 1973 |
Effect of cortisol treatment on free amino acid levels in rats.
Topics: Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Glycine; Hydrocortisone; Liver; Male; Muscle Proteins; Muscles; Proline; Rats; Serine | 1973 |
Amino acid metabolism in chameleon tissues.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brain; Citrulline; Glutamates; Glutamine; Glycine; Histidine; Ketoglutaric Acids; Kidney; Liver; Lysine; Muscles; Myocardium; Ornithine; Oxaloacetates; Proline; Pyruvates; Reptiles; Serine; Tryptophan | 1973 |
Intestinal absorption of dipeptides containing glycine, phenylalanine, proline, beta-alanine or histidine in the rat.
Topics: Alanine; Animals; Blood Pressure; Catheterization; Chromatography, Ion Exchange; Dipeptides; Glycine; Histidine; Hydrolysis; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Male; Mesenteric Veins; Phenylalanine; Proline; Rats; Ultrasonics | 1973 |
The metabolism of amino acids in the bovine lens. Their oxidation as a source of energy.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Carbon Dioxide; Carbon Radioisotopes; Cattle; Collagen; Energy Metabolism; Glucose; Glutamates; Glutathione; In Vitro Techniques; Lactates; Lens, Crystalline; Leucine; Lipid Metabolism; Lysine; Oxidation-Reduction; Proline; Serine; Taurine; Tryptophan; Tyrosine | 1973 |
Biosynthetic precursors of etamycin, a peptidolactone antibiotic from Streptomyces griseoviridus.
Topics: Alanine; Anti-Bacterial Agents; Benzene Derivatives; Carbon Radioisotopes; Glucose; Hydroxyproline; Lactones; Leucine; Lysine; Nitrates; Peptides, Cyclic; Picolinic Acids; Potassium; Proline; Sarcosine; Streptomyces; Structure-Activity Relationship; Threonine; Tritium | 1973 |
Purification and specificity of pig intestinal prolidase.
Topics: Alanine; Animals; Binding Sites; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cross Reactions; Dipeptidases; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Hydroxyproline; Immunoelectrophoresis; Intestine, Small; Kinetics; Macromolecular Substances; Molecular Weight; Oligopeptides; Proline; Protein Binding; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Swine; Ultrafiltration | 1973 |
Metabolism of proline by the culture midgut form of Trypanosoma rhodesiense.
Topics: Alanine; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Citric Acid Cycle; Glutamates; Oxygen Consumption; Proline; Trypanosoma | 1973 |
Proline metabolism in Trypanosoma scelopori.
Topics: Alanine; Carbon Isotopes; Cyanides; Glucose; Glutamates; Hydroxyproline; Malonates; Oxygen Consumption; Proline; Trypanosoma | 1973 |
[Effect of the set of amino acids contained in casein, extracted soy bean meal, horse beans and wheat gluten on the content of leucine, isoleucine, valine, phenylalanine, tyrosine, glutamic acid, aspartic acid, alanine, glycine and proline in the deprotei
Topics: Alanine; Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Caseins; Chickens; Female; Glutamates; Glutens; Glycine; Glycine max; Isoleucine; Leucine; Phenylalanine; Plant Proteins; Proline; Triticum; Tyrosine; Valine | 1973 |
A lysine-rich protein from spermatozoa of the mollusc Mytilus edulis.
Topics: Alanine; Amino Acids; Animals; Arginine; Bivalvia; Chromatin; Chromatography, Gel; Chromatography, Paper; Electrophoresis, Paper; Histones; Hydrogen-Ion Concentration; Lysine; Male; Molecular Weight; Peptide Fragments; Proline; Protamines; Proteins; Serine; Spermatozoa; Thiocyanates; Trypsin | 1974 |
Folding of polypeptide chains induced by the amino acid side-chains.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Glycine; Leucine; Peptide Chain Elongation, Translational; Peptides; Phenylalanine; Probability; Proline; Protein Conformation; Structure-Activity Relationship | 1974 |
Levels of free amino acids in excitatory, inhibitory and sensory axons of the walking limbs of the lobster.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Axons; Glutamates; Glycine; Hemolymph; Motor Neurons; Muscles; Nephropidae; Proline | 1974 |
Increased taurine excretion in hereditary hyperprolinemia of the mouse.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Animals; Chromatography, Thin Layer; Glycine; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Proline; Taurine | 1974 |
An acetylated N-terminus of adenovirus type 2 hexon protein.
Topics: Acetylation; Adenoviridae; Alanine; Amino Acid Sequence; Carbon Radioisotopes; Chromatography, Ion Exchange; Electrophoresis, Paper; Hydrogen-Ion Concentration; Mass Spectrometry; Peptide Fragments; Proline; Serine; Threonine; Time Factors; Viral Proteins | 1974 |
Intracellular free amino acid concentration in human muscle tissue.
Topics: Adult; Alanine; Amino Acids; Arginine; Asparagine; Biopsy, Needle; Body Water; Chlorides; Citrulline; Extracellular Space; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Muscles; Ornithine; Phenylalanine; Proline; Serine; Taurine; Tyrosine; Valine | 1974 |
Spinal subarachnoid perfusion in the rat: glycine transport from spinal fluid.
Topics: Alanine; Aminobutyrates; Animals; Biological Transport; Carbon Radioisotopes; Female; Glycine; Inulin; Male; Mathematics; Perfusion; Proline; Rats; Spinal Cord; Subarachnoid Space; Taurine; Time Factors; Tritium | 1974 |
The optical properties of alanine and proline diketopiperazines.
Topics: Alanine; Circular Dichroism; Molecular Conformation; Optical Rotatory Dispersion; Piperazines; Proline; Solvents; Spectrophotometry, Ultraviolet | 1974 |
Arterial mesenchyme and arteriosclerosis. Studies on the conformation and interaction of elastin.
Topics: Alanine; Arteries; Arteriosclerosis; Calcium; Chemical Phenomena; Chemistry; Elastin; Glycine; Lipid Metabolism; Magnetic Resonance Spectroscopy; Microscopy, Electron; Peptides; Potassium; Proline; Temperature; Valine; Valinomycin; X-Ray Diffraction | 1974 |
A unique histidine-rich polypeptide from the malaria parasite, Plasmodium lophurae.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chromatography, Gel; Cytoplasmic Granules; Ducks; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Glutamates; Guanidines; Histidine; Hydrogen-Ion Concentration; Malaria; Microscopy, Electron; Peptides; Pigments, Biological; Plasmodium; Proline; Solubility | 1974 |
[Multiplicity of transport systems in the luminal membrane of the nephron in the normal rat].
Topics: Alanine; Animals; Biological Transport; Carbon Radioisotopes; Female; Glycine; Hydroxyproline; Imino Acids; Inulin; Kidney; Leucine; Membranes; Nephrons; Phenylalanine; Proline; Rats | 1974 |
[Synthesis of radioactive potential precursers of peptide moieties of ergotoxine alkaloids].
Topics: Alanine; Carbon Radioisotopes; Cyclization; Ergolines; Ergot Alkaloids; Esters; Glycine; Isotope Labeling; Lactams; Leucine; Methods; Peptides; Proline; Valine | 1974 |
Competition between carnosine and other peptides for transport by hamster jejunum in vitro.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Cricetinae; Dipeptides; Glutamates; Glycine; Histidine; Hydrolysis; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Jejunum; Lysine; Male; Methionine; Proline; Sarcosine | 1974 |
Conformational characteristics of polypeptides containing isolated L-proline residues with cis peptide bonds.
Topics: Alanine; Amino Acid Sequence; Glycine; Peptides; Proline; Protein Binding; Protein Conformation; Rotation | 1974 |
Free amino acids in developing rat retina.
Topics: Aging; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Chromatography, Ion Exchange; Glutamates; Glutamine; Glycine; Histidine; Methionine; Ornithine; Proline; Rats; Retina; Taurine; Time Factors; Tyrosine | 1974 |
The mean geometry of the peptide unit from crystal structure data.
Topics: Acetamides; Alanine; Crystallography; Glutathione; Glycine; Leucine; Models, Structural; Molecular Conformation; Oligopeptides; Phenylalanine; Proline; Protein Conformation; Tyrosine; X-Ray Diffraction | 1974 |
Altered amino acid concentrations accompanying suppression of malignancy of mouse melanoma cells by 5-bromodeoxyuridine.
Topics: Alanine; Amino Acids; Animals; Asparagine; Bromodeoxyuridine; Cells, Cultured; Glutamates; Glutamine; Glycine; Lysine; Melanoma; Methionine; Mice; Neoplasm Proteins; Ornithine; Phenylalanine; Pigmentation; Proline; Serine; Threonine; Valine | 1974 |
The amino acid sequences of some tryptic peptides from porcine pepsinogen.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Asparagine; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Enzyme Precursors; Glycine; Histidine; Leucine; Lysine; Pepsin A; Peptides; Proline; Swine; Trypsin; Valine | 1968 |
Control of carbon dioxide fixation in Escherichia coli by compounds related to TCA cycle.
Topics: Alanine; Arginine; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Cell-Free System; Citrates; Citric Acid Cycle; Coenzyme A; Depression, Chemical; Escherichia coli; Fumarates; Glutamates; Lactates; Lysine; Malates; Malonates; Ovalbumin; Proline; Pyruvates; Succinates; Tartrates; Threonine | 1968 |
Chemical studies on amino acid acceptor ribonucleic acids. 8. Degradation of purified alanine Escherichia coli B transfer ribonucleic acid by pancreatic ribonuclease.
Topics: Alanine; Alkalies; Chromatography, Ion Exchange; Chromatography, Paper; Countercurrent Distribution; Electrophoresis; Escherichia coli; Esterases; Hydrogen-Ion Concentration; Micrococcal Nuclease; Micrococcus; Pancreas; Proline; Ribonucleases; RNA, Transfer; Spectrophotometry; Urea; Venoms | 1969 |
Substrate specificity of ribosomal peptidyl transferase. The effect of the nature of the amino acid side chain on the acceptor activity of 2'(3')-O-aminoacyladenosines.
Topics: Acetates; Acyltransferases; Alanine; Amino Acids; Binding Sites; Carbon Isotopes; Escherichia coli; Glutamine; Glycine; Imidazoles; Leucine; Lysine; Methionine; Nucleosides; Peptides; Phenylalanine; Proline; Ribosomes; RNA, Transfer; Serine; Stereoisomerism; Valine | 1970 |
Induction of pigmentation in nonproliferating cells of Serratia marcescens by addition of single amino acids.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Aspartic Acid; Bacteriological Techniques; Caseins; Culture Media; Filtration; Glutamates; Ornithine; Pigments, Biological; Prodigiosin; Proline; Protein Hydrolysates; Pyrroles; Serine; Serratia marcescens; Stereoisomerism; Temperature | 1971 |
Inhibition of the alanine tRNA aminoacylation by Ca 2+ .
Topics: Alanine; Amino Acids; Amino Acyl-tRNA Synthetases; Calcium; Carbon Isotopes; Cysteine; Escherichia coli; Kinetics; Proline; RNA, Transfer; Transfer RNA Aminoacylation | 1971 |
Amino-acid protection of ultra-violet-irradiated Bacillus subtilis.
Topics: Acid-Base Equilibrium; Alanine; Bacillus subtilis; Culture Media; Glycine; Histidine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays | 1966 |
Species differences of serum amino acid beta-napthylamidases.
Topics: Alanine; Amides; Amino Acids; Aminopeptidases; Animals; Arginine; Chickens; Cyprinidae; Dipeptides; Dogs; Female; Glutamine; Glycine; Haplorhini; Humans; Isoleucine; Leucine; Lysine; Methionine; Mice; Naphthalenes; Phenylalanine; Proline; Rats; Serine; Species Specificity; Valine | 1968 |
"Dysgonic" strains of mycobacterium tuberculosis on Ogawa's egg medium isolated as pathogens from patients suffering from lung tuberculosis. II. Growth-inhibitory effects of D-asparagine, D-aspartic acid, Dl-serine, or L-serine against "dysgonic".
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Culture Media; Depression, Chemical; Glutamine; Histidine; Humans; Leucine; Mycobacterium tuberculosis; Proline; Serine; Tuberculosis, Pulmonary; Valine | 1967 |
[New findings on essential amino acids].
Topics: Alanine; Amino Acids; Humans; Parenteral Nutrition; Proline | 1968 |
Influence of carbon or nitrogen starvation on amino acid transport in Pseudomonas aeruginosa.
Topics: Alanine; Amino Acids; Biological Transport; Carbon; Carbon Isotopes; Chloramphenicol; Glutamates; Glycine; Histidine; Leucine; Nitrogen; Proline; Pseudomonas aeruginosa; Valine | 1969 |
Plasma amino acid levels in diabetic ketoacidosis.
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Arginine; Butyrates; Child; Citrulline; Cystine; Diabetic Ketoacidosis; Female; Glycine; Histidine; Humans; Insulin; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1970 |
The nutritive effect in man of non-essential amino acids infused intravenously (together with the essential ones). II. Different patterns of amino acids and different levels of nitrogen supply.
Topics: Adult; Alanine; Amino Acids; Arginine; Aspartic Acid; Female; Glycine; Histidine; Humans; Injections, Intravenous; Middle Aged; Nitrogen; Parenteral Nutrition; Proline; Time Factors; Urea | 1970 |
[Nitrogen metabolism in parenteral feeding].
Topics: Adult; Aged; Alanine; Amino Acids; Ammonia; Creatinine; Diet Therapy; Duodenal Ulcer; Female; Glycine; Humans; Male; Methionine; Middle Aged; Nitrogen; Parenteral Nutrition; Proline; Serine; Stomach Ulcer; Tryptophan; Urea | 1971 |
Synthesis of analogs of the thyrotropin-releasing hormone and structure-activity relationship.
Topics: Alanine; Amides; Animals; Benzyl Compounds; Biological Assay; Esters; Histidine; Leucine; Magnetic Resonance Spectroscopy; Mice; Peptides; Proline; Pyrrolidinones; Thyrotropin; Thyrotropin-Releasing Hormone; Valine | 1971 |
[Biochemical bases of parenteral nutrition with amino acids].
Topics: Alanine; Amino Acids; Dietary Proteins; Female; Glutamates; Humans; Male; Methionine; Nitrogen; Nutritional Requirements; Parenteral Nutrition; Proline; Solutions | 1971 |
[Studies on the nitrogen balance in parenteral nutrition].
Topics: Adult; Aged; Alanine; Amino Acids; Glutamates; Humans; Middle Aged; Nitrogen; Nutritional Requirements; Parenteral Nutrition; Proline | 1971 |
Optical activity of polypeptides and proteins.
Topics: Alanine; Chymotrypsin; Collagen; Models, Chemical; Muramidase; Myoglobin; Optical Rotatory Dispersion; Peptides; Proline; Proteins; Ribonucleases; Spectrum Analysis | 1972 |
Water relations of Salmonella oranienburg: accumulation of potassium and amino acids during respiration.
Topics: Alanine; Amino Acids; Aspartic Acid; Carbon Isotopes; Culture Media; Deamination; Glutamates; Oxidation-Reduction; Oxygen Consumption; Potassium; Proline; Salmonella; Staphylococcus; Water | 1972 |
Regulation of amino acid transport in chick embryo heart cells. I. Adaptive system of mediation for neutral amino acids.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Carbon Isotopes; Cells; Chick Embryo; Cycloheximide; Cyclopentanes; Dactinomycin; Glycine; Heart; Kinetics; Leucine; Myocardium; Phenylalanine; Proline; Puromycin; Time Factors | 1972 |
A basis for the difference in the inhibition of the uptake of various neutral amino acids by lysine in intestinal epithelial cells.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Carbon Isotopes; Epithelial Cells; Epithelium; Histidine; Intestinal Mucosa; Intestines; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Rats; Sodium; Threonine; Tryptophan; Valine | 1972 |
Circular dichroism of intramolecularly hydrogen-bonded acetylamino acid amides.
Topics: Acetates; Alanine; Amides; Amino Acids; Bradykinin; Chemical Phenomena; Chemistry; Circular Dichroism; Glycine; Methylamines; Optical Rotatory Dispersion; Peptides; Phenylalanine; Proline; Protein Conformation; Spectrophotometry; Tyrosine; Ultraviolet Rays | 1972 |
[Concentration changes of free amino acids in blood plasma of patients under radiotherapy. (With reference to statistical results)].
Topics: Alanine; Amino Acids; Bronchial Neoplasms; Carcinoma; Cobalt Isotopes; Dysgerminoma; Esophageal Neoplasms; Female; Genital Neoplasms, Female; Hodgkin Disease; Humans; Leucine; Male; Neoplasms; Phenylalanine; Proline; Radiation Injuries; Sex Factors; Statistics as Topic; Tyrosine; Urinary Bladder Neoplasms; Valine | 1972 |
[Free amino acids in the blood serum of patients with endemic (balkan) nephropathy].
Topics: Adult; Aged; Alanine; Amino Acids; Autoanalysis; Bulgaria; Female; Humans; Kidney Diseases; Male; Middle Aged; Nitrogen; Proline | 1972 |
Amino acid patterns in the blood plasma of the young bovine.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Cystine; Female; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1972 |
Transport of amino acids into the oestrogen-primed uterus. Enchancement of the uptake by a preliminary incubation.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Dinitrophenols; Estradiol; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Leucine; Phenylalanine; Potassium; Proline; Rats; Sodium; Time Factors; Uterus; Valine | 1972 |
Haemoglobin Denmark Hill 95 (G2) Pro-Ala, a variant with unusual electrophoretic and oxygen-binding properties.
Topics: Adult; Alanine; Amino Acid Sequence; Amino Acids; Electrophoresis, Paper; Electrophoresis, Starch Gel; Female; Gestational Age; Hemoglobinopathies; Hemoglobins; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Leucine; London; Molecular Biology; Mutation; Oxygen; Peptides; Pregnancy; Proline; Protein Binding; Serine | 1972 |
Invertebrate facultative anaerobiosis.
Topics: Adenosine Triphosphate; Alanine; Anaerobiosis; Animals; Ascaris; Carboxy-Lyases; Coenzyme A Ligases; Glucose; Glutamate Dehydrogenase; Glutamates; Helminths; Ketone Oxidoreductases; Malate Dehydrogenase; Mollusca; Ostreidae; Oxaloacetates; Proline; Pyruvate Kinase; Pyruvates; Succinate Dehydrogenase; Succinates | 1972 |
A general, highly efficient azeotropic method of esterification of amino acids.
Topics: Alanine; Amino Acids; Arginine; Benzene; Chemical Phenomena; Chemistry, Physical; Esters; Ethanol; Glycine; Hydrochloric Acid; Lysine; Methods; Proline; Temperature; Tyrosine; Water | 1971 |
Influence of urea, biuret and starch on amino acid patterns in ruminal bacteria and blood plasma and on nitrogen balance of steers fed high fiber purified diets.
Topics: Alanine; Amino Acids; Ammonia; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Bacteria; Cattle; Cellulose; Culture Media; Depression, Chemical; Diet; Dietary Carbohydrates; Digestion; Feces; Glutamates; Hydrolysis; Indenes; Isoleucine; Ketones; Male; Metabolism; Nitrogen; Proline; Rumen; Starch; Stimulation, Chemical; Time Factors; Urea; Urease; Valine; Wood; Zea mays | 1971 |
Transport of amino acids by rabbit choroid plexus in vitro.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Carbon Isotopes; Carrier Proteins; Choroid Plexus; Cold Temperature; Cyanides; Diffusion; Dinitrophenols; Glycine; Hydrogen-Ion Concentration; Hypoxia; Mathematics; Organ Culture Techniques; Ouabain; Proline; Rabbits; Sodium | 1971 |
Effect of excess levels of individual amino acids on growth of rats fed casein diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Caseins; Cystine; Depression, Chemical; Dietary Proteins; DNA; Glutamates; Glycine; Growth; Histidine; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Organ Size; Phenylalanine; Proline; Proteins; Rats; RNA; Serine; Stereoisomerism; Stimulation, Chemical; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Effect of dietary protein level on plasma free amino acids in the chicken.
Topics: Alanine; Amino Acids; Animals; Blood; Body Weight; Caseins; Chickens; Depression, Chemical; Dietary Proteins; Glycine; Isoleucine; Leucine; Lysine; Male; Methionine; Proline; Proteins; Serine; Stimulation, Chemical; Threonine; Tyrosine; Valine | 1971 |
Quantitative changes in plasma amino acids induced by oral contraceptives.
Topics: Adult; Alanine; Amino Acids; Contraceptives, Oral; Female; Glutamine; Glycine; Gonadal Steroid Hormones; Humans; Isoleucine; Leucine; Ornithine; Ovulation; Proline; Serine; Tyrosine; Valine | 1971 |
Quantitative amino acids in amniotic fluid and maternal plasma in early and late pregnancy. Preliminary report.
Topics: Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Arginine; Aspartic Acid; Citrulline; Cystine; Female; Gestational Age; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Biosynthesis of riboflavin by Ashbya gossypii. II. The influence of animal proteins on the riboflavin biosynthesis.
Topics: Alanine; Animal Population Groups; Animals; Ascomycota; Autoanalysis; Bone and Bones; Culture Media; Fermentation; Filtration; Gelatin; Glycine; Hydrogen-Ion Concentration; Proline; Proteins; Riboflavin; Skin; Threonine | 1971 |
Amino acid transport by rabbit optic nerve in vitro.
Topics: Alanine; Amino Acids; Animals; Carbon Isotopes; Carrier Proteins; Cyanides; Dinitrophenols; Hydrogen-Ion Concentration; In Vitro Techniques; Iodoacetates; Nerve Tissue Proteins; Optic Nerve; Ouabain; Proline; Rabbits; Sodium | 1971 |
The effect of dietary fluoride on plasma free amino acid concentrations in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Diet; Feeding Behavior; Female; Fluorides; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Rats, Inbred Strains; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Experimental and calculated conformational characteristics of the cyclic decapeptide antamanide.
Topics: 1-Propanol; Alanine; Chemical Phenomena; Chemistry, Physical; Chloroform; Circular Dichroism; Deuterium; Dioxins; Ethanol; Fluorine; Magnetic Resonance Spectroscopy; Mathematics; Methanol; Models, Chemical; Models, Structural; Peptides; Peptides, Cyclic; Phenylalanine; Proline; Protein Conformation; Ultraviolet Rays; Valine | 1971 |
Stimulation of basic amino acid uptake by certain neutral amino acids in isolated intestinal epithelial cells.
Topics: Alanine; Animals; Arginine; Biological Transport; Biological Transport, Active; Carbon Isotopes; Depression, Chemical; Epithelial Cells; Epithelium; Glycine; Histidine; Hydrochloric Acid; Intestinal Mucosa; Intestines; Inulin; Isoleucine; Kinetics; Leucine; Lysine; Male; Mathematics; Methionine; Ornithine; Phenylalanine; Proline; Rats; Rats, Inbred Strains; Serous Membrane; Sodium; Stimulation, Chemical; Tritium; Tryptophan; Valine | 1971 |
Effect of substrate structure on coupling ratio for Na + -dependent transport of amino acids.
Topics: Alanine; Amino Acids; Animals; Asparagine; Biological Transport; Carbon Isotopes; Columbidae; Cysteine; Erythrocytes; Hydroxyproline; Kinetics; Models, Biological; Models, Structural; Potassium; Potassium Isotopes; Proline; Serine; Sodium; Sodium Chloride; Sodium Isotopes; Structure-Activity Relationship; Threonine; Tritium | 1971 |
The effect of vitamin C depletion on the free amino acid content in blood plasma of the guinea pig.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Ascorbic Acid Deficiency; Aspartic Acid; Citrulline; Cysteine; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Time Factors; Tyrosine; Valine | 1971 |
Synthesis of polypeptides and oligopeptides with the repeating sequence L-alanyl-L-prolylglycine.
Topics: Alanine; Benzyl Compounds; Bromine; Chemical Phenomena; Chemistry; Chloroform; Chromatography, Thin Layer; Ethers; Fluoroacetates; Formates; Glycine; Molecular Weight; Nitrophenols; Peptides; Proline; Spectrophotometry; Succinimides; Ultracentrifugation; Ultraviolet Rays | 1971 |
Conformational investigations on the polypeptide and oligopeptides with the repeating sequence L-alanyl-L-prolylglycine.
Topics: 1-Propanol; Alanine; Circular Dichroism; Collagen; Ethanol; Fluorine; Glycine; Glycols; Infrared Rays; Models, Structural; Peptides; Proline; Protein Conformation; Solvents; Spectrophotometry; Ultraviolet Rays; X-Ray Diffraction | 1971 |
Biosynthesis of ergotamine.
Topics: Alanine; Ascomycota; Carbon Isotopes; Chromatography, Gas; Ergolines; Ergotamine; Phenylalanine; Proline | 1971 |
Application of gas-liquid radiochromatography to determination of the optical purity of carbon-14 labeled amino acids.
Topics: Alanine; Amino Acids; Carbon Isotopes; Chlorella; Chromatography, Gas; Cold Temperature; Drug Stability; Leucine; Methods; Proline; Serine; Stereoisomerism; Time Factors; Valine | 1971 |
The metabolism of glutamate, aspartate and alanine in the bovine lens.
Topics: Alanine; Animals; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Cattle; Citric Acid Cycle; Crystallins; Glutamates; Glutathione; In Vitro Techniques; Lactates; Lens, Crystalline; Proline; Pyrrolidinones; Trichloroacetic Acid | 1971 |
[Fractionation of triprotamines from sturgeon milk].
Topics: Alanine; Animals; Cellulose; Chromatography; Chromatography, Ion Exchange; Fishes; Male; Mice; Neoplasms, Experimental; Proline; Protamines; Spectrum Analysis; Spermatozoa; Ultraviolet Rays | 1971 |
Effects of incorporation of trans-4,5-dehydrolysine on collagen biosynthesis and extrusion in embryonic chick tibiae.
Topics: Alanine; Amino Acids; Amino Acyl-tRNA Synthetases; Ammonium Sulfate; Animals; Autoradiography; Carbon Isotopes; Cartilage; Chemical Precipitation; Chick Embryo; Chromatography, Ion Exchange; Collagen; Glycine; Hydroxylysine; Hydroxyproline; Kinetics; Lysine; Proline; Tibia; Tritium | 1971 |
[Antineoplastic effect and chemical structure of protamines of various origin].
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Depression, Chemical; Fishes; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Leukemia, Experimental; Lysine; Methionine; Mice; Proline; Protamines; Sarcoma 37; Serine; Threonine | 1971 |
Extensive charging of transfer ribonucleic acid by bean leaf extracts in vitro.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Aspartic Acid; Calcium Phosphates; Chemical Precipitation; Chromatography; Ethanol; Gels; Hydrogen-Ion Concentration; Lysine; Peptide Biosynthesis; Phenols; Phenylalanine; Plants; Proline; RNA, Transfer; Transfer RNA Aminoacylation | 1971 |
[Behavior of serum amino acids in rats with experimentally produced hyperphenylalaninemia].
Topics: Alanine; Amino Acids; Animals; Disease Models, Animal; Glutamates; Phenylalanine; Proline; Rats; Threonine | 1971 |
The crystal structures of poly(LAla-Gly-Gly-Gly)II and Poly(LAla-Gly-Gly)II.
Topics: Alanine; Crystallins; Glycine; Microscopy, Electron; Models, Structural; Molecular Biology; Molecular Weight; Peptides; Proline; Protein Conformation; Viscosity; X-Ray Diffraction | 1971 |
[Role of triterpenes in the binding of L-amino acids by matricial RNA].
Topics: Alanine; Amino Acid Sequence; Animals; Collagen; Genetic Code; In Vitro Techniques; Molecular Biology; Peptides; Proline; Ribosomes; RNA, Messenger; RNA, Transfer; Terpenes; Wound Healing | 1971 |
Biosynthesis of peptide-type ergot alkaloids. Ergotamine.
Topics: Alanine; Claviceps; Ergonovine; Ergot Alkaloids; Ergotamine; Hydroxy Acids; Lysergic Acid; Phenylalanine; Proline; Pyruvates; Stereoisomerism | 1971 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Serine requirement in leukemic and normal blood cells.
Topics: Alanine; Asparagine; Aspartic Acid; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Culture Media; DNA, Neoplasm; Fibroblasts; Glucose; Glutamates; Glycine; Humans; In Vitro Techniques; Leukemia, Myeloid; Neoplasm Proteins; Proline; RNA, Neoplasm; Serine; Thymidine; Tritium; Uridine | 1969 |
Isoaccepting transfer RNA's of L-M cells in culture and after tumor induction in C3H mice.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cell Line; Chromatography; Connective Tissue; Culture Media; Culture Techniques; Female; Fibrosarcoma; Glycine; Histidine; Isoleucine; Leucine; Ligases; Lysine; Male; Methionine; Mice; Phenylalanine; Proline; RNA, Transfer; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
[Distribution of free amino acids in plasma in patients with a chronic lymphatic and acute leukemia].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Citrulline; Cystine; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Leukemia, Lymphoid; Lysine; Methionine; Ornithine; Phenylalanine; Prednisolone; Proline; Serine; Threonine; Triethylenemelamine; Tyrosine; Valine; Vincristine | 1971 |
Observations on the plasma amino acids of patients with acute leukemia.
Topics: Acute Disease; Alanine; Amino Acids; Asparaginase; Cytarabine; Glucocorticoids; Glutamine; Histidine; Humans; Indicators and Reagents; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Methionine; Methotrexate; Nitrogen; Proline; Threonine; Vincristine | 1971 |
Alpha-aceto-gamma-hydroxybutyramide--a new antimetabolite.
Topics: Alanine; Amides; Animals; Antimetabolites; Escherichia coli; Female; Fetus; Glutamates; Glutamine; Mice; Pregnancy; Pregnancy, Animal; Proline | 1965 |
Imidazolylacetolphosphate:L-glutamate aminotransferase. Composition and substructure.
Topics: Alanine; Ammonia; Arginine; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Electrophoresis; Genes; Glycine; Histidine; Leucine; Methionine; Molecular Biology; Molecular Weight; Peptides; Phenylalanine; Proline; Salmonella typhimurium; Serine; Threonine; Transaminases; Tyrosine; Valine | 1967 |
Thyroid hormones on amino acid and protein metabolism. I. Concentration and composition of free amino acids in blood plasma of the rat.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Circadian Rhythm; Citrulline; Glutamates; Glycine; Hyperthyroidism; Hypothyroidism; Male; Proline; Rats; Stereoisomerism; Thyroid Hormones; Thyroidectomy; Time Factors; Triiodothyronine | 1969 |
Electrochemical studies on the adsorption of amino acids in relation to the compatibility of prosthetic materials and the human body.
Topics: Adsorption; Alanine; Amino Acids; Arginine; Computers; Electrochemistry; Histidine; Hydroxyproline; Lysine; Phenylalanine; Proline; Prostheses and Implants; Surface Tension; Tryptophan; Tyrosine | 1969 |
Mass spectrometry of phenylthiohydantoin (PTH) amino acids.
Topics: Alanine; Amino Acids; Chromatography, Gas; Isoleucine; Leucine; Proline; Spectrum Analysis; Valine | 1969 |
[Chemical and physico-chemical properties of placental protein with antineoplastic effect].
Topics: Alanine; Amino Acids; Ammonia; Antineoplastic Agents; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Electrophoresis; Female; Glutamates; Glycine; Histidine; Humans; Leucine; Lysine; Phenylalanine; Placenta; Proline; Proteins; Serine; Threonine; Tyrosine; Valine | 1969 |
The influence of conditioned media and nonessential amino acid supplementation on the growth of cells in vitro.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cell Division; Cell Line; Chick Embryo; Cricetinae; Culture Media; Glutamates; Glycine; Kidney; L Cells; Proline; Time Factors | 1969 |
Low temperature circular dichroism of poly (glycyl-L-prolyl-L-alanine).
Topics: Alanine; Animals; Chemical Phenomena; Chemistry; Collagen; Glycine; Guinea Pigs; Peptides; Proline; Spectrum Analysis; Temperature; Ultraviolet Rays | 1969 |
Effect of different nitrogen sources on the cellular form of Trigonopsis variabilis.
Topics: Alanine; Culture Media; Hydroxyproline; Methionine; Mitosporic Fungi; Proline | 1969 |
[On the influence of contraceptive pills on serum amino acids in comparison with results typical for sex, menstrual cycle and pregnancy].
Topics: Adult; Alanine; Amino Acids; Citric Acid Cycle; Contraceptives, Oral; Female; Glycine; Humans; Isoleucine; Leucine; Male; Menstruation; Methionine; Pregnancy; Proline; Sex Factors; Threonine; Tyrosine; Urea; Valine | 1969 |
Culture of two-cell rabbit embryos to morulae.
Topics: Alanine; Amino Acids; Animals; Culture Media; Embryo, Mammalian; Embryonic and Fetal Development; Glutamine; Glutathione; In Vitro Techniques; Lactates; Meiosis; Nitrogen; Proline; Pyruvates; Rabbits; Serum Albumin, Bovine | 1970 |
Studies on the catalytic activity of poly-alpha-amino acids. II. Hydrolysis of p-nitrophenyl acetate by an interaction between hydroxyl and carboxyl groups of poly (L-tyr-L-glu), copoly (L-tyr, L-glu, L-ala) or copoly (L-tyr, L-glu, L-pro).
Topics: Acetates; Alanine; Amino Acid Sequence; Amino Acids; Catalysis; Chemical Phenomena; Chemistry; Glutamine; Hydrogen-Ion Concentration; Infrared Rays; Kinetics; Phenylacetates; Polymers; Proline; Spectrum Analysis; Temperature; Tyrosine | 1970 |
The importance of dispensable amino acids for maximal growth in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Body Weight; Citrates; Diet; Glutamates; Glycine; Growth; Male; Nutritional Requirements; Proline; Rats; Serine | 1970 |
Rates of synthesis and degradation of protein in the sea urchin embryo.
Topics: Alanine; Animals; Carbon Isotopes; Echinodermata; Embryo, Nonmammalian; Histidine; Kinetics; Phenylalanine; Proline; Protein Biosynthesis; Threonine; Valine | 1970 |
Derivation of partial sequence of human beta chain messenger RNA from mutation data.
Topics: Alanine; Arginine; Genetic Code; Glycine; Hemoglobins; Humans; Leucine; Mutation; Nucleotides; Proline; RNA, Messenger; Serine; Threonine; Valine | 1970 |
Structural and morphological investigation of poly (gly-ala-pro).
Topics: Alanine; Collagen; Crystallography; Electrons; Glycine; Microscopy, Electron; Peptides; Proline; X-Ray Diffraction | 1970 |
The intestinal absorption of some essential and non-essential amino acids in fed and fasting rats.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Carbon Isotopes; Deficiency Diseases; Fasting; Glycine; Histidine; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Leucine; Male; Methionine; Proline; Rats | 1970 |
Anaerobic glucose stimulation of amino acid transfer in everted small intestine of the rat.
Topics: Alanine; Amino Acids; Animals; Glucose; Intestinal Absorption; Intestine, Small; Methionine; Oxygen; Proline; Rats; Thiourea; Water | 1970 |
Allowed conformations of alanyl preceding prolyl residues.
Topics: Alanine; Amino Acid Sequence; Methods; Peptides; Proline | 1970 |
[Study of chemical composition and antineoplastic effect of protamines isolated from the milt of sturgeon fishes].
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Chromatography, Thin Layer; Depression, Chemical; Electrophoresis; Fishes; Glutamates; Glycine; Histidine; Leucine; Lysine; Male; Methionine; Mice; Molecular Weight; Neoplasms, Experimental; Nucleic Acids; Proline; Protamines; Sarcoma 37; Serine; Spectrum Analysis; Sulfates; Threonine; Ultraviolet Rays | 1970 |
Compoition of fluid secreted by the seminiferous tubules of the rat collected by catheterization and micropuncture technics.
Topics: Alanine; Animals; Aspartic Acid; Catheterization; Chlorides; Glycine; Inositol; Lysine; Male; Methods; Potassium; Proline; Rats; Semen; Sodium; Testis | 1970 |
Droplet countercurrent chromatography.
Topics: Alanine; Amino Acids; Chromatography; Countercurrent Distribution; Cystine; Dinitrophenols; Fluorocarbon Polymers; Ornithine; Proline; Serine; Threonine | 1970 |
The venous plasma free amino acid levels during the first hours of life. II. In a lower socio-economic group of a refugee area in Karachi, West Pakistan, with special reference to the "small for dates" syndrome.
Topics: Alanine; Amino Acids; Birth Weight; Gestational Age; Glycine; Growth; Growth Disorders; Humans; Infant, Newborn; Leucine; Pakistan; Proline; Protein Deficiency; Socioeconomic Factors; Time Factors; Valine; Veins; White People | 1970 |
Gas-liquid chromatography and mass spectrometry of deuterium-containing amino acids as their trimethylsilyl derivatives.
Topics: Alanine; Amino Acids; Asparagine; Chromatography, Gas; Deuterium; Glycine; Leucine; Methionine; Proline; Silicon; Spectrum Analysis; Tyrosine; Valine | 1970 |
N-substituted amino acids in serum of patients with chronic renal insufficiency.
Topics: Alanine; Amino Acids; Aspartic Acid; Cystine; Glutamates; Glycine; Humans; Kidney Failure, Chronic; Phenylalanine; Proline | 1970 |
Changes in the concentration of specific amino acids in the serum of experimentally malnourished pigs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Dietary Proteins; Female; Gluconeogenesis; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Protein Deficiency; Serine; Swine; Threonine; Tyrosine; Valine | 1970 |
Metabolism of amino acids in incubated slices of mouse brain.
Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Brain; Carbon Isotopes; Centrifugation; Cerebellum; Cerebral Cortex; Chromatography, Paper; Glucose; Histidine; In Vitro Techniques; Leucine; Lysine; Medulla Oblongata; Mesencephalon; Mice; Oxygen Consumption; Phenylalanine; Pons; Proline; Valine | 1970 |
Determination of pico-mole quantities of gamma-amino-butyric acid (GABA) and serotonin.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoradiography; Brain Chemistry; Carbon Isotopes; Cerebellum; Chromatography; Cysteine; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methods; Microchemistry; Phenylalanine; Proline; Radionuclide Imaging; Rats; Serine; Serotonin; Threonine; Tyrosine; Valine | 1970 |
Amino acid permeability of pea chloroplasts as measured by osmotically determined reflection coefficients.
Topics: Alanine; Amides; Amino Acids; Cell Membrane Permeability; Chloroplasts; Glycine; Imines; Isoleucine; Leucine; Methionine; Osmolar Concentration; Osmotic Pressure; Phenylalanine; Plants; Proline; Serine; Sucrose; Threonine; Valine | 1970 |
Quantitative cation-exchange chromatographic analysis of free amino acids in human amniotic fluid collected during early pregnancy.
Topics: Alanine; Amino Acids; Amino Alcohols; Aminobutyrates; Amniotic Fluid; Autoanalysis; Chromatography, Ion Exchange; Female; Fetus; Glutamates; Glutamine; Glycine; Humans; Lysine; Pregnancy; Proline; Threonine; Time Factors; Valine | 1970 |
Indications of spatial relations among structures recognizing amino acids and Na+ at a transport receptor site.
Topics: Alanine; Amino Acids; Animals; Arginine; Binding Sites; Biological Transport; Canavanine; Columbidae; Erythrocytes; Guanidines; Lysine; Models, Biological; Models, Structural; Ornithine; Proline; Propionates; Rabbits; Reticulocytes; Serine; Sodium; Threonine | 1970 |
The nutritive effect in man of non-essential amino acids infused intravenously (together with the essential ones). I. Individual non-essential amino acids.
Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Creatinine; Female; Glutamates; Glycine; Histidine; Humans; Injections, Intravenous; Middle Aged; Nausea; Proline; Urea | 1970 |
Influence of pregnancy and-or exercise on intestinal transport of amino acids in rats.
Topics: Adrenal Glands; Alanine; Amino Acids; Animals; Body Weight; Carbon Isotopes; Digestive System Physiological Phenomena; Female; Intestinal Absorption; Lysine; Organ Size; Physical Exertion; Pregnancy; Pregnancy, Animal; Proline; Rats | 1970 |
Proline transport by rabbit ciliary body-iris in vitro.
Topics: Alanine; Amino Acids; Animals; Arginine; Biological Transport; Carbon Isotopes; Centrifugation; Choroid Plexus; Chromatography; Ciliary Body; Diffusion; In Vitro Techniques; Iris; Optic Nerve; Proline; Rabbits | 1970 |
The effect on the nitrogen balance of the ratio essential-non-essential amino acids in intravenously infused solutions.
Topics: Adult; Alanine; Amino Acids; Arginine; Aspartic Acid; Blood Urea Nitrogen; Female; Glycine; Histidine; Humans; Infusions, Parenteral; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Proline; Threonine; Tryptophan; Valine | 1970 |
Neutral amino acid transport in Pseudomonas fluorescens.
Topics: Alanine; Alanine Transaminase; Amino Acids; Biological Transport, Active; Carbon Isotopes; Cell Membrane; Chromatography, Paper; Cyanides; Depression, Chemical; Dinitrophenols; Genetics, Microbial; Membrane Transport Proteins; Mutation; Proline; Pseudomonas; Stereoisomerism | 1970 |
[Effect of amino acids on the growth of Streptococcus lactis and biosynthesis of nisin].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Depression, Chemical; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Stimulation, Chemical; Streptococcus; Threonine; Tryptophan; Valine | 1970 |
The conformational energy map of an alanyl residue preceding proline: a quantum-mechanical approach.
Topics: Alanine; Albumins; Carboxypeptidases; Chemical Phenomena; Chemistry; Chemistry, Physical; Chymotrypsin; Hemoglobins; Muramidase; Muscle Proteins; Peptides; Proline; Pyrrolidines; Quantum Theory; Ribonucleases; X-Ray Diffraction | 1970 |
The isolation and properties of a beta-alanine permeaseless mutant of Pseudomonas fluorescens.
Topics: Alanine; Amino Acids; Biological Transport, Active; Carbon Isotopes; Cell Membrane; Diffusion; Energy Transfer; Membrane Transport Modulators; Membrane Transport Proteins; Mutation; Proline; Propionates; Pseudomonas; Transaminases | 1970 |
Lysine uptake in cultured Trypanosoma cruzi: interactions of competitive inhibitors.
Topics: Alanine; Animals; Biological Transport; Cysteine; Glycine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Trypanosoma; Tyrosine; Valine | 1970 |
Carboxyl-terminal residues of fibrinogen and fibrin.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Autoanalysis; Carboxypeptidases; Cattle; Chemical Phenomena; Chemistry; Fibrin; Fibrinogen; Hydrazines; Pancreas; Peptides; Proline; Protein Denaturation; Ribonucleases; Time Factors; Tritium; Valine | 1970 |
A distinct, Na+-dependent glycine transport system in avian small intestine.
Topics: Alanine; Amino Acids; Anaerobiosis; Animals; Binding Sites; Biological Transport; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Chickens; Female; Glutamates; Glycine; Intestinal Absorption; Intestine, Small; Kinetics; Lysine; Methionine; Potassium Chloride; Proline; Sodium; Temperature | 1970 |
Nitrogen and amino acids in the feces of young pigs receiving a protein-free diet and diets containing graded levels of soybean oil meal or casein.
Topics: Alanine; Amino Acids; Animals; Caseins; Chromatography, Gas; Dietary Proteins; Feces; Glutamates; Glycine max; Isoleucine; Leucine; Male; Nitrogen; Oils; Proline; Swine | 1970 |
Incorporation of cis-hydroxyproline into protocollagen and collagen. Collagen containing cis-hydroxyproline in place of proline and trans-hydroxyproline is not extruded at a normal rate.
Topics: Alanine; Animals; Autoradiography; Carbon Isotopes; Cartilage; Chick Embryo; Chromatography, Gel; Collagen; Hydroxyproline; Lysine; Proline; Protein Biosynthesis; Puromycin; Stereoisomerism; Tibia; Tritium | 1971 |
Patterns of neutral amino acid uptake along rat small intestine.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Betaine; Biological Transport, Active; Carbon Isotopes; Glycine; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Leucine; Male; Methionine; Proline; Rats; Stimulation, Chemical | 1971 |
Nutrient media for plant-parasitic nematodes. II. Amino acid requirements of Aphelenchoides sp.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Fungi; Germ-Free Life; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Nematoda; Nutritional Requirements; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Multiple neutral amino acid transport systems in chicken small intestine: evidence for a separate proline transfer agency.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Chickens; Depression, Chemical; In Vitro Techniques; Intestine, Small; Kinetics; Proline; Sarcosine; Taurine | 1971 |
Amino acid metabolism in the isolated perfused rat liver.
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Chromatography; Glutamates; Glycine; In Vitro Techniques; Liver; Lysine; Male; Methionine; Nitrogen Isotopes; Perfusion; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Urea | 1971 |
Cyanogen bromide fragments of human serum albumin.
Topics: Acetamides; Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cyanides; Cysteine; Electrophoresis; Formates; Guanidines; Humans; Hydrogen-Ion Concentration; Iodoacetates; Leucine; Methods; Naphthalenes; Oxidation-Reduction; Peptides; Phenylalanine; Proline; Quaternary Ammonium Compounds; Serum Albumin; Sulfates; Sulfhydryl Reagents; Sulfonic Acids; Tetroses; Urea | 1971 |
Development of ordered structures in sequential copolypeptides containing L-proline and -hydroxy-L-proline.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Chemical Phenomena; Chemistry; Circular Dichroism; Glycine; Glycols; Hydroxyproline; Molecular Biology; Molecular Weight; Peptides; Proline; Temperature; Ultraviolet Rays; Viscosity; Water | 1971 |
Unperturbed dimensions of sequential copolypeptides containing glycine, L-alanine, L-proline, and -hydroxy-L-proline.
Topics: Alanine; Chemical Phenomena; Chemistry; Computers; Glycine; Hydroxyproline; Molecular Weight; Peptides; Proline; Ultracentrifugation; Viscosity | 1971 |
Essential amino acids in the culture of Leishmania tarentolae.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Glucose; Glutamates; Glycine; Histidine; Leishmania; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Comparative studies on the primary structure of soluble and mitochondrial glutamic oxaloacetic transaminase isozymes. II. Amino acid sequence of the amino terminal fragments.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aminobutyrates; Animals; Aspartate Aminotransferases; Chemical Phenomena; Chemistry; Chromatography, Paper; Chymotrypsin; Cyanides; Endopeptidases; Glutamates; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Hydroxybutyrates; Isoenzymes; Mitochondria, Muscle; Myocardium; Peptides; Phenylalanine; Proline; Serine; Solubility; Swine; Thiocyanates; Tryptophan; Valine | 1971 |
The relationship of adrenal glucocorticoids to transaminase activity and gluconeogenesis in the intact rat.
Topics: Adrenalectomy; Alanine; Animals; Aspartate Aminotransferases; Aspartic Acid; Biological Transport; Blood Glucose; Carbon Isotopes; Cell Membrane Permeability; Chromatography, Ion Exchange; Extracellular Space; Fasting; Glucocorticoids; Gluconeogenesis; Glucose; Glutamates; Glycine; Isoleucine; Kinetics; Liver; Methionine; Phenylalanine; Proline; Rats; Transaminases; Tritium; Tyrosine; Valine; Water | 1971 |
Transfer of alanine isomers by rat small intestine.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Galactose; Glucose; Hexoses; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Isomerism; Male; Mannitol; Methionine; Proline; Rats; Sarcosine | 1971 |
[Free amino acids and other ninhydrin-positive substances in the normal horny layer and in psoriasis scales].
Topics: Alanine; Amino Acids; Ammonia; Asparagine; Chromatography; Citrulline; Cysteine; Glycine; Histidine; Humans; Imidazoles; Phenylalanine; Proline; Psoriasis; Serine; Skin; Taurine; Threonine; Urea | 1967 |
[Chemistry of the antibiotic A-128 (neotelomycin)--qualitative and quantitative amino acid composition].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Aspartic Acid; Chemistry Techniques, Analytical; Chromatography, Paper; Electrophoresis; Glycine; Proline; Serine; Threonine; Tryptophan | 1967 |
[Biosphere products of Sinapis alba. I. Rhizosphere products].
Topics: Alanine; Amino Acids; Aminobutyrates; Arabinose; Arginine; Aspartic Acid; Citrates; Cysteine; Glucose; Glutamates; Glycine; Hexoses; Histidine; Keto Acids; Leucine; Mannose; Mustard Plant; Oxalates; Pentoses; Plants, Medicinal; Proline; Ribose; Threonine; Valine; Xylose | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Effect of pyruvate and other substrates on urea synthesis in rat liver slices.
Topics: Acetates; Alanine; Animals; Caprylates; Citrulline; Depression, Chemical; Electrophoresis; Fructose; Glucose; Lactates; Liver; Male; Ornithine; Paper; Proline; Pyruvates; Rats; Succinates; Urea | 1968 |
Two trypsin inhibitors from porcine pancreatic juice.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Enzyme Precursors; Glutamates; Glutamine; Guanidines; In Vitro Techniques; Kallikreins; Molecular Weight; Pancreatic Juice; Proline; Serine; Species Specificity; Spectrum Analysis; Swine; Threonine; Trypsin; Trypsin Inhibitors; Ultracentrifugation; Ultraviolet Rays | 1968 |
Dipeptidyl arylamidase II of the pituitary. Properties of lysylalanyl-beta-naphthylamide hydrolysis: inhibition by cations, distribution in tissues, and subcellular localization.
Topics: Acid Phosphatase; Alanine; Animals; Arginine; Cattle; Centrifugation, Density Gradient; Chromatography, Paper; Cytoplasm; Dipeptides; Endopeptidases; Glycine; Hydrogen-Ion Concentration; Kidney; Kinetics; Leucine; Lithium; Lysine; Lysosomes; Methionine; Naphthalenes; Nucleosides; Pituitary Gland; Potassium; Proline; Protease Inhibitors; Puromycin; Rats; Serine; Sodium; Spleen; Thyroid Gland; Tromethamine; Tyrosine | 1968 |
Amino acid transport in kidney. Heterogeneity of alpha-aminoisobutyric uptake.
Topics: Alanine; Amides; Aminoisobutyric Acids; Animals; Biological Transport; Carbon Isotopes; Choline; Cyanides; Fluorides; Glycine; Kidney; Kinetics; Leucine; Lysine; Ouabain; Proline; Rats; Sodium; Temperature | 1968 |
Breakdown of protein: cleavage of peptides of the X-pro-Y type by kidney peptidases.
Topics: Alanine; Animals; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Disc; Glycine; Hydrogen-Ion Concentration; Hydroxyproline; Kidney; Manganese; Microsomes; Peptide Hydrolases; Proline; Swine | 1968 |
Characterization of the transport of neutral amino acids by the calf lens.
Topics: Alanine; Amino Acids; Animals; Binding Sites; Biological Transport; Buffers; Carbon Isotopes; Cattle; Cell Membrane Permeability; Glycine; Lens, Crystalline; Leucine; Methionine; Phenylalanine; Proline; Protein Biosynthesis; Rabbits; Sarcosine; Tetraethylammonium Compounds; Tritium | 1968 |
Amino acid constituents of stendomycin.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Antifungal Agents; Arginine; Chromatography, Ion Exchange; Chromatography, Thin Layer; Glycine; Isoleucine; Magnetic Resonance Spectroscopy; Peptides; Proline; Spectrum Analysis; Threonine; Valine | 1968 |
A study of 2,4,6-trinitrobenzenesulfonic acid for automated amino acid chromatography.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Autoanalysis; Chromatography; Cystine; Glycine; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Isoleucine; Leucine; Lysine; Methionine; Methods; Nitrobenzenes; Phenylalanine; Proline; Serine; Spectrophotometry; Sulfonic Acids; Temperature; Threonine; Tryptophan; Tyrosine; Urea; Valine | 1968 |
Primary structure of insoluble tendon collagen. 3. Analysis of products of tryptic digestion of native collagen.
Topics: Achilles Tendon; Alanine; Aldehydes; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cysteine; Electrophoresis; Glutamine; Glycine; Hexosamines; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Proline; Serine; Sulfur; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Trace metal requirements for malformin biosynthesis.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Aspergillus; Chromium; Cobalt; Copper; Cysteine; Glutamine; Glycine; Histidine; Iron; Isoleucine; Leucine; Lysine; Manganese; Metals; Molybdenum; Peptide Biosynthesis; Phenylalanine; Plant Growth Regulators; Proline; Serine; Trace Elements; Tryptophan; Tyrosine; Valine; Zinc | 1968 |
The venom of the honeybee (Apis mellifera): free amino acids and peptides.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Autoanalysis; Bees; Chromatography, Gel; Chromatography, Paper; Chromatography, Thin Layer; Glutamine; Glycine; Histamine; Peptides; Proline; Solubility; Venoms | 1968 |
Calf and pea histone IV. I. Amino acid compositions and the identical COOH-terminal 19-residue sequence.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Evolution; Bromine; Cattle; Chromatography, Gel; Chymotrypsin; Cyanides; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Plants; Proline; Serine; Threonine; Trypsin; Tyrosine; Valine | 1968 |
[Comparative study of the initial structure of muscle aldolase in normal and fasted rabbits].
Topics: Alanine; Amino Acids; Animals; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Crystallization; Electrophoresis; Fasting; Fructose-Bisphosphate Aldolase; Muscles; Peptides; Proline; Rabbits; Sulfhydryl Compounds; Urea | 1968 |
Two procedures for accelerated separation of amino acids by column chromatography.
Topics: Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Buffers; Chromatography, Ion Exchange; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Methods; Phenylalanine; Proline; Serine; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Gas chromatographic behavior of trimethylsilylated phenylthiohydantoin amino acids.
Topics: Alanine; Amino Acids; Arginine; Chromatography, Gas; Glutamates; Glutamine; Hydantoins; Leucine; Methionine; Methods; Methylation; Phenylalanine; Proline; Serine; Silicon; Spectrum Analysis; Tyrosine | 1968 |
States of amino acid residues in proteins. XVI. Naphthoquinones with two sulfonic groups as a reagent for discrimation of amino groups in proteins.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chymotrypsin; Colorimetry; Freezing; Glycine; Histidine; Hydrogen-Ion Concentration; Imidazoles; Indicators and Reagents; Insulin; Lysine; Muramidase; Naphthoquinones; Proline; Proteins; Ribonucleases; Serine; Spectrophotometry; Sulfonic Acids; Tryptophan; Tyrosine | 1968 |
Fractionation of histones from calf thymus and posterior silkglands by countercurrent distribution.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Bombyx; Cattle; Electrophoresis; Histones; Lysine; Methods; Phenylalanine; Proline; Thymus Gland; Trichloroacetic Acid; Urea | 1968 |
Transferrin DChi: the amino acid substitution.
Topics: Alanine; Amino Acid Sequence; Arginine; Aspartic Acid; Glutamates; Histidine; Humans; Lysine; Peptides; Proline; Serine; Transferrin; Trypsin; Valine | 1968 |
Influence of protein digestion on plasma amino acid levels in sheep.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Caseins; Digestion; Glutamates; Glycine; Histidine; Intestinal Mucosa; Isoleucine; Leucine; Lysine; Male; Phenylalanine; Proline; Sheep; Tyrosine; Valine | 1968 |
Fermentation of ornithine by Clostridium sticklandii.
Topics: Alanine; Carbon Isotopes; Clostridium; Ornithine; Oxidation-Reduction; Proline; Pyruvates | 1968 |
Glycoprotein structure: the carbohydrate of bovine corneal collagen.
Topics: Alanine; Animals; Carbohydrates; Cattle; Chromatography, Gas; Collagen; Cornea; Galactose; Glucose; Glycine; Glycoproteins; Hexosamines; Hydroxyproline; Mannose; Neuraminic Acids; Proline; Xylose | 1968 |
Studies on membrane transport. 3. Further characterization of amino acid systems in Hymenolepis diminuta (Cestoda).
Topics: Absorption; Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Biological Transport; Carbon Isotopes; Cell Membrane; Cestoda; Cyclopentanes; Kinetics; Leucine; Lysine; Phenylalanine; Proline; Rats; Valine | 1968 |
Conformational energies and configurational statistics of copolypeptides containing L-proline.
Topics: Alanine; Glycine; Macromolecular Substances; Mathematics; Models, Chemical; Peptides; Proline | 1968 |
Oligopeptides with the sequences ala-pro-gly and gly-pro-gly as substrates or inhibitors for protocollagen proline hydroxylase.
Topics: Alanine; Amino Acid Sequence; Chemical Phenomena; Chemistry; Collagen; Glycine; Hydroxyproline; Mixed Function Oxygenases; Peptides; Proline | 1969 |
Radiation-induced hydrogen isotope exchange in solutions of polyamino acids.
Topics: Alanine; Cobalt Isotopes; Free Radicals; Glutamates; Nitrates; Peptides; Proline; Radiation Effects; Radiochemistry; Tritium | 1969 |
Effect of glucagon on concentration of several free amino acids in plasma.
Topics: Alanine; Amino Acids; Arginine; Citrulline; Cystine; Depression, Chemical; Fasting; Female; Glucagon; Glycine; Histidine; Humans; Leucine; Liver; Lysine; Male; Methionine; Nitrogen; Phenylalanine; Progesterone; Proline; Serine; Threonine; Tyrosine; Valine | 1969 |
Amino acid composition of gluten fractions.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chemical Precipitation; Dialysis; Glutamates; Glutens; Glycine; Hydrogen-Ion Concentration; Lysine; Magnesium Sulfate; Papain; Proline; Salicylates; Sulfates; Sulfites; Threonine; Tryptophan | 1969 |
Chemical characterization of a non-covalently linked peptide from plakalbumin.
Topics: Alanine; Albumins; Amino Acid Sequence; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry; Hydrazines; Methods; Ovalbumin; Peptides; Proline; Serine; Urea | 1969 |
Transport of alanine isomers by rat small intestine in vitro.
Topics: Alanine; Animals; Biological Transport, Active; Galactose; Glucose; In Vitro Techniques; Intestine, Small; Methionine; Proline; Rats; Sarcosine; Stereoisomerism | 1969 |
Pyrrolidonecarboxylyl peptidase: studies on the specificity of the enzyme.
Topics: Alanine; Chemical Phenomena; Chemistry; Dipeptides; Isoleucine; Leucine; Peptide Hydrolases; Phenylalanine; Proline; Pseudomonas; Pyrrolidinones; Stereoisomerism; Tyrosine; Valine | 1969 |
Amino acid feeding studies: effects of various nonessential nitrogen sources and of added water.
Topics: Alanine; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Body Weight; Diet; Glutamates; Glycine; Male; Nitrogen; Proline; Rats; Serine | 1969 |
The effect of monovalent cations on the incorporation of various amino acids in protein synthesis by isolated rat spleen nuclei.
Topics: Alanine; Amino Acids; Animals; Carbon Isotopes; Cell Nucleus; Glycine; Leucine; Lithium; Methionine; Phenylalanine; Potassium; Proline; Protein Biosynthesis; Rats; Rubidium; Sodium; Spleen; Stimulation, Chemical; Threonine | 1969 |
Amino acid transport in adult diaphyseal bone: contrast with amino acid transport mechanisms in fetal membranous bone.
Topics: Age Factors; Alanine; Amides; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Bone and Bones; Carbon Isotopes; Cyanides; Depression, Chemical; Female; Fluorides; Hydroxyproline; Imines; Membranes; Methods; Pregnancy; Proline; Rats; Serine; Sodium; Sucrose; Tibia; Time Factors; Tritium | 1969 |
Proline metabolism in Leishmania tarentolae.
Topics: Alanine; Amino Acid Oxidoreductases; Amino Acids; Animals; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Chromatography, Thin Layer; Citric Acid Cycle; Culture Media; Glucose; Glutamates; Hydroxyproline; Leishmania; Malate Dehydrogenase; Methionine; Oxygen Consumption; Proline; Spectrophotometry | 1969 |
Direct synthesis of p-methoxybenzyl carbazate and p-methoxybenzyloxycarbonylamino acids using p-methoxybenzyl chloroformate as reagent.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chloroform; Glutamates; Glutamine; Glycine; Hydrazines; Indicators and Reagents; Isoleucine; Leucine; Phenylalanine; Proline; Sodium Hydroxide; Stereoisomerism; Threonine; Tyrosine; Valine | 1969 |
Statistical analysis of the distribution of amino acid residues among helical and non-helical regions in globular proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Chymotrypsin; Hemoglobins; Leucine; Muramidase; Myoglobin; Papain; Proline; Proteins; Ribonucleases; Statistics as Topic | 1969 |
Characterization of sea urchin sperm chromatin and its basic proteins.
Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Chromosomes; DNA; Echinodermata; Electrophoresis, Disc; Histones; Hydrogen-Ion Concentration; Lysine; Male; Nucleic Acid Denaturation; Osmolar Concentration; Proline; Proteins; RNA; Spectrophotometry; Spermatozoa; Templates, Genetic | 1969 |
Histones in early embryogenesis.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Echinodermata; Electrophoresis; Embryo, Nonmammalian; Fishes; Gels; Genetic Code; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
Comparison of the efficiency of proteins contained in lucerne hay and soya-bean meal for sheep.
Topics: Alanine; Amino Acids; Ammonia; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Fatty Acids; Female; Glycine max; Male; Nitrogen; Plant Proteins; Poaceae; Proline; Protein Biosynthesis; Rumen; Sheep; Urea; Valerates; Valine | 1969 |
Structural requirements for binding of bradykinin to antibody. 3. The effect of carrier on antibody specificity.
Topics: Alanine; Amino Acid Sequence; Animals; Antibodies; Antigen-Antibody Reactions; Binding Sites; Bradykinin; Carbon Isotopes; Chemical Phenomena; Chemistry; Depression, Chemical; Glycine; Humans; Immune Sera; Kinins; Lysine; Ovalbumin; Peptides; Proline; Rabbits; Radioimmunoassay; Sheep | 1969 |
Stereochemical specificity of neutral amino acid transfer systems in rat small intestine.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Carbon Isotopes; Cysteine; Hydroxyproline; Ileum; Intestine, Small; Jejunum; Leucine; Methionine; Pipecolic Acids; Proline; Rats; Sarcosine; Serine; Stereoisomerism | 1969 |
Preferential binding of amino acids to isolated mucosal brush borders from hamster jejunum.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Benzoates; Binding Sites; Biological Transport, Active; Carbon Isotopes; Cricetinae; Epithelium; Glucosamine; Glucose; Histidine; Intestinal Mucosa; Jejunum; Potassium Chloride; Proline; Sodium Chloride; Tritium | 1969 |
End product control of amino acid synthesis by cultured human cells.
Topics: Alanine; Arginine; Culture Techniques; Enzyme Repression; Glucose; Glutamine; Glycine; Humans; Methionine; Ornithine; Proline; Serine | 1965 |
[RNA isolated from turnip yellow mosaic virus; acceptor of amino acids in the presence of bacterial enzymes].
Topics: Alanine; Alcaligenes; Amino Acids; Arginine; In Vitro Techniques; Isoleucine; Leucine; Nucleotides; Phenylalanine; Plant Viruses; Proline; RNA, Viral; Serine; Ultracentrifugation; Valine | 1965 |
Optical resolution of D,L amino acids by gas chromatography and mass spectrometry.
Topics: Alanine; Amino Acids; Aminobutyrates; Chemical Phenomena; Chemistry, Physical; Chromatography, Gas; Glycine; Leucine; Proline; Spectrum Analysis; Thiazoles | 1965 |
Stimulation of the binding of aminoacyl-sRNA to ribosomes by tubercidin (7-deazaadenosine) and N 6-dimethyladenosine containing trinucleoside diphosphate analogs.
Topics: Alanine; Anti-Bacterial Agents; Glutamates; Glycine; In Vitro Techniques; Lysine; Nucleotides; Proline; Ribosomes; RNA, Transfer; Serine; Threonine | 1965 |
Amino acids in seven species of cestodes.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cestoda; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Nitrogen; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Effect of amino acids on sugar absorption.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Cricetinae; Glutamates; Hexoses; Histidine; Intestinal Absorption; Ornithine; Proline; Valine | 1966 |
Amino acid compostion of walls from single and filamentous cells of Clostridium acidiurici.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacterial Proteins; Cell Wall; Chromatography; Clostridium; Glutamates; Glycine; In Vitro Techniques; Isomerases; Leucine; Lysine; Methionine; Oxidoreductases; Phenylalanine; Proline; Serine; Valine | 1966 |
Formation of the L-proline pool of the cestode, Hymenolepis diminuta.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Carbon Isotopes; Cestoda; Glucose; Hydroxyproline; Lysine; Proline | 1966 |
Polyamide layer chromatography of DNP-amino acids.
Topics: Alanine; Amides; Arginine; Aspartic Acid; Chromatography; Dinitrophenols; Glutamates; Glycine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
Development of structure and function in the mammalian yolk sac. 3. The development of amino acid transport by rabbit yolk sac.
Topics: Alanine; Amino Acids; Animals; Betaine; Biological Transport; Carbon Isotopes; Female; Fetus; Glycine; Glycosides; In Vitro Techniques; Inulin; Isoleucine; Lysine; Maternal-Fetal Exchange; Methionine; Phenylalanine; Placenta; Pregnancy; Pregnancy, Animal; Proline; Quaternary Ammonium Compounds; Rabbits; Valine | 1966 |
The metabolism of L-glutamate and L-5-carboxy-pyrrolidone by mouse cells (NCTC clone 929) under conditions of defined nutrition.
Topics: Alanine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Paper; Culture Media; Glutamates; Ketoglutaric Acids; L Cells; Mice; Proline; Pyrrolidinones; Transaminases | 1966 |
Water relations of Salmonella oranienburg; stimulation of respiration by amino acids.
Topics: Alanine; Asparagine; Aspartic Acid; Carbon Isotopes; Culture Media; Cysteine; Glucose; Glutamine; Glycine; Methionine; Oxygen Consumption; Proline; Salmonella; Serine; Threonine; Water | 1966 |
Gas chromatographic separation of DNP amino acids and its application to the analysis of serum amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Cholesterol; Chromatography, Gas; Glutamates; Glycine; Hydroxyproline; Indicators and Reagents; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Valine | 1966 |
Nuclear histones and early embryogenesis of the chick.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Cell Division; Cell Nucleus; Chick Embryo; Electrophoresis; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
[On the structure of protamine. VII. On the effect of the age of the fishes on the composition of their protamine].
Topics: Age Factors; Alanine; Amino Acids; Animals; Arginine; Fishes; Glutamates; Proline; Protamines; Serine; Threonine; Tyrosine; Valine | 1966 |
Free amino acids of human foetal and adult liver.
Topics: Adult; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Cystine; Female; Fetus; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1966 |
Reassessment of some amino acid requirements of larvae of Oryzaephilus surinamensis (L.) (coleoptera: silvanidae).
Topics: Alanine; Amino Acids; Animals; Arginine; Coleoptera; Cystine; Lysine; Methionine; Proline; RNA | 1967 |
Free amino acids in gamma-irradiated carrots.
Topics: Acetates; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Carbon Isotopes; Glutamates; Leucine; Methionine; Plants, Edible; Proline; Radiation Effects; Serine; Threonine; Tyrosine | 1967 |
Rate constants of hydrated electron reactions with peptides and proteins.
Topics: Alanine; Albumins; Asparagine; Electrons; Gelatin; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Molecular Weight; Muramidase; Peptides; Phenylalanine; Proline; Proteins; Ribonucleases; Tryptophan; Tyrosine; Valine | 1967 |
Further studies of amino acid transport by embryonic chick bone.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Bone and Bones; Chick Embryo; Dactinomycin; Ethylmaleimide; Glycine; In Vitro Techniques; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Comparison of the carbohydrate and amino acid composition of bovine, ovine and human luteinizing hormone.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cattle; Galactose; Glucosamine; Glutamates; Hexosamines; Hexoses; Humans; In Vitro Techniques; Luteinizing Hormone; Lysine; Mannose; Neuraminic Acids; Proline; Serine; Sheep; Threonine; Valine | 1967 |
On the formation of amino acids by gamma-ray-induced carboxylation of amines in aqueous solutions.
Topics: Alanine; Amines; Amino Acids; Aminobutyrates; Aspartic Acid; Carbon Dioxide; Chemistry, Organic; Cobalt Isotopes; Glutamates; Glycine; Hydrogen-Ion Concentration; Leucine; Organic Chemistry Phenomena; Proline; Radiation Effects; Valine; Water | 1967 |
The metabolism of triglycerides by spores of Penicillium roqueforti.
Topics: Alanine; Azides; Chloramphenicol; Dinitrophenols; Enzymes; Esterases; Glycerides; Isoflurophate; Ketones; Oxygen Consumption; Penicillium; Phosphates; Proline; Serine; Spores; Triglycerides | 1967 |
Low-molecular-weight compounds in Macrocystis pyrifera, a marine alga.
Topics: Alanine; Alcohols; Amino Acids; Aspartic Acid; Chromatography; Eukaryota; Glutamates; Glycerol; Leucine; Proline; Succinates; Taurine; Valine | 1967 |
Polymers of tripeptides as collagen models. 3. Structural relationship between two forms of poly(L-prolyl-L-alanyl-glycine).
Topics: Alanine; Chemical Phenomena; Chemistry; Collagen; Glycine; Models, Theoretical; Peptides; Polymers; Proline; X-Ray Diffraction | 1967 |
The recovery of amino acids from acid hydrolysates of whole urine from patients with thermal burns.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Burns; Creatine; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1967 |
The influence of medium composition on the growth and swarming of Proteus.
Topics: Alanine; Asparagine; Aspartic Acid; Culture Media; Glutamates; Glutamine; Proline; Proteus; Serine | 1967 |
The utilization of D-amino acids by yeasts.
Topics: Alanine; Amino Acids; Candida; Cryptococcus; Glutamates; Proline; Saccharomyces; Serine; Sewage; Soil Microbiology; Water Microbiology; Yeasts | 1967 |
Electron microscopic and biochemical characterization of collagen in blattarian insects.
Topics: Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Collagen; Connective Tissue Cells; Cysteine; Cystine; Female; Glutamates; Glycine; Histidine; Histocytochemistry; Hydroxyproline; Insecta; Isoleucine; Leucine; Lysine; Male; Methionine; Microscopy, Electron; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1967 |
Rapid short-column chromatography of amino acids. A method for blood and urine specimens in the diagnosis and treatment of metabolic disease.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Aminobutyrates; Autoanalysis; Buffers; Chromatography, Ion Exchange; Citrates; Cysteine; Cystine; Glutamates; Glutamine; Glycine; Humans; Hydrogen-Ion Concentration; Hydroxyproline; Isoleucine; Phenylalanine; Proline; Sarcosine; Serine; Threonine; Tyrosine; Valine | 1967 |
Gluconeogenesis from amino acids in neonatal rat liver.
Topics: Alanine; Alanine Transaminase; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartate Aminotransferases; Aspartic Acid; Gluconeogenesis; Glutamates; Glycine; Histidine; In Vitro Techniques; Leucine; Liver; Liver Glycogen; Phenylalanine; Proline; Rats; Serine; Spectrophotometry; Threonine; Tyrosine; Valine | 1967 |
Requirements for growth of Streptococcus agalactiae in a chemically defined medium.
Topics: Alanine; Ascorbic Acid; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Proline; Serine; Streptococcus; Thioglycolates | 1967 |
The active transport of selected amino acids across the gut of the chiton (Cryptochiton stelleri). 1. Mapping determinations and effects of anaerobic conditions.
Topics: Alanine; Aminoisobutyric Acids; Animals; Autoradiography; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Glutamates; Glycine; Intestinal Mucosa; Lysine; Mollusca; Proline | 1967 |
Ergot alkaloids. I. Biosynthesis of the peptide side chain.
Topics: Alanine; Ascomycota; Carbon Isotopes; Ergot Alkaloids; Ergotamine; Leucine; Methionine; Peptide Biosynthesis; Phenylalanine; Proline; Pyruvates; Valine | 1967 |
The effect of progesterone on the concentration of plasma amino acids in man.
Topics: Acromegaly; Alanine; Amino Acids; Arginine; Citrulline; Cystine; Fasting; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Progesterone; Proline; Proteins; Threonine; Tyrosine; Valine | 1967 |
The biosynthesis of proline by Tetrahymena pyriformis.
Topics: Acids; Alanine; Arginine; Carbon Isotopes; Citrulline; Glutamates; Hot Temperature; Hydrogen-Ion Concentration; Hydrolases; Ketoglutaric Acids; Kinetics; Metals; Ornithine; Oxidoreductases; Proline; Protein Denaturation; Pyrroles; Tetrahymena; Transaminases; Ureohydrolases; Valine | 1967 |
The conversion of glutamate to alanine in the tsetse fly (Glossina morsitans).
Topics: Alanine; Animals; Arginine; Carbon Isotopes; Chromatography, Paper; Glutamates; Male; Oxaloacetates; Physical Exertion; Proline; Tsetse Flies | 1967 |
Effect of amino acids on zinc-65 incorporation by Ehrlich ascites tumor cells in vitro.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Female; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Lysine; Methionine; Mice; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Zinc; Zinc Isotopes | 1967 |
Proton release during the reductive half-reaction of D-amino acid oxidase.
Topics: Alanine; Anaerobiosis; Binding, Competitive; D-Amino-Acid Oxidase; Hydrogen-Ion Concentration; Kinetics; Proline; Substrate Specificity | 1982 |
Resonance Raman on the purple intermediates of the flavoenzyme D-amino acid oxidase.
Topics: Alanine; Animals; Chemical Phenomena; Chemistry; D-Amino-Acid Oxidase; Flavins; Imino Acids; Kidney; Proline; Spectrum Analysis, Raman; Swine | 1982 |
On the structures of flavoprotein D-amino acid oxidase purple intermediates. A resonance Raman study.
Topics: Alanine; Animals; D-Amino-Acid Oxidase; Flavin-Adenine Dinucleotide; Flavoproteins; Kidney; Kinetics; Proline; Protein Binding; Protein Conformation; Spectrum Analysis, Raman; Swine | 1983 |
[Clinicohematologic effects of hemoglobin Altdorf (alpha 2 beta 2 135 Ala replaced by Pro)].
Topics: Adolescent; Alanine; Child, Preschool; Erythrocytes; Female; Heinz Bodies; Hemoglobinopathies; Hemoglobins, Abnormal; Hemolysis; Humans; Italy; Male; Middle Aged; Pedigree; Phenylhydrazines; Proline | 1980 |
Alanine-resistant mutants of Chinese hamster ovary cells, CHO-K1, producing increases in velocity of proline transport through the A, ASC, and P systems.
Topics: Alanine; Animals; Biological Transport; Cell Line; Cricetinae; Cricetulus; Drug Resistance; Female; Glutamine; Kinetics; Mutation; Ovary; Proline; Serine | 1983 |
Study of the mechanism of release of [3H]GABA from a teleost retina in vitro.
Topics: Alanine; Animals; Calcium; Calcium Channel Blockers; Fishes; gamma-Aminobutyric Acid; Nipecotic Acids; Potassium; Proline; Retina; Sodium; Tetrodotoxin; Veratridine | 1984 |
Evidence that cycloleucine affects the high-affinity systems of amino acid uptake in cultured human fibroblasts.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Cells, Cultured; Cycloleucine; Depression, Chemical; Fibroblasts; Humans; Kinetics; Leucine; Proline; Sodium | 1984 |
Measurement of changes in amino acids related to total collagen in fibrotic human liver.
Topics: Adult; Alanine; Amino Acids; Bile Ducts; Biopsy; Child; Child, Preschool; Chromatography, Gas; Collagen; Glycine; Humans; Hydroxylysine; Hydroxyproline; Infant; Liver; Liver Cirrhosis; Proline | 1984 |
Bovine beta-crystallin complementary DNA clones. Alternating proline/alanine sequence of beta B1 subunit originates from a repetitive DNA sequence.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Cattle; Cloning, Molecular; Crystallins; DNA; Electrophoresis, Polyacrylamide Gel; Isoelectric Focusing; Lens, Crystalline; Macromolecular Substances; Mice; Nucleic Acid Hybridization; Proline; Repetitive Sequences, Nucleic Acid; RNA, Messenger | 1984 |
Proline- and alanine-rich N-terminal extension of the basic bovine beta-crystallin B1 chains.
Topics: Alanine; Amino Acid Sequence; Animals; Cattle; Chemical Phenomena; Chemistry; Crystallins; Peptide Fragments; Proline | 1983 |
Prevention of Staphylococcus aureus lysis.
Topics: Alanine; Bacteriolysis; Culture Media; Proline; Staphylococcus aureus | 1983 |
Conformation and mobility of tyrosine side chain in tetrapeptides. Specific effects of cis- and trans-proline in Tyr-Pro- and Pro-Tyr-segments.
Topics: Alanine; Circular Dichroism; Isomerism; Models, Molecular; Oligopeptides; Oxytocin; Proline; Protein Conformation; Structure-Activity Relationship; Tyrosine | 1983 |
Actions of gamma-aminobutyric acid on neurones of guinea-pig myenteric plexus.
Topics: Acetylcholine; Alanine; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glycine; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscimol; Myenteric Plexus; Neural Conduction; Neuromuscular Depolarizing Agents; Neurons; Nipecotic Acids; Picrotoxin; Proline; Tetrodotoxin | 1984 |
L-Proline transport in Saccharomyces cerevisiae.
Topics: 2,4-Dinitrophenol; Alanine; Biological Transport; Dinitrophenols; Hydrogen-Ion Concentration; Kinetics; Proline; Saccharomyces cerevisiae; Temperature | 1982 |
Genetic control of a shared idiotype among antibodies directed to distinct specificities.
Topics: Alanine; Animals; Antibody Diversity; Antibody Specificity; Binding Sites, Antibody; Genes; Glutamates; Immune Sera; Immunoglobulin Idiotypes; Lysine; Mice; Mice, Inbred Strains; Mutation; Peptides; Phenylalanine; Proline; Tyrosine | 1980 |
Amino acid transport via the red cell anion transport system.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Alanine; Amino Acids; Biological Transport; Carrier Proteins; Cysteine; Depression, Chemical; Erythrocytes; Glycine; Humans; In Vitro Techniques; Proline; Serine; Threonine; Valine | 1981 |
Production of amino acids by analog-resistant mutants of the cyanobacterium Spirulina platensis.
Topics: Alanine; Azetidinecarboxylic Acid; Cyanobacteria; Drug Resistance, Microbial; Ethionine; Methionine; p-Fluorophenylalanine; Phenylalanine; Proline; Tryptophan | 1981 |
Effect of non-essential amino acids on fetal rat pancreatic growth and insulin secretion in vitro.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Glycine; Insulin; Insulin Secretion; Organ Culture Techniques; Pancreas; Proline; Rats; Rats, Inbred Strains; Serine | 1981 |
Multiple transport pathways for neutral amino acids in rabbit jejunal brush border vesicles.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Cell Membrane; Diffusion; Jejunum; Kinetics; Lysine; Male; Methionine; Microvilli; Phenylalanine; Proline; Rabbits; Sodium | 1982 |
Neutral amino acid transport in Leishmania promastigotes.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Kinetics; Leishmania; Potassium Cyanide; Proline | 1983 |
Conformation of model, alanine and proline containing tetrapeptides in water. Comparison of 13C-n.m.r. and CD results.
Topics: Alanine; Circular Dichroism; Magnetic Resonance Spectroscopy; Oligopeptides; Proline; Protein Conformation; Structure-Activity Relationship; Water | 1983 |
Glucose induces two amino acid transport systems in Chlorella.
Topics: Alanine; Amino Acids; Arginine; Biological Transport, Active; Carrier Proteins; Chlorophyta; Glucose; Proline | 1981 |
A possible rôle for acid phosphatase in gamma-amino-n-butyrate uptake in Aspergillus nidulans.
Topics: Acid Phosphatase; Alanine; Aspergillus nidulans; gamma-Aminobutyric Acid; Membrane Transport Proteins; Mutation; Proline; Pyrrolidinones; Pyrroline Carboxylate Reductases | 1980 |
Metabolic effects of septicaemia in newborn and young infants with particular reference to the plasma free amino acids.
Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Bacterial Infections; Escherichia coli Infections; Glycine; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Phenylalanine; Proline; Pseudomonas Infections; Sepsis; Tyrosine | 1980 |
Steric effect exerted by the proline residue on the antecedent alanine residue.
Topics: Alanine; Amino Acid Sequence; Magnetic Resonance Spectroscopy; Molecular Conformation; Oligopeptides; Proline; Protein Conformation; Structure-Activity Relationship | 1982 |
Amino acid-evoked membrane potential and resistance changes in pancreatic acinar cells.
Topics: Alanine; Animals; Calcium; Dose-Response Relationship, Drug; Electric Conductivity; Evoked Potentials; In Vitro Techniques; Membrane Potentials; Mice; Ouabain; Pancreas; Proline; Sodium; Valine | 1980 |
Rigidity of the polypeptide backbone in the triple-stranded collagen molecule.
Topics: Alanine; Collagen; Peptide Fragments; Proline; Protein Conformation | 1981 |
Circular dichroism of type 13 beta -turn in linear tripeptides containing L-proline and D-alanine.
Topics: Alanine; Circular Dichroism; Hydrogen Bonding; Leucine; Oligopeptides; Proline; Protein Conformation; Structure-Activity Relationship; Valine | 1981 |
The transport of neutral amino acids in cultured human fibroblasts.
Topics: Alanine; Amino Acids; Biological Transport; Cells, Cultured; Fibroblasts; Humans; Kinetics; Leucine; Osmolar Concentration; Proline; Skin | 1980 |
Inhibition of urea-cycle activity by high concentrations of alanine.
Topics: Alanine; Ammonia; Animals; Argininosuccinate Synthase; Cytosol; In Vitro Techniques; Liver; Male; Proline; Rats; Urea | 1980 |
Amino acid metabolism by new-born rat heart cells in monolayer cultures.
Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Cells, Cultured; Glucose; Glycine; Myocardium; Proline; Rats; Time Factors | 1980 |
Reactivity of individual functional groups of histones in calf thymus chromatin.
Topics: Alanine; Animals; Cattle; Chromatin; Dinitrofluorobenzene; Histones; Hydrogen-Ion Concentration; Proline; Sulfhydryl Compounds; Thymus Gland | 1980 |
Hb Toyoake: beta 142 (H20) Ala replaced by Pro. A new unstable hemoglobin with high oxygen affinity.
Topics: Adult; Alanine; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis, Cellulose Acetate; Electrophoresis, Starch Gel; Hemoglobin A; Hemoglobins, Abnormal; Hemolysis; Humans; Male; Oxygen; Proline | 1981 |
Decreased cysteine and proline synthesis in parenterally fed, premature infants.
Topics: Alanine; Amino Acids; Aspartic Acid; Birth Weight; Blood Glucose; Carbon Isotopes; Cysteine; Electrolytes; Energy Intake; Female; Food, Formulated; Gas Chromatography-Mass Spectrometry; Gestational Age; Glucose; Glutamic Acid; Glycine; Humans; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Lipids; Male; Parenteral Nutrition; Parenteral Nutrition Solutions; Proline; Serine; Solutions | 1995 |
Stabilisation of purified human collagenase by site-directed mutagenesis.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Collagenases; DNA Primers; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Escherichia coli; Glutathione Transferase; Humans; Isoleucine; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Proline; Recombinant Fusion Proteins; Recombinant Proteins | 1995 |
Comparison between thymidylate synthase B of Bacillus subtilis ATCC6633 and 168.
Topics: Alanine; Amino Acid Sequence; Bacillus subtilis; Kinetics; Molecular Sequence Data; Point Mutation; Proline; Species Specificity; Thymidylate Synthase | 1995 |
Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions.
Topics: Adaptor Proteins, Signal Transducing; Alanine; Amino Acid Sequence; Arginine; Binding Sites; CSK Tyrosine-Protein Kinase; Glycine; GRB2 Adaptor Protein; Guanine Nucleotide Exchange Factors; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Oligopeptides; Peptides; Proline; Proline-Rich Protein Domains; Protein Conformation; Protein Structure, Secondary; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins pp60(c-src); src-Family Kinases | 1994 |
Cytotoxic T cell recognition of a human melanoma derived peptide with a carboxyl-terminal alanine-proline sequence.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Epitopes; HLA Antigens; Humans; Melanoma; Molecular Sequence Data; Neoplasm Proteins; Proline; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured; Vaccines | 1995 |
Identification of structural determinants controlling human and mouse stromelysin-3 proteolytic activities.
Topics: Alanine; Animals; Base Sequence; Caseins; Cloning, Molecular; Collagen; DNA Primers; DNA, Complementary; Humans; Kinetics; Laminin; Matrix Metalloproteinase 11; Metalloendopeptidases; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Proline; Recombinant Proteins; Species Specificity; Substrate Specificity | 1995 |
Identification of three proline-directed phosphorylation sites in the human androgen receptor.
