alanine has been researched along with oxadiazoles in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (53.13) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (12.50) | 29.6817 |
| 2010's | 4 (12.50) | 24.3611 |
| 2020's | 7 (21.88) | 2.80 |
| Authors | Studies |
|---|---|
| Walker, RJ | 1 |
| Anderson, CR; Cull-Candy, SG; Miledi, R | 2 |
| Davies, J; Evans, RH; Francis, AA; Watkins, JC | 1 |
| Mori, A; Sakai, A; Takeuchi, H; Yokoi, I | 1 |
| Lancet, D; Pecht, I | 1 |
| Arihara, S; Koike, K; Nakajima, T; Takemoto, T | 2 |
| Ishida, M; Shinozaki, H | 2 |
| Ross, SM; Roy, DN; Spencer, PS | 1 |
| Johnson, BG; Schoepp, DD | 1 |
| Aley, SB; Breuer, WV; Cabantchik, ZI; Ginsburg, H; Kutner, S | 1 |
| Shibuya, I; Shinozaki, H | 1 |
| Shinozaki, H | 1 |
| Bornstein, JC; Curtis, DR; Johnston, GA; Lodge, D | 1 |
| Davies, J; Evans, RH; Francis, AA; Jones, AW; Watkins, JC | 1 |
| Hatakeyama, S; Inoue, T; Ito, K; Nakamura, KT; Tanaka, N; Tozaka, T; Yoshimoto, T | 1 |
| Bai, F; Chen, Z; Feng, L | 1 |
| Rothkegel, C; Schmidt, PM; Schröder, H; Stasch, JP; Wunder, F | 1 |
| Ma, LH; Takanishi, CL; Wood, MJ | 1 |
| Atchison, K; Becker, SL; Efremov, I; Hallgren, AJ; Lu, Y; Miller, EH; Nolan, CE; Osgood, SM; Pustilnik, LR; Riddell, D; Robshaw, AE; Stepan, AF; Subramanyam, C; Zhang, L | 1 |
| Dumin, JA; Loureiro, RM; McKee, TD; Tate, B; Zarayskiy, V | 1 |
| Kalle, AM; Pedada, SR; Pidugu, VR; Satya, AK; Yarla, NS | 1 |
| Bishayee, A; Kalle, AM; Pidugu, VR; Satya, AK; Yarla, NS | 1 |
| Müller, T | 1 |
| Ge, S; Guyatt, G; Lu, L; Tang, C; Wang, S; Wen, H; Xu, M; Xu, N; Yao, G; Zeng, J; Zhang, Y; Zheng, X | 1 |
| Guo, X; Lei, J; Shi, Y; Yan, C; Yang, G; Zhou, R | 1 |
| Hussar, DA | 1 |
| Larson, D; Simuni, T | 1 |
| Al-Harrasi, A; Halim, SA; Khan, A; Khan, M; Rafiq, K; Ur Rehman, N | 1 |
| Cardoza, S; Chatterjee, AK; Mandal, A; Riva, L; Shrivash, MK; Tandon, V | 1 |
4 review(s) available for alanine and oxadiazoles
| Article | Year |
|---|---|
The pharmacology of the excitatory neuromuscular junction in the crayfish.
Topics: Alanine; Alkaloids; Animals; Astacoidea; Concanavalin A; Diltiazem; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Histamine H1 Antagonists; Kainic Acid; Neuromuscular Blocking Agents; Neuromuscular Junction; Oxadiazoles; Quisqualic Acid; Ribonucleotides; Structure-Activity Relationship | 1980 |
Safinamide in the treatment of Parkinson's disease.
Topics: Adolescent; Adult; Alanine; Antiparkinson Agents; Benzylamines; Catechol O-Methyltransferase Inhibitors; Female; Humans; Levodopa; Male; Middle Aged; Oxadiazoles; Parkinson Disease; Young Adult | 2020 |
Anti-Aβ agents for mild to moderate Alzheimer's disease: systematic review and meta-analysis.
Topics: Acitretin; Alanine; Alzheimer Disease; Amyloid beta-Peptides; Antibodies, Monoclonal, Humanized; Anxiety; Azepines; Clioquinol; Copper; Cyclic S-Oxides; Depression; Diarrhea; Exanthema; Fatigue; Flurbiprofen; Humans; Immunoglobulins, Intravenous; Inositol; Mental Status and Dementia Tests; Minimal Clinically Important Difference; Orotic Acid; Oxadiazoles; Severity of Illness Index; Sulfonamides; Syncope; Thiadiazines; Treatment Outcome; Vomiting | 2020 |
New dopaminergic therapies for PD motor complications.
Topics: Alanine; Antiparkinson Agents; Apomorphine; Benzylamines; Delayed-Action Preparations; Disease Progression; Dopamine Agents; Dopamine Agonists; Drug Compounding; Drug Delivery Systems; Dyskinesias; Humans; Levodopa; Oxadiazoles; Parkinson Disease | 2022 |
28 other study(ies) available for alanine and oxadiazoles
| Article | Year |
|---|---|
The action of kainic acid and quisqualic acid on the glutamate receptors of three identifiable neurones from the brain of the snail, Helix aspersa.
