alanine has been researched along with oligonucleotides in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (26.53) | 18.7374 |
| 1990's | 6 (12.24) | 18.2507 |
| 2000's | 24 (48.98) | 29.6817 |
| 2010's | 5 (10.20) | 24.3611 |
| 2020's | 1 (2.04) | 2.80 |
| Authors | Studies |
|---|---|
| Ikehara, M; Nishikawa, S; Ohtsuka, E; Takemura, S | 1 |
| Altman, S; Garber, RL; Siddiqui, MA | 1 |
| Dirheimer, G; Martin, R; Penswick, JR | 1 |
| Ikehara, M | 1 |
| Gao, X; Gazit, E; Livneh, A; Stastny, P | 1 |
| Bailey, JM; Brandts, JF; Lin, LN; Mas, MT | 1 |
| Carrell, RW; Daly, M; Fairham, S; Harper, PL; Perry, DJ | 1 |
| Hakoshima, T; Ikehara, M; Kimura, T; Morioka, H; Nishikawa, S; Ohtsuka, E; Tomita, K; Uesugi, S | 1 |
| Holley, RW; Powers, DM | 1 |
| Fischer, D; Kössel, H; Schott, H | 1 |
| Lessard, JL; Pestka, S | 1 |
| Khorana, HG; Weber, H | 1 |
| Ikehara, M; Morioka, S; Otsuka, E; Ubasawa, M | 1 |
| Profy, AT; Usher, DA | 1 |
| Balland, A; de la Salle, H; Findeli, A; Jaye, M; Kohli, V; Lecocq, JP; Schamber, F; Tolstoshev, P | 1 |
| Gripon, P; Guguen-Guillouzo, C; Le Seyec, J; Rumin, S | 1 |
| Hull, RA; Hull, SI; Klann, AG; Palzkill, T | 1 |
| McFadden, BA; Rehman, A | 1 |
| Arbuthnott, K; Casipit, CL; Chavaillaz, PA; Jiao, JA; Tal, R; Weidanz, JA; Wittman, V; Wong, HC | 1 |
| Haruki, M; Iwai, S; Kanaya, S; Morikawa, M; Tsunaka, Y | 1 |
| Park, C; Raines, RT; Schultz, LW | 1 |
| Lee, JH; Skalnik, DG; Voo, KS | 1 |
| Huye, LE; Jiang, MM; Purugganan, MM; Roth, DB | 1 |
| Harley, MJ; Schildbach, JF; Toptygin, D; Troxler, T | 1 |
| Bergnes, G; Berlin, V; Bureau, P; Kluge, AF; Murthi, KK; Smith, SE | 1 |
| Benedetti, P; Bruselles, A; Chillemi, G; Desideri, A; Falconi, M; Fiorani, P | 1 |
| Crooke, ST; Lima, WF; Nichols, JG; Prakash, TP; Ravikumar, V; Wu, H | 1 |
| Ahuja, U; Thöny-Meyer, L | 1 |
| Dodson, ML; Lloyd, RS; Meador, MG; Rajagopalan, L | 1 |
| Leonard, M; Schmid, SL; Song, BD | 1 |
| Schimmel, P; Tamura, K | 1 |
| De Felice, M; Onesti, S; Pisani, FM; Pucci, B; Rossi, M | 1 |
| D'Arco, M; Fabbretti, E; Fabbro, A; Giniatullin, R; Masten, L; Nistri, A; Sokolova, E | 1 |
| Ammerer, G; Durchschlag, E; Reiter, W; Schüller, C | 1 |
| Doi, Y; Hiraishi, T; Kikkawa, Y; Muneta, K; Narike, M; Normi, YM; Saito, Y; Tsuge, T | 1 |
| Bujnicki, JM; Kondrzycka-Dada, A; Piekarowicz, A; Radlinska, M | 1 |
| André, B; Calderon, IL; Tenreiro, S; Velasco, I | 1 |
| Ogura, M; Shimane, K | 1 |
| Agnelli, P; Colombi, P; Curti, B; Dossena, L; Morandi, P; Mulazzi, S; Negri, A; Tedeschi, G; Vanoni, MA | 1 |
| Cauvi, DM; Robertson, MW; Tian, X; von Loehneysen, K | 1 |
| Benard, O; Li, Z; Margolskee, RF | 1 |
| Lee, LC; Lee, YL; Leu, RJ; Shaw, JF | 1 |
| Bell, CE; Bohl, CE; Dalton, JT; Wisler, JW; Wu, Z; Xing, X | 1 |