Topics: Alanine; Animals; Binding Sites; Humans; Mutation; Phosphorylation; Proline; Receptors, Androgen; Sequence Deletion; Serine; Structure-Activity Relationship; Transcription, Genetic | 1995 |
An apoptotic defect in lens differentiation caused by human p53 is rescued by a mutant allele.
Topics: Aging; Alanine; Alleles; Animals; Apoptosis; Arginine; Cell Differentiation; Codon; Epithelial Cells; Gene Expression; Genes, p53; Genetic Therapy; Humans; Lens, Crystalline; Mice; Mice, Transgenic; Microphthalmos; Point Mutation; Proline; Tumor Suppressor Protein p53; Valine | 1995 |
Rhodopsin mutation proline347-to-alanine in a family with autosomal dominant retinitis pigmentosa indicates an important role for proline at position 347.
Topics: Alanine; Amino Acid Sequence; Base Sequence; DNA; Female; Genes, Dominant; Humans; Male; Molecular Sequence Data; Mutation; Pedigree; Proline; Retinitis Pigmentosa; Rhodopsin | 1995 |
Removal of feedback inhibition of delta 1-pyrroline-5-carboxylate synthetase, a bifunctional enzyme catalyzing the first two steps of proline biosynthesis in plants.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Alanine; Amino Acid Sequence; Base Sequence; Blotting, Western; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cloning, Molecular; DNA, Complementary; Durapatite; Escherichia coli; Feedback; Glutamic Acid; Kinetics; Macromolecular Substances; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Oxidoreductases Acting on CH-NH Group Donors; Phenylalanine; Plants; Point Mutation; Proline; Recombinant Proteins | 1995 |
The effect of protein concentration on ion binding.
Topics: Alanine; Animals; Asparagine; Binding Sites; Calbindins; Calcium; Cattle; Genes, Synthetic; Ions; Kinetics; Magnesium; Magnetic Resonance Spectroscopy; Methionine; Monte Carlo Method; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Proline; Protein Conformation; Proteins; Recombinant Proteins; S100 Calcium Binding Protein G | 1995 |
The choice of reducing substrate is altered by replacement of an alanine by a proline in the FAD domain of a bispecific NAD(P)H-nitrate reductase from birch.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Codon; Flavin-Adenine Dinucleotide; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Nitrate Reductase (NAD(P)H); Nitrate Reductases; Oxidation-Reduction; Proline; Recombinant Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Trees | 1995 |
Insulin receptor substrate-1 gene mutations in NIDDM; implications for the study of polygenic disease.
Topics: Adult; Aged; Alanine; Arginine; Base Sequence; Case-Control Studies; Codon; Deoxyribonucleases, Type II Site-Specific; Diabetes Mellitus, Type 2; DNA Primers; Female; Finland; Genotype; Glycine; Humans; India; Insulin Receptor Substrate Proteins; Male; Middle Aged; Molecular Sequence Data; Pedigree; Phosphoproteins; Point Mutation; Polymerase Chain Reaction; Proline; Reference Values; Restriction Mapping; Risk Factors | 1995 |
Kinetics of the reduction of cytochrome b5 with mutations in its membrane-binding domain.
Topics: Alanine; Amino Acid Sequence; Animals; Cloning, Molecular; Cytochrome P-450 Enzyme System; Cytochromes b5; Genes, Synthetic; Glutamates; Glutamic Acid; Kinetics; Lysine; Mutagenesis, Site-Directed; Oxidation-Reduction; Point Mutation; Proline; Rats; Recombinant Proteins; Saccharomyces cerevisiae; Spectrophotometry | 1994 |
Dietary citrulline but not ornithine counteracts dietary arginine deficiency in rats by increasing splanchnic release of citrulline.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Blood Flow Velocity; Body Weight; Citrulline; Creatinine; Diet; Food; Glutamic Acid; Glutamine; Male; Ornithine; Orotic Acid; Proline; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Urea | 1994 |
Affinity of native kappa-bungarotoxin and site-directed mutants for the muscle nicotinic acetylcholine receptor.
Topics: Alanine; Amino Acid Sequence; Animals; Bungarotoxins; Cell Division; Cell Line; Chick Embryo; Dose-Response Relationship, Drug; Fibroblasts; Glutamine; Lysine; Mice; Molecular Sequence Data; Muscle, Skeletal; Mutagenesis, Site-Directed; Proline; Quail; Receptors, Nicotinic; Recombinant Proteins; Sequence Homology, Amino Acid; Snake Venoms; Tryptophan | 1994 |
The structure of Fis mutant Pro61Ala illustrates that the kink within the long alpha-helix is not due to the presence of the proline residue.
Topics: Alanine; Base Sequence; Carrier Proteins; DNA-Binding Proteins; Factor For Inversion Stimulation Protein; Integration Host Factors; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Proline; Protein Conformation | 1994 |
Folding pathway of guanidine-denatured disulfide-intact wild-type and mutant bovine pancreatic ribonuclease A.
Topics: Alanine; Animals; Binding Sites; Cattle; Cytidine Monophosphate; Disulfides; Guanidine; Guanidines; Kinetics; Mutagenesis, Site-Directed; Point Mutation; Proline; Protein Denaturation; Protein Folding; Recombinant Proteins; Ribonuclease, Pancreatic; Tyrosine | 1994 |
Changes in serum amino acid concentrations during prolonged endurance running.
Topics: Adult; Alanine; Amino Acids; Blood Glucose; Fatty Acids, Nonesterified; Female; Humans; Male; Middle Aged; Osmolar Concentration; Physical Endurance; Proline; Running; Time Factors; Urea | 1993 |
Generation of a non-prolyl cis peptide bond in ribonuclease T1.
Topics: Alanine; Catalysis; Magnetic Resonance Spectroscopy; Peptides; Proline; Protein Conformation; Ribonuclease T1 | 1994 |
Molecular scanning of the glycogen synthase and insulin receptor substrate-1 genes in Japanese subjects with non-insulin-dependent diabetes mellitus.
Topics: Alanine; Alleles; Amino Acid Sequence; Arginine; Base Sequence; Blood Glucose; Diabetes Mellitus, Type 2; DNA Primers; Genotype; Glycated Hemoglobin; Glycine; Glycogen Synthase; Humans; Insulin; Insulin Receptor Substrate Proteins; Japan; Middle Aged; Molecular Sequence Data; Phosphoproteins; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Proline; Repetitive Sequences, Nucleic Acid | 1994 |
The specificity of clostripain from Clostridium histolyticum. Mapping the S' subsites via acyl transfer to amino acid amides and peptides.
Topics: Acylation; Alanine; Amides; Amino Acid Sequence; Binding Sites; Clostridium; Cysteine Endopeptidases; Kinetics; Models, Chemical; Molecular Sequence Data; Peptides; Proline; Protein Precursors; Substrate Specificity | 1994 |
Hypertonic upregulation of amino acid transport system A in vascular smooth muscle cells.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Cell Line; Culture Media; Hypertonic Solutions; Muscle, Smooth, Vascular; Ouabain; Proline; Rats; Sodium; Sucrose | 1994 |
The plasma amino acid response to cafeteria feeding and essential-amino acid gavage in weaning rats.
Topics: Alanine; Amino Acids; Amino Acids, Essential; Animals; Cysteine; Diet; Female; Food Services; Glutamates; Glutamic Acid; Glutamine; Glycine; Hydroxyproline; Methionine; Ornithine; Proline; Rats; Rats, Wistar | 1993 |
The dopamine DA-1 receptor agonist fenoldopam enhances amino-acid-induced hyperemia in dogs.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Alanine; Amino Acids; Animals; Dogs; Dopamine Agents; Drug Synergism; Female; Fenoldopam; Glomerular Filtration Rate; Hyperemia; Proline; Renal Circulation; Serine; Sodium | 1993 |
Low-molecular-mass human salivary mucin, MG2: structure and binding of Pseudomonas aeruginosa.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Fimbriae, Bacterial; Glycopeptides; Humans; Isoleucine; Leucine; Molecular Sequence Data; Mucins; Oligosaccharides; Phenylalanine; Proline; Protein Binding; Pseudomonas aeruginosa; Salivary Proteins and Peptides; Trypsin; Valine | 1993 |
Glial cells transform glucose to alanine, which fuels the neurons in the honeybee retina.
Topics: Alanine; Amino Acids; Animals; Bees; Glucose; Glycogen; Light; Mitochondria; Neuroglia; Neurons; Phosphorylation; Photic Stimulation; Photoreceptor Cells, Invertebrate; Proline; Retina; Substrate Specificity; Transaminases | 1994 |
Energetics of alanine, lysine, and proline transport in cytoplasmic membranes of the polyphosphate-accumulating Acinetobacter johnsonii strain 210A.
Topics: Acinetobacter; Alanine; Biological Transport; Carrier Proteins; Energy Metabolism; Glucose; Glucose 1-Dehydrogenase; Glucose Dehydrogenases; Kinetics; Lysine; Membrane Potentials; Membranes; Polyphosphates; Proline; Protons; Sodium | 1994 |
Specificity of the imino acid carrier in rat small intestine.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Carrier Proteins; gamma-Aminobutyric Acid; Imino Acids; Intestine, Small; Male; Microvilli; Proline; Rats; Species Specificity; Taurine | 1994 |
Structure and energetics of a non-proline cis-peptidyl linkage in a proline-202-->alanine carbonic anhydrase II variant.
Topics: Alanine; Binding Sites; Carbonic Anhydrases; Catalysis; Crystallography, X-Ray; Enzyme Stability; Humans; Molecular Structure; Proline; Protein Conformation; Stereoisomerism; Thermodynamics | 1993 |
A novel mutation and a polymorphism in the X chromosome located pyruvate dehydrogenase E1 alpha gene (PDHA1).
Topics: Alanine; Amino Acid Sequence; Base Sequence; Child; Chromosome Mapping; Conserved Sequence; Female; Humans; Male; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Proline; Pyruvate Dehydrogenase Complex; X Chromosome | 1993 |
The positive-acting sulfur regulatory protein CYS3 of Neurospora crassa: nuclear localization, autogenous control, and regions required for transcriptional activation.
Topics: Alanine; Arylsulfatases; Blotting, Western; Cystathionine gamma-Lyase; DNA-Binding Proteins; DNA, Fungal; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fungal Proteins; Genes, Fungal; Genes, Regulator; Leucine Zippers; Mutagenesis; Neurospora crassa; Nuclear Proteins; Proline; Recombinant Fusion Proteins; Saccharomyces cerevisiae Proteins; Sequence Analysis, DNA; Sequence Deletion; Sulfur; Trans-Activators; Transcription Factors; Transcriptional Activation | 1993 |
Transthyretin-related TTR hereditary amyloidosis of the vitreous body. Clinical and molecular characterization in two Italian families.
Topics: Adult; Aged; Alanine; Amyloidosis; Eye Diseases; Female; Humans; Lens Diseases; Male; Middle Aged; Mutation; Pedigree; Prealbumin; Proline; Ultrasonography; Vitreous Body | 1993 |
Substrate recognition by ceramide-activated protein kinase. Evidence that kinase activity is proline-directed.
Topics: Alanine; Amino Acid Sequence; Ceramides; Chromatography, High Pressure Liquid; Humans; Intracellular Membranes; Kinetics; Leukemia, Promyelocytic, Acute; Microsomes; Oligopeptides; Phosphopeptides; Proline; Protein Serine-Threonine Kinases; Substrate Specificity; Tumor Cells, Cultured | 1993 |
Identification of the cleavage site and determinants required for poliovirus 3CPro-catalyzed cleavage of human TATA-binding transcription factor TBP.
Topics: 3C Viral Proteases; Alanine; Amino Acid Sequence; Base Sequence; Cysteine Endopeptidases; Glutamine; Glycine; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Poliovirus; Proline; Protein Precursors; Protein Processing, Post-Translational; Recombinant Proteins; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Substrate Specificity; TATA Box; Transcription Factor TFIID; Transcription Factors; Viral Proteins | 1993 |
Identification and molecular characterization of E-MAP-115, a novel microtubule-associated protein predominantly expressed in epithelial cells.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Antibodies, Monoclonal; Base Sequence; Cell Line; Cloning, Molecular; DNA; Dogs; Epithelial Cells; Epithelium; Fibroblasts; Fluorescent Antibody Technique; Humans; Immunoblotting; Kidney; Microscopy, Electron; Microtubule-Associated Proteins; Microtubules; Molecular Sequence Data; Nocodazole; Precipitin Tests; Proline; Sequence Analysis, DNA; Transfection; Vero Cells | 1993 |
Active transport of L-proline in the protozoan parasite Trypanosoma brucei brucei.
Topics: Adenosine Triphosphate; Alanine; Animals; Azetidinecarboxylic Acid; Binding, Competitive; Biological Transport, Active; Cell Membrane Permeability; Cysteine; Digitonin; Hydrogen-Ion Concentration; Hydroxyproline; Iodoacetates; Iodoacetic Acid; Kinetics; Potassium Cyanide; Proline; Temperature; Thermodynamics; Trypanosoma brucei brucei | 1993 |
Stability and folding kinetics of ribonuclease T1 are strongly altered by the replacement of cis-proline 39 with alanine.
Topics: Alanine; Base Sequence; Circular Dichroism; DNA; Enzyme Stability; Guanidine; Guanidines; Kinetics; Molecular Sequence Data; Proline; Protein Denaturation; Protein Folding; Ribonuclease T1 | 1993 |
Kinetic models for unfolding and refolding of ribonuclease T1 with substitution of cis-proline 39 by alanine.
Topics: Alanine; Amino Acid Isomerases; Carrier Proteins; Catalysis; Circular Dichroism; Humans; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Mutation; Peptidylprolyl Isomerase; Proline; Protein Denaturation; Protein Folding; Recombinant Proteins; Ribonuclease T1 | 1993 |
Hydration structure of a collagen peptide.
Topics: Alanine; Amino Acid Sequence; Collagen; Crystallography, X-Ray; Models, Molecular; Molecular Sequence Data; Proline; Protein Conformation; Protein Folding; Water | 1995 |
Substitutions of proline 42 to alanine and methionine 46 to asparagine around the RGD domain of the neurotoxin dendroaspin alter its preferential antagonism to that resembling the disintegrin elegantin.
Topics: Alanine; Amino Acid Sequence; Asparagine; Chromatography, Affinity; Chromatography, High Pressure Liquid; Elapid Venoms; Escherichia coli; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligopeptides; Peptides; Platelet Aggregation Inhibitors; Proline; Recombinant Proteins; Sequence Homology, Amino Acid | 1996 |
Resolved two-dimensional anisotropic-chemical-shift/heteronuclear dipolar coupling powder-pattern spectra by three-dimensional solid-state NMR spectroscopy.
Topics: Alanine; Carbon; Crystallography; Electron Spin Resonance Spectroscopy; Glycine; Hydrogen; Image Enhancement; Magnetic Resonance Spectroscopy; Nitrogen; Oligopeptides; Proline | 1996 |
Water exchange filter with improved sensitivity (WEX II) to study solvent-exchangeable protons. Application to the consensus zinc finger peptide CP-1.
Topics: Alanine; Amides; Consensus Sequence; Hydrogen Bonding; Image Enhancement; Magnetic Resonance Spectroscopy; Peptide Fragments; Proline; Protein Conformation; Protons; Rotation; Solvents; Water; Zinc Fingers | 1996 |
Multiconformational analysis of solution NOE data for the Ac-(L)proline-(D)alanine-NHMe dipeptide in a nonprotic solvent.
Topics: Alanine; Algorithms; Humans; Magnetic Resonance Spectroscopy; Peptides; Proline; Protein Conformation | 1995 |
Folding and unfolding kinetics of the proline-to-alanine mutants of bovine pancreatic ribonuclease A.
Topics: Alanine; Animals; Cattle; Genes, Synthetic; Guanidine; Guanidines; Isomerism; Kinetics; Models, Chemical; Mutation; Pancreas; Proline; Protein Denaturation; Protein Folding; Recombinant Proteins; Ribonuclease, Pancreatic | 1996 |
Class III POU genes: generation of homopolymeric amino acid repeats under GC pressure in mammals.
Topics: Alanine; Amino Acid Sequence; Animals; Base Composition; Base Sequence; Bombyx; Caenorhabditis elegans; Codon; DNA Primers; Drosophila melanogaster; Evolution, Molecular; Genetic Variation; Glycine; Humans; Mammals; Mice; Molecular Sequence Data; Planarians; Polymerase Chain Reaction; Proline; Rats; Repetitive Sequences, Nucleic Acid; Restriction Mapping; Sequence Homology, Amino Acid; Transcription Factors; Xenopus laevis; Zebrafish | 1996 |
Changes in the intracellular free amino acid pool in human saphenous vein tissue culture.
Topics: Aged; Alanine; Amino Acids; Asparagine; Aspartic Acid; Culture Techniques; Cytosol; Glutamic Acid; Glutamine; Glycine; Humans; Middle Aged; Proline; Saphenous Vein; Serine; Taurine | 1996 |
1H-NMR and 13C-NMR investigation of complexes of Mn2+ with ocytocin analogues in (2H6)dimethylsulfoxide.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Carbon Isotopes; Cysteine; Deuterium; Dimethyl Sulfoxide; Glutamine; Hydrogen; Magnetic Resonance Spectroscopy; Manganese; Models, Molecular; Molecular Sequence Data; Oxytocin; Proline; Protein Binding; Protein Conformation; Sarcosine; Sulfhydryl Compounds; Thermodynamics; Threonine | 1996 |
Differential regulation of c-Myb-induced transcription activation by a phosphorylation site in the negative regulatory domain.
Topics: Alanine; Animals; Avian Myeloblastosis Virus; Binding Sites; Cell Line; Chlorocebus aethiops; DNA; Gene Expression Regulation; Mice; Molecular Weight; Phosphorylation; Proline; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Serine; Structure-Activity Relationship; Trans-Activators; Transcription, Genetic; Transcriptional Activation | 1996 |
Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells.
Topics: Alanine; Amino Acid Sequence; Animals; Breast Neoplasms; Cell Division; Chemotaxis; Drosophila; Female; Glycine; Histidine; Humans; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Mutagenesis, Site-Directed; Neuroblastoma; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Phosphorylation; Polymerase Chain Reaction; Proline; Recombinant Proteins; Serine; Transcription Factors; Transfection; Tumor Cells, Cultured | 1996 |
First case of sporadic protein S deficiency due to a novel candidate mutation, Ala 484-->Pro, in the protein S active gene (PROS1).
Topics: Alanine; Alleles; Animals; Cattle; Humans; Mice; Point Mutation; Polymorphism, Genetic; Proline; Protein C; Protein S; Protein S Deficiency; Rats | 1996 |
Rate of pellicle formation in vivo.
Topics: Adsorption; Adult; Alanine; Amino Acids; Dental Deposits; Dental Enamel; Dental Pellicle; Glutamic Acid; Glycine; Humans; Lysine; Middle Aged; Proline; Salivary Proteins and Peptides; Spectrum Analysis; Time Factors | 1995 |
Serine 752 in the cytoplasmic domain of the beta 3 integrin subunit is not required for alpha v beta 3 postreceptor signaling events.
Topics: Alanine; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antigens, CD; Cell Adhesion; CHO Cells; Cricetinae; Cytoskeleton; Extracellular Matrix Proteins; Fibrinogen; Genetic Complementation Test; Humans; Integrin beta3; Molecular Sequence Data; Oligopeptides; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Point Mutation; Proline; Protein Binding; Receptors, Vitronectin; Recombinant Fusion Proteins; Sequence Alignment; Serine; Signal Transduction; Thrombasthenia; Transfection; Vitronectin; von Willebrand Factor | 1996 |
Characterization of herpes simplex virus type 1 recombinants with mutations in the cytoplasmic tail of glycoprotein H.
Topics: Alanine; Animals; Binding Sites; Cell Line; Chlorocebus aethiops; COS Cells; Herpesvirus 1, Human; Humans; Mutation; Point Mutation; Proline; Recombination, Genetic; Sequence Deletion; Serine; Structure-Activity Relationship; Valine; Vero Cells; Viral Envelope Proteins; Viral Plaque Assay | 1996 |
Conformational investigation of alpha,beta-dehydropeptides. VII. Conformation of Ac-Pro-deltaAla-NHCH3 and Ac-Pro-(E)-deltaAbu-NHCH3: comparison with (Z)-substituted alpha,beta-dehydropeptides.
Topics: Alanine; Circular Dichroism; Dipeptides; Magnetic Resonance Spectroscopy; Proline; Protein Structure, Secondary; Solvents; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; X-Ray Diffraction | 1996 |
Blood-endothelial cell and blood-brain transport of L-proline, alpha-aminoisobutyric acid, and L-alanine.
Topics: Alanine; Aminoisobutyric Acids; Animals; Biological Transport; Blood-Brain Barrier; Endothelium, Vascular; Male; Membranes; Proline; Rats; Rats, Sprague-Dawley; Regression Analysis | 1996 |
Structural requirements and thermodynamics of the interaction of proline peptides with profilin.
Topics: Acanthamoeba; Alanine; Animals; Binding Sites; Calorimetry; Circular Dichroism; Contractile Proteins; Entropy; Glycine; Humans; In Vitro Techniques; Microfilament Proteins; Molecular Structure; Oligopeptides; Peptides; Profilins; Proline; Protein Conformation; Protein Structure, Secondary; Spectrometry, Fluorescence; Thermodynamics | 1996 |
P1148A in fibrillin-1 is not a mutation anymore.
Topics: Adult; Alanine; Ethnicity; Female; Fibrillin-1; Fibrillins; Humans; Male; Microfilament Proteins; Point Mutation; Polymorphism, Genetic; Proline | 1997 |
Mechanisms of amino acid-induced insulin secretion from the glucose-responsive BRIN-BD11 pancreatic B-cell line.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Calcium Channel Blockers; Cell Line; Diazoxide; Dose-Response Relationship, Drug; Glucose; Glutamine; Glyceraldehyde; Glycine; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Lysine; Potassium Channels; Proline; Radioimmunoassay; Rats; Serine; Stimulation, Chemical; Verapamil | 1996 |
Uptake and release of 2-aminoisobutyrate by Leishmania donovani: culture-age dependent effects of osmolality and of protein kinase inhibitors.
Topics: Alanine; Aminoisobutyric Acids; Animals; Biological Transport; Cell Division; Cellular Senescence; Enzyme Inhibitors; Genistein; Glucose; Glutamic Acid; Hypertonic Solutions; Isoflavones; Leishmania donovani; Osmolar Concentration; Proline; Protein Kinase Inhibitors; Staurosporine | 1996 |
Distinct sequences of AKH/RPCH family members in beetle (Scarabaeus-species) corpus cardiacum contain three aromatic amino acid residues.
Topics: Alanine; Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Coleoptera; Insect Hormones; Invertebrate Hormones; Oligopeptides; Proline; Pyrrolidonecarboxylic Acid; Sequence Homology, Amino Acid; Species Specificity | 1997 |
Serine319 and 321 are functional in isocitrate lyase from Escherichia coli.
Topics: Alanine; Asparagine; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression Regulation, Bacterial; Glycine; Histidine; Isocitrate Lyase; Isocitrates; Kinetics; Magnesium; Mutagenesis, Site-Directed; Oligonucleotides; Plasmids; Proline; Sequence Alignment; Serine; Threonine | 1997 |
Involvement of metabotropic glutamate receptors in Gi- and Gs-dependent modulation of adenylate cyclase activity induced by a novel cognition enhancer NS-105 in rat brain.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic alpha-Agonists; Alanine; Animals; Baclofen; Brimonidine Tartrate; Cell Membrane; Cerebral Cortex; Cholera Toxin; Cognition; Colforsin; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Antagonists; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Isoproterenol; Kinetics; Male; Manganese; Pertussis Toxin; Piperidines; Proline; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Neurotransmitter; Virulence Factors, Bordetella; Yohimbine | 1997 |
The pathogenicity of the Pro1148Ala substitution in the FBN1 gene: causing or predisposing to Marfan syndrome and aortic aneurysm, or clinically innocent?
Topics: Alanine; Amino Acid Sequence; Animals; Aortic Aneurysm; Asia; Base Sequence; Biological Evolution; Cattle; Cells, Cultured; Chromosome Mapping; Chromosomes, Human, Pair 15; Connective Tissue Diseases; Disease Susceptibility; DNA Primers; Drosophila; Exons; Fibrillin-1; Fibrillins; Homozygote; Humans; Introns; Latin America; Marfan Syndrome; Mice; Microfilament Proteins; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Proline; Racial Groups; Reference Values; Skin; United States | 1997 |
Characterization of the substrate specificity of the major cysteine protease (cruzipain) from Trypanosoma cruzi using a portion-mixing combinatorial library and fluorogenic peptides.
Topics: Alanine; Animals; Antigens, Protozoan; Cathepsin L; Cathepsins; Cysteine Endopeptidases; Databases, Factual; Endopeptidases; Enzyme Precursors; Fluorescent Dyes; Glycoproteins; Humans; Hydrolysis; Peptides; Proline; Protozoan Proteins; Structure-Activity Relationship; Substrate Specificity; Trypanosoma cruzi | 1997 |
Structure-function studies of the brain-type glucose transporter, GLUT3: alanine-scanning mutagenesis of putative transmembrane helix VIII and an investigation of the role of proline residues in transport catalysis.
Topics: Alanine; Amino Acid Sequence; Animals; Brain Chemistry; Female; Glucose; Glucose Transporter Type 3; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Proline; Protein Structure, Secondary; Structure-Activity Relationship; Xenopus laevis | 1997 |
Kinetic folding and cis/trans prolyl isomerization of staphylococcal nuclease. A study by stopped-flow absorption, stopped-flow circular dichroism, and molecular dynamics simulations.
Topics: Alanine; Circular Dichroism; Computer Simulation; Glycine; Kinetics; Micrococcal Nuclease; Mutagenesis, Insertional; Proline; Protein Folding; Spectrophotometry; Stereoisomerism; Thermodynamics | 1997 |
Identification of four amino acids in the gastrin-releasing peptide receptor that are required for high affinity agonist binding.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Animals; Arginine; Binding Sites; Bombesin; Gastrin-Releasing Peptide; Glutamine; Guinea Pigs; Humans; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Point Mutation; Proline; Protein Binding; Receptors, Bombesin; Structure-Activity Relationship | 1997 |
Which amino-acids do serum and hemofiltrate of critically ill patients with acute renal failure contain?
Topics: Alanine; Amino Acids; Asparagine; Citrulline; Cystathionine; Ethanolamines; Extracorporeal Circulation; Glutamine; Glycine; Hemofiltration; Histidine; Humans; Kidney Failure, Chronic; Lactic Acid; Methionine; Proline | 1997 |
Efflux of compatible solutes in Corynebacterium glutamicum mediated by osmoregulated channel activity.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Amino Acids, Diamino; Betaine; Corynebacterium; Glutamic Acid; Glycine; Homeostasis; Hypotonic Solutions; Ion Channels; Kinetics; Lysine; Membrane Potentials; Osmolar Concentration; Potassium; Proline; Sodium | 1997 |
Visual and chemical release of feeding behavior in adult rainbow trout.
Topics: Alanine; Amino Acids; Animals; Arginine; Betaine; Bites and Stings; Dose-Response Relationship, Drug; Feeding Behavior; Glycine; Leucine; Movement; Olfactory Pathways; Oncorhynchus mykiss; Photic Stimulation; Proline; Propionates; Reproducibility of Results; Stimulation, Chemical; Swimming; Taste; Valine | 1997 |
Extensible collagen in mussel byssus: a natural block copolymer.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Biopolymers; Bivalvia; Collagen; DNA, Complementary; Elasticity; Elastin; Fibroins; Glycine; Histidine; Molecular Sequence Data; Proline; Protein Conformation; Protein Precursors; Protein Structure, Secondary; Sequence Alignment; Serine | 1997 |
The nutritive function of glia is regulated by signals released by neurons.
Topics: Alanine; Ammonia; Animals; Bees; Glucose; Glutamic Acid; In Vitro Techniques; Male; Models, Biological; NAD; NADP; Neuroglia; Neurons; Photoreceptor Cells, Invertebrate; Proline; Retina; Signal Transduction | 1997 |
Nucleotide compositional constraints on genomes generate alanine-, glycine-, and proline-rich structures in transcription factors.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Genetic Variation; Genome; Glycine; Humans; Lizards; Mice; Molecular Sequence Data; Proline; Rats; Sequence Alignment; Sequence Homology, Amino Acid; Transcription Factors; Vertebrates; Xenopus; Zebrafish | 1997 |
An alanine to proline mutation in the 1A rod domain of the keratin 10 chain in epidermolytic hyperkeratosis.
Topics: Adolescent; Adult; Aged; Alanine; Female; Humans; Hyperkeratosis, Epidermolytic; Intermediate Filaments; Keratins; Male; Pedigree; Point Mutation; Proline; Protein Structure, Tertiary | 1997 |
Effect of mucosal amino acids on SCC and Na and Cl fluxes in the porcine small intestine.
Topics: Alanine; Amino Acids; Animals; Chloride Channels; Electric Stimulation; Glutamine; Intestinal Mucosa; Intestine, Small; Lysine; Phenylalanine; Proline; Sodium Channels; Swine | 1997 |
A short linear sequence in the pre-S domain of the large hepatitis B virus envelope protein required for virion formation.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Binding Sites; COS Cells; Gene Deletion; Genetic Complementation Test; Genome, Viral; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Molecular Sequence Data; Mutagenesis; Phenotype; Proline; Protein Precursors; Structure-Activity Relationship; Tumor Cells, Cultured; Viral Envelope Proteins; Virion; Virus Assembly | 1997 |
Introduction of a proline residue into position 31 of the loop of the dimeric 4-alpha-helical protein ROP causes a drastic destabilization.
Topics: Alanine; Bacterial Proteins; Bacteriocin Plasmids; Circular Dichroism; Escherichia coli; Helix-Loop-Helix Motifs; Proline; Protein Conformation; Protein Denaturation; RNA-Binding Proteins; Spectrometry, Fluorescence; Thermodynamics | 1997 |
Endopeptidase activities of selected Porphyromonas spp., Prevotella spp. and Fusobacterium spp. of oral and non-oral origin.
Topics: Alanine; Aminopeptidases; Bacteroides; Chymotrypsin; Coumarins; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Fluorescent Dyes; Fusobacterium; Fusobacterium necrophorum; Humans; Indicators and Reagents; Lysine; Mouth; Oligopeptides; Pancreatic Elastase; Phenylalanine; Porphyromonas; Porphyromonas gingivalis; Prevotella; Proline; Tyrosine; Virulence | 1997 |
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease.
Topics: Alanine; alpha-Synuclein; Amino Acid Sequence; Base Sequence; Female; Humans; Male; Nerve Tissue Proteins; Parkinson Disease; Pedigree; Point Mutation; Polymorphism, Single-Stranded Conformational; Proline; Synucleins | 1998 |
Alpha 1-antichymotrypsin mutations in patients with chronic obstructive pulmonary disease.
Topics: Alanine; alpha 1-Antichymotrypsin; Genotype; Humans; Lung Diseases, Obstructive; Mutation; Proline | 1998 |
Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Core Binding Factor Alpha 1 Subunit; COS Cells; Dimerization; DNA-Binding Proteins; Glutamine; Mice; Molecular Sequence Data; Neoplasm Proteins; Nuclear Localization Signals; Proline; Proto-Oncogene Proteins c-myc; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Threonine; Transcription Factor AP-2; Transcription Factors; Transcriptional Activation | 1998 |
Human immunodeficiency virus type 1 replication is modulated by host cyclophilin A expression levels.
Topics: Alanine; Gene Products, gag; Gene Products, vif; Glutamic Acid; HIV-1; Humans; Jurkat Cells; Mutagenesis, Site-Directed; Peptidylprolyl Isomerase; Proline; Tumor Cells, Cultured; vif Gene Products, Human Immunodeficiency Virus; Virion; Virus Replication | 1998 |
Molecular cloning and characterization of a novel Ste20-related protein kinase enriched in neurons and transporting epithelia.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Epithelial Cells; Immunohistochemistry; Molecular Sequence Data; Neurons; Proline; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley | 1998 |
Trans-cis isomerization of proline 22 in bovine prothrombin fragment 1: a surprising result of structural characterization.
Topics: 1-Carboxyglutamic Acid; Alanine; Amino Acid Sequence; Animals; Calcium; Cattle; Computer Simulation; Crystallography, X-Ray; Hydrogen Bonding; Molecular Sequence Data; Peptide Fragments; Phospholipids; Proline; Protein Binding; Protein Precursors; Protein Structure, Tertiary; Prothrombin; Stereoisomerism; Thermodynamics | 1998 |
Proline isomerization in bovine pancreatic ribonuclease A. 1. Unfolding conditions.
Topics: Alanine; Animals; Cattle; Guinea Pigs; Isoenzymes; Models, Molecular; Mutagenesis, Site-Directed; Proline; Protein Conformation; Protein Folding; Ribonuclease, Pancreatic; Sequence Homology, Amino Acid; Tyrosine | 1998 |
Na+ cotransport by metabolizable and nonmetabolizable amino acids stimulates a glucose-regulated insulin-secretory response.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport; Calcium; Cell Line; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Meglumine; Ouabain; Proline; Sodium; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Tetrodotoxin | 1998 |
A study of conserved in-loop and out-of-loop glycine residues in the large subunit of ribulose bisphosphate carboxylase/oxygenase by directed mutagenesis.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Blotting, Western; Conserved Sequence; Cyanobacteria; Escherichia coli; Glycine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Protein Conformation; Protein Structure, Secondary; Ribulose-Bisphosphate Carboxylase; Sequence Alignment; Structure-Activity Relationship | 1998 |
Reactivation of the totally inactive pancreatic lipase RP1 by structure-predicted point mutations.
Topics: Alanine; Animals; Dogs; Enzyme Activation; Humans; Kinetics; Lipase; Pancreas; Pancreatic Juice; Point Mutation; Proline; Protein Conformation; Structure-Activity Relationship; Valine | 1998 |
Effect of the Pro12Ala variant of the human peroxisome proliferator-activated receptor gamma 2 gene on adiposity, fat distribution, and insulin sensitivity in Japanese men.
Topics: Adipose Tissue; Adult; Aged; Alanine; Amino Acid Substitution; Blood Pressure; Body Mass Index; Fats; Genetic Variation; Humans; Insulin Resistance; Japan; Lipids; Male; Middle Aged; Nuclear Proteins; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 1998 |
Functional consequences of changing proline residues in the phenylalanine-specific permease of Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Bacterial Proteins; Cell Membrane; Conserved Sequence; Escherichia coli; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Sequence Homology, Amino Acid; Structure-Activity Relationship | 1998 |
Synthetic filaments assembled from C-terminally truncated alpha-synuclein.
Topics: Alanine; alpha-Synuclein; Amino Acid Substitution; Cloning, Molecular; Humans; Microscopy, Electron; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Open Reading Frames; Phosphoproteins; Point Mutation; Proline; Recombinant Proteins; Sequence Deletion; Synucleins; Threonine | 1998 |
Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Caseins; COS Cells; DNA; DNA-Binding Proteins; Genes, Reporter; Milk Proteins; Molecular Sequence Data; Phosphoamino Acids; Phosphorylation; Prolactin; Proline; Serine; STAT5 Transcription Factor; Structure-Activity Relationship; Trans-Activators; Transcriptional Activation | 1998 |
An electrogenic amino acid transporter in the apical membrane of cultured human bronchial epithelial cells.
Topics: Alanine; Amiloride; Amino Acid Transport Systems; Amino Acids; Arginine; Bronchi; Carrier Proteins; Cell Membrane; Cells, Cultured; Epithelial Cells; Humans; Kinetics; Lysine; Membrane Potentials; Nitric Oxide Donors; Penicillamine; Proline; S-Nitroso-N-Acetylpenicillamine | 1998 |
Proline, leucine, and alanine transport in placental microvillous membrane vesicles prepared from late gestational rats.
Topics: Alanine; Animals; Biological Transport; Female; Kinetics; Leucine; Microscopy, Electron; Microvilli; Placenta; Pregnancy; Pregnancy, Animal; Proline; Rats; Rats, Wistar | 1998 |
Engineering of S2 site of aqualysin I; alteration of P2 specificity by excluding P2 side chain.
Topics: Alanine; Bacterial Proteins; Binding Sites; Computer Simulation; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Proline; Protein Engineering; Serine Endopeptidases; Substrate Specificity | 1998 |
Ser752 mutation to Pro or Ala in the beta3 integrin subunit differentially affects the kinetics of cell spreading to von Willebrand factor and fibrinogen.
Topics: Alanine; Animals; Antigens, CD; Cell Adhesion; Cell Count; Cell Line; Cricetinae; Cytoskeleton; Fibrinogen; Humans; Image Processing, Computer-Assisted; Integrin beta3; Kinetics; Platelet Membrane Glycoproteins; Point Mutation; Proline; Serine; von Willebrand Factor | 1998 |
NMR analysis of cbEGF domains gives new insights into the structural consequences of a P1148A substitution in fibrillin-1.
Topics: Alanine; Amino Acid Substitution; Base Sequence; Cloning, Molecular; DNA Primers; Epidermal Growth Factor; Fibrillin-1; Fibrillins; Humans; Magnetic Resonance Spectroscopy; Microfilament Proteins; Proline; Protein Conformation | 1998 |
Molecular characterization of the human CRT-1 creatine transporter expressed in Xenopus oocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alanine; Amino Acid Substitution; Animals; Carrier Proteins; Chlorides; Cloning, Molecular; Creatine; Gene Expression; Humans; Ion Transport; Membrane Transport Proteins; Mutagenesis, Site-Directed; Myocardium; Oocytes; Phorbol Esters; Proline; Sodium; Xenopus | 1999 |
Functional and structural analysis of cis-proline mutants of Escherichia coli aspartate aminotransferase.
Topics: Alanine; Amino Acid Substitution; Aspartate Aminotransferases; Crystallography, X-Ray; Enzyme Activation; Escherichia coli; Guanidine; Hot Temperature; Kinetics; Ligands; Mutagenesis, Site-Directed; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Spectrophotometry; Structure-Activity Relationship | 1999 |
Pro12Ala missense mutation of the peroxisome proliferator activated receptor gamma and diabetes mellitus.
Topics: Adult; Alanine; Amino Acid Substitution; Cholesterol; Codon; Coronary Disease; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Retinopathy; Female; Gene Frequency; Genetic Variation; Humans; Hyperlipidemias; Male; Middle Aged; Mutation, Missense; Nuclear Proteins; Obesity; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Triglycerides | 1999 |
Interaction of the N-terminus of chicken skeletal essential light chain 1 with F-actin.
Topics: Actins; Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Carbodiimides; Chickens; Cross-Linking Reagents; Glutamic Acid; Lysine; Molecular Sequence Data; Muscle, Skeletal; Mutagenesis, Site-Directed; Myosin Light Chains; Peptide Fragments; Proline; Sequence Deletion | 1999 |
Conformational unfolding studies of three-disulfide mutants of bovine pancreatic ribonuclease A and the coupling of proline isomerization to disulfide redox reactions.
Topics: Alanine; Amino Acid Substitution; Animals; Cattle; Cysteine; Disulfides; Mutagenesis, Site-Directed; Oxidation-Reduction; Proline; Protein Conformation; Protein Folding; Protein Isoforms; Ribonuclease, Pancreatic; Serine; Spectrometry, Fluorescence; Spectrophotometry | 1999 |
Conformational restraints revealing bioactive beta-bend structures for halpha CGRP8-37 at the CGRP2 receptor of the rat prostatic vas deferens.
Topics: Alanine; Amino Acid Substitution; Animals; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Male; Peptide Biosynthesis; Peptide Fragments; Proline; Prostate; Protease Inhibitors; Protein Structure, Secondary; Rats; Rats, Sprague-Dawley; Receptors, Calcitonin Gene-Related Peptide; Vas Deferens | 1999 |
Functional expression of the rabbit intestinal Na+/L-proline cotransporter (IMINO system) in Xenopus laevis oocytes.
Topics: Alanine; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Cell Membrane; Cloning, Molecular; DNA, Complementary; Female; Intestinal Mucosa; Oocytes; Poly A; Proline; Rabbits; Recombinant Proteins; RNA, Messenger; Sodium; Substrate Specificity; Symporters; Xenopus laevis | 1998 |
gamma-L-glutamyl-L-DOPA inhibits Na(+)-phosphate cotransport across renal brush border membranes and increases renal excretion of phosphate.
Topics: Alanine; Animals; Biological Transport; Calcium; Carrier Proteins; Cyclic AMP; Cyclic GMP; Dihydroxyphenylalanine; Dopamine; gamma-Glutamyltransferase; Kidney Tubules, Proximal; Levodopa; Male; Microvilli; Norepinephrine; Parathyroidectomy; Phosphates; Potassium; Proline; Rats; Sodium; Sodium-Phosphate Cotransporter Proteins; Symporters; Tritium | 1999 |
The cellular kinase binding motifs (PxxP and RR) in human immunodeficiency virus type 1 Nef protein are dispensable for producer-cell-dependent enhancement of viral entry.
Topics: Alanine; Amino Acid Sequence; Arginine; Binding Sites; Cell Line, Transformed; Gene Products, nef; HeLa Cells; HIV-1; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; nef Gene Products, Human Immunodeficiency Virus; Proline; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck | 1999 |
Electric fields in active sites: substrate switching from null to strong fields in thiol- and selenol-subtilisins.
Topics: Acylation; Alanine; Amino Acid Substitution; Asparagine; Binding Sites; Crystallography, X-Ray; Cysteine; Esters; Glycine; Kinetics; Models, Molecular; Proline; Protein Conformation; Selenocysteine; Spectrum Analysis, Raman; Static Electricity; Substrate Specificity; Subtilisins | 1999 |
Glycophorin A mutation Ala65 --> Pro gives rise to a novel pair of MNS alleles ENEP (MNS39) and HAG (MNS41) and altered Wrb expression: direct evidence for GPA/band 3 interaction necessary for normal Wrb expression.
Topics: Alanine; Alleles; Anion Exchange Protein 1, Erythrocyte; Antigens; Coombs Test; Erythrocyte Membrane; Glycophorins; Humans; Male; Middle Aged; MNSs Blood-Group System; Mutation; Proline; Protein Structure, Secondary; Sequence Analysis, DNA | 1999 |
The PPARgamma2 amino acid polymorphism Pro 12 Ala is prevalent in offspring of Type II diabetic patients and is associated to increased insulin sensitivity in a subgroup of obese subjects.
