Compounds > alanine

alanine and phosphoramidic acid

alanine has been researched along with phosphoramidic acid in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's4 (50.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Ballatore, C; Balzarini, J; Bidois, L; De Clercq, E; Hiouni, A; McGuigan, C1
Balzarini, J; Cahard, D; Gilbert, IH; Harris, SA; Heshmati, P; Knaggs, MH; McGuigan, C1
Ballatore, C; Balzarini, J; De Clercq, E; McGuigan, C1
Aiba, Y; Beigelman, L; Blatt, L; Leisvuori, A; Lönnberg, H; Lönnberg, T; Poijärvi-Virta, P1
Battina, SK; Bleiman, B; Bourdin, C; Brancale, A; Bryant, KD; Chamberlain, S; Ganguly, B; Gorovits, E; Henson, G; Hunley, D; Hutchins, J; Kolykhalov, A; McGuigan, C; Muhammad, J; Obikhod, A; Patti, J; Ramamurty, CV; Srivinas Rao, C; Vernachio, J; Walters, CR; Wang, J1
Bannister, R; Barauskas, O; Bavari, S; Carra, E; Chun, K; Cihlar, T; Clarke, MO; Doerffler, E; Feng, JY; Hui, HC; Jordan, R; Knox, J; Lee, G; Lee, WA; Lew, W; Lo, MK; Mackman, RL; Neville, S; Perron, M; Perry, J; Ray, AS; Rheingold, AL; Ross, B; Siegel, D; Soloveva, V; Stray, KM; Strickley, R; Swaminathan, S; Wang, Q; Warren, TK; Wolfe, L; Xu, Y; Zhang, L1
De Clercq, E1
Egli, M; Jovanovic, D; Pallan, PS; Richert, C; Tremmel, P1

Reviews

1 review(s) available for alanine and phosphoramidic acid

ArticleYear
New Nucleoside Analogues for the Treatment of Hemorrhagic Fever Virus Infections.
    Chemistry, an Asian journal, 2019, Nov-18, Volume: 14, Issue:22

    Topics: Adenine; Adenosine; Alanine; Amides; Antiviral Agents; Base Pairing; Ebolavirus; Guanine; Hemorrhagic Fevers, Viral; Humans; Nucleotides; Phosphoric Acids; Pyrazines; Triazines

2019

Other Studies

7 other study(ies) available for alanine and phosphoramidic acid

ArticleYear
Phosphoramidate derivatives of stavudine as inhibitors of HIV: unnatural amino acids may substitute for alanine.
    Antiviral chemistry & chemotherapy, 2000, Volume: 11, Issue:2

    Topics: Alanine; Amides; Amino Acid Substitution; Amino Acids; Anti-HIV Agents; Cell Line; HIV-1; HIV-2; Humans; Phosphoric Acids; Reverse Transcriptase Inhibitors; Stavudine; Structure-Activity Relationship

2000
A QSAR study investigating the effect of L-alanine ester variation on the anti-HIV activity of some phosphoramidate derivatives of d4T.
    Bioorganic & medicinal chemistry letters, 2000, Sep-18, Volume: 10, Issue:18

    Topics: Alanine; Amides; Anti-HIV Agents; Cell Death; HIV-1; HIV-2; Models, Chemical; Models, Molecular; Phosphoric Acids; Quantitative Structure-Activity Relationship; Stavudine; Structure-Activity Relationship

2000
Synthesis and evaluation of novel amidate prodrugs of PMEA and PMPA.
    Bioorganic & medicinal chemistry letters, 2001, Apr-23, Volume: 11, Issue:8

    Topics: Adenine; Alanine; Amides; Antiviral Agents; Drug Stability; Esterases; Humans; Nucleotides; Organophosphonates; Organophosphorus Compounds; Phosphoric Acids; Prodrugs; Retroviridae; Structure-Activity Relationship; Tenofovir

2001
Chemical and enzymatic stability of amino acid derived phosphoramidates of antiviral nucleoside 5'-monophosphates bearing a biodegradable protecting group.
    Organic & biomolecular chemistry, 2010, May-07, Volume: 8, Issue:9

    Topics: Acetates; Alanine; Amides; Animals; Antiviral Agents; Cytidine Monophosphate; Enzyme Stability; Esterases; Humans; Kinetics; Liver; Male; Malonates; Molecular Structure; Phosphoric Acids; Prostatic Neoplasms; Ribavirin; Swine; Time Factors

2010
Synthesis and evaluation against hepatitis C virus of 7-deaza analogues of 2'-C-methyl-6-O-methyl guanosine nucleoside and L-Alanine ester phosphoramidates.
    Bioorganic & medicinal chemistry letters, 2013, Apr-01, Volume: 23, Issue:7

    Topics: Alanine; Amides; Antiviral Agents; Esters; Guanine; Hepacivirus; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Phosphoric Acids

2013
Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses.
    Journal of medicinal chemistry, 2017, 03-09, Volume: 60, Issue:5

    Topics: Adenosine Monophosphate; Alanine; Amides; Cell Line; Drug Discovery; Hemorrhagic Fever, Ebola; Humans; Microbial Sensitivity Tests; Phosphoric Acids; Prodrugs; Ribonucleotides; Structure-Activity Relationship; Virus Diseases

2017
The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid.
    Angewandte Chemie (International ed. in English), 2020, 11-02, Volume: 59, Issue:45

    Topics: Adenosine Monophosphate; Alanine; Amides; Amino Acids; Antiviral Agents; Catalytic Domain; COVID-19; COVID-19 Drug Treatment; Crystallography, X-Ray; Half-Life; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Molecular Dynamics Simulation; Nucleotides; Phosphoric Acids; Ribonuclease, Pancreatic; SARS-CoV-2

2020