alanine and niacinamide

alanine has been researched along with niacinamide in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19907 (22.58)18.7374
1990's2 (6.45)18.2507
2000's3 (9.68)29.6817
2010's15 (48.39)24.3611
2020's4 (12.90)2.80

Authors

AuthorsStudies
Tritz, GJ; Williams, MV1
Miller, SM; Moore, MJ; Walsh, CT1
Rodwell, AW1
Asatoor, AM; Navab, F1
Curzon, G; Green, AR1
Bruice, TC; Shinkai, S1
Fuji, M; Fukumoto, Y; Nagamatsu, A; Shimeno, H1
Bahnson, BJ; Chin, JK; Colby, TD; Goldstein, BM; Klinman, JP1
CONTRERAS, E; CROXATTO, R; HUIDOBRO, F1
Lamers, RJ; Schaafsma, G; van de Sandt, JJ; van der Greef, J; van Nesselrooij, JH; Venema, K; Wessels, EC1
van der Donk, WA; Woodyer, R; Zhao, H1
Kapoor, M; Mukhi, PL; Suguna, K; Surolia, A; Surolia, N1
Allen, E; Hanahan, D; Walters, IB1
Bondinell, W; Carpenter, DC; Dong, X; Jin, Q; Keller, PM; Kerns, JK; Mitchell, L; Nevins, N; Nie, H; Podolin, PL; Rahman, A; Riflade, B; Tomaszek, T; Widdowson, KL; Yamashita, DS1
Chen, L; Lei, Y; Melgiri, ND; Meng, H; Wang, Y; Xie, P; Yang, D; Zheng, P; Zhong, J; Zhou, D1
Chang, AY; Wang, M1
Agris, PF; Fanning, KD; Francis, SP; Harris, KA; Katz, J; Lacy, M; Nicholas, BD; Pagana, J; Shin, JB1
Boucher, E; Chao, Y; Cheng, AL; Decaens, T; Ezzeddine, R; Han, KH; Heo, J; Hsu, CH; Hu, TH; Jeng, LB; Johnson, PJ; Komov, D; Kudo, M; Liu, D; Lu, L; Paik, SW; Park, JW; Philip, PA; Poon, RT; Qin, S; Raoul, JL; Robles-Aviña, J; Sobhonslidsuk, A; Tak, WY; Walters, I; Xu, J; Yan, L1
Kelley, RK1
Assenat, E; Blanc, JF; Boige, V; Boucher, E; Bruix, J; Chang, C; Chao, Y; Decaens, T; Ezzeddine, R; Fartoux, L; Finn, RS; Kang, YK; Kudo, M; Lim, HY; Lin, DY; Liu, D; Llovet, JM; Mathurin, P; Park, JW; Poon, RT; Raoul, JL; Sherman, M; Tak, WY; Walters, I1
Hsieh, YC; Huang, YT; Lee, FY; Lee, KC; Lee, PC; Lee, WP; Lin, HC; Liu, RS; Tan, TW; Yang, YY; Yeh, YC1
Fan, D; Han, G; Jia, J; Qi, X1
Johnson, PJ; Llovet, JM1
Nogowski, L; Szkudelska, K; Szkudelski, T1
Bolos, D; Finn, RS1
Kalyan, A; Kulik, L; Nimeiri, H1
Costentin, C; Decaens, T; Diao, G; Duvoux, C; Katsahian, S; Laurent, A; Luciani, A; Mallat, A; Nault, JC; Nelson, AC; Pigneur, F; Tselikas, L1
Akihiro, T; Kawai, K; Makino, Y; Nishizaka, A; Sotome, I; Yoshimura, M1
Chen, K; Dai, Y; Guo, J; Jiang, H; Jiang, N; Wang, L1
Aho, VTE; Aurich, D; Bolton, EE; Cheng, T; Mollenhauer, B; Schymanski, EL; Singh, RR; Talavera Andújar, B; Wilmes, P; Zaslavsky, L1
Chen, L; Gu, J; Huang, C; Kong, Q; Lin, D; Lu, R; Wu, W1