| Florentiev, V; Kochetkova, S; Kolganova, N; Timofeev, E; Varizhuk, A | 1 |
| Andersson, T; Elias, P; Muylaert, I; Zhao, Z | 1 |
| Aranda, C; Colon, M; Gonzalez, A; Ongay-Larios, L; Peñalosa-Ruiz, G; Quezada, H | 1 |
| Cheatham, TE; Henriksen, NM; Roe, DR | 1 |
| Hashimoto, Y; Kawai, Y; Miyata, K; Nakagawa, O; Tsuda, H; Urata, H; Wada, S | 1 |
| Jia, X; Kai, G; Li, L; Nile, A; Nile, SH; Qiu, J | 1 |
1 review(s) available for alanine and oligonucleotides
| Article | Year |
|---|---|
COVID-19: Pathogenesis, cytokine storm and therapeutic potential of interferons.
Topics: Adenosine Monophosphate; Alanine; Antibodies, Monoclonal; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Cytokine Release Syndrome; Cytokines; Drug Therapy, Combination; Humans; Inflammation; Interferons; Oligonucleotides; Pandemics; Pneumonia, Viral; SARS-CoV-2; Viral Vaccines | 2020 |
48 other study(ies) available for alanine and oligonucleotides
| Article | Year |
|---|---|
Reconstitution of chemically synthesized ribooligonucleotides with naturally occurring tRNA fragments.
Topics: Alanine; Base Sequence; Candida; Hydrogen-Ion Concentration; Kinetics; Magnesium; Nucleic Acid Conformation; Oligonucleotides; Oligoribonucleotides; Ribonucleases; RNA, Transfer | 1976 |
Identification of precursor molecules to individual tRNA species from Bombyx mori.
Topics: Alanine; Animals; Base Sequence; Bombyx; Electrophoresis, Polyacrylamide Gel; Glycine; Nucleic Acid Precursors; Oligonucleotides; RNA, Transfer | 1978 |
Evidence supporting a revised sequence for yeast alanine tRNA.
Topics: Alanine; Base Sequence; Chromatography, DEAE-Cellulose; Countercurrent Distribution; Electrophoresis, Paper; Nucleic Acid Conformation; Oligonucleotides; Pancreas; Ribonucleases; RNA, Transfer; Saccharomyces cerevisiae | 1975 |
Synthesis of ribo-oligonucleotides having the sequence of transfer ribonucleic acid.
Topics: Alanine; Base Sequence; Methods; Nucleic Acid Conformation; Oligonucleotides; Oligoribonucleotides; Ribonucleases; RNA, Transfer; Saccharomyces cerevisiae; Tyrosine | 1975 |
Rheumatoid arthritis in Israeli Jews: shared sequences in the third hypervariable region of DRB1 alleles are associated with susceptibility.
Topics: Alanine; Alleles; Amino Acid Sequence; Arthritis, Rheumatoid; Genetic Predisposition to Disease; Glycine; Histocompatibility Antigens Class II; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Immunoglobulin Variable Region; Israel; Jews; Molecular Sequence Data; Oligonucleotides; Polymerase Chain Reaction; Risk Factors; Valine | 1991 |
Substitution of a proline for alanine 183 in the hinge region of phosphoglycerate kinase: effects on catalysis, activation by sulfate, and thermal stability.