Topics: Adult; Alanine; Amino Acid Substitution; Codon; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Male; Mutation; Obesity; Polymorphism, Genetic; Proline; Quantitative Trait, Heritable; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 1999 |
Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma2 is not associated with type 2 diabetes.
Topics: Adipose Tissue; Adult; Aged; Alanine; Case-Control Studies; Diabetes Mellitus, Type 2; Humans; Male; Middle Aged; Odds Ratio; Point Mutation; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 1999 |
Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; CD28 Antigens; Enzyme Activation; Gene Expression Regulation; Genes, fos; Humans; Jurkat Cells; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Mice, Inbred C57BL; Molecular Sequence Data; Peptides; Proline; Protein Binding; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Retroviridae; src Homology Domains; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1999 |
The molecular basis for the B(A) allele: an amino acid alteration in the human histoblood group B alpha-(1,3)-galactosyltransferase increases its intrinsic alpha-(1,3)-N-acetylgalactosaminyltransferase activity.
Topics: ABO Blood-Group System; Alanine; Alleles; Female; Galactosyltransferases; Heterozygote; Humans; Male; N-Acetylglucosaminyltransferases; Pedigree; Point Mutation; Polymerase Chain Reaction; Proline | 1999 |
SH2-kinase linker mutations release Hck tyrosine kinase and transforming activities in Rat-2 fibroblasts.
Topics: Alanine; Amino Acid Substitution; Animals; Fibroblasts; Gene Products, nef; Humans; Mutation; Phosphorylation; Proline; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Rats; src Homology Domains; Substrate Specificity | 1999 |
Hb Brie Comte Robert [beta36(C2)Pro-->Ala]: a new hemoglobin variant with high oxygen affinity and marked hydrophobic properties.
Topics: Adult; Alanine; France; Hematologic Tests; Hemoglobins, Abnormal; Humans; Oxygen; Point Mutation; Polycythemia; Proline; Solubility; White People | 1999 |
Hepatocyte nuclear factor-6: associations between genetic variability and type II diabetes and between genetic variability and estimates of insulin secretion.
Topics: Adult; Alanine; Alleles; Amino Acid Substitution; Chromosome Mapping; Chromosomes, Human, Pair 15; Cloning, Molecular; Diabetes Mellitus, Type 2; Exons; Female; Gene Frequency; Genetic Variation; Hepatocyte Nuclear Factor 6; Homeodomain Proteins; Humans; Insulin; Insulin Secretion; Introns; Male; Middle Aged; Mutation, Missense; Polymorphism, Single-Stranded Conformational; Proline; Registries; Trans-Activators; White People | 1999 |
Effects of mutations of the active site arginine residues in 4-oxalocrotonate tautomerase on the pKa values of active site residues and on the pH dependence of catalysis.
Topics: Alanine; Arginine; Binding Sites; Catalysis; Glutamine; Hydrogen-Ion Concentration; Isomerases; Kinetics; Mutagenesis, Site-Directed; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Proline; Pseudomonas putida; Substrate Specificity; Titrimetry | 1999 |
Activation of recombinant bovine matrix metalloproteinase-20 and its hydrolysis of two amelogenin oligopeptides.
Topics: Alanine; Ameloblasts; Amelogenin; Amino Acids; Animals; Calcium; Cattle; Chromatography, Affinity; Chromatography, Ion Exchange; Dental Enamel Proteins; Dialysis; Enzyme Activation; Escherichia coli; Gene Expression Regulation, Enzymologic; Genetic Vectors; Hydrolysis; Leucine; Mass Spectrometry; Matrix Metalloproteinase 20; Matrix Metalloproteinases; Proline; Recombinant Proteins; Tryptophan; Zinc | 1999 |
Substitutions in a flexible loop of horse liver alcohol dehydrogenase hinder the conformational change and unmask hydrogen transfer.
Topics: Alanine; Alcohol Dehydrogenase; Amino Acid Substitution; Animals; Crystallography, X-Ray; Electron Transport; Enzyme Activation; Glycine; Horses; Hydrogen; Kinetics; Liver; Mutagenesis, Site-Directed; Proline; Protein Conformation; Substrate Specificity; Threonine | 1999 |
Glucose and amino acid metabolism in Caco-2 cells maintained in a serum- and hormone-free medium.
Topics: Alanine; Amino Acids; Caco-2 Cells; Culture Media, Serum-Free; Epidermal Growth Factor; Glucose; Glutamine; Hormones; Humans; Proline | 1999 |
Expression of a reflex biting/snapping response to amino acids prior to first exogenous feeding in salmonid alevins.
Topics: Alanine; Amino Acids; Animals; Deglutition; Larva; Oncorhynchus mykiss; Pharynx; Photic Stimulation; Predatory Behavior; Proline; Reflex; Smell; Swimming; Taste; Trout | 1999 |
Decisive structural determinants for the interaction of proline derivatives with the intestinal H+/peptide symporter.
Topics: Alanine; Dose-Response Relationship, Drug; Electrophoresis, Capillary; Humans; Kinetics; Models, Chemical; Peptides; Proline; Protein Binding; Protein Conformation; Protein Transport; Time Factors; Tumor Cells, Cultured | 1999 |
The occurrence of polymorphism of mannose 6-phosphate/insulin-like growth factor 2 receptor gene in laboratory and wild rats.
Topics: Alanine; Animals; Animals, Laboratory; Animals, Wild; Base Sequence; Exons; Male; Mannosephosphates; Methyldimethylaminoazobenzene; Molecular Sequence Data; Polymorphism, Genetic; Proline; Rats; Rats, Inbred Strains; Receptors, Somatomedin | 1999 |
Thermodynamic origin of cis/trans isomers of a proline-containing beta-turn model dipeptide in aqueous solution: a combined variable temperature 1H-NMR, two-dimensional 1H,1H gradient enhanced nuclear Overhauser effect spectroscopy (NOESY), one-dimensiona
Topics: Alanine; Dipeptides; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Proline; Protein Conformation; Protein Structure, Secondary; Solutions; Stereoisomerism; Temperature; Thermodynamics; Water | 2000 |
Conformation, independent of charge, in the R domain affects cystic fibrosis transmembrane conductance regulator channel openings.
Topics: Alanine; Amino Acid Substitution; Cell Line; Conserved Sequence; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Ion Channel Gating; Kinetics; Membrane Potentials; Mutagenesis, Site-Directed; Peptidylprolyl Isomerase; Phosphorylation; Probability; Proline; Protein Conformation; Recombinant Proteins; Transfection | 2000 |
Bioactive beta-bend structures for the antagonist halpha CGRP(8 - 37) at the CGRP(1) receptor of the rat pulmonary artery.
Topics: Alanine; Amino Acid Substitution; Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Glutamic Acid; Glycine; In Vitro Techniques; Male; Molecular Conformation; Muscle Relaxation; Muscle, Smooth, Vascular; Peptide Fragments; Proline; Pulmonary Artery; Rats; Rats, Sprague-Dawley | 2000 |
Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid.
Topics: Alanine; alpha-Synuclein; Amino Acid Sequence; Amyloid; Benzothiazoles; Binding Sites; Brain; Circular Dichroism; Congo Red; Endopeptidases; Humans; Hydrolysis; Immunohistochemistry; Lewy Bodies; Microscopy, Atomic Force; Microscopy, Polarization; Molecular Sequence Data; Mutation, Missense; Nerve Tissue Proteins; Parkinson Disease; Postmortem Changes; Proline; Protein Structure, Secondary; Recombinant Proteins; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Synucleins; Thiazoles; Threonine | 2000 |
Sample optimization and identification of signal patterns of amino acid side chains in 2D RFDR spectra of the alpha-spectrin SH3 domain.
Topics: Alanine; Amino Acids; Carbon Isotopes; Chemical Precipitation; Isoleucine; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Proline; Protein Conformation; Serine; Spectrin; src Homology Domains; Threonine; Valine | 2000 |
The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes.
Topics: Adult; Aged; Alanine; Diabetes Mellitus, Type 2; Female; Genotype; Glutamine; Humans; Male; Middle Aged; Mutation; Obesity, Morbid; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2000 |
Calcitonin gene-related peptide regulates amino acid absorption across rat jejunum.
Topics: Alanine; Animals; Calcitonin Gene-Related Peptide; Capsaicin; In Vitro Techniques; Injections, Intravenous; Intestinal Absorption; Jejunum; Proline; Rats; Rats, Sprague-Dawley | 2000 |
Splanchnic and leg exchange of amino acids and ammonia in acute liver failure.
Topics: Adult; Alanine; Amino Acids; Ammonia; Blood Urea Nitrogen; Citrulline; Female; Femoral Artery; Femoral Vein; Fibrosis; Glutamine; Humans; Leg; Liver Failure, Acute; Male; Middle Aged; Predictive Value of Tests; Proline; Splanchnic Circulation; Urea | 2000 |
Significance of Pro12Ala mutation in peroxisome proliferator-activated receptor-gamma2 in Korean diabetic and obese subjects.
Topics: Alanine; Amino Acid Substitution; Asian People; Body Mass Index; Diabetes Mellitus; Female; Genotype; Glucose Intolerance; Humans; Korea; Male; Middle Aged; Nuclear Proteins; Obesity; Point Mutation; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2000 |
Association between alpha-1-antichymotrypsin polymorphism and susceptibility to chronic obstructive pulmonary disease.
Topics: Adult; Alanine; Alleles; alpha 1-Antichymotrypsin; Amino Acid Substitution; Genetic Predisposition to Disease; Genotype; Heterozygote; Homozygote; Humans; Lung Diseases, Obstructive; Male; Polymorphism, Genetic; Proline; Protein Sorting Signals | 2000 |
Chiral discrimination of N-carbazole-carbonyl derivatives of alpha-amino acids with a short linear alkyl side chain by bovine serum albumin.
Topics: Alanine; Alkylation; Amino Acids; Binding Sites; Carbazoles; Chromatography, High Pressure Liquid; Dansyl Compounds; Proline; Protein Binding; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stereoisomerism; Valine | 2000 |
A cis-proline to alanine mutant of E. coli aspartate transcarbamoylase: kinetic studies and three-dimensional crystal structures.
Topics: Alanine; Aspartate Carbamoyltransferase; Crystallography, X-Ray; Escherichia coli; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Proline | 2000 |
Mutations in the hinge of a dynamic loop broadly influence functional properties of fructose-1,6-bisphosphatase.
Topics: Adenosine Monophosphate; Alanine; Allosteric Regulation; Animals; Catalytic Domain; Fructose-Bisphosphatase; Kinetics; Lysine; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Proline; Swine | 2000 |
Monomeric sarcosine oxidase: 2. Kinetic studies with sarcosine, alternate substrates, and a substrate analogue.
Topics: Alanine; Bacillus; Binding, Competitive; Catalysis; Enzyme Inhibitors; Kinetics; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Proline; Sarcosine; Sarcosine Oxidase; Substrate Specificity; Thioglycolates | 2000 |
DNA recognition by the methyl-CpG binding domain of MeCP2.
Topics: Alanine; Amino Acid Substitution; Arginine; Aspartic Acid; Chromosomal Proteins, Non-Histone; CpG Islands; DNA; DNA-Binding Proteins; Electrophoresis; Glycine; Humans; Methyl-CpG-Binding Protein 2; Mutagenesis, Site-Directed; Mutation, Missense; Proline; Protein Conformation; Protein Structure, Tertiary; Repressor Proteins; Rett Syndrome | 2001 |
Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling.
Topics: Alanine; Amino Acid Substitution; Cells, Cultured; Crystallography, X-Ray; Cytotoxicity Tests, Immunologic; Gene Products, tax; Glycine; HLA-A2 Antigen; Humans; Ligands; Peptides; Proline; Protein Binding; Protein Folding; Receptors, Antigen, T-Cell, alpha-beta; Sarcosine; Signal Transduction; T-Lymphocytes, Cytotoxic; Thermodynamics; Ultracentrifugation; Water | 2000 |
Opioid pseudopeptides containing heteroaromatic or heteroaliphatic nuclei.
Topics: Alanine; Benzimidazoles; Binding Sites; Carbolines; Carboxylic Acids; Dipeptides; Isoquinolines; Kinetics; Ligands; Peptides; Proline; Propionates; Protein Conformation; Receptors, Opioid, delta; Receptors, Opioid, mu; Serine; Tetrahydroisoquinolines; Tyrosine | 2000 |
Sequence requirements for the N-methyl-D-aspartate receptor antagonist activity of conantokin-R.
Topics: 1-Carboxyglutamic Acid; Alanine; Animals; Arginine; Cations; Circular Dichroism; Conotoxins; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Inhibitory Concentration 50; Intercellular Signaling Peptides and Proteins; Leucine; Lysine; Magnetic Resonance Spectroscopy; Methionine; Mice; Mollusk Venoms; Peptides; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Temperature | 2001 |
The peroxisomal membrane protein Pex13p shows a novel mode of SH3 interaction.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Binding, Competitive; Cell Division; Dose-Response Relationship, Drug; Escherichia coli; Glutathione Transferase; Ligands; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peroxisome-Targeting Signal 1 Receptor; Peroxisomes; Proline; Protein Binding; Protein Structure, Secondary; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; src Homology Domains; Suppression, Genetic; Two-Hybrid System Techniques | 2000 |
Amino acid residues conferring herbicide tolerance in tobacco acetolactate synthase.
Topics: Acetolactate Synthase; Alanine; Amino Acid Substitution; Drug Tolerance; Enzyme Induction; Herbicides; Imidazoles; Kinetics; Mutagenesis, Site-Directed; Nicotiana; Plants, Toxic; Proline; Pyrimidines; Recombinant Proteins; Serine; Structure-Activity Relationship; Sulfonylurea Compounds; Triazoles | 2000 |
Novel mutations in the GALK1 gene in patients with galactokinase deficiency.
Topics: Adolescent; Adult; Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Child, Preschool; Cysteine; Female; Galactokinase; Galactosemias; Humans; Male; Methionine; Mice; Molecular Sequence Data; Mutation; Proline; Sequence Deletion; Threonine | 2001 |
Effect of the peroxisome proliferator-activated receptor-gamma 2 pro(12)ala variant on obesity, glucose homeostasis, and blood pressure in members of familial type 2 diabetic kindreds.
Topics: Alanine; Amino Acid Substitution; Blood Glucose; Blood Pressure; Body Mass Index; Chromosomes, Human, Pair 3; Diabetes Mellitus; Diabetes Mellitus, Type 2; Family; Gene Frequency; Genetic Variation; Glucose Tolerance Test; Humans; Leptin; Microbodies; Middle Aged; Nuclear Family; Obesity; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors; White People | 2001 |
The role of a proline-induced broken-helix motif in alpha-helix 2 of Bacillus thuringiensis delta-endotoxins.
Topics: Alanine; Amino Acid Motifs; Animals; Bacillus thuringiensis; Bacillus thuringiensis Toxins; Bacterial Proteins; Bacterial Toxins; Cell Membrane; Chromatography, High Pressure Liquid; Electrophysiology; Endotoxins; Glycine; Hemolysin Proteins; Manduca; Microvilli; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Proline; Protein Structure, Secondary; Serine; Temperature; Time Factors | 2001 |
Different conformations of nascent polypeptides during translocation across the ER membrane.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Dogs; Endoplasmic Reticulum; Glycosylation; Intracellular Membranes; Leucine; Membrane Transport Proteins; Microsomes; Molecular Sequence Data; Peptide Mapping; Proline; Protein Conformation; Protein Transport; Ribosomes; Signal Recognition Particle; Valine | 2000 |
Integumental amino acid uptake in a carnivorous predator mollusc (Sepia officinalis, Cephalopoda).
Topics: Alanine; Amino Acids; Animals; Biological Transport; Cations; Immunohistochemistry; Leucine; Lysine; Microscopy, Electron; Microscopy, Fluorescence; Microvilli; Mollusca; Proline; Sodium; Time Factors | 2000 |
A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associated with combined hyperlipidaemia in obesity.
Topics: Aging; Alanine; Alleles; Amino Acid Substitution; Anthropometry; Australia; Blood Pressure; Cholesterol, HDL; Diabetes Mellitus; Female; Genetic Predisposition to Disease; Genotype; Humans; Hyperlipidemias; Male; Middle Aged; Obesity; Odds Ratio; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Sex Characteristics; Smoking; Thinness; Transcription Factors; Triglycerides; White People | 2001 |
Antibodies recognizing CD24 LAP epitope on human T cells enhance CD28 and IL-2 T cell proliferation.
Topics: Adjuvants, Immunologic; Alanine; Antibodies, Monoclonal; Antigens, CD; CD24 Antigen; CD28 Antigens; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Membrane; Cells, Cultured; Epitopes, T-Lymphocyte; Humans; Interleukin-2; Interphase; Leucine; Leukocytes, Mononuclear; Lymphocyte Activation; Membrane Glycoproteins; Oligopeptides; Proline; T-Lymphocyte Subsets | 2001 |
The structural basis for the perturbed pKa of the catalytic base in 4-oxalocrotonate tautomerase: kinetic and structural effects of mutations of Phe-50.
Topics: Alanine; Amino Acid Sequence; Catalysis; Circular Dichroism; Escherichia coli; Hydrogen-Ion Concentration; Isomerases; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Polymerase Chain Reaction; Proline; Recombinant Proteins; Structure-Activity Relationship; Titrimetry; Tyrosine | 2001 |
Structure of Ala(20) --> Pro/Pro(64) --> Ala substituted subunit c of Escherichia coli ATP synthase in which the essential proline is switched between transmembrane helices.
Topics: Alanine; Amino Acid Sequence; Escherichia coli; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Proline; Protein Conformation; Proton-Translocating ATPases | 2001 |
Effect of experimental elevation of free fatty acids on insulin secretion and insulin sensitivity in healthy carriers of the Pro12Ala polymorphism of the peroxisome proliferator--activated receptor-gamma2 gene.
Topics: Alanine; Amino Acid Substitution; Blood Glucose; C-Peptide; DNA-Binding Proteins; Fasting; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Heparin; Heterozygote; Humans; Infusions, Intravenous; Insulin; Insulin Secretion; Male; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2001 |
Familial parkinsonism with synuclein pathology: clinical and PET studies of A30P mutation carriers.
Topics: Aged; Alanine; alpha-Synuclein; Amino Acid Sequence; Apolipoproteins E; Brain; DNA Mutational Analysis; Female; Genotype; Germany; Humans; Male; Middle Aged; Mutation; Nerve Tissue Proteins; Neuropsychological Tests; Parkinsonian Disorders; Pedigree; Proline; Synucleins; Thiolester Hydrolases; Tomography, Emission-Computed; Ubiquitin Thiolesterase | 2001 |
Isolation and characterisation of dipeptidyl peptidase IV from Prevotella loescheii ATCC 15930.
Topics: Alanine; Cadmium; Chromatography; Chromatography, Gel; Chromatography, High Pressure Liquid; Cobalt; Coumarins; Dipeptides; Dipeptidyl Peptidase 4; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Isoelectric Point; Isoflurophate; Mercaptoethanol; Mercury; Molecular Weight; Prevotella; Proline; Protease Inhibitors; Serine Proteinase Inhibitors; Zinc | 2001 |
Identification and characterization of a lysosomal transporter for small neutral amino acids.
Topics: Alanine; Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Amino Acids, Neutral; Animals; Brain; Caenorhabditis elegans; Carrier Proteins; Cell Line; Cerebral Cortex; Cloning, Molecular; Drosophila melanogaster; Evolution, Molecular; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Lysosomes; Male; Molecular Sequence Data; Phylogeny; Proline; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Alignment; Sequence Homology, Amino Acid; Symporters; Transfection | 2001 |
Proline-induced hinges in transmembrane helices: possible roles in ion channel gating.
Topics: Alamethicin; Alanine; Amino Acid Motifs; Amino Acid Sequence; Chloride Channels; Computer Simulation; Humans; Ion Channel Gating; Lipid Bilayers; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Potassium Channels; Proline; Protein Structure, Secondary; Thermodynamics | 2001 |
Species-specific differences in amino acid editing by class II prolyl-tRNA synthetase.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Amino Acyl-tRNA Synthetases; Escherichia coli; Humans; Methanococcus; Molecular Sequence Data; Proline; RNA Editing; RNA, Transfer, Amino Acyl; Species Specificity | 2001 |
Positional importance of Pro53 adjacent to the Arg49-Gly50-Asp51 sequence of rhodostomin in binding to integrin alphaIIbbeta3.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Blood Platelets; Cloning, Molecular; Escherichia coli; Glutathione Transferase; Humans; Kinetics; Luminescent Measurements; Molecular Sequence Data; Mutagenesis, Insertional; Oligopeptides; Peptides; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Proline; Recombinant Fusion Proteins; Sequence Alignment; Thrombin | 2001 |
Effect of mutation of proline 93 on redox unfolding/folding of bovine pancreatic ribonuclease A.
Topics: Alanine; Amino Acid Substitution; Animals; Cattle; Chromatography, Ion Exchange; Disulfides; Kinetics; Oxidation-Reduction; Point Mutation; Proline; Protein Conformation; Protein Folding; Ribonuclease, Pancreatic | 2001 |
Effect of the Pro12Ala polymorphism of the PPAR-gamma2 gene on long-term weight change in Finnish non-diabetic subjects.
Topics: Alanine; Alternative Splicing; Amino Acid Substitution; Codon; DNA-Binding Proteins; Female; Finland; Genotype; Humans; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Proline; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Reference Values; Software; Transcription Factors; Weight Gain; Weight Loss | 2001 |
Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) gene in relation to insulin sensitivity among glucose tolerant caucasians.
Topics: Aged; Alanine; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin Resistance; Male; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Proline; Receptors, Cytoplasmic and Nuclear; Sweden; Transcription Factors | 2001 |
Sibling-based association study of the PPARgamma2 Pro12Ala polymorphism and metabolic variables in Chinese and Japanese hypertension families: a SAPPHIRe study. Stanford Asian-Pacific Program in Hypertension and Insulin Resistance.
Topics: Adult; Age Factors; Aged; Alanine; Alleles; Blood Glucose; China; Family Health; Female; Genotype; Glucose Tolerance Test; Homozygote; Humans; Hypertension; Insulin Resistance; Japan; Male; Middle Aged; Obesity; Phenotype; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Regression Analysis; Sex Factors; Time Factors; Transcription Factors | 2001 |
Increased proteolytic resistance of ribonuclease A by protein engineering.
Topics: Alanine; Animals; Circular Dichroism; Endopeptidase K; Enzyme Stability; Mutagenesis, Site-Directed; Mutation; Pancreatic Elastase; Proline; Protein Conformation; Protein Engineering; Ribonuclease, Pancreatic; Rosaniline Dyes; Spectrometry, Fluorescence; Subtilisins; Swine; Thermodynamics | 2001 |
Competing modes of self-association in the regulatory domains of Bruton's tyrosine kinase: intramolecular contact versus asymmetric homodimerization.
Topics: Agammaglobulinaemia Tyrosine Kinase; Alanine; Amino Acid Sequence; Dimerization; Dose-Response Relationship, Drug; Humans; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; Phosphorylation; Proline; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Sequence Homology, Amino Acid; src Homology Domains | 2002 |
Relation between the flexibility of the WPD loop and the activity of the catalytic domain of protein tyrosine phosphatase SHP-1.
Topics: Alanine; Catalytic Domain; Conserved Sequence; Enzyme Activation; Intracellular Signaling Peptides and Proteins; Kinetics; Models, Molecular; Mutation; Pliability; Proline; Protein Conformation; Protein Structure, Secondary; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2001 |
Effects of replacement of prolines with alanines on the catalytic activity and thermostability of inorganic pyrophosphatase from thermophilic bacterium PS-3.
Topics: Alanine; Amino Acid Substitution; Catalysis; Circular Dichroism; Enzyme Activation; Enzyme Stability; Escherichia coli; Hot Temperature; Inorganic Pyrophosphatase; Point Mutation; Proline; Pyrophosphatases; Thermus thermophilus | 2002 |
Differing substrate specificities of members of the DYRK family of arginine-directed protein kinases.
Topics: Alanine; Animals; Arginine; Dyrk Kinases; Eukaryotic Initiation Factor-2B; Peptides; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Serine; Substrate Specificity | 2002 |
Differential effect of brefeldin A on the palmitoylation of surfactant protein C proprotein mutants.
Topics: Alanine; Animals; Antioxidants; Brefeldin A; Cell Membrane; Cell Nucleus; CHO Cells; Cricetinae; Cysteine; Immunohistochemistry; Kinetics; Leucine; Masoprocol; Monensin; Mutation; Nocodazole; Palmitic Acid; Palmitic Acids; Peptides; Proline; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Pulmonary Surfactants; Recombinant Proteins; Transfection | 2002 |
An N-terminal arginine-rich cluster and a proline-alanine-threonine repeat region determine the cellular localization of the herpes simplex virus type 1 ICP34.5 protein and its ligand, protein phosphatase 1.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Base Sequence; Cell Compartmentation; Chlorocebus aethiops; DNA Primers; Fluorescent Antibody Technique, Indirect; Ligands; Molecular Sequence Data; Phosphoprotein Phosphatases; Proline; Protein Phosphatase 1; Recombinant Proteins; Repetitive Sequences, Amino Acid; Subcellular Fractions; Threonine; Vero Cells; Viral Proteins | 2002 |
Heat labile ribonuclease HI from a psychrotrophic bacterium: gene cloning, characterization and site-directed mutagenesis.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cloning, Molecular; Enzyme Stability; Escherichia coli; Genetic Complementation Test; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Proline; Ribonuclease H; Sequence Analysis, Protein; Shewanella; Substrate Specificity; Temperature | 2001 |
Characterization of the aryl hydrocarbon receptor repressor gene and association of its Pro185Ala polymorphism with micropenis.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Basic Helix-Loop-Helix Transcription Factors; Humans; Male; Mice; Penis; Polymorphism, Genetic; Proline; Receptors, Aryl Hydrocarbon; Repressor Proteins | 2002 |
Reduced lipolysis as possible cause for greater weight gain in subjects with the Pro12Ala polymorphism in PPARgamma2?
Topics: Adult; Alanine; Amino Acid Substitution; Blood Glucose; Body Mass Index; Fatty Acids, Nonesterified; Female; Humans; Insulin; Lipolysis; Male; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Weight Gain | 2002 |
Free amino acids in claw muscle and haemolymph from Australian freshwater crayfish at different stages of the moult cycle.
Topics: Alanine; Amino Acids; Animals; Astacoidea; Australia; Extremities; Fresh Water; Glutamine; Hemolymph; Molting; Muscle Fibers, Skeletal; Muscles; Proline | 2002 |
The proline 12 alanine substitution in the peroxisome proliferator--activated receptor-gamma2 gene is associated with lower lipoprotein lipase activity in vivo.
Topics: Aged; Alanine; Alleles; Coronary Disease; Deoxyribonuclease HindIII; Deoxyribonucleases, Type II Site-Specific; Humans; Lipoprotein Lipase; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Proline; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Response Elements; Structure-Activity Relationship; Transcription Factors | 2002 |
PPARgamma2 pro12Ala polymorphism and insulin resistance in Japanese hypertensive patients.
Topics: Adult; Alanine; Alleles; Amino Acid Substitution; Arginine; Asian People; Gene Frequency; Genotype; Humans; Hypertension; Insulin Resistance; Japan; Male; Middle Aged; Polymorphism, Genetic; Proline; Receptors, Adrenergic, beta; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tryptophan | 2002 |
Effect of multivalency on the performance of enantioselective separation media for chiral HPLC prepared by linking multiple selectors to a porous polymer support via aliphatic dendrons.
Topics: Alanine; Amino Acids; Catalysis; Chemistry, Organic; Chromatography, High Pressure Liquid; Leucine; Ligands; Molecular Structure; Polymers; Polymethacrylic Acids; Proline; Stereoisomerism; Time Factors | 2002 |
Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma2 (PPARgamma2) is associated with higher levels of total cholesterol and LDL-cholesterol in male caucasian type 2 diabetes patients.
Topics: Aged; Alanine; Alleles; Cholesterol; Cholesterol, LDL; Cohort Studies; Diabetes Mellitus, Type 2; Female; Heterozygote; Homozygote; Humans; Hypercholesterolemia; Logistic Models; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Proline; Receptors, Cytoplasmic and Nuclear; Sex Characteristics; Transcription Factors | 2002 |
Scanning mutagenesis of a Janus-faced atracotoxin reveals a bipartite surface patch that is essential for neurotoxic function.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Base Sequence; Cell Line; Circular Dichroism; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutathione Transferase; Insecta; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Point Mutation; Potassium; Proline; Protein Folding; Recombinant Proteins; Sequence Homology, Amino Acid; Spider Venoms; Tyrosine; Ultraviolet Rays | 2002 |
Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters.
Topics: Alanine; Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Amino Acids; Animals; Biological Transport; Blotting, Northern; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Electrophysiology; Epithelial Cells; Glycine; Green Fluorescent Proteins; HeLa Cells; Humans; Hydrogen-Ion Concentration; Ions; Kinetics; Luminescent Proteins; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Proline; Protein Binding; Protein Structure, Tertiary; RNA, Complementary; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Substrate Specificity; Sulfate Transporters; Symporters; Tissue Distribution; Transfection; Xenopus laevis | 2002 |
Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure.
Topics: Alanine; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Specificity; Antigens, CD20; Cell Membrane; Epitope Mapping; Epitopes; Humans; Membrane Microdomains; Mice; Molecular Sequence Data; Mutagenesis; Proline; Protein Structure, Quaternary; Tumor Cells, Cultured | 2002 |
Disruption of the alpha5 helix of transducin impairs rhodopsin-catalyzed nucleotide exchange.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Cattle; Gene Deletion; Molecular Sequence Data; Mutagenesis; Mutagenesis, Insertional; Nucleotides; Proline; Protein Structure, Secondary; Rhodopsin; Transducin | 2002 |
Functional role of the prokaryotic proline-tRNA synthetase insertion domain in amino acid editing.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Binding Sites; Molecular Sequence Data; Mutagenesis, Insertional; Prokaryotic Cells; Proline; Protein Structure, Tertiary; RNA Editing; Sequence Alignment | 2002 |
[Association of Pro12Ala variant in peroxisome proliferator-activated receptor-gamma2 gene with type 2 diabetes mellitus].
Topics: Adult; Alanine; Alleles; Amino Acid Substitution; Blood Glucose; Body Constitution; Body Mass Index; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; Humans; Insulin; Male; Middle Aged; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Triglycerides | 2002 |
Hsc62, Hsc56, and GrpE, the third Hsp70 chaperone system of Escherichia coli.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Bacterial Proteins; Cloning, Molecular; Dose-Response Relationship, Drug; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Heat-Shock Proteins; Histidine; HSP70 Heat-Shock Proteins; Molecular Chaperones; Molecular Sequence Data; Mutation; Plasmids; Proline; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Time Factors | 2002 |
Key motif to gain selectivity at the neuropeptide Y5-receptor: structure and dynamics of micelle-bound [Ala31, Pro32]-NPY.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Circular Dichroism; Crystallography, X-Ray; Deuterium; Micelles; Molecular Sequence Data; Mutagenesis, Site-Directed; Neuropeptide Y; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphorylcholine; Proline; Protein Conformation; Protein Structure, Secondary; Protons; Rats; Receptors, Neuropeptide Y; Spin Labels; Thermodynamics | 2002 |
Is a Pro12Ala polymorphism of the PPARgamma2 gene related to obesity and type 2 diabetes mellitus in the Czech population?
Topics: Adult; Alanine; Case-Control Studies; Czechoslovakia; Diabetes Mellitus, Type 2; Female; Genetics, Population; Genotype; Humans; Male; Middle Aged; Obesity; Phenotype; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2002 |
The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on insulin sensitivity and insulin metabolism interact with size at birth.
Topics: Alanine; Amino Acid Substitution; Birth Weight; Diabetes Mellitus, Type 2; Female; Humans; Infant, Newborn; Insulin; Male; Middle Aged; Polymorphism, Single Nucleotide; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2002 |
Peroxisome proliferator-activated receptor-gamma2 polymorphism Pro12Ala is associated with nephropathy in type 2 diabetes: The Berlin Diabetes Mellitus (BeDiaM) Study.
Topics: Alanine; Amino Acid Substitution; Body Mass Index; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; DNA-Binding Proteins; Female; Genotype; Germany; Humans; Kidney Failure, Chronic; Male; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors; White People | 2002 |
Comment: studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Danish MONICA cohort: homozygosity of the Ala allele confers a decreased risk of the insulin resistance syndrome.
Topics: Adult; Aged; Alanine; Cohort Studies; Denmark; Disease Susceptibility; Female; Gene Frequency; Genetic Predisposition to Disease; Homozygote; Humans; Male; Metabolic Syndrome; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; Proline; Receptors, Cytoplasmic and Nuclear; Risk Factors; Transcription Factors | 2002 |
A conserved cis peptide bond is necessary for the activity of Bowman-Birk inhibitor protein.
Topics: Alanine; Amino Acid Sequence; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Proline; Protein Conformation; Structure-Activity Relationship; Substrate Specificity; Thermodynamics; Trypsin; Trypsin Inhibitor, Bowman-Birk Soybean | 2002 |
Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma is associated with increased leptin levels in women with type-2 diabetes mellitus.
Topics: Aged; Alanine; Alleles; Antigens, CD; Body Mass Index; Cytokines; Diabetes Mellitus, Type 2; Female; Gene Frequency; Heterozygote; Humans; Leptin; Linear Models; Male; Middle Aged; Mutation; Obesity; Proline; Receptors, Cytoplasmic and Nuclear; Receptors, Leptin; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Sex Characteristics; Transcription Factors | 2002 |
Effects of epidermal growth factor on placental amino acids uptake in pregnant rats.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Epidermal Growth Factor; Female; Leucine; Microvilli; Placenta; Pregnancy; Proline; Random Allocation; Rats; Rats, Wistar; Sodium; Up-Regulation | 2002 |
Assessment of enamelysin (MMP-20) selectivity to three peptide bonds on amelogenin sequence.
Topics: Alanine; Amelogenesis; Amelogenin; Amino Acid Sequence; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Dental Enamel; Dental Enamel Proteins; Hydrolysis; Leucine; Matrix Metalloproteinase 20; Matrix Metalloproteinases; Methionine; Peptide Mapping; Proline; Protein Folding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Proteins; Serine; Statistics as Topic; Substrate Specificity; Swine; Time Factors; Tooth Calcification; Tryptophan | 2002 |
Follicle-stimulating hormone interacts with exoloop 3 of the receptor.
Topics: Alanine; Amino Acid Sequence; Animals; Binding, Competitive; Cell Line; Cyclic AMP; DNA Mutational Analysis; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Humans; Inositol Phosphates; Kinetics; Leucine; Lysine; Models, Molecular; Molecular Sequence Data; Proline; Protein Binding; Protein Structure, Tertiary; Receptors, FSH; Signal Transduction; Software | 2002 |
Amino acid content of cell cultures infected with Cowdria ruminantium propagated in a protein-free medium.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Bacteriological Techniques; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media, Serum-Free; Ehrlichia ruminantium; Glutamine; Glycine; Heartwater Disease; Proline; Ruminants; Serine; Tryptophan | 2002 |
PPAR(gamma)2 gene Pro12Ala polymorphism may influence serum level of an adipocyte-derived protein, adiponectin, in the Japanese population.
Topics: Adiponectin; Adult; Alanine; Alleles; Asian People; Blood Glucose; Body Mass Index; Female; Humans; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Japan; Lipids; Male; Middle Aged; Polymorphism, Genetic; Proline; Proteins; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2002 |
Haplotype analysis of the PPARgamma Pro12Ala and C1431T variants reveals opposing associations with body weight.
Topics: Adult; Alanine; Amino Acid Substitution; Body Mass Index; Body Weight; Cytosine; Diabetes Mellitus, Type 2; Exercise; Female; Genetic Carrier Screening; Genetic Testing; Genetic Variation; Genotype; Haplotypes; Humans; Linkage Disequilibrium; Male; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Regression Analysis; Thymine; Transcription Factors | 2002 |
A TATA binding protein mutant with increased affinity for DNA directs transcription from a reversed TATA sequence in vivo.
Topics: Adenosine Triphosphatases; Alanine; Binding Sites; Crystallography, X-Ray; DNA; DNA Footprinting; DNA Helicases; Gene Expression Regulation, Fungal; Genes, Reporter; Models, Molecular; Mutation; Phenotype; Proline; Protein Structure, Tertiary; Recombinant Fusion Proteins; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; TATA Box; TATA-Binding Protein Associated Factors; TATA-Box Binding Protein; Trans-Activators; Transcription, Genetic | 2002 |
The founder mutation MSH2*1906G-->C is an important cause of hereditary nonpolyposis colorectal cancer in the Ashkenazi Jewish population.
Topics: Alanine; Case-Control Studies; Chromosomes, Human, Pair 2; Colorectal Neoplasms, Hereditary Nonpolyposis; Crystallography, X-Ray; DNA-Binding Proteins; Female; Founder Effect; Gene Frequency; Genetic Predisposition to Disease; Haplotypes; Heterozygote; Humans; Israel; Jews; Male; Microsatellite Repeats; Mutation, Missense; MutS Homolog 2 Protein; Neoplasms; Pedigree; Point Mutation; Polymorphism, Genetic; Proline; Protein Conformation; Proto-Oncogene Proteins | 2002 |
Dopamine efflux via wild-type and mutant dopamine transporters: alanine substitution for proline-572 enhances efflux and reduces dependence on extracellular dopamine, sodium and chloride concentrations.
Topics: Alanine; Animals; Biological Transport; Chlorides; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Proline; Rats; Sodium; Tritium | 2002 |
Three hydrates of the bisphosphonate risedronate, consisting of one molecular and two ionic structures.
Topics: Alanine; Crystallography, X-Ray; Etidronic Acid; Gadolinium; Hydrogen Bonding; Models, Molecular; Proline; Risedronic Acid | 2003 |
The effect of the polyproline II (PPII) conformation on the denatured state entropy.
Topics: Alanine; Animals; Binding Sites; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Entropy; Humans; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Mutation; Peptide Fragments; Peptides; Proline; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Son of Sevenless Proteins; src Homology Domains | 2003 |
Novel alpha-melanocyte stimulating hormone peptide analogues with high candidacidal activity.
Topics: Alanine; alpha-MSH; Amino Acid Substitution; Antifungal Agents; Candida albicans; Melanocyte-Stimulating Hormones; Peptide Fragments; Proline; Structure-Activity Relationship | 2003 |
Association of the PRO12ALA polymorphism of the PPAR-gamma2 gene with oxidized low-density lipoprotein and cardiolipin autoantibodies in nondiabetic and type 2 diabetic subjects.
Topics: Alanine; Antibodies, Anticardiolipin; Autoantibodies; Diabetes Mellitus, Type 2; Female; Genotype; Humans; Lipoproteins, LDL; Male; Middle Aged; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Reference Values; Transcription Factors | 2003 |
Structure and dynamics of the DNA-binding protein HU of B. stearothermophilus investigated by Raman and ultraviolet-resonance Raman spectroscopy.
Topics: Alanine; Arginine; Bacterial Proteins; DNA-Binding Proteins; Geobacillus stearothermophilus; Proline; Spectrum Analysis, Raman | 2003 |
Effect of the Pro12Ala polymorphism in the peroxisome proliferator-activated receptor (PPAR) gamma2 gene on the expression of PPARgamma target genes in adipose tissue of massively obese subjects.
Topics: Adipose Tissue; Adult; Alanine; Alleles; Alternative Splicing; Female; Gene Expression; Gene Frequency; Genotype; Humans; Ion Channels; Lipoprotein Lipase; Male; Membrane Transport Proteins; Middle Aged; Mitochondrial Proteins; Obesity, Morbid; Omentum; Phosphatidylinositol 3-Kinases; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Proline; Proteins; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Characteristics; Transcription Factors; Uncoupling Protein 2 | 2003 |
Chemical composition of chicken eggshell and shell membranes.
Topics: Alanine; Animals; Chickens; Egg Shell; Glycine; Hydroxyproline; Membranes; N-Acetylneuraminic Acid; Nitrogen; Proline; Uronic Acids | 2003 |
The peroxisome proliferator-activated receptor-gamma2 gene polymorphism (Pro12Ala) beneficially influences insulin resistance and its tracking from childhood to adulthood: the Bogalusa Heart Study.
Topics: Adult; Aging; Alanine; Amino Acid Substitution; Blood Glucose; Child; Genotype; Homeostasis; Humans; Insulin; Insulin Resistance; Mutation, Missense; Polymorphism, Single Nucleotide; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2003 |
Proline can be utilized as an energy substrate during flight of Aedes aegypti females.
Topics: Aedes; Alanine; Animals; Blood; Carbohydrates; Diet; Energy Metabolism; Feeding Behavior; Female; Flight, Animal; Glutamine; Hemolymph; Male; Proline; Thorax | 2003 |
Role of glutathione peroxidase 1 in breast cancer: loss of heterozygosity and allelic differences in the response to selenium.
Topics: Adenocarcinoma; Alanine; Alleles; Amino Acid Substitution; Breast Neoplasms; Codon; DNA, Neoplasm; Enzyme Induction; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Leucine; Loss of Heterozygosity; Neoplasm Proteins; Polymorphism, Genetic; Proline; Recombinant Fusion Proteins; Repetitive Sequences, Amino Acid; Selenium; Structure-Activity Relationship; Tumor Cells, Cultured | 2003 |
Inhibition of glutamine synthetase in the mouse kidney: a novel mechanism of adaptation to metabolic acidosis.
Topics: Acidosis; Actins; Alanine; Ammonia; Animals; Carbon; Female; Gluconeogenesis; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Kidney; Kidney Cortex; Kidney Tubules; Mice; Models, Biological; Nitrogen; Phosphoenolpyruvate Carboxykinase (ATP); Proline; Quaternary Ammonium Compounds; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Species Specificity; Time Factors | 2003 |
NMR and CD spectroscopy show that imino acid restriction of the unfolded state leads to efficient folding.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Circular Dichroism; Collagen Type I; Dimerization; Hydroxyproline; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Sequence Data; Peptides; Proline; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrophotometry; Temperature; Thermodynamics; Time Factors | 2003 |
Autoinhibition of Bcr-Abl through its SH3 domain.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Animals; Binding Sites; Catalytic Domain; Cell Transformation, Neoplastic; Enzyme Inhibitors; Eukaryotic Cells; Feedback, Physiological; Fusion Proteins, bcr-abl; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred BALB C; Models, Molecular; Mutation; Phosphorylation; Proline; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Tyrosine | 2003 |
Novel inhibitor for prolyl aminopeptidase from Serratia marcescens and studies on the mechanism of substrate recognition of the enzyme using the inhibitor.