Reviews

1 review(s) available for alanine and niacinamide

ArticleYear
Systemic therapy of hepatocellular carcinoma: current and promising.
    Clinics in liver disease, 2015, Volume: 19, Issue:2

    Topics: Alanine; Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Combined Modality Therapy; Hepatectomy; Humans; Indoles; Liver Neoplasms; Liver Transplantation; Niacinamide; Phenylurea Compounds; Preoperative Care; Proto-Oncogene Proteins c-met; Pyrroles; Signal Transduction; Sorafenib; Sunitinib; TOR Serine-Threonine Kinases; Triazines

2015

Trials

2 trial(s) available for alanine and niacinamide

ArticleYear
Brivanib versus sorafenib as first-line therapy in patients with unresectable, advanced hepatocellular carcinoma: results from the randomized phase III BRISK-FL study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Oct-01, Volume: 31, Issue:28

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Carcinoma, Hepatocellular; Double-Blind Method; Female; Follow-Up Studies; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Prognosis; Protein Kinase Inhibitors; Sorafenib; Survival Rate; Triazines; Young Adult

2013
Brivanib in patients with advanced hepatocellular carcinoma who were intolerant to sorafenib or for whom sorafenib failed: results from the randomized phase III BRISK-PS study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Oct-01, Volume: 31, Issue:28

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Carcinoma, Hepatocellular; Double-Blind Method; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Liver Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Prognosis; Protein Kinase Inhibitors; Salvage Therapy; Sorafenib; Survival Rate; Triazines; Young Adult

2013

Other Studies

28 other study(ies) available for alanine and niacinamide

ArticleYear
Studies on the modes of action of azaserine inhibition of Escherichia coli. Potentiation of phenylalanine reversal.
    The Journal of antimicrobial chemotherapy, 1977, Volume: 3, Issue:1

    Topics: Alanine; Asparagine; Azaserine; Drug Resistance, Microbial; Drug Synergism; Escherichia coli; Glutamine; Methionine; Mutation; Niacinamide; p-Fluorophenylalanine; Phenylalanine; Stereoisomerism

1977
C-terminal cysteines of Tn501 mercuric ion reductase.
    Biochemistry, 1992, Feb-18, Volume: 31, Issue:6

    Topics: Alanine; Base Sequence; Binding Sites; Catalysis; Cysteine; Escherichia coli; Kinetics; Mercuric Chloride; Mercury; Molecular Sequence Data; Mutagenesis, Site-Directed; Niacinamide; Oxidation-Reduction; Oxidoreductases; Phenotype; Spectrophotometry; Structure-Activity Relationship; Sulfhydryl Compounds; Transformation, Bacterial

1992
A defined medium for Mycoplasma strain Y.
    Journal of general microbiology, 1969, Volume: 58, Issue:1

    Topics: Alanine; Amino Acids; Culture Media; Esters; Glycerides; Glycerol; Mycoplasma; Niacinamide; Palmitic Acids; Riboflavin; Succinates; Thiamine; Thioctic Acid

1969
Studies on intestinal absorption of amino acids and a dipeptide in a case of Hartnup disease.
    Gut, 1970, Volume: 11, Issue:5

    Topics: Adult; Alanine; Amino Acids; Chromatography, Paper; Dipeptides; Female; Hartnup Disease; Histidine; Humans; Intestinal Absorption; Intestine, Small; Niacinamide; Phenylalanine; Radiography; Tryptophan

1970
The effect of tryptophan metabolites on brain 5-hydroxytryptamine metabolism.
    Biochemical pharmacology, 1970, Volume: 19, Issue:6

    Topics: Alanine; Allopurinol; Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Carboxy-Lyases; Histamine; Kynurenic Acid; Kynurenine; Male; Methanol; Methyldopa; Mixed Function Oxygenases; Niacinamide; Nicotinic Acids; Nitroglycerin; ortho-Aminobenzoates; Phenylalanine; Phenylbutyrates; Picolinic Acids; Pyridines; Pyridoxal Phosphate; Pyridoxine; Rats; Serotonin; Sulfuric Acids; Time Factors; Tryptophan; Tryptophan Oxygenase; Xanthurenates

1970
Model reactions which establish a facile reduction of pyridoxal phosphate and analogs by 1,4-dihydropyridines.
    Biochemistry, 1973, Apr-24, Volume: 12, Issue:9

    Topics: Alanine; Aldehydes; Cations, Divalent; Chemical Phenomena; Chemistry; Deuterium; Hydrogen; Hydrogen-Ion Concentration; Hydroquinones; Imines; Kinetics; Magnetic Resonance Spectroscopy; Methanol; Models, Chemical; Niacinamide; Oxidation-Reduction; Pyridines; Pyridoxal; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet

1973
Effect of combined administration of tryptophan with putative tryptophan pyrrolase inhibitors, DL-3-pyridylalanine, allopurinol or nicotinamide, on brain serotonin concentration.
    Chemical & pharmaceutical bulletin, 1984, Volume: 32, Issue:6

    Topics: Alanine; Allopurinol; Animals; Brain Chemistry; Liver; Male; Niacinamide; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tryptophan Oxygenase

1984
Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes.
    Biochemistry, 1998, Jun-30, Volume: 37, Issue:26

    Topics: Alanine; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Binding Sites; Coenzymes; Crystallography, X-Ray; Horses; Ligands; Liver; Models, Molecular; NAD; Niacinamide; Phenylalanine; Structure-Activity Relationship; Substrate Specificity; Tryptophan; Valine

1998
STUDIES ON MORPHINE. IV. EFFECTS OF SOME METABOLITES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
    Archives internationales de pharmacodynamie et de therapie, 1963, Dec-01, Volume: 146

    Topics: Alanine; Cyanides; Fluoroacetates; Glutamine; Iodoacetates; Mice; Morphine; NAD; Nalorphine; Niacin; Niacinamide; Pharmacology; Pyridines; Pyridoxine; Research; Serine; Toxicology; Tryptophan

1963
A pilot study to investigate effects of inulin on Caco-2 cells through in vitro metabolic fingerprinting.
    The Journal of nutrition, 2003, Volume: 133, Issue:10

    Topics: Alanine; Analysis of Variance; Caco-2 Cells; Colon; Fermentation; Glucose; Glutamic Acid; Humans; Inulin; Ketoglutaric Acids; Lactic Acid; Magnetic Resonance Spectroscopy; Niacin; Niacinamide; Proline; Succinic Acid

2003
Relaxing the nicotinamide cofactor specificity of phosphite dehydrogenase by rational design.
    Biochemistry, 2003, Oct-14, Volume: 42, Issue:40

    Topics: Alanine; Amino Acid Sequence; Chromatography, High Pressure Liquid; Computer Simulation; Enzyme Stability; Escherichia coli Proteins; Glutamic Acid; Hot Temperature; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NADH, NADPH Oxidoreductases; NADP; Niacinamide; Protein Engineering; Sequence Homology, Amino Acid; Substrate Specificity; Thermodynamics

2003
Kinetic and structural analysis of the increased affinity of enoyl-ACP (acyl-carrier protein) reductase for triclosan in the presence of NAD+.
    The Biochemical journal, 2004, Aug-01, Volume: 381, Issue:Pt 3

    Topics: Alanine; Animals; Asparagine; Carbon-Carbon Ligases; Cloning, Molecular; Crystallography, X-Ray; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); NAD; Niacinamide; Oxidoreductases; Plasmodium falciparum; Protein Binding; Structure-Activity Relationship; Substrate Specificity; Surface Plasmon Resonance; Triclosan