Topics: Alanine; Calorimetry, Differential Scanning; Catalysis; Enzyme Activation; Hot Temperature; Mutation; Oligonucleotides; Phosphoglycerate Kinase; Proline; Protein Conformation; Protein Denaturation; Structure-Activity Relationship; Sulfates; Yeasts | 1990 |
Antithrombin Cambridge, 384 Ala to Pro: a new variant identified using the polymerase chain reaction.
Topics: Adult; Alanine; Antithrombin III; Base Sequence; Chromatography; DNA; DNA-Directed DNA Polymerase; Exons; Family; Female; Gene Amplification; Humans; Mutation; Oligonucleotides; Proline; Thrombosis | 1989 |
Glu 46 of ribonuclease T1 is an essential residue for the recognition of guanine base.
Topics: Alanine; Chromatography, High Pressure Liquid; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Endoribonucleases; Glutamine; Guanine; Hydrogen Bonding; Hydrogen-Ion Concentration; Mutation; Oligonucleotides; Protein Conformation; Recombinant Fusion Proteins; Ribonuclease T1; Structure-Activity Relationship; Substrate Specificity | 1988 |
Selective chemical methylation of yeast alanine transfer RNA.
Topics: Adenine; Alanine; Alkaline Phosphatase; Base Sequence; Carbon Isotopes; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Coliphages; Countercurrent Distribution; Drug Stability; Kinetics; Methylation; Nucleic Acid Conformation; Nucleosides; Oligonucleotides; Phosphoric Diester Hydrolases; Ribonucleases; RNA, Transfer; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Sulfuric Acids; Transfer RNA Aminoacylation; Tritium | 1972 |
Synthesis of four undecanucleotides complementary to a region of the coat protein cistron of phage fd.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Base Sequence; Coliphages; DNA Nucleotidyltransferases; DNA Repair; DNA, Single-Stranded; DNA, Viral; Genetic Code; Genetics, Microbial; Methionine; Nucleic Acid Hybridization; Oligonucleotides; Phosphoric Diester Hydrolases; Polynucleotides; Snakes; Spectrophotometry, Ultraviolet; Spleen; Tryptophan; Valine; Venoms; Viral Proteins | 1973 |
Studies on the formation of transfer ribonucleic acid-ribosome complexes. XXII. Binding of aminoacyl-oligonucleotides to ribosomes.
Topics: Adenine Nucleotides; Alanine; Amino Acids; Amino Acyl-tRNA Synthetases; Ammonium Chloride; Chromatography, Ion Exchange; Cytosine Nucleotides; Electrophoresis, Paper; Escherichia coli; Ethanol; Glutamates; Leucine; Lysine; Magnesium; Oligonucleotides; Phenylalanine; Polynucleotides; Puromycin; Ribosomes; Serine; Tritium | 1972 |
CIV. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Chemical synthesis of an icosadeoxynucleotide corresponding to the nucleotide sequence 21 to 40.
Topics: Alanine; Base Sequence; Chromatography, DEAE-Cellulose; Genes; Oligonucleotides; Polynucleotides; RNA, Transfer; Saccharomyces cerevisiae | 1972 |
Studies on transfer ribonucleic acids and related compounds. VI. Synthesis of yeast alanine transfer ribonucleic acid 3'-terminal nonanucleotides and 5'-terminal hexanucleotides.
Topics: Alanine; Amino Acid Sequence; Chromatography, DEAE-Cellulose; Indicators and Reagents; Oligonucleotides; Polynucleotides; Ribonucleotides; RNA, Transfer; Saccharomyces cerevisiae | 1973 |
Stereoselective aminoacylation of a dinucleoside monophosphate by the imidazolides of DL-alanine and N-(tert-butoxycarbonyl)-DL-alanine.