Topics: Alanine; Amino Acid Sequence; Aminopeptidases; Crystallography, X-Ray; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Hydrolysis; Macromolecular Substances; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxadiazoles; Proline; Recombinant Proteins; Serratia marcescens; Substrate Specificity | 2003 |
Targeting and assembly of mitochondrial tail-anchored protein Tom5 to the TOM complex depend on a signal distinct from that of tail-anchored proteins dispersed in the membrane.
Topics: Alanine; Amino Acid Sequence; Animals; Carrier Proteins; Cell Membrane; COS Cells; DNA; Electrophoresis, Polyacrylamide Gel; Green Fluorescent Proteins; Leucine; Luminescent Proteins; Membrane Proteins; Microscopy, Fluorescence; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Precursor Protein Import Complex Proteins; Molecular Sequence Data; Phenotype; Plasmids; Proline; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Subcellular Fractions; Temperature | 2003 |
Protein-tyrosine phosphatase 1B mediates the effects of insulin on the actin cytoskeleton in immortalized fibroblasts.
Topics: Actins; Alanine; Animals; Cell Line; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Fibroblasts; Glutathione Transferase; GTP Phosphohydrolases; Insulin; Plasmids; Proline; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Rats; Recombinant Fusion Proteins; rho GTP-Binding Proteins; src Homology Domains; Time Factors | 2003 |
Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I.
Topics: Alanine; Binding Sites; Camptothecin; Catalysis; Cell Survival; DNA; DNA Topoisomerases, Type I; Drug Resistance; Enzyme Inhibitors; Humans; Ions; Kinetics; Models, Molecular; Mutation; Oligonucleotides; Plasmids; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Time Factors; Tyrosine | 2003 |
L-Serine, D- and L-proline and alanine as respiratory substrates of Helicobacter pylori: correlation between in vitro and in vivo amino acid levels.
Topics: 2,6-Dichloroindophenol; Alanine; Amino Acids; Ammonia; Gastric Juice; Helicobacter pylori; Humans; In Vitro Techniques; Oxidation-Reduction; Oxygen Consumption; Proline; Pyruvic Acid; Serine; Stereoisomerism | 2003 |
Gas-phase basicity of glycine, alanine, proline, serine, lysine, histidine and some of their peptides by the thermokinetic method.
Topics: Alanine; Amino Acids; Gases; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Peptides; Proline; Protons; Serine; Thermodynamics | 2003 |
Mutation of proline residues in the NH(2)-terminal region of the multidrug resistance protein, MRP1 (ABCC1): effects on protein expression, membrane localization, and transport function.
Topics: Alanine; Cell Membrane; HeLa Cells; Humans; Immunoblotting; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Mutation; Proline; Protein Transport | 2003 |
[Dinitrophenylene-bis-aminoacids of 2,4-dinitro-1,5-difluorbenzene, glycine, alanine, valine, proline and tyrosine].
Topics: Alanine; Amino Acids; Glycine; Proline; Tyrosine; Valine | 1954 |
The nutrition of animal tissues cultivated in vitro. IV. Amino acid requirements of chick embryonic heart fibroblasts.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Fibroblasts; Glycine; Histidine; Hydroxyproline; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
A new method for the isolation of L-alanine and L-proline from protein hydrolysates.
Topics: Alanine; Amino Acids; Proline; Protein Hydrolysates | 1957 |
Gating of shaker-type channels requires the flexibility of S6 caused by prolines.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Crystallography, X-Ray; Dose-Response Relationship, Drug; Electrophysiology; Evolution, Molecular; Glycine; Green Fluorescent Proteins; Humans; Luminescent Proteins; Microscopy, Confocal; Models, Molecular; Molecular Sequence Data; Mutation; Patch-Clamp Techniques; Potassium Channels; Proline; Protein Conformation; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Shaker Superfamily of Potassium Channels | 2003 |
Gamma irradiation of polypeptides: transformation of amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Glutamates; Glutamic Acid; Glycine; Histidine; Methionine; Peptides; Phenylalanine; Proline; Radiation Effects; Tyrosine | 1963 |
Fermentative activities of control and radiation-"killed" spores of Clostridium botulinum.
Topics: Alanine; Amino Acids; Arginine; Caseins; Clostridium botulinum; Fermentation; Glucose; Proline; Protein Hydrolysates; Radiation; Radiation Effects; Research; Spores, Bacterial | 1962 |
EFFECT OF TETRACYCLINES ON THE INTRACELLULAR AMINO ACIDS OF MOLDS.
Topics: Alanine; Amino Acids; Arginine; Fungi; Glutamic Acid; Lysine; Phenylalanine; Proline; Tetracycline; Tetracyclines; Tyrosine | 1963 |
AMINO ACID FORMATION FROM GLUCOSE IN THE ISOLATED ADRENOCORTICAL AND THYROID TISSUE OF THE RABBIT.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Alanine; Arginine; Aspartic Acid; Chromatography; Glucose; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Pharmacology; Proline; Proteins; Rabbits; Research; Thyroid Gland; Thyrotropin | 1963 |
SPECIFICITY OF PEPSIN AND ITS DEPENDENCE ON A POSSIBLE 'HYDROPHOBICBINDING SITE'.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pepsin A; Peptides; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
GAS CHROMATOGRAPHY OF AMINO ACIDS. 1. ANALYSIS OF THE MIXTURE OF METHYL-NTRIFLUOROACETYL DERIVATIVES.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography; Chromatography, Gas; Fluoroacetates; Glutamates; Glycine; Hydroxyproline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1963 |
AMINO-ACID CONFIGURATION OF MYCOBACILLIN.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Antifungal Agents; Aspartic Acid; Chemistry Techniques, Analytical; Glutamates; Leucine; Mycobacillin; Proline; Research; Serine; Tyrosine | 1963 |
[ON THE RADIATION-PROTECTIVE EFFECT OF ALANINE AND PROLINE ON HEREDITARY STRUCTURES OF MAMMALIAN BONE MARROW CELLS].
Topics: Alanine; Animals; Bone Marrow; Bone Marrow Cells; Cell Nucleus; Chromosome Aberrations; Chromosome Disorders; Mice; Proline; Radiation-Protective Agents; Research | 1963 |
INSULIN AND INCORPORATION OF AMINO ACIDS INTO PROTEIN OF MUSCLE. 1. ACCUMULATION AND INCORPORATION STUDIES WITH THE PERFUSED RAT HEART.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Azides; Carbon Isotopes; Cyanides; Glutamates; Glycine; Insulin; Lysine; Muscles; Myocardium; Perfusion; Pharmacology; Phenylalanine; Proline; Proteins; Rats; Research; Tyrosine; Valine | 1963 |
THE INHIBITION OF CEREBRAL DIGLYCINASE BY ALPHA-AMINO-, ALPHA-KETO- AND ALPHA-HYDROXY ACIDS.
Topics: Alanine; Aminobutyrates; Animals; Arginine; Aspartic Acid; Brain; Cobalt; Enzyme Inhibitors; Histidine; Hydroxy Acids; Keto Acids; Leucine; Methionine; Mice; Peptide Hydrolases; Peptides; Pharmacology; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Valine | 1963 |
OXIDATION OF L-AMINO ACIDS AND INCORPORATION INTO PROTEIN IN HOMOGENATES OF BRAIN AT TWO STAGES OF DEVELOPMENT.
Topics: Alanine; Amino Acids; Arginine; Autoradiography; Brain; Carbon Isotopes; Chromatography; Glycine; Histidine; Isoleucine; Keto Acids; Leucine; Lysine; Mice; Nerve Tissue Proteins; Phenylalanine; Proline; Proteins; Pyruvates; Research; Serine; Threonine; Valine | 1963 |
[ON THE QUANTITATIVE DETERMINATION OF AMINO ACIDS USING HIGH VOLTAGE ELECTROPHORESIS].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Blood Protein Electrophoresis; Glutamates; Histidine; Leucine; Lysine; Methionine; Ornithine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
BIOCHEMISTRY OF LUNGS IN RELATION TO SILICOSIS. II. THE EFFECT OF QUARTZ DUST ON THE PROTEIN AMINO ACIDS OF GUINEA PIG LUNG TISSUE.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Collagen; Cystine; Dust; Glutamates; Glycine; Guinea Pigs; Histidine; Hydroxyproline; Isoleucine; Leucine; Lung; Lysine; Methionine; Phenylalanine; Proline; Quartz; Research; Serine; Silicon Dioxide; Silicosis; Threonine; Toxicology; Tyrosine; Valine | 1964 |
NITROGEN BALANCES FOR YOUNG ADULT MALES FED TWO SOURCES OF NONESSENTIAL NITROGEN AT TWO LEVELS OF TOTAL NITROGEN INTAKE.
Topics: Alanine; Ammonium Compounds; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Male; Nitrogen; Nitrogen Fixation; Proline; Proteins; Quaternary Ammonium Compounds; Serine | 1964 |
EFFECT OF SPORULATION MEDIUM ON HEAT RESISTANCE, CHEMICAL COMPOSITION, AND GERMINATION OF BACILLUS MEGATERIUM SPORES.
Topics: Alanine; Bacillus megaterium; Bacteriological Techniques; Biochemical Phenomena; Biochemistry; Culture Media; Glucose; Glutamates; Glutamic Acid; Hot Temperature; Leucine; Nitrates; Phosphates; Picolinic Acids; Potassium; Proline; Research; Spores; Spores, Bacterial | 1964 |
THE ROLE OF DISPENSABLE AMINO ACIDS IN THE NUTRITION OF THE RAT.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bicarbonates; Caseins; Cystine; Dietary Proteins; Glutamates; Glycine; Growth; Histidine; Isoleucine; Lysine; Methionine; Phenylalanine; Proline; Proteins; Rats; Research; Serine; Tyrosine | 1964 |
DYNAMIC PHENOMENA IN MICROSPHERES FROM THERMAL PROTEINOID.
Topics: Alanine; Arginine; Aspartic Acid; Colloids; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Microspheres; Peptides; Phenylalanine; Photomicrography; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
[SEPARATION OF AMINO ACIDS BY CHROMATOGRAPHY ON THIN LAYERS OF DIETHYLAMINOETHYL CELLULOSE].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
THE INHIBITION OF MITOCHONDRIAL ADENOSINE TRIPHOSPHATASE. 2. THE EFFECTS OF AMINO ACIDS AND SUGARS.
Topics: Adenosine Triphosphatases; Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Enzyme Inhibitors; Fructose; Glutamates; Glycine; Histidine; Hydroxyproline; Isoleucine; Lactose; Liver; Lysine; Methionine; Mitochondria; Oligosaccharides; Pharmacology; Proline; Rats; Research; Serine; Threonine; Valine | 1964 |
PLASMA AMINO ACID PATTERNS IN ALCOHOLISM: THE EFFECTS OF ETHANOL LOADING.
Topics: Alanine; Alcoholism; Amino Acids; Autoanalysis; Biomedical Research; Blood; Ethanol; Genetics, Medical; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Methionine; NAD; NADP; Proline; Proteins; Serine; Toxicology; Valine | 1964 |
AN ANALYSIS OF THE OPTICAL ROTATORY DISPERSION OF POLYPEPTIDES AND PROTEINS.
Topics: Alanine; Animals; Cattle; Chemical Phenomena; Chemistry; Fibrinogen; Globulins; Glutamates; Lysine; Muscle Proteins; Optical Rotatory Dispersion; Peptides; Proline; Proteins; Research; Ribonucleases; Serine; Serum Albumin; Serum Albumin, Bovine | 1964 |
INFLUENCE OF BETA-AMINOPROPIONITRILE ON DISSECTING ANEURYSM AND ON PLASMA AMINO ACIDS IN THE TURKEY.
Topics: Alanine; Amino Acids; Aminopropionitrile; Ammonia; Aneurysm; Animals; Aortic Dissection; Arginine; Autoanalysis; Blood; Chromatography; Collagen; Cyanides; Diet; Histidine; Isoleucine; Leucine; Lysine; Pharmacology; Poultry; Proline; Proteins; Research; Turkey; Valine | 1964 |
STUDIES ON THE HYDROLYTIC ACTION OF PRONASE ON DERIVATIZED AND NON-DERIVATIZED PROTEINS.
Topics: Alanine; Arginine; Asparagine; Cystine; Dinitrophenols; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptide Hydrolases; Phenylalanine; Proline; Pronase; Proteins; Research; Ribonucleases; Streptomyces; Threonine; Tyrosine; Valine | 1964 |
AMINO ACID COMPOSITION OF BULK PROTEIN OF EUGLENA GROWN IN WASTE WATER.
Topics: Alanine; Amino Acids; Animals; Euglena; Histidine; Methionine; Proline; Proteins; Research; Sewage; Threonine; Tryptophan; Valine; Wastewater | 1964 |
[FREE PLASMA AMINO ACIDS IN LIVER CIRRHOSIS AND HEPATITIS].
Topics: Alanine; Amino Acids; Blood; Chromatography; Glutamine; Glycine; Hepatitis; Humans; Ion Exchange Resins; Liver Cirrhosis; Methionine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine | 1964 |
INACTIVATION OF SOLUBLE RIBONUCLEIC ACID BY ELECTRON IRRADIATION.
Topics: Alanine; Amino Acids; Carbon Isotopes; Electrons; Isoleucine; Leucine; Liver; Methionine; Proline; Radiation Effects; Rats; Research; RNA; Saccharomyces; Tritium; Valine | 1964 |
MYOGLOBIN FREE-RADICALS.
Topics: Alanine; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Glycine; Histidine; Hydrogen Peroxide; Leucine; Myoglobin; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
PHYSIOLOGY OF THE SPORULATION PROCESS IN CLOSTRIDIUM BOTULINUM. I. CORRELATION OF MORPHOLOGICAL CHANGES WITH CATABOLIC ACTIVITIES, SYNTHESIS OF DIPICOLINIC ACID, AND DEVELOPMENT OF HEAT RESISTANCE.
Topics: Acetates; Alanine; Caseins; Clostridium botulinum; Fatty Acids; Fermentation; Hot Temperature; Hydrogen-Ion Concentration; Metabolism; Pharmacology; Picolinic Acids; Proline; Propionates; Protein Hydrolysates; Pyridines; Research; Spores; Spores, Bacterial; Thiamine | 1964 |
PHYSIOLOGY OF THE SPORULATION PROCESS IN CLOSTRIDIUM BOTULINUM. II. MATURATION OF FORESPORES.
Topics: Acetates; Alanine; Amino Acids; Arginine; Carbon Dioxide; Carbon Isotopes; Citrulline; Clostridium botulinum; DNA; DNA, Bacterial; Fatty Acids; Fermentation; Hot Temperature; Isoleucine; Metabolism; Ornithine; Phosphorus Isotopes; Picolinic Acids; Proline; Research; RNA; RNA, Bacterial; Spores; Spores, Bacterial | 1964 |
SOME PROPERTIES OF METHANOBACTERIUM OMELIANSKII FERREDOXIN.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacteria; Chemistry Techniques, Analytical; Cystine; Ferredoxins; Glutamates; Glycine; Iron; Lysine; Methanobacterium; Proline; Serine; Spectrophotometry; Sulfides; Threonine; Tyrosine; Valine | 1964 |
GEL FILTRATION PROPERTIES OF CCD-PREPARED E. COLI B SRNA.
Topics: Alanine; Chromatography; Chromatography, Gel; Countercurrent Distribution; Escherichia coli; Leucine; Proline; Research; RNA; RNA, Bacterial | 1964 |
AMINO ACIDS AS PROTECTIVE COMPOUNDS IN ULTRAVIOLET-IRRADIATED HANSENULA WINGEI.
Topics: Alanine; Amino Acids; Arginine; Cysteine; Cystine; Ethionine; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Pichia; Proline; Radiation-Protective Agents; Research; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays; Valine; Yeasts | 1964 |
OXIDATION OF L-PROLINE AND L-3,4-DEHYDROPROLINE BY D-AMINO ACID OXIDASE.
Topics: Alanine; Amino Acid Oxidoreductases; Amino Acids; Benzoates; Catalysis; D-Amino-Acid Oxidase; Oxidation-Reduction; Proline; Research | 1964 |
INHIBITION OF ADP-INDUCED PLATELET AGGREGATION BY SUBSTITUTED AMINO-ACIDS.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Alanine; Alkylation; Amino Acids; Aminocaproates; Aminocaproic Acid; Arginine; Blood Platelets; Butyrates; Glutamine; Glycine; Guanidines; Leucine; Pharmacology; Phenylalanine; Platelet Aggregation; Proline; Research; Thrombosis; Tyrosine | 1964 |
[APPLICATION OF THIN-LAYER CHROMATOGRAPHY TO SEQUENCE ANALYSIS OF PEPTIDES. 3. NONDESTRUCTIVE DETECTION OF AMINO ACIDS ON THE THIN-LAYER CHROMATOGRAM].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chromatography; Chromatography, Thin Layer; Histidine; Peptides; Proline; Research; Sequence Analysis; Serine; Tyrosine; Valine | 1964 |
RAT LIVER ENZYME DOES NOT ACTIVATE ACETYLAMINO ACIDS.
Topics: Acetates; Adenosine Triphosphate; Alanine; Amino Acids; Arginine; Diphosphates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Liver; Lysine; Methionine; Phenylalanine; Proline; Rats; Research; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
RESOLUTION OF AMINO ACIDS BY GAS CHROMATOGRAPHY.
Topics: Alanine; Alcohols; Amino Acids; Chromatography; Chromatography, Gas; Glutamates; Leucine; Phenylalanine; Proline; Research; Valine | 1965 |
EFFECTS OF IMBALANCES OR ANTAGONISMS AMONG NONESSENTIAL AMINO ACIDS ON GROWTH AND NITROGEN UTILIZATION BY RATS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Dietary Proteins; Glutamates; Glycine; Growth; Hydroxyproline; Metabolism; Methionine; Nitrogen; Pharmacology; Proline; Rats; Research | 1965 |
EFFECT OF AMINO ACIDS ON GROWTH OF SPHAEROTILUS DISCOPHORUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Bacteriological Techniques; Caseins; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Proline; Research; Serine; Sphaerotilus; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
HIGH SENSITIVITY OPTICAL RESOLUTION OF D,L AMINO ACIDS BY GAS CHROMATOGRAPHY.
Topics: Alanine; Amino Acids; Chromatography; Chromatography, Gas; Leucine; Methionine; Phenylalanine; Proline; Research; Tyrothricin; Valine | 1965 |
DECREASE IN APPETITE AND BIOCHEMICAL CHANGES IN AMINO ACID IMBALANCE IN THE RAT.
Topics: Alanine; Amino Acids; Appetite; Biochemical Phenomena; Biochemistry; Diet; Dietary Proteins; Glutamates; Glutens; Isoleucine; Kwashiorkor; Leucine; Liver; Lysine; Muscles; Proline; Rats; Research; Serine; Threonine; Valine | 1965 |
BITTER PEPTIDE ISOLATED FROM MILK CULTURES OF STREPTOCOCCUS CREMORIS.
Topics: Alanine; Amino Acids; Arginine; Butanones; Carboxypeptidases; Chemical Phenomena; Chemistry; Chemistry Techniques, Analytical; Chromatography; Culture Media; Electrophoresis; Glutamates; Glycine; Histidine; Indicators and Reagents; Isoleucine; Leucine; Lysine; Metabolism; Methionine; Milk; Peptide Hydrolases; Peptides; Phenylalanine; Proline; Research; Streptococcus; Threonine; Tyrosine; Valine | 1965 |
RECENT DEVELOPMENTS IN THE UNDERSTANDING OF AMINO-ACID AND PROTEIN METABOLISM BY SCHISTOSOMA MANSONI IN VITRO.
Topics: Alanine; Amino Acids; Animals; Arginase; Arginine; Aspartic Acid; Carbon Isotopes; Glucose; Hemoglobins; Histidine; In Vitro Techniques; Ornithine; Peptides; Proline; Proteins; Radiometry; Research; Schistosoma; Schistosoma mansoni; Tryptophan; Urea | 1965 |
Conditions affecting Bacillus megaterium spore germination in glucose or various nitrogenous compounds.
Topics: Alanine; Bacillus; Bacillus megaterium; Culture Media; Glucose; Leucine; Nitrogen; Nitrogen Compounds; Proline; Spores, Bacterial; Valine | 1962 |
Nitrogenous compounds in germination and postgerminative development of Bacillus megaterium spores.
Topics: Alanine; Arginine; Asparagine; Bacillus; Bacillus megaterium; Culture Media; Cysteine; Hot Temperature; Leucine; Nitrates; Nitrogen; Proline; Spores, Bacterial; Valine | 1962 |
Effect of proline to alanine mutation on the thermal stability of the all-beta-sheet protein tendamistat.
Topics: Alanine; Enzyme Inhibitors; Models, Molecular; Mutation; Peptides; Proline; Protein Denaturation; Protein Structure, Secondary; Protein Structure, Tertiary; Spectroscopy, Fourier Transform Infrared; Temperature | 2003 |
Prospective study of the association between the proline to alanine codon 12 polymorphism in the PPARgamma gene and type 2 diabetes.
Topics: Alanine; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Heterozygote; Homozygote; Humans; Incidence; Middle Aged; Polymorphism, Genetic; Proline; Prospective Studies; Receptors, Cytoplasmic and Nuclear; Risk Factors; Transcription Factors | 2003 |
A pilot study to investigate effects of inulin on Caco-2 cells through in vitro metabolic fingerprinting.
Topics: Alanine; Analysis of Variance; Caco-2 Cells; Colon; Fermentation; Glucose; Glutamic Acid; Humans; Inulin; Ketoglutaric Acids; Lactic Acid; Magnetic Resonance Spectroscopy; Niacin; Niacinamide; Proline; Succinic Acid | 2003 |
An isolated class II aminoacyl-tRNA synthetase insertion domain is functional in amino acid editing.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Amino Acyl-tRNA Synthetases; Bacterial Proteins; Base Sequence; Binding Sites; Circular Dichroism; Escherichia coli; Gene Deletion; Haemophilus influenzae; Hydrolysis; Models, Molecular; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Plasmids; Proline; Protein Structure, Tertiary; RNA; RNA, Transfer; RNA, Transfer, Amino Acyl; Sequence Homology, Amino Acid; Time Factors | 2003 |
The Pro12Ala polymorphism of PPARgamma2 gene and susceptibility to type 2 diabetes mellitus in a Polish population.
Topics: Age of Onset; Alanine; Amino Acid Substitution; Body Mass Index; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Genotype; Glycated Hemoglobin; Humans; Middle Aged; Poland; Polymorphism, Restriction Fragment Length; Proline; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Reference Values; Transcription Factors; White People | 2003 |
The association of Pro12Ala polymorphism in PPARgamma2 with lower carotid artery IMT in Japanese.
Topics: Adult; Aged; Alanine; Arteriosclerosis; Base Sequence; Body Mass Index; Carotid Arteries; Diabetes Mellitus, Type 2; DNA; DNA Primers; Humans; Japan; Middle Aged; Polymorphism, Single Nucleotide; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tunica Intima; Tunica Media | 2003 |
Modulating calcitonin fibrillogenesis: an antiparallel alpha-helical dimer inhibits fibrillation of salmon calcitonin.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Arginine; Calcitonin; Chromatography, Gel; Circular Dichroism; Dimerization; Dose-Response Relationship, Drug; Guanidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Leucine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Peptides; Proline; Protein Folding; Protein Structure, Secondary; Salmon; Sequence Homology, Amino Acid | 2004 |
Stabilization of a chitinase from Serratia marcescens by Gly-->Ala and Xxx-->Pro mutations.
Topics: Alanine; Amino Acid Substitution; Chitinases; Circular Dichroism; Enzyme Stability; Glycine; Kinetics; Models, Molecular; Proline; Protein Denaturation; Protein Structure, Secondary; Serratia marcescens; Thermolysin | 2003 |
The structure of tri-proline in water probed by polarized Raman, Fourier transform infrared, vibrational circular dichroism, and electric ultraviolet circular dichroism spectroscopy.
Topics: Alanine; Circular Dichroism; Hot Temperature; Oligopeptides; Proline; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 2003 |
Does peroxisome proliferator-activated receptor gamma genotype (Pro12ala) modify the association of physical activity and dietary fat with fasting insulin level?
Topics: Adult; Aged; Alanine; Alleles; Body Mass Index; Cohort Studies; Diet Records; Dietary Fats; Energy Metabolism; Exercise; Fasting; Fatty Acids; Fatty Acids, Unsaturated; Female; Genotype; Heart Rate; Humans; Insulin; Male; Middle Aged; Polymorphism, Genetic; Proline; Prospective Studies; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Surveys and Questionnaires; Transcription Factors | 2004 |
A novel missense mutation of the MEN1 gene in a multiple endocrine neoplasia type 1 patient associated with carcinoid syndrome.
Topics: Alanine; Carcinoid Tumor; DNA Mutational Analysis; Duodenal Neoplasms; Female; Fluorescence; Humans; Hyperparathyroidism; Immunohistochemistry; Liver Neoplasms; Loss of Heterozygosity; Microsatellite Repeats; Middle Aged; Multiple Endocrine Neoplasia Type 1; Mutation, Missense; Pancreatic Neoplasms; Parathyroid Glands; Proline | 2003 |
Roles of the proline-rich domain in SLP-76 subcellular localization and T cell function.
Topics: Adaptor Proteins, Signal Transducing; Alanine; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Arginine; Blotting, Western; Calcium; Cell Line; Cell Lineage; Flow Cytometry; Gene Deletion; Genes, Dominant; Hematopoietic Stem Cells; Humans; Jurkat Cells; Lectins, C-Type; Luciferases; Lymphocyte Activation; Lysine; Membrane Microdomains; Models, Biological; Mutation; Phosphoproteins; Plasmids; Precipitin Tests; Proline; Protein Structure, Tertiary; Signal Transduction; src Homology Domains; Subcellular Fractions; T-Lymphocytes; Time Factors; Transfection | 2004 |
Identification of proline residues in the core cytoplasmic and transmembrane regions of multidrug resistance protein 1 (MRP1/ABCC1) important for transport function, substrate specificity, and nucleotide interactions.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Anions; Biological Transport; Blotting, Northern; Cell Line; Cell Membrane; Cytoplasm; Dose-Response Relationship, Drug; Genetic Vectors; Humans; Kidney; Kinetics; Methotrexate; Microscopy, Confocal; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Mutation; Nucleotides; Proline; Protein Binding; Protein Transport; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Substrate Specificity; Transfection; Vanadates | 2004 |
Investigating the importance of the flexible hinge in caerin 1.1: solution structures and activity of two synthetically modified caerin peptides.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amphibian Proteins; Animals; Antimicrobial Cationic Peptides; Anura; Bacteria; Glycine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Microbial Sensitivity Tests; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Proline; Protein Conformation; Protein Structure, Secondary; Solutions; Structure-Activity Relationship; Thermodynamics | 2004 |
Influence of the polymorphisms Tpr64Arg in the beta 3-adrenergic receptor gene and Pro12Ala in the PPAR gamma 2 gene on metabolic syndrome-related phenotypes in an indigenous population of the Brazilian Amazon.
Topics: Alanine; Arginine; Brazil; Female; Humans; Male; Metabolic Syndrome; Obesity; Phenotype; Polymorphism, Single Nucleotide; Proline; Racial Groups; Receptors, Adrenergic, beta-3; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tryptophan | 2004 |
Trypsin disrupts the trafficking of the human dopamine transporter by alpha-synuclein and its A30P mutant.
Topics: Alanine; alpha-Synuclein; Amino Acid Substitution; Animals; Biotinylation; Cell Death; Cell Line; Cell Line, Tumor; Cells, Cultured; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Proline; Protein Transport; Rats; Synucleins; Transfection; Trypsin | 2004 |
Enzymatic mechanism of low-activity mouse alcohol dehydrogenase 2.
Topics: Alanine; Alcohol Dehydrogenase; Amino Acid Substitution; Animals; Benzyl Alcohol; Catalysis; Deuterium Exchange Measurement; Enzyme Activation; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Mice; Mutagenesis, Site-Directed; Proline; Recombinant Proteins; Substrate Specificity | 2004 |
Effects of the hydroxyl radical and hydrogen peroxide on tooth bleaching.
Topics: Alanine; Dentin; Durapatite; Electron Spin Resonance Spectroscopy; Glycine; Humans; Hydrogen Peroxide; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Oxidants; Proline; Tooth Bleaching; Tooth Discoloration; X-Ray Diffraction | 2004 |
The disassembly and reassembly of mutants of Escherichia coli heat-labile enterotoxin: replacement of proline 93 does not abolish the reassembly-competent and reassembly-incompetent states.
Topics: Alanine; Amino Acid Substitution; Bacterial Toxins; Enterotoxins; Escherichia coli Proteins; Glycine; Hydrogen-Ion Concentration; Kinetics; Ligands; Mutagenesis, Site-Directed; Proline; Protein Binding; Protein Conformation; Protein Denaturation; Protein Processing, Post-Translational; Protein Renaturation; Protein Subunits; Recombinant Proteins; Vibrio | 2004 |
Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands.
Topics: Alanine; Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cycloserine; Databases as Topic; Escherichia coli; Excitatory Amino Acid Antagonists; Glycine; Humans; Hydrogen Bonding; Indoles; Kynurenic Acid; Ligands; Mice; Models, Chemical; Models, Molecular; Molecular Sequence Data; Potassium Channels; Proline; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sequence Homology, Amino Acid; Serine; Threonine; Tryptophan; Water | 2004 |
Spinal phenotype of cerebrotendinous xanthomatosis--a pitfall in the diagnosis of multiple sclerosis.
Topics: Age of Onset; Alanine; Bile Acids and Salts; Cholestanetriol 26-Monooxygenase; Cholestanol; Cholesterol; Diagnosis, Differential; Diagnostic Errors; Diarrhea; DNA Mutational Analysis; Family Health; Female; Heterozygote; Humans; Magnetic Resonance Imaging; Middle Aged; Muscular Atrophy, Spinal; Mutation; Phenotype; Proline; Steroid Hydroxylases; Xanthomatosis, Cerebrotendinous | 2004 |
Identification and characterization of a nitrate transporter gene in Neurospora crassa.
Topics: Alanine; Amino Acid Sequence; Anion Transport Proteins; Cesium; Chlorates; DNA-Binding Proteins; Fungal Proteins; Gene Expression Regulation, Fungal; Glutamine; Half-Life; Hypoxanthine; Molecular Sequence Data; Mutation; Neurospora crassa; Nitrate Transporters; Polymorphism, Restriction Fragment Length; Proline; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Trans-Activators; Transcription Factors | 2004 |
Effects of Parkinson's disease-linked mutations on the structure of lipid-associated alpha-synuclein.
Topics: Alanine; alpha-Synuclein; Humans; Lipid Metabolism; Liposomes; Micelles; Mutation, Missense; Nerve Tissue Proteins; Nuclear Magnetic Resonance, Biomolecular; Parkinson Disease; Phosphatidic Acids; Phosphatidylcholines; Proline; Protein Binding; Protein Structure, Secondary; Recombinant Proteins; Synucleins; Threonine | 2004 |
Role of the conserved arginine pair in proton and electron transfer in cytochrome C oxidase.
Topics: Alanine; Arginine; Catalysis; Conserved Sequence; Electron Spin Resonance Spectroscopy; Electron Transport; Electron Transport Complex IV; Enzyme Activation; Glutamine; Heme; Kinetics; Lysine; Magnesium; Mutagenesis, Site-Directed; Photolysis; Proline; Proton Pumps; Rhodobacter sphaeroides; Spectrophotometry, Ultraviolet | 2004 |
Short sequences of non-proline residues can adopt the polyproline II helical conformation.
Topics: Alanine; Amino Acid Sequence; Asparagine; Circular Dichroism; Glutamine; Oligopeptides; Peptides; Proline; Protein Conformation; Protein Structure, Secondary; Spectrophotometry; Valine | 2004 |
Hepatitis C virus glycoprotein E2 contains a membrane-proximal heptad repeat sequence that is essential for E1E2 glycoprotein heterodimerization and viral entry.
Topics: Alanine; Amino Acid Sequence; Animals; Blotting, Western; Cell Line; COS Cells; Dimerization; Genetic Vectors; Glycoproteins; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Precipitin Tests; Proline; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Serine; Transfection; Viral Envelope Proteins | 2004 |
NMR structure of the alpha-hemoglobin stabilizing protein: insights into conformational heterogeneity and binding.
Topics: Alanine; Binding Sites; Blood Proteins; Cloning, Molecular; Dimerization; DNA; DNA, Complementary; Gene Library; Humans; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Chaperones; Mutation; Plasmids; Point Mutation; Proline; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Secondary; Protein Structure, Tertiary; Tyrosine | 2004 |
Hb Cardarelli [beta86(F2)Ala-->Pro]: a new unstable and hyperaffine variant in association with beta(+)-thalassemia.
Topics: Adult; Aged; Alanine; Amino Acid Substitution; beta-Thalassemia; Child; Child, Preschool; Codon; DNA Mutational Analysis; Family; Globins; Hemoglobins, Abnormal; Humans; Italy; Male; Middle Aged; Oxygen; Pedigree; Polycythemia; Proline; Substrate Specificity | 2004 |
Lack of major involvement of human uroplakin genes in vesicoureteral reflux: implications for disease heterogeneity.
Topics: Alanine; Amino Acid Substitution; Animals; Base Sequence; Case-Control Studies; Chromosome Mapping; Cytosine; Embryo, Mammalian; Exons; Gene Expression; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Introns; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation, Missense; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Proline; Thymine; Uroplakin Ia; Uroplakin Ib; Uroplakin II; Uroplakin III; Urothelium; Vesico-Ureteral Reflux | 2004 |
The critical features and the mechanism of inhibition of a kinase interaction motif-based peptide inhibitor of JNK.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Motifs; Animals; beta-Galactosidase; Binding, Competitive; COS Cells; Databases as Topic; Dose-Response Relationship, Drug; Enzyme Inhibitors; JNK Mitogen-Activated Protein Kinases; Kinetics; Leucine; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Peptides; Plasmids; Proline; Protein Binding; Protein Structure, Tertiary; Temperature; Threonine; Transfection; Two-Hybrid System Techniques | 2004 |
[Association of Pro12Ala mutation in peroxisome proliferator-activated receptor gamma 2 with obesity and diabetes in Chinese population].
Topics: Adult; Alanine; Diabetes Mellitus; Female; Gene Frequency; Humans; Male; Mutation; Obesity; Polymorphism, Restriction Fragment Length; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2004 |
Increased risk of bladder cancer associated with a glutathione peroxidase 1 codon 198 variant.
Topics: Aged; Alanine; Asian People; Carcinoma, Transitional Cell; Female; Genetic Predisposition to Disease; Genotype; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Leucine; Logistic Models; Male; Middle Aged; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Genetic; Proline; Superoxide Dismutase; Urinary Bladder Neoplasms; Valine | 2004 |
A functional aquaporin co-localizes with the vacuolar proton pyrophosphatase to acidocalcisomes and the contractile vacuole complex of Trypanosoma cruzi.
Topics: Alanine; Amino Acid Sequence; Animals; Aquaporins; Asparagine; Blotting, Northern; Blotting, Southern; Blotting, Western; Cloning, Molecular; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glycerol; Green Fluorescent Proteins; Immunoblotting; Immunohistochemistry; Luminescent Proteins; Microscopy, Electron; Microscopy, Fluorescence; Molecular Sequence Data; Oocytes; Osmosis; Peptides; Phylogeny; Plasmids; Proline; Protein Structure, Tertiary; Protons; Pyrophosphatases; Saccharomyces cerevisiae; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Time Factors; Transfection; Trypanosoma cruzi; Vacuoles; Xenopus laevis | 2004 |
Synthesis of 3 10-helix-inducing constrained analogues of L-proline.
Topics: Alanine; Carboxylic Acids; Circular Dichroism; Crystallography, X-Ray; Models, Molecular; Oligopeptides; Proline; Protein Conformation; Stereoisomerism | 2004 |
Contribution of the alanine-rich region of Streptococcus mutans P1 to antigenicity, surface expression, and interaction with the proline-rich repeat domain.
Topics: Alanine; Antibodies, Bacterial; Antibodies, Monoclonal; Bacterial Proteins; Cell Membrane; Escherichia coli; Humans; Membrane Glycoproteins; Proline; Repetitive Sequences, Nucleic Acid; Sequence Deletion; Streptococcus mutans | 2004 |
A common antitussive drug, clobutinol, precipitates the long QT syndrome 2.
Topics: Alanine; Amino Alcohols; Animals; Antitussive Agents; Arrhythmias, Cardiac; Cation Transport Proteins; Chlorocebus aethiops; COS Cells; Electrophysiology; Ether-A-Go-Go Potassium Channels; Humans; Long QT Syndrome; Male; Mutation; Pedigree; Potassium Channels, Voltage-Gated; Proline; Threonine; Valine | 2004 |
Alanine-scanning mutagenesis in the signature disulfide loop of the glycine receptor alpha 1 subunit: critical residues for activation and modulation.
Topics: Alanine; Allosteric Regulation; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Cell Line; Conserved Sequence; Cysteine; Disulfides; Humans; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Proline; Protein Structure, Tertiary; Protein Subunits; Receptors, Glycine; Tryptophan | 2004 |
The effect of sugar, amino acid, metal ion, and NaCl on model Maillard reaction under pH control.
Topics: Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Biochemistry; Carbohydrates; Colorimetry; Copper; Cysteine; Fructose; Glucose; Glutamic Acid; Glycine max; Hot Temperature; Hydrogen-Ion Concentration; Ions; Iron; Isoleucine; Leucine; Lysine; Maltose; Metals; Models, Chemical; Phenylalanine; Proline; Serine; Sodium Chloride; Temperature; Time Factors; Valine; Xylose | 2004 |
High incidence of type 2 diabetes in peroxisome proliferator-activated receptor gamma2 Pro12Ala carriers exposed to a high chronic intake of trans fatty acids and saturated fatty acids.
Topics: Adult; Alanine; Amino Acid Substitution; Diabetes Mellitus, Type 2; Dietary Fats; Energy Intake; Female; Genetic Carrier Screening; Humans; Male; Middle Aged; Pilot Projects; Point Mutation; Polymorphism, Single Nucleotide; PPAR gamma; Proline; Risk Factors; Trans Fatty Acids; Uruguay | 2004 |
Metabolic properties of Eubacterium pyruvativorans, a ruminal 'hyper-ammonia-producing' anaerobe with metabolic properties analogous to those of Clostridium kluyveri.
Topics: Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; Caseins; Clostridium; Crotonates; Energy Metabolism; Eubacterium; Fatty Acids, Volatile; Fermentation; Glycine; Lactic Acid; Leucine; Peptides; Proline; Pyruvic Acid; Rumen; Serine; Threonine | 2004 |
Expression of a nonpolymerizable actin mutant in Sf9 cells.
Topics: Actins; Alanine; Animals; Baculoviridae; Ca(2+) Mg(2+)-ATPase; Cell Line; Cross-Linking Reagents; Drosophila Proteins; Enzyme Activation; Genetic Vectors; Humans; Mutagenesis, Site-Directed; Myosin Subfragments; Point Mutation; Polymers; Proline; Protein Binding; Protein Isoforms; Spodoptera | 2004 |
Association of male infertility with Pro185Ala polymorphism in the aryl hydrocarbon receptor repressor gene: implication for the susceptibility to dioxins.
Topics: Adult; Alanine; Alleles; Basic Helix-Loop-Helix Transcription Factors; Case-Control Studies; Dioxins; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Infertility, Male; Male; Middle Aged; Oligospermia; Polymorphism, Genetic; Proline; Receptors, Aryl Hydrocarbon; Repressor Proteins; Trinucleotide Repeats | 2004 |
Many amino acid substitutions in a hypoxia-inducible transcription factor (HIF)-1alpha-like peptide cause only minor changes in its hydroxylation by the HIF prolyl 4-hydroxylases: substitution of 3,4-dehydroproline or azetidine-2-carboxylic acid for the p
Topics: Alanine; Amino Acid Motifs; Animals; Azetidinecarboxylic Acid; Baculoviridae; Cell Line; Chromatography, Liquid; Culture Media, Serum-Free; Glutamic Acid; Humans; Hydroxylation; Hypoxia-Inducible Factor 1, alpha Subunit; Insecta; Ketoglutaric Acids; Kinetics; Leucine; Mass Spectrometry; Methionine; Models, Chemical; Peptides; Procollagen-Proline Dioxygenase; Proline; Protein Structure, Tertiary; Substrate Specificity; Time Factors; Transcription Factors | 2004 |
Cardiovascular risk in type 2 diabetes is associated with variation at the PPARG locus: a Go-DARTS study.
Topics: Age Factors; Alanine; Alleles; Amino Acid Substitution; Cardiovascular Diseases; Cohort Studies; Cytosine; Diabetes Mellitus, Type 2; Female; Genetic Testing; Genetic Variation; Humans; Male; Middle Aged; Myocardial Infarction; Polymorphism, Genetic; PPAR gamma; Proline; Risk Factors; Sex Factors; Smoking; Thymine | 2004 |
[Is obesity associated with a polymorphism Pro12Ala and Pro115Gln in PPARgamma gene?].
Topics: Alanine; Case-Control Studies; Female; Glutamine; Heterozygote; Homozygote; Humans; Male; Obesity; Poland; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; PPAR gamma; Proline; Sex Factors | 2004 |
Gender dependent association of thrombospondin-4 A387P polymorphism with myocardial infarction.
Topics: Alanine; Amino Acid Substitution; Case-Control Studies; Female; Humans; Male; Middle Aged; Myocardial Infarction; Polymorphism, Genetic; Proline; Sex Factors; Thrombospondins | 2004 |
Lattice corneal dystrophy associated with the Ala546Asp and Pro551Gln missense changes in the TGFBI gene.
Topics: Adult; Alanine; Amyloid; Amyloidosis; Aspartic Acid; Cornea; Corneal Dystrophies, Hereditary; DNA Mutational Analysis; Exons; Extracellular Matrix Proteins; Female; Glutamine; Haplotypes; Humans; Mutation, Missense; Pedigree; Proline; Transforming Growth Factor beta | 2004 |
PPAR-gamma2 Pro12Ala variant is associated with greater insulin sensitivity in childhood obesity.