2004
Brivanib, a dual FGF/VEGF inhibitor, is active both first and second line against mouse pancreatic neuroendocrine tumors developing adaptive/evasive resistance to VEGF inhibition.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Aug-15, Volume: 17, Issue:16

    Topics: Alanine; Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Blotting, Western; Drug Resistance, Neoplasm; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Mice; Mice, Knockout; Mice, Transgenic; Neuroendocrine Tumors; Niacinamide; Pancreatic Neoplasms; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Receptors, Fibroblast Growth Factor; Sorafenib; Treatment Outcome; Triazines; Tumor Burden; Vascular Endothelial Growth Factor Receptor-2

2011
Azepanone-based inhibitors of human cathepsin S: optimization of selectivity via the P2 substituent.
    Bioorganic & medicinal chemistry letters, 2011, Aug-01, Volume: 21, Issue:15

    Topics: Alanine; Azepines; Binding Sites; Cathepsin K; Cathepsin L; Cathepsins; Computer Simulation; Humans; Niacinamide; Protease Inhibitors; Stereoisomerism; Structure-Activity Relationship

2011
Identification and validation of urinary metabolite biomarkers for major depressive disorder.
    Molecular & cellular proteomics : MCP, 2013, Volume: 12, Issue:1

    Topics: Adult; Alanine; Biomarkers; Depressive Disorder, Major; Female; Formates; Homovanillic Acid; Humans; Male; Malonates; Metabolome; Metabolomics; Niacinamide; Nuclear Magnetic Resonance, Biomolecular; Phenylacetates

2013
In-vitro growth inhibition of chemotherapy and molecular targeted agents in hepatocellular carcinoma.
    Anti-cancer drugs, 2013, Volume: 24, Issue:3

    Topics: Alanine; alpha-Fetoproteins; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma, Hepatocellular; Cetuximab; Dasatinib; Doxorubicin; Drug Screening Assays, Antitumor; Epothilones; Gefitinib; Humans; Indoles; Inhibitory Concentration 50; Liver Neoplasms; Niacinamide; Phenylurea Compounds; Piperidines; Pyridones; Pyrimidines; Pyrroles; Quinazolines; Sorafenib; Sunitinib; Thiazoles; Triazines

2013
A novel role of cytosolic protein synthesis inhibition in aminoglycoside ototoxicity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Feb-13, Volume: 33, Issue:7

    Topics: Alanine; Alkynes; Aminoglycosides; Animals; Anti-Bacterial Agents; Apoptosis; Blotting, Western; Cell Count; Chick Embryo; Cytosol; Ear Diseases; Enzyme Activation; Evoked Potentials, Auditory, Brain Stem; Glycine; Hair Cells, Auditory; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred CBA; Niacinamide; Organ Culture Techniques; Phenylurea Compounds; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; RNA, Ribosomal; Sorafenib

2013
Brivanib and FOLFOX in hepatocellular carcinoma: finding the common themes among negative trials.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Oct-01, Volume: 31, Issue:28

    Topics: Alanine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Drug Resistance, Neoplasm; Female; Humans; Liver Neoplasms; Male; Niacinamide; Palliative Care; Phenylurea Compounds; Protein Kinase Inhibitors; Salvage Therapy; Sorafenib; Triazines

2013
Anti-VEGFR agents ameliorate hepatic venous dysregulation/microcirculatory dysfunction, splanchnic venous pooling and ascites of NASH-cirrhotic rat.
    Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34, Issue:4

    Topics: Alanine; Animals; Ascites; Cytokines; DNA Primers; Fatty Liver; Fibroblast Growth Factors; Microcirculation; Niacinamide; Non-alcoholic Fatty Liver Disease; Phenylurea Compounds; Platelet-Derived Growth Factor; Positron-Emission Tomography; Rats; Receptors, Vascular Endothelial Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; Sorafenib; Splanchnic Circulation; Triazines; Vascular Endothelial Growth Factor A

