alanine has been researched along with nadp in 96 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 53 (55.21) | 18.7374 |
| 1990's | 19 (19.79) | 18.2507 |
| 2000's | 16 (16.67) | 29.6817 |
| 2010's | 8 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Desai, JD; Modi, VV | 1 |
| Akiyoshi, H; Fujii, S; Minato, Y; Okuda, H; Toide, H | 1 |
| Karpilova, IF; Kerimov, S | 1 |
| Stumpf, PK | 1 |
| Goldberg, DM; Holme, DJ | 1 |
| Lin, MC; Wagner, C | 1 |
| Buc-Calderon, P; Roberfroid, M | 1 |
| Kanamori, K; Roberts, JD; Weiss, RL | 1 |
| Baron, P; Griffaton, G; Lowy, R | 5 |
| Kopwillem, A | 1 |
| McCowen, SM; Phibbs, PV | 1 |
| Dade, E; Elliott, J; Hems, DA; Salmon, DM | 1 |
| Silverstein, E; Sulebele, G | 1 |
| Podack, ER; Seubert, W | 1 |
| Brosnan, JT; Williamson, DH | 1 |
| Cornell, NW; Krebs, HA; Lund, P | 1 |
| Ziegler, H; Ziegler, I | 1 |
| Von Korff, RW | 1 |
| Gottlieb, D; Inoue, Y | 1 |
| Kapoor, M; Smith, DW | 1 |
| Favarger, P; Giacobino, JP | 1 |
| Deodhar, AD; Mistry, SP | 1 |
| Browning, ET; Scholz, R; Williamson, JR | 1 |
| Browning, ET; Fukami, MH; Scholz, R; Thurman, RG; Williamson, JR | 1 |
| Ardouin, B; Baron, P; Doucet, C; Griffaton, G; Lowy, R | 1 |
| Coles, GC | 1 |
| Santarius, KA; Stocking, CR | 1 |
| Kagan, ZS; Kretovich, WL; Polyakov, WA | 1 |
| Haddad, V; Jacobs, AA; Mitchell, GW; Paul, BB; Sbarra, AJ; Strauss, RR | 1 |
| Chamalaun, RA; Tager, JM | 1 |
| Cano, A; Mayor, F; Nuñez de Castro, I; Ugarte, M | 1 |
| Jákob, A; Scholz, R; Williamson, JR | 1 |
| Black, CC; Lee, SS; Travis, J | 1 |
| Garfinkel, D | 1 |
| Bott, KF | 1 |
| Cohen, R; Mire, M | 1 |
| Moat, AG; Thomulka, KW | 1 |
| Elmerich, C | 1 |
| Karl, IE; Kipnis, DM; Pagliara, AS | 1 |
| Bergquist, A; LaBrie, DA; Leiter, EH; Wagner, RP | 1 |
| Boveris, A; Chance, B; Oshino, N | 1 |
| DeLuca, M; Wienhausen, G | 1 |
| Bernard, N; Delcour, J; Holbrook, JJ; Johnsen, K | 1 |
| Hachtel, W; Schöndorf, T | 1 |
| Andrews, J; Arnold, JR; Basran, J; Birdsall, B; Feeney, J; Roberts, GC; Thomas, JA | 1 |
| Arscott, LD; Berry, A; Deonarain, MP; Perham, RN; Rietveld, P; Scrutton, NS; Williams, CH | 1 |
| Baker, ME; Chang, SH; Chen, Z; Lee, WR; Tsigelny, I | 1 |
| Décout, JL; Fieschi, F; Fontecave, M; Nivière, V | 1 |
| Arscott, LD; Bashir, A; Berry, A; Perham, RN; Williams, CH | 1 |
| Bryant, DA; Golbeck, JH; Jung, YS; Qiao, F; Vassiliev, IR; Yang, F | 1 |
| Cadenas, E; Forman, HJ; Qiu, X; Schönthal, AH | 1 |
| Perrottet, P; Poitry, S; Poitry-Yamate, CL; Tsacopoulos, M; Veuthey, AL | 1 |
| Marrone, L; Viswanatha, T | 1 |
| Beninger, RJ; Boegman, RJ; Harris, CA; Jhamandas, K; Miranda, AF; Tanguay, JJ | 1 |
| Engst, S; Miller, SM | 1 |
| Gómez-Moreno, C; Hermoso, J; Hurley, JK; Martínez-Júlvez, M; Mayoral, T; Medina, M; Sanz-Aparicio, J; Tollin, G | 1 |
| Alzari, PM; Betzel, C; Fita, I; Herzog, C; Koller, F; Maté, MJ; Nykyri, LM; Zamocky, M | 1 |
| Arscott, LD; Gilberger, TW; Müller, S; Wang, PF; Williams, CH | 1 |
| Fita, I; Loewen, PC; Maté, MJ; Sevinc, MS; Switala, J | 1 |
| Ganago, AO; Golbeck, JH; Jung, YS; McIntosh, L; Schulz, R; Vassiliev, IR; Yu, J | 1 |
| Colombo, C; Curti, B; Morandi, P; Valzasina, B; Vanoni, MA | 1 |
| Barber, MJ; Pollock, VV | 1 |
| Doehr, O; Gutierrez, A; Paine, M; Roberts, GC; Scrutton, NS; Wolf, CR | 1 |
| Sciotti, M; Wermuth, B | 1 |
| Anderson, S; Banta, S; Jarnagin, A; Swanson, BA; Wu, S | 1 |
| Berndt, KD; Chiaraluce, R; Consalvi, V; Ladenstein, R; Lebbink, JH | 1 |
| Stout, CD; Yamaguchi, M | 1 |
| MARQUET, M | 1 |
| POMEROY, LR; ROACH, MK; SIEGEL, FL | 1 |
| BITENSKY, MW; TALAL, N; TOMKINS, GM; YIELDING, KL | 1 |
| JONES, RF; KATES, JR | 1 |
| DIVEN, WF; JOHNSTON, RB; SCHOLZ, JJ | 1 |
| BITENSKY, MW; TOMKINS, GM; YIELDING, KL | 1 |
| CAMPBELL, JW; PRESCOTT, LM | 1 |
| SORGER, GJ | 1 |
| van der Donk, WA; Woodyer, R; Zhao, H | 1 |
| Daff, S | 1 |
| Cooper, WC; Heredia, VV; Jin, Y; Kruger, RG; Penning, TM | 1 |
| Munro, AW; