alanine has been researched along with opc 12759 in 425 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (1.18) | 18.7374 |
| 1990's | 62 (14.59) | 18.2507 |
| 2000's | 138 (32.47) | 29.6817 |
| 2010's | 187 (44.00) | 24.3611 |
| 2020's | 33 (7.76) | 2.80 |
| Authors | Studies |
|---|---|
| Hobara, T; Ishiyama, H; Izumi, Y; Kobayashi, H; Ogino, K; Oka, S; Yamasaki, K | 1 |
| Fujimura, J; Haruma, K; Kajiyama, G; Kishimoto, S; Kobayashi, H; Machino, H; Sakurai, K; Shimamoto, T; Shimizu, S; Yamasaki, K | 1 |
| Hotta, K; Ishihara, K; Komuro, Y; Nishiyama, N; Yamasaki, K | 1 |
| Imaizumi, T; Kamada, T; Kawano, S; Komemushi, S; Sato, N; Yamasaki, K | 1 |
| Hobara, T; Iida, Y; Ogino, K; Oka, S; Okazaki, Y; Takemoto, T; Yoshimura, S | 1 |
| Kanbe, T; Morita, S; Otsubo, K; Shimizu, T; Uchida, M; Yamasaki, K | 1 |
| Imaizumi, T; Ishiyama, H; Kanbe, T; Yabuuchi, Y; Yamasaki, K | 1 |
| Shimizu, T; Shioya, Y | 1 |
| Asada, S; Hirata, I; Ishiyama, H; Kanbe, T; Ooshiba, S; Shiraki, M; Yabuuchi, Y; Yamasaki, K | 1 |
| Chijiwa, T; Ishiyama, H; Kanbe, T; Morita, S; Yamasaki, K | 1 |
| Kanbe, T; Komatsu, M; Morita, S; Nakagawa, K; Tabusa, F; Uchida, M | 1 |
| Hong, KW; Kim, CD | 2 |
| Arakawa, T; Fukuda, T; Kobayashi, K; Watanabe, T; Yamasaki, K | 1 |
| Kitahora, T; Kitajima, M; Kubota, T; Kumai, K; Ono, H; Otani, Y; Shimazu, M; Tashiro, H; Wakabayashi, G; Yoshida, M | 1 |
| Kondo, M; Naito, Y; Sakurai, K; Tanigawa, T; Uchida, M; Yamasaki, K; Yoshikawa, T | 1 |
| Fukumura, D; Kai, A; Miura, S; Mori, M; Suematsu, M; Suzuki, H; Suzuki, M; Tsuchiya, M | 1 |
| Sakurai, K; Yamasaki, K | 1 |
| Iinuma, S; Kaneko, T; Kondo, M; Naito, Y; Nakamura, S; Nishimura, S; Takahashi, S; Yamasaki, K; Yoshikawa, T | 1 |
| Kondo, M; Naito, Y; Tanigawa, T; Yoshikawa, T | 1 |
| Kleine, A; Kluge, S; Peskar, BM | 1 |
| Arai, M; Iinuma, S; Kondo, M; Miyajima, T; Mukai, F; Naito, Y; Nakamura, Y; Sakamoto, K; Takenaka, S; Yagi, N; Yoshida, N; Yoshikawa, T | 1 |
| Huh, K; Lee, SH; Shin, US | 1 |
| Kim, KH; Lee, SM | 1 |
| Hirao, Y; Iinuma, S; Kondo, M; Miyazaki, R; Naito, Y; Osumi, T; Yagi, N; Yoshida, N; Yoshikawa, T | 1 |
| Chung, MH; Han, BG; Han, HS; Kim, HS; Rhee, KH | 1 |
| Goto, S; Hara, K; Kondo, T; Makiyama, K; Murase, K; Sekine, I; Urata, Y; Zea-Iriarte, WL | 1 |
| Kim, BK; Kim, HK; Kim, WB; Son, M; Yang, J | 1 |
| Hirose, M; Iwazaki, R; Kitamura, T; Miwa, H; Miyazaki, A; Oide, H; Sato, N; Wang, XE; Watanabe, S; Yoshizawa, T | 1 |
| Cho, SW; Hahm, KB; Kim, JH; Kim, YS; Lee, SI; Park, IS; Youn, JK | 1 |
| Harada, N; Johno, M; Murakami, K; Okabe, H; Okajima, K; Takatsuki, K; Uchiba, M | 1 |
| Ha, H; Kim, KH; Lee, SH | 1 |
| Antoku, S; Aramaki, R; Kusumoto, N; Tanaka, H | 1 |
| Ichikawa, H; Kokura, S; Kondo, M; Naito, Y; Takahashi, S; Takano, H; Tomii, T; Yoshida, N; Yoshikawa, T | 1 |
| Cho, SW; Hahm, KB; Joo, HJ; Kim, JH; Kim, YS; Lee, KJ; Yim, H | 2 |
| Aihara, M; Amano, K; Asaka, M; Fujii, N; Hayashi, S; Hirai, Y; Isogai, E; Isogai, H; Kikuchi, M; Oguma, K; Sugiyama, T; Yokota, K | 1 |
| Arakawa, T; Kobayashi, K; Tarnawski, A; Yoshikawa, T | 1 |
| Kondo, M; Naito, Y; Yoshida, N; Yoshikawa, T | 1 |
| Iinuma, S; Kondo, M; Naito, Y; Takahashi, S; Takemura, T; Yoshida, N; Yoshikawa, T | 1 |
| Cho, SW; Chung, MH; Hahm, KB; Kim, JH; Lee, KJ | 1 |
| Arakawa, T; Fujiwara, Y; Fukuda, T; Higuchi, K; Kobayashi, K; Kuroki, T; Takaishi, O; Tominaga, K; Uchida, T; Watanabe, T; Yamasaki, K | 1 |
| Boku, Y; Fujii, T; Iinuma, S; Kondo, M; Matsuyama, K; Naito, Y; Sasaki, E; Yagi, N; Yoshida, N; Yoshikawa, T | 1 |
| Arakawa, T; Kobayashi, K; Tarnawski, A | 1 |
| Ando, K; Arakawa, T; Fujiwara, Y; Fukuda, T; Higuchi, K; Kobayashi, K; Kuroki, T; Nebiki, H; Takaishi, O; Uchida, T; Yamasaki, K | 1 |
| Hirose, M; Osada, T; Sato, N; Tanaka, H; Wang, XE; Watanabe, S | 1 |
| Ikai, M; Itoh, M; Joh, T; Kurokawa, T; Seno, K; Yokoyama, Y | 1 |
| Azuma, A; Imagawa, K; Kikuchi, M; Nagano, C; Wakebe, H | 1 |
| Osaka, T; Sakurai, K; Yamasaki, K | 2 |
| Harada, N; Isobe, H; Murakami, K; Okabe, H; Okajima, K | 1 |
| Iwai, A; Iwashita, E | 1 |
| Ishii, H; Ishikawa, H; Kitahora, T; Kitajima, M; Miura, S; Otani, Y; Shimazu, M; Wakabayashi, G; Yoshida, M | 1 |
| Hong, KW; Kim, CD; Kim, KE; Lee, WS; Rhim, BY | 1 |
| Aihara, M; Funakoshi, Y; Imagawa, K; Kikuchi, M; Ohmoto, Y | 1 |
| Danielsson, D; Jurstrand, M | 1 |
| Aihara, M; Azuma, A; Funakoshi, Y; Imagawa, K; Kikuchi, M; Matsushima, K; Mukaida, N; Ohmoto, Y; Shindo, Y; Takizawa, H; Tsuchimoto, D | 1 |
| Ishii, H; Kai, A; Miura, S; Mori, M; Suematsu, M; Suzuki, H; Suzuki, M | 1 |
| Asaka, M; Hokari, K; Kagaya, H; Katagiri, M; Kato, M; Kudo, M; Nishikawa, K; Sato, F; Sugiyama, T; Sukegawa, M; Takeda, H | 1 |
| Ando, K; Arakawa, T; Harihara, S; Higuchi, K; Ito, H; Kobayashi, K; Kuroki, T; Nebiki, H; Uchida, T | 1 |
| Iwata, Y; Kikuoka, N; Matsumoto, H; Nakatani, H; Takahashi, T; Yamane, T | 1 |
| Ahn, BW; Cha, SH; Chay, KO; Jung, YD; Lee, MW; Ryu, MH; Song, DU; Yang, SY | 1 |
| Hong, KW; Kim, CD; Kim, HH | 1 |
| Huh, K; Kim, JS; Kim, SK; Kwon, TH; Shin, US | 1 |
| Fitzpatrick, LR; Le, T; Sakurai, K | 1 |
| Arakawa, T; Higuchi, K; Kobayashi, K; Kuroki, T; Takaishi, O; Yamasaki, K | 1 |
| Hirakata, R; Migita, S; Miyake, K; Nomura, H; Okamoto, O; Shiraishi, G | 1 |
| Hirasaki, S; Koide, N; Ogawa, H; Tsuji, T | 1 |
| Ahn, W; Case, RM; Kim, H; Kim, KH; Lee, MG; Lee, SI; Moon, SJ; Seo, JT | 1 |
| Kim, H; Kim, KH; Seo, JY | 1 |
| Al-Sohaibani, MO; Najjar, TA; Saad, SY | 1 |
| Abely, M; de Mascarel, A; Heyman, M; Matysiak-Budnik, T; Mayo, K; Mégraud, F | 1 |
| Adachi, K; Fukuda, R; Ishihara, S; Kazumori, H; Kinoshita, Y; Moriyama, N; Suetsugu, H; Watanabe, M | 1 |
| Kawasaki, H; Makiyama, K; Takeshima, F; Zea-Iriarte, WL | 1 |
| Hong, KW; Kim, CD; Kim, YK; Lee, SH | 1 |
| Asaka, M; Hayashi, S; Hirai, Y; Isogai, E; Isogai, H; Oguma, K; Shimomura, H; Sugiyama, T; Yokota, K | 1 |
| Garcia del Saz, E; Jiang, F; Kataoka, S; Kobayashi, T; Okada, T; Seguchi, H; Tsunawaki, S; Yamasaki, Y; Zinchuk, VS | 1 |
| Haruma, K; Kishimoto, S; Nakagawa, Y; Nakano, M; Sakurai, K; Tari, A | 1 |
| Gunawan, ES; Hori, M; Iijima, H; Kakiuchi, Y; Kawai, N; Kawano, S; Kimura, A; Okuda, Y; Sasaki, Y; Sun, WH; Tsuji, S; Tsujii, M; Yasumaru, M | 1 |
| Banan, A; Fitzpatrick, L; Keshavarzian, A; Zhang, Y | 1 |
| Asaka, M; Kashiwagi, S; Miyake, K; Nomura, H; Sugiyama, T | 1 |
| Azuma, A; Imagawa, K; Ishiyama, H; Kikuchi, M; Nagano, C; Sekiguchi, K | 1 |
| Choi , JM; Hong , KW; Shin , YW | 1 |
| Masamune, A; Sakai, Y; Shimosegawa, T; Yoshida, M | 1 |
| Heyman, M; Matysiak-Budnik, T; Mégraud, F; Thomas-Collignon, A | 1 |
| Marcuard, SP; Riff, DS; Schwartz, H; Talley, NJ | 1 |
| Chung, MH; Hong, WS; Jung, HY; Kim, HW; Kim, JH; Lee, HS; Min, YI; Myung, SJ; Yang, SK | 1 |
| Kim, JY; Kim, KH; Ro, JY | 1 |
| Kanatsu, K; Kato, S; Mizoguchi, H; Ogawa, Y; Takeuchi, K; Tanaka, A | 1 |
| Fujishita, T; Nakajima, K; Okabe, S; Tsukimi, Y | 1 |
| Inaba, T; Kawai, K; Kita, K; Mizuno, M; Okada, H; Takaguchi, K; Tsuji, T; Yoshida, Y | 1 |
| Choi, KW; Choi, MG; Chung, IS; Chung, MH; Hahm, KB; Hong, WS; Jung, HY; Kim, JG; Kim, JH; Kim, NY; Kim, SW; Lee, JJ; Lee, SW; Lee, YC; Roe, IH | 1 |
| Arakawa, M; Fujimori, K; Gejyo, F; Mochizuki, H; Suzuki, E | 1 |
| Fukuda, S; Liu, Q; Shimoyama, T; Sugawara, K | 1 |
| Chayama, K; Haruma, K; Ito, M; Kido, S; Kitadai, Y; Manabe, N; Sumii, M; Tanaka, S; Yoshihara, M | 1 |
| Banan, A; Farhadi, A; Fitzpatrick, LR; Keshavarzian, A; Mutlu, E; Zhang, Y | 1 |
| Akamatsu, T; Furuya, N; Gotou, A; Hirao, Y; Katsuyama, T; Kiyosawa, K; Miyamoto, G; Nakamura, N; Osumi, T; Shimizu, T | 1 |
| Arakawa, T; Fujiwara, Y; Hamaguchi, M; Higuchi, K; Tanigawa, T; Tominaga, K; Wada, R; Watanabe, T | 1 |
| Koyama, N; Miyamoto, G; Sasabe, H | 1 |
| Adachi, K; Fujishiro, H; Kinoshita, Y; Komazawa, Y; Mihara, T | 1 |
| Cho, SW; Hahm, KB; Han, SU; Kim, DY; Kim, JH; Kim, MW; Kim, YB; Lee, JS; Nahm, KT; Oh, TY; Song, YJ; Surh, YJ; Yoo, BM | 1 |
| Hirohata, S; Inaba, G; Kogure, M; Matsuda, T; Miyanaga, Y; Mizushima, Y; Nakamura, S; Ohno, S; Tanaka, S; Ujihara, H | 1 |
| Higaki, K; Kimura, T; Minami, T; Miyake, M; Odomi, M; Ogawara, K; Oka, Y; Toguchi, H | 1 |
| Ichiba, M; Murawaki, Y; Shiota, G; Udagawa, A | 1 |
| Fukuda, S; Fukuda, Y; Liu, Q; Nakaji, S; Shimoyama, T; Sugawara, K | 1 |
| Kaidzu, S; Ohira, A; Takanashi, T; Tanito, M; Yoshida, Y | 1 |
| Arakawa, T; Fujiwara, Y; Hamaguchi, M; Higuchi, K; Matsumoto, T; Oshitani, N; Sasaki, E; Shiba, M; Takashima, T; Tanigawa, T; Tominaga, K; Watanabe, T | 1 |
| Genta, RM | 1 |
| Cho, SW; Cho, YK; Hahm, KB; Joo, HJ; Kim, DH; Kim, JH; Kim, YB; Lee, JS; Lee, KM; Nam, KT; Surh, YJ; Yoo, BM | 1 |
| Jung, HC; Kim, JM; Kim, JS; Song, IS | 1 |
| Heyman, M; Matysiak-Budnik, T; Mégraud, F | 1 |
| Hanashiro, K; Ichiishi, E; Ichikawa, H; Ishikawa, T; Kokura, S; Kuchide, M; Naito, Y; Okanoue, T; Uchiyama, K; Yamamura, Y; Yoshida, N; Yoshida, Y; Yoshikawa, T | 1 |
| Akiba, Y; Ishii, H; Matsui, H; Nakamura, M; Tsuchimoto, K | 2 |
| Chayama, K; Haruma, K; Ito, M; Kamada, T; Kim, S; Kitadai, Y; Kuwai, T; Matsutani, N; Sumii, M; Tanaka, S; Yoshihara, M | 1 |
| Ishihara, S; Kadowaki, Y; Kazumori, H; Kinoshita, Y; Miyaoka, Y; Ortega-Cava Cesar, F; Rumi, M; Wada, T; Yoshino, N; Yuki, M; Yuki, T | 1 |
| Bamba, H; Fujiwara, K; Kato, A; Kawamoto, C; Miyatani, H; Ota, S; Yoshida, Y | 1 |
| Kataoka, S; Kuwayama, H; Soma, R; Takada, H; Takagi, K; Takahashi, M | 1 |
| Alexander, JS; Itoh, M; Joh, T; Nomura, T; Ohara, H; Oshima, T; Sasaki, M; Seno, K; Takezono, Y; Yokoyama, Y | 1 |
| Amemori, S; Fujimoto, K; Fujise, T; Iwakiri, R; Kojima, M; Lin, T; Oguzu, T; Ootani, A; Sakata, H; Shimoda, R; Tsunada, S; Watanabe, K; Wu, B | 1 |
| Arakawa, T; Asaka, M; Fujioka, T; Ishii, H; Itoh, M; Kawai, S; Kobayashi, K; Kuwayama, H; Sato, R; Shimoyama, T; Takemoto, T; Yoshikawa, T | 1 |
| Haruma, K; Ito, M | 1 |
| Bevilacqua, C; Gaboriau-Routhiau, V; Heyman, M; Matysiak-Budnik, T; Mayo, K; Mégraud, F; Moreau, MC; van Niel, G | 1 |
| Lee, KM; Park, HJ; Park, NC; Shin, DG | 1 |
| Anniko, M; Ohtani, M; Takumida, M | 1 |
| Inoue, K; Kuramoto, M; Ogawa, M; Shimada, S; Suzuki, S; Yamamoto, K | 1 |
| Chai, J; Chiou, SK; Pai, R; Tarnawski, AS | 1 |
| Choue, R; Hahm, KB; Jin, JH; Oh, TY; Park, S | 1 |
| Fujisawa, S; Okamoto, T; Shinohara, H; Takeji, Y; Urashima, H | 2 |
| Koga, T; Konishi, T; Sakurai, K; Sasabe, H | 1 |
| Higaki, K; Kamada, N; Kimura, T; Minami, T; Miyake, M; Mukai, T; Odomi, M; Ogawara, K; Oka, Y; Toguchi, H | 1 |
| Han, HS; Jun, YS; Kim, CH; Lee, KC; Rho, JI; Shin, BS; Yoo, SD; Yoon, CH | 1 |
| Ahn, W; An, JM; Kim, J; Kim, KH; Lee, SI; Moon, SJ; Seo, JT | 1 |
| Kato, S; Nishio, H; Okayama, M; Takeuchi, K; Tsubouchi, R | 1 |
| Furuta, R; Goto, H; Kusugami, K | 1 |
| Chai, J; Chiou, SK; Chu, EC; Pai, R; Tarnawski, A | 1 |
| Hur, GY; In, KH; Jung, HC; Jung, KH; Kang, EJ; Kang, KH; Kim, JH; Lee, SY; Shim, JJ; Shin, C; Yoo, SH | 1 |
| Fujimori, S; Futagami, S; Gudis, K; Hiratsuka, T; Kusunoki, M; Miyake, K; Nishigaki, H; Sakamoto, C; Shinji, Y; Shinoki, K; Suzuki, K; Tatsuguchi, A; Tsukui, T; Wada, K | 1 |
| Handa, O; Ichikawa, H; Kajikawa, H; Katada, K; Kokura, S; Kuroda, M; Matsui, H; Mizushima, K; Naito, Y; Shimozawa, M; Takagi, T; Yoshida, N; Yoshikawa, T | 1 |
| Atsuda, K; Hibi, N; Matsui, H; Matsumoto, T; Nakamura, M; Takahashi, T; Tsuchimoto, K; Yamada, H | 1 |
| Ishikawa, T; Kakumu, S; Kasugai, K; Miyata, M; Mori, T; Onishi, M | 1 |
| Kumakura, T; Maeda, T; Mori, T; Nagamoto, H; Nakashima, T; Takai, M | 1 |
| Arakawa, T; Fujiwara, Y; Higuchi, K; Oshitani, N; Sasaki, E; Tarnawski, AS; Tominaga, K; Watanabe, T; Yoshikawa, T | 1 |
| Harada, N; Liu, W; Okajima, K | 1 |
| Arakawa, T; Fujiwara, Y; Higuchi, K; Oshitani, N; Sasaki, E; Shiba, M; Taira, K; Tominaga, K; Watanabe, T | 1 |
| Asahi, K; Eguchi, H; Fu, HY; Hayashi, N; Kawano, S; Murata, H; Tsuji, S; Tsujii, M; Yabe, Y | 1 |
| Matsui, H; Matsuzaki, Y; Muramatsu, M; Nagano, Y; Nakahara, A; Nakamura, Y; Shibahara, T; Shimokawa, O; Tanaka, N; Yanaka, A | 1 |
| Futagami, S; Gudis, K; Hamamoto, T; Hiratsuka, T; Kusunoki, M; Miyake, K; Sakamoto, C; Shindo, T; Shinji, Y; Shinoki, K; Suzuki, K; Tsukui, T; Ueki, N; Wada, K | 1 |
| Ichikawa, H; Isozaki, Y; Katada, K; Naito, Y; Okanoue, T; Tomatsuri, N; Yoshida, N; Yoshikawa, T | 1 |
| Anniko, M; Takumida, M | 2 |
| Arakawa, T; Fujiwara, Y; Higuchi, K; Tominaga, K; Watanabe, T | 1 |
| Higaki, K; Hirota, M; Kimura, T; Minami, T; Miyake, M; Odomi, M; Ogawara, K; Toguchi, H | 1 |
| Higaki, K; Kamada, N; Kato, Y; Kimura, T; Minami, T; Miyake, M; Mukai, T; Odomi, M; Ogawara, K; Oka, Y; Toguchi, H; Yamazaki, H | 1 |
| Kakumu, S; Konagaya, T; Miyata, M; Mori, T | 1 |
| Arakawa, T; Asaka, M; Fujioka, T; Haruma, K; Ishii, H; Kinoshita, Y; Kobayashi, K; Sakaki, N; Sakamoto, C; Shimosegawa, T; Sugiyama, T; Takahashi, S; Terano, A; Yoshikawa, T | 1 |
| Dartt, DA; Ríos, JD; Shatos, M; Tran, H; Urashima, H | 1 |
| Fujimura, M; Ishiura, Y; Myou, S; Nakao, S; Nobata, K | 1 |
| Choi, JM; Hong, KW; Kim, CD | 1 |
| Higaki, K; Kimura, T; Minami, T; Miyake, M; Odomi, M; Ogawara, K; Toguchi, H | 1 |
| Hojo, M; Hori, K; Matsumoto, T; Miwa, H; Nagahara, A; Ohkusa, T; Osada, T; Sato, N; Tomita, T | 1 |
| Kajihara, H; Usijima, S; Yoshinaga, T | 1 |
| Arakawa, T; Pai, R; Tanigawa, T; Tarnawski, AS | 1 |
| Asencio, C; Candalh, C; Heyman, M; Laharie, D; Matysiak-Budnik, T; Mégraud, F; Ménard, S; Rullier, A; Vidal-Martinez, T; Zerbib, F | 1 |
| Naito, Y; Yoshikawa, T | 2 |
| Goto, H; Hirooka, Y; Itoh, A; Nakamura, M; Niwa, Y; Omiya, N | 1 |
| Akiyama, K; Ann, T; Fukui, H; Haruma, K; Kikuchi, E; Kinoshita, Y; Kojima, H; Matsumoto, M; Mitoro, A; Miyauchi, Y; Nakayama, M; Ono, H; Sakurai, G; Takakura, Y; Yajima, H; Yamao, J; Yoshida, M; Yoshikawa, M | 1 |
| Ando, T; Furuta, R; Goto, H; Ina, K; Ishiguro, K; Kusugami, K; Maeda, O; Watanabe, O | 1 |
| Hagiwara, T; Hattori, T; Ling, ZQ; Mukaisho, K; Sakano, T; Sugihara, H | 1 |
| Choi, KY; Chung, IS; Han, JY; Kim, HK; Kim, JI; Kim, JK; Park, SH | 1 |
| Hashiguchi, K; Hoshikawa, Y; Kanbe, T; Kurimasa, A; Mukoyama, T; Murai, R; Shimomura, T; Shiota, G; Tsuchiya, H; Yoshida, Y | 1 |
| Fukui, H; Takakura, Y; Yajima, H; Yamao, J | 1 |
| Arakawa, T; Haruma, K; Higuchi, K; Joh, T; Kobayashi, K; Murakami, K; Sugiyama, T; Suzuki, H; Terano, A; Yoshikawa, T | 1 |
| Hamada, Y; Ito, S; Kamiyama, Y; Matsui, K; Nishizawa, M; Okumura, T; Ozaki, T; Tanaka, H; Tokuhara, K; Yamada, M | 1 |
| Aihara, E; Amagase, K; Hayashi, S; Kato, S; Takeuchi, K | 1 |
| Arakawa, T; Sugimori, S; Watanabe, T | 1 |
| Arakaki, R; Hayashi, Y; Ishimaru, N; Kohashi, M | 1 |
| Chen, J; Du, Y; Fang, D; Gao, J; Gong, Y; Guo, X; He, L; Jiang, B; Li, Y; Li, Z; Ren, J; Shi, R; Tian, Z; Wu, J; Zhan, X; Zhang, Z | 1 |
| Dartt, DA; Ríos, JD; Shatos, MA; Urashima, H | 1 |
| Cho, M; Heo, J; Kang, DH; Kim, GH; Kim, TO; Lee, SM; Song, GA | 1 |
| Handa, O; Ichikawa, H; Isozaki, Y; Kajikawa, H; Kokura, S; Matsui, H; Naito, Y; Nakabe, N; Suzuki, T; Takagi, T; Yoshida, N; Yoshikawa, T | 1 |
| Fuchikami, J; Takahashi, M; Takeuchi, Y | 1 |
| Chitapanarux, T; Lertprasertsuke, N; Praisontarangkul, OA | 1 |
| Ando, T; Goto, H; Hirooka, Y; Itoh, A; Maeda, O; Nakamura, M; Niwa, Y; Ohmiya, N | 1 |
| Matsumoto, S; Shirahama, S; Tsuji, K | 1 |
| Kishimoto, N; Li, GF; Wang, CX; Yamamoto, A; Yan, Y | 1 |
| Chiba, H; Kaneko, T; Matsuo, A; Miyamatsu, H; Satomi, T; Yasuda, T | 1 |
| Akira, Y; Duan, L; Huang, BB; Li, GF; Luo, JH; Nobuaki, K | 1 |
| Kapoor, S | 2 |
| Hashimoto, K; Joh, T; Kim, Y; Matsumoto, T; Miwa, H; Oshima, T; Tomita, T | 1 |
| Kanamitsu, K; Kikuchi, A; Maeda, T; Odomi, M; Sasabe, H; Tamai, I; Tanaka, M; Tomoyasu, T | 1 |
| Akahoshi, T; Anegawa, G; Hashizume, M; Kawanaka, H; Kinjo, N; Konishi, K; Maehara, Y; Tanoue, K; Tarnawski, A; Tomikawa, M; Yamaguchi, S; Yoshida, D | 1 |
| Bang, D; Choi, B; Kwon, HJ; Lee, ES; Lee, S; Sohn, S | 1 |
| Higaki, K; Kimura, T; Miyake, M; Mukaizawa, F; Odomi, M; Ogawara, K; Taniguchi, K | 1 |
| Ichikawa, T; Iijima, K; Koike, T; Ogawa, M; Ohara, S; Okada, S; Shimosegawa, T | 1 |
| Haixia, C; Jie, L; Qi, Z; Xiaoying, Z | 1 |
| Kawakami, A; Koni, I; Nishinarita, M; Nishiyama, S; Ohta, S; Oka, H; Sawada, S; Sugai, S; Sugiyama, E; Takahashi, H; Takei, M; Umehara, H; Yamaji, K | 1 |
| Andreadou, I; Kostakis, IK; Marakos, P; Panteleon, V; Pouli, N | 1 |
| Hibi, T; Iwasaki, E; Masaoka, T; Minegishi, Y; Nakagawa, I; Nishizawa, T; Suzuki, H | 1 |
| Chen, X; Wen, X; Zhou, X | 1 |
| Goto, S; Kawai, T; Yamagishi, T | 1 |
| Chayanupatkul, M; Klaikeaw, N; Mahachai, V; Rerknimitr, R; Thong-Ngam, D | 1 |
| Aihara, E; Ohashi, Y; Takahashi, K; Takasuka, H; Takeuchi, K | 1 |
| Araki, H; Ibuka, T; Kato, T; Moriwaki, H; Nagaki, M; Onogi, F; Sugiyama, A; Tomita, E | 1 |
| Cho, HY; Lee, YB; Park, GK; Yoon, H | 1 |
| Ishihara, T; Mizushima, T; Tanaka, K; Tashiro, S; Yoshida, K | 1 |