2014
Brivanib for hepatocellular carcinoma trials: selection bias from barcelona clinic liver cancer stage?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Mar-20, Volume: 32, Issue:9

    Topics: Alanine; Carcinoma, Hepatocellular; Drug Resistance, Neoplasm; Female; Humans; Liver Neoplasms; Male; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Salvage Therapy; Triazines

2014
Reply to X. Qi et al.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Mar-20, Volume: 32, Issue:9

    Topics: Alanine; Carcinoma, Hepatocellular; Drug Resistance, Neoplasm; Female; Humans; Liver Neoplasms; Male; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Salvage Therapy; Triazines

2014
Adipocyte dysfunction in rats with streptozotocin-nicotinamide-induced diabetes.
    International journal of experimental pathology, 2014, Volume: 95, Issue:2

    Topics: Adipocytes; Adipose Tissue; Alanine; Animals; Diabetes Mellitus, Experimental; Glucose; Lipogenesis; Lipolysis; Niacinamide; Rats; Streptozocin

2014
Systemic therapy in HCC: lessons from brivanib.
    Journal of hepatology, 2014, Volume: 61, Issue:4

    Topics: Alanine; Carcinoma, Hepatocellular; Drug Resistance, Neoplasm; Female; Humans; Liver Neoplasms; Male; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Salvage Therapy; Triazines

2014
Visceral fat area predicts survival in patients with advanced hepatocellular carcinoma treated with tyrosine kinase inhibitors.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2015, Volume: 47, Issue:10

    Topics: Aged; Alanine; alpha-Fetoproteins; Carcinoma, Hepatocellular; Female; France; Hand-Foot Syndrome; Humans; Intra-Abdominal Fat; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Niacinamide; Phenylurea Compounds; Prognosis; Protein Kinase Inhibitors; Retrospective Studies; Sarcopenia; Sorafenib; Survival Rate; Tomography, X-Ray Computed; Triazines

2015
Influence of low O
    Food chemistry, 2020, Jul-01, Volume: 317

    Topics: Alanine; Atmosphere; Carbon Dioxide; Cluster Analysis; Color; Food Packaging; Food Storage; Glycine max; Inositol; Metabolomics; Micronutrients; Multivariate Analysis; Niacinamide; Oxygen; Seeds; Time Factors; Vegetables

2020
Characterization of nitrilases from Variovorax boronicumulans that functions in insecticide flonicamid degradation and β-cyano-L-alanine detoxification.
    Journal of applied microbiology, 2022, Volume: 133, Issue:2

    Topics: Alanine; Aminohydrolases; Comamonadaceae; Escherichia coli; Insecticides; Niacinamide

2022
Studying the Parkinson's disease metabolome and exposome in biological samples through different analytical and cheminformatics approaches: a pilot study.
    Analytical and bioanalytical chemistry, 2022, Volume: 414, Issue:25

    Topics: Aged; Alanine; Betaine; Cheminformatics; Exposome; Humans; Metabolome; Metabolomics; Neurodegenerative Diseases; Niacinamide; Parkinson Disease; Pilot Projects

2022
NMR-Based Metabolomic Analysis of Cardiac Tissues Clarifies Molecular Mechanisms of CVB3-Induced Viral Myocarditis and Dilated Cardiomyopathy.
    Molecules (Basel, Switzerland), 2022, Sep-19, Volume: 27, Issue:18

    Topics: Alanine; Animals; Aspartic Acid; Biomarkers; Cardiomyopathy, Dilated; Coxsackievirus Infections; Enterovirus B, Human; Glutamic Acid; Glutamine; Glycine; Mice; Mice, Inbred BALB C; Myocarditis; Niacin; Niacinamide; Serine; Taurine; Threonine

2022