Topics: Alanine; Amino Acids, Dicarboxylic; Animals; Brain; Glutamates; Helix, Snails; Neurons; Oxadiazoles; Pyrrolidines; Receptors, Drug; Snails | 1976 |
Glutamate current noise: post-synaptic channel kinetics investigated under voltage clamp.
Topics: Alanine; Animals; Electric Conductivity; Glutamates; Grasshoppers; In Vitro Techniques; Ion Channels; Kinetics; Membrane Potentials; Neuromuscular Junction; Oxadiazoles; Receptors, Drug; Synaptic Transmission; Temperature | 1978 |
Excitatory amino acid receptors and synaptic excitation in the mammalian central nervous system.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Glutamates; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Neurotransmitter; Spinal Nerve Roots | 1979 |
Effects of ibotenic acid, quisqualic acid and their relatives on the excitability of an identifiable giant neurone of an African giant snail (Achatina fulica Férussac).
Topics: Alanine; Animals; Glutamates; Ibotenic Acid; Neurons; Oxadiazoles; Oxazoles; Snails; Structure-Activity Relationship | 1977 |
Spectroscopic and immunochemical studies with nitrobenzoxadiazolealanine, a fluorescent dinitrophenyl analogue.
Topics: 4-Chloro-7-nitrobenzofurazan; Alanine; Antibodies; Binding Sites, Antibody; Circular Dichroism; Fluorescent Dyes; Oxadiazoles; Spectrometry, Fluorescence; Spectrophotometry | 1977 |
[Studies on the constituents of Quisqualis Fructus. II. Structure of quisqualic acid (author's transl)].
Topics: Alanine; Oxadiazoles; Plants; Propionates | 1975 |
[Studies on the constituents of Quisqualis fructus. III. synthesis of quisqualic acid and the related compounds (author's transl)].
Topics: Alanine; Oxadiazoles; Plants, Medicinal; Urea | 1975 |
Glutamate and quisqualate noise in voltage-clamped locust muscle fibres.
Topics: Alanine; Animals; Electric Conductivity; Glutamates; Grasshoppers; In Vitro Techniques; Membrane Potentials; Muscles; Neuromuscular Junction; Oxadiazoles; Receptors, Drug; Sodium; Structure-Activity Relationship; Temperature | 1976 |
Inhibition of quisqualate responses by domoic or kainic acid in crayfish opener muscle.
Topics: Alanine; Animals; Dose-Response Relationship, Drug; Glutamates; Membrane Potentials; Muscles; Oxadiazoles; Pyrrolidines | 1976 |
Beta-N-oxalylamino-L-alanine action on glutamate receptors.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Aspartic Acid; beta-Alanine; Binding, Competitive; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Oxadiazoles; Piperazines; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Synaptic Membranes; Thiocyanates | 1989 |
Inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in the neonatal rat hippocampus by 2-amino-3-phosphonopropionate.
Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Carbachol; Chlorides; Hippocampus; Hydrolysis; Ibotenic Acid; In Vitro Techniques; Inositol; Kainic Acid; Kinetics; Lithium; Lithium Chloride; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains | 1989 |
Characterization of permeation pathways in the plasma membrane of human erythrocytes infected with early stages of Plasmodium falciparum: association with parasite development.
Topics: Alanine; Animals; Cell Membrane Permeability; Cell Separation; Centrifugation, Density Gradient; Erythrocyte Membrane; Fluorescent Dyes; Humans; Malaria; Oxadiazoles; Plasmodium falciparum; Povidone; Silicon Dioxide; Sorbitol; Taurine; Temperature | 1985 |
A new potent excitant, quisqualic acid: effects on crayfish neuromuscular junction.
Topics: Action Potentials; Alanine; Animals; Astacoidea; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; Electrophoresis; Glutamates; In Vitro Techniques; Iontophoresis; Membrane Potentials; Microelectrodes; Nerve Endings; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Oxadiazoles; Plants; Receptors, Drug; Sensory Receptor Cells | 1974 |
In vivo inactivation of quisqualate: studies in the cat spinal cord.
Topics: Alanine; Amino Acids; Animals; Cats; Ganglia, Spinal; Interneurons; Oxadiazoles; Quisqualic Acid; Receptors, Neurotransmitter; Synaptic Transmission | 1980 |
Electrophysiological studies of kainate, quisqualate, and ibotenate action on the crayfish neuromuscular junction.
Topics: Alanine; Animals; Astacoidea; Electrophysiology; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Neuromuscular Junction; Oxadiazoles; Oxazoles; Picrotoxin; Pyrrolidines; Quisqualic Acid | 1981 |
Antagonism of excitatory amino acid-induced and synaptic excitation of spinal neurones by cis-2,3-piperidine dicarboxylate.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cats; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Rana temporaria; Rats; Spinal Cord; Synapses | 1981 |
Novel inhibitor for prolyl aminopeptidase from Serratia marcescens and studies on the mechanism of substrate recognition of the enzyme using the inhibitor.