| Ichikawa, H; Kamada, K; Suzuki, T; Takagi, T; Tomatsuri, N; Yoshida, N; Yoshikawa, T | 1 |
| Cheon, JH; Kim, JH; Kim, YJ; Lee, SK; Lee, YC | 1 |
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| Choe, JY; Kim, SK; Lee, SJ; Park, KY; Park, SH | 1 |
| Hong, KW; Kang, DW; Min, do S; Min, G; Park, DY | 1 |
| Ehara, A; Fujimori, S; Gudis, K; Kobayashi, T; Mitsui, K; Sakamoto, C; Seo, T; Takahashi, Y; Tanaka, S; Tatsuguchi, A; Yonezawa, M | 1 |
| Asaka, M; Kamada, G; Kato, M; Nishida, M; Nishida, U; Ono, S; Shimizu, Y; Yoshida, T | 1 |
| Azuma, T; Fujiwara, S; Itoh, T; Kawakami, F; Kutsumi, H; Morita, Y; Toyonaga, T; Yoshida, M | 1 |
| Amagase, K; Kato, S; Takeuchi, K | 1 |
| Bo, J; Chen, MH; Fan, DM; Ge, ZZ; Ji, F; Jung, HC; Kim, JH; Lee, SW; Lee, YC; Song, KH | 1 |
| Furuta, R; Hibi, S; Ina, K; Kabeya, M; Kataoka, T; Kato, T; Kawai, M; Kayukawa, S; Kikuchi, F; Minagawa, Y; Tajiri, C; Yuasa, S | 1 |
| Aoyagi, Y; Hashimoto, S; Kobayashi, M; Mizuno, K; Narisawa, R; Sato, Y; Takeuchi, M | 1 |
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| Hushimi, C; Inoue, T; Kamata, S; Kobayashi, M; Masubuchi, T; Miura, K; Moya, M; Tada, Y; Tajima, H; Tosaka, C | 1 |
| Ha, JM; Kim, JY; Oh, TO; Park, CW; Park, ES; Rhee, YS; Tung, NT | 1 |
| Abe, T; Fujioka, T; Inoue, K; Kodama, M; Mizukami, K; Murakami, K; Okimoto, T; Uchida, M | 1 |
| Fukuhara, K; Hayaishi, Y; Katsuragi, K; Kodama, S; Morisya, Y; Nakanishi, C; Terakura, M | 1 |
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| Abell, TL; Palmer, M; Tang, SJ; Tran, RT; Yang, J | 1 |
| Aoki, A; Shinohara, H; Takeji, Y; Urashima, H | 1 |
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| Chen, ML; Diao, L; Hu, J; Jin, J; Liu, XC; Mei, Q; Xu, JM; Yao, Q | 1 |
| Chi, SC; Ha, JM; Kim, JY; Oh, TO; Park, CW; Park, ES; Rhee, YS; Tung, NT | 1 |
| An, Y; Cheng, G; Gao, P; Ji, Z; Shi, Y; Zou, M | 1 |
| Hirayama, A; Hyodo, I; Indo, HP; Kaneko, T; Majima, HJ; Matsui, H; Nagano, Y; Nakamura, Y; Rai, K; Shimokawa, O; Tamura, M | 1 |
| Fujishiro, M; Ichinose, M; Inada, K; Kageyama-Yahara, N; Kato, J; Kodashima, S; Koike, K; Konno-Shimizu, M; Niimi, K; Oka, M; Ono, S; Tamai, H; Tsutsumi, Y; Yamamichi, N | 1 |
| Chin, YW; Chung, YH; Jung, K; Kim, J; Lee, B; Min, DS; Park, YH; Yoo, H | 1 |
| Cho, ML; Jeong, JH; Kim, EK; Kim, HY; Min, JK; Moon, SJ; Oh, HJ; Park, JS; Park, MK; Park, SH; Woo, YJ | 1 |
| Choi, KY; Ha, WS; Hwang, WC; Kang, DW; Kim, KS; Ko, GH; Lee, YC; Min, DS; Park, MH | 1 |
| Andoh, A; Fujimoto, T; Fujiyama, Y; Imaeda, H; Kasumi, E; Takahashi, K | 1 |
| Awamura, S; Kinoshita, S; Nakamichi, N; Oshiden, K; Suzuki, H; Yokoi, N | 3 |
| Fukumoto, K; Handa, O; Harusato, A; Horie, R; Ichikawa, H; Inoue, K; Mizushima, K; Naito, Y; Takagi, T; Uchiyama, K; Yagi, N; Yamada, S; Yoshikawa, T | 1 |
| Dou, J; Hu, X; Liu, J; Shen-Tu, J; Wu, G; Wu, L; Xu, Q; Zhou, H | 1 |
| Hasegawa, M; Horiki, N; Katsurahara, M; Sudo, A; Takei, Y; Tanaka, K; Tano, S; Uchida, A; Wakabayashi, H | 1 |
| Cho, ML; Jeong, JH; Kim, EK; Kim, HY; Min, JK; Moon, SJ; Park, JS; Park, MK; Park, SH; Yang, EJ | 1 |
| Arakawa, T; Fujiwara, Y; Nadatani, Y; Ohkawa, F; Otani, K; Shiba, M; Sogawa, M; Takeuchi, K; Tanigawa, T; Tominaga, K; Watanabe, K; Watanabe, T; Yamagami, H | 1 |
| Bai, Y; Chen, Q; Chen, Y; Mao, H; Qing, Q; Zhang, S; Zhang, Y; Zhu, W | 1 |
| Haruta, J; Kimura, K; Morita, Y; Orita, T; Sonoda, KH; Takeji, Y | 1 |
| Fujita, T; Kato, M; Katsuki, S; Kurokawa, S; Nishikawa, K; Ohira, K; Ohta, H; Saitoh, Y; Sato, Y; Yamada, M | 1 |
| Fukuda, K; Fukushima, A; Harada, Y; Ishida, W; Sumi, T; Tanaka, H | 1 |
| Kinoshita, S; Sotozono, C; Ueta, M; Yokoi, N | 1 |
| Inoue, Y; Koh, S; Maeda, N; Nishida, K; Sugmimoto, T | 1 |
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| Asakuma, Y; Kashida, H; Kawasaki, M; Kudo, M; Matsui, S; Sakurai, T; Takayama, M | 1 |
| Itoh, K; Itoh, S; Shinohara, H | 1 |
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| Amagase, K; Satoh, H; Takeuchi, K | 1 |
| Funahashi, Y; Gotoh, M; Majima, T; Takai, S; Yamamoto, T; Yoshida, M | 2 |
| Cooper, DL; Harirforoosh, S; Wood, RC; Wyatt, JE | 1 |
| Bullins, KW; Denham, JW; Hanley, AV; Hanley, GA; Harirforoosh, S; Panus, PC; Wood, RC; Wyatt, JE | 1 |
| Ichinose, A; Kakizaki, H; Takahashi, Y | 1 |
| Kinoshita, S; Koga, A; Sotozono, C; Ueta, M; Yokoi, N | 1 |
| Dogru, M; Ishida, R; Kaido, M; Tsubota, K | 1 |
| Fukui, H; Hida, N; Hori, K; Miwa, H; Nakamura, S; Ogawa, T; Ohda, Y; Okugawa, T; Oshima, T; Tomita, T; Tozawa, K; Watari, J | 1 |
| Ishida, T; Matsuda, T; Nakashima, T; Sako, N; Sakurai, K; Uematsu, N | 1 |
| Furuta, T; Sugimoto, M; Uotani, T | 1 |
| Byun, JK; Cho, ML; Jhun, JY; Kim, EK; Kim, HY; Min, JK; Moon, SJ; Park, JS; Park, SH; Youn, J | 1 |
| Cho, ML; Jeong, JH; Kim, EK; Kim, HY; Kim, SM; Lee, HJ; Lee, SY; Lee, WS; Lim, MA; Min, JK; Moon, SJ; Park, JS; Park, SH; Woo, YJ | 1 |
| Arakaki, R; Eguchi, H; Enkhmaa, T; Hayashi, Y; Hotta, F; Ishimaru, N; Iwasa, A; Kudo, Y; Mitamura, Y; Mitamura-Aizawa, S; Yamada, A | 1 |
| Choi, HG; Choi, IS; Choi, JY; Kim, JO; Pradhan, R; Tran, TH; Yong, CS | 1 |
| Cao, Z; Dong, W; Guo, X; Liu, M; Song, J; Wang, J; Ye, C; Yu, S; Zhang, J | 1 |
| Hossain, MA; Ikeda, Y; Nagasaki, Y; Vong, LB; Yamashita, M | 1 |
| Arimoto, A; Kitagawa, K; Mita, N; Sasaki, H; Shibuya, E; Takahashi, Y | 1 |
| Cho, CS; Kang, YM; Kim, JH; Kim, SK; Lee, DH; Lee, SK; Lee, ST; Lee, YC; Park, SH; Park, W; Park, YW; Rew, JS; Yoo, WH | 1 |
| Azuma, T; Higuchi, K; Iguchi, M; Machida, H; Morita, Y; Naito, Y; Takeuchi, T; Takeuchi, Y; Tamada, T; Tominaga, K; Uedo, N; Yagi, N; Yamao, J; Yazumi, S | 1 |
| Kase, M; Kase, S; Shinohara, T | 1 |
| Fukuda, K; Fukushima, A; Harada, Y; Ishida, W; Tanaka, H | 1 |
| Chen, D; Lai, S; Li, Q; Liu, L; Ma, X; Wang, T; Wei, Y; Xiong, J; Yang, Y; Zhang, P | 1 |
| Brocklehurst, P; Glenny, AM; Gorodkin, R; Pemberton, MN; Riley, P; Taylor, J; Walsh, T | 1 |
| Chang, H; Choi, YJ; Kang, KK; Kim, HJ; Kim, N; Lee, DH; Lee, HS; Lee, JY; Nam, RH; Seo, JH | 1 |
| Abe, M; Bamba, N; Enami, A; Makihara, K; Masaoka, M; Masuda, N; Mizutani, M; Shikata, A; Takada, S; Yamamoto, M; Yamamura, J; Yasojima, H | 1 |
| Kanai, T; Nishizawa, T; Nishizawa, Y; Suzuki, H; Takahashi, M; Yahagi, N | 1 |
| Amagase, K; Hashimoto, E; Itayama, M; Izuhara, C; Takayama, S; Takeuchi, K | 1 |
| Ebi, M; Hayashi, N; Joh, T; Katano, T; Kataoka, H; Mizoshita, T; Mori, Y; Ozeki, K; Shimura, T; Tanida, S; Tatematsu, M; Tsukamoto, H; Tsukamoto, T | 1 |
| Han, SH; Kim, HJ; Kim, JH; Lee, JH; Moon, W; Park, J; Park, SJ; Song, GA | 1 |
| Choi, WS; Lee, GR; Lee, SE; Oh, S; Son, DJ | 1 |
| Fukui, M; Kamoi, M; Kawakita, T; Mukai, S; Ogawa, Y; Saijo-Ban, Y; Simmura, S; Tsubota, K; Yaguchi, S; Yamane, M | 1 |
| Gao, P; Li, R; Li, W; Liang, K; Ma, W; Wang, Y; Xu, X; Zhao, Y | 1 |
| Arakawa, T; Fujiwara, Y; Kohata, Y; Nakahara, K; Shiba, M; Tanigawa, T; Tominaga, K; Watanabe, T; Yamagami, H | 1 |
| Arakawa, T; Fujimoto, K; Handa, O; Higuchi, K; Naito, Y; Sakata, Y; Shiba, M; Takeuchi, T; Tanigawa, T; Watanabe, T; Yoshikawa, T | 1 |
| Igarashi, A; Kamiya, K; Kobashi, H; Shimizu, K | 1 |
| Engqvist, H; Karlsson Ott, M; Pujari-Palmer, M; Pujari-Palmer, S | 1 |
| Maeda, Y; Matsumiya, W; Nagai, T; Nakamura, M; Otsuka, K; Ueda, K | 1 |
| Akiyama, T; Haruma, K; Hata, J; Inoue, K; Ito, M; Kamada, T; Manabe, N; Matsumoto, H; Murao, T; Sato, M; Shiotani, A; Tanaka, S; Tokutomi, T; Watanabe, T | 1 |
| Chen, QK; Lai, Y; Li, JY; Ouyang, H; Shan, TD; Xia, ZS; Yang, HS; Yu, T; Zhong, W | 1 |
| Cho, KM; Choi, SK; Chung, JO; Jun, CH; Kim, BS; Kim, HS; Kim, TJ; Park, CH; Park, SY; Rew, JS; Son, DJ | 1 |
| Nakamura, K; Nakamura, M; Onikubo, T; Shinohara, A | 1 |
| Nakashima, T; Sakurai, K; Sasabe, H; Sato, A; Sato, M; Shibamori, M; Uematsu, N; Umehara, K; Yamamura, Y | 1 |
| Chen, X; Han, X; Jiang, K; Li, S; Wang, B; Zhou, L | 1 |
| Uno, M | 1 |
| Denham, JW; Harirforoosh, S; Murrell, DE; Panus, PC; Rahmasari, Y | 1 |
| Choe, JY; Kim, SK; Park, KY | 1 |
| Eguchi, E; Kubo, M; Murakami, I; Nagaoka, K; Ogino, K; Zhang, R | 1 |
| Ikeda, T; Mimura, M; Oku, H; Sato, B; Ueki, M | 1 |
| Feily, A; Nilforoushzadeh, MA; Rasaii, S | 1 |
| Fujimoto, C; Fujita, M; Igarashi, T; Kobayashi, M; Nakano, Y; Suzuki, H; Takahashi, H; Yamada, Y | 1 |
| Imaoka, F; Katayama, S; Kizu, J; Kuroda, Y; Matsumoto, K; Wako, T; Yajima, R | 1 |
| Hirano, K; Kato, K; Kondo, M; Matsubara, H; Matsunaga, K; Sugimoto, M; Takashima, Y | 1 |
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| Simanenkov, VI; Tikhonov, SV | 1 |
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| Hutami, IR; Iwasa, A; Izawa, T; Mino-Oka, A; Mori, H; Shinohara, T; Tanaka, E | 1 |
| Carvalhaes, A; De Nucci, G; Gagliano-Jucá, T; Magalhães, AF; Moreno, RA; Napolitano, M; Trevisan, MS; Wallace, JL; Zaminelli, T | 1 |
| Choi, KY; Hwang, WC; Kang, DW; Min, do S; Noh, YN | 1 |
| Akahoshi, K; Akiho, H; Aso, A; Harada, N; Iboshi, Y; Ihara, E; Iwasa, T; Nakamura, K; Nakamura, N; Ochiai, T; Ogino, H; Takayanagi, R | 1 |
| Dy, F; Hong, SJ; Hwangbo, Y; Jang, JY; Kim, JG; Kim, JJ; Lee, DH; Lee, HL; Lee, SW; Lee, YC; Leelakusolvong, S; Liu, F; Moon, JS; Park, SH; Shin, WG; Wang, B; Xu, J; Xue, Z; Yuan, Y | 1 |
| Cho, ML; Kim, EK; Kim, JK; Kwok, SK; Lee, J; Lee, SH; Lee, SY; Min, HK; Park, SH | 1 |
| Ito, Y; Nagai, N; Okamoto, N; Shimomura, Y | 1 |
| Ding, J; Kam, WR; Liu, Y; Sullivan, DA | 1 |
| Miyake, M; Nakai, D | 1 |
| Li, H; Li, S; Tang, P; Xiao, Y; Xiong, X; Xu, K | 1 |
| Argüeso, P; Uchino, Y; Woodward, AM | 1 |
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| Jeong, S; Jung, Y; Kim, BJ; Kim, D; Kim, W; Lee, S; Min, DS; Yang, Y; Yoon, JH | 1 |
| Arakawa, T; Fujiwara, Y; Kamata, N; Nadatani, Y; Nagami, Y; Otani, K; Shiba, M; Shimada, S; Tanaka, F; Tanigawa, T; Tominaga, K; Watanabe, T; Yamagami, H | 1 |
| Kawaguchi, M; Ogane, M; Okubo, M; Shinomiya, T; Tsukagoshi, E; Yoshikawa, M | 1 |
| Haraguchi, T; Kojima, H; Li, D; Nakamura, S; Shiraishi, S; Uchida, T; Yoshida, M | 1 |
| Hiratsuka, Y; Kawashima, M; Shigeyasu, C; Suwaki, K; Tsubota, K; Uchino, M; Yamada, M; Yokoi, N | 1 |
| Nakashima, T; Sakurai, K; Uematsu, N | 1 |
| Cho, ML; Jeong, JH; Jhun, J; Jung, K; Kim, EK; Kim, SY; Kwon, JE; Lee, SH; Min, JK; Na, HS | 1 |
| Cho, HY; Lee, YB; Ngo, L; Tran, P; Yoo, HD | 1 |
| Abdallah, DM; El-Abhar, HS; Gendy, AM | 1 |
| Hiraoka, S; Ishida, T; Matsuda, T; Ogura, A; Urashima, H | 1 |
| Beppu, T; Fujii, M; Fujii, T; Fujimoto, Y; Hasegawa, Y; Hirano, S; Iwae, S; Kojima, H; Matsushima, Y; Matsuura, K; Monden, N; Naka, Y; Nishimori, H; Ogawa, T; Okami, K; Ota, I; Sasaki, K; Tahara, M; Takahashi, S; Tanaka, K; Ueda, S; Ueda, T; Yokota, T | 1 |
| Akizuki, N; Hanawa, T; Hayashi, S; Ishii, N; Kawano, Y; Komoda, M; Sakai, H | 1 |
| Jang, HS; Jang, WS; Jin, YW; Kang, JK; Kim, MJ; Lee, SB; Lee, SJ; Lee, SS; Myung, HW; Myung, JK; Park, S; Shim, S | 1 |
| Ha, JM; Kim, JY; Kim, SH; Park, CW; Park, ES; Rhee, YS; Seo, JW | 1 |
| Fukui, K; Hayakari, R; Imaizumi, T; Matsumiya, T; Tanaka, H; Tanji, K; Tsuruga, K; Yachi, K; Yoshida, H | 1 |
| Chaitanya, B; Chhaparwal, Y; Fernandes, D; Pai, KM; Yathiraj, PH | 1 |
| Dohi, O; Doi, T; Fukui, A; Handa, O; Higashimura, Y; Horie, H; Horii, Y; Hotta, Y; Ishikawa, T; Itoh, Y; Kamada, K; Katada, K; Konishi, H; Majima, A; Mizushima, K; Morita, M; Murakami, T; Naito, Y; Okayama, T; Suyama, Y; Takagi, T; Tanaka, M; Toyokawa, Y; Uchiyama, K; Ueda, T; Uehara, Y; Ushiroda, C; Yasuda, T; Yasuda-Onozawa, Y; Yoshida, N | 1 |
| Akimoto, T; Fujimoto, A; Goto, O; Maehata, T; Mitsunaga, Y; Nishizawa, T; Ochiai, Y; Sasaki, M; Shimoda, M; Uraoka, T; Yahagi, N; Yamamoto, H | 1 |
| Hutami, IR; Izawa, T; Tanaka, E | 1 |
| Jang, H; Jang, WS; Jin, YW; Kim, H; Lee, C; Lee, J; Lee, SJ; Lee, SS; Myung, H; Myung, JK; Park, S; Shim, S | 1 |
| Higashide, T; Kawaguchi, C; Kawaguchi, I; Kobayashi, A; Sakurai, K; Sugiyama, K; Takeji, Y | 1 |
| Asano, RT; Fujimoto, SI; Imano, M; Itoh, T; Matsuda, T; Nishida, S; Satou, T; Takeda, T; Tsubaki, M | 1 |
| Choi, YK; Chung, JW; Gweon, TG; Kim, BW; Kim, CW; Kim, HG; Kim, JS; Park, JH; Park, SM | 1 |
| Fukagawa, K; Iwasaki, M; Okano, T; Saga, M; Sakata, M; Seika, D; Shimazaki, J | 1 |
| Fujimoto, C; Igarashi, T; Kobayashi, M; Suzuki, H; Takahashi, H; Yaguchi, C | 1 |
| Jaafar, MH; Mahadeva, S; Rampal, S; Safi, SZ; Tan, MP | 1 |
| Goto, H; Hattori, T; Katahira, H; Kumakura, S; Narimatsu, A; Tajima, K; Takahashi, H | 1 |
| Hanawa, T; Kawano, Y; Satoh, M | 1 |
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| Dohi, O; Fukui, A; Handa, O; Higashimura, Y; Ishikawa, T; Itoh, Y; Kamada, K; Katada, K; Konishi, H; Majima, A; Mukai, R; Naito, Y; Okayama, T; Suyama, Y; Takagi, T; Takayama, S; Uchiyama, K; Ushiroda, C; Yasuda-Onozawa, Y; Yoshida, N | 1 |
| Aoki, K; Dogru, M; Higa, K; Igarashi, A; Kojima, T; Shimazaki, J; Shimizu, T; Simsek, C; Tsubota, K | 1 |
| Cho, HJ; Kim, DD; Kim, KT; Lee, JY; Park, JH; Yoon, IS | 1 |
| Chung, JW; Kim, J; Kim, K; Kim, KO; Kim, SY; Kim, YJ; Kwon, KA; Lee, JS; Park, DK | 1 |
| Kamiki, Y; Makino, K; Takeuchi, I | 1 |
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| Hashita, T; Iwao, T; Kondo, S; Matsunaga, T; Mizuno, S | 1 |
| Ji, YW; Kang, HG; Kim, HC; Lee, HK; Moon, I; Noh, H; Song, JS; Yeo, A | 1 |
| Dogru, M; Igarashi, A; Kawakita, T; Kojima, T; Nagata, T; Ogawa, M; Shimazaki, J; Simsek, C; Tsubota, K | 1 |
| Fujii, M; Konishi, T; Nagamoto, H; Shibasaki, Y; Ueno, T; Yurikusa, T; Zenda, S | 1 |
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| Hakamata, A; Inui, N; Kashiwagura, Y; Namiki, N; Odagiri, K; Takano, H; Tanaka, S; Uchida, S; Watanabe, H | 1 |
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| Akhmadullina, OV; Belostotsky, NI; Bykova, SV; Dbar, SR; Khomeriki, SG; Parfenov, АI; Sabelnikova, EA | 1 |
| Chang, DK; Hong, SN; Kim, ER; Kim, HS; Kim, K; Kim, TJ; Kim, YH; Lee, YC | 1 |
| JeongWon, C; Jin-Sil, P; Kyung-Ah, J; Mi-La, C; SeungCheon, Y; Sun-Hee, H; Sung-Hwan, P | 1 |
| Dogru, M; Kojima, T; Nakamura, S; Simsek, C; Tsubota, K | 1 |
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| Kinoshita, S; Nakamura, T; Nakayama, T; Sotozono, C; Tanaka, H; Tsukamoto, M; Watanabe, A; Yokoi, N | 1 |
| Kodama, A; Koumoto, K; Nakagawa, A; Nonoguchi, Y; Sakurai, H; Suzuki, T; Yano, C | 1 |
| Hattori, Y; Kubota, S; Otsuka, M | 1 |
| Chung, H; Jung, DH; Kim, JH; Lee, SK; Lee, YC; Park, H; Park, JC; Park, JJ; Shin, SK; Youn, YH | 1 |
| Hou, D; Hu, Z; Yang, L; Yang, M | 1 |
| Gonik, MI; Ivashkin, VT; Trukhmanov, AS | 1 |
| Knyazev, OV; Parfenov, AI; Zvyaglova, MY | 1 |
| Cvijić, S; Dahan, A; Markovic, M; Zur, M | 1 |
| Jeong, Y; Ji, GE; Jin, H; Ju, JH; Kim, JW; Lee, J; Park, SH; Park, SJ | 1 |
| Abdel-Wahab, BA; Ali, FEM; Alkahtani, SA; Alshabi, AM; Hassanein, EHM; Mahnashi, MH | 1 |
| Cui, M; Geng, X; Liu, J; Xiong, Z | 1 |
| Cao, X; Jing, L; Mou, S; Xu, N; Yu, Z; Zhang, C | 1 |
| Inada, N; Shoji, J; Tomioka, A; Yamagami, S | 1 |
| Higaki, K; Maruyama, M; Masuda, K; Ogawara, KI; Okawa, S; Sumimoto, Y | 1 |
| Fujiwara, Y; Fukunaga, S; Hattori, M; Higashimori, A; Hosomi, S; Kamata, N; Kitamura, H; Kuzumoto, T; Nadatani, Y; Nagami, Y; Otani, K; Shiba, M; Shimada, S; Suda, W; Taira, K; Tanaka, F; Tanigawa, T; Watanabe, T | 1 |
| Andreev, DN; Maev, IV | 1 |
| Gupta, A; Jain, AK; Malhotra, C; Ram, J; Singh, H | 1 |
| Cho, SJ; Chun, HJ; Chung, IK; Jeon, HH; Jeon, SW; Joo, MK; Jung, SW; Kim, BW; Kim, GH; Kim, H; Kim, HS; Kim, JG; Kim, JW; Kim, KO; Kim, TN; Ko, KH; Lee, DH; Lee, HL; Lee, OJ; Lee, ST; Lim, YJ; Park, HJ; Park, JJ; Park, SJ; Sung, IK; Sung, JK | 1 |
| Cho, JH; Choi, HG; Ko, DW | 1 |
| Bae, HI; Jeon, SW; Kwon, YH; Lee, HS; Lee, JS; Nam, SY; Seo, AN | 1 |
| Alqarni, MA; El Ghobashy, MR; Farid, NF; Moatamed, RS; Naguib, IA | 1 |
| Li, Q; Wu, X; Xin, M | 1 |
| Chadha, R; Dureja, J; Jindal, A; Karan, M; Singh, R; Tomar, S | 1 |
| Kim, MG; Lee, JY; Yang, BR | 1 |
| Hazama, K; Imai, T; Kosuge, Y; Ootsuka, S; Suzuki, S | 1 |
| Bi, Y; Chen, X; He, Q; Jiang, K; Lei, Y; Li, P; Liang, H; Liu, M; Meng, H; Rong, Z; Sun, S; Wang, B; Xu, X; Zhao, J; Zheng, R | 1 |
| Cao, QR; Cui, JH; Jin, G; Lee, BJ; Ngo, HV; Park, C; Wang, J | 1 |
| Cao, QR; Cui, JH; Jin, G; Jung, M; Lee, BJ; Ngo, HV; Park, C; Wang, J | 1 |
| Jang, E; Jeong, JE; Kim, MG; Lee, JY; Park, M | 1 |
| Choi, YJ; Ha, YJ; Kang, EH; Kim, HS; Kim, KJ; Kim, N; Lee, DH; Lee, YJ; Liu, F; Oh, DJ; Park, YS; Shin, CM; Yoon, H | 1 |
| Bakulina, NV; Bolshakov, AO; Lutaenko, EA; Nekrasova, AS; Okovityi, SV; Prikhodko, VA; Tikhonov, SV | 1 |
| Choi, CY; Chung, SH; Chung, TY; Eom, Y; Hyon, JY; Kim, HK; Kim, HM; Kim, JY; Kim, MK; Ko, BY; Lee, HK; Lee, JS; Seo, KY; Song, JS; Yoon, KC | 1 |
32 review(s) available for alanine and opc 12759
| Article | Year |
|---|---|
Rebamipide: overview of its mechanisms of action and efficacy in mucosal protection and ulcer healing.