Topics: Acylation; Alanine; Dinucleoside Phosphates; Genetic Code; Imidazoles; Inosine; Inosine Monophosphate; Inosine Nucleotides; Models, Chemical; Oligonucleotides; Stereoisomerism | 1984 |
Isolation of a human anti-haemophilic factor IX cDNA clone using a unique 52-base synthetic oligonucleotide probe deduced from the amino acid sequence of bovine factor IX.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Cattle; Cloning, Molecular; Codon; DNA; Factor IX; Hemophilia A; Humans; Liver; Oligodeoxyribonucleotides; Oligonucleotides; Species Specificity | 1983 |
Myristylation of the hepatitis B virus large surface protein is essential for viral infectivity.
Topics: Alanine; Base Sequence; Cells, Cultured; DNA, Viral; Glycine; Hepatitis B virus; Humans; Liver; Molecular Sequence Data; Myristic Acid; Myristic Acids; Oligonucleotides; Point Mutation; Protein Processing, Post-Translational; RNA, Messenger; RNA, Viral; Transfection; Tumor Cells, Cultured; Viral Envelope Proteins; Virion; Virulence; Virus Assembly | 1995 |
Alanine-scanning mutagenesis reveals residues involved in binding of pap-3-encoded pili.
Topics: Adhesins, Escherichia coli; Alanine; Amino Acid Sequence; Animals; Antigens, Bacterial; Bacterial Adhesion; Bacterial Outer Membrane Proteins; Base Sequence; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Fimbriae, Bacterial; Genes, Bacterial; Genetic Complementation Test; Hemagglutination Tests; Humans; Molecular Sequence Data; Mutagenesis; Oligonucleotides; Sheep | 1994 |
Serine319 and 321 are functional in isocitrate lyase from Escherichia coli.
Topics: Alanine; Asparagine; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression Regulation, Bacterial; Glycine; Histidine; Isocitrate Lyase; Isocitrates; Kinetics; Magnesium; Mutagenesis, Site-Directed; Oligonucleotides; Plasmids; Proline; Sequence Alignment; Serine; Threonine | 1997 |
Improving the binding affinity of an antibody using molecular modeling and site-directed mutagenesis.
Topics: Alanine; Amino Acids; Antibodies; Bacillus; Binding, Competitive; Blotting, Western; Computer Simulation; Escherichia coli; Hydrogen Bonding; Large Neutral Amino Acid-Transporter 1; Membrane Proteins; Models, Molecular; Mutagenesis, Site-Directed; Oligonucleotides; Protein Binding; Recombinant Fusion Proteins | 1998 |
Catalysis by Escherichia coli ribonuclease HI is facilitated by a phosphate group of the substrate.
Topics: Alanine; Catalysis; Escherichia coli; Histidine; Hydrolysis; Oligonucleotides; Phosphates; Recombinant Proteins; Ribonuclease H; Substrate Specificity; Thionucleotides | 2000 |
Contribution of the active site histidine residues of ribonuclease A to nucleic acid binding.
Topics: Alanine; Amino Acid Substitution; Animals; Binding Sites; Cattle; Crystallography, X-Ray; DNA; Enzyme Stability; Fluoresceins; Fluorescent Dyes; Histidine; Oligonucleotides; Protein Binding; Ribonuclease, Pancreatic; Uridine Monophosphate | 2001 |
Identification and characterization of the DNA binding domain of CpG-binding protein.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Base Sequence; Binding Sites; Blotting, Western; CpG Islands; Cysteine; DNA; DNA Methylation; Histidine; Humans; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Plasmids; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Transcriptional Activation; Zinc | 2001 |
Mutational analysis of all conserved basic amino acids in RAG-1 reveals catalytic, step arrest, and joining-deficient mutants in the V(D)J recombinase.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; DNA; DNA Nucleotidyltransferases; DNA-Binding Proteins; Genes, RAG-1; Homeodomain Proteins; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nucleic Acid Conformation; Oligonucleotides; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombination, Genetic; Transposases; VDJ Recombinases | 2002 |
R150A mutant of F TraI relaxase domain: reduced affinity and specificity for single-stranded DNA and altered fluorescence anisotropy of a bound labeled oligonucleotide.