Topics: Adolescent; Alanine; Child; Exons; Female; Genetic Variation; Genotype; Humans; Insulin; Insulin Resistance; Italy; Linear Models; Male; Mutation, Missense; Obesity; Phenotype; Polymorphism, Genetic; PPAR gamma; Proline; Risk Factors | 2005 |
Induced fit of an epitope peptide to a monoclonal antibody probed with a novel parallel surface plasmon resonance assay.
Topics: Alanine; Animals; Antibodies, Monoclonal; Biosensing Techniques; Biotinylation; Epitope Mapping; Epitopes; Glycine; Hybridomas; Kinetics; Ligands; Mice; Models, Chemical; Models, Molecular; Mutation; Peptides; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Surface Plasmon Resonance; Time Factors | 2005 |
The PPAR{gamma} Pro12Ala polymorphism and risk for incident sporadic colorectal adenomas.
Topics: Adenoma; Adult; Aged; Alanine; Colorectal Neoplasms; Female; Heterozygote; Humans; Male; Middle Aged; Multivariate Analysis; Polymorphism, Genetic; PPAR gamma; Proline; Risk Factors | 2005 |
The frequency of alleles of the Pro12Ala polymorphism in PPARgamma2 is different between healthy controls and patients with type 2 diabetes.
Topics: Adult; Aged; Alanine; Alleles; Case-Control Studies; Czech Republic; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Lipids; Male; Middle Aged; Polymorphism, Restriction Fragment Length; PPAR gamma; Proline | 2004 |
A region in the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+.
Topics: Alanine; Allosteric Site; Base Sequence; Calcium; Cell Line; Cell Membrane; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutamine; Humans; Hydrolysis; Immunoblotting; Ions; Isoleucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphatidylinositols; Proline; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Calcium-Sensing; Transfection | 2005 |
Nutrients released by gastric epithelial cells enhance Helicobacter pylori growth.
Topics: Alanine; Cells, Cultured; Culture Media; Epithelial Cells; Gastric Mucosa; Helicobacter pylori; Humans; Hypoxanthine; Iron; Mutation; Proline | 2004 |
Molecular characterization and diagnosis of Hb Crete [beta129(H7)Ala-->Pro].
Topics: Adult; Alanine; Amino Acid Substitution; Anemia, Macrocytic; DNA Mutational Analysis; Exons; Female; Globins; Hemoglobins, Abnormal; Heterozygote; Humans; Pedigree; Point Mutation; Proline | 2004 |
Peroxisome proliferator-activated receptor-gamma2 Pro12Ala and endothelial nitric oxide synthase-4a/b gene polymorphisms are not associated with hypertension in diabetes mellitus type 2.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Analysis of Variance; Blood Pressure; Chi-Square Distribution; Cohort Studies; Databases, Factual; Diabetes Mellitus, Type 2; Female; Gene Frequency; Heterozygote; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Polymorphism, Genetic; PPAR gamma; Proline; Retrospective Studies | 2005 |
A male twin infant with skull deformity and elevated neonatal 17-hydroxyprogesterone: a prismatic case of P450 oxidoreductase deficiency.
Topics: 17-alpha-Hydroxyprogesterone; Abnormalities, Multiple; Alanine; Amino Acid Substitution; Cytosine; Diagnosis, Differential; Diseases in Twins; Ear; Female; Guanine; Humans; Infant, Newborn; Male; Marfan Syndrome; NADPH-Ferrihemoprotein Reductase; Proline; Skull; Steroid Metabolism, Inborn Errors; Steroids | 2004 |
[Is obesity associated with a polymorphism Pro12Ala and Pro115Gln in the PPARgamma gene?].
Topics: Alanine; Body Mass Index; Case-Control Studies; Female; Gene Frequency; Glycine; Humans; Male; Obesity; Poland; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; PPAR gamma; Proline | 2004 |
Global transcriptional programs reveal a carbon source foraging strategy by Escherichia coli.
Topics: Acetic Acid; Alanine; Carbon; Computer Simulation; Escherichia coli; Gene Expression Profiling; Glucose; Glycerol; Models, Biological; Proline; Promoter Regions, Genetic; RNA, Ribosomal; Succinic Acid; Transcription, Genetic; Up-Regulation | 2005 |
Alcohol intake modulates the genetic association between HDL cholesterol and the PPARgamma2 Pro12Ala polymorphism.
Topics: Adult; Alanine; Alcohol Drinking; Alleles; Cholesterol, HDL; Female; Genotype; Humans; Male; Middle Aged; Phenotype; Polymorphism, Genetic; PPAR gamma; Proline | 2005 |
Tau phosphorylation increases in symptomatic mice overexpressing A30P alpha-synuclein.
Topics: Age Factors; Alanine; alpha-Synuclein; Amino Acid Substitution; Animals; Antibodies, Monoclonal; Blotting, Western; Brain; Disease Models, Animal; Female; Glial Fibrillary Acidic Protein; Humans; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinase Kinases; Movement Disorders; Mutation; Nerve Tissue Proteins; Neurons; Parkinson Disease; Phosphorylation; Proline; Synucleins; tau Proteins | 2005 |
Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice--a model of familial Parkinson's disease.
Topics: Alanine; alpha-Synuclein; Animals; Brain; Disease Models, Animal; Energy Metabolism; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondrial Proteins; Nerve Tissue Proteins; Oxidative Stress; Parkinson Disease; Proline; Synucleins | 2005 |
Identification and functional characterization of a novel low affinity aromatic-preferring amino acid transporter (arpAT). One of the few proteins silenced during primate evolution.
Topics: Alanine; Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Amino Acids; Amino Acids, Aromatic; Animals; Arginine; Biological Transport; Blotting, Northern; Blotting, Western; Cell Lineage; Chickens; Cloning, Molecular; Cysteine; Dimerization; DNA, Complementary; Dogs; Dose-Response Relationship, Drug; Evolution, Molecular; Gene Library; Gene Silencing; Glutamine; Glycine; HeLa Cells; Humans; In Situ Hybridization; Inhibitory Concentration 50; Intestine, Small; Kidney; Kinetics; Levodopa; Mice; Molecular Sequence Data; Open Reading Frames; Pan troglodytes; Phylogeny; Proline; Protein Binding; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Sodium; Transfection | 2005 |
Association of micropenis with Pro185Ala polymorphism of the gene for aryl hydrocarbon receptor repressor involved in dioxin signaling.
Topics: Adolescent; Alanine; Arginine; Basic Helix-Loop-Helix Transcription Factors; Case-Control Studies; Child; Child, Preschool; Congenital Abnormalities; Dioxins; Gene Frequency; Genetic Predisposition to Disease; Humans; Infant; Infant, Newborn; Lysine; Male; Penis; Polymorphism, Genetic; Proline; Receptors, Aryl Hydrocarbon; Repressor Proteins; Signal Transduction | 2005 |
Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population.
Topics: Adolescent; Adult; Alanine; Amino Acid Substitution; Case-Control Studies; Child; Diabetes Mellitus, Type 2; Female; France; Gene Frequency; Genetic Predisposition to Disease; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Phenotype; Polymorphism, Single Nucleotide; PPAR gamma; Proline; White People | 2005 |
An autosomal recessive limb girdle muscular dystrophy (LGMD2) with mild mental retardation is allelic to Walker-Warburg syndrome (WWS) caused by a mutation in the POMT1 gene.
Topics: Adolescent; Adult; Alanine; Alleles; Child; DNA Mutational Analysis; Female; Humans; Intellectual Disability; Male; Mannosyltransferases; Models, Molecular; Muscular Dystrophies, Limb-Girdle; Mutation; Phenotype; Polymorphism, Single Nucleotide; Proline; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2005 |
Analysis of separate and combined effects of common variation in KCNJ11 and PPARG on risk of type 2 diabetes.
Topics: Adult; Alanine; Amino Acid Substitution; Body Mass Index; Cohort Studies; Diabetes Mellitus, Type 2; Female; Genetic Variation; Glutamine; Humans; Lysine; Male; Middle Aged; Mutation, Missense; Potassium Channels, Inwardly Rectifying; PPAR gamma; Proline; Risk Factors | 2005 |
Preliminary crystallographic analysis of the Cks protein p13(suc1P90AP92A) from Schizosacharromyces pombe.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Cell Cycle; Cell Cycle Proteins; Crystallography, X-Ray; Dimerization; Electrophoresis, Polyacrylamide Gel; Genetic Vectors; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutation; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Fusion Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Sequence Homology, Amino Acid; Temperature; X-Ray Diffraction | 2005 |
Site-directed mutagenesis of proline 94 to alanine in amicyanin converts a true electron transfer reaction into one that is kinetically coupled.
Topics: Alanine; Bacterial Proteins; Copper; Electron Transport; Kinetics; Ligands; Metalloproteins; Models, Chemical; Mutagenesis, Site-Directed; Oxidation-Reduction; Paracoccus denitrificans; Proline; Thermodynamics | 2005 |
Aggregation of a slow-folding mutant of a beta-clam protein proceeds through a monomeric nucleus.
Topics: Alanine; Amino Acid Motifs; Amino Acid Substitution; Arsenic; Fluoresceins; Fluorescent Dyes; Kinetics; Microscopy, Fluorescence; Organometallic Compounds; Proline; Protein Folding; Protein Structure, Secondary; Receptors, Retinoic Acid; Spectrometry, Fluorescence; Time Factors | 2005 |
CYP3A43 Pro(340)Ala polymorphism and prostate cancer risk in African Americans and Caucasians.
Topics: Adult; Aged; Alanine; Arkansas; Aryl Hydrocarbon Hydroxylases; Black or African American; Genotype; Humans; Incidence; Male; Middle Aged; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Genetic; Proline; Prostatic Neoplasms; White People | 2005 |
Hydroxide and proton migration in aquaporins.
Topics: Alanine; Amino Acid Motifs; Aquaporins; Asparagine; Biological Transport; Biophysics; Cytoplasm; Escherichia coli; Escherichia coli Proteins; Hydrogen; Hydrogen Bonding; Hydroxides; Ions; Lipid Bilayers; Models, Chemical; Models, Molecular; Oxygen; Periplasm; Phosphatidylcholines; Proline; Protons; Static Electricity; Time Factors; Water | 2005 |
Characterization of a bifunctional PutA homologue from Bradyrhizobium japonicum and identification of an active site residue that modulates proline reduction of the flavin adenine dinucleotide cofactor.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Bradyrhizobium; Cell Membrane; Flavin-Adenine Dinucleotide; Kinetics; Ligands; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Phospholipids; Proline; Proline Oxidase; Sequence Alignment; Titrimetry | 2005 |
Cell-penetrating cis-gamma-amino-l-proline-derived peptides.
Topics: Alanine; Animals; Cell Membrane; Chlorocebus aethiops; Endocytosis; Flow Cytometry; Gene Products, tat; HeLa Cells; Humans; Leucine; Microscopy, Confocal; Microscopy, Fluorescence; Peptide Hydrolases; Peptides; Phenylalanine; Proline; Temperature | 2005 |
Inverse effects of the PPAR(gamma)2 Pro12Ala polymorphism on measures of adiposity over 15 years in African Americans and whites. The CARDIA study.
Topics: Adipose Tissue; Adolescent; Adult; Alanine; Base Sequence; Black People; Body Mass Index; Cohort Studies; DNA Primers; Exercise; Female; Humans; Male; Polymorphism, Genetic; PPAR gamma; Proline; White People | 2005 |
Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Age Factors; Alanine; alpha-Synuclein; Animals; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Humans; Immunohistochemistry; Insecticides; Mice; Mice, Transgenic; Neurons; Neurotoxins; Proline; Rotenone; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2006 |
Effect of multiple prolyl isomerization reactions on the stability and folding kinetics of the notch ankyrin domain: experiment and theory.
Topics: Alanine; Amino Acid Substitution; Ankyrin Repeat; Computer Simulation; Isomerism; Kinetics; Membrane Proteins; Models, Chemical; Proline; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Receptors, Notch | 2005 |
Structural and mutational analyses of the molecular interactions between the catalytic domain of factor XIa and the Kunitz protease inhibitor domain of protease nexin 2.
Topics: Alanine; Alzheimer Disease; Arginine; Binding Sites; Carrier Proteins; Catalytic Domain; Crystallography, X-Ray; Disulfides; DNA Mutational Analysis; Dose-Response Relationship, Drug; Factor XIa; Humans; Inhibitory Concentration 50; Kinetics; Lysine; Models, Molecular; Models, Statistical; Mutation; Partial Thromboplastin Time; Phenylalanine; Plasmids; Point Mutation; Proline; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Serine; Serine Proteinase Inhibitors; Structure-Activity Relationship; Thromboplastin; Time Factors; Vesicular Transport Proteins | 2005 |
Influence of the C161T but not Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma on colorectal cancer in an Indian population.
Topics: Adult; Aged; Alanine; Colonic Neoplasms; Colorectal Neoplasms; Cytosine; Gene Frequency; Haplotypes; Humans; India; Middle Aged; Polymorphism, Single Nucleotide; PPAR gamma; Proline; Rectal Neoplasms; Reference Values; Socioeconomic Factors; Thymopoietins | 2005 |
Two proline-rich peptides from pig (Sus scrofa) salivary glands generated by pre-secretory pathway underlying the action of a proteinase cleaving ProAla bonds.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Carbachol; Chromatography, High Pressure Liquid; Databases, Nucleic Acid; DNA, Complementary; Endopeptidases; Female; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Peptides; Phosphoserine; Pilocarpine; Proline; Proline-Rich Protein Domains; Saliva; Salivary Glands; Secretory Vesicles; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Sus scrofa | 2005 |
Mutation analysis of CLPTM 1 and PVRL 1 genes in patients with non-syndromic clefts of lip, alveolus and palate.
Topics: Alanine; Alveolar Process; Cell Adhesion Molecules; Child; Child, Preschool; Cleft Lip; Cleft Palate; Exons; Female; Glutamic Acid; Glycine; Humans; Immunoglobulins; Introns; Male; Membrane Proteins; Molecular Sequence Data; Mutation; Nectins; Proline; Receptors, Virus; Sequence Analysis, Protein; Sex Factors | 2005 |
An improved experimental system for determining small folding entropy changes resulting from proline to alanine substitutions.
Topics: Alanine; Amino Acid Substitution; Ankyrins; Chemistry, Physical; Entropy; Proline; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Proteins; Receptors, Notch; Solvents; Temperature | 2005 |
Chemical synthesis of the RGD-protein decorsin: Pro-->Ala replacement reduces protein thermostability.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Blood Platelets; Cell Adhesion Molecules; Circular Dichroism; Drug Stability; Hot Temperature; Humans; Inhibitory Concentration 50; Peptide Mapping; Platelet Aggregation Inhibitors; Proline; Protein Folding; Protein Structure, Tertiary; Proteins; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 2005 |
Collagen morphology is not associated with the Ala549Pro polymorphism of the COL1A2 gene.
Topics: Alanine; Collagen; Collagen Type I; DNA Mutational Analysis; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Peptides; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Proline; Skin; Vertebral Artery Dissection | 2005 |
Critical structure-function determinants within the N-terminal region of pulmonary surfactant protein SP-B.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Adsorption; Alanine; Amino Acid Sequence; Amino Acids; Circular Dichroism; Humans; Kinetics; Lipid Bilayers; Molecular Sequence Data; Peptides; Phosphatidylglycerols; Phospholipids; Pressure; Proline; Protein Structure, Secondary; Protein Structure, Tertiary; Pulmonary Surfactant-Associated Protein B; Structure-Activity Relationship; Time Factors; Tryptophan; Ultraviolet Rays | 2006 |
Effect of individual amino acids and glucose on activation and germination of Rhizopus oligosporus sporangiospores in tempe starter.
Topics: Alanine; Amino Acids; Arginine; Betaine; Colony Count, Microbial; Culture Media; Food Handling; Food Microbiology; Germination; Glucose; Glycine max; Isoleucine; Leucine; Phosphates; Proline; Rhizopus; Spores, Fungal | 2005 |
Chirality organization of ferrocenes bearing dipeptide chains of heterochiral sequence.
Topics: Alanine; Amino Acid Sequence; Crystallography, X-Ray; Dipeptides; Ferrous Compounds; Hydrogen Bonding; Metallocenes; Models, Molecular; Molecular Structure; Proline; Protein Structure, Secondary; Stereoisomerism | 2005 |
P61A mutation in the factor for inversion stimulation results in a thermostable dimeric intermediate.
Topics: Alanine; Amino Acid Substitution; Cross-Linking Reagents; Dimerization; Factor For Inversion Stimulation Protein; Glutaral; Hydrogen-Ion Concentration; Models, Molecular; Mutation; Proline; Protein Denaturation; Temperature; Urea | 2005 |
Thermodynamics and kinetics of formation of the alkaline state of a Lys 79-->Ala/Lys 73-->His variant of iso-1-cytochrome c.
Topics: Alanine; Cytochromes c; Guanidine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Mutagenesis, Site-Directed; Proline; Protein Denaturation; Saccharomyces cerevisiae Proteins; Static Electricity; Thermodynamics | 2005 |
Regulation of the catalytic activity of PTP1B: roles for cell adhesion, tyrosine residue 66, and proline residues 309 and 310.
Topics: Actins; Alanine; Amino Acid Substitution; Animals; Catalysis; Cell Adhesion; Cells, Cultured; Crk-Associated Substrate Protein; Cytoplasm; Endoplasmic Reticulum; Extracellular Matrix Proteins; Fibroblasts; Humans; Mice; Mutation; Phosphorylation; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; src-Family Kinases; Temperature; Tyrosine | 2005 |
Crystal structure of cone arrestin at 2.3A: evolution of receptor specificity.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Anura; Arginine; Arrestin; Arrestins; Asparagine; Biological Evolution; Cattle; Conserved Sequence; Crystallography, X-Ray; Electrophoretic Mobility Shift Assay; Escherichia coli; GTP-Binding Proteins; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutation; Phosphates; Proline; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Sensitivity and Specificity; Sequence Homology, Amino Acid; Signal Transduction; Spectrum Analysis, Raman; Urodela; Valine | 2005 |
Combining in silico tools and NMR data to validate protein-ligand structural models: application to matrix metalloproteinases.
Topics: Alanine; Binding Sites; Dipeptides; Glycine; Humans; Hydroxamic Acids; Ligands; Magnetic Resonance Spectroscopy; Matrix Metalloproteinase 1; Matrix Metalloproteinase 12; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Metalloendopeptidases; Models, Molecular; Molecular Conformation; Proline | 2005 |
Essential role for Pro21 in phospholamban for optimal inhibition of the Ca-ATPase.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Calcium-Binding Proteins; Calcium-Transporting ATPases; Models, Molecular; Molecular Sequence Data; Mutation; Proline; Protein Conformation | 2005 |
Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells.
Topics: Adenoviridae; Alanine; Animals; Arginine; Blotting, Western; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA-Binding Proteins; DNA, Complementary; Female; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Glycine; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Mutagenesis, Insertional; Neoplasm Invasiveness; Polymerase Chain Reaction; Proline; Proto-Oncogene Proteins; Repressor Proteins; Signal Transduction; Smad6 Protein; Smad7 Protein; Transforming Growth Factor beta; Up-Regulation | 2005 |
The in vivo effects of the Pro12Ala PPARgamma2 polymorphism on adipose tissue NEFA metabolism: the first use of the Oxford Biobank.
Topics: Adipose Tissue; Adult; Alanine; Amino Acid Substitution; Base Sequence; Blood Flow Velocity; Body Mass Index; Body Size; DNA Primers; Fatty Acids, Nonesterified; Female; Humans; Male; Middle Aged; Muscle, Skeletal; Polymorphism, Genetic; PPAR gamma; Proline; Registries | 2006 |
Molecular characterization of serine-, alanine-, and proline-rich proteins of Trypanosoma cruzi and their possible role in host cell infection.
Topics: Alanine; Amino Acid Sequence; Animals; Calcium; Cell Adhesion Molecules; Genome, Protozoan; HeLa Cells; Humans; Molecular Sequence Data; Peptides; Proline; Proline-Rich Protein Domains; Protozoan Proteins; Serine; Trypanosoma cruzi | 2006 |
Time dependent density functional theory modeling of chiroptical properties of small amino acids in solution.
Topics: Alanine; Computer Simulation; Glycine; Models, Chemical; Proline; Quantum Theory; Serine; Solutions; Time Factors | 2006 |
The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over 6 years and combines with the effect of the APM1 G-11391A single nucleotide polymorphism: the Data From an Epidemiological Study on the Insulin Resistance
Topics: Adiponectin; Adult; Alanine; Amino Acid Substitution; Diabetes Mellitus; Genotype; Humans; Hyperglycemia; Hyperinsulinism; Insulin Resistance; Middle Aged; Polymorphism, Single Nucleotide; PPAR gamma; Proline | 2006 |
Alanine check points in HNN and HN(C)N spectra.
Topics: Alanine; Amino Acids; Carbon Isotopes; Glycine; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Proline; Protein Folding | 2006 |
Abnormal glucose tolerance and insulin resistance in polycystic ovary syndrome amongst the Taiwanese population- not correlated with insulin receptor substrate-1 Gly972Arg/Ala513Pro polymorphism.
Topics: Adolescent; Adult; Alanine; Amino Acid Substitution; Arginine; Diabetes Mellitus; Female; Glucose Intolerance; Glucose Metabolism Disorders; Glucose Tolerance Test; Glycine; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; Phosphoproteins; Polycystic Ovary Syndrome; Polymorphism, Single Nucleotide; Proline; Prospective Studies; Taiwan | 2006 |
Association between the Pro12Ala variant of the peroxisome proliferator-activated receptor-gamma2 gene and increased 24-h diastolic blood pressure in obese patients with type II diabetes.
Topics: Alanine; Alleles; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Male; Middle Aged; Obesity; Polymorphism, Genetic; PPAR gamma; Proline; Time Factors | 2006 |
Role of genetic polymorphism peroxisome proliferator-activated receptor-gamma2 Pro12Ala on ethnic susceptibility to diabetes in South-Asian and Caucasian subjects: Evidence for heterogeneity.
Topics: Absorptiometry, Photon; Adult; Aged; Alanine; Amino Acid Substitution; Asian People; DNA Primers; Female; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Molecular Sequence Data; Polymerase Chain Reaction; Polymorphism, Genetic; PPAR gamma; Proline; Reference Values; White People | 2006 |
The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on glucose/insulin metabolism interact with prenatal exposure to famine.
Topics: Aged; Alanine; Blood Glucose; DNA Primers; Female; Humans; Insulin; Male; Maternal Age; Netherlands; Polymorphism, Genetic; PPAR gamma; Pregnancy; Prenatal Exposure Delayed Effects; Proline; Starvation | 2006 |
Biocompatibility of elastin-like polymer poly(VPAVG) microparticles: in vitro and in vivo studies.
Topics: Alanine; Amino Acid Sequence; Animals; Biocompatible Materials; Cell Survival; Conjunctivitis; Edema; Elastin; Glycine; Macrophages, Peritoneal; Mice; Microscopy, Electron, Scanning; Molecular Weight; Peptides; Proline; Valine; Vitreous Body; X-Ray Diffraction | 2006 |
The influence of the Pro12Ala mutation of PPARgamma2 receptor gene on beta-cells restoration and insulin resistance in type 2 diabetes with hypertension.
Topics: Alanine; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Hypertension; Insulin Resistance; Insulin-Secreting Cells; Mutation; PPAR gamma; Proline | 2005 |
The planar conformation of a strained proline ring: a QM/MM study.
Topics: Alanine; Binding Sites; Computational Biology; Crystallography, X-Ray; Glutamic Acid; Models, Molecular; Molecular Structure; Proline; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Thermodynamics; Triose-Phosphate Isomerase; Tyrosine | 2006 |
Peroxisome proliferator-activated receptor-gamma polymorphism, body mass and prostate cancer risk: evidence for gene-environment interaction.
Topics: Adult; Aged; Alanine; Body Mass Index; Case-Control Studies; Genotype; Humans; Insulin; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; PPAR gamma; Predictive Value of Tests; Proline; Prostatic Neoplasms; Waist-Hip Ratio | 2006 |
The absolute structural requirement for a proline in the P3'-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aprotinin; Cattle; Conserved Sequence; Helianthus; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Plant Proteins; Proline; Serine Proteinase Inhibitors; Structure-Activity Relationship; Trypsin Inhibitor, Bowman-Birk Soybean | 2006 |
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma gene in women with polycystic ovary syndrome.
Topics: Adult; Alanine; Androstenedione; Blood Glucose; C-Peptide; Dehydroepiandrosterone Sulfate; Female; Follicle Stimulating Hormone; Glucose Tolerance Test; Heterozygote; Homeostasis; Humans; Insulin; Insulin Resistance; Luteinizing Hormone; Polycystic Ovary Syndrome; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; PPAR gamma; Proline; Testosterone | 2006 |
[Influence of polymorphism pro12Ala of PPARgamma gene on endothelium destruction in patients with diabetes mellitus t. 2].
Topics: Adult; Aged; Alanine; Amino Acid Substitution; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Endothelium; Female; Genetic Predisposition to Disease; Humans; Hypertension; Male; Middle Aged; Polymorphism, Genetic; PPAR gamma; Proline; Transcription Factors | 2005 |
Association between Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma 2 and myocardial infarction in the Chinese Han population.
Topics: Aged; Alanine; Asian People; Electrophoresis; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Myocardial Infarction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; PPAR gamma; Proline | 2006 |
Inhibition of protein aggregation in vitro and in vivo by a natural osmoprotectant.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Escherichia coli; Exons; Fluoresceins; Fluorescent Dyes; Glutamine; Humans; Huntingtin Protein; In Vitro Techniques; Kinetics; Microscopy, Fluorescence; Models, Biological; Nerve Tissue Proteins; Nuclear Proteins; Organometallic Compounds; Osmolar Concentration; Osmotic Pressure; Proline; Protein Folding; Protein Structure, Secondary; Proteins; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Solubility; Spectrometry, Fluorescence | 2006 |
PPAR-gamma2 Pro12Ala variant, insulin resistance and plasma long-chain polyunsaturated fatty acids in childhood obesity.
Topics: Alanine; Child; Fatty Acids, Unsaturated; Female; Gene Frequency; Humans; Insulin Resistance; Male; Obesity; Phospholipids; Polymorphism, Genetic; PPAR gamma; Proline | 2006 |
Peroxisome proliferator-activated [corrected] receptor-gamma2 [corrected] Pro12Ala, interaction with alcohol intake and NSAID use, in relation to risk of breast cancer in a prospective study of Danes.
Topics: Alanine; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Base Sequence; Breast Neoplasms; Case-Control Studies; DNA Primers; Female; Humans; Polymorphism, Genetic; PPAR gamma; Proline; Prospective Studies | 2007 |
The P1812A and P25T BRCA1 and the 5164del4 BRCA2 mutations: occurrence in high-risk non-Ashkenazi Jews.
Topics: Adult; Aged; Alanine; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; BRCA1 Protein; BRCA2 Protein; Female; Genetic Predisposition to Disease; Humans; Jews; Male; Middle Aged; Molecular Sequence Data; Pedigree; Proline; Sequence Deletion; Threonine | 2006 |
The organic osmolytes betaine and proline are transported by a shared system in early preimplantation mouse embryos.
Topics: Alanine; Amino Acids; Animals; Betaine; Biological Transport; Blastocyst; Carrier Proteins; Chlorides; Dose-Response Relationship, Drug; Embryo Culture Techniques; Fallopian Tubes; Female; Kinetics; Mice; Proline; Sarcosine; Sodium; Time Factors; Water-Electrolyte Balance | 2007 |
The conformation of cyclo(-D-Pro-Ala4-) as a model for cyclic pentapeptides of the DL4 type.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Computer Simulation; Hydrogen Bonding; Isotope Labeling; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptides, Cyclic; Proline; Protein Conformation; Solutions; Time Factors | 2006 |
Conformational preferences of non-prolyl and prolyl residues.
Topics: Alanine; Dipeptides; Hydrogen Bonding; Isomerism; Molecular Conformation; Proline; Solvents | 2006 |
PPAR-gamma Pro12Ala genotype and risk of cognitive decline in elders.
Topics: Aged; Aging; Alanine; Black People; Cognition Disorders; Female; Genotype; Humans; Longitudinal Studies; Male; Mental Status Schedule; Neuropsychological Tests; PPAR gamma; Proline; Retrospective Studies; Risk; White People | 2008 |
Peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism is associated with reduced risk for ischemic stroke with type 2 diabetes.
Topics: Aged; Alanine; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Middle Aged; Multivariate Analysis; Peroxisome Proliferator-Activated Receptors; Polymorphism, Genetic; Proline; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stroke | 2006 |
Functional role of the conserved active site proline of triosephosphate isomerase.
Topics: Alanine; Animals; Binding Sites; Conserved Sequence; Crystallography, X-Ray; Mutagenesis, Site-Directed; Proline; Protozoan Proteins; Triose-Phosphate Isomerase; Trypanosoma | 2006 |
Aquaporin-11 containing a divergent NPA motif has normal water channel activity.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Aquaporins; Asparagine; Baculoviridae; Cells, Cultured; Liposomes; Mice; Molecular Sequence Data; Proline; Recombinant Proteins; Spodoptera; Transfection; Water | 2007 |
The Pro12Ala polymorphism in PPARgamma2 gene affects lipid parameters in Greek primary school children: A case of gene-to-gender interaction.
Topics: Alanine; Alleles; Body Mass Index; Child; Cohort Studies; Female; Greece; Heterozygote; Homozygote; Humans; Lipids; Male; Polymorphism, Genetic; PPAR gamma; Proline; Sex Factors | 2007 |
Polypeptide motions are dominated by peptide group oscillations resulting from dihedral angle correlations between nearest neighbors.
Topics: Alanine; Computer Simulation; Glycine; Models, Molecular; Molecular Conformation; Motion; Peptides; Proline; Protein Folding | 2007 |
Pro12Ala polymorphism of the PPARgamma2 locus modulates the relationship between energy intake and body weight in type 2 diabetic patients.
Topics: Adult; Aged; Alanine; Amino Acid Substitution; Body Mass Index; Creatinine; Diabetes Mellitus, Type 2; Diet, Diabetic; Energy Metabolism; Feeding Behavior; Female; Genetic Carrier Screening; Genetic Variation; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; PPAR gamma; Proline; Weight Gain | 2007 |
Cleavage after residue Ala352 in the C-terminal extension is an early step in the maturation of the D1 subunit of Photosystem II in Synechocystis PCC 6803.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Mass Spectrometry; Molecular Sequence Data; Photosystem II Protein Complex; Proline; Protein Subunits; Synechocystis | 2007 |
Cold exposure and associated metabolic changes in adult tropical beetles exposed to fluctuating thermal regimes.
Topics: Acclimatization; Alanine; Amino Acids; Amino Acids, Essential; Animals; Arginine; Body Temperature; Cold Temperature; Glucose; Glutamic Acid; Glutamine; Glycerol; Inositol; Lysine; Proline; Ribitol; Sorbitol; Survival Analysis; Temperature; Tenebrio; Threonine; Trehalose; Tropical Climate; Valine | 2007 |
Lack of association between serum adiponectin levels and the Pro12Ala polymorphism in Asian Indians.
Topics: Adiponectin; Adult; Alanine; Asian People; Diabetes Mellitus; Epidemiologic Studies; Female; Genotype; Glucose Tolerance Test; Humans; India; Male; Middle Aged; Polymorphism, Genetic; PPAR gamma; Proline | 2007 |
Amino acid and codon use: in two influenza viruses and three hosts.
Topics: Alanine; Amino Acids; Animals; Chickens; Codon; Humans; Influenza A virus; Influenza B virus; Leucine; Proline; Swine | 2007 |
Leisure-time physical activity is associated with the metabolic syndrome in type 1 diabetes: effect of the PPARgamma Pro12Ala polymorphism: the FinnDiane Study.
Topics: Adult; Alanine; Amino Acid Substitution; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Humans; Leisure Activities; Metabolic Syndrome; Physical Fitness; Polymorphism, Genetic; PPAR gamma; Prevalence; Proline | 2007 |
Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism is associated with the susceptibility to ischemic stroke in Taeeumin classified by Sasang medicine.
Topics: Aged; Alanine; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Medicine, East Asian Traditional; Middle Aged; Philosophy, Medical; Polymorphism, Genetic; PPAR gamma; Proline; Stroke | 2007 |
The Pro12Ala polymorphism in PPARG2 increases the effectiveness of primary prevention of cardiovascular disease by a lifestyle intervention.
Topics: Alanine; Amino Acid Substitution; C-Reactive Protein; Cardiovascular Diseases; Dietary Carbohydrates; Dietary Fats; Life Style; Polymerase Chain Reaction; PPAR gamma; Proline; Vasodilation | 2007 |
Effects of a mutation in the TM2-TM3 linker region of the glycine receptor alpha1 subunit on gating and allosteric modulation.
Topics: Alanine; Allosteric Regulation; Amino Acid Sequence; Anesthetics, Inhalation; Animals; Binding Sites; Cysteine; Ethanol; Female; In Vitro Techniques; Ion Channel Gating; Lysine; Molecular Sequence Data; Mutation; Oocytes; Proline; Protein Structure, Tertiary; Protein Subunits; Receptors, Glycine; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Sequence Alignment; Signal Transduction; Xenopus laevis | 2007 |
An analysis of peroxisome proliferator-activated receptor gamma (PPAR-gamma 2) Pro12Ala polymorphism distribution and prevalence of type 2 diabetes mellitus (T2DM) in world populations in relation to dietary habits.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Benin; Climate; Diabetes Mellitus, Type 2; Dietary Fats; Ecuador; Environment; Ethiopia; Feeding Behavior; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Italy; Male; Middle Aged; Polymorphism, Genetic; PPAR gamma; Prevalence; Proline | 2007 |
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPARgamma-2) gene is associated with greater insulin sensitivity and decreased risk of type 2 diabetes in an Iranian population.
Topics: Alanine; Base Sequence; Diabetes Mellitus, Type 2; DNA Primers; Genetic Predisposition to Disease; Humans; Insulin Resistance; Iran; Polymorphism, Genetic; PPAR gamma; Proline | 2007 |
Development of an electrolytic system for non-Kolbe electrolysis based on the acid-base reaction between carboxylic acids as a substrate and solid-supported bases.
Topics: Alanine; Carboxylic Acids; Electrolysis; Methanol; Piperidines; Proline; Silica Gel; Silicon Dioxide | 2007 |
Agonist-dependent consequences of proline to alanine substitution in the transmembrane helices of the calcitonin receptor.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amyloid; Animals; Blotting, Western; Calcitonin; Cells, Cultured; Cyclic AMP; DNA; Enzyme-Linked Immunosorbent Assay; Humans; Intracellular Signaling Peptides and Proteins; Islet Amyloid Polypeptide; Membrane Potentials; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Radioligand Assay; Receptor Activity-Modifying Proteins; Receptors, Calcitonin; Salmon; Transfection | 2007 |
Effect of selected Ser/Ala and Xaa/Pro mutations on the stability and catalytic properties of a cold adapted subtilisin-like serine proteinase.
Topics: Alanine; Amino Acids; Catalysis; Cold Temperature; Enzyme Stability; Kinetics; Models, Molecular; Mutation; Proline; Protein Structure, Tertiary; Serine; Subtilisin; Temperature; Vibrio | 2007 |
Differential inhibition of CYP17A1 and CYP21A2 activities by the P450 oxidoreductase mutant A287P.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Humans; Mice; Molecular Sequence Data; NADPH-Ferrihemoprotein Reductase; Proline; Rabbits; Rats; Steroid 17-alpha-Hydroxylase; Steroid 21-Hydroxylase | 2007 |
A novel mutation in human ether-a-go-go-related gene, alanine to proline at position 490, found in a large family with autosomal dominant long QT syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Genes, Dominant; Humans; Male; Middle Aged; Mutation, Missense; Pedigree; Proline; Romano-Ward Syndrome | 2007 |
Anharmonic effects in IR, Raman, and Raman optical activity spectra of alanine and proline zwitterions.
Topics: Alanine; Computer Simulation; Models, Molecular; Molecular Structure; Proline; Quantum Theory; Spectrophotometry, Infrared; Spectrum Analysis, Raman | 2007 |
Interaction of thrombin with PAR1 and PAR4 at the thrombin cleavage site.
Topics: Alanine; Binding Sites; Kinetics; Leucine; Proline; Protein Conformation; Protein Structure, Tertiary; Receptor, PAR-1; Receptors, Thrombin; Recombinant Fusion Proteins; Thrombin | 2007 |
Role of non-phosphorylated activation loop residues in determining ERK2 dephosphorylation, activity, and subcellular localization.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Cricetulus; Green Fluorescent Proteins; Mitogen-Activated Protein Kinase 1; Molecular Sequence Data; Phosphorylation; Proline; Signal Transduction | 2007 |
Accurate charge density of the tripeptide Ala-Pro-Ala with the maximum entropy method (MEM): influence of data resolution.
Topics: Alanine; Crystallography, X-Ray; Data Interpretation, Statistical; Electrons; Entropy; Hydrogen Bonding; Models, Statistical; Molecular Conformation; Molecular Structure; Peptides; Proline; Protein Conformation; Software; Temperature; X-Ray Diffraction | 2007 |
Novel mutations in the FOXC1 gene in Japanese patients with Axenfeld-Rieger syndrome.
Topics: Abnormalities, Multiple; Adult; Alanine; Anterior Eye Segment; Asian People; Base Sequence; Child, Preschool; Eye Abnormalities; Female; Forkhead Transcription Factors; Frameshift Mutation; Gene Deletion; Genes, Dominant; Humans; Mutation, Missense; Pedigree; Phenotype; Proline; Protein Structure, Tertiary; Syndrome | 2007 |
The Pro12Ala polymorphism of the PPAR-gamma2 gene affects associations of fish intake and marine n-3 fatty acids with glucose metabolism.
Topics: Alanine; Alleles; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diet Records; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Nonesterified; Fatty Acids, Omega-3; Female; Genotype; Heterozygote; Homozygote; Humans; Insulin; Insulin Resistance; Lipids; Male; Middle Aged; Polymorphism, Genetic; PPAR gamma; Proline; Sex Factors | 2008 |
Entrapped energy in chiral solutions: quantification and information capacity.
Topics: Alanine; Hot Temperature; Proline; Solutions; Stereoisomerism | 2007 |
In vitro effect of PPAR-gamma2 Pro12Ala polymorphism on the deposition of Alzheimer's amyloid-beta peptides.
Topics: Alanine; Amyloid beta-Peptides; Animals; Cell Line, Transformed; Cloning, Molecular; Enzyme-Linked Immunosorbent Assay; Humans; Luciferases; Mice; Peptide Fragments; Polymorphism, Genetic; PPAR gamma; Proline; Transfection | 2007 |
Effect of the Ala12 allele in the PPARgamma-2 gene on the relationship between birth weight and body composition in adolescents: the AVENA study.
Topics: Adolescent; Alanine; Birth Weight; Body Composition; Body Fat Distribution; Body Height; Body Mass Index; Body Weight; Cross-Sectional Studies; Female; Gene Frequency; Genotype; Humans; Male; PPAR gamma; Proline; Skinfold Thickness; Spain | 2007 |
Lack of association between the Pro12Ala polymorphism of the PPAR-gamma 2 gene and type 2 diabetes mellitus in the Qatari consanguineous population.
Topics: Adult; Alanine; Amino Acid Substitution; Body Mass Index; Consanguinity; Diabetes Mellitus, Type 2; DNA; Female; Humans; Male; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; PPAR gamma; Proline; Qatar; Reference Values | 2008 |
Intrathecal injection of glutamate receptor antagonists/agonist selectively attenuated rat pain-related behaviors induced by the venom of scorpion Buthus martensi Karsch.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Injections, Spinal; Male; Pain; Proline; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Scorpion Venoms | 2007 |
Differential colchicine-binding across eukaryotic families: the role of highly conserved Pro268beta and Ala248beta residues in animal tubulin.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Colchicine; Conserved Sequence; Crystallography, X-Ray; Molecular Sequence Data; Mutation; Proline; Protein Conformation; Tubulin | 2007 |
Mapping of a region of Ebola virus VP40 that is important in the production of virus-like particles.
Topics: Alanine; Amino Acid Sequence; Cell Line; Ebolavirus; Glycine; Humans; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Proline; Recombinant Proteins; Viral Matrix Proteins; Virus Replication | 2007 |
Disruption of dopamine homeostasis underlies selective neurodegeneration mediated by alpha-synuclein.
Topics: Alanine; alpha-Methyltyrosine; alpha-Synuclein; Animals; Animals, Genetically Modified; Cells, Cultured; Dopamine; Drosophila; Embryo, Nonmammalian; Enzyme Inhibitors; Glutathione; Green Fluorescent Proteins; Homeostasis; Humans; Indoles; Mutation; Nerve Degeneration; Proline; Receptors, Dopamine D1; Time Factors; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins | 2007 |
The association of Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma gene with serum osteoprotegerin levels in healthy Korean women.
Topics: Alanine; Amino Acid Substitution; Asian People; Bone and Bones; Bone Density; Enzyme-Linked Immunosorbent Assay; Female; Gene Frequency; Humans; Korea; Middle Aged; Mutation; Osteoprotegerin; Polymorphism, Genetic; PPAR gamma; Proline | 2007 |
The varitint-waddler (Va) deafness mutation in TRPML3 generates constitutive, inward rectifying currents and causes cell degeneration.
Topics: Alanine; Alleles; Animals; Cell Line; Electrophysiology; Epithelium; Gadolinium; Hair Cells, Auditory; Humans; Mice; Microscopy, Fluorescence; Models, Biological; Mutation; Proline; Transient Receptor Potential Channels; TRPM Cation Channels | 2008 |
Peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism, cod liver oil and risk of type 1 diabetes.
Topics: Alanine; Amino Acid Substitution; Case-Control Studies; Child; Cod Liver Oil; Diabetes Mellitus, Type 1; Fatty Acids, Omega-3; Humans; Norway; Polymorphism, Single Nucleotide; PPAR gamma; Proline; Registries; Risk Factors | 2008 |
Analysis of the thermodynamics of binding of an SH3 domain to proline-rich peptides using a chimeric fusion protein.
Topics: Alanine; Amino Acid Sequence; Calorimetry, Differential Scanning; Circular Dichroism; Hot Temperature; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutant Proteins; Mutation; Peptides; Proline; Protein Binding; Protein Folding; Protons; Recombinant Fusion Proteins; Sequence Alignment; Spectrin; Spectrometry, Fluorescence; src Homology Domains; Thermodynamics | 2008 |
Stabilization of beta-propeller phytase by introducing Xaa-->Pro and Gly-->Ala substitutions at consensus positions.