Topics: Alanine; Animals; Anti-Ulcer Agents; Clinical Trials as Topic; Disease Models, Animal; Gastric Mucosa; Humans; Prostaglandins; Quinolones; Recurrence; Stomach Ulcer | 1998 |
Role of oxygen radical and lipid peroxidation in indomethacin-induced gastric mucosal injury.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Free Radicals; Gastric Mucosa; Humans; Indomethacin; Lipid Peroxidation; Oxygen; Quinolones | 1998 |
In vitro studies indicating antioxidative properties of rebamipide.
Topics: Alanine; Animals; Anti-Ulcer Agents; Antioxidants; Gastric Mucosa; Humans; In Vitro Techniques; Lipid Peroxidation; Neutrophils; Quinolones; Reactive Oxygen Species | 1998 |
Helicobacter pylori infection, oxidative DNA damage, gastric carcinogenesis, and reversibility by rebamipide.
Topics: Alanine; Antioxidants; Apoptosis; DNA Damage; Helicobacter Infections; Helicobacter pylori; Humans; Oxidative Stress; Quinolones; Stomach Neoplasms | 1998 |
Benign gastric ulcer associated with Canidida infection in a healthy adult.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Alanine; Anti-Infective Agents; Anti-Ulcer Agents; Candidiasis; Carnosine; Humans; Lansoprazole; Male; Middle Aged; Omeprazole; Organometallic Compounds; Quinolones; Stomach Ulcer; Zinc; Zinc Compounds | 1999 |
[Rebamipide].
Topics: Alanine; Anti-Ulcer Agents; Antioxidants; Cytokines; Drug Therapy, Combination; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Inflammation Mediators; Neutrophil Activation; Oxidative Stress; Peptic Ulcer; Quinolones; Urease | 2002 |
Chemoprevention of Helicobacter pylori-associated gastric carcinogenesis in a mouse model: is it possible?
Topics: Alanine; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cytokines; Disease Models, Animal; Helicobacter Infections; Helicobacter pylori; Humans; Methylnitrosourea; Mice; NF-kappa B; Quinolones; Stomach Neoplasms; Sulfonamides | 2003 |
Review article: the role of rebamipide in the management of inflammatory disease of the gastrointestinal tract.
Topics: Alanine; Anti-Ulcer Agents; Cells, Cultured; Clinical Trials as Topic; Colitis; Gastritis; Helicobacter Infections; Humans; Models, Biological; Quinolones | 2003 |
Review article: rebamipide and the digestive epithelial barrier.
Topics: Alanine; Anti-Ulcer Agents; Antigens, Bacterial; Biological Transport; Digestive System; Epithelial Cells; Helicobacter pylori; Humans; Intestinal Absorption; Quinolones | 2003 |
Review article: clinical significance of mucosal-protective agents: acid, inflammation, carcinogenesis and rebamipide.
Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Anticarcinogenic Agents; Gastric Acid; Gastric Mucosa; Gastritis; Humans; Quinolones; Stomach Neoplasms | 2003 |
[Enema therapy for ulcerative colitis patients].
Topics: Abietanes; Alanine; Anesthetics, Local; Betamethasone; Colitis, Ulcerative; Enema; Fatty Acids, Volatile; Humans; Mesalamine; Quinolones; Severity of Illness Index; Sucralfate | 2005 |
15th anniversary of rebamipide: looking ahead to the new mechanisms and new applications.
Topics: Alanine; Anti-Ulcer Agents; Antioxidants; Chemoprevention; Growth Substances; Humans; Peptic Ulcer; Quinolones; Randomized Controlled Trials as Topic; Wound Healing | 2005 |
[Quality of ulcer healing and rebamipide].
Topics: Alanine; Amoxicillin; Animals; Anti-Ulcer Agents; Antioxidants; Cytokines; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Omeprazole; Quinolones; Recurrence; Stomach Ulcer; Wound Healing | 2005 |
Oxidative stress involvement and gene expression in indomethacin-induced gastropathy.
Topics: Alanine; Animals; Anti-Ulcer Agents; Apoptosis; DNA; Gastric Mucosa; Gene Expression Profiling; Gene Expression Regulation; Humans; Indomethacin; Neutrophils; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Quinolones; Rats; Reactive Oxygen Species; Stomach Diseases | 2006 |
[Side effects of gastric muco-protective agents].
Topics: Adjuvants, Pharmaceutic; Alanine; Alprostadil; Aluminum; Anti-Ulcer Agents; Diterpenes; Drug Interactions; Gastric Acid; Gastric Emptying; Humans; Hydrogen-Ion Concentration; Misoprostol; Quinolones; Sulpiride; Tranexamic Acid | 2007 |
Gastric ulcerogenic and healing impairment actions of alendronate, a nitrogen-containing bisphosphonate - prophylactic effects of rebamipide.
Topics: Alanine; Alendronate; Animals; Anti-Ulcer Agents; Bone Density Conservation Agents; Humans; Quinolones; Stomach Ulcer; Wound Healing | 2011 |
Rebamipide helps defend against nonsteroidal anti-inflammatory drugs induced gastroenteropathy: a systematic review and meta-analysis.
Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Gastrointestinal Agents; Gastrointestinal Diseases; Humans; Protective Agents; Quinolones; Randomized Controlled Trials as Topic | 2013 |
Efficacy and safety of proton pump inhibitors (PPIs) plus rebamipide for endoscopic submucosal dissection-induced ulcers: a meta-analysis.
Topics: Alanine; Anti-Ulcer Agents; Dissection; Drug Therapy, Combination; Endoscopy; Humans; Proton Pump Inhibitors; Quinolones; Randomized Controlled Trials as Topic; Stomach Ulcer | 2014 |
Rebamipide plus proton pump inhibitor versus proton pump inhibitor alone in the treatment of endoscopic submucosal dissection-induced gastric ulcer: a meta-analysis of randomized controlled trials.
Topics: Adenoma; Aged; Aged, 80 and over; Alanine; Anti-Ulcer Agents; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Female; Humans; Male; Middle Aged; Proton Pump Inhibitors; Quinolones; Randomized Controlled Trials as Topic; Stomach Neoplasms; Stomach Ulcer; Treatment Outcome | 2014 |
Interventions for the management of oral ulcers in Behçet's disease.
Topics: Acyclovir; Adrenal Cortex Hormones; Alanine; Behcet Syndrome; Colchicine; Cyclosporine; Etanercept; Humans; Immunoglobulin G; Interferon-alpha; Oral Ulcer; Quinolones; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Stomatitis, Aphthous; Sucralfate; Thalidomide | 2014 |
Effect of supplementation with rebamipide for Helicobacter pylori eradication therapy: a systematic review and meta-analysis.
Topics: Alanine; Amoxicillin; Databases, Bibliographic; Drug Therapy, Combination; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Odds Ratio; Proton Pump Inhibitors; Quinolones; Randomized Controlled Trials as Topic; Treatment Outcome | 2014 |
[Rebamipide: New opportunities of gastroenteroprotection].
Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Humans; Quinolones | 2015 |
Microbiota Plays a Key Role in Non-Steroidal Anti-Inflammatory Drug-Induced Small Intestinal Damage.
Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Gastrointestinal Microbiome; Humans; Intestinal Diseases; Intestine, Small; Probiotics; Quinolones; Ulcer | 2017 |
Potential Role of Rebamipide in Osteoclast Differentiation and Mandibular Condylar Cartilage Homeostasis.
Topics: Alanine; Animals; Antioxidants; Cartilage, Articular; Cell Differentiation; Homeostasis; Humans; Mandibular Condyle; Osteoarthritis; Osteoclasts; Quinolones; Temporomandibular Joint; Temporomandibular Joint Disorders | 2018 |
Efficacy of Rebamipide in Organic and Functional Dyspepsia: A Systematic Review and Meta-Analysis.
Topics: Alanine; Anti-Ulcer Agents; Dyspepsia; Humans; Odds Ratio; Quinolones; Treatment Outcome | 2018 |
Tear Film-Oriented Diagnosis and Tear Film-Oriented Therapy for Dry Eye Based on Tear Film Dynamics.
Topics: Alanine; Antioxidants; Dry Eye Syndromes; Humans; Japan; Mucins; Ophthalmic Solutions; Polyphosphates; Quinolones; Tears; Uracil Nucleotides; Wettability | 2018 |
Medical Treatment for Dry Eye in Japan.
Topics: Alanine; Dry Eye Syndromes; Humans; Japan; Lubricant Eye Drops; Polyphosphates; Quinolones; Tears; Uracil Nucleotides | 2018 |
Secreted Mucins on the Ocular Surface.
Topics: Alanine; Conjunctiva; Dry Eye Syndromes; Goblet Cells; Humans; Mucin 5AC; Ophthalmic Solutions; Polyphosphates; Quinolones; Uracil Nucleotides | 2018 |
[Development of Hospital Formulations Based on Medical Need].
Topics: Alanine; Cellulose; Chemical Phenomena; Drug Compounding; Drug-Related Side Effects and Adverse Reactions; Humans; Mouthwashes; Nanoparticles; Pharmacy Service, Hospital; Quinolones; Radiotherapy; Sodium Dodecyl Sulfate; Solubility; Solutions; Stomatitis | 2019 |
[Pharmacological and clinical feature of rebamipide: new therapeutic targets].
Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Quinolones | 2020 |
Rebamipide with Proton Pump Inhibitors (PPIs) versus PPIs Alone for the Treatment of Endoscopic Submucosal Dissection-Induced Ulcers: A Meta-analysis.
Topics: Alanine; Anti-Ulcer Agents; Endoscopic Mucosal Resection; Female; Humans; Male; Middle Aged; Proton Pump Inhibitors; Quinolones; Stomach Ulcer | 2020 |
[Pharmacokinetics and pharmacodynamics of rebamipide. New possibilities of therapy: A review].
Topics: Alanine; Biological Availability; Humans; Quinolones | 2023 |
82 trial(s) available for alanine and opc 12759
| Article | Year |
|---|---|
[Protective effect of rebamipide (OPC-12759) on the gastric mucosa in rats and humans].
Topics: Adult; Alanine; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Double-Blind Method; Gastric Mucosa; Hemoglobins; Humans; Male; Microcirculation; Oxygen; Quinolones; Rats; Rats, Inbred Strains; Regional Blood Flow; Stomach Ulcer | 1991 |
Local gastric and serum concentrations of rebamipide following oral administration to patients with chronic gastritis.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Anti-Ulcer Agents; Chromatography, High Pressure Liquid; Chronic Disease; Female; Gastric Mucosa; Gastritis; Humans; Male; Middle Aged; Quinolones | 1996 |
Augmented eradication rates of Helicobacter pylori by new combination therapy with lansoprazole, amoxicillin, and rebamipide.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Alanine; Amoxicillin; Anti-Infective Agents; Anti-Ulcer Agents; Antioxidants; Chemokines; Cytokines; Drug Therapy, Combination; Gastric Mucosa; Helicobacter Infections; Humans; Lansoprazole; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Omeprazole; Penicillins; Peptic Ulcer; Prospective Studies; Proton Pump Inhibitors; Quinolones | 1998 |
Rebamipide protects against indomethacin-induced gastric mucosal injury in healthy volunteers in a double-blind, placebo-controlled study.
Topics: Adult; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Cytokines; Double-Blind Method; Gastric Mucosa; Humans; Indomethacin; Lipid Peroxidation; Male; Peroxidase; Quinolones; Reference Values; Stomach Ulcer; Treatment Outcome | 1998 |
Rebamipide prevents recurrence of gastric ulcers without affecting Helicobacter pylori status.
Topics: Aged; Alanine; Anti-Ulcer Agents; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Quinolones; Recurrence; Stomach Ulcer; Treatment Outcome | 1998 |
Quantitative and qualitative usefulness of rebamipide in eradication regimen of Helicobacter pylori.
Topics: Adult; Aged; Alanine; Antioxidants; Apoptosis; Catalase; Cytokines; Drug Therapy, Combination; Enzyme Inhibitors; Female; Gastric Mucosa; Glutathione Peroxidase; Helicobacter Infections; Helicobacter pylori; Humans; Lipid Peroxidation; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Quinolones; Reactive Oxygen Species; Superoxide Dismutase; Treatment Outcome | 1998 |
Effects of rebamipide in combination with lansoprazole and amoxicillin on Helicobacter pylori-infected gastric ulcer patients.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Alanine; Amoxicillin; Anti-Ulcer Agents; Diterpenes; Drug Therapy, Combination; Enzyme Inhibitors; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Male; Middle Aged; Omeprazole; Penicillins; Proton Pump Inhibitors; Quinolones; Stomach Ulcer; Treatment Outcome | 1998 |
Effect of rebamipide on Helicobacter pylori infection in patients with peptic ulcer.
Topics: Adult; Aged; Alanine; Amoxicillin; Anti-Ulcer Agents; Drug Therapy, Combination; Duodenal Ulcer; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Omeprazole; Penicillins; Peptic Ulcer; Quinolones; Stomach Ulcer; Treatment Outcome | 1998 |
Rebamipide prevents occurrence of gastric lesions following transcatheter arterial embolization in the hepatic artery.
Topics: Adult; Aged; Alanine; Carcinoma, Hepatocellular; Embolization, Therapeutic; Esophageal and Gastric Varices; Female; Gastric Mucosa; Hepatic Artery; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Liver Function Tests; Liver Neoplasms; Male; Middle Aged; Quinolones; Stomach Ulcer | 1999 |
A short-term eradication therapy for Helicobacter pylori acute gastritis.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Disease; Adolescent; Adult; Alanine; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Female; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Male; Middle Aged; Omeprazole; Penicillins; Quinolones; Stomach; Time Factors | 2000 |
Double-blind placebo-controlled multicentre studies of rebamipide, a gastroprotective drug, in the treatment of functional dyspepsia with or without Helicobacter pylori infection.
Topics: Abdominal Pain; Adult; Alanine; Antacids; Anti-Ulcer Agents; Double-Blind Method; Dyspepsia; Eructation; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Quinolones; Treatment Outcome | 2001 |
[Effect of antiulcer agents on the urea breath test--Comparison between rebamipide and ecabet sodium].
Topics: Abietanes; Alanine; Anti-Ulcer Agents; Breath Tests; Diterpenes; False Negative Reactions; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Predictive Value of Tests; Quinolones; Urea | 2002 |
Effect of rebamipide in treatment of Helicobacter pylori-associated duodenal ulcer: attenuation of chemokine expression and nitrosative damage.
Topics: Adult; Alanine; Antioxidants; Chemokine CCL5; Cytokines; Drug Therapy, Combination; Duodenal Ulcer; Enzyme-Linked Immunosorbent Assay; Female; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Immunohistochemistry; Interleukin-1; Interleukin-8; Male; Quinolones; Tumor Necrosis Factor-alpha; Tyrosine | 2002 |
Long-term rebamipide therapy improves Helicobacter pylori-associated chronic gastritis.
Topics: Alanine; Anti-Ulcer Agents; Drug Administration Schedule; Gastrins; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pepsinogens; Quinolones; Stomach | 2002 |
Influence of lansoprazole, famotidine, roxatidine and rebamipide administration on the urea breath test for the diagnosis of Helicobacter pylori infection.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Alanine; Anti-Ulcer Agents; Breath Tests; False Negative Reactions; Famotidine; Female; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Male; Omeprazole; Piperidines; Predictive Value of Tests; Quinolones; Urea | 2003 |
Efficacy of rebamipide as adjunctive therapy in the treatment of recurrent oral aphthous ulcers in patients with Behçet's disease: a randomised, double-blind, placebo-controlled study.
Topics: Adult; Aged; Alanine; Anti-Ulcer Agents; Behcet Syndrome; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Prospective Studies; Quinolones; Recurrence; Stomatitis, Aphthous | 2003 |
Effects of rebamipide, a gastro-protective drug on the Helicobacter pylori status and inflammation in the gastric mucosa of patients with gastric ulcer: a randomized double-blind placebo-controlled multicentre trial.
Topics: Adult; Aged; Alanine; Anti-Ulcer Agents; Double-Blind Method; Female; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Quinolones; Stomach Ulcer | 2003 |
Radical scavengers for Ménière's disease after failure of conventional therapy: a pilot study.
Topics: Adult; Aged; Alanine; Antioxidants; Ascorbic Acid; Female; Free Radical Scavengers; Glutathione; Hearing Loss; Humans; Male; Meniere Disease; Middle Aged; Pilot Projects; Quinolones; Tinnitus; Treatment Failure; Vertigo | 2003 |
Preoperative administration of rebamipide significantly lowers body temperature and circulating interleukin-6 in gastric cancer patients after gastrectomy.
Topics: Aged; Alanine; Chemoprevention; Enzyme Inhibitors; Female; Fever; Gastrectomy; Humans; Interleukin-6; Laparoscopy; Male; Middle Aged; Prospective Studies; Quinolones; Stomach Neoplasms; Systemic Inflammatory Response Syndrome; Treatment Outcome | 2003 |
Rebamipide enemas-new effective treatment for patients with corticosteroid dependent or resistant ulcerative colitis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Alanine; Anti-Ulcer Agents; Colitis, Ulcerative; Drug Resistance; Enema; Female; Humans; Male; Middle Aged; Patient Satisfaction; Quinolones; Severity of Illness Index | 2005 |
A pilot study to evaluate a new combination therapy for gastric ulcer: Helicobacter pylori eradication therapy followed by gastroprotective treatment with rebamipide.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Alanine; Amoxicillin; Anti-Infective Agents; Anti-Ulcer Agents; Breath Tests; Clarithromycin; Drug Therapy, Combination; Female; Gastroscopy; Helicobacter Infections; Helicobacter pylori; Humans; Japan; Lansoprazole; Male; Middle Aged; Pilot Projects; Quinolones; Stomach Ulcer; Treatment Outcome | 2006 |
Ambroxol for the prevention of acute upper respiratory disease.
Topics: Aged; Aged, 80 and over; Alanine; Ambroxol; Carbocysteine; Female; Humans; Male; Quinolones; Respiratory Tract Infections | 2006 |
Effect of a gastro-protective agent, rebamipide, on symptom improvement in patients with functional dyspepsia: a double-blind placebo-controlled study in Japan.
Topics: Adult; Aged; Alanine; Anti-Ulcer Agents; Double-Blind Method; Dyspepsia; Female; Follow-Up Studies; Humans; Japan; Male; Middle Aged; Pain Measurement; Quality of Life; Quinolones; Retrospective Studies; Surveys and Questionnaires; Treatment Outcome | 2006 |
Assessing the efficacy of famotidine and rebamipide in the treatment of gastric mucosal lesions in patients receiving long-term NSAID therapy (FORCE--famotidine or rebamipide in comparison by endoscopy).
Topics: Adult; Aged; Alanine; Anti-Ulcer Agents; Endoscopy, Gastrointestinal; Famotidine; Female; Gastric Mucosa; Humans; Male; Middle Aged; Peptic Ulcer Hemorrhage; Quinolones; Stomach Ulcer | 2006 |
Rebamipide enema therapy as a treatment for patients with active distal ulcerative colitis.
Topics: Adolescent; Adult; Aged; Alanine; Anti-Ulcer Agents; Colitis, Ulcerative; Enema; Female; Humans; Male; Middle Aged; Quinolones | 2007 |
Preventive effects of rebamipide on NSAID-induced gastric mucosal injury and reduction of gastric mucosal blood flow in healthy volunteers.
Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Female; Gastric Mucosa; Humans; Ibuprofen; Male; Middle Aged; Quinolones | 2007 |
Rebamipide, a gastro-protective and anti-inflammatory drug, promotes gastric ulcer healing following eradication therapy for Helicobacter pylori in a Japanese population: a randomized, double-blind, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Alanine; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Double-Blind Method; Endoscopy, Gastrointestinal; Enzyme Inhibitors; Female; Follow-Up Studies; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Japan; Lansoprazole; Male; Middle Aged; Prevalence; Proton Pump Inhibitors; Quinolones; Retrospective Studies; Stomach Ulcer; Treatment Outcome | 2007 |
Anti-inflammatory effects of rebamipide according to Helicobacter pylori status in patients with chronic erosive gastritis: a randomized sucralfate-controlled multicenter trial in China-STARS study.
Topics: Adult; Alanine; Anti-Inflammatory Agents; Anti-Ulcer Agents; China; Dinoprostone; Female; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Male; Malondialdehyde; Middle Aged; Quinolones; Sucralfate | 2008 |
Rebampide enema therapy as a treatment for patients with chronic radiation proctitis: initial treatment or when other methods of conservative management have failed.
Topics: Aged; Alanine; Antioxidants; Enema; Female; Genital Neoplasms, Female; Humans; Middle Aged; Proctitis; Quinolones; Radiation Injuries | 2008 |
An open-labeled study of rebamipide treatment in chronic gastritis patients with dyspeptic symptoms refractory to proton pump inhibitors.
Topics: Adult; Alanine; Anti-Ulcer Agents; Chronic Disease; Dyspepsia; Endoscopy, Gastrointestinal; Endpoint Determination; Female; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Proton Pump Inhibitors; Quinolones; Thailand; Young Adult | 2008 |
Efficacy of rebamipide for diclofenac-induced small-intestinal mucosal injuries in healthy subjects: a prospective, randomized, double-blinded, placebo-controlled, cross-over study.
Topics: Adult; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Capsule Endoscopy; Cross-Over Studies; Diclofenac; Double-Blind Method; Female; Follow-Up Studies; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Prospective Studies; Quinolones; Severity of Illness Index; Treatment Outcome | 2008 |
[A pilot study of rebamipide-gargle for chemoradiotherapy-induced mucositis in oral cancer patients].
Topics: Aged; Aged, 80 and over; Alanine; Antineoplastic Agents; Combined Modality Therapy; Female; Humans; Male; Middle Aged; Mouth Neoplasms; Mouthwashes; Mucositis; Pilot Projects; Quinolones | 2008 |
Efficacy and safety of rebamipide for the treatment of dry mouth symptoms in patients with Sjögren's syndrome: a double-blind placebo-controlled multicenter trial.
Topics: Aged; Alanine; Anti-Inflammatory Agents; Double-Blind Method; Eating; Female; Humans; Male; Middle Aged; Mouth; Prostaglandins; Quinolones; Saliva; Sjogren's Syndrome; Sleep; Treatment Outcome; Xerostomia | 2009 |
Circadian variations of gastrointestinal mucosal damage detected with transnasal endoscopy in apparently healthy subjects treated with low-dose aspirin (ASA) for a short period.
Topics: Adult; Alanine; Aspirin; Circadian Rhythm; Double-Blind Method; Endoscopy; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Quinolones; Time Factors; Treatment Outcome; Ulcer; Young Adult | 2009 |
Effect of rebamipide on gastric ulcer healing caused by Helicobacter pylori and/or NSAIDs or non NSAIDs-non H. pylori.
Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Female; Follow-Up Studies; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Quinolones; Stomach Ulcer; Treatment Outcome | 2009 |
Clinical trial: rebamipide promotes gastric ulcer healing by proton pump inhibitor after endoscopic submucosal dissection--a randomized controlled study.
Topics: Administration, Oral; Aged; Aged, 80 and over; Alanine; Anti-Ulcer Agents; Drug Synergism; Drug Therapy, Combination; Female; Gastric Mucosa; Humans; Male; Medication Adherence; Middle Aged; Prospective Studies; Proton Pump Inhibitors; Quinolones; Stomach Ulcer | 2010 |
Pharmacokinetics and bioequivalence of two formulations of rebamipide 100-mg tablets: a randomized, single-dose, two-period, two-sequence crossover study in healthy Korean male volunteers.
Topics: Adult; Alanine; Anti-Ulcer Agents; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cross-Over Studies; Genotype; Humans; Male; Polymorphism, Genetic; Quinolones; Regression Analysis; Sample Size; Solubility; Tablets; Therapeutic Equivalency; Young Adult | 2009 |
Management of recurrence of symptoms of gastroesophageal reflux disease: synergistic effect of rebamipide with 15 mg lansoprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Alanine; Anti-Ulcer Agents; Drug Synergism; Drug Therapy, Combination; Female; Gastroesophageal Reflux; Humans; Lansoprazole; Male; Middle Aged; Quinolones; Secondary Prevention | 2010 |
Rebamipide may be comparable to H2 receptor antagonist in healing iatrogenic gastric ulcers created by endoscopic mucosal resection: a prospective randomized pilot study.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Anti-Ulcer Agents; Endoscopy, Gastrointestinal; Famotidine; Histamine H2 Antagonists; Humans; Iatrogenic Disease; Male; Middle Aged; Pilot Projects; Prospective Studies; Quinolones; Receptors, Histamine H2; Stomach Ulcer; Wound Healing | 2010 |
Rebamipide has the potential to reduce the intensity of NSAID-induced small intestinal injury: a double-blind, randomized, controlled trial evaluated by capsule endoscopy.
Topics: Adult; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Capsule Endoscopy; Diclofenac; Double-Blind Method; Humans; Intestinal Mucosa; Intestine, Small; Male; Middle Aged; Omeprazole; Quinolones; Treatment Outcome; Young Adult | 2011 |
Evaluation of small bowel blood flow in healthy subjects receiving low-dose aspirin.