Topics: Alanine; Amino Acid Sequence; Aminopeptidases; Crystallography, X-Ray; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Hydrolysis; Macromolecular Substances; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxadiazoles; Proline; Recombinant Proteins; Serratia marcescens; Substrate Specificity | 2003 |
Photophysical processes of a fluorene derivative containing 1,3,4-oxadiazole.
Topics: Absorption; Alanine; Fluorenes; Molecular Structure; Nanotubes, Carbon; Oxadiazoles; Photochemistry; Solvents; Spectrometry, Fluorescence | 2004 |
Residues stabilizing the heme moiety of the nitric oxide sensor soluble guanylate cyclase.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Benzoates; Binding Sites; CHO Cells; Cricetinae; Cricetulus; Cyclic GMP; Diethylamines; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Genotype; Guanylate Cyclase; Heme; Molecular Sequence Data; Mutation, Missense; Nitric Acid; Nitrogen Oxides; Oxadiazoles; Protoporphyrins; Pyrazoles; Pyridines; Quinoxalines; Sequence Homology, Amino Acid; Serine; Solubility; Transfection | 2005 |
Molecular mechanism of oxidative stress perception by the Orp1 protein.
Topics: Alanine; Binding Sites; Cysteine; Disulfides; Genetic Complementation Test; Glutathione Peroxidase; Hydrogen Bonding; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Mutation; Oxadiazoles; Oxidation-Reduction; Oxidative Stress; Phenylalanine; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sulfenic Acids; Transcription Factors | 2007 |
Quantitative pharmacokinetic/pharmacodynamic analyses suggest that the 129/SVE mouse is a suitable preclinical pharmacology model for identifying small-molecule γ-secretase inhibitors.
Topics: Alanine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Azepines; Brain; Drug Discovery; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Mice; Mice, 129 Strain; Mice, Transgenic; Models, Animal; Oxadiazoles; Small Molecule Libraries; Sulfonamides | 2011 |
An improved cell-based method for determining the γ-secretase enzyme activity against both Notch and APP substrates.
Topics: Alanine; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Azepines; Cell Line; Enzyme Inhibitors; Humans; Oxadiazoles; Receptors, Notch; Solid Phase Extraction; Substrate Specificity; Sulfonamides; Thiophenes | 2013 |
Design and synthesis of novel HDAC8 inhibitory 2,5-disubstituted-1,3,4-oxadiazoles containing glycine and alanine hybrids with anti cancer activity.
Topics: Alanine; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Glycine; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Molecular Structure; Oxadiazoles; Repressor Proteins; Structure-Activity Relationship; Tumor Cells, Cultured | 2016 |
Novel histone deacetylase 8-selective inhibitor 1,3,4-oxadiazole-alanine hybrid induces apoptosis in breast cancer cells.
Topics: Acetylation; Alanine; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; CDC2 Protein Kinase; Cell Line; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Histone Deacetylases; Histones; Humans; Inhibitory Concentration 50; K562 Cells; MCF-7 Cells; Organ Specificity; Oxadiazoles; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Repressor Proteins; Signal Transduction | 2017 |
Structural basis of γ-secretase inhibition and modulation by small molecule drugs.
Topics: Alanine; Amino Acid Sequence; Amyloid Precursor Protein Secretases; Azepines; Binding Sites; Cryoelectron Microscopy; Enzyme Inhibitors; HEK293 Cells; Humans; Models, Biological; Models, Molecular; Oxadiazoles; Pharmaceutical Preparations; Presenilin-1; Protein Binding; Protein Conformation; Small Molecule Libraries; Structure-Activity Relationship; Substrate Specificity; Sulfonamides | 2021 |
New Drugs 2021, Part 2.
Topics: Adenosine Monophosphate; Alanine; Amisulpride; Carbamates; Cefiderocol; Cephalosporins; Chlorophenols; COVID-19 Drug Treatment; Drug Approval; Drug Combinations; Fumarates; Humans; Indans; Organophosphates; Oxadiazoles; Piperazines; Spiro Compounds; Tetrazoles; Thiophenes; Tromethamine; United States; United States Food and Drug Administration | 2021 |
Design, Synthesis and Molecular Docking Study of Novel 3-Phenyl-β-Alanine-Based Oxadiazole Analogues as Potent Carbonic Anhydrase II Inhibitors.
Topics: Alanine; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Catalytic Domain; Drug Design; Humans; Molecular Docking Simulation; Oxadiazoles | 2022 |
Multistep Synthesis of Analogues of Remdesivir: Incorporating Heterocycles at the C-1' Position.
Topics: Adenosine Monophosphate; Alanine; Nucleotides; Oxadiazoles | 2023 |