Topics: Alanine; Arginine; Deoxyribonucleases; DNA Helicases; DNA-Binding Proteins; DNA, Single-Stranded; Escherichia coli Proteins; F Factor; Fluorescence Polarization; Hydrolysis; Mutagenesis, Site-Directed; Oligonucleotides; Protein Binding; Protein Structure, Tertiary | 2002 |
Antifungal activity of a Candida albicans GGTase I inhibitor-alanine conjugate. Inhibition of Rho1p prenylation in C. albicans.
Topics: Alanine; Alkyl and Aryl Transferases; Antifungal Agents; Candida albicans; Cells, Cultured; Enzyme Inhibitors; Fungal Proteins; Microbial Sensitivity Tests; Oligonucleotides; Protein Prenylation; rho GTP-Binding Proteins | 2003 |
Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I.
Topics: Alanine; Binding Sites; Camptothecin; Catalysis; Cell Survival; DNA; DNA Topoisomerases, Type I; Drug Resistance; Enzyme Inhibitors; Humans; Ions; Kinetics; Models, Molecular; Mutation; Oligonucleotides; Plasmids; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Time Factors; Tyrosine | 2003 |
Human RNase H1 uses one tryptophan and two lysines to position the enzyme at the 3'-DNA/5'-RNA terminus of the heteroduplex substrate.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Catalysis; Escherichia coli; Humans; Kinetics; Lysine; Models, Biological; Models, Chemical; Molecular Sequence Data; Mutation; Oligonucleotides; Plasmids; Protein Binding; Protein Structure, Tertiary; Ribonuclease H; Sequence Homology, Amino Acid; Time Factors; Tryptophan | 2003 |
Dynamic features of a heme delivery system for cytochrome C maturation.
Topics: Alanine; Amino Acid Motifs; Bacterial Outer Membrane Proteins; Bacterial Proteins; Cell Division; Cytochromes c; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Genotype; Heme; Hemeproteins; Histidine; Membrane Proteins; Models, Biological; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Periplasm; Phenotype; Plasmids; Precipitin Tests; Protein Binding; Subcellular Fractions; Tryptophan | 2003 |
Role of His-16 in turnover of T4 pyrimidine dimer glycosylase.
Topics: Alanine; Aspartic Acid; Cell Survival; Cysteine; Dimerization; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Lysine; Models, Biological; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Phenotype; Plasmids; Serine; Time Factors; Ultraviolet Rays | 2004 |
Dynamin GTPase domain mutants that differentially affect GTP binding, GTP hydrolysis, and clathrin-mediated endocytosis.
Topics: Adenoviridae; Alanine; Baculoviridae; Binding Sites; Chromatography, Gel; Clathrin; Dynamins; Endocytosis; GTP Phosphohydrolases; Guanosine Triphosphate; Humans; Hydrolysis; Kinetics; Lipids; Models, Chemical; Mutation; Oligonucleotides; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serine; Temperature; Threonine; Time Factors; Transferrin | 2004 |
Chiral-selective aminoacylation of an RNA minihelix.
Topics: Acylation; Alanine; Amino Acids; Deoxyribose; Leucine; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Oligoribonucleotides; Phenylalanine; Ribose; RNA, Transfer; RNA, Transfer, Amino Acyl; Stereoisomerism | 2004 |
Amino acids of the Sulfolobus solfataricus mini-chromosome maintenance-like DNA helicase involved in DNA binding/remodeling.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Amino Acids; Chromatography; Chromatography, Gel; Crystallography, X-Ray; Databases as Topic; DNA; DNA Helicases; Dose-Response Relationship, Drug; Escherichia coli; Histidine; Lysine; Methanobacteriaceae; Minichromosome Maintenance 1 Protein; Models, Molecular; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Oligonucleotides; Plasmids; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Sulfolobus solfataricus | 2004 |
Identification of negative residues in the P2X3 ATP receptor ectodomain as structural determinants for desensitization and the Ca2+-sensing modulatory sites.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Blotting, Western; Calcium; Cations; Cell Line; Dose-Response Relationship, Drug; Electrophysiology; Humans; Molecular Sequence Data; Mutagenesis; Mutation; Oligonucleotides; Patch-Clamp Techniques; Plasmids; Point Mutation; Protein Structure, Tertiary; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Time Factors; Transfection; Up-Regulation | 2004 |
Nuclear localization destabilizes the stress-regulated transcription factor Msn2.
Topics: Active Transport, Cell Nucleus; Alanine; Alleles; Blotting, Western; Cell Nucleus; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; DNA-Binding Proteins; Ethanol; Fungal Proteins; Genotype; Glucose; Green Fluorescent Proteins; Leupeptins; Models, Genetic; Mutation; Oligonucleotides; Oxygen Consumption; Phosphorylation; Plasmids; Promoter Regions, Genetic; Protease Inhibitors; Proteasome Inhibitors; Saccharomyces cerevisiae Proteins; Saccharomycetales; Subcellular Fractions; Time Factors; Transcription Factors; Transcription, Genetic | 2004 |
Mutation effects of a conserved alanine (Ala510) in type I polyhydroxyalkanoate synthase from Ralstonia eutropha on polyester biosynthesis.
Topics: Acyltransferases; Alanine; Amino Acid Sequence; Biopolymers; Blotting, Western; Cupriavidus necator; DNA Primers; DNA Restriction Enzymes; Escherichia coli; Molecular Sequence Data; Mutagenesis; Mutation; Oligonucleotides; Polyesters; Polymers; Sequence Homology, Amino Acid; Substrate Specificity | 2004 |
Identification of amino acids important for target recognition by the DNA:m5C methyltransferase M.NgoPII by alanine-scanning mutagenesis of residues at the protein-DNA interface.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Arginine; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; DNA; DNA Mutational Analysis; Escherichia coli; Genetic Vectors; Methyltransferases; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Mutagenesis; Mutation; Neisseria gonorrhoeae; Oligonucleotides; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Proteins; Proteomics; Sequence Homology, Amino Acid | 2005 |
Saccharomyces cerevisiae Aqr1 is an internal-membrane transporter involved in excretion of amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; beta-Galactosidase; Biological Transport; Cell Membrane; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Endocytosis; Exocytosis; Gene Expression Regulation, Fungal; Genotype; Glutamic Acid; Green Fluorescent Proteins; Homoserine; Membrane Transport Proteins; Methylamines; Microscopy, Fluorescence; Models, Biological; Monocarboxylic Acid Transporters; Mutation; Oligonucleotides; Plasmids; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Threonine; Time Factors | 2004 |
Mutational analysis of the helix-turn-helix region of Bacillus subtilis response regulator DegU, and identification of cis-acting sequences for DegU in the aprE and comK promoters.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Bacillus subtilis; Bacterial Proteins; Base Sequence; Blotting, Western; Chloramphenicol; DNA; DNA Mutational Analysis; DNA Primers; Erythromycin; Membrane Transport Proteins; Models, Genetic; Molecular Sequence Data; Mutagenesis; Mutation; Oligonucleotides; Phenotype; Phosphorylation; Plasmids; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Transcription Factors | 2004 |
The unexpected structural role of glutamate synthase [4Fe-4S](+1,+2) clusters as demonstrated by site-directed mutagenesis of conserved C residues at the N-terminus of the enzyme beta subunit.
Topics: Alanine; Amino Acid Sequence; Ammonia; Animals; Azospirillum brasilense; Cattle; Chromatography; Dihydrouracil Dehydrogenase (NADP); Dose-Response Relationship, Drug; Electron Transport; Electrons; Electrophoresis, Polyacrylamide Gel; Flavins; Glutamate Synthase; Glutarates; Imino Acids; Iron; Iron-Sulfur Proteins; Ketoglutaric Acids; Kinetics; Models, Biological; Models, Genetic; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; NADP; Oligonucleotides; Plasmids; Promoter Regions, Genetic; Protein Conformation; Protein Engineering; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrophotometry | 2005 |
Transport of the IgE receptor alpha-chain is controlled by a multicomponent intracellular retention signal.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Blotting, Western; Cell Line; Cell Membrane; Chlorocebus aethiops; COS Cells; Cytoplasm; Dimerization; Flow Cytometry; Genes, Reporter; Glycoside Hydrolases; Golgi Apparatus; Humans; Immunoprecipitation; Lysine; Microscopy, Confocal; Models, Biological; Molecular Sequence Data; Mutagenesis; Mutation; Neomycin; Oligonucleotides; Plasmids; Polymerase Chain Reaction; Protein Structure, Tertiary; Protein Transport; Receptors, IgE; Recombinant Fusion Proteins; Signal Transduction; Surface Properties; Time Factors; Transfection | 2006 |
Ggamma13 interacts with PDZ domain-containing proteins.
Topics: Alanine; Amino Acid Sequence; Animals; Blotting, Western; Brain; Cell Line; Disks Large Homolog 4 Protein; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanylate Kinases; Heterotrimeric GTP-Binding Proteins; Humans; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Lipids; Membrane Proteins; Mice; Molecular Sequence Data; Oligonucleotides; Phylogeny; Plasmids; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Signal Transduction; Taste; Two-Hybrid System Techniques | 2006 |
Functional role of catalytic triad and oxyanion hole-forming residues on enzyme activity of Escherichia coli thioesterase I/protease I/phospholipase L1.
Topics: Alanine; Asparagine; Catalytic Domain; Crystallography; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Glycine; Kinetics; Lysophospholipase; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Oligonucleotides; Periplasmic Proteins; Protein Conformation; Serine | 2006 |
Domain structure and DNA binding regions of beta protein from bacteriophage lambda.
Topics: Alanine; Amino Acid Sequence; Bacteriophage lambda; Biotinylation; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Lysine; Mass Spectrometry; Molecular Sequence Data; Oligonucleotides; Protein Binding; Protein Structure, Tertiary; Viral Proteins | 2006 |
Oligonucleotide analogs with peptide internucleotide linkages.
Topics: Alanine; Glycine; Nucleic Acid Hybridization; Oligonucleotides; Peptide Nucleic Acids; Phenylalanine | 2011 |
Identification of conserved amino acids in the herpes simplex virus type 1 UL8 protein required for DNA synthesis and UL52 primase interaction in the virus replisome.
Topics: Alanine; Amino Acid Sequence; Animals; Cricetinae; DNA; DNA Helicases; DNA Primase; Herpesvirus 1, Human; Microscopy, Fluorescence; Molecular Sequence Data; Mutagenesis; Mutation; Oligonucleotides; Plasmids; Sequence Homology, Amino Acid; Viral Proteins; Virus Replication | 2012 |
Paralogous ALT1 and ALT2 retention and diversification have generated catalytically active and inactive aminotransferases in Saccharomyces cerevisiae.
Topics: Alanine; Alanine Transaminase; Catalysis; Cell-Free System; Co-Repressor Proteins; Enzyme Activation; Evolution, Molecular; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Glucose; Models, Biological; Models, Chemical; Oligonucleotides; Phylogeny; Saccharomyces cerevisiae | 2012 |
Reliable oligonucleotide conformational ensemble generation in explicit solvent for force field assessment using reservoir replica exchange molecular dynamics simulations.
Topics: Alanine; Dipeptides; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Dynamics Simulation; Oligonucleotides; Solvents | 2013 |
Effect of Ala replacement with Aib in amphipathic cell-penetrating peptide on oligonucleotide delivery into cells.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Aminoisobutyric Acids; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Cell-Penetrating Peptides; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Hydrophobic and Hydrophilic Interactions; L-Lactate Dehydrogenase; Mice; Molecular Sequence Data; NIH 3T3 Cells; Oligonucleotides; Structure-Activity Relationship | 2013 |