Topics: Adult; Alanine; Anti-Ulcer Agents; Area Under Curve; Aspirin; Blood Flow Velocity; Contrast Media; Cross-Over Studies; Double-Blind Method; Endoscopy; Humans; Intestine, Small; Male; Placebos; Quinolones; Treatment Outcome; Ultrasonography | 2011 |
A randomized controlled trial of rebamipide plus rabeprazole for the healing of artificial ulcers after endoscopic submucosal dissection.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Alanine; Anti-Ulcer Agents; Disease Progression; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Gastritis, Atrophic; Gastroscopy; Humans; Male; Middle Aged; Prospective Studies; Proton Pump Inhibitors; Quinolones; Rabeprazole; Severity of Illness Index; Stomach Neoplasms; Stomach Ulcer | 2011 |
Healing effects of rebamipide and omeprazole in Helicobacter pylori-positive gastric ulcer patients after eradication therapy: a randomized double-blind, multinational, multi-institutional comparative study.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Double-Blind Method; Female; Helicobacter Infections; Helicobacter pylori; Humans; Intention to Treat Analysis; Male; Middle Aged; Omeprazole; Quinolones; Stomach Ulcer; Treatment Outcome; Wound Healing; Young Adult | 2011 |
[Pilot study on clinical effects of rebamipide gargle against oral mucositis induced by fluoropyrimidines].
Topics: Alanine; Antimetabolites, Antineoplastic; Colonic Neoplasms; Fluorouracil; Humans; Mouthwashes; Pilot Projects; Prospective Studies; Quinolones; Stomach Neoplasms; Stomatitis | 2011 |
Contributing factors to gastric ulcer healing after endoscopic submucosal dissection including the promoting effect of rebamipide.
Topics: Aged; Aged, 80 and over; Alanine; Anti-Ulcer Agents; Drug Therapy, Combination; Endoscopy, Digestive System; Female; Follow-Up Studies; Gastric Mucosa; Humans; Iatrogenic Disease; Male; Middle Aged; Multivariate Analysis; Neovascularization, Physiologic; Prospective Studies; Proton Pump Inhibitors; Quinolones; Stomach Neoplasms; Stomach Ulcer; Time Factors; Treatment Outcome; Wound Healing | 2012 |
Aspirin-induced small bowel injuries and the preventive effect of rebamipide.
Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Cross-Over Studies; Double-Blind Method; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Middle Aged; Omeprazole; Placebos; Quinolones; Young Adult | 2011 |
Can rebamipide and proton pump inhibitor combination therapy promote the healing of endoscopic submucosal dissection-induced ulcers? A randomized, prospective, multicenter study.
Topics: Adenoma; Aged; Alanine; Anti-Ulcer Agents; Carcinoma; Chi-Square Distribution; Confidence Intervals; Dissection; Drug Therapy, Combination; Female; Gastric Mucosa; Gastroscopy; Humans; Male; Middle Aged; Odds Ratio; Proton Pump Inhibitors; Quinolones; Stomach Neoplasms; Stomach Ulcer | 2012 |
A study on the efficacy of rebamipide for patients with proton pump inhibitor-refractory non-erosive reflux disease.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Alanine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Esophageal pH Monitoring; Esophagoscopy; Female; Follow-Up Studies; Gastroesophageal Reflux; Humans; Lansoprazole; Male; Middle Aged; Prospective Studies; Proton Pump Inhibitors; Quinolones; Recurrence; Reference Values; Risk Assessment; Severity of Illness Index; Statistics, Nonparametric; Treatment Outcome; Young Adult | 2012 |
Rebamipide (OPC-12759) in the treatment of dry eye: a randomized, double-masked, multicenter, placebo-controlled phase II study.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Antioxidants; Coloring Agents; Dose-Response Relationship, Drug; Double-Blind Method; Dry Eye Syndromes; Enzyme Inhibitors; Female; Fluorescein; Fluorophotometry; Humans; Lissamine Green Dyes; Male; Middle Aged; Ophthalmic Solutions; Quinolones; Treatment Outcome; Young Adult | 2012 |
Development of a simple LC-MS/MS method for determination of rebamipide in human plasma and its application to a bioequivalence study.
Topics: Alanine; Anti-Ulcer Agents; Area Under Curve; Calibration; Chromatography, High Pressure Liquid; Cross-Over Studies; Cyclohexanols; Female; Half-Life; Humans; Male; Quality Control; Quinolones; Reproducibility of Results; Tablets; Tandem Mass Spectrometry; Therapeutic Equivalency; Venlafaxine Hydrochloride; Young Adult | 2012 |
The efficacy of rebamipide add-on therapy in arthritic patients with COX-2 selective inhibitor-related gastrointestinal events: a prospective, randomized, open-label blinded-endpoint pilot study by the GLORIA study group.
Topics: Alanine; Arthritis, Rheumatoid; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Enzyme Inhibitors; Female; Gastrointestinal Diseases; Humans; Low Back Pain; Male; Middle Aged; Osteoarthritis; Pilot Projects; Pyrazoles; Quinolones; Sulfonamides; Treatment Outcome; Upper Gastrointestinal Tract | 2013 |
A randomized, multicenter phase 3 study comparing 2% rebamipide (OPC-12759) with 0.1% sodium hyaluronate in the treatment of dry eye.
Topics: Adult; Aged; Alanine; Anti-Ulcer Agents; Coloring Agents; Conjunctiva; Dry Eye Syndromes; Female; Fluorophotometry; Humans; Hyaluronic Acid; Lissamine Green Dyes; Male; Middle Aged; Ophthalmic Solutions; Quinolones; Tears; Treatment Outcome; Viscosupplements; Visual Acuity; Young Adult | 2013 |
A randomized, double-blinded, placebo-controlled, multicenter trial, healing effect of rebamipide in patients with low-dose aspirin and/or non-steroidal anti-inflammatory drug induced small bowel injury.
Topics: Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Dietary Proteins; Double-Blind Method; Female; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Middle Aged; Quinolones; Wound Healing | 2014 |
Efficacy of treatment with rebamipide for endoscopic submucosal dissection-induced ulcers.
Topics: Adenocarcinoma; Aged; Alanine; Anti-Ulcer Agents; Dissection; Female; Gastroscopy; Humans; Iatrogenic Disease; Lansoprazole; Male; Middle Aged; Peptic Ulcer; Prospective Studies; Proton Pump Inhibitors; Quinolones; Stomach Neoplasms | 2013 |
A randomized, double-blind, placebo-controlled study of rebamipide for gastric mucosal injury taking aspirin with or without clopidogrel.
Topics: Adult; Alanine; Anti-Ulcer Agents; Aspirin; Clopidogrel; Double-Blind Method; Gastric Mucosa; Gastrointestinal Hemorrhage; Healthy Volunteers; Humans; Male; Peptic Ulcer; Platelet Aggregation Inhibitors; Quinolones; Ticlopidine; Young Adult | 2014 |
Preventive efficacy and safety of rebamipide in nonsteroidal anti-inflammatory drug-induced mucosal toxicity.
Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Butanones; Diclofenac; Double-Blind Method; Drug Administration Schedule; Gastric Mucosa; Humans; Meloxicam; Middle Aged; Misoprostol; Nabumetone; Quinolones; Stomach Ulcer; Thiazines; Thiazoles; Treatment Outcome | 2014 |
Efficacy and safety of 1-week Helicobacter pylori eradication therapy and 7-week rebamipide treatment after endoscopic submucosal dissection of early gastric cancer in comparison with 8-week PPI standard treatment: a randomized, controlled, prospective, m
Topics: Aged; Alanine; Anti-Bacterial Agents; Clarithromycin; Dissection; Early Detection of Cancer; Female; Gastric Mucosa; Gastroscopy; Helicobacter Infections; Humans; Male; Middle Aged; Omeprazole; Proton Pump Inhibitors; Quinolones; Stomach Neoplasms; Stomach Ulcer; Treatment Outcome | 2015 |
A multicenter, randomized, double-blind, placebo-controlled trial of high-dose rebamipide treatment for low-dose aspirin-induced moderate-to-severe small intestinal damage.
Topics: Aged; Alanine; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Intestinal Diseases; Intestine, Small; Male; Quinolones; Severity of Illness Index; Treatment Outcome | 2015 |
Effect of Rebamipide Ophthalmic Suspension on Intraocular Light Scattering for Dry Eye After Corneal Refractive Surgery.
Topics: Administration, Topical; Adult; Alanine; Anti-Ulcer Agents; Dry Eye Syndromes; Female; Humans; Keratomileusis, Laser In Situ; Lasers, Excimer; Light; Male; Middle Aged; Myopia; Postoperative Complications; Prospective Studies; Quinolones; Scattering, Radiation; Suspensions; Tears; Young Adult | 2015 |
Rebamipide improves chronic inflammation in the lesser curvature of the corpus after Helicobacter pylori eradication: a multicenter study.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Female; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Inflammation; Male; Middle Aged; Quinolones; Stomach | 2015 |
Effect of Rebamipide on the Premalignant Progression of Chronic Gastritis: A Randomized Controlled Study.
Topics: Alanine; CDX2 Transcription Factor; Disease Progression; Female; Gastric Mucosa; Gastritis; Helicobacter Infections; Homeodomain Proteins; Humans; Male; Metaplasia; Middle Aged; Peptides; Precancerous Conditions; Quinolones; Stomach Neoplasms; Trefoil Factor-3 | 2015 |
Improvements in Signs and Symptoms of Dry Eye after Instillation of 2% Rebamipide.
Topics: Alanine; Dry Eye Syndromes; Female; Humans; Male; Ophthalmic Solutions; Quinolones; Treatment Outcome | 2015 |
Effect of topical rebamipide on conjunctival goblet cell recovery after vitrectomy.
Topics: Aged; Alanine; Cell Count; Conjunctiva; Female; Goblet Cells; Humans; Male; Middle Aged; Quinolones; Retinal Diseases; Time Factors; Treatment Outcome; Vitrectomy | 2016 |
Rebamipide does not protect against naproxen-induced gastric damage: a randomized double-blind controlled trial.
Topics: Adolescent; Adult; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Double-Blind Method; Female; Gastric Mucosa; Gastrointestinal Agents; Humans; Male; Middle Aged; Naproxen; Quinolones; Stomach Diseases; Young Adult | 2016 |
Limited Effect of Rebamipide in Addition to Proton Pump Inhibitor (PPI) in the Treatment of Post-Endoscopic Submucosal Dissection Gastric Ulcers: A Randomized Controlled Trial Comparing PPI Plus Rebamipide Combination Therapy with PPI Monotherapy.
Topics: Adenoma; Aged; Alanine; Anti-Ulcer Agents; Drug Therapy, Combination; Endoscopic Mucosal Resection; Female; Gastric Mucosa; Humans; Male; Middle Aged; Postoperative Complications; Prospective Studies; Proton Pump Inhibitors; Quinolones; Rabeprazole; Stomach Neoplasms; Stomach Ulcer; Treatment Outcome | 2016 |
The Benefits of Combination Therapy with Esomeprazole and Rebamipide in Symptom Improvement in Reflux Esophagitis: An International Multicenter Study.
Topics: Adult; Alanine; Drug Administration Schedule; Drug Therapy, Combination; Esomeprazole; Esophagitis, Peptic; Female; Humans; Male; Middle Aged; Prospective Studies; Proton Pump Inhibitors; Quinolones; Severity of Illness Index; Treatment Outcome | 2016 |
Rebamipide to Manage Stomatopyrosis in Oral Submucous Fibrosis.
Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents; Betamethasone; Female; Humans; Male; Middle Aged; Oral Submucous Fibrosis; Pain Measurement; Prospective Studies; Quinolones; Tobacco, Smokeless | 2016 |
Population pharmacokinetic analysis of rebamipide in healthy Korean subjects with the characterization of atypical complex absorption kinetics.
Topics: Administration, Oral; Adult; Alanine; Anti-Ulcer Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Gastrointestinal Absorption; Healthy Volunteers; Humans; Male; Quinolones; Republic of Korea; Young Adult | 2017 |
Efficacy and safety of rebamipide liquid for chemoradiotherapy-induced oral mucositis in patients with head and neck cancer: a multicenter, randomized, double-blind, placebo-controlled, parallel-group phase II study.
Topics: Adult; Aged; Alanine; Chemoradiotherapy; Dose-Response Relationship, Drug; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Quinolones; Stomatitis | 2017 |
Rebamipide gargle in preventive management of chemo-radiotherapy induced oral mucositis.
Topics: Adult; Aged; Alanine; Case-Control Studies; Chemoradiotherapy; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Mouthwashes; Placebos; Quinolones; Radiotherapy, Conformal; Radiotherapy, Intensity-Modulated; Stomatitis | 2017 |
A Prospective, Randomized Trial of Two Mucin Secretogogues for the Treatment of Dry Eye Syndrome in Office Workers.
Topics: Adult; Alanine; Conjunctiva; Dry Eye Syndromes; Female; Humans; Male; Middle Aged; Occupational Diseases; Polyphosphates; Prospective Studies; Quality of Life; Quinolones; Sclera; Secretagogues; Surveys and Questionnaires; Treatment Outcome; Uracil Nucleotides | 2017 |
Randomized Controlled Trial Comparing the Effects of Vonoprazan Plus Rebamipide and Esomeprazole Plus Rebamipide on Gastric Ulcer Healing Induced by Endoscopic Submucosal Dissection.
Topics: Aged; Aged, 80 and over; Alanine; Anti-Ulcer Agents; Drug Therapy, Combination; Endoscopic Mucosal Resection; Esomeprazole; Female; Humans; Male; Middle Aged; Proton Pump Inhibitors; Pyrroles; Quinolones; Severity of Illness Index; Stomach Neoplasms; Stomach Ulcer; Sulfonamides; Wound Healing | 2019 |
The post hoc analysis comparing the severity grades of chemoradiotherapy-induced oral mucositis scored between the central and local assessors in a multicenter, randomized controlled trial of rebamipide for head and neck cancer.
Topics: Aged; Alanine; Chemoradiotherapy; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Placebos; Quinolones; Stomatitis | 2019 |
Efficacy and safety of the use of rebamipide in the scheme of triple eradication therapy of Helicobacter pylori infection: a prospective randomized comparative study.
Topics: Adult; Alanine; Amoxicillin; Anti-Infective Agents; Anti-Ulcer Agents; Clarithromycin; Drug Administration Schedule; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Omeprazole; Peptic Ulcer; Prospective Studies; Quinolones; Treatment Outcome | 2018 |
A Multicenter, Randomized, Controlled Trial of Rebamipide Plus Lansoprazole for the Treatment of Postendoscopic Submucosal Dissection Ulcers.
Topics: Administration, Oral; Aged; Alanine; Anti-Ulcer Agents; Biopsy; Double-Blind Method; Drug Therapy, Combination; Endoscopic Mucosal Resection; Female; Gastric Mucosa; Gastroscopy; Humans; Lansoprazole; Male; Middle Aged; Prospective Studies; Quinolones; Stomach Ulcer; Time Factors; Treatment Outcome | 2019 |
Cytoprotective agent for peptic ulcer prevention in patients taking dual antiplatelet agents: A randomized, double-blind placebo-controlled trial.
Topics: Aged; Alanine; Anti-Ulcer Agents; Aspirin; Cilostazol; Clopidogrel; Cytoprotection; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Peptic Ulcer; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Quinolones; Thailand; Ticagrelor; Time Factors; Treatment Outcome | 2019 |
Comparison of the Efficacy of Polaprezinc Plus Proton Pump Inhibitor and Rebamipide Plus Proton Pump Inhibitor Treatments for Endoscopic Submucosal Dissection-induced Ulcers.
Topics: Alanine; Anti-Ulcer Agents; Carnosine; Drug Therapy, Combination; Endoscopic Mucosal Resection; Humans; Organometallic Compounds; Proton Pump Inhibitors; Quinolones; Stomach Neoplasms; Stomach Ulcer; Ulcer; Zinc Compounds | 2021 |
Assessment of mucin-related gene alterations following treatment with rebamipide ophthalmic suspension in Sjögren's syndrome-associated dry eyes.
Topics: Adult; Aged; Aged, 80 and over; Alanine; CA-125 Antigen; Female; Gene Expression Regulation; Humans; Male; Membrane Proteins; Middle Aged; Mucin 5AC; Ophthalmic Solutions; Prospective Studies; Proto-Oncogene Proteins c-ets; Quinolones; Sjogren's Syndrome | 2020 |
Efficacy and Safety of Rebamipide versus Its New Formulation, AD-203, in Patients with Erosive Gastritis: A Randomized, Double-Blind, Active Control, Noninferiority, Multicenter, Phase 3 Study.
Topics: Alanine; Double-Blind Method; Gastritis; Humans; Quinolones; Stomach Ulcer; Treatment Outcome | 2021 |
Rebamipide for the Improvement of Gastric Atrophy and Intestinal Metaplasia: A Prospective, Randomized, Pilot Study.
Topics: Alanine; Atrophy; Gastric Mucosa; Gastritis, Atrophic; Helicobacter Infections; Helicobacter pylori; Humans; Metaplasia; Pilot Projects; Prospective Studies; Quinolones; Stomach Neoplasms | 2022 |
The effect of rebamipide on non-steroidal anti-inflammatory drug-induced gastro-enteropathy: a multi-center, randomized pilot study.
Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Humans; Intestinal Diseases; Pilot Projects; Ulcer | 2022 |
Efficacy and safety of 1% and 2% rebamipide clear solution in dry eye disease: a multicenter randomized trial.
Topics: Adult; Alanine; Dry Eye Syndromes; Humans; Middle Aged; Ophthalmic Solutions; Quinolones; Tears | 2023 |
311 other study(ies) available for alanine and opc 12759
| Article | Year |
|---|---|
Antiulcer mechanism of action of rebamipide, a novel antiulcer compound, on diethyldithiocarbamate-induced antral gastric ulcers in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Cytochrome c Group; Ditiocarb; Gastric Mucosa; Lipid Peroxidation; Male; Microsomes, Liver; Neutrophils; Oxidation-Reduction; Quinolones; Rats; Rats, Inbred Strains; Stomach Ulcer | 1992 |
Therapeutic effects of oral rebamipide and in combination with cimetidine on experimental gastritis in rats.
Topics: Administration, Oral; Alanine; Animals; Anti-Ulcer Agents; Cimetidine; Disease Models, Animal; Drug Therapy, Combination; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Gastritis, Atrophic; Male; Quinolones; Rats; Rats, Wistar; Taurocholic Acid | 1992 |
Effect of rebamipide on mucus secretion by endogenous prostaglandin-independent mechanism in rat gastric mucosa.
Topics: Alanine; Animals; Anti-Ulcer Agents; Gastric Mucosa; Glycoproteins; Indomethacin; Male; Mucins; Mucus; Prostaglandins; Quinolones; Rats; Rats, Wistar | 1992 |
Effects of various mucosal protective drugs on diethyldithiocarbamate-induced antral ulcer in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Ditiocarb; Male; Pyloric Antrum; Quinolones; Rats; Rats, Inbred Strains; Stomach Ulcer; Superoxide Dismutase | 1991 |
Synthesis and antiulcer activity of optical isomers of 2-(4-chlorobenzoylamino)-3-[2(1H)-quinolinon-4-yl]propionic acid (rebamipide).
Topics: Alanine; Animals; Anti-Ulcer Agents; Male; Quinolones; Rats; Rats, Inbred Strains; Stereoisomerism | 1991 |
Effect of OPC-12759, a novel antiulcer agent, on chronic and acute experimental gastric ulcer, and gastric secretion in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Gastric Mucosa; Male; Perfusion; Quinolones; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Psychological | 1989 |
High-performance liquid chromatographic procedure for the determination of a new anti-gastric ulcer agent, 2-(4-chlorobenzoylamino)-3-[2(1H)-quinolinon-4-yl]propioni c acid, in human plasma and urine.
Topics: Alanine; Anti-Ulcer Agents; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Humans; Male; Quinolones; Spectrometry, Fluorescence | 1988 |
[Healing promoting effect of proamipide, a novel drug that increases gastric defense mechanisms, on acetic acid-induced gastric ulcers in the rat].
Topics: Acetates; Alanine; Animals; Anti-Ulcer Agents; Fibrosis; Gastric Mucosa; Granulation Tissue; Male; Quinolones; Rats; Rats, Inbred Strains; Recurrence; Regeneration; Stomach Ulcer; Time Factors | 1988 |
Gastric mucosal protection by OPC-12759, a novel antiulcer compound, in the rat.
Topics: Alanine; Animals; Anti-Ulcer Agents; Atropine; Cimetidine; Dinoprostone; Gastric Mucosa; Indomethacin; Injections, Intraperitoneal; Male; Prostaglandins E; Quinolines; Quinolones; Rats; Rats, Inbred Strains | 1987 |
Studies on 2(1H)-quinolinone derivatives as gastric antiulcer active agents. Synthesis and antiulcer activities of optically active alpha-amino acid derivatives of 2(1H)-quinolinone and oxindole.
Topics: Alanine; Animals; Anti-Ulcer Agents; Indoles; Quinolines; Quinolones; Rats; Stomach Ulcer; Structure-Activity Relationship | 1987 |
Preventive effect of rebamipide on gastric lesions induced by ischemia-reperfusion in the rat.
Topics: Alanine; Animals; Anti-Ulcer Agents; Chemotaxis, Leukocyte; Free Radical Scavengers; Gastric Mucosa; Hydroxyl Radical; Male; Malondialdehyde; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide Synthase; Peroxidase; Quinolones; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stimulation, Chemical; Stomach; Stomach Ulcer; Superoxide Dismutase; Superoxides; Zymosan | 1995 |
Rebamipide, novel prostaglandin-inducer accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer. Comparison with cimetidine.
Topics: Acetates; Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Cimetidine; Drug Therapy, Combination; Male; Prostaglandins; Quinolones; Rats; Rats, Wistar; Recurrence; Stomach Ulcer; Wound Healing | 1995 |
Active oxygen species in formation of acute gastric mucosal lesions induced by thermal injury in rats.
Topics: Acute Disease; Alanine; Analysis of Variance; Animals; Anti-Ulcer Agents; Burns; Drug Evaluation, Preclinical; Gastric Mucosa; Leukocytes; Luminescent Measurements; Male; Quinolones; Rats; Rats, Wistar; Reactive Oxygen Species; Stomach Ulcer; Time Factors | 1995 |
Hydroxyl radical scavenging by rebamipide and related compounds: electron paramagnetic resonance study.
Topics: Alanine; Binding, Competitive; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxyl Radical; Kinetics; Methylation; Quinolines; Quinolones; Spin Labels | 1995 |
Rebamipide, a novel antiulcer agent, attenuates Helicobacter pylori induced gastric mucosal cell injury associated with neutrophil derived oxidants.
Topics: Alanine; Animals; Anti-Ulcer Agents; Cells, Cultured; Dose-Response Relationship, Drug; Epithelium; Gastric Mucosa; Helicobacter pylori; Luminescent Measurements; Neutrophils; Oxidants; Quinolones; Rabbits; Urease | 1994 |
Protective effect of rebamipide against hydrogen peroxide-induced hemorrhagic mucosal lesions in rat stomach.
Topics: Alanine; Animals; Gastric Mucosa; Gastrointestinal Hemorrhage; Glutathione; Glutathione Peroxidase; Hydrogen Peroxide; Male; Quinolones; Rats; Rats, Wistar; Stomach Diseases; Superoxide Dismutase | 1994 |
Effect of rebamipide on lipid peroxidation and gastric mucosal injury induced by indometacin in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Free Radicals; Gastric Mucosa; Indomethacin; Lipid Peroxidation; Male; Quinolones; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Stomach Ulcer; Thiobarbituric Acid Reactive Substances | 1993 |
Free radical scavenging activity of the novel anti-ulcer agent rebamipide studied by electron spin resonance.
Topics: Alanine; Anti-Ulcer Agents; Bepridil; Biphenyl Compounds; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Humans; In Vitro Techniques; Neutrophils; Picrates; Quinolones; Superoxides; Zymosan | 1993 |
Stimulation of prostaglandin biosynthesis mediates gastroprotective effect of rebamipide in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Alanine; Animals; Anti-Ulcer Agents; Dinoprostone; Dose-Response Relationship, Drug; Gastric Juice; In Vitro Techniques; Indomethacin; Male; Prostaglandins; Quinolones; Rats; Rats, Wistar; Thromboxane B2 | 1993 |
Rebamipide protects against activation of neutrophils by Helicobacter pylori.
Topics: Alanine; Anti-Ulcer Agents; CD18 Antigens; Cell Adhesion; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Flow Cytometry; Helicobacter pylori; Humans; In Vitro Techniques; Neutrophil Activation; Neutrophils; Quinolones; Reactive Oxygen Species | 1996 |
The effect of rebamipide on gastric xanthine oxidase activity and type conversion in ethanol-treated rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Enzyme Inhibitors; Ethanol; Free Radicals; Lipid Peroxidation; Male; Peptic Ulcer Hemorrhage; Quinolones; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stomach Ulcer; Xanthine Oxidase | 1996 |
Rebamipide ameliorates hepatic dysfunction induced by ischemia/reperfusion in rats.
Topics: Alanine; Alanine Transaminase; Allopurinol; Animals; Bile; Enzyme Inhibitors; Free Radical Scavengers; Lipid Peroxidation; Liver Diseases; Male; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Organ Size; Quinolones; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Vitamin E; Xanthine Oxidase | 1995 |
Effects of rebamipide on gastric cell damage by Helicobacter pylori-stimulated human neutrophils.
Topics: Alanine; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Helicobacter pylori; Humans; Neutrophils; Peptic Ulcer; Quinolones; Rabbits; Stomach; Time Factors | 1995 |
Impairment of antioxidants in colonic epithelial cells isolated from trinitrobenzene sulphonic acid-induced colitis rats. Protective effect of rebamipide.
Topics: Alanine; Analysis of Variance; Animals; Anti-Ulcer Agents; Antioxidants; Colitis; Culture Techniques; Disease Models, Animal; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Intestinal Mucosa; Male; Quinolones; Random Allocation; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid | 1996 |
Protective effect of taurine on indomethacin-induced gastric mucosal injury.
Topics: Adult; Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Gastric Mucosa; Humans; Indomethacin; Lipid Peroxidation; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Quinolones; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Taurine; Thiobarbituric Acid Reactive Substances; Umbilical Veins | 1996 |
Effects of rebamipide on bile acid-induced inhibition of gastric epithelial repair in a rabbit cell culture model.
Topics: Actins; Alanine; Animals; Anti-Ulcer Agents; Bromodeoxyuridine; Cell Division; Cell Movement; Cells, Cultured; Deoxycholic Acid; Disease Models, Animal; Epithelial Cells; Epithelium; Gastric Mucosa; Male; Quinolones; Rabbits; Staining and Labeling; Stomach Diseases | 1996 |
Role of rebamipide on induction of heat-shock proteins and protection against reactive oxygen metabolite-mediated cell damage in cultured gastric mucosal cells.