Topics: 6-Phytase; Alanine; Amino Acid Sequence; Amino Acid Substitution; Bacillus; Consensus Sequence; Glycine; Molecular Sequence Data; Proline; Protein Structure, Tertiary; Sequence Alignment | 2008 |
PPARgamma mRNA expression is reduced in peripheral blood mononuclear cells after fat overload in patients with metabolic syndrome.
Topics: Alanine; Body Mass Index; Dietary Fats; Gene Expression; Glutathione; Humans; Insulin Resistance; Leukocytes, Mononuclear; Lipid Peroxidation; Metabolic Syndrome; NF-kappa B; Oxidative Stress; Polymerase Chain Reaction; Polymorphism, Genetic; PPAR gamma; Proline; Protein Carbonylation; RNA, Messenger; Triglycerides | 2008 |
The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma2 gene is associated with plasma levels of soluble RAGE (Receptor for Advanced Glycation Endproducts) and the presence of peripheral arterial disease.
Topics: Aged; Alanine; Alleles; Biomarkers; Case-Control Studies; Confidence Intervals; DNA; Female; Genotype; Humans; Italy; Logistic Models; Male; Middle Aged; Odds Ratio; Peripheral Vascular Diseases; Polymerase Chain Reaction; Polymorphism, Genetic; PPAR gamma; Proline; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors | 2008 |
Molecular interactions of alanine-rich and proline-rich regions of cell surface protein antigen c in Streptococcus mutans.
Topics: Alanine; Antibody Affinity; Antigens, Bacterial; Antigens, Surface; Bacterial Adhesion; Bacterial Proteins; Coated Materials, Biocompatible; Durapatite; Electrophoresis, Polyacrylamide Gel; Epitopes; Humans; Mutation; Peptides; Proline; Proline-Rich Protein Domains; Recombinant Proteins; Salivary Proteins and Peptides; Streptococcus mutans | 2008 |
Interaction between PPARG Pro12Ala and ADIPOQ G276T concerning cholesterol levels in childhood obesity.
Topics: Adiponectin; Adolescent; Alanine; Body Mass Index; Child; Cholesterol; Cross-Sectional Studies; Female; Gene Frequency; Genetic Variation; Genotype; Heterozygote; Homozygote; Humans; Insulin Resistance; Lipids; Male; Obesity; Polymorphism, Genetic; PPAR gamma; Proline; Risk Assessment; Risk Factors | 2009 |
Electrospray ionization-ion trap mass spectrometry study of PQAAPro and PQProAA mimetic derivatives of the antimalarial primaquine.
Topics: Alanine; Amino Acids; Antimalarials; Imidazolidines; Molecular Structure; Primaquine; Proline; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2008 |
[Association of the Pro12Ala and C1431T polymorphism of the PPAR gamma2 gene and their haplotypes with obesity and type 2 diabetes].
Topics: Alanine; Amino Acid Substitution; Asian People; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; Haplotypes; Humans; Male; Middle Aged; Obesity; Polymorphism, Genetic; PPAR gamma; Proline; Triglycerides | 2008 |
The orphan transporter Rxt1/NTT4 (SLC6A17) functions as a synaptic vesicle amino acid transporter selective for proline, glycine, leucine, and alanine.
Topics: Alanine; Amino Acid Transport Systems; Amino Acids; Animals; CHO Cells; Cricetinae; Cricetulus; Glycine; Humans; In Vitro Techniques; Leucine; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; PC12 Cells; Proline; Rats; RNA, Small Interfering; Synaptic Vesicles | 2008 |
An investigation of protonation sites and conformations of protonated amino acids by IRMPD spectroscopy.
Topics: Alanine; Amino Acids; Glycine; Hydrogen Bonding; Molecular Conformation; Proline; Protons; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Thermodynamics | 2008 |
Lincomycin, rational selection of high producing strain and improved fermentation by amino acids supplementation.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Biomedical Engineering; Bioreactors; Fermentation; Levodopa; Lincomycin; Mutation; Proline; Pyruvate Kinase; Streptomyces; Tyrosine | 2009 |
Association of the PPARgamma gene polymorphism Pro12Ala with delayed onset of multiple sclerosis.
Topics: Adolescent; Adult; Age of Onset; Aged; Alanine; Case-Control Studies; Community Health Planning; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Middle Aged; Multiple Sclerosis; Polymorphism, Genetic; PPAR gamma; Proline; Young Adult | 2009 |
Aging and alpha-synuclein affect synaptic plasticity in the dentate gyrus.
Topics: Aging; Alanine; alpha-Synuclein; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Dentate Gyrus; Electric Stimulation; Escape Reaction; Excitatory Postsynaptic Potentials; Humans; Locomotion; Mice; Mice, Transgenic; Mutation; Neuronal Plasticity; Perforant Pathway; Proline; Reaction Time; Synapses; Time Factors | 2009 |
Sequence-specific unusual (1-->2)-type helical turns in alpha/beta-hybrid peptides.
Topics: Alanine; Amino Acid Sequence; Aminoisobutyric Acids; Crystallography, X-Ray; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; ortho-Aminobenzoates; Peptides; Proline; Protein Structure, Secondary; Structure-Activity Relationship | 2008 |
Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (PPARgamma) gene in inflammatory bowel disease.
Topics: Adult; Alanine; Case-Control Studies; Colitis, Ulcerative; Crohn Disease; Female; Humans; Male; Mutation, Missense; Polymorphism, Genetic; PPAR gamma; Proline; Turkey | 2008 |
Effect of a carboxyl group on the chemiluminescent reaction of tris(2,2'-bipyridine)ruthenium(III) with aliphatic amines.
Topics: 2,2'-Dipyridyl; Alanine; Amines; Humans; Hydroxyproline; Luminescent Measurements; Pipecolic Acids; Proline; Ruthenium; Sarcosine | 2009 |
Breast-feeding modifies the association of PPARgamma2 polymorphism Pro12Ala with growth in early life: the Generation R Study.
Topics: Alanine; Amino Acid Substitution; Body Weight; Breast Feeding; Child; Diabetes Mellitus, Type 2; Female; Fetal Development; Genotype; Growth; Heterozygote; Humans; Infant; Infant, Newborn; Polymorphism, Genetic; PPAR gamma; Pregnancy; Pregnancy Trimester, Second; Proline | 2009 |
Phosphorylation of highly conserved neurofilament medium KSP repeats is not required for myelin-dependent radial axonal growth.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Axons; Conserved Sequence; Gene Knock-In Techniques; Lysine; Mice; Mice, Neurologic Mutants; Molecular Sequence Data; Myelin Sheath; Nerve Crush; Neural Pathways; Neurofilament Proteins; Phosphorylation; Proline; Repetitive Sequences, Amino Acid; Serine | 2009 |
Helix 3 is necessary and sufficient for prion protein's anti-Bax function.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cells, Cultured; Cytoprotection; Humans; Mice; Neoplasms; Nerve Degeneration; Prion Diseases; Proline; Protein Structure, Secondary; PrPC Proteins | 2009 |
PPAR gamma variant influences angiographic outcome and 10-year cardiovascular risk in male symptomatic coronary artery disease patients.
Topics: Alanine; Amino Acid Substitution; Blood Pressure; Coronary Disease; Genetic Variation; Genotype; Humans; Hypertension; Male; Middle Aged; PPAR gamma; Proline; Proportional Hazards Models; Radiography | 2009 |
Ab initio studies of receptor interactions with AMPA ((S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl) propionic acid) and kainic acid (2S-(2 alpha, 3 beta, 4 beta))-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Behavior; Brain; Excitatory Amino Acid Agonists; Humans; Kainic Acid; Molecular Sequence Data; Mutation; Proline; Quantum Theory; Receptors, AMPA; Thermodynamics; Tyrosine | 2009 |
Changes in adult olfactory bulb neurogenesis in mice expressing the A30P mutant form of alpha-synuclein.
Topics: Alanine; alpha-Synuclein; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Death; Cell Proliferation; Doublecortin Domain Proteins; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Mutation; Neurogenesis; Neurons; Neuropeptides; Olfactory Bulb; Proliferating Cell Nuclear Antigen; Proline | 2009 |
A thorough study on the use of quantitative 1H NMR in Rioja red wine fermentation processes.
Topics: Acetic Acid; Alanine; Ethanol; Fermentation; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Proline; Succinic Acid; Wine | 2009 |
The Pro12Ala polymorphism of the PPARgamma2 gene is associated with hepatic glucose uptake during hyperinsulinemia in subjects with type 2 diabetes mellitus.
Topics: Adult; Alanine; Diabetes Mellitus, Type 2; Female; Humans; Hyperinsulinism; Male; Polymorphism, Genetic; PPAR gamma; Proline | 2009 |
The active form of human aryl hydrocarbon receptor (AHR) repressor lacks exon 8, and its Pro 185 and Ala 185 variants repress both AHR and hypoxia-inducible factor.
Topics: Alanine; Amino Acid Sequence; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Line; Exons; Gene Expression Regulation; Humans; Hypoxia-Inducible Factor 1; Mice; Molecular Sequence Data; Pregnane X Receptor; Proline; Promoter Regions, Genetic; Protein Isoforms; Receptors, Aryl Hydrocarbon; Receptors, Steroid; Recombinant Fusion Proteins; Repressor Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Tissue Distribution | 2009 |
PPARgamma Pro12Ala polymorphism and risk of acute coronary syndrome in a prospective study of Danes.
Topics: Acute Coronary Syndrome; Aged; Alanine; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cohort Studies; Denmark; Female; Genotype; Humans; Male; Middle Aged; Polymorphism, Genetic; PPAR gamma; Proline; Prospective Studies; Risk Factors; Sex Factors; Smoking | 2009 |
The proline 12 alanine substitution in the PPARgamma2 gene is associated with increased extent of coronary artery disease in men.
Topics: Age Factors; Aged; Alanine; Alleles; Angiography; Coronary Artery Disease; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Insulin Resistance; Male; Middle Aged; Polymorphism, Genetic; PPAR gamma; Proline; Protein Isoforms; Regression Analysis | 2009 |
Amino acids in the rat intestinal lumen regulate their own absorption from a distant intestinal site.
Topics: Alanine; Animals; Biological Transport; Calcitonin Gene-Related Peptide; Capsaicin; Enteric Nervous System; Feedback, Physiological; Female; Ileum; Infusions, Intravenous; Intestinal Absorption; Intestinal Mucosa; Jejunum; Kinetics; Neurons, Afferent; Proline; Rats; Rats, Sprague-Dawley; Reflex; Sodium; Tetrodotoxin; Vagotomy; Vagus Nerve | 2009 |
Polymorphism of Pro12Ala in the peroxisome proliferator-activated receptor gamma2 gene in Iranian diabetic and obese subjects.
Topics: Alanine; Asian People; Body Mass Index; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Iran; Logistic Models; Male; Obesity; Odds Ratio; Polymorphism, Single Nucleotide; PPAR gamma; Proline; Risk Assessment; Risk Factors | 2009 |
Synthesis and evaluation of new endomorphin analogues modified at the Pro(2) residue.
Topics: Alanine; Animals; Azetidinecarboxylic Acid; Binding Sites; Brain; Cell Membrane; Inhibitory Concentration 50; Kinetics; Models, Chemical; Oligopeptides; Peptides; Proline; Rats; Receptors, Opioid, mu | 2009 |
The association of olanzapine-induced weight gain with peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism in patients with schizophrenia.
Topics: Adult; Alanine; Antipsychotic Agents; Base Sequence; Benzodiazepines; DNA Primers; Humans; Middle Aged; Olanzapine; PPAR gamma; Proline; Schizophrenia; Weight Gain | 2009 |
Network of hydrogen bonds in Pro-Ala-Pro and Pro-Phe-Pro diamides: a first principles study of Ala-->Phe point mutation in proline environment.
Topics: Alanine; Diamide; Hydrogen Bonding; Oligopeptides; Phenylalanine; Point Mutation; Proline | 2009 |
A second case of Hb Fontainebleau [alpha21(B2)Ala-->Pro] in an individual with microcytosis.
Topics: Adult; Alanine; Amino Acid Substitution; Anemia; Erythrocyte Indices; Hemoglobins, Abnormal; Humans; Male; Proline; Spectrometry, Mass, Electrospray Ionization | 2009 |
Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma-2 gene on obesity risk and leptin levels in a Tunisian population.
Topics: Alanine; Case-Control Studies; Female; Humans; Leptin; Male; Obesity; PPAR gamma; Proline; Risk Factors; Sex Factors; Tunisia | 2009 |
Pro12Ala polymorphism in PPARgamma2 associated with depression in Chinese nonagenarians/centenarians.
Topics: Aged, 80 and over; Alanine; China; Depression; Female; Gene Frequency; Humans; Logistic Models; Male; Polymorphism, Genetic; PPAR gamma; Prevalence; Proline | 2009 |
Mmp-20 and Klk4 cleavage site preferences for amelogenin sequences.
Topics: Alanine; Amelogenesis; Amelogenin; Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dental Enamel; Dental Enamel Proteins; Electrophoresis, Polyacrylamide Gel; Histidine; Kallikreins; Matrix Metalloproteinase 20; Proline; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Swine; Tandem Mass Spectrometry; Tryptophan | 2009 |
The PPAR-gamma Pro12Ala polymorphism associates with weight gain during GH-treatment in short children born small for gestational age.
Topics: Alanine; Body Height; Child; Child, Preschool; Female; Growth Disorders; Growth Hormone; Human Growth Hormone; Humans; Infant, Newborn; Infant, Small for Gestational Age; Male; Polymorphism, Genetic; PPAR gamma; Proline; Weight Gain | 2010 |
Molecular consequences of genetic variations in the glutathione peroxidase 1 selenoenzyme.
Topics: Alanine; Alleles; Antioxidants; Breast Neoplasms; Codon; DNA Damage; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genotype; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Leucine; Lymphocytes; Mutagenesis; Polymorphism, Genetic; Proline; Selenium | 2009 |
AMINO ACID COMPOSITION OF HIGHLY PURIFIED VIRAL PARTICLES OF INFLUENZA A AND B.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Humans; Influenza, Human; Isoleucine; Leucine; Lysine; Methionine; Orthomyxoviridae; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine; Virion | 1947 |
Purification of Helicobacter pylori NCTC 11637 cytochrome bc1 and respiration with D-proline as a substrate.
Topics: Alanine; Bacterial Proteins; Cloning, Molecular; DNA, Bacterial; Electron Transport Complex III; Helicobacter pylori; Molecular Sequence Data; Molecular Weight; Oxidation-Reduction; Oxygen; Polarography; Proline; Sequence Analysis, DNA; Spectrophotometry | 2010 |
Interaction of maternal peroxisome proliferator-activated receptor gamma2 Pro12Ala polymorphism with fetal sex affects maternal glycemic control during pregnancy.
Topics: Adult; Alanine; Amino Acid Substitution; Blood Glucose; Female; Fetus; Genetic Predisposition to Disease; Humans; Male; Polymorphism, Single Nucleotide; PPAR gamma; Pregnancy; Proline; Sex Characteristics | 2010 |
Differential phospholipid binding of alpha-synuclein variants implicated in Parkinson's disease revealed by solution NMR spectroscopy.
Topics: Alanine; alpha-Synuclein; Genetic Variation; Glutamic Acid; Humans; Lysine; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Parkinson Disease; Peptide Fragments; Phospholipids; Proline; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Solutions; Threonine | 2010 |
Effects of interdomain tether length and flexibility on the kinetics of intramolecular electron transfer in human sulfite oxidase.
Topics: Alanine; Amino Acid Substitution; Animals; Catalytic Domain; Chickens; Conserved Sequence; Electron Spin Resonance Spectroscopy; Electron Transport; Humans; Kinetics; Molybdenum; Mutagenesis, Site-Directed; Peptides; Proline; Protein Structure, Tertiary; Recombinant Proteins; Sequence Deletion; Sulfite Oxidase | 2010 |
Helix propensities of conformationally restricted amino acids. Non-natural substitutes for helix breaking proline and helix forming alanine.
Topics: Alanine; Amino Acid Substitution; Models, Molecular; Proline; Protein Conformation; Protein Stability; Protein Structure, Secondary | 2010 |
Major differences in the proportion of amino acid fiber types transmitting taste information from oral and extraoral regions in the channel catfish.
Topics: Alanine; Amino Acids; Animals; Appetite; Arginine; Behavior, Animal; Catfishes; Facial Nerve; Glossopharyngeal Nerve; Models, Animal; Nerve Fibers; Proline; Sensitivity and Specificity; Stimulation, Chemical; Taste; Taste Buds | 2010 |
A novel mutation of 5alpha-steroid reductase 2 deficiency (CD 65 ALA-PRO) with severe virilization defect in a Turkish family and difficulty in gender assignment.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Alanine; Child; Codon; Exons; Family; Female; Gender Identity; Homozygote; Humans; Point Mutation; Proline; Sex Characteristics; Turkey | 2010 |
Poor outcome after liver transplantation for transthyretin amyloid neuropathy in a family with an Ala36Pro transthyretin mutation: case report.
Topics: Adult; Alanine; Amyloid Neuropathies, Familial; Family Health; Fatal Outcome; Female; Genotype; Humans; Liver Transplantation; Male; Mutation; Prealbumin; Proline; Treatment Outcome | 2010 |
First appraisal of brain pathology owing to A30P mutant alpha-synuclein.
Topics: Aged; Alanine; alpha-Synuclein; Brain; Brain Diseases; Family Health; Glial Fibrillary Acidic Protein; Humans; Inclusion Bodies; Male; Mutation; Proline | 2010 |
Peroxisome proliferator-activated receptor gamma polymorphism and periodontitis in pregnant Japanese women.
Topics: Alanine; Amino Acid Substitution; Chi-Square Distribution; Dental Plaque; DNA Mutational Analysis; Female; Humans; Japan; Mutation, Missense; Periodontitis; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; PPAR gamma; Pregnancy; Pregnancy Complications; Premature Birth; Proline; Statistics, Nonparametric | 2010 |
Efficient asymmetric organocatalytic formation of erythrose and threose under aqueous conditions.
Topics: Alanine; Catalysis; Leucine; Prebiotics; Proline; Stereoisomerism; Tetroses; Water | 2010 |
Taste genes associated with dental caries.
Topics: Adenine; Adult; Alanine; Child; Child, Preschool; Cohort Studies; Cytosine; Dental Caries; Dental Caries Susceptibility; DMF Index; Female; Gene Frequency; Genetic Variation; Genotype; Guanine; Haplotypes; Humans; Linkage Disequilibrium; Male; Polymorphism, Single Nucleotide; Proline; Receptors, G-Protein-Coupled; Risk Factors; Taste; Thymine; Transducin; Valine | 2010 |
Acquisition of Raman spectra of amino acids using portable instruments: outdoor measurements and comparison.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; beta-Alanine; Glutamic Acid; Glutamine; Glycine; Methionine; Proline; Research Design; Robotics; Serine; Spectrum Analysis, Raman; Transportation; Tryptophan; Tyrosine; Workplace | 2010 |
Identification of metastable states in peptide's dynamics.
Topics: Alanine; Leucine; Markov Chains; Molecular Dynamics Simulation; Oligopeptides; Proline; Protein Conformation; Valine | 2010 |
Manganese superoxide dismutase dimorphism relationship with severity and prognosis in cardiogenic shock due to dilated cardiomyopathy.
Topics: Alanine; Alleles; Biomarkers; Cardiomyopathy, Dilated; Cohort Studies; Female; Genetic Association Studies; Genotype; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Leucine; Male; Middle Aged; Natriuretic Peptide, Brain; Oxidative Stress; Polymorphism, Genetic; Prognosis; Proline; Reactive Oxygen Species; Severity of Illness Index; Shock, Cardiogenic; Superoxide Dismutase; Valine | 2011 |
Gender differences in the effects of peroxisome proliferator-activated receptor γ2 gene polymorphisms on metabolic adversity in patients with schizophrenia or schizoaffective disorder.
Topics: Adult; Alanine; Female; Gene Frequency; Genotype; Humans; Male; Metabolic Diseases; Metabolic Syndrome; Middle Aged; Obesity; Polymorphism, Genetic; PPAR gamma; Proline; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Sex Characteristics | 2011 |
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 in patients with fatty liver diseases.
Topics: Alanine; Biopsy; Fatty Liver; Humans; Polymorphism, Genetic; PPAR gamma; Proline | 2010 |
[Association of PPARgamma2 Pro12Ala polymorphism and cognitive dysfunction in hypertension patients].
Topics: Aged; Alanine; Alleles; Cognition Disorders; Female; Gene Frequency; Humans; Hypertension; Male; Middle Aged; Polymorphism, Genetic; PPAR gamma; Proline | 2010 |
Application of L-proline derivatives as chiral shift reagents for enantiomeric recognition of carboxylic acids.
Topics: Alanine; Amino Acids; Carboxylic Acids; Indicators and Reagents; Least-Squares Analysis; Magnetic Resonance Spectroscopy; Molecular Structure; Nonlinear Dynamics; Proline; Stereoisomerism | 2011 |
PPAR-gamma2 pro12Ala polymorphism is associated with post-challenge abnormalities of glucose homeostasis in children and adolescents with obesity.
Topics: Adolescent; Alanine; Amino Acid Substitution; Child; Cohort Studies; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Glucose; Glucose Metabolism Disorders; Glucose Tolerance Test; Homeostasis; Humans; Male; Obesity; Polymorphism, Single Nucleotide; PPAR gamma; Proline | 2011 |
Sequence analysis of PAX9, MSX1 and AXIN2 genes in a Chinese oligodontia family.
Topics: Alanine; Anodontia; Axin Protein; China; Cuspid; Exons; Female; Humans; Incisor; Male; Molar, Third; MSX1 Transcription Factor; Mutation; PAX9 Transcription Factor; Phenotype; Polymorphism, Genetic; Proline; Radiography, Panoramic; Retrospective Studies; Sequence Analysis, DNA; Tooth Crown; Tooth Germ | 2011 |
Discovery of potent hepatitis C virus NS5A inhibitors with dimeric structures.
Topics: Alanine; Antiviral Agents; Carbamates; Cell Line; Chromatography, High Pressure Liquid; Diarrhea Viruses, Bovine Viral; Drug Discovery; Drug Resistance, Viral; Hepacivirus; Humans; Imidazoles; Mass Spectrometry; Nuclear Magnetic Resonance, Biomolecular; Proline; Pyrrolidines; Stilbenes; Thiazolidines; Valine; Viral Nonstructural Proteins; Virus Replication | 2011 |
Pro12Ala polymorphism in human peroxisome proliferator activated receptor gamma is associated with hyperlipidaemia in obstructive sleep apnoea hypopnoea syndrome.
Topics: Adult; Alanine; Amino Acid Substitution; Body Mass Index; Case-Control Studies; China; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Hyperlipidemias; Linear Models; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; PPAR gamma; Proline; Severity of Illness Index; Sleep Apnea, Obstructive | 2011 |
Dopamine-depletion and increased α-synuclein load induce degeneration of cortical cholinergic fibers in mice.
Topics: Acetylcholinesterase; Alanine; alpha-Synuclein; Analysis of Variance; Animals; bcl-2-Associated X Protein; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Choline O-Acetyltransferase; Cholinergic Fibers; Disease Models, Animal; Dopamine; Gene Expression Regulation; Mice; Mice, Inbred C57BL; Mice, Transgenic; MPTP Poisoning; Mutation; Neurons; Proline; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptor, trkB; Time Factors | 2011 |
Solid-phase synthesis of smac peptidomimetics incorporating triazoloprolines and biarylalanines.
Topics: Alanine; Alkynes; Azides; Catalysis; Copper; Hydrocarbons, Aromatic; Inhibitor of Apoptosis Proteins; Models, Chemical; Oligopeptides; Palladium; Peptidomimetics; Proline; Solid-Phase Synthesis Techniques; Triazoles | 2011 |
Fragmentation reactions of b(5) and a (5) ions containing proline--the structures of a(5) ions.
Topics: Alanine; Ions; Oligopeptides; Peptides; Proline; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2012 |
Caveolin-1 hydrophobic segment peptides insertion into membrane mimetic systems: role of proline residue.
Topics: Alanine; Amino Acid Sequence; Biomimetics; Caveolae; Caveolin 1; Cholesterol; Circular Dichroism; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Liposomes; Molecular Sequence Data; Peptides; Proline; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence | 2012 |
Association of serum uric acid with Pro12Ala polymorphism in PPAR-γ2 among Chinese nonagenarians/centenarians.
Topics: Age Factors; Aged; Aged, 80 and over; Alanine; Asian People; Female; Genotype; Humans; Hyperuricemia; Male; Polymorphism, Genetic; PPAR gamma; Prevalence; Proline; Uric Acid | 2012 |
Association of serum lipid/lipoprotein with Pro12Ala polymorphism in PPAR-γ2 among Chinese nonagenarians/centenarians.
Topics: Aged; Aged, 80 and over; Alanine; Base Sequence; China; DNA Primers; Female; Humans; Lipids; Lipoproteins; Male; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; PPAR gamma; Proline | 2011 |
Combining flagelliform and dragline spider silk motifs to produce tunable synthetic biopolymer fibers.
Topics: Alanine; Amino Acid Motifs; Animals; Biomechanical Phenomena; Biopolymers; Elasticity; Fibroins; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Molecular Weight; Proline; Protein Structure, Secondary; Recombinant Fusion Proteins; Solutions; Spiders; Tensile Strength; Water; X-Ray Diffraction | 2012 |
Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline.
Topics: Alanine; Alcohols; Amino Acid Sequence; Gamma Rays; Glycine; Hydrogen Peroxide; Hydroxyl Radical; Molecular Weight; Oxidation-Reduction; Oxygen; Peptides; Proline; Protein Carbonylation; Proteolysis; Tandem Mass Spectrometry; Valine | 2012 |
Effect of P to A mutation of the N-terminal residue adjacent to the Rgd motif on rhodostomin: importance of dynamics in integrin recognition.
Topics: Alanine; Amino Acid Substitution; Animals; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Humans; Integrin alpha5beta1; Integrins; K562 Cells; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Peptides; Point Mutation; Proline; Protein Binding; Protein Interaction Domains and Motifs; Snakes | 2012 |
[Determination of amino acid contents in cottonseeds using near infrared reflectance spectroscopy].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Calibration; Cottonseed Oil; Cystine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Spectroscopy, Near-Infrared; Threonine; Tyrosine; Valine | 2011 |
Solubility and solution stability studies of different amino acid prodrugs of bromhexine.
Topics: Alanine; Bromhexine; Drug Stability; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Prodrugs; Proline; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared | 2012 |
Gly or Ala substitutions for Pro(210)Thr(211)Asn(212) at the β8-β9 turn of subtilisin Carlsberg increase the catalytic rate and decrease thermostability.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Bacillus; Bacterial Proteins; Biocatalysis; Catalytic Domain; Enzyme Stability; Glycine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Proline; Proteolysis; Sequence Homology, Amino Acid; Subtilisins; Threonine | 2012 |
Pro12Ala polymorphism of the PPAR-γ2 gene, metabolic syndrome and response to metformin in clozapine-treated patients.
Topics: Adult; Aged; Alanine; Antipsychotic Agents; Blood Glucose; Clozapine; Enzyme-Linked Immunosorbent Assay; Female; Gene Frequency; Genotype; Humans; Hypoglycemic Agents; Insulin; Leptin; Male; Metabolic Diseases; Metformin; Middle Aged; Polymorphism, Genetic; PPAR gamma; Proline | 2012 |
Effect of amino acids on red pigments and citrinin production in Monascus ruber.
Topics: Alanine; Amino Acids; Citrinin; Culture Media; Fermentation; Glutamic Acid; Histidine; Monascus; Nitrogen; Pigments, Biological; Proline | 2012 |
Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident coronary heart disease in a Hong Kong Chinese population.
Topics: Adult; Alanine; Amino Acid Substitution; Asian People; Case-Control Studies; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Female; Genetic Association Studies; Hong Kong; Humans; Incidence; Male; Middle Aged; Polymorphism, Single Nucleotide; PPAR gamma; Proline | 2012 |
Prenylation at the indole ring leads to a significant increase of cytotoxicity of tryptophan-containing cyclic dipeptides.
Topics: Alanine; Biocatalysis; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Dimethylallyltranstransferase; Dipeptides; Fungal Proteins; Hemiterpenes; Humans; Indoles; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Organophosphorus Compounds; Peptides, Cyclic; Prenylation; Proline; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity; Tryptophan | 2012 |
Understanding the drug resistance mechanism of hepatitis C virus NS3/4A to ITMN-191 due to R155K, A156V, D168A/E mutations: a computational study.
Topics: Alanine; Amino Acid Substitution; Antiviral Agents; Arginine; Aspartic Acid; Comprehension; Computational Biology; Cyclopropanes; Drug Resistance, Viral; Glutamic Acid; Hepacivirus; Isoindoles; Lactams; Lactams, Macrocyclic; Lysine; Models, Molecular; Molecular Dynamics Simulation; Mutation, Missense; Proline; Sulfonamides; Valine; Viral Nonstructural Proteins | 2012 |
A versatile proline/alanine transporter in the unicellular pathogen Leishmania donovani regulates amino acid homoeostasis and osmotic stress responses.
Topics: Adaptation, Physiological; Alanine; Amino Acid Transport Systems, Neutral; Amino Acids; Arginine; Biological Transport; Blotting, Northern; Blotting, Western; Cell Membrane; Gene Expression; Genetic Complementation Test; Glutamic Acid; Homeostasis; Leishmania donovani; Microscopy, Fluorescence; Mutation; Osmotic Pressure; Proline; Protozoan Proteins; Saccharomyces cerevisiae; Stress, Physiological | 2013 |
PPARγ2 Pro12Ala polymorphism is associated with improved lipoprotein lipase functioning in adipose tissue of insulin resistant obese women.
Topics: Adipose Tissue; Adult; Alanine; Base Sequence; DNA Primers; Female; Humans; Insulin Resistance; Lipoprotein Lipase; Middle Aged; Obesity; Polymerase Chain Reaction; PPAR gamma; Proline | 2012 |
Risk for myasthenia gravis maps to a (151) Pro→Ala change in TNIP1 and to human leukocyte antigen-B*08.
Topics: Adult; Age of Onset; Alanine; Case-Control Studies; DNA-Binding Proteins; Europe; Female; Gene Frequency; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; HLA-B8 Antigen; Humans; Male; Meta-Analysis as Topic; Myasthenia Gravis; Polymorphism, Single Nucleotide; Proline; White People; Young Adult | 2012 |
2H-13C HETCOR MAS NMR for indirect detection of 2H quadrupole patterns and spin-lattice relaxation rates.
Topics: Alanine; Algorithms; Deuterium; Electromagnetic Fields; Isotope Labeling; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Proline | 2013 |
Oxidative stress parameters and anti-apoptotic response to hydroxyl radicals in fish erythrocytes: protective effects of glutamine, alanine, citrulline and proline.
Topics: Alanine; Animals; Apoptosis; Citrulline; Erythrocytes; Glutamine; Hydroxyl Radical; Oxidative Stress; Proline; Water Pollutants, Chemical | 2013 |
Immunogenicity and cross protective ability of the central VP2 amino acids of infectious pancreatic necrosis virus in Atlantic salmon (Salmo salar L.).
Topics: Alanine; Amino Acids; Animals; Antibodies, Viral; Antigens, Viral; Cross Reactions; Fish Diseases; Host-Pathogen Interactions; Immunohistochemistry; Infectious pancreatic necrosis virus; Pancreas, Exocrine; Proline; Salmo salar; Survival Analysis; Survival Rate; Threonine; Time Factors; Vaccination; Vaccines, Attenuated; Vaccines, Inactivated; Viral Structural Proteins; Viral Vaccines | 2013 |
Structures and free energy landscapes of the wild-type and A30P mutant-type α-synuclein proteins with dynamics.
Topics: Alanine; alpha-Synuclein; Energy Metabolism; Humans; Molecular Dynamics Simulation; Mutant Proteins; Mutation, Missense; Proline; Protein Structure, Secondary; Protein Structure, Tertiary | 2013 |
Crystallographic structure determination of B10 mutants of Vitreoscilla hemoglobin: role of Tyr29 (B10) in the structure of the ligand-binding site.
Topics: Alanine; Bacterial Proteins; Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Escherichia coli; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Oxygen; Phenylalanine; Proline; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Truncated Hemoglobins; Tyrosine; Vitreoscilla | 2013 |
A readily applicable strategy to convert peptides to peptoid-based therapeutics.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Peptides; Peptoids; Proline; Sarcosine | 2013 |
D-amino acid aberrations in cerebrospinal fluid and plasma of smokers.
Topics: Adult; Alanine; Alcohol Drinking; Excitatory Amino Acid Agonists; Female; Glycine; Humans; Male; Proline; Self Report; Serine; Smoking; Stereoisomerism | 2013 |
A Pro 12 Ala substitution in the PPARγ2 polymorphism may decrease the number of diseased vessels and the severity of angiographic coronary artery.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Amino Acid Substitution; Biomarkers; Blood Glucose; Case-Control Studies; Chi-Square Distribution; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Odds Ratio; Phenotype; Polymorphism, Genetic; PPAR gamma; Predictive Value of Tests; Proline; Risk Factors; Severity of Illness Index | 2013 |
Deracemization of amino acids by partial sublimation and via homochiral self-organization.
Topics: Alanine; Amino Acids; Leucine; Proline; Stereoisomerism; Valine | 2013 |
Flight muscle-specific Pro-Ala-rich extension of troponin is important for maintaining the insect-type myofilament lattice integrity.
Topics: Alanine; Animals; Bees; Flight, Animal; Fourier Analysis; Microscopy, Electron; Myofibrils; Proline; X-Ray Diffraction | 2013 |
Analysis of manganese superoxide dismutase (MnSOD: Ala-9Val) and glutathione peroxidase (GSH-Px: Pro 197 Leu) gene polymorphisms in mood disorders.
Topics: Adult; Alanine; Alleles; Bipolar Disorder; Case-Control Studies; Depressive Disorder, Major; Female; Genotype; Glutathione Peroxidase; Humans; Leucine; Male; Middle Aged; Polymorphism, Genetic; Proline; Real-Time Polymerase Chain Reaction; Superoxide Dismutase; Valine | 2013 |
ADAMTS13 predicts renal and cardiovascular events in type 2 diabetic patients and response to therapy.
Topics: ADAM Proteins; ADAMTS13 Protein; Aged; Alanine; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Disease Progression; Female; Genotype; Humans; Kidney Failure, Chronic; Male; Middle Aged; Polymorphism, Single Nucleotide; Predictive Value of Tests; Proline; Proteolysis; Risk Assessment; Risk Factors; von Willebrand Factor | 2013 |
PASylation: a biological alternative to PEGylation for extending the plasma half-life of pharmaceutically active proteins.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Escherichia coli; Growth Hormone; Half-Life; Humans; Immunoglobulin Fab Fragments; Mice; Models, Molecular; Molecular Sequence Data; Peptides; Polyethylene Glycols; Proline; Protein Structure, Secondary; Recombinant Fusion Proteins; Serine | 2013 |
Consequences of proline-to-alanine substitutions for the stability and refolding of onconase.
Topics: Alanine; Amino Acid Substitution; Amphibian Proteins; Animals; Biocatalysis; Escherichia coli; Kinetics; Models, Molecular; Proline; Protein Refolding; Protein Stability; Protein Structure, Tertiary; Rana pipiens; Recombinant Proteins; Ribonucleases; Thermodynamics | 2013 |
Glial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice.
Topics: Alanine; alpha-Synuclein; Animals; Anxiety; Avoidance Learning; Cell Count; Disease Models, Animal; Doublecortin Domain Proteins; Doxycycline; Gene Expression Regulation; Hippocampus; Humans; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurogenesis; Neuroglia; Neuropeptides; Olfactory Bulb; Proline | 2013 |
The association between the Pro12Ala variant in the PPARγ2 gene and type 2 diabetes mellitus and obesity in a Chinese population.
Topics: Adult; Alanine; Amino Acid Substitution; Asian People; Blood Glucose; Body Mass Index; China; Diabetes Mellitus, Type 2; Fasting; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Insulin; Male; Middle Aged; Obesity; Odds Ratio; Polymorphism, Genetic; PPAR gamma; Proline | 2013 |
An alanine-to-proline mutation in the BB-loop of TLR3 Toll/IL-1R domain switches signalling adaptor specificity from TRIF to MyD88.
Topics: Adaptor Proteins, Vesicular Transport; Alanine; Amino Acid Substitution; Binding Sites; HEK293 Cells; Humans; Interferon Regulatory Factor-3; Mutation, Missense; Myeloid Differentiation Factor 88; NF-kappa B; Point Mutation; Poly I-C; Proline; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Signal Transduction; Species Specificity; Structure-Activity Relationship; TNF Receptor-Associated Factor 6; Toll-Like Receptor 3 | 2013 |
Molecular characterization of an alanine-, proline-, glycine-, threonine-, and serine-rich protein of the hard tick Haemaphysalis qinghaiensis and its effect as a vaccine against tick infestation in sheep.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; DNA, Complementary; Glycine; Immunity, Active; Ixodidae; Molecular Sequence Data; Phylogeny; Proline; Rabbits; Recombinant Proteins; Sequence Analysis, DNA; Serine; Sheep; Sheep Diseases; Threonine; Tick Infestations; Vaccination; Vaccines | 2014 |
An in vitro based investigation into the cytotoxic effects of D-amino acids.
Topics: Alanine; Amino Acids; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; HeLa Cells; Humans; Hydrogen Peroxide; Lysine; MCF-7 Cells; Proline; Stereoisomerism | 2013 |
Dietary L-lysine prevents arterial calcification in adenine-induced uremic rats.
Topics: Adenine; Alanine; Animals; Apoptosis; Arginine; Calcium; Calcium Phosphates; Cells, Cultured; Chemical Precipitation; Creatinine; Dietary Supplements; Homoarginine; Humans; Lysine; Male; Metabolic Networks and Pathways; Myocytes, Smooth Muscle; Osteoporosis; Proline; Rats; Rats, Sprague-Dawley; Solutions; Uremia; Vascular Calcification | 2014 |
Biochemical and radical-scavenging properties of sea cucumber (Stichopus vastus) collagen hydrolysates.
Topics: Alanine; Amino Acids; Animals; Antioxidants; Collagen; Electrophoresis, Polyacrylamide Gel; Free Radical Scavengers; Glutamic Acid; Glycine; Hydrolysis; Hydroxyproline; Molecular Structure; Molecular Weight; Proline; Protein Hydrolysates; Stichopus | 2014 |
The beneficial effect of a prolyl oligopeptidase inhibitor, KYP-2047, on alpha-synuclein clearance and autophagy in A30P transgenic mouse.
Topics: Alanine; alpha-Synuclein; Animals; Autophagy; Brain; Brain Diseases; Cell Line, Transformed; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Mutation; Proline; Prolyl Oligopeptidases; Serine Endopeptidases; Serine Proteinase Inhibitors; Time Factors | 2014 |
Peroxisome proliferator activated receptor γ2 gene Pro12Ala gene polymorphism in type 2 diabetes and its relationship with diabetic nephropathy.
Topics: Aged; Aged, 80 and over; Alanine; Amino Acid Substitution; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Genotype; Humans; Male; Middle Aged; Polymorphism, Genetic; PPAR gamma; Proline | 2014 |
Combined supplementation of carbohydrate, alanine, and proline is effective in maintaining blood glucose and increasing endurance performance during long-term exercise in mice.
Topics: Administration, Oral; Alanine; Animals; Blood Glucose; Dietary Carbohydrates; Dietary Supplements; Glucagon; Glycogen; Liver; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Physical Conditioning, Animal; Physical Endurance; Polysaccharides; Proline | 2014 |
[The influence of low partial oxygen pressure on the biolodical process of mesenchymal stromal cells].
Topics: Alanine; Aspartic Acid; Cell Hypoxia; Cell Line; Collagen; Culture Media; Glutamine; Humans; Hydroxyproline; Mesenchymal Stem Cells; Oxygen; Proline; Serine | 2014 |
Host diapause status and host diets augmented with cryoprotectants enhance cold hardiness in the parasitoid Nasonia vitripennis.
Topics: Alanine; Animals; Cold Temperature; Cryoprotective Agents; Diapause, Insect; Diet; Glycerol; Larva; Proline; Pupa; Sarcophagidae; Wasps | 2014 |
PPARγ2 Pro12Ala polymorphism was associated with favorable cardiometabolic risk profile in HIV/HCV coinfected patients: a cross-sectional study.
Topics: Adult; Alanine; Amino Acid Substitution; Cardiovascular Diseases; Coinfection; Cross-Sectional Studies; Female; Genetic Predisposition to Disease; Hepatitis C; HIV Infections; HIV-1; Humans; Male; Metabolic Diseases; Metabolome; Middle Aged; Polymorphism, Single Nucleotide; PPAR gamma; Proline; Risk Factors | 2014 |
Computational and experimental investigation of constitutive behavior in AraC.
Topics: Alanine; Allosteric Regulation; Amino Acid Substitution; Arabinose; AraC Transcription Factor; Biocatalysis; Catalytic Domain; Databases, Protein; Dimerization; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Glycine; Models, Molecular; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Mutation; Operon; Proline; Protein Conformation; Protein Interaction Domains and Motifs | 2014 |
Alanine and proline content modulate global sensitivity to discrete perturbations in disordered proteins.
Topics: Alanine; Amino Acid Substitution; Circular Dichroism; Humans; Hydrodynamics; Hydrophobic and Hydrophilic Interactions; Intrinsically Disordered Proteins; Models, Molecular; Mutation; Nephelometry and Turbidimetry; Peptide Fragments; Proline; Protein Conformation; Protein Folding; Protein Interaction Domains and Motifs; Protein Stability; Recombinant Proteins; Tumor Suppressor Protein p53 | 2014 |
In vivo regulation of intestinal absorption of amino acids by leptin.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Glutamine; Intestinal Absorption; Intestinal Mucosa; Intestines; Leptin; Male; Proline; Rats; Rats, Wistar; Time Factors | 2015 |
A cancer-associated mutation inactivates a region of the high-mobility group protein HMG20b essential for cytokinesis.
Topics: Alanine; BRCA2 Protein; Cytokinesis; DNA-Binding Proteins; HeLa Cells; High Mobility Group Proteins; Humans; Lung Neoplasms; Mutation; Proline | 2014 |
Variation in PPARG is associated with longitudinal change in insulin resistance in Mexican Americans at risk for type 2 diabetes.
Topics: Adult; Alanine; Amino Acid Substitution; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Humans; Insulin Resistance; Longitudinal Studies; Male; Mexican Americans; Polymorphism, Single Nucleotide; PPAR gamma; Proline; Young Adult | 2015 |
Safety of long-term dietary supplementation with L-arginine in pigs.
Topics: Adipose Tissue, White; Alanine; Ammonia; Animals; Animals, Suckling; Arginine; Body Composition; Cholesterol; Dietary Supplements; Female; Glutamine; Glycine; Male; Muscle, Skeletal; Ornithine; Proline; Swine; Time Factors; Triglycerides; Weaning | 2015 |
Genome-wide association study of NMDA receptor coagonists in human cerebrospinal fluid and plasma.
Topics: Adolescent; Adult; Alanine; Chromatography, Liquid; Female; Genetic Variation; Genome-Wide Association Study; Glycine; Humans; Male; Membrane Transport Proteins; Middle Aged; Proline; Proline Oxidase; Quantitative Trait Loci; Receptors, N-Methyl-D-Aspartate; Serine; Tandem Mass Spectrometry; Young Adult | 2015 |
Role of Conserved Proline Residues in Human Apolipoprotein A-IV Structure and Function.
Topics: Alanine; Amino Acid Substitution; Apolipoproteins A; Cholesterol; Conserved Sequence; Humans; Liposomes; Models, Molecular; Mutagenesis, Site-Directed; Proline; Protein Binding; Protein Multimerization; Protein Stability; Protein Structure, Quaternary; Protein Structure, Secondary; Recombinant Proteins; Scattering, Small Angle; Thermodynamics; X-Ray Diffraction | 2015 |
Structural studies of the C-terminal 19-peptide of serum amyloid A and its Pro → Ala variants interacting with human cystatin C.
Topics: Alanine; Calorimetry, Differential Scanning; Chromatography, Affinity; Circular Dichroism; Cystatin C; Humans; Peptides; Proline; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Serum Amyloid A Protein | 2015 |
The Interaction Between β-3 Adrenergic Receptor and Peroxisome Proliferator-Activated Receptor Gamma Gene Polymorphism to Periodontal Disease in Community-Dwelling Elderly Japanese.
Topics: Aged; Alanine; Arginine; Body Mass Index; C-Reactive Protein; Epistasis, Genetic; Female; Gene-Environment Interaction; Genotype; Glycated Hemoglobin; Heterozygote; Humans; Middle Aged; Obesity; Periodontal Attachment Loss; Periodontal Diseases; Periodontal Index; Periodontal Pocket; Polymorphism, Genetic; Postmenopause; PPAR gamma; Proline; Receptors, Adrenergic, beta-3; Tooth Loss; Tryptophan | 2015 |
Probing the role of Proline in the antimicrobial activity and lipopolysaccharide binding of indolicidin.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Binding Sites; Cattle; Escherichia coli; Klebsiella pneumoniae; Lipopolysaccharides; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Neutrophils; Proline; Protein Binding; Protein Conformation; Pseudomonas aeruginosa; Salmonella typhi; Structure-Activity Relationship; Tryptophan | 2015 |
Role of host cell-derived amino acids in nutrition of intracellular Salmonella enterica.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Bacterial Proteins; Gene Expression Regulation, Bacterial; Glutamine; Glycoproteins; HeLa Cells; Host-Pathogen Interactions; Humans; Mice; Proline; Salmonella enterica; Succinate Dehydrogenase; Succinic Acid; Vacuoles | 2015 |
Role of amino acids as additives on sperm motility, plasma membrane integrity and lipid peroxidation levels at pre-freeze and post-thawed ram semen.
Topics: Alanine; Amino Acids; Animals; Cell Membrane; Cryopreservation; Glutamine; Lipid Peroxidation; Male; Proline; Semen; Sheep; Sperm Motility; Spermatozoa | 2015 |
Normal cardiac contraction in mice lacking the proline-alanine rich region and C1 domain of cardiac myosin binding protein C.
Topics: Adrenergic beta-Agonists; Alanine; Amino Acid Sequence; Animals; Calcium; Carrier Proteins; Echocardiography; Gene Expression; Humans; Isoproterenol; Mice; Mice, Knockout; Molecular Sequence Data; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Proline; Protein Structure, Tertiary; Sarcomeres; Sequence Deletion; Stroke Volume; Systole | 2015 |
Intracellular Activation of Tenofovir Alafenamide and the Effect of Viral and Host Protease Inhibitors.
Topics: Adenine; Alanine; Anti-HIV Agents; Biotransformation; Carboxylic Ester Hydrolases; Cathepsin A; CD4-Positive T-Lymphocytes; Cobicistat; Drug Interactions; Gene Expression; HEK293 Cells; HeLa Cells; HIV-1; Host-Pathogen Interactions; Humans; Oligopeptides; Primary Cell Culture; Prodrugs; Proline; RNA, Small Interfering; Serine Proteinase Inhibitors; Tenofovir | 2016 |
Size does matter: 18 amino acids at the N-terminal tip of an amino acid transporter in Leishmania determine substrate specificity.
Topics: Alanine; Alternative Splicing; Amino Acid Sequence; Amino Acid Transport Systems; Humans; Leishmania; Leishmaniasis; Proline; Substrate Specificity | 2015 |
Quantitative determination of carboxylic acids, amino acids, carbohydrates, ethanol and hydroxymethylfurfural in honey by (1)H NMR.
Topics: Alanine; Amino Acids; Carbohydrates; Carboxylic Acids; Ethanol; Flowers; Fructose; Furaldehyde; Glucose; Hexoses; Honey; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Proline; Regression Analysis; Thymus Plant | 2016 |
Improved Doxorubicin Encapsulation and Pharmacokinetics of Ferritin-Fusion Protein Nanocarriers Bearing Proline, Serine, and Alanine Elements.
Topics: Alanine; Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Screening Assays, Antitumor; Drug Stability; Ferritins; Half-Life; Humans; Mice, Inbred BALB C; Nanocapsules; Peptides; Polyethylene Glycols; Proline; Recombinant Fusion Proteins; Serine | 2016 |
Revealing Potential Biomarkers of Functional Dyspepsia by Combining 1H NMR Metabonomics Techniques and an Integrative Multi-objective Optimization Method.
Topics: Adult; Alanine; Algorithms; Biomarkers; Blood Glucose; Case-Control Studies; Dyspepsia; Female; Glutamine; Humans; Lipoproteins, HDL; Magnetic Resonance Spectroscopy; Metabolic Networks and Pathways; Metabolome; Prognosis; Proline; Severity of Illness Index | 2016 |
Reconstitution and spectroscopic analysis of caveolin-1 residues 62-178 reveals that proline 110 governs its structure and solvent exposure.
Topics: Alanine; Caveolin 1; Cholesterol; Circular Dichroism; Hydrophobic and Hydrophilic Interactions; Micelles; Mutation; Phosphorylcholine; Proline; Protein Structure, Secondary; Solvents; Structure-Activity Relationship; Tryptophan | 2016 |
The A31P missense mutation in cardiac myosin binding protein C alters protein structure but does not cause haploinsufficiency.
Topics: Alanine; Animals; Cardiomyopathy, Hypertrophic; Carrier Proteins; Cats; Circular Dichroism; Codon, Terminator; Haploinsufficiency; Heart; Immunohistochemistry; Muscle Cells; Mutation; Mutation, Missense; Myocardium; Proline; Protein Conformation; Protein Domains; Protein Structure, Secondary; Recombinant Proteins; Sarcomeres | 2016 |
Asymmetric Synthesis of N-Boc-(R)-Silaproline via Rh-Catalyzed Intramolecular Hydrosilylation of Dehydroalanine and Continuous Flow N-Alkylation.
Topics: Alanine; Alkylation; Catalysis; Cyclization; Organosilicon Compounds; Proline | 2016 |
Profiling of plasma metabolites in postmenopausal women with metabolic syndrome.
Topics: 2-Aminoadipate Transaminase; Adult; Aged; Alanine; Amino Acids; Amino Acids, Branched-Chain; Asian People; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Fasting; Female; Glutamic Acid; Humans; Japan; Metabolic Syndrome; Metabolome; Middle Aged; Postmenopause; Proline | 2016 |
Earthworms accumulate alanine in response to drought.
Topics: Adaptation, Physiological; Alanine; Analysis of Variance; Animals; Droughts; Ecosystem; Estivation; Oligochaeta; Proline; Soil; Species Specificity | 2016 |
Association of Pro12Ala Polymorphism of Peroxisome Proliferator-Activated Receptor gamma 2 (PPARγ2) Gene with Type 2 Diabetes Mellitus in Ethnic Kashmiri Population.
Topics: Adult; Alanine; Asian People; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Genotype; Humans; India; Male; Polymorphism, Genetic; PPAR gamma; Proline | 2017 |
Metabolic profiling of root exudates from two ecotypes of Sedum alfredii treated with Pb based on GC-MS.
Topics: Alanine; Biomarkers; Ecotype; Gas Chromatography-Mass Spectrometry; Lead; Metabolome; Oxalic Acid; Plant Roots; Principal Component Analysis; Proline; Sedum; Soil Pollutants | 2017 |
Structural role of a conserved active site cis proline in the Thermotoga maritima acetyl esterase from the carbohydrate esterase family 7.
Topics: Acetylesterase; Alanine; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Biocatalysis; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Gene Expression; Kinetics; Models, Molecular; Mutation; Proline; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Thermotoga maritima | 2017 |
The substitution of Proline 168 favors Bax oligomerization and stimulates its interaction with LUVs and mitochondria.
Topics: Alanine; Amino Acid Substitution; bcl-2-Associated X Protein; Cloning, Molecular; Cytochromes c; Gene Expression; HCT116 Cells; Humans; Liposomes; Mitochondria; Mutation; Permeability; Proline; Protein Binding; Protein Multimerization; Protein Structure, Secondary; Recombinant Proteins; Saccharomyces cerevisiae; Unilamellar Liposomes | 2017 |
N-terminal diproline and charge group effects on the stabilization of helical conformation in alanine-based short peptides: CD studies with water and methanol as solvent.
Topics: Alanine; Circular Dichroism; Methanol; Peptides; Proline; Protein Conformation; Protein Stability; Solvents; Water | 2017 |
Quality control by trans-editing factor prevents global mistranslation of non-protein amino acid α-aminobutyrate.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Aminobutyrates; Anticodon; Binding Sites; Codon; Escherichia coli; Kinetics; Molecular Docking Simulation; Mutation; Nucleic Acid Conformation; Proline; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Rhodopseudomonas; RNA Processing, Post-Transcriptional; RNA, Transfer, Pro; Substrate Specificity; Transfer RNA Aminoacylation | 2018 |
Na+/H+ Exchanger Regulates Amino Acid-Mediated Autophagy in Intestinal Epithelial Cells.
Topics: Alanine; Amiloride; Amino Acids; Animals; Autophagy; Autophagy-Related Proteins; Cell Line; Epithelial Cells; Intestinal Mucosa; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Microtubule-Associated Proteins; Proline; Rats; Real-Time Polymerase Chain Reaction; Sodium-Hydrogen Exchangers; Up-Regulation | 2017 |
Visualizing tRNA-dependent mistranslation in human cells.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Aminoacylation; Anticodon; Cell Survival; Codon; Culture Media; Escherichia coli; Genes, Reporter; Glucose; Green Fluorescent Proteins; HEK293 Cells; Humans; Mutation; Plasmids; Proline; Proteasome Endopeptidase Complex; Protein Biosynthesis; RNA Processing, Post-Transcriptional; RNA, Transfer, Pro; Transfection | 2018 |
Prospects of PASylation® for the design of protein and peptide therapeutics with extended half-life and enhanced action.
Topics: Alanine; Animals; Drug Discovery; Half-Life; Humans; Models, Molecular; Peptides; Polyethylene Glycols; Proline; Serine | 2018 |
Incomplete Refolding of Antibody Light Chains to Non-Native, Protease-Sensitive Conformations Leads to Aggregation: A Mechanism of Amyloidogenesis in Patients?
Topics: Alanine; Amyloid; Amyloidosis; Circular Dichroism; Endopeptidases; Humans; Immunoglobulin Light Chains; Kinetics; Models, Molecular; Proline; Protein Aggregates; Protein Conformation; Protein Folding; Thermodynamics | 2017 |
Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid.
Topics: Alanine; Alanine-tRNA Ligase; Amino Acids; Amino Acyl-tRNA Synthetases; Azetidinecarboxylic Acid; Cell Death; HeLa Cells; Humans; Molecular Mimicry; Proline; Protein Biosynthesis; RNA Editing; RNA, Transfer; Vegetables | 2017 |
Low levels of serum serotonin and amino acids identified in migraine patients.
Topics: Adult; Alanine; Arginine; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Dipeptides; Discriminant Analysis; Female; Humans; Male; Metabolome; Methionine; Migraine Disorders; Principal Component Analysis; Proline; RNA, Transfer, Amino Acyl; ROC Curve; Serotonin; Tryptophan | 2018 |
The role of Ala134 in controlling substrate binding and reactivity in ascorbate peroxidase.
Topics: Alanine; Ascorbate Peroxidases; Ascorbic Acid; Catalysis; Chromatography, High Pressure Liquid; Guaiacol; Heme; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Oxidation-Reduction; Proline; Substrate Specificity | 2018 |
Can Mutational Analysis Be Used To Assist Structure Determination of Peptides?
Topics: Alanine; Bradykinin; Mutation; Proline; Protein Conformation | 2018 |
Understanding the antimicrobial properties/activity of an 11-residue Lys homopeptide by alanine and proline scan.
Topics: Alanine; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Bacteria; Polylysine; Proline | 2018 |
Stage-specific expression of the proline-alanine transporter in the human pathogen Leishmania.
Topics: Alanine; Amino Acid Transport Systems, Neutral; Animals; Humans; Insect Vectors; Leishmania donovani; Leishmaniasis, Visceral; Lysosomes; Phlebotomus; Proline; Proteasome Endopeptidase Complex; Proteolysis; Protozoan Proteins; Species Specificity | 2018 |
Development, Characterization, and In Vitro Testing of Co-Delivered Antimicrobial Dry Powder Formulation for the Treatment of Pseudomonas aeruginosa Biofilms.
Topics: Administration, Inhalation; Alanine; Anti-Bacterial Agents; Biofilms; Desiccation; Drug Compounding; Dry Powder Inhalers; Excipients; Humans; Particle Size; Powders; Proline; Pseudomonas aeruginosa; Pseudomonas Infections; Succinic Acid; Tobramycin | 2018 |
Effects of rearing system on meat quality, fatty acid and amino acid profiles of Hu lambs.
Topics: Alanine; Amino Acids; Animal Feed; Animal Husbandry; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Fatty Acids; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Food Quality; Leucine; Meat; Proline; Sheep; Time Factors; Weight Gain | 2018 |
The influence of chosen fungicides on the activity of aminopeptidases in winter oilseed rape during pods development.
Topics: Alanine; Amino Acids; Aminopeptidases; Brassica rapa; Crops, Agricultural; Fungicides, Industrial; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glycine; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Plant Structures; Proline; Seasons; Substrate Specificity | 2018 |
Quantum mechanical effects in zwitterionic amino acids: The case of proline, hydroxyproline, and alanine in water.
Topics: Alanine; Hydroxyproline; Molecular Dynamics Simulation; Proline; Quantum Theory; Water | 2018 |
Combined Supplementation of Pre-Exercise Carbohydrate, Alanine, and Proline and Continuous Intake of Green Tea Catechins Effectively Boost Endurance Performance in Mice.
Topics: Alanine; Animals; Calorimetry, Indirect; Camellia sinensis; Catechin; Dietary Carbohydrates; Dietary Supplements; Energy Metabolism; Food Handling; Lipid Metabolism; Male; Mice, Inbred BALB C; Oxidation-Reduction; Performance-Enhancing Substances; Physical Endurance; Plant Leaves; Polysaccharides; Proline; Psychomotor Performance; Running | 2018 |
Topics: Alanine; Aspartic Acid; Gene Expression Regulation; Histone Acetyltransferases; Histone-Lysine N-Methyltransferase; Humans; Metabolome; Metabolomics; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Proline; Protein Domains; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2019 |
Bioformation of Volatile and Nonvolatile Metabolites by
Topics: Acetates; Alanine; Carbon; Glutamic Acid; Glycine; Isoleucine; Mannitol; Mannose; Phenylacetates; Phenylalanine; Phenylethyl Alcohol; Proline; Saccharomycopsis; Serine; Sugar Alcohols; Threonine; Time Factors | 2018 |
Alanine, proline and urea are major organic osmolytes in the snail
Topics: Alanine; Animals; Fresh Water; Germany; Osmotic Pressure; Proline; Saline Waters; Salt Stress; Snails; Urea | 2019 |
Public health round-up.
Topics: Adenosine Monophosphate; Alanine; Aminoisobutyric Acids; Anti-Bacterial Agents; Antibodies, Monoclonal; Benzimidazoles; Cyclopropanes; Democratic Republic of the Congo; Disease Outbreaks; Drug Resistance, Bacterial; Global Health; Hemorrhagic Fever, Ebola; Hepatitis C; Humans; Interinstitutional Relations; Lactams, Macrocyclic; Leucine; Malaria; Measles; Measles Vaccine; Poliomyelitis; Proline; Public Health Practice; Pyrrolidines; Quinoxalines; Randomized Controlled Trials as Topic; Ribonucleotides; Sulfonamides; Tuberculosis | 2019 |
Exogenous γ-aminobutyric acid treatment improves the cold tolerance of zucchini fruit during postharvest storage.
Topics: 4-Aminobutyrate Transaminase; Adenosine Triphosphate; Alanine; Amine Oxidase (Copper-Containing); Cell Death; Cold Temperature; Cucurbita; Food Storage; Fruit; Fumarates; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Malates; NAD; Proline; Putrescine | 2019 |
THE ROLE OF PRO12ALA POLYMORPHISM OF THE PPAR-Γ GENE IN THE GENESIS OF THE GESTATIONAL WEIGHT GAIN.
Topics: Alanine; Blood Glucose; Cholesterol; Female; Genotype; Gestational Weight Gain; Humans; Insulin; Polymorphism, Single Nucleotide; PPAR gamma; Pregnancy; Proline; Triglycerides | 2018 |
Amino acids and proteomic acclimation of Staphylococcus aureus when incubated in a defined minimal medium supplemented with 5% sodium chloride.
Topics: Acclimatization; Alanine; Amino Acids; Aspartic Acid; Bacterial Proteins; Culture Media; Proline; Proteomics; Sodium Chloride; Staphylococcus aureus | 2019 |
Enhancing bioactivity, physicochemical, and pharmacokinetic properties of a nano-sized, anti-VEGFR2 Adnectin, through PASylation technology.
Topics: Alanine; Animals; Escherichia coli; Female; Fibronectins; Human Umbilical Vein Endothelial Cells; Humans; Kinetics; Mice; Mice, Inbred BALB C; Peptide Fragments; Proline; Protein Domains; Protein Engineering; Serine; Surface Plasmon Resonance; Vascular Endothelial Growth Factor Receptor-2 | 2019 |
Half-life extension and non-human primate pharmacokinetic safety studies of i-body AD-114 targeting human CXCR4.
Topics: Alanine; Animals; Bioengineering; Half-Life; Humans; Macaca fascicularis; Male; Mice; Mice, Inbred ICR; Pharmacokinetics; Polyethylene Glycols; Proline; Rats; Rats, Sprague-Dawley; Receptors, CXCR4; Single-Domain Antibodies | 2019 |
Description of a novel HLA-A allele, HLA-A*03:365, identified in a bone marrow donor from Russia.
Topics: Alanine; Alleles; Bone Marrow; Bone Marrow Transplantation; Exons; Female; HLA-A3 Antigen; Humans; Polymorphism, Single Nucleotide; Proline; Russia; Tissue Donors | 2019 |
Identification of plasmid encoded osmoregulatory genes from halophilic bacteria isolated from the rhizosphere of halophytes.
Topics: Alanine; Amino Acids, Diamino; Anti-Bacterial Agents; Atriplex; Bacteria; Bacterial Proteins; DNA, Bacterial; Gene Transfer, Horizontal; Osmoregulation; Oxidoreductases; Peptide Hydrolases; Phylogeny; Plasmids; Porins; Proline; Rhizosphere; Salt Tolerance; Salt-Tolerant Plants; Sodium Chloride; Soil; Soil Microbiology; Trehalose | 2019 |
Behavioural and dopaminergic changes in double mutated human A30P*A53T alpha-synuclein transgenic mouse model of Parkinson´s disease.
Topics: Aging; Alanine; alpha-Synuclein; Amino Acid Substitution; Animals; Behavior, Animal; Disease Models, Animal; Dopaminergic Neurons; Humans; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation, Missense; Parkinson Disease; Proline; Threonine | 2019 |
Metabolite Regulatory Interactions Control Plant Respiratory Metabolism via Target of Rapamycin (TOR) Kinase Activation.
Topics: Alanine; Arabidopsis; Arabidopsis Proteins; Cell Respiration; Enzyme Activation; Gene Expression Regulation, Plant; Metabolome; Models, Biological; Phosphatidylinositol 3-Kinases; Phosphoenolpyruvate; Plant Leaves; Proline; Pyruvate Dehydrogenase Complex; Time Factors | 2020 |
Pd-Catalyzed Asymmetric N-Allylation of Amino Acid Esters with Exceptional Levels of Catalyst Control: Stereo-Divergent Synthesis of ProM-15 and Related Bicyclic Dipeptide Mimetics.
Topics: Alanine; Amino Acids; Catalysis; Crystallography, X-Ray; Cycloaddition Reaction; Dipeptides; Esters; Ligands; Models, Molecular; Molecular Structure; Oxidation-Reduction; Palladium; Proline; Stereoisomerism | 2020 |
Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study.
Topics: Alanine; Amino Acids, Branched-Chain; Autoantibodies; Child, Preschool; Dehydroascorbic Acid; Diabetes Mellitus, Type 1; Fatty Acids; Female; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glutamate Decarboxylase; Humans; Infant; Infant, Newborn; Insulin Antibodies; Longitudinal Studies; Male; Metabolome; Methionine; Phosphatidylethanolamines; Prodromal Symptoms; Proline; Risk; Triglycerides | 2020 |
Topics: Adult; Aged; Alanine; Cardiovascular Diseases; Diet, Healthy; Female; Food Preferences; Genotype; Haplotypes; Humans; Independent Living; Male; Middle Aged; Proline; Risk Factors; Taste Perception; Valine; Vegetables | 2020 |
Alanine, arginine, cysteine, and proline, but not glutamine, are substrates for, and acute mediators of, the liver-α-cell axis in female mice.
Topics: Alanine; Amino Acids; Animals; Arginine; Blood Glucose; Cysteine; Female; Glucagon; Glucagon-Secreting Cells; Glutamine; In Vitro Techniques; Insulin; Liver; Mice; Proline; Receptors, Glucagon | 2020 |
Proline/alanine-rich sequence (PAS) polypeptides as an alternative to PEG precipitants for protein crystallization.
Topics: Alanine; Crystallization; Crystallography, X-Ray; Hydrophobic and Hydrophilic Interactions; Muramidase; Peptides; Plant Proteins; Polyethylene Glycols; Proline; Protein O-Methyltransferase; Solubility | 2020 |
Natural Transmission of Bat-like Severe Acute Respiratory Syndrome Coronavirus 2 Without Proline-Arginine-Arginine-Alanine Variants in Coronavirus Disease 2019 Patients.
Topics: Alanine; Animals; Arginine; Chiroptera; COVID-19; Humans; Proline; SARS-CoV-2; Spike Glycoprotein, Coronavirus | 2021 |
New Proline, Alanine, Serine Repeat Sequence for Pharmacokinetic Enhancement of Anti-VEGF Single-Domain Antibody.
Topics: Alanine; Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Proliferation; Circular Dichroism; Half-Life; HEK293 Cells; Humans; Mice; Mice, Inbred BALB C; Proline; Protein Binding; Protein Structure, Secondary; Recombinant Fusion Proteins; Serine; Single-Domain Antibodies; Tissue Distribution; Vascular Endothelial Growth Factor A | 2020 |
Potential Repurposed Therapeutics and New Vaccines against COVID-19 and Their Clinical Status.
Topics: Adenosine Monophosphate; Alanine; Amides; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antiviral Agents; Chloroquine; Clinical Trials as Topic; COVID-19; COVID-19 Drug Treatment; COVID-19 Vaccines; Cyclopropanes; Drug Evaluation, Preclinical; Drug Repositioning; Humans; Isoindoles; Lactams; Lactams, Macrocyclic; Mice, Transgenic; Proline; Pyrazines; SARS-CoV-2; Small Molecule Libraries; Sulfonamides; Vaccines, Synthetic | 2020 |
Recognition of Potential COVID-19 Drug Treatments through the Study of Existing Protein-Drug and Protein-Protein Structures: An Analysis of Kinetically Active Residues.
Topics: Adenosine Monophosphate; Alanine; Angiotensin-Converting Enzyme 2; Antibodies, Viral; Antigen-Antibody Reactions; Antiviral Agents; Betacoronavirus; Binding Sites; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Repositioning; Eflornithine; Humans; Hydrophobic and Hydrophilic Interactions; Ivermectin; L-Lactate Dehydrogenase; Models, Molecular; Molecular Docking Simulation; Pandemics; Peptidyl-Dipeptidase A; Pneumonia, Viral; Proline; Protein Binding; Protein Conformation; Protein Interaction Mapping; Receptors, Glycine; Saposins; SARS-CoV-2; Sofosbuvir; Spike Glycoprotein, Coronavirus; Structure-Activity Relationship | 2020 |
Markov state modeling reveals alternative unbinding pathways for peptide-MHC complexes.
Topics: Alanine; Binding, Competitive; Computer Simulation; DNA Mutational Analysis; Major Histocompatibility Complex; Markov Chains; Models, Molecular; Mutation; Peptides; Proline; Protein Binding | 2020 |
Mycobacterium tuberculosis puromycin hydrolase displays a prolyl oligopeptidase fold and an acyl aminopeptidase activity.
Topics: Alanine; Aminopeptidases; Bacterial Proteins; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Gene Expression; Genetic Vectors; Hydrolases; Hydrophobic and Hydrophilic Interactions; Kinetics; Leucine; Models, Molecular; Mycobacterium tuberculosis; Phenylalanine; Proline; Prolyl Oligopeptidases; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Puromycin; Recombinant Proteins; Substrate Specificity | 2021 |
Metabolism of glutamic acid to alanine, proline, and γ-aminobutyric acid during takuan-zuke processing of radish root.
Topics: 4-Aminobutyrate Transaminase; Alanine; Desiccation; Food Handling; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamic Acid; Hydrogen-Ion Concentration; Plant Roots; Polymerase Chain Reaction; Proline; Raphanus; RNA, Plant; Sodium Chloride | 2021 |
Boceprevir, Calpain Inhibitors II and XII, and GC-376 Have Broad-Spectrum Antiviral Activity against Coronaviruses.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Caco-2 Cells; Carbonates; Cathepsin L; Cell Line; Chlorocebus aethiops; Coronavirus 229E, Human; Coronavirus 3C Proteases; Coronavirus NL63, Human; Coronavirus OC43, Human; COVID-19 Drug Treatment; Drug Combinations; Glycoproteins; HEK293 Cells; Humans; Leucine; Middle East Respiratory Syndrome Coronavirus; Oligopeptides; Proline; SARS-CoV-2; Serine Endopeptidases; Sulfonic Acids; Vero Cells | 2021 |
Chronological Metabolic Response to Intensive Phase TB Therapy in Patients with Cured and Failed Treatment Outcomes.
Topics: Alanine; Amino Acids; Humans; Isoleucine; Proline; Treatment Outcome | 2021 |
Divergent metabolomic profiles of cold-exposed mature and immature females of tropical versus temperate Drosophila species.
Topics: Acclimatization; Adaptation, Physiological; Alanine; Animals; Cold Temperature; Drosophila; Energy Metabolism; Female; Gas Chromatography-Mass Spectrometry; Gluconates; Glycerol; Lactones; Metabolomics; Principal Component Analysis; Proline; Reproduction; Seasons; Sex Factors; Species Specificity | 2021 |
Bacterial translation machinery for deliberate mistranslation of the genetic code.
Topics: Alanine; Amino Acid Sequence; Amino Acyl-tRNA Synthetases; Codon; Escherichia coli; Genetic Code; Proline; Protein Biosynthesis; RNA, Transfer, Amino Acyl; Sequence Homology; Streptomyces; Substrate Specificity | 2021 |
A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation.
Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; Arginine; C9orf72 Protein; Caenorhabditis elegans; Dipeptides; Female; Frontotemporal Dementia; Gene Editing; Gene Knockdown Techniques; Glycine; HEK293 Cells; Humans; Middle Aged; Motor Neurons; Nerve Degeneration; Proline | 2021 |
The pncA gene mutations of Mycobacterium tuberculosis in multidrug-resistant tuberculosis.
Topics: Adult; Alanine; Amidohydrolases; Antitubercular Agents; Aspartic Acid; Bacterial Proteins; Codon; Cross-Sectional Studies; Humans; Leucine; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Proline; Pyrazinamide; Tuberculosis, Multidrug-Resistant; Young Adult | 2022 |
Conformational preferences of Ac-Pro-azaXaa-NHMe (Xaa = Asn, Asp, Ala) and the effect of intramolecular hydrogen bonds on their stability in gas phase and solution.
Topics: Alanine; Asparagine; Aspartic Acid; Gases; Hydrogen Bonding; Models, Molecular; Proline; Protein Conformation; Protein Stability; Solutions | 2021 |
COVID-19 Therapeutics for Nonhospitalized Patients.
Topics: Adenosine Monophosphate; Alanine; Antibodies, Monoclonal, Humanized; Antibodies, Neutralizing; Antiviral Agents; Child; COVID-19 Drug Treatment; Cytidine; Drug Combinations; Female; Health Care Rationing; Humans; Hydroxylamines; Lactams; Leucine; Nitriles; Outpatients; Pregnancy; Proline; Ritonavir | 2022 |
Why scientists are racing to develop more COVID antivirals.
Topics: Adenosine Monophosphate; Administration, Oral; Alanine; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; COVID-19 Vaccines; Cytidine; Drug Approval; Drug Combinations; Drug Development; Drug Resistance, Viral; Drug Therapy, Combination; Hospitalization; Humans; Hydroxylamines; Lactams; Leucine; Medication Adherence; Molecular Targeted Therapy; Mutagenesis; Nitriles; Proline; Public-Private Sector Partnerships; Research Personnel; Ritonavir; SARS-CoV-2 | 2022 |
Synthesis of [1-8-NαC]-zanriorb A1, alanine-containing analogues, and their cytotoxic and anti-inflammatory activity.
Topics: Alanine; Anti-Inflammatory Agents; Antineoplastic Agents; Biological Products; Cyclization; Peptides, Cyclic; Proline | 2022 |
Remdesivir, Molnupiravir and Nirmatrelvir remain active against SARS-CoV-2 Omicron and other variants of concern.
Topics: Adenosine; Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Coronavirus 3C Proteases; COVID-19 Drug Treatment; Cytidine; Humans; Hydroxylamines; Lactams; Leucine; Microbial Sensitivity Tests; Nitriles; Proline; RNA-Dependent RNA Polymerase; SARS-CoV-2; Vero Cells; Virus Replication | 2022 |
Treatment of COVID-19 in high-risk outpatients.
Topics: Adenosine Monophosphate; Alanine; Ambulatory Care; Antibodies, Monoclonal, Humanized; Antibodies, Neutralizing; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Cytidine; Drug Combinations; Humans; Hydroxylamines; Lactams; Leucine; Nitriles; Outpatients; Proline; Ritonavir; Treatment Outcome | 2022 |
Plasma d-amino acids are associated with markers of immune activation and organ dysfunction in people with HIV.
Topics: Alanine; Amino Acids; Asparagine; Biomarkers; HIV Infections; Humans; Multiple Organ Failure; Proline; Serine | 2022 |
Fluctuations in Metabolites and Bone Markers Across the Menstrual Cycle in Eumenorrheic Women and Oral Contraceptive Users.
Topics: Alanine; Contraceptives, Oral; Cross-Sectional Studies; Female; Glutamine; Glycine; Humans; Menstrual Cycle; Proline; Tyrosine | 2022 |
Chiral resolution of plasma amino acids reveals enantiomer-selective associations with organ functions.
Topics: Alanine; Amino Acids; Chromatography, High Pressure Liquid; Humans; Proline; Stereoisomerism | 2022 |
Hundreds of COVID trials could provide a deluge of new drugs.
Topics: Adenosine Monophosphate; Administration, Oral; Alanine; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Neutralizing; Antiviral Agents; Clinical Trials as Topic; COVID-19; COVID-19 Drug Treatment; COVID-19 Vaccines; Cytidine; Depsipeptides; Dexamethasone; Drug Combinations; Drug Repositioning; Drug Synergism; Esters; Guanidines; Hospitalization; Host-Pathogen Interactions; Humans; Hydroxylamines; Internationality; Lactams; Leucine; Mice; National Institutes of Health (U.S.); Nitriles; Peptide Elongation Factor 1; Peptides, Cyclic; Proline; Protease Inhibitors; Ritonavir; RNA-Dependent RNA Polymerase; SARS-CoV-2; Serine Endopeptidases; Sodium-Glucose Transporter 2 Inhibitors; United States; Virus Replication | 2022 |
Isolation and characterization of novel antihypertensive bioactive peptides from brassica napus and angiotensin-converting enzyme (ace) inhibition potential.
Topics: Alanine; Angiotensins; Antihypertensive Agents; Arginine; Brassica napus; Cysteine; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptides; Peptidyl-Dipeptidase A; Phenylalanine; Proline; Tandem Mass Spectrometry; Threonine; Tyrosine; Valine | 2022 |
Plant-exclusive domain of trans-editing enzyme ProXp-ala confers dimerization and enhanced tRNA binding.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Arabidopsis; Escherichia coli; Plant Proteins; Proline; Protein Biosynthesis; Protein Conformation, alpha-Helical; Protein Domains; Protein Multimerization; RNA, Transfer | 2022 |
Metabolomic profiles to explore biomarkers of severe sarcopenia in older men: A pilot study.
Topics: Aged; Aged, 80 and over; Alanine; Biomarkers; Cohort Studies; Cross-Sectional Studies; Humans; Male; Pilot Projects; Proline; Sarcopenia; Tryptophan | 2022 |
Amino acids, microbiota-related metabolites, and the risk of incident diabetes among normoglycemic Chinese adults: Findings from the 4C study.
Topics: 2-Aminoadipic Acid; Adult; Alanine; Amino Acids; Asparagine; Diabetes Mellitus, Type 2; Glutamic Acid; Histidine; Homoserine; Humans; Lipids; Methionine; Microbiota; Proline; Uric Acid | 2022 |
Investigation of the role of prolines 232/233 in RTPPK motif in tau protein aggregation: An in vitro study.
Topics: Alanine; Alzheimer Disease; Humans; Mutant Proteins; Proline; Protein Aggregates; tau Proteins | 2022 |
Phenotype microarray analysis reveals the biotransformation of Fusarium oxysporum f.sp. lycopersici influenced by Bacillus subtilis PBE-8 metabolites.
Topics: Alanine; Ammonia; Antifungal Agents; Arginine; Aspartic Acid; Bacillus subtilis; Biotransformation; Carbon; Fusarium; Glutamic Acid; Glutamine; Glycine; Isoleucine; Leucine; Linoleic Acids; Linolenic Acids; Microarray Analysis; Nitrogen; Phenotype; Plant Diseases; Proline; RNA, Transfer; Solanum lycopersicum; Valine | 2022 |
Recent strains of influenza D virus create a new genetic cluster for European strains.
Topics: Alanine; Animals; Arginine; Asparagine; Aspartic Acid; Cattle; Cattle Diseases; Glycine; Nucleotides; Orthomyxoviridae; Orthomyxoviridae Infections; Phylogeny; Proline; Serine; Thogotovirus; Threonine; Valine | 2022 |
Proline/Glycine residues of the PG-levels guide conformational changes along the transport cycle in the mitochondrial carnitine/acylcarnitine carrier (SLC25A20).
Topics: Alanine; Carnitine; Carnitine Acyltransferases; Glycine; Proline | 2022 |
WNK1/HSN2 mediates neurite outgrowth and differentiation via a OSR1/GSK3β-LHX8 pathway.
Topics: Alanine; Cholinergic Agents; Glycogen Synthase Kinase 3 beta; Hereditary Sensory and Autonomic Neuropathies; Humans; LIM-Homeodomain Proteins; Neuronal Outgrowth; Proline; Protein Serine-Threonine Kinases; Transcription Factors; WNK Lysine-Deficient Protein Kinase 1 | 2022 |
Computational analysis and functional characterisation of Tor putitora toll-like receptor 4 with the elucidation of its binding sites for microbial mimicking ligands.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Carps; Cyprinidae; DNA, Complementary; Fish Proteins; Leucine; Ligands; Molecular Docking Simulation; Myeloid Differentiation Factor 88; Pathogen-Associated Molecular Pattern Molecules; Phylogeny; Proline; Receptors, Interleukin-1; Toll-Like Receptor 4; Tumor Necrosis Factor Receptor-Associated Peptides and Proteins | 2022 |
[Determination of free amino acids in Eriocheir sinensis by ultra-high performance liquid chromatography-high resolution mass spectrometry].
Topics: Acetonitriles; Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brachyura; Chromatography, High Pressure Liquid; Cystine; Formates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Mass Spectrometry; Methionine; Perchlorates; Phenylalanine; Polypropylenes; Proline; Serine; Solvents; Threonine; Tyrosine; Valine; Water | 2022 |
Metabolomics analysis of stool in rats with type 2 diabetes mellitus after single-anastomosis duodenal-ileal bypass with sleeve gastrectomy.
Topics: Alanine; Amino Acids, Aromatic; Amino Acids, Branched-Chain; Anastomosis, Surgical; Animals; Bile Acids and Salts; Blood Glucose; Diabetes Mellitus, Type 2; Gastrectomy; Glutamates; Glycated Hemoglobin; Ileum; Isobutyrates; Lithocholic Acid; Obesity, Morbid; Phenylalanine; Phospholipids; Proline; Rats; Streptozocin; Valine | 2022 |
Multi-Omics Analysis Revealed a Significant Alteration of Critical Metabolic Pathways Due to Sorafenib-Resistance in Hep3B Cell Lines.
Topics: Alanine; Amino Acids; Antineoplastic Agents; Biomarkers; Calpain; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Folic Acid Antagonists; Glucose; Humans; L-Iditol 2-Dehydrogenase; Liver Neoplasms; Metabolic Networks and Pathways; Nucleotides; Phosphatidylcholines; Proline; Protein Kinase Inhibitors; Proteome; Proteomics; Sorafenib; Succinic Acid; Superoxide Dismutase; Tyrosine; Ubiquitin Thiolesterase; Uridine Diphosphate | 2022 |
Efficient secretory production of proline/alanine/serine (PAS) biopolymers in Corynebacterium glutamicum yielding a monodisperse biological alternative to polyethylene glycol (PEG).
Topics: Alanine; Amino Acids; Biopolymers; Corynebacterium glutamicum; Peptides; Polyethylene Glycols; Proline; Serine | 2022 |
Molecular mechanism of Tsukamurella tyrosinosolvens strain P9 in response to root exudates of peanut.
Topics: Alanine; Amino Acids; Arachis; Arginine; Exudates and Transudates; Plant Roots; Proline; Siderophores | 2023 |
NKCC transport mediates the insulinotropic effects of taurine and other small neutral amino acids.
Topics: Alanine; Amino Acids, Neutral; Animals; Cell Line; Glucose; Humans; Hypoglycemic Agents; Insulin; Islets of Langerhans; Mice; Proline; Taurine | 2023 |
Application of Amino Acids for High-Dosage Measurements with Electron Paramagnetic Resonance Spectroscopy.
Topics: Alanine; Amino Acids; Cysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Proline | 2023 |
Metabolomics profiling of seminal plasma in obesity-induced asthenozoospermia.
Topics: Aconitic Acid; Alanine; Asthenozoospermia; Citrulline; Glucose; Glutamic Acid; Glycine; Humans; Leucine; Lysine; Male; Metabolomics; Phenylalanine; Proline; Semen; Serine; Succinic Acid; Threonine; Tyrosine; Valine | 2023 |
Topics: Alanine; Animals; Arginine; Cyclophosphamide; Glycine; Magnetic Resonance Spectroscopy; Metabolomics; Mice; Proline; Proton Magnetic Resonance Spectroscopy | 2023 |
Mechanistic insights into the lignin dissolution behavior in amino acid based deep eutectic solvents.
Topics: Alanine; Amino Acids; Biomass; Carboxylic Acids; Deep Eutectic Solvents; Lignin; Proline; Solubility; Solvents | 2023 |
Improving the isolated microspore culture in eggplant (Solanum melongena L.) with amino acid nutrition.
Topics: Alanine; Amino Acids; Glutamine; Proline; Serine; Solanum melongena | 2023 |
Automated Fast-Flow Synthesis of Chromosome 9 Open Reading Frame 72 Dipeptide Repeat Proteins.
Topics: Alanine; Arginine; C9orf72 Protein; Chromosomes, Human, Pair 9; Dipeptides; Glycine; Humans; Open Reading Frames; Proline; Proteins | 2023 |
Uncovering the Molecular Mechanisms of Cosolvency and Predicting the Cosolvency Phenomenon by Molecular Simulations: A Case Study of Amino Acids.
Topics: Alanine; Amino Acids; Phenylalanine; Proline; Tryptophan | 2023 |
Analysis of thermostability for seven Phe to Ala and six Pro to Gly mutants in the Fab constant region of adalimumab.
Topics: Adalimumab; Alanine; Mutagenesis, Site-Directed; Phenylalanine; Proline; Protein Conformation | 2023 |
Surface-Enhanced Raman Scattering Enantioselective Detection of Gastric Cancer-Related d-Amino Acids in Saliva Based on Enzyme-Mediated Cascade Reaction.
Topics: Alanine; Amino Acids; Antifibrinolytic Agents; Humans; Hydrogen Peroxide; Proline; Saliva; Spectrum Analysis, Raman; Stereoisomerism; Stomach Neoplasms | 2023 |
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |