alanine and phosphotyrosine

alanine has been researched along with phosphotyrosine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (33.33)18.2507
2000's6 (50.00)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alessi, DR; Cohen, P; Shaw, M1
Keegan, AD; Wang, HY; Zamorano, J1
Bradshaw, JM; Waksman, G1
Glover, NR; Tracey, AS1
Burke, TR; Miyoshi, K; Otaka, A; Wu, L; Yao, ZJ; Ye, B; Zhang, ZY1
Chen, Z; Hamilton, AD; Haura, E; Jove, R; Kim, JS; Laudano, A; Ryan, D; Sebti, S; Turkson, J; Zhang, Y1
Calderwood, DA; de Pereda, JM; Fujioka, Y; GarcĂ­a-Alvarez, B; Ginsberg, MH; Liddington, RC; Margolis, B; McGlade, CJ; Nakamoto, T1
Ayrapetov, MK; Lee, S; Lin, X; Parang, K; Sun, G1
Argetsinger, LS; Carter-Su, C; Cline, JM; Jensen, ON; Kouadio, JL; Mazurkiewicz-Munoz, AM; Stensballe, A1
Bindu, L; Burke, TR; Fisher, RJ; Jiang, S; Li, P; Nicklaus, M; Peach, ML; Roller, PP; Worthy, KW1
Jackson, RF; Lilley, M; Mambwe, B; Muimo, R1
Asai, A; Inoue, Y; Iwamoto, K; Matsuno, K; Muraoka, D; Ogo, N; Taguchi, K; Uehara, Y1

Other Studies

12 other study(ies) available for alanine and phosphotyrosine

ArticleYear
Further evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216.
    FEBS letters, 1997, Oct-27, Volume: 416, Issue:3

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Alanine; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Insulin; Insulin-Like Growth Factor I; Isoenzymes; Mutagenesis, Site-Directed; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Transfection; Tyrosine

1997
A role for the insulin-interleukin (IL)-4 receptor motif of the IL-4 receptor alpha-chain in regulating activation of the insulin receptor substrate 2 and signal transducer and activator of transcription 6 pathways. Analysis by mutagenesis.
    The Journal of biological chemistry, 1998, Apr-17, Volume: 273, Issue:16

    Topics: Alanine; Amino Acid Sequence; Animals; Conserved Sequence; DNA-Binding Proteins; Humans; Insulin Receptor Substrate Proteins; Interleukin-4; Intracellular Signaling Peptides and Proteins; Lymphoma, B-Cell; Macromolecular Substances; Mice; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoproteins; Phosphotyrosine; Point Mutation; Receptor, Insulin; Receptors, IgE; Receptors, Interleukin-4; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; src Homology Domains; STAT4 Transcription Factor; Trans-Activators; Transfection; Tumor Cells, Cultured; Tyrosine

1998
Calorimetric examination of high-affinity Src SH2 domain-tyrosyl phosphopeptide binding: dissection of the phosphopeptide sequence specificity and coupling energetics.
    Biochemistry, 1999, Apr-20, Volume: 38, Issue:16

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Calorimetry; Glutamic Acid; Hot Temperature; Humans; Isoleucine; Mutagenesis, Site-Directed; Peptide Fragments; Phosphopeptides; Phosphotyrosine; Protein Binding; src Homology Domains; Thermodynamics

1999
Nuclear magnetic resonance and restrained molecular dynamics studies of the interaction of an epidermal growth factor-derived peptide with protein tyrosine phosphatase 1B.
    Biochemistry, 1999, Apr-20, Volume: 38, Issue:16

    Topics: Alanine; Aspartic Acid; Binding, Competitive; Crystallography, X-Ray; ErbB Receptors; Glutamic Acid; Leucine; Ligands; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Phenylalanine; Phosphotyrosine; Protein Binding; Protein Conformation; Protein Tyrosine Phosphatases; Temperature; Thermodynamics

1999
Phospho-Azatyrosine, a less effective protein-tyrosine phosphatase substrate than phosphotyrosine.
    Bioorganic & medicinal chemistry letters, 2001, May-21, Volume: 11, Issue:10

    Topics: Alanine; Animals; Anticarcinogenic Agents; Catalytic Domain; Drug Design; Enzyme Inhibitors; Humans; Kinetics; Molecular Mimicry; Peptides; Phosphotyrosine; Protein Tyrosine Phosphatases; Structure-Activity Relationship; Substrate Specificity

2001
Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation.
    The Journal of biological chemistry, 2001, Nov-30, Volume: 276, Issue:48

    Topics: 3T3 Cells; Alanine; Animals; Baculoviridae; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Cytokines; Cytosol; Dimerization; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Design; Gene Expression Regulation; Growth Substances; Insecta; Luciferases; Mice; Models, Biological; Mutation; Peptides; Phosphopeptides; Phosphotyrosine; Plasmids; Protein Binding; Protein Structure, Tertiary; Signal Transduction; src Homology Domains; STAT3 Transcription Factor; Time Factors; Trans-Activators; Transcription, Genetic; Transfection

2001
Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Mar-04, Volume: 100, Issue:5

    Topics: Alanine; Amino Acid Sequence; Animals; CHO Cells; Cricetinae; Cytoplasm; Databases as Topic; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Humans; Integrin beta Chains; Integrins; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Signal Transduction; Transfection; Tyrosine

2003
Probing the communication between the regulatory and catalytic domains of a protein tyrosine kinase, Csk.
    Biochemistry, 2005, Feb-08, Volume: 44, Issue:5

    Topics: Alanine; Animals; Catalytic Domain; Chickens; Crystallography, X-Ray; CSK Tyrosine-Protein Kinase; Enzyme Activation; Phenylalanine; Phosphopeptides; Phosphotyrosine; Point Mutation; Protein Conformation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Sequence Alignment; Sequence Deletion; src Homology Domains; src-Family Kinases; Substrate Specificity; Tryptophan

2005
Phosphorylation of JAK2 at serine 523: a negative regulator of JAK2 that is stimulated by growth hormone and epidermal growth factor.
    Molecular and cellular biology, 2006, Volume: 26, Issue:11

    Topics: 3T3 Cells; Alanine; Animals; Butadienes; Cells, Cultured; Chlorocebus aethiops; COS Cells; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Growth Hormone; Humans; Janus Kinase 2; MAP Kinase Kinase 1; Mass Spectrometry; Mice; Mutation; Nitriles; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Repressor Proteins; STAT5 Transcription Factor; Tetradecanoylphorbol Acetate

2006
Structure-based design of potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics.
    Biochemical and biophysical research communications, 2006, Oct-20, Volume: 349, Issue:2

    Topics: Alanine; Animals; Chemistry, Pharmaceutical; Drug Design; GRB2 Adaptor Protein; Humans; Inhibitory Concentration 50; Mice; Peptides; Phosphotyrosine; Protein Binding; Protein-Tyrosine Kinases; src Homology Domains

2006
4-Phosphothiophen-2-yl alanine: a new 5-membered analogue of phosphotyrosine.
    Chemical communications (Cambridge, England), 2014, Aug-25, Volume: 50, Issue:66

    Topics: Alanine; Blotting, Western; Phosphorylation; Phosphotyrosine

2014
Inhibition of STAT3 by Anticancer Drug Bendamustine.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Alanine; Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Binding Sites; Cell Line, Tumor; Cysteine; Drug Screening Assays, Antitumor; Gene Expression; Humans; Peptides; Phosphotyrosine; Point Mutation; Protein Binding; src Homology Domains; STAT3 Transcription Factor; Structure-Activity Relationship

2017