Topics: Alanine; Animals; Anti-Ulcer Agents; Catalase; Cell Death; Cells, Cultured; Free Radical Scavengers; Gastric Mucosa; HSP70 Heat-Shock Proteins; Hydroxyl Radical; Hypoxanthine; Lipid Peroxidation; Quinolones; Rabbits; Reactive Oxygen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase | 1997 |
Rebamipide attenuates indomethacin-induced gastric mucosal lesion formation by inhibiting activation of leukocytes in rats.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cimetidine; Gastric Mucosa; Glycine; Humans; In Vitro Techniques; Indomethacin; Leukocyte Elastase; Male; Neutrophil Activation; Neutrophils; Peroxidase; Quinolones; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Sulfonamides | 1997 |
Preventive effect of rebamipide on gastric mucosal cell damage evoked by activation of formyl-methionyl-leucyl-phenylalanine receptors of rabbit neutrophils.
Topics: Alanine; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Gastric Mucosa; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Quinolones; Rabbits; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Sodium Fluoride; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
Effects of rebamipide in a model of experimental diabetes and on the synthesis of transforming growth factor-beta and fibronectin, and lipid peroxidation induced by high glucose in cultured mesangial cells.
Topics: Alanine; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fibronectins; Glucose; Lipid Metabolism; Male; Quinolones; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta | 1997 |
[Protection of cultured mammalian cells by rebamipide].
Topics: Alanine; Animals; Anti-Ulcer Agents; Cells, Cultured; Cricetinae; Cricetulus; Free Radical Scavengers; Quinolones; Radiation-Protective Agents | 1997 |
Effects of rebamipide, a novel anti-ulcer agent, on gastric mucosal injury induced by platelet-activating factor in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Gastric Mucosa; Lipid Peroxides; Male; Peroxidase; Platelet Activating Factor; Quinolones; Rats; Rats, Wistar | 1997 |
Effect of rebamipide, a novel antiulcer agent, on Helicobacter pylori adhesion to gastric epithelial cells.
Topics: Alanine; Animals; Anti-Ulcer Agents; Bacterial Adhesion; Gastric Mucosa; Helicobacter pylori; Humans; Male; Quinolones; Rabbits; Tumor Cells, Cultured | 1998 |
Protective effect of rebamipide against ammonia-induced gastric mucosal lesions.
Topics: Alanine; Ammonia; Animals; Anti-Ulcer Agents; Antioxidants; Gastric Mucosa; Male; Prostaglandins; Quinolones; Rats; Rats, Wistar; Stomach Ulcer | 1998 |
Rebamipide treatment activates epidermal growth factor and its receptor expression in normal and ulcerated gastric mucosa in rats: one mechanism for its ulcer healing action?
Topics: Alanine; Animals; Anti-Ulcer Agents; Disease Models, Animal; Epidermal Growth Factor; ErbB Receptors; Fluorescent Antibody Technique; Gene Expression Regulation; Male; Quinolones; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 1998 |
Rebamipide prevented delay of wound repair induced by hydrogen peroxide and suppressed apoptosis of gastric epithelial cells in vitro.
Topics: Alanine; Animals; Antioxidants; Apoptosis; Cell Division; Epithelium; Gastric Mucosa; Hydrogen Peroxide; In Vitro Techniques; Oxidants; Quinolones; Rabbits; Wound Healing | 1998 |
Rebamipide protects against oxygen radical-mediated gastric mucosal injury in rats.
Topics: Alanine; Animals; Antioxidants; Free Radicals; Gastric Mucosa; Male; Oxygen; Quinolones; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1998 |
IFN-gamma-induced iNOS mRNA expression is inhibited by rebamipide in murine macrophage RAW264.7 cells.
Topics: Alanine; Animals; Antioxidants; Cell Line; Gene Expression Regulation, Enzymologic; Interferon-gamma; Macrophages; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Quinolones; RNA, Messenger | 1998 |
Protection by rebamipide against acetic acid-induced colitis in rats: relationship with its antioxidative activity.
Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Antioxidants; Colitis; Intestinal Mucosa; Lipid Peroxidation; Male; Neutrophils; Quinolones; Rats; Rats, Wistar; Reactive Oxygen Species | 1998 |
Rebamipide prevents indomethacin-induced gastric mucosal lesion formation by inhibiting activation of neutrophils in rats.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Calcium; Gastric Mucosa; Indomethacin; Leukocyte Elastase; Male; Neutrophils; Peroxidase; Quinolones; Rats; Rats, Wistar; Stomach Ulcer | 1998 |
Changes in colonic inflammation induced by dextran sulfate sodium (DSS) during short- and long-term administration of rebamipide.
Topics: Acute Disease; Alanine; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Anticoagulants; Chronic Disease; Colitis; Colonoscopy; Dextran Sulfate; Drug Administration Schedule; Leukocyte Count; Male; Peroxidase; Quinolones; Rats; Rats, Sprague-Dawley | 1998 |
Rebamipide attenuates gastric microcirculatory disturbances in the early period after thermal injury in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Burns; Gastric Mucosa; Leukocytes; Male; Microcirculation; Quinolones; Rats; Rats, Wistar; Reactive Oxygen Species | 1998 |
Effect of rebamipide on liver damage and increased tumor necrosis factor in a rat model of endotoxin shock.
Topics: Alanine; Animals; Disease Models, Animal; Enzyme Inhibitors; Escherichia coli; Lipopolysaccharides; Liver; Male; Peroxidase; Quinolones; Rats; Rats, Sprague-Dawley; Shock, Septic; Tumor Necrosis Factor-alpha | 1998 |
Effects of rebamipide on production of several cytokines by human peripheral blood mononuclear cells.
Topics: Alanine; Anti-Ulcer Agents; Cytokines; Escherichia coli; Helicobacter pylori; Humans; Lipopolysaccharides; Monocytes; Quinolones; T-Lymphocytes, Helper-Inducer | 1998 |
Nonopsonic activation of neutrophils by Helicobacter pylori is inhibited by rebamipide.
Topics: Alanine; Anti-Ulcer Agents; Flow Cytometry; Helicobacter pylori; Humans; Luminescent Measurements; Neutrophil Activation; Neutrophils; Opsonin Proteins; Quinolones | 1998 |
Molecular analysis of suppression of interleukin-8 production by rebamipide in Helicobacter pylori-stimulated gastric cancer cell lines.
Topics: Alanine; Anti-Ulcer Agents; Blotting, Northern; DNA Primers; Gene Expression Regulation, Neoplastic; Helicobacter pylori; Humans; Interleukin-8; Quinolones; RNA, Messenger; Stomach Neoplasms; Tumor Cells, Cultured | 1998 |
Effect of rebamipide on H. pylori-associated gastric mucosal injury in Mongolian gerbils.
Topics: Alanine; Animals; Anti-Ulcer Agents; Gastric Mucosa; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Male; Quinolones; Stomach Ulcer | 1998 |
Inhibitory effects of rebamipide on ENNG-induced duodenal carcinogenesis in mice: a possible strategy for chemoprevention of gastrointestinal cancers.
Topics: Alanine; Animals; Antineoplastic Agents; Carcinogens; Disease Models, Animal; Dose-Response Relationship, Drug; Duodenal Neoplasms; Male; Methylnitronitrosoguanidine; Mice; Mice, Inbred C57BL; Quinolones | 1998 |
Effect of rebamipide on the glycosaminoglycan content of the ulcerated rat stomach.
Topics: Alanine; Analysis of Variance; Animals; Anti-Ulcer Agents; Chromatography, Gel; Glycosaminoglycans; Hexosamines; Histamine; Male; Quinolones; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Time Factors; Uronic Acids | 1998 |
Inhibitory effect of rebamipide on the neutrophil adherence stimulated by conditioned media from Helicobacter pylori-infected gastric epithelial cells.
Topics: Alanine; Anti-Ulcer Agents; Antibodies; Cell Adhesion; Culture Media, Conditioned; Cytokines; Epithelial Cells; Gastric Mucosa; Helicobacter pylori; Humans; Interleukin-8; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polymerase Chain Reaction; Quinolones; RNA, Messenger; Tumor Cells, Cultured | 1999 |
Therapeutic effect of rebamipide on ammonia-induced gastric mucosal hemorrhagic lesion in rats.
Topics: Alanine; Ammonia; Animals; Anti-Ulcer Agents; Enzyme Inhibitors; Gastric Mucosa; Gastrointestinal Hemorrhage; Lipid Peroxidation; Lipid Peroxides; Male; Quinolones; Rats; Rats, Sprague-Dawley; Xanthine Dehydrogenase; Xanthine Oxidase | 1998 |
Indomethacin-induced gastric antral damage in hamsters: are neutrophils involved?
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cricetinae; Gastric Mucosa; Indomethacin; Male; Mesocricetus; Methotrexate; Mice; Neutrophils; Peroxidase; Pyloric Antrum; Quinolones | 1999 |
Influence of rebamipide on indometacin-induced gastric hemorrhage in rats under restraint stress.
Topics: Acute Disease; Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Catalase; Cimetidine; Diterpenes; Gastritis; Gastrointestinal Hemorrhage; Indomethacin; Leukocyte Count; Male; Neutrophils; Omeprazole; Perfusion; Quinolones; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological; Superoxide Dismutase | 1999 |
A novel effect of rebamipide: generation of [Ca(2+)](i) oscillations through activation of CCK(1) receptors in rat pancreatic acinar cells.
Topics: Alanine; Animals; Anti-Ulcer Agents; Atropine; Benzodiazepinones; Calcium; Devazepide; Fluorescent Dyes; Fura-2; In Vitro Techniques; Male; Muscarinic Antagonists; Pancreas; Phenylurea Compounds; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin | 2000 |
Inhibition of lipid peroxidation, NF-kappaB activation and IL-8 production by rebamipide in Helicobacter pylori-stimulated gastric epithelial cells.
Topics: Alanine; Anti-Ulcer Agents; Cells, Cultured; Cytokines; Epithelial Cells; Free Radical Scavengers; Gastric Mucosa; Helicobacter pylori; Humans; Interleukin-8; Lipid Peroxidation; NF-kappa B; Quinolones | 2000 |
The effect of rebamipide on cisplatin-induced nephrotoxicity in rats.
Topics: Alanine; Animals; Antineoplastic Agents; Cisplatin; Free Radical Scavengers; Glutathione; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Quinolones; Rats; Rats, Wistar | 2000 |
Positive effect of rebamipide on gastric permeability in mice after eradication of Helicobacter felis.
Topics: Alanine; Animals; Anti-Ulcer Agents; Disease Models, Animal; Gastric Mucosa; Helicobacter; Helicobacter Infections; Mice; Mice, Inbred C57BL; Permeability; Quinolones | 2000 |
Effect of rebamipide on prostaglandin EP4 receptor gene expression in rat gastric mucosa.
Topics: Alanine; Animals; Anti-Ulcer Agents; Cyclic AMP; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Gastric Mucosa; Gene Expression; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Quinolones; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger | 2000 |
Anti-inflammatory effect of rebamipide enema on proctitis type ulcerative colitis: a novel therapeutic alternative.
Topics: Adult; Alanine; Anti-Ulcer Agents; Colitis, Ulcerative; Enema; Female; Humans; Proctitis; Quinolones | 2000 |
Rebamipide inhibits neutrophil adhesion to hypoxia/reoxygenation-stimulated endothelial cells via nuclear factor-kappaB-dependent pathway.
Topics: Alanine; Antibodies, Monoclonal; Antioxidants; Cell Adhesion; Cell Hypoxia; Cells, Cultured; E-Selectin; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Neutrophils; NF-kappa B; P-Selectin; Quinolones; Umbilical Veins | 2000 |
Combined effect of rebamipide and ecabet sodium on Helicobacter pylori adhesion to gastric epithelial cells.
Topics: Abietanes; Alanine; Anti-Ulcer Agents; Bacterial Adhesion; Cell Line; Diterpenes; Drug Synergism; Epithelial Cells; Helicobacter pylori; Humans; Quinolones; Stomach Ulcer | 2000 |
Suppressive effect of rebamipide, an antiulcer agent, against activation of human neutrophils exposed to formyl-methionyl-leucyl-phenylalanine.
Topics: Alanine; Alkaline Phosphatase; Anti-Ulcer Agents; Calcium; Cell Movement; Chemotactic Factors; Chemotaxis; Flow Cytometry; Humans; In Vitro Techniques; Indicators and Reagents; Macrophage Activation; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Quinolones; Receptors, IgG; Secretory Vesicles; Signal Transduction; Up-Regulation | 2000 |
Rebamipide, an antiulcer drug, prevents DSS-induced colitis formation in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Interleukin-1; Interleukin-8; Male; Peroxidase; Quinolones; Rats; Rats, Wistar | 2000 |
Induction of cyclooxygenase-2 in rat gastric mucosa by rebamipide, a mucoprotective agent.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Gastric Mucosa; Hydrochloric Acid; Isoenzymes; Male; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Quinolones; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Sulfonamides; Up-Regulation | 2000 |
OPC-compounds prevent oxidant-induced carbonylation and depolymerization of the F-actin cytoskeleton and intestinal barrier hyperpermeability.
Topics: Actins; Alanine; Antioxidants; Blotting, Western; Caco-2 Cells; Cytoskeleton; Fluorescent Dyes; Humans; Immunoblotting; Intestinal Mucosa; Microscopy, Fluorescence; Oxidants; Oxidation-Reduction; Permeability; Quinolones; Reactive Oxygen Species; Thiazoles | 2001 |
Rebamipide suppresses formyl-methionyl-leucyl-phenylalanine (fMLP)-induced superoxide production by inhibiting fMLP-receptor binding in human neutrophils.
Topics: Alanine; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Helicobacter pylori; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Quinolones; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Superoxides | 2001 |
Rebamipide prevents periarterial blood-induced vasospasm in the rat femoral artery model.
Topics: Alanine; Animals; Aorta, Thoracic; Enzyme Inhibitors; Femoral Artery; Granulocytes; Intercellular Adhesion Molecule-1; Macrophages; Male; Muscle Contraction; Muscle, Smooth, Vascular; Quinolones; Rats; Rats, Sprague-Dawley; Superoxides; Transfusion Reaction; Xanthine Oxidase | 2001 |
Rebamipide inhibits ceramide-induced interleukin-8 production in Kato III human gastric cancer cells.
Topics: Alanine; Anti-Ulcer Agents; Blotting, Northern; Blotting, Western; Ceramides; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Helicobacter Infections; Helicobacter pylori; Humans; Interleukin-8; Mitogen-Activated Protein Kinases; NF-kappa B; Quinolones; Signal Transduction; Stomach Neoplasms; Tumor Cells, Cultured | 2001 |
Alterations of epithelial permeability by Helicobacter and IL-1beta in vitro: protective effect of rebamipide.
Topics: Alanine; Anti-Ulcer Agents; Cell Membrane Permeability; Epithelial Cells; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Interferon-gamma; Interleukin-1; Quinolones; Tumor Cells, Cultured | 2001 |
The antioxidant effect of rebamipide on oxygen free radical production by H. pylori-activated human neutrophils: in comparison with N-acetylcysteine, ascorbic acid and glutathione.
Topics: Acetylcysteine; Alanine; Antioxidants; Ascorbic Acid; Glutathione; Helicobacter pylori; Humans; Luminescent Measurements; Neutrophil Activation; Neutrophils; Pyrogallol; Quinolones; Reactive Oxygen Species | 2001 |
The inhibitory mechanism of rebamipide on the mediator release in the guinea pig lung mast cells activated with specific antigen-antibody reactions.
Topics: Alanine; Animals; Antigen-Antibody Reactions; Calcimycin; Calcium; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Female; Guinea Pigs; Histamine Release; Inflammation Mediators; Leukotriene D4; Leukotrienes; Lung; Mast Cells; Phospholipase D; Phospholipases A; Protein Kinase C; Quinolones | 2001 |
Protective effect of rebamipide on indomethacin-induced intestinal damage in rats.
Topics: Alanine; Ampicillin; Animals; Anti-Ulcer Agents; Bacterial Translocation; Catalase; Dose-Response Relationship, Drug; Enterobacteriaceae; Enzyme Inhibitors; Indomethacin; Intestinal Diseases; Lipid Peroxidation; Male; Nitric Oxide Synthase; Peroxidase; Quinolones; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2001 |
Effect of rebamipide on cell death induced by combined treatment of mild heat shock and quercetin in RGM-1 cells: a role for HSP70 induction.
Topics: Alanine; Animals; Anti-Ulcer Agents; Apoptosis; Cell Survival; Cells, Cultured; DNA Fragmentation; Drug Interactions; Gastric Mucosa; Hot Temperature; HSP70 Heat-Shock Proteins; Quercetin; Quinolones; Rats | 2002 |
[A case of rebamipide-induced pneumonitis].
Topics: Aged; Alanine; Anti-Ulcer Agents; Humans; Male; Pneumonia; Quinolones | 2002 |
Modulatory effects of plasma and colonic milieu of patients with ulcerative colitis on neutrophil reactive oxygen species production in presence of a novel antioxidant, rebamipide.
Topics: Alanine; Antioxidants; Colitis, Ulcerative; Humans; Neutrophils; Quinolones; Reactive Oxygen Species; Respiratory Burst | 2002 |
Local gastric and serum concentrations of rebamipide following oral ingestion in healthy volunteers.
Topics: Administration, Oral; Adult; Alanine; Anti-Ulcer Agents; Chromatography, High Pressure Liquid; Gastric Mucosa; Humans; Male; Mucus; Quinolones | 2002 |
Rebamipide prevents delay of acetic acid-induced gastric ulcer healing caused by Helicobacter pylori infection in Mongolian gerbils.
Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Apoptosis; Cell Division; Epithelium; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Male; Neutrophil Infiltration; Quinolones; Stomach Ulcer; Wound Healing | 2002 |
Involvement of cytochrome P450 in the metabolism of rebamipide by the human liver.
Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antibodies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Quinolones; Recombinant Proteins; Troleandomycin | 2002 |
Combinatorial use of sodium laurate with taurine or L-glutamine enhances colonic absorption of rebamipide, poorly absorbable antiulcer drug, without any serious histopathological mucosal damages.
Topics: Adjuvants, Pharmaceutic; Administration, Oral; Alanine; Amino Acids; Animals; Anti-Ulcer Agents; Biological Availability; Colon; Cytoprotection; Glutamine; Intestinal Absorption; Intestinal Mucosa; Lauric Acids; Male; Quinolones; Rats; Rats, Sprague-Dawley; Taurine | 2003 |
Effect of rebamipide on acetic acid-induced gastric ulcer in rats: involvement of hepatocyte growth factor.
Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Cyclooxygenase 2; Gastric Mucosa; Glyceraldehyde-3-Phosphate Dehydrogenases; Hepatocyte Growth Factor; Immunohistochemistry; Isoenzymes; Male; Proliferating Cell Nuclear Antigen; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-met; Quinolones; Rats; Rats, Inbred F344; Receptors, Prostaglandin E; Reverse Transcriptase Polymerase Chain Reaction; Stomach Ulcer | 2003 |
Characteristics of attenuating effects of rebamipide, an anti-ulcer agent, on oxidative burst of human neutrophils.
Topics: Adult; Alanine; Anti-Ulcer Agents; Cimetidine; Depression, Chemical; Dose-Response Relationship, Drug; Histamine H2 Antagonists; Humans; In Vitro Techniques; Luminescent Measurements; Male; Neutrophils; Quinolones; Respiratory Burst | 2003 |
Cytoprotective effects of rebamipide and carteolol hydrochloride against ultraviolet B-induced corneal damage in mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adrenergic beta-Antagonists; Alanine; Animals; Anti-Ulcer Agents; Carteolol; Cornea; Corneal Diseases; Cytoprotection; Deoxyguanosine; Electron Spin Resonance Spectroscopy; Immunoenzyme Techniques; Male; Mice; Mice, Inbred BALB C; Quinolones; Radiation Injuries, Experimental; Ultraviolet Rays | 2003 |
Comparison of the effects of rebamipide with those of cimetidine on chronic gastritis associated with Helicobacter pylori in Mongolian gerbils.
Topics: Alanine; Animals; Anti-Ulcer Agents; Chemokines; Cimetidine; Gastrins; Gastritis; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Male; Neutrophils; Peroxidase; Quinolones; Tumor Necrosis Factor-alpha | 2003 |
Effect of long-term administration of rebamipide on Helicobacter pylori infection in mice.
Topics: Alanine; Animals; Anti-Ulcer Agents; Apoptosis; Blotting, Western; Cytokines; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Immunohistochemistry; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; NF-kappa B; Protein Binding; Proteins; Quinolones; RNA, Messenger | 2003 |
The effect of rebamipide on the expression of proinflammatory mediators and apoptosis in human neutrophils by Helicobacter pylori water-soluble surface proteins.
Topics: Alanine; Anti-Ulcer Agents; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cyclooxygenase 2; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Helicobacter pylori; Humans; Isoenzymes; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Neutrophils; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Quinolones; Radioimmunoassay; RNA, Messenger; Up-Regulation | 2003 |
The effect of rebamipide on Helicobacter pylori extract-mediated changes of gene expression in gastric epithelial cells.
Topics: Alanine; Anti-Ulcer Agents; Chemokine CCL5; Chemokine CXCL2; Down-Regulation; Epithelial Cells; Fibroblast Growth Factor 2; Gastric Mucosa; Gene Expression; Helicobacter pylori; Humans; Monokines; NF-kappa B; Oligonucleotide Array Sequence Analysis; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Tumor Cells, Cultured; Up-Regulation | 2003 |
Rebamipide binds to iNOS-positive cells in acetic acid-treated but not in ethanol-treated rat gastric mucosa.
Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Binding Sites; Ethanol; Gastric Mucosa; Indicators and Reagents; Models, Biological; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Quinolones; Rats; Solvents; Stomach Ulcer | 2003 |
The specific expression of hypoxia inducible factor-1alpha in human gastric mucosa induced by nonsteroidal anti-inflammatory drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Female; Gastric Mucosa; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Male; Middle Aged; Quinolones; Transcription Factors | 2003 |
Interaction of leptin with gastric myofibroblast transdifferentiation in Helicobacter pylori-infected Mongolian gerbils: the effect of rebamipide.
Topics: Alanine; Animals; Anti-Ulcer Agents; Autoradiography; Cell Differentiation; Fibroblasts; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Immunohistochemistry; Leptin; Quinolones | 2003 |
Expression of midkine and receptor-like protein tyrosine phosphatase (RPTP)-beta genes in the rat stomach and the influence of rebamipide.
Topics: Alanine; Animals; Anti-Ulcer Agents; Blotting, Northern; Carrier Proteins; Cells, Cultured; Cytokines; Gastric Mucosa; Male; Midkine; Nerve Tissue Proteins; Protein Tyrosine Phosphatases; Quinolones; Rats; Rats, Wistar; Receptor-Like Protein Tyrosine Phosphatases, Class 5; Reverse Transcriptase Polymerase Chain Reaction; RNA | 2003 |
Effect of rebamipide on prostaglandin receptors-mediated increase of inflammatory cytokine production by macrophages.
Topics: Alanine; Anti-Ulcer Agents; Cyclic AMP; Cytokines; Endothelial Growth Factors; Humans; Intercellular Signaling Peptides and Proteins; Interleukins; Lymphokines; Macrophages; Quinolones; Receptors, Prostaglandin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
Gastric restitution is inhibited by dexamethasone, which is reversed by hepatocyte growth factor and rebamipide.
Topics: Alanine; Anti-Inflammatory Agents; Anti-Ulcer Agents; Cells, Cultured; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Fibroblasts; Gastric Mucosa; Hepatocyte Growth Factor; Humans; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Quinolones; RNA, Messenger | 2003 |
The protective effect of rebamipide on paracellular permeability of rat gastric epithelial cells.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cyclooxygenase Inhibitors; Dinoprostone; Epithelial Cells; Gastric Mucosa; Indomethacin; Nitrobenzenes; Permeability; Quinolones; Rats; Sulfonamides | 2003 |
Effects of antioxidative agents on apoptosis induced by ischaemia-reperfusion in rat intestinal mucosa.
Topics: Alanine; Animals; Anti-Ulcer Agents; Antioxidants; Apoptosis; Dimethyl Sulfoxide; Free Radical Scavengers; Glutathione; Immunohistochemistry; Intestinal Mucosa; Male; Quinolones; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2003 |
Gastric Helicobacter infection inhibits development of oral tolerance to food antigens in mice.
Topics: Administration, Oral; Alanine; Anaphylaxis; Animals; Antigen Presentation; Antigens; Chickens; Female; Gastritis; Helicobacter Infections; Immune Tolerance; Immunity, Mucosal; Immunoglobulin E; Immunoglobulin G; In Vitro Techniques; Intestines; Mice; Mice, Inbred C3H; Muramidase; Ovalbumin; Quinolones; T-Lymphocytes | 2003 |
Free radical scavenger effect of rebamipide in sperm processing and cryopreservation.
Topics: Alanine; Antioxidants; Cell Membrane; Cell Survival; Cryopreservation; Free Radical Scavengers; Humans; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; Peroxidases; Quinolones; Reactive Oxygen Species; Semen Preservation; Sperm Motility; Spermatozoa | 2003 |
Rebamipide activates genes encoding angiogenic growth factors and Cox2 and stimulates angiogenesis: a key to its ulcer healing action?
Topics: Alanine; Animals; Anti-Ulcer Agents; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cyclooxygenase 2; Endothelium, Vascular; Gastric Mucosa; Gene Expression Regulation; Growth Substances; Isoenzymes; Microcirculation; Neovascularization, Physiologic; Prostaglandin-Endoperoxide Synthases; Quinolones; Rats; RNA, Messenger; Stomach | 2004 |
Preventive effect of the flavonoid, wogonin, against ethanol-induced gastric mucosal damage in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Apoptosis; Arachidonic Acid; Cyclooxygenase 2; Cytoprotection; Drugs, Chinese Herbal; Ethanol; Flavanones; Gastric Mucosa; Gastritis; HSP70 Heat-Shock Proteins; Hydroxyeicosatetraenoic Acids; Isoenzymes; Male; Prostaglandin-Endoperoxide Synthases; Quinolones; Random Allocation; Rats; Rats, Sprague-Dawley | 2004 |
Rebamipide increases the amount of mucin-like substances on the conjunctiva and cornea in the N-acetylcysteine-treated in vivo model.
Topics: Acetylcysteine; Alanine; Alcian Blue; Animals; Anti-Ulcer Agents; Conjunctiva; Cornea; Female; Models, Biological; Mucins; Ophthalmic Solutions; Quinolones; Rabbits; Rose Bengal; Wound Healing | 2004 |
Mechanism of hydroxyl radical scavenging by rebamipide: identification of mono-hydroxylated rebamipide as a major reaction product.
Topics: Alanine; Anti-Ulcer Agents; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Quinolones; Spin Labels; Ultraviolet Rays | 2004 |
Development of suppository formulation safely improving rectal absorption of rebamipide, a poorly absorbable drug, by utilizing sodium laurate and taurine.
Topics: Alanine; Animals; Area Under Curve; Biological Availability; Chemistry, Pharmaceutical; Intestinal Absorption; Intestinal Mucosa; Lauric Acids; Male; Quinolones; Rats; Rats, Inbred Strains; Solubility; Suppositories; Taurine; Triglycerides | 2004 |
Oral absorption and pharmacokinetics of rebamipide and rebamipide lysinate in rats.
Topics: Administration, Oral; Alanine; Animals; Anti-Ulcer Agents; Area Under Curve; Biological Availability; Drug Evaluation, Preclinical; Half-Life; Hydrogen-Ion Concentration; Injections, Intravenous; Male; Quinolones; Rats; Rats, Sprague-Dawley; Solubility; Water | 2004 |
Pharmacological characterization of rebamipide: its cholecystokinin CCK1 receptor binding profile and effects on Ca2+ mobilization and amylase release in rat pancreatic acinar cells.
Topics: Alanine; Amylases; Animals; Antioxidants; Binding, Competitive; Calcium; Cells, Cultured; Cholecystokinin; Dose-Response Relationship, Drug; Iodine Radioisotopes; Kinetics; Pancreas; Quinolones; Rats; Receptor, Cholecystokinin A; Sincalide; Succinimides | 2004 |
Protective effect of intra-rectal administration of rebamipide on dextran sulfate sodium-induced rat colitis.
Topics: Administration, Rectal; Alanine; Animals; Anti-Ulcer Agents; Anticoagulants; Colitis; Dextran Sulfate; Disease Models, Animal; Male; Quinolones; Rats; Rats, Wistar | 2004 |
Rebamipide inhibits gastric cancer growth by targeting survivin and Aurora-B.
Topics: Alanine; Aurora Kinase B; Aurora Kinases; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Delivery Systems; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Neoplasm Proteins; Protein Serine-Threonine Kinases; Quinolones; Stomach Neoplasms; Survivin | 2005 |
The inhibitory effects of rebamipide on cigarette smoke-induced airway mucin production.
Topics: Alanine; Animals; Antioxidants; Cell Line, Tumor; ErbB Receptors; Male; Mucin 5AC; Mucins; Quinolones; Rats; Respiratory Mucosa; Smoking; Tumor Necrosis Factor-alpha | 2006 |
COX-1 and COX-2 conversely promote and suppress ischemia-reperfusion gastric injury in mice.
Topics: Alanine; Animals; Blotting, Western; Celiac Artery; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Gastric Mucosa; Intercellular Adhesion Molecule-1; Laser-Doppler Flowmetry; Ligation; Membrane Proteins; Mice; Mice, Inbred ICR; Nitrobenzenes; Peroxidase; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Quinolones; Regional Blood Flow; Reperfusion Injury; Sulfonamides; Thiobarbituric Acid Reactive Substances | 2005 |
Rebamipide, a gastro-protective drug, inhibits indomethacin-induced apoptosis in cultured rat gastric mucosal cells: association with the inhibition of growth arrest and DNA damage-induced 45 alpha expression.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Apoptosis; Cell Culture Techniques; Cell Cycle Proteins; DNA Damage; Dose-Response Relationship, Drug; Down-Regulation; Gastric Mucosa; Gene Expression Profiling; Indomethacin; Nuclear Proteins; Oligonucleotide Probes; Polymerase Chain Reaction; Quinolones; Rats | 2005 |
Direct autoradiographic evidence that rebamipide interacts with neutrophils in dextran sulfate sodium induced colitis in rats.
Topics: Administration, Oral; Alanine; Animals; Anti-Ulcer Agents; Colitis; Dextran Sulfate; Disease Models, Animal; Goblet Cells; Indicators and Reagents; Male; Neutrophils; Quinolones; Rats; Rats, Wistar | 2005 |
Rebamipide enema is effective for treatment of experimental dextran sulfate sodium induced colitis in rats.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Enema; Indicators and Reagents; Male; Mesalamine; Quinolones; Rats; Rats, Sprague-Dawley | 2005 |
Rebamipide decreases the susceptibility of gastric mucosa to acid-induced injury in rats by inhibiting neutrophil activation.
Topics: Alanine; Animals; Anti-Ulcer Agents; Capillary Permeability; Gastric Acid; Gastric Mucosa; Male; Neutrophil Activation; Quinolones; Rats; Rats, Wistar; Regional Blood Flow | 2005 |
Rebamipide reduces delay in gastric ulcer healing in cyclooxygenase-2-deficient mice.
Topics: Alanine; Animals; Anti-Ulcer Agents; Cyclooxygenase 2; Gene Expression Profiling; Immunohistochemistry; Mice; Mice, Knockout; Neovascularization, Physiologic; Prostaglandin-Endoperoxide Synthases; Quinolones; Stomach Ulcer | 2005 |
Gastro-protective agent rebamipide induces cyclooxygenease-2 (COX-2) in gastric epithelial cells.
Topics: Alanine; Animals; Anti-Ulcer Agents; Blotting, Western; Cell Culture Techniques; Cyclooxygenase 2; Dose-Response Relationship, Drug; Gastric Mucosa; Gene Expression Regulation; Neutrophils; Prostaglandin-Endoperoxide Synthases; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Wound Healing | 2005 |
Rebamipide significantly inhibits indomethacin-induced mitochondrial damage, lipid peroxidation, and apoptosis in gastric epithelial RGM-1 cells.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Apoptosis; Cell Culture Techniques; Fluorescent Dyes; Gastric Mucosa; Indomethacin; Lipid Peroxidation; Membrane Potentials; Mitochondria; Quinolones; Rats; Rats, Wistar; Reactive Oxygen Species | 2005 |
Rebamipide reduces indomethacin-induced gastric injury in mice via down-regulation of ICAM-1 expression.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Down-Regulation; Female; Gastric Mucosa; Indomethacin; Intercellular Adhesion Molecule-1; Mice; Mice, Inbred ICR; Neutrophil Activation; Quinolones; Up-Regulation | 2005 |
Rebamipide reduces recurrence of experimental gastric ulcers: role of free radicals and neutrophils.
Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Free Radicals; Gastric Mucosa; Glutathione Peroxidase; Indicators and Reagents; Inflammation; Lipid Peroxidation; Neutrophil Infiltration; Peroxidase; Quinolones; Rats; Recurrence; Stomach Ulcer; Superoxide Dismutase | 2005 |
Prevention by rebamipide of acute reflux esophagitis in rats.
Topics: Acute Disease; Alanine; Animals; Anti-Ulcer Agents; Chemokine CXCL1; Chemokines, CXC; Esophagitis, Peptic; Esophagus; Intercellular Signaling Peptides and Proteins; Lipid Peroxidation; Male; Mucous Membrane; Neutrophil Activation; Peroxidase; Quinolones; Rats; Rats, Wistar; RNA, Messenger; Tumor Necrosis Factor-alpha | 2005 |
Radical scavengers: a remedy for presbyacusis. A pilot study.
Topics: Aged; Aged, 80 and over; Alanine; Ascorbic Acid; Audiometry; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Free Radical Scavengers; Humans; Male; Pilot Projects; Presbycusis; Probability; Quinolones; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2005 |
Novel oral formulation safely improving intestinal absorption of poorly absorbable drugs: utilization of polyamines and bile acids.
Topics: Adjuvants, Pharmaceutic; Administration, Oral; Alanine; Animals; Anti-Ulcer Agents; Area Under Curve; Biological Availability; Colon; Gastric Mucosa; Intestinal Absorption; Male; Quinolones; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Taurocholic Acid | 2006 |
Optimization of suppository preparation containing sodium laurate and taurine that can safely improve rectal absorption of rebamipide.
Topics: Administration, Rectal; Alanine; Animals; Biological Availability; Drug Carriers; Drug Compounding; Injections, Intravenous; Intestinal Absorption; Lauric Acids; Male; Quinolones; Rabbits; Rectum; Solubility; Suppositories; Taurine | 2006 |
Successful treatment of severe pouchitis with rebamipide refractory to antibiotics and corticosteroids: a case report.
Topics: Adrenal Cortex Hormones; Adult; Alanine; Anti-Bacterial Agents; Humans; Male; Metronidazole; Pouchitis; Quinolones | 2006 |
OPC-12759 increases proliferation of cultured rat conjunctival goblet cells.
Topics: Alanine; Animals; Anti-Ulcer Agents; Antioxidants; Cell Proliferation; Cells, Cultured; Coloring Agents; Conjunctiva; Goblet Cells; Histocytochemistry; Keratin-7; Keratins; Ki-67 Antigen; Male; Mucin 5AC; Mucins; Quinolones; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2006 |
Expression of intracellular adhesion molecule-1 linking superoxide to mobilization of granulocytes and macrophages after periarterial blood in rat femoral artery: effect of rebamipide.
Topics: Alanine; Animals; Antioxidants; Femoral Artery; Gene Expression; Granulocytes; Immunohistochemistry; In Vitro Techniques; Intercellular Adhesion Molecule-1; Macrophages; Male; Quinolones; Rats; Rats, Sprague-Dawley; Superoxides | 2000 |
Importance of bile acids for novel oral absorption system containing polyamines to improve intestinal absorption.
Topics: Alanine; Animals; Area Under Curve; Bile Acids and Salts; Bile Ducts; Biogenic Polyamines; Dogs; Intestinal Absorption; Ligation; Male; Quinolones; Rats; Rats, Sprague-Dawley; Spermine; Taurocholic Acid | 2006 |
[Case of drug-induced lung injury due to Rebamipide].
Topics: Aged; Alanine; Anti-Ulcer Agents; Biopsy; Diagnosis, Differential; Humans; Lung; Lung Diseases, Interstitial; Lymphocyte Activation; Male; Prednisolone; Quinolones; Treatment Outcome | 2006 |
Rebamipide inhibits gastric cancer cell growth.
Topics: Alanine; Anti-Ulcer Agents; Cell Proliferation; Cyclin-Dependent Kinases; Extracellular Signal-Regulated MAP Kinases; Humans; Immunohistochemistry; Phosphorylation; Quinolones; Signal Transduction; Smad Proteins; Stomach Neoplasms; Tumor Cells, Cultured | 2007 |
Effect of rebamipide on the colonic barrier in interleukin-10-deficient mice.
Topics: Alanine; Animals; Anti-Ulcer Agents; Colon; Disease Models, Animal; Female; Flow Cytometry; Helicobacter hepaticus; Helicobacter Infections; Interleukin-10; Intestinal Mucosa; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; Quinolones; Specific Pathogen-Free Organisms; T-Lymphocytes | 2007 |
Ileal cancer and erosions in the small intestine revealed by capsule endoscopy.
Topics: Adenocarcinoma; Adenoma; Aged, 80 and over; Alanine; Anti-Ulcer Agents; Capsule Endoscopy; Colonic Neoplasms; Endoscopy, Gastrointestinal; Enteritis; Gastrointestinal Hemorrhage; Humans; Ileal Neoplasms; Intestinal Polyps; Male; Neoplasm Staging; Neoplasms, Multiple Primary; Quinolones | 2007 |
Rebamipide contributes to reducing adverse effects of long-term administration of omeprazole in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Gastric Acid; Gastric Mucosa; Gastrins; Male; Omeprazole; Proton Pump Inhibitors; Quinolones; Rats; Rats, Wistar | 2007 |
Effect of rectal administration of rebamipide on dextran sulfate sodium-induced colitis: role of hepatocyte growth factor.
Topics: Administration, Rectal; Alanine; Animals; Anticoagulants; Apoptosis; Cell Proliferation; Colitis; Dextran Sulfate; Enzyme Inhibitors; Epithelial Cells; Female; Hepatocyte Growth Factor; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Quinolones | 2007 |
Up-to-date information on gastric mucosal lesions from long-term NSAID therapy in orthopedic outpatients: a study using logistic regression analysis.
Topics: Adult; Aged; Alanine; Anti-Ulcer Agents; Bone Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Endoscopy; Famotidine; Female; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Japan; Life Style; Male; Middle Aged; Outpatients; Peptic Ulcer; Prospective Studies; Quinolones; Risk Factors | 2007 |
Rebamipide, anti-gastric ulcer drug, up-regulates the induction of iNOS in proinflammatory cytokine-stimulated hepatocytes.
Topics: Alanine; Animals; Anti-Ulcer Agents; Cells, Cultured; Enzyme Induction; Hepatocytes; Humans; I-kappa B Proteins; Interleukin-1beta; Male; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Quinolones; Rats; Rats, Wistar; Receptors, Interleukin-1 Type I; Recombinant Proteins; Signal Transduction; Time Factors; Up-Regulation | 2008 |
Prophylactic effect of rebamipide against the irritative and healing impairment actions of alendronate in rat stomachs.
Topics: Acetic Acid; Administration, Oral; Alanine; Alendronate; Animals; Anti-Ulcer Agents; Blotting, Western; Drug Interactions; Epithelium; Fibroblast Growth Factor 2; Gastric Mucosa; Male; Membrane Potentials; Quinolones; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Stomach; Stomach Ulcer | 2007 |
Effective treatment with oral administration of rebamipide in a mouse model of Sjögren's syndrome.
Topics: Administration, Oral; Alanine; Animals; Anti-Inflammatory Agents; Autoantibodies; Cell Division; Cytokines; Disease Models, Animal; Female; Immunologic Factors; Lacrimal Apparatus; Mice; Mice, Mutant Strains; Quinolones; Salivary Glands; Sjogren's Syndrome; T-Lymphocytes; Thymectomy | 2008 |
Effect of OPC-12759 on EGF receptor activation, p44/p42 MAPK activity, and secretion in conjunctival goblet cells.
Topics: Alanine; Animals; Cells, Cultured; Conjunctiva; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Eye Proteins; Goblet Cells; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Quinolones; Rats; Rats, Sprague-Dawley | 2008 |
Prophylactic effect of rebamipide on aspirin-induced gastric lesions and disruption of tight junctional protein zonula occludens-1 distribution.
Topics: Alanine; Animals; Anti-Ulcer Agents; Aspirin; Cell Line; Cytoprotection; Fluorescent Antibody Technique; Gastric Mucosa; Male; Membrane Proteins; Permeability; Phosphoproteins; Quinolones; Rats; Rats, Sprague-Dawley; Zonula Occludens-1 Protein | 2008 |
Vulnerability of gastric mucosa to prednisolone in rats chronically exposed to cigarette smoke.
Topics: Alanine; Animals; Anti-Ulcer Agents; Blood Gas Analysis; Dinoprostone; Disease Models, Animal; Gastric Mucosa; Hypoxia-Inducible Factor 1, alpha Subunit; Lipid Peroxides; Male; Peptic Ulcer Hemorrhage; Prednisolone; Pulmonary Disease, Chronic Obstructive; Quinolones; Rats; Rats, Wistar; Respiratory Function Tests; Respiratory System; Smoking; Stomach Ulcer; Vascular Endothelial Growth Factor A | 2008 |
Radical scavengers for elderly patients with age-related hearing loss.
Topics: Aged; Aged, 80 and over; Alanine; Ascorbic Acid; Audiometry, Pure-Tone; Drug Therapy, Combination; Ear, Inner; Female; Free Radical Scavengers; Humans; Male; Pilot Projects; Presbycusis; Quinolones; Sensory Thresholds; Thioctic Acid | 2009 |
Rebamipide enema therapy for left-sided ischemic colitis patients accompanied by ulcers: open label study.
Topics: Administration, Rectal; Adult; Aged; Aged, 80 and over; Alanine; Colitis, Ischemic; Colitis, Ulcerative; Colon; Colonoscopy; Enema; Fasting; Female; Gastrointestinal Agents; Humans; Length of Stay; Leukocyte Count; Male; Middle Aged; Quinolones; Retrospective Studies; Time Factors; Treatment Outcome; Wound Healing | 2008 |
[Permeabilities of rebamipide via different intestinal mucosa in the diffusion chamber in vitro].
Topics: Alanine; Animals; Antioxidants; Biological Transport; Cell Membrane Permeability; Colon; Female; Humans; Ileum; Intestinal Absorption; Intestinal Mucosa; Intestines; Jejunum; Male; Permeability; Quinolones; Rats; Rats, Wistar | 2008 |
Permeabilities of rebamipide via rat intestinal membranes and its colon specific delivery using chitosan capsule as a carrier.
Topics: Administration, Oral; Alanine; Animals; Anti-Ulcer Agents; Capsules; Chemistry, Pharmaceutical; Chitosan; Colon; Diffusion; Drug Carriers; Gelatin; Glycerides; Ileum; Intestinal Absorption; Intestinal Mucosa; Jejunum; Lauric Acids; Male; Organic Chemicals; Permeability; Quinolones; Rats; Rats, Wistar; Solubility | 2008 |
Rebamipide as an important adjunctive tool in the management of rheumatologic disorders: comment on the article by Kohashi et al.
Topics: Alanine; Animals; Humans; Quinolones; Rheumatic Diseases | 2008 |
Oxidative stress induces gastric epithelial permeability through claudin-3.
Topics: Alanine; Antioxidants; Cell Line, Tumor; Claudin-3; Claudin-4; Gastric Mucosa; Humans; Hydrogen Peroxide; Membrane Proteins; Oxidative Stress; Permeability; Quinolones; RNA, Small Interfering; Tight Junctions | 2008 |
Peptide derivation of poorly absorbable drug allows intestinal absorption via peptide transporter.
Topics: Alanine; Animals; Biological Availability; Caco-2 Cells; Chromatography, High Pressure Liquid; Dipeptides; Enzyme Inhibitors; Glutamine; HeLa Cells; Humans; In Vitro Techniques; Indicators and Reagents; Intestinal Absorption; Intestinal Mucosa; Intestines; Oocytes; Patch-Clamp Techniques; Peptide Transporter 1; Peptides; Quinolones; Rats; Regional Blood Flow; Sodium Dodecyl Sulfate; Symporters; Taurine; Xenopus | 2009 |
Significance of ERK nitration in portal hypertensive gastropathy and its therapeutic implications.
Topics: Alanine; Animals; Enzyme Inhibitors; Ethanol; Extracellular Signal-Regulated MAP Kinases; Gastric Mucosa; Liver Cirrhosis; MAP Kinase Kinase Kinases; Nitrates; Oxidative Stress; Peroxynitrous Acid; Quinolones; Rats; Rats, Sprague-Dawley; Signal Transduction; Stomach Diseases; Tyrosine | 2008 |
Rebamipide affects the efficiency of colchicine for the herpes simplex virus-induced inflammation in a Behcet's disease mouse model.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behcet Syndrome; Colchicine; Enzyme-Linked Immunosorbent Assay; Herpes Simplex; Inflammation; Male; Mice; Mice, Inbred ICR; NADPH Oxidases; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tubulin Modulators | 2008 |
Sjogren's syndrome: promising, new treatment options besides nizatidine.
Topics: Alanine; Antioxidants; Flax; Histamine H2 Antagonists; Humans; Nizatidine; Plant Preparations; Quinolones; Seeds; Sjogren's Syndrome; Treatment Outcome | 2009 |
Novel oral absorption system containing polyamines and bile salts enhances drug transport via both transcellular and paracellular pathways across Caco-2 cell monolayers.
Topics: Absorption; Adjuvants, Pharmaceutic; Administration, Oral; Alanine; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Drug Synergism; Electric Impedance; Epithelium; Humans; Mouth Mucosa; Patch-Clamp Techniques; Quinolones; Spermine; Taurocholic Acid | 2009 |
Rebamipide, a cytoprotective drug, increases gastric mucus secretion in human: evaluations with endoscopic gastrin test.
Topics: Adult; Alanine; Anti-Ulcer Agents; Chromatography, Ion Exchange; Endoscopy, Gastrointestinal; Female; Gastric Juice; Gastric Mucosa; Gastrins; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Mucins; Quinolones | 2009 |
Effect of rebamipide on quality of peptic ulcer healing in rat.
Topics: Alanine; Animals; Anti-Ulcer Agents; Dinoprostone; Drug Therapy, Combination; Gastric Mucosa; Interleukin-8; Male; Omeprazole; Peptic Ulcer; Proton Pump Inhibitors; Quinolones; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stomach; Ultrasonography | 2009 |
Synthesis of some new spiropyranoquinolines and evaluation of their free radical scavenging activity.
Topics: Alanine; Biphenyl Compounds; Cinnamates; Free Radical Scavengers; Free Radicals; Inhibitory Concentration 50; Molecular Structure; Picrates; Pyrans; Quinolines; Quinolones; Spiro Compounds | 2009 |
Rebamipide-promoted restoration of gastric mucosal sonic hedgehog expression after early Helicobacter pylori eradication.
Topics: Alanine; Animals; Anti-Ulcer Agents; Gastric Mucosa; Gerbillinae; Hedgehog Proteins; Helicobacter Infections; Helicobacter pylori; Humans; Quinolones | 2009 |
[Rebamipide inhibited expression of TLR4 and TNF-alpha release in pulmonary epithelial cell line A549 induced by lipopolysaccharide].
Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Epithelial Cells; Humans; Lipopolysaccharides; Lung; Quinolones; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2009 |
Antral ulcers induced by alendronate, a nitrogen-containing biphophonate, in rat stomachs - prophylactic effect of rebamipide.
Topics: Alanine; Alendronate; Animals; Anti-Ulcer Agents; Antioxidants; Bone Density Conservation Agents; Dose-Response Relationship, Drug; Gastric Mucosa; Glutathione; Lipid Peroxidation; Male; Nitrogen; Pyloric Antrum; Quinolones; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Superoxide Dismutase | 2009 |
Protective effect of rebamipide against celecoxib-induced gastric mucosal cell apoptosis.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Apoptosis; Calcium Channels; Celecoxib; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Gastric Mucosa; Humans; Mice; Mice, Inbred C57BL; Protective Agents; Pyrazoles; Quinolones; Sulfonamides | 2010 |
Rebamipide: a gastrointestinal protective drug with pleiotropic activities.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Alendronate; Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Drug Interactions; Gastritis; Helicobacter Infections; Humans; Male; Mice; Quinolones; Randomized Controlled Trials as Topic; Rats; Stomach Ulcer | 2010 |
Protective effect of rebamipide against Helicobacter pylori-CagA-induced effects on gastric epithelial cells.
Topics: Alanine; Animals; Anti-Ulcer Agents; Antigens, Bacterial; Antioxidants; Bacterial Proteins; Cell Line; Dogs; Epithelial Cells; Humans; Interleukin-8; Membrane Proteins; NF-kappa B; Phosphoproteins; Quinolones; Stomach; Time Factors; Zonula Occludens-1 Protein | 2011 |
Rebamipide inhibits tumor necrosis factor-α-induced interleukin-8 expression by suppressing the NF-κB signal pathway in human umbilical vein endothelial cells.
Topics: Active Transport, Cell Nucleus; Alanine; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Humans; I-kappa B Proteins; Interleukin-8; NF-KappaB Inhibitor alpha; Phosphorylation; Quinolones; Signal Transduction; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Umbilical Veins | 2010 |
Rebamipide-induced downregulation of phospholipase D inhibits inflammation and proliferation in gastric cancer cells.
Topics: Alanine; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Isoenzymes; NF-kappa B; Phospholipase D; Promoter Regions, Genetic; Quinolones; Stomach Neoplasms; Transcription, Genetic | 2010 |
Rebamipide promotes healing of colonic ulceration through enhanced epithelial restitution.
Topics: Alanine; Animals; Anti-Ulcer Agents; Cell Line; Colon; Epithelial Cells; Intestinal Mucosa; Male; Quinolones; Rats; Rats, Wistar; Ulcer; Wound Healing | 2011 |
[Investigation of how to prevent mucositis induced by chemoradiotherapy].
Topics: Alanine; Antineoplastic Agents; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Length of Stay; Male; Middle Aged; Mouthwashes; Mucositis; Quinolones | 2011 |
Formulation of solid dispersion of rebamipide evaluated in a rat model for improved bioavailability and efficacy.
Topics: Alanine; Algorithms; Animals; Anti-Ulcer Agents; Area Under Curve; Biological Availability; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Half-Life; Male; Quinolones; Rats; Rats, Sprague-Dawley; Solubility; Solvents; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared | 2011 |
[The effects of Rebamipide and Polaprezinc mouthwash and uptake on mucositis induced by chemotherapy].
Topics: Aged; Alanine; Antineoplastic Agents; Carnosine; Female; Humans; Male; Middle Aged; Mouthwashes; Mucositis; Neoplasms; Organometallic Compounds; Quality of Life; Quinolones; World Health Organization; Zinc Compounds | 2011 |
Preliminary studies on the effect of rebamipide against the trypsin and egg-albumin induced experimental model of asthma.
Topics: Alanine; Animals; Asthma; Disease Models, Animal; Female; Histamine Release; Male; Mice; Ovalbumin; Quinolones; Treatment Outcome; Trypsin | 2011 |
Injectable drug-eluting elastomeric polymer: a novel submucosal injection material.
Topics: Alanine; Animals; Anti-Ulcer Agents; Drug Carriers; Gastric Mucosa; Hyaluronic Acid; Hydrogels; Injections, Intralesional; Polyethylene Glycols; Pressure; Quinolones; Sodium Chloride; Swine | 2012 |
Rebamipide increases mucin-like substance contents and periodic acid Schiff reagent-positive cells density in normal rabbits.
Topics: Alanine; Alcian Blue; Animals; Conjunctiva; Cornea; Female; Mucins; Periodic Acid; Quinolones; Rabbits; Rosaniline Dyes | 2012 |
Rebamipide increases the mucin-like glycoprotein production in corneal epithelial cells.
Topics: Alanine; Cells, Cultured; Cornea; Epithelial Cells; Epithelium, Corneal; Gene Expression; Glycoconjugates; Glycoproteins; Humans; Membrane Proteins; Mucins; Quinolones; Tears | 2012 |
Rebamipide suppresses diclofenac-induced intestinal permeability via mitochondrial protection in mice.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Diclofenac; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Mice; Mitochondria; Mitochondrial Swelling; NAD; Permeability; Quinolones; Random Allocation | 2012 |
Physicochemical, pharmacokinetic and pharmacodynamic evaluations of novel ternary solid dispersion of rebamipide with poloxamer 407.
Topics: Alanine; Animals; Anti-Ulcer Agents; Chemical Phenomena; Drug Evaluation, Preclinical; Gastric Mucosa; Male; Poloxamer; Quinolones; Rats; Rats, Sprague-Dawley; X-Ray Diffraction | 2013 |
A potent preparation method combining neutralization with microfluidization for rebamipide nanosuspensions and its in vivo evaluation.
Topics: Alanine; Animals; Anti-Ulcer Agents; Gastrointestinal Tract; Male; Mice; Microfluidic Analytical Techniques; Nanoparticles; Particle Size; Quinolones; Rats; Rats, Wistar; Solubility; Suspensions; X-Ray Diffraction | 2013 |
Rebamipide attenuates nonsteroidal anti-inflammatory drugs (NSAID) induced lipid peroxidation by the manganese superoxide dismutase (MnSOD) overexpression in gastrointestinal epithelial cells.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Cell Line; Epithelial Cells; Intestine, Small; Lipid Peroxidation; Membrane Potential, Mitochondrial; Mitochondria; Quinolones; Rats; Stomach; Superoxide Dismutase | 2012 |
Rebamipide induces dendritic cell recruitment to N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-exposed rat gastric mucosa based on IL-1β upregulation.
Topics: Alanine; Animals; Anti-Ulcer Agents; Cell Line, Tumor; Cell Movement; Dendritic Cells; Gastric Mucosa; Gene Expression; Helicobacter pylori; Humans; Interleukin-1beta; Male; Methylnitronitrosoguanidine; Promoter Regions, Genetic; Quinolones; Rats; Up-Regulation | 2012 |
Anti-gastritis and wound healing effects of Momordicae Semen extract and its active component.
Topics: Alanine; Animals; Anti-Ulcer Agents; Calcitonin Gene-Related Peptide; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Male; Mice; Momordica; Plant Extracts; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Somatostatin; Saponins; Seeds; Skin; Wound Healing | 2013 |
Rebamipide attenuates pain severity and cartilage degeneration in a rat model of osteoarthritis by downregulating oxidative damage and catabolic activity in chondrocytes.
Topics: Alanine; Analgesics; Animals; Arthritis, Experimental; Biomarkers; Cartilage, Articular; Cells, Cultured; Chondrocytes; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression; Humans; Male; Matrix Metalloproteinases, Secreted; Mice; Osteoarthritis; Oxidative Stress; Pain; Pain Measurement; Quinolones; Rats; Rats, Wistar; Severity of Illness Index; Stifle | 2012 |
Rebamipide abolishes Helicobacter pylori CagA-induced phospholipase D1 expression via inhibition of NFκB and suppresses invasion of gastric cancer cells.
Topics: Alanine; Anti-Ulcer Agents; Antigens, Bacterial; Bacterial Proteins; Gene Expression Regulation, Enzymologic; Helicobacter pylori; Humans; Neoplasm Invasiveness; NF-kappa B; Phospholipase D; Quinolones; Stomach Neoplasms; Up-Regulation | 2013 |
Terminal-restriction fragment length polymorphism (T-RFLP) analysis for changes in the gut microbiota profiles of indomethacin- and rebamipide-treated mice.
Topics: Alanine; Animals; Cecum; Disease Models, Animal; DNA, Bacterial; Drug Therapy, Combination; Female; Gastrointestinal Tract; Ileum; Indomethacin; Metagenome; Mice; Mice, Inbred C57BL; Polymorphism, Restriction Fragment Length; Quinolones | 2012 |
Rebamipide ameliorates indomethacin-induced small intestinal injury in rats via the inhibition of matrix metalloproteinases activity.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemokines; Down-Regulation; Indomethacin; Injections, Subcutaneous; Intestinal Mucosa; Male; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Metallothionein; Quinolones; Rats; Rats, Wistar; Up-Regulation | 2012 |
Augmented chondroprotective effect of coadministration of celecoxib and rebamipide in the monosodium iodoacetate rat model of osteoarthritis.
Topics: Administration, Oral; Alanine; Animals; Arthritis, Experimental; Behavior, Animal; Cartilage; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Injections, Intra-Articular; Iodoacetic Acid; Male; Osteoarthritis; Pain; Pyrazoles; Quinolones; Rats; Rats, Wistar; Sulfonamides | 2013 |
Rebamipide inhibits indomethacin-induced small intestinal injury: possible involvement of intestinal microbiota modulation by upregulation of α-defensin 5.
Topics: Alanine; alpha-Defensins; Animals; DNA, Bacterial; Gastrointestinal Agents; Indomethacin; Intestine, Small; Metagenome; Mice; Mice, Inbred C57BL; Quinolones; Up-Regulation | 2013 |
Protection of human corneal epithelial cells from TNF-α-induced disruption of barrier function by rebamipide.
Topics: Adherens Junctions; Alanine; Animals; Antioxidants; beta Catenin; Cadherins; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Dry Eye Syndromes; Electric Impedance; Epithelium, Corneal; Fluorescent Antibody Technique, Indirect; Humans; I-kappa B Proteins; Immunoblotting; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Occludin; Ophthalmic Solutions; Phosphorylation; Quinolones; Rats; Rats, Sprague-Dawley; Tight Junctions; Tumor Necrosis Factor-alpha; Wound Healing; Zonula Occludens-1 Protein | 2013 |
Rebamipide increases barrier function and attenuates TNFα-induced barrier disruption and cytokine expression in human corneal epithelial cells.
Topics: Alanine; Antioxidants; Cell Membrane Permeability; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Electric Impedance; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Fluorescent Antibody Technique, Indirect; Humans; I-kappa B Proteins; Immunoblotting; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tight Junctions; Tumor Necrosis Factor-alpha; Zonula Occludens-1 Protein | 2013 |
Rebamipide suppresses PolyI:C-stimulated cytokine production in human conjunctival epithelial cells.
Topics: Alanine; Animals; Antioxidants; Conjunctiva; Conjunctivitis, Allergic; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Humans; Inflammation; Interferon Inducers; Mice; Mice, Inbred BALB C; Poly I-C; Quinolones; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2013 |
Effect of rebamipide ophthalmic suspension on optical quality in the short break-up time type of dry eye.
Topics: Aberrometry; Adult; Aged; Aged, 80 and over; Alanine; Antioxidants; Corneal Topography; Corneal Wavefront Aberration; Dry Eye Syndromes; Female; Humans; Male; Middle Aged; Ophthalmic Solutions; Quinolones; Tears; Visual Acuity | 2013 |
The effect of polaprezinc on gastric mucosal protection in rats with ethanol-induced gastric mucosal damage: comparison study with rebamipide.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Carnosine; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Glutathione Transferase; Heat-Shock Proteins; Heme Oxygenase-1; Male; Organometallic Compounds; Peroxiredoxins; Quinolones; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Superoxide Dismutase; Superoxide Dismutase-1; Vascular Endothelial Growth Factor A; Zinc Compounds | 2013 |
Regulation of human corneal epithelial mucins by rebamipide.
Topics: Alanine; Anti-Ulcer Agents; Biomarkers; Blotting, Western; Cell Line; Cell Proliferation; Epidermal Growth Factor; Epithelium, Corneal; ErbB Receptors; Humans; Ki-67 Antigen; Mucin-1; Mucin-4; Mucin-6; Proliferating Cell Nuclear Antigen; Quinolones; Real-Time Polymerase Chain Reaction | 2014 |
The effects of 2% rebamipide ophthalmic solution on the tear functions and ocular surface of the superoxide dismutase-1 (sod1) knockout mice.
Topics: Alanine; Animals; Conjunctiva; Disease Models, Animal; Dose-Response Relationship, Drug; Dry Eye Syndromes; Enzyme Inhibitors; Male; Mice; Mice, Knockout; Ophthalmic Solutions; Quinolones; Superoxide Dismutase; Superoxide Dismutase-1; Tears | 2013 |
A multicenter, open-label, 52-week study of 2% rebamipide (OPC-12759) ophthalmic suspension in patients with dry eye.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Antioxidants; Cornea; Dry Eye Syndromes; Female; Fluorescein; Humans; Male; Middle Aged; Quinolones; Staining and Labeling; Suspensions; Tears; Time Factors; Treatment Outcome; Visual Acuity; Young Adult | 2014 |
Mucosal protective agents prevent exacerbation of NSAID-induced small intestinal lesions caused by antisecretory drugs in rats.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Diclofenac; Dose-Response Relationship, Drug; Gastric Mucins; Gastrointestinal Agents; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Misoprostol; Mucus; Omeprazole; Protective Agents; Proton Pump Inhibitors; Quinolones; Ranitidine; Rats; Rats, Wistar; Sus scrofa; Triazines | 2014 |
Intravesical application of rebamipide suppresses bladder inflammation in a rat cystitis model.
Topics: Administration, Intravesical; Alanine; Animals; Cystitis; Disease Models, Animal; Female; Quinolones; Rats; Rats, Sprague-Dawley | 2014 |
Pharmacokinetic interactions between rebamipide and selected nonsteroidal anti-inflammatory drugs in rats.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Celecoxib; Diclofenac; Drug Interactions; Male; Protein Binding; Pyrazoles; Quinolones; Rats; Rats, Sprague-Dawley; Sulfonamides | 2014 |
Effects of rebamipide on nephrotoxicity associated with selected NSAIDs in rats.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Celecoxib; Cell Adhesion Molecules; Creatinine; Diclofenac; Dinoprostone; Drug Interactions; Kidney; Kidney Diseases; Male; Nitric Oxide; Potassium; Pyrazoles; Quinolones; Rats; Rats, Sprague-Dawley; Sodium; Sulfonamides | 2013 |
Topical rebamipide treatment for superior limbic keratoconjunctivitis in patients with thyroid eye disease.
Topics: Administration, Topical; Adult; Aged; Alanine; Antioxidants; Female; Fluorescein; Fluorescent Dyes; Graves Ophthalmopathy; Humans; Keratoconjunctivitis; Limbus Corneae; Male; Middle Aged; Ophthalmic Solutions; Osmolar Concentration; Quinolones; Retrospective Studies; Rose Bengal; Tears; Treatment Outcome | 2014 |
Usefulness of a new therapy using rebamipide eyedrops in patients with VKC/AKC refractory to conventional anti-allergic treatments.
Topics: Adolescent; Adult; Alanine; Anti-Allergic Agents; Child; Conjunctivitis, Allergic; Female; Humans; Male; Middle Aged; Ophthalmic Solutions; Quinolones; Treatment Outcome; Young Adult | 2014 |
Short-term effects of instillation of a rebamipide suspension on visual function.
Topics: Adult; Alanine; Dry Eye Syndromes; Female; Humans; Instillation, Drug; Male; Middle Aged; Ophthalmic Solutions; Quinolones; Suspensions; Tears; Vision, Ocular; Visual Acuity | 2014 |
Novel submicronized rebamipide liquid with moderate viscosity: significant effects on oral mucositis in animal models.
Topics: Administration, Oral; Alanine; Animals; Anti-Ulcer Agents; Cautery; Disease Models, Animal; Drug Carriers; Glossitis; Male; Nanoparticles; Oral Ulcer; Quinolones; Rats; Stomatitis; Viscosity; X-Rays | 2014 |
Does rebamipide prevent gastric mucosal injury in patients taking aspirin and clopidogrel?
Topics: Alanine; Anti-Ulcer Agents; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Quinolones; Ticlopidine | 2014 |
Rebamipide attenuates autoimmune arthritis severity in SKG mice via regulation of B cell and antibody production.
Topics: Alanine; Animals; Antibody Formation; Arthritis, Experimental; Arthritis, Rheumatoid; Autoimmune Diseases; B-Lymphocytes; Cell Differentiation; Cell Proliferation; Germinal Center; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Quinolones; Spleen; T-Lymphocytes, Regulatory; Th17 Cells | 2014 |
Rebamipide suppresses collagen-induced arthritis through reciprocal regulation of th17/treg cell differentiation and heme oxygenase 1 induction.
Topics: Alanine; Animals; Antirheumatic Agents; Arthritis, Experimental; Autoantibodies; Cell Differentiation; Cytokines; Heme Oxygenase-1; Male; Mice; Mice, Inbred DBA; Quinolones; T-Lymphocytes, Regulatory; Th17 Cells | 2014 |
Anti-inflammatory effects of rebamipide eyedrop administration on ocular lesions in a murine model of primary Sjögren's syndrome.
Topics: Administration, Ophthalmic; Alanine; Animals; Anti-Inflammatory Agents; Cells, Cultured; Disease Models, Animal; Drug Administration Schedule; Female; Gene Expression Regulation; Humans; Interleukin-10; Keratoconjunctivitis; Lacrimal Apparatus; Lactoferrin; Mice; Mucin 5AC; Quinolones; Sjogren's Syndrome | 2014 |
Development of a rebamipide solid dispersion system with improved dissolution and oral bioavailability.
Topics: Alanine; Animals; Biological Availability; Chemistry, Pharmaceutical; Male; Quinolones; Rats; Rats, Sprague-Dawley; Solubility; X-Ray Diffraction | 2015 |
Silica-installed redox nanoparticles for novel oral nanotherapeutics - improvement in intestinal delivery with anti-inflammatory effects.
Topics: Administration, Oral; Alanine; Animals; Anti-Inflammatory Agents; Colitis; Colon; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Liberation; Male; Mice, Inbred ICR; Nanoparticles; Nitrogen Oxides; Oxidation-Reduction; Quinolones; Silicon Dioxide | 2014 |
Effect of rebamipide ophthalmic suspension on signs and symptoms of keratoconjunctivitis sicca in Sjögren syndrome patients with or without punctal occlusions.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Antibodies, Antinuclear; Antioxidants; Autoantibodies; Eyelids; Female; Fluorophotometry; Humans; Keratoconjunctivitis Sicca; Male; Middle Aged; Mucins; Nasolacrimal Duct; Ophthalmic Solutions; Purinergic P2Y Receptor Agonists; Quinolones; Sjogren's Syndrome; Suspensions; Tears | 2014 |
Intravesical application of rebamipide promotes urothelial healing in a rat cystitis model.
Topics: Administration, Intravesical; Alanine; Animals; Cystitis; Disease Models, Animal; Female; Quinolones; Rats; Rats, Sprague-Dawley; Remission Induction; Urothelium | 2014 |
Effect of topical rebamipide on human conjunctival goblet cells.
Topics: Administration, Topical; Aged; Alanine; Conjunctiva; Goblet Cells; Humans; Male; Quinolones | 2014 |
Inhibition by rebamipide of cytokine-induced or lipopolysaccharide-induced chemokine synthesis in human corneal fibroblasts.
Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Chemokine CCL11; Corneal Keratocytes; Corneal Stroma; Enzyme-Linked Immunosorbent Assay; Humans; I-kappa B Kinase; Interleukin-8; Lipopolysaccharides; Quinolones; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2014 |
Protective effects of garlic extract, PMK-S005, against nonsteroidal anti-inflammatory drugs-induced acute gastric damage in rats.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Garlic; Gene Expression Regulation; Male; Plant Extracts; Quinolones; Rats; Rats, Sprague-Dawley; Stomach; Stomach Ulcer | 2014 |
[Therapeutic effect of rebamipide for oral mucositis associated with FEC therapy for breast cancer].
Topics: Adult; Aged; Alanine; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Middle Aged; Quinolones; Stomatitis | 2014 |
Effect of rebamipide on gastric bleeding and ulcerogenic responses induced by aspirin plus clopidogrel under stimulation of acid secretion in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Aspirin; Clopidogrel; Disease Models, Animal; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Male; Platelet Aggregation Inhibitors; Quinolones; Rats, Sprague-Dawley; Stomach Ulcer; Ticlopidine; Treatment Outcome | 2014 |
Preventive effect of rebamipide on N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats.
Topics: Adenocarcinoma; Alanine; Animals; Antioxidants; Carcinogenesis; Carcinogens; Disease Models, Animal; Immunohistochemistry; Male; Methylnitronitrosoguanidine; Quinolones; Rats; Rats, Sprague-Dawley; Stomach Neoplasms | 2015 |
Rebamipide attenuates 5-Fluorouracil-induced small intestinal mucositis in a mouse model.
Topics: Alanine; Animals; Anti-Ulcer Agents; Antimetabolites, Antineoplastic; Apoptosis; Disease Models, Animal; Fluorouracil; Glutathione; Intestine, Small; Macrophages; Male; Mice, Inbred BALB C; Mucositis; Nitric Oxide Synthase Type II; Quinolones; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2015 |
Gastroprotective efficacy and safety evaluation of scoparone derivatives on experimentally induced gastric lesions in rodents.
Topics: Alanine; Animals; Anti-Ulcer Agents; Artemisia; Coumarins; Ethanol; Hydrochloric Acid; Indomethacin; Male; Phytotherapy; Plant Extracts; Quinolones; Rats, Sprague-Dawley; Stomach Ulcer | 2015 |
Long-term rebamipide and diquafosol in two cases of immune-mediated dry eye.
Topics: Administration, Topical; Aged; Alanine; Drug Therapy, Combination; Dry Eye Syndromes; Enzyme Inhibitors; Female; Fluorescein; Fluorescent Dyes; Follow-Up Studies; Graft vs Host Disease; Humans; Middle Aged; Ophthalmic Solutions; Pemphigoid, Benign Mucous Membrane; Polyphosphates; Purinergic P2Y Receptor Agonists; Quinolones; Treatment Outcome; Uracil Nucleotides; Visual Acuity | 2015 |
Rebamipide suppresses TNF-α mediated inflammation in vitro and attenuates the severity of dermatitis in mice.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Transformed; Dermatitis, Allergic Contact; Disease Models, Animal; Gene Expression Regulation; Genes, Reporter; Inflammation Mediators; Lymph Nodes; Macrophage Activation; Macrophages; Male; Mice, Inbred C57BL; NF-kappa B; Oxazolone; Quinolones; Severity of Illness Index; Signal Transduction; Skin; Tumor Necrosis Factor-alpha | 2015 |
Rebamipide Alters the Esophageal Microbiome and Reduces the Incidence of Barrett's Esophagus in a Rat Model.
Topics: Alanine; Animals; Anti-Ulcer Agents; Barrett Esophagus; Clostridium; Disease Models, Animal; Enterococcus; Esophagus; Lactobacillus; Male; Microbiota; Polymorphism, Restriction Fragment Length; Quinolones; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Streptococcus | 2015 |
Rebamipide delivered by brushite cement enhances osteoblast and macrophage proliferation.
Topics: Alanine; Animals; Bone Cements; Calcium Phosphates; Cell Differentiation; Cell Line; Cell Proliferation; Delayed-Action Preparations; Macrophages; Mice; Osteoblasts; Quinolones | 2015 |
Effectiveness and relevant factors of 2% rebamipide ophthalmic suspension treatment in dry eye.
Topics: Aged; Alanine; Antioxidants; Cornea; Dry Eye Syndromes; Enzyme Inhibitors; Female; Fluorescein; Fluorescent Dyes; Humans; Male; Ophthalmic Solutions; Quinolones; Retrospective Studies; Suspensions | 2015 |
Rebamipide Promotes the Regeneration of Aspirin-Induced Small-Intestine Mucosal Injury through Accumulation of β-Catenin.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; beta Catenin; Body Weight; Cell Division; Cyclooxygenase 2; Dinoprostone; Female; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Permeability; Proto-Oncogene Proteins c-myc; Quinolones; Random Allocation; Regeneration; RNA, Messenger; Tight Junctions | 2015 |
Risk factors for small bowel bleeding in chronic nonsteroidal anti-inflammatory drug users.
Topics: Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Capsule Endoscopy; Coronary Artery Disease; Female; Gastrointestinal Hemorrhage; Humans; Incidence; Intestine, Small; Male; Middle Aged; Platelet Aggregation Inhibitors; Pyridines; Quinolones; Retrospective Studies; Risk Factors | 2015 |
[Efficacy of Rebamipide Gargle against Chemotherapy-induced Oral Mucositis].
Topics: Adult; Aged; Aged, 80 and over; Alanine; Antineoplastic Agents; Antioxidants; Dinoprostone; Epoprostenol; Female; Gastric Mucosa; Humans; Male; Middle Aged; Mouthwashes; Quality of Life; Quinolones; Solutions; Stomatitis; Treatment Outcome | 2015 |
Rebamipide does not interfere with the antitumor effect of radiotherapy or chemotherapy in human oral tumor-bearing nude mice.
Topics: Alanine; Animals; Antineoplastic Agents; Antioxidants; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Disease Models, Animal; Docetaxel; Drug Interactions; Female; Humans; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Quinolones; Radiotherapy; Stomatitis; Taxoids | 2015 |
[A Case of Corneal Injury due to Herbicide Containing Paraquat: Effectiveness of 2% Rebamipide Eye Drops].
Topics: Aged, 80 and over; Alanine; Corneal Diseases; Female; Herbicides; Humans; Ophthalmic Solutions; Oxidative Stress; Paraquat; Quinolones | 2015 |
Celecoxib or diclofenac hepatic status in the presence or absence of rebamipide.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Male; Quinolones; Rats; Rats, Sprague-Dawley | 2015 |
Rebamipide Suppresses Monosodium Urate Crystal-Induced Interleukin-1β Production Through Regulation of Oxidative Stress and Caspase-1 in THP-1 Cells.
Topics: Alanine; Ascorbic Acid; Caspase 1; Cell Line; Colchicine; Dexamethasone; Enzyme Activation; Gout; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1beta; NAD; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Quinolones; Reactive Oxygen Species; Signal Transduction; Uric Acid; Vascular Cell Adhesion Molecule-1 | 2016 |
Rebamipide suppresses mite-induced asthmatic responses in NC/Nga mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Alanine; Allergens; Animals; Antigens, Dermatophagoides; Antioxidants; Asthma; Bronchoalveolar Lavage Fluid; Chemokine CCL11; Chemokine CCL24; Cytokines; Deoxyguanosine; Disease Models, Animal; Interleukin-33; Lung; Macrophages; Male; Mice; Quinolones; Respiratory Hypersensitivity; RNA, Messenger | 2015 |
Effect of rebamipide ophthalmic suspension on the success of lacrimal stent intubation.
Topics: Aged; Aged, 80 and over; Alanine; Anti-Ulcer Agents; Female; Humans; Intubation; Lacrimal Duct Obstruction; Male; Middle Aged; Nasolacrimal Duct; Ophthalmic Solutions; Postoperative Care; Prognosis; Quinolones; Stents; Suspensions | 2016 |
Rebamipide as a novel addition to the antivitiligo ordnance.
Topics: Alanine; Antioxidants; Cytokines; Humans; Oxidative Stress; Quinolones; Vitiligo | 2015 |
[Basic Studies on the Stability of Flavored Oral Solutions of Rebamipide].
Topics: Administration, Oral; Alanine; Anti-Ulcer Agents; Drug Stability; Humans; Quinolones; Stomatitis | 2015 |
Rebamipide retards CCl4-induced hepatic fibrosis in rats: Possible role for PGE2.
Topics: Alanine; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Carbon Tetrachloride; Collagen; Dinoprostone; Disease Models, Animal; Fibrosis; Humans; Interleukin-10; Liver; Liver Cirrhosis; Male; Oxidative Stress; Quinolones; Rats, Wistar; Up-Regulation | 2016 |
The solid state of rebamipide: preparation, characterization, and dissolution.
Topics: Alanine; Anti-Ulcer Agents; Crystallization; Drug Compounding; Drug Stability; Drug Storage; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Quinolones; Solubility; Spectroscopy, Fourier Transform Infrared; Temperature; X-Ray Diffraction | 2016 |
Evaluation of Tear Meniscus Dynamics Using Anterior Segment Swept-Source Optical Coherence Tomography After Topical Solution Instillation for Dry Eye.
Topics: Administration, Topical; Adult; Alanine; Anterior Eye Segment; Cross-Sectional Studies; Dry Eye Syndromes; Female; Humans; Hyaluronic Acid; Male; Ophthalmic Solutions; Polyphosphates; Prospective Studies; Quinolones; Tears; Tomography, Optical Coherence; Uracil Nucleotides | 2016 |
[Evaluation of Gastric Mucosal Injury Model Animals of Rebamipide Formulation--Study of Therapeutic Equivalence].
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Disease Models, Animal; Drug Compounding; Drugs, Generic; Gastric Mucosa; Indomethacin; Lipid Peroxides; Male; Quinolones; Rats, Wistar; Stomach Ulcer; Therapeutic Equivalency | 2016 |
Rebamipide Attenuates Mandibular Condylar Degeneration in a Murine Model of TMJ-OA by Mediating a Chondroprotective Effect and by Downregulating RANKL-Mediated Osteoclastogenesis.
Topics: Administration, Oral; Alanine; Animals; Anti-Inflammatory Agents; Apoptosis; Arthritis, Experimental; Cartilage, Articular; Chondrocytes; Drug Administration Schedule; Extracellular Matrix; Gene Expression Regulation; Mandibular Condyle; Matrix Metalloproteinase 13; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; NFATC Transcription Factors; Nitric Oxide Synthase Type II; Osteoarthritis; Osteoclasts; Osteogenesis; Quinolones; RANK Ligand; Signal Transduction; Temporomandibular Joint; Temporomandibular Joint Disorders | 2016 |
Rebamipide attenuates Helicobacter pylori CagA-induced self-renewal capacity via modulation of β-catenin signaling axis in gastric cancer-initiating cells.
Topics: Alanine; Animals; Anticarcinogenic Agents; Antigens, Bacterial; Apoptosis; Bacterial Proteins; beta Catenin; Cell Line, Tumor; Cell Self Renewal; Helicobacter Infections; Helicobacter pylori; Humans; In Situ Nick-End Labeling; Mice, SCID; Quinolones; Signal Transduction; Stomach Neoplasms; Xenograft Model Antitumor Assays | 2016 |
Rebamipide prevents peripheral arthritis and intestinal inflammation by reciprocally regulating Th17/Treg cell imbalance in mice with curdlan-induced spondyloarthritis.
Topics: Alanine; Animals; Arthritis, Experimental; beta-Glucans; Cytokines; Inflammation; Inflammation Mediators; Interleukin-17; Intestines; Joints; Mice, Inbred BALB C; Quinolones; Spine; Spondylarthritis; T-Lymphocytes, Regulatory; Th17 Cells; Tumor Necrosis Factor-alpha | 2016 |
Size effect of rebamipide ophthalmic nanodispersions on its therapeutic efficacy for corneal wound healing.
Topics: Alanine; Animals; Antioxidants; Cell Line; Corneal Injuries; Disease Models, Animal; Epithelium, Corneal; Humans; Male; Nanoparticles; Ophthalmic Solutions; Particle Size; Quinolones; Rats; Rats, Long-Evans; Rats, Wistar; Treatment Outcome; Wound Healing | 2016 |
Do Cyclosporine A, an IL-1 Receptor Antagonist, Uridine Triphosphate, Rebamipide, and/or Bimatoprost Regulate Human Meibomian Gland Epithelial Cells?
Topics: Alanine; Antihypertensive Agents; Antioxidants; Antirheumatic Agents; Bimatoprost; Cell Count; Cell Proliferation; Cell Survival; Cells, Cultured; Cyclosporine; Dry Eye Syndromes; Epithelial Cells; Humans; Immunosuppressive Agents; Interleukin 1 Receptor Antagonist Protein; Meibomian Glands; Quinolones; Signal Transduction; Uridine Triphosphate | 2016 |
Effect of proinflammatory cytokine IL-6 on efflux transport of rebamipide in Caco-2 cells.
Topics: Alanine; Anti-Ulcer Agents; Caco-2 Cells; Humans; Interleukin-6; Quinolones | 2017 |
Solid-state amorphization of rebamipide and investigation on solubility and stability of the amorphous form.
Topics: Alanine; Calorimetry, Differential Scanning; Desiccation; Drug Stability; Povidone; Powders; Quinolones; Solubility; Ultrasonic Waves; X-Ray Diffraction | 2017 |
Differential effect of rebamipide on transmembrane mucin biosynthesis in stratified ocular surface epithelial cells.
Topics: Alanine; Antioxidants; Blotting, Western; CA-125 Antigen; Cell Differentiation; Cell Membrane Permeability; Cells, Cultured; Epithelium, Corneal; Gene Expression Regulation; Humans; Membrane Proteins; Quinolones; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2016 |
Complementarity of in vitro and in vivo models for the evaluation of gastro-protective effects of pharmacological substances.
Topics: Alanine; Animals; Anti-Ulcer Agents; Cimetidine; Dose-Response Relationship, Drug; Gastric Mucosa; Indomethacin; L-Lactate Dehydrogenase; Male; Mitochondria; Quinolones; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Sucralfate | 2017 |
Rebamipide induces the gastric mucosal protective factor, cyclooxygenase-2, via activation of 5'-AMP-activated protein kinase.
Topics: Alanine; AMP-Activated Protein Kinases; Animals; Anti-Ulcer Agents; Cyclooxygenase 2; Dinoprostone; Enzyme Activation; Gastric Mucosa; Male; Mice, Inbred ICR; Quinolones; Stomach Ulcer | 2017 |
Rebamipide, an anti-ulcerative drug, inhibits induction of salivary dysfunction by benzodiazepines.
Topics: Alanine; Animals; Anti-Ulcer Agents; Central Nervous System Agents; Diazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Quinolones; Rats; Rats, Wistar; Treatment Outcome; Xerostomia | 2017 |
Taste-Masking Effect of Chlorogenic Acid (CGA) on Bitter Drugs Evaluated by Taste Sensor and Surface Plasmon Resonance on the Basis of CGA-Drug Interactions.
Topics: Alanine; Amlodipine; Chlorogenic Acid; Diclofenac; Diphenhydramine; Donepezil; Drug Interactions; Etodolac; Indans; Piperidines; Quinolones; Surface Plasmon Resonance; Taste | 2017 |
A Clinic-based Survey of Clinical Characteristics and Practice Pattern of Dry Eye in Japan.
Topics: Aged; Alanine; Cross-Sectional Studies; Diagnostic Techniques, Ophthalmological; Dry Eye Syndromes; Female; Humans; Hyaluronic Acid; Japan; Male; Middle Aged; Ophthalmic Solutions; Polyphosphates; Practice Patterns, Physicians'; Prevalence; Quinolones; Symptom Assessment; Treatment Outcome; Uracil Nucleotides | 2017 |
Intra-oral administration of rebamipide liquid prevents tongue injuries induced by X-ray irradiation in rats.
Topics: Administration, Oral; Alanine; Animals; Anti-Ulcer Agents; Humans; Male; Quinolones; Rats; Rats, Sprague-Dawley; Stomatitis; Tongue; X-Rays | 2017 |
Rebamipide ameliorates atherosclerosis by controlling lipid metabolism and inflammation.
Topics: Alanine; Animals; Antioxidants; Aorta; Apolipoproteins E; Arthritis; Atherosclerosis; Collagen; Foam Cells; Forkhead Transcription Factors; Inflammation; Interleukin-17; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Quinolones; T-Lymphocytes, Regulatory; Th17 Cells | 2017 |
The potential curative effect of rebamipide in hepatic ischemia/reperfusion injury.
Topics: Alanine; Animals; Apoptosis; Energy Metabolism; Liver; Male; p38 Mitogen-Activated Protein Kinases; Quinolones; Rats; Rats, Wistar; Reperfusion Injury; Sirtuin 1; Transcription Factor RelA | 2017 |
Preparation of an Ultrafine Rebamipide Ophthalmic Suspension with High Transparency.
Topics: Administration, Ophthalmic; Alanine; Animals; Anti-Ulcer Agents; Conjunctiva; Cornea; Crystallization; Dialysis; Male; Mucins; Ophthalmic Solutions; Particle Size; Quinolones; Rabbits; Suspensions; X-Ray Diffraction | 2017 |
Effects of a Rebamipide Mouthwash on Stomatitis Caused by Cancer Chemotherapy-Evaluation of the Efficacy by Patients Themselves.
Topics: Aged; Aged, 80 and over; Alanine; Antineoplastic Agents; Colorectal Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Mouthwashes; Quinolones; Rectal Neoplasms; Stomatitis; Treatment Outcome | 2017 |
Rebamipide ameliorates radiation-induced intestinal injury in a mouse model.
Topics: Alanine; Animals; Bacterial Translocation; beta Catenin; Cell Proliferation; Cytokines; Cytoprotection; Dose-Response Relationship, Drug; Enteritis; Epithelial Cells; Inflammation Mediators; Intestinal Mucosa; Male; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Quinolones; Radiation Injuries, Experimental; Radiation-Protective Agents; Tight Junctions; Time Factors | 2017 |
Implementation of Quality by Design for Formulation of Rebamipide Gastro-retentive Tablet.
Topics: Alanine; Anti-Ulcer Agents; Delayed-Action Preparations; Drug Compounding; Drug Liberation; Excipients; Gastrointestinal Agents; Quinolones; Tablets | 2017 |
Rebamipide reduces amyloid-β 1-42 (Aβ42) production and ameliorates Aβ43-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells.
Topics: Alanine; Alzheimer Disease; Amyloid beta-Peptides; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Gene Expression; Humans; Neurons; Peptide Fragments; Quinolones; Sirtuin 1 | 2017 |
Rebamipide upregulates mucin secretion of intestinal goblet cells via Akt phosphorylation.
Topics: Alanine; Cell Line; Cell Survival; Gene Expression Regulation; Goblet Cells; Humans; Intestinal Mucosa; Mucins; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinolones; RNA, Messenger | 2017 |
Rebamipide solution: a novel submucosal injection material to promote healing speed and healing quality of ulcers induced by endoscopic submucosal dissection.
Topics: Alanine; Animals; Anti-Ulcer Agents; Endoscopic Mucosal Resection; Female; Fibrosis; Gastric Mucosa; Injections; Quinolones; Single-Blind Method; Stomach Diseases; Stomach Ulcer; Surgical Wound; Swine; Wound Healing | 2018 |
Rebamipide alleviates radiation-induced colitis through improvement of goblet cell differentiation in mice.
Topics: Alanine; Animals; Anti-Ulcer Agents; Cell Differentiation; Cell Proliferation; Colitis; Colon; Disease Models, Animal; Epithelial Cells; Gene Expression; Goblet Cells; HT29 Cells; Humans; Male; Mice, Inbred C57BL; Mucin-2; Quinolones; Radiation Injuries, Experimental; Radiation, Ionizing; Radiotherapy | 2018 |
Rebamipide protects against glaucoma eyedrop-induced ocular surface disorders in rabbits.
Topics: Alanine; Animals; Conjunctiva; Corneal Diseases; Female; Fluorescein; Glaucoma; Microscopy, Electron, Scanning; Ophthalmic Solutions; Quinolones; Rabbits; Rose Bengal | 2017 |
Rebamipide suppresses 5-fluorouracil-induced cell death via the activation of Akt/mTOR pathway and regulates the expression of Bcl-2 family proteins.
Topics: Alanine; Animals; Antimetabolites; Antioxidants; Cell Death; Cell Survival; Fluorouracil; Gene Expression Regulation; Humans; Keratinocytes; Mucositis; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Quinolones; TOR Serine-Threonine Kinases | 2018 |
Additive Effects of Rebamipide Plus Proton Pump Inhibitors on the Expression of Tight Junction Proteins in a Rat Model of Gastro-Esophageal Reflux Disease.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Alanine; Animals; Anti-Ulcer Agents; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Esophageal Mucosa; Gastroesophageal Reflux; Male; Pantoprazole; Proton Pump Inhibitors; Quinolones; Rats; Rats, Sprague-Dawley; Tight Junction Proteins | 2018 |
Efficacy of Rebamipide Instillation for Contact Lens Discomfort With Dry Eye.
Topics: Adult; Alanine; Antioxidants; Contact Lenses, Hydrophilic; Cytokines; Dry Eye Syndromes; Female; Humans; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Quinolones; Tears; Young Adult | 2018 |
Rebamipide suppresses TNF-α production and macrophage infiltration in the conjunctiva.
Topics: Alanine; Animals; Anti-Inflammatory Agents; Conjunctiva; Cornea; Corneal Injuries; Enzyme-Linked Immunosorbent Assay; Female; Macrophages; Mice; Mice, Inbred C57BL; Quinolones; Tumor Necrosis Factor-alpha; Wound Healing | 2018 |
[Development of "Patient Friendly Formulations" to Counter the Side Effects of Cancer Chemotherapy].
Topics: Administration, Oral; Alanine; Animals; Antineoplastic Agents; Cell Communication; Cyclic AMP; Disease Models, Animal; Drug Compounding; Evidence-Based Medicine; Gastric Mucosa; Humans; Mouthwashes; Quinolones; Stomatitis; Treatment Outcome; Triazines | 2018 |
Rebamipide in Functional and Organic Dyspepsia: Sometimes the Best Offense Is a Good Defense.
Topics: Alanine; Dyspepsia; Quinolones | 2018 |
Mucus reduction promotes acetyl salicylic acid-induced small intestinal mucosal injury in rats.
Topics: Alanine; Animals; Aspirin; Intestinal Mucosa; Intestine, Small; Male; Mucus; Polysorbates; Protective Agents; Quinolones; Rats, Sprague-Dawley | 2018 |
The Role of 2% Rebamipide Eye Drops Related to Conjunctival Differentiation in Superoxide Dismutase-1 (Sod1) Knockout Mice.
Topics: Alanine; Animals; Antioxidants; Biomarkers; Cell Differentiation; Conjunctiva; Disease Models, Animal; Dry Eye Syndromes; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Ophthalmic Solutions; Quinolones; RNA, Messenger; Superoxide Dismutase-1; Tears | 2018 |
Capmul MCM/Solutol HS15-Based Microemulsion for Enhanced Oral Bioavailability of Rebamipide.
Topics: Alanine; Animals; Biological Availability; Diglycerides; Drug Carriers; Emulsions; Jejunum; Male; Monoglycerides; Nanospheres; Particle Size; Polyethylene Glycols; Quinolones; Rats; Rats, Sprague-Dawley; Stearic Acids | 2017 |
[The Efficacy of Rebamipide or Ecabet Sodium Supplementation for Helicobacter pylori Eradication Therapy Compared with Quadruple (Concomitant) Regimen].
Topics: Abietanes; Adult; Aged; Alanine; Anti-Bacterial Agents; Anti-Ulcer Agents; Breath Tests; Drug Administration Schedule; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Patient Compliance; Proton Pump Inhibitors; Quinolones; Retrospective Studies; Treatment Outcome | 2018 |
Therapeutic efficacy of rebamipide-loaded PLGA nanoparticles coated with chitosan in a mouse model for oral mucositis induced by cancer chemotherapy.
Topics: Alanine; Animals; Anti-Ulcer Agents; Chitosan; Coated Materials, Biocompatible; Drug Liberation; Fluorouracil; Lactic Acid; Male; Mice, Inbred ICR; Microscopy, Electron, Scanning; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quinolones; Stomatitis; Treatment Outcome | 2018 |
Using human iPS cell-derived enterocytes as novel in vitro model for the evaluation of human intestinal mucosal damage.
Topics: Alanine; Animal Testing Alternatives; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cell Membrane Permeability; Cells, Cultured; Enterocytes; Humans; Indomethacin; Induced Pluripotent Stem Cells; Microfilament Proteins; Mucin-2; Quinolones | 2018 |
Comparison of Ocular Surface Mucin Expression After Topical Ophthalmic Drug Administration in Dry Eye-Induced Mouse Model.
Topics: Administration, Topical; Alanine; Animals; Anti-Inflammatory Agents; Cyclosporine; Disease Models, Animal; Dry Eye Syndromes; Epithelium, Corneal; Female; Inflammation; Mice; Mice, Inbred C57BL; Mucins; Ophthalmic Solutions; Polyphosphates; Quinolones; Uracil Nucleotides | 2018 |
The Effect of Rebamipide Ophthalmic Solution on Cytokine and Mucin Secretion in Culture of Conjunctival Epithelial Cells From the Cu, Zn-Superoxide Dismutase-1 (SOD-1) Knock-Down Mouse.
Topics: Alanine; Animals; Antioxidants; Cells, Cultured; Conjunctiva; Conjunctival Diseases; Copper; Cytokines; Disease Models, Animal; Epithelial Cells; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucins; Ophthalmic Solutions; Quinolones; Superoxide Dismutase-1; Zinc | 2019 |
Chemopreventive Effect of Rebamipide against Gastric Cancer in Patients who undergo Endoscopic Resection for Early Gastric Neoplasms: A Nationwide Claims Study.
Topics: Administrative Claims, Healthcare; Aged; Alanine; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Endoscopic Mucosal Resection; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Quinolones; Republic of Korea; Retrospective Studies; Stomach Neoplasms | 2019 |
Polyvinyl alcohol-iodine induced corneal epithelial injury in vivo and its protection by topical rebamipide treatment.
Topics: Administration, Ophthalmic; Alanine; Animals; Antioxidants; Corneal Injuries; Epithelium, Corneal; Iodine; Male; Polyvinyl Alcohol; Protective Agents; Quinolones; Rabbits | 2018 |
Lipid Nanoemulsions of Rebamipide: Formulation, Characterization, and In Vivo Evaluation of Pharmacokinetic and Pharmacodynamic Effects.
Topics: Administration, Oral; Alanine; Animals; Anti-Ulcer Agents; Drug Evaluation, Preclinical; Emulsifying Agents; Gastric Mucosa; Lipids; Male; Nanoparticles; Particle Size; Quinolones; Rats; Rats, Wistar | 2019 |
Rebamipide Mitigates Impairments in Mitochondrial Function and Bioenergetics with α-Synuclein Pathology in 6-OHDA-Induced Hemiparkinson's Model in Rats.
Topics: Administration, Oral; Alanine; alpha-Synuclein; Animals; Antioxidants; Antiparkinson Agents; Apoptosis; Dose-Response Relationship, Drug; Energy Metabolism; Functional Laterality; Male; Mitochondria; Motor Activity; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Quinolones; Random Allocation; Rats; Substantia Nigra | 2019 |
Preparation of Cocoa Powder-Containing Orally Disintegrating Tablets of Rebamipide (Rebamipide Chocolet) and Evaluation of Their Clinical Palatability.
Topics: Administration, Oral; Adult; Alanine; Antioxidants; Chocolate; Drug Compounding; Excipients; Humans; Mechanical Phenomena; Quinolones; Solubility; Sweetening Agents; Tablets | 2019 |
Response.
Topics: Alanine; Endoscopic Mucosal Resection; Humans; Quinolones; Ulcer | 2019 |
Submucosal injection materials other than mucosal lift.
Topics: Alanine; Endoscopic Mucosal Resection; Humans; Mucous Membrane; Quinolones; Ulcer | 2019 |
Rebamipide ophthalmic solution modulates the ratio of T helper cell 17/regulatory T cells in dry eye disease mice.
Topics: Alanine; Animals; Conjunctiva; Cornea; Cytokines; Disease Models, Animal; Dry Eye Syndromes; Female; Lacrimal Apparatus; Mice; Mice, Inbred C57BL; Ophthalmic Solutions; Quinolones; T-Lymphocytes, Regulatory; Th17 Cells | 2019 |
Rebamipide solution as a submucosal injection material for possible prevention of gastric stenosis after endoscopic submucosal dissection.
Topics: Alanine; Animals; Anti-Ulcer Agents; Disease Models, Animal; Endoscopic Mucosal Resection; Gastric Mucosa; Injections; Pyloric Stenosis; Quinolones; Swine | 2019 |
Rebamipide increases the disaccharidases activity in patients with enteropathy with impaired membrane digestion. Pilot study.
Topics: Adolescent; Adult; Alanine; Case-Control Studies; Constipation; Diarrhea; Disaccharidases; Female; Humans; Intestinal Mucosa; Irritable Bowel Syndrome; Malabsorption Syndromes; Male; Middle Aged; Pilot Projects; Quinolones; Sucrase; Young Adult | 2019 |
Effectiveness of acid suppressants and other mucoprotective agents in reducing the risk of occult gastrointestinal bleeding in nonsteroidal anti-inflammatory drug users.
Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cohort Studies; Female; Flavonoids; Gastrointestinal Agents; Gastrointestinal Hemorrhage; Hemoglobins; Histamine H2 Antagonists; Humans; Male; Middle Aged; Misoprostol; Osteoarthritis; Proton Pump Inhibitors; Quinolones; Treatment Outcome | 2019 |
Immune modulation by rebamipide in a mouse model of Sjogren's syndrome via T and B cell regulation.
Topics: Alanine; Animals; B-Lymphocytes, Regulatory; Cytokines; Disease Models, Animal; Immunomodulation; Mice; Oxygenases; Quinolones; Salivary Glands; Sjogren's Syndrome; Th17 Cells | 2019 |
The Effects of Rebamipide 2% Ophthalmic Solution Application on Murine Subbasal Corneal Nerves After Environmental Dry Eye Stress.
Topics: Alanine; Animals; Anti-Inflammatory Agents; Cornea; Dry Eye Syndromes; Male; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Peripheral Nerves; Quinolones | 2019 |
Reactions of Rebamipide with Hypobromous Acid.
Topics: Alanine; Bromates; Humans; Hypochlorous Acid; Molecular Structure; Quinolones | 2019 |
Solid Nanocrystals of Rebamipide Promote Recovery from Indomethacin-Induced Gastrointestinal Bleeding.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Gastrointestinal Hemorrhage; Indomethacin; Intestinal Mucosa; Male; Nanoparticles; Nitric Oxide; Quinolones; Rats; X-Ray Diffraction | 2019 |
Graft Versus Host Disease-Associated Dry Eye: Role of Ocular Surface Mucins and the Effect of Rebamipide, a Mucin Secretagogue.
Topics: Administration, Ophthalmic; Alanine; Animals; Antioxidants; Bone Marrow Transplantation; CA-125 Antigen; Disease Models, Animal; Dry Eye Syndromes; Enzyme-Linked Immunosorbent Assay; Eye Proteins; Female; Goblet Cells; Graft vs Host Disease; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Mucin 5AC; Mucin-1; Mucin-4; Mucins; Periodic Acid-Schiff Reaction; Quinolones; Real-Time Polymerase Chain Reaction; Tears; Transplantation, Homologous | 2019 |
Rebamipide-containing Film Using Chitosan and HPMC for Oral Mucositis Induced by Cancer Chemotherapy.
Topics: Alanine; Antineoplastic Agents; Chitosan; Delayed-Action Preparations; Humans; Hypromellose Derivatives; Quinolones; Stomatitis | 2019 |
Rebamipide-loaded chitosan nanoparticles accelerate prostatic wound healing by inhibiting M1 macrophage-mediated inflammation via the NF-κB signaling pathway.
Topics: Alanine; Animals; Cell Proliferation; Chitosan; Dogs; Drug Compounding; Humans; Macrophages; Male; Nanoparticles; NF-kappa B; Prostate; Prostatic Hyperplasia; Quinolones; Wound Healing | 2020 |
Rebamipide promotes lacrimal duct epithelial cell survival via protecting barrier function.
Topics: Alanine; Animals; Anti-Ulcer Agents; Cell Survival; Cells, Cultured; Disease Models, Animal; Electric Impedance; Epithelial Cells; Interleukin-6; Lacrimal Apparatus; Lacrimal Duct Obstruction; Male; Microscopy, Electron, Scanning; Protective Agents; Quinolones; Rabbits | 2020 |
Solubilization of poorly water-soluble bioactive molecules in neutral aqueous media by complexation with renatured β-1,3-1,6-glucan nanoparticles.
Topics: Alanine; Curcumin; gamma-Cyclodextrins; Glucans; Glucosides; Nanoparticles; Quinolones; Solubility; Tretinoin; Water | 2020 |
Pharmaceutical evaluation of matrix tablets prepared using a fused deposition modelling type three-dimensional printer - Effect of geometrical internal microstructural factors on drug release from enteric-polymer tablets containing rebamipide.
Topics: Alanine; Computer-Aided Design; Drug Compounding; Drug Liberation; Polymers; Printing, Three-Dimensional; Quinolones; Solubility; Tablets | 2020 |
Effects of rebamipide for chronic atrophic gastritis: A protocol for systematic review and meta-analysis.
Topics: Alanine; Anti-Ulcer Agents; Gastritis, Atrophic; Humans; Meta-Analysis as Topic; Quinolones; Systematic Reviews as Topic | 2020 |
[Rebamipide using in gastroesophageal reflux disease treatment].
Topics: Alanine; Anti-Ulcer Agents; Gastroesophageal Reflux; Humans; Proton Pump Inhibitors; Quinolones; Vascular Endothelial Growth Factor A | 2020 |
Biopharmaceutical characterization of rebamipide: The role of mucus binding in regional-dependent intestinal permeability.
Topics: Administration, Oral; Alanine; Biological Products; Intestinal Absorption; Intestines; Mucus; Permeability; Quinolones; Solubility | 2020 |
Influence of proton pump inhibitor or rebamipide use on gut microbiota of rheumatoid arthritis patients.
Topics: Alanine; Arthritis, Rheumatoid; Bacteria; DNA, Bacterial; Enzyme Inhibitors; Female; Gastrointestinal Diseases; Gastrointestinal Microbiome; Humans; Male; Middle Aged; Prognosis; Proton Pump Inhibitors; Quinolones | 2021 |
Hepatoprotective effect of rebamipide against methotrexate-induced hepatic intoxication: role of Nrf2/GSK-3β, NF-κβ-p65/JAK1/STAT3, and PUMA/Bax/Bcl-2 signaling pathways.
Topics: Alanine; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Janus Kinase 1; Liver; Male; Methotrexate; Necrosis; NF-E2-Related Factor 2; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Quinolones; Rats, Wistar; Signal Transduction; STAT3 Transcription Factor; Transcription Factor RelA | 2020 |
Protective effect and mechanism of rebamipide on NSAIDs associated small bowel injury.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Claudin-1; Cytokines; Diclofenac; Disease Models, Animal; Gene Expression Regulation; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; NF-kappa B; Quinolones; Rats, Sprague-Dawley; Signal Transduction; Toll-Like Receptor 4; Ulcer; Zonula Occludens-1 Protein | 2021 |
Improvement of lipid solubility and oral bioavailability of a poorly water- and poorly lipid-soluble drug, rebamipide, by utilizing its counter ion and SNEDDS preparation.
Topics: Administration, Oral; Alanine; Biological Availability; Drug Delivery Systems; Emulsions; Lipids; Nanoparticles; Particle Size; Quinolones; Solubility; Water | 2021 |
Rebamipide ameliorates indomethacin-induced small intestinal damage and proton pump inhibitor-induced exacerbation of this damage by modulation of small intestinal microbiota.
Topics: Alanine; Animals; Anti-Ulcer Agents; Gastrointestinal Microbiome; Indomethacin; Intestinal Mucosa; Intestine, Small; Male; Mice; Proton Pump Inhibitors; Quinolones | 2021 |
[Rebamipide: evidence base for use in gastroenterology].
Topics: Alanine; Gastroenterology; Helicobacter Infections; Helicobacter pylori; Humans; Quinolones | 2020 |
Efficacy of 2% Rebamipide Suspension for Vernal Keratoconjunctivitis: A Clinical Comparison with Topical Immune Modulators Cyclosporine and Tacrolimus.
Topics: Administration, Topical; Alanine; Conjunctivitis, Allergic; Cyclosporine; Humans; Immunologic Factors; Immunosuppressive Agents; Ointments; Ophthalmic Solutions; Prospective Studies; Quinolones; Tacrolimus; Treatment Outcome | 2022 |
Development of rebamipide-loaded spray-dried microsphere using distilled water and meglumine: physicochemical characterization and pharmacokinetics in rats.
Topics: Alanine; Animals; Chemical Phenomena; Male; Meglumine; Microspheres; Quinolones; Rats; Rats, Sprague-Dawley; Solubility; Water; X-Ray Diffraction | 2021 |
Development and Validation of Four Spectrophotometric Methods for Assay of Rebamipide and its Impurity: Application to Tablet Dosage Form.
Topics: Alanine; Quinolones; Spectrophotometry; Tablets | 2022 |
Strengthened rebamipide ocular nanoformulation to effectively treat corneal alkali burns in mice through the HMGB1 signaling pathway.
Topics: Alanine; Animals; Antioxidants; Blotting, Western; Burns, Chemical; Chickens; Chorioallantoic Membrane; Disease Models, Animal; Drug Carriers; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Eye Burns; Glycyrrhizic Acid; HMGB1 Protein; Humans; Mice; Ophthalmic Solutions; Quinolones; Rabbits; Signal Transduction; Sodium Hydroxide; Wound Healing | 2021 |
Engineering a Remedy to Modulate and Optimize Biopharmaceutical Properties of Rebamipide by Synthesizing New Cocrystal: In Silico and Experimental Studies.
Topics: Alanine; Animals; Biological Availability; Biological Products; Carrageenan; Chemical Engineering; Chemistry, Pharmaceutical; Crystallization; Disease Models, Animal; Drug Compounding; Edema; Humans; Hydrogen Bonding; Indomethacin; Male; Powder Diffraction; Quinolones; Rats; Spectroscopy, Fourier Transform Infrared; Stomach Ulcer | 2021 |
The risk of pulmonary adverse drug reactions of rebamipide and other drugs for acid-related diseases: An analysis of the national pharmacovigilance database in South Korea.
Topics: Adverse Drug Reaction Reporting Systems; Aged; Alanine; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmacovigilance; Quinolones; Republic of Korea | 2022 |
Preventive effect of rebamipide on NSAID-induced lower gastrointestinal tract injury using FAERS and JADER.
Topics: Adverse Drug Reaction Reporting Systems; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Databases, Factual; Diclofenac; Drug Therapy, Combination; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Japan; Phenylpropionates; Quinolones; United States; United States Food and Drug Administration | 2022 |
Rebamipide attenuates alcohol-induced gastric epithelial cell injury by inhibiting endoplasmic reticulum stress and activating autophagy-related proteins.
Topics: Alanine; Animals; Anti-Ulcer Agents; Autophagy-Related Proteins; Endoplasmic Reticulum Stress; Epithelial Cells; Ethanol; Gastric Mucosa; Gastritis; Mice; Quinolones | 2022 |
Electrostatic molecular effect of differently charged surfactants on the solubilization capacity and physicochemical properties of salt-caged nanosuspensions containing pH-dependent and poorly water-soluble rebamipide.
Topics: Alanine; Cetrimonium; Hydrogen-Ion Concentration; Quinolones; Sodium Chloride; Solubility; Static Electricity; Surface-Active Agents; Water | 2022 |
Design and evaluation of in vivo bioavailability in beagle dogs of bilayer tablet consisting of immediate release nanosuspension and sustained release layers of rebamipide.
Topics: Alanine; Animals; Biological Availability; Delayed-Action Preparations; Dogs; Poloxamer; Quinolones; Solubility; Tablets; Water | 2022 |
Frequently reported adverse events of rebamipide compared to other drugs for peptic ulcer and gastroesophageal reflux disease.
Topics: Adverse Drug Reaction Reporting Systems; Aged; Alanine; Gastroesophageal Reflux; Humans; Peptic Ulcer; Quinolones; Xerostomia | 2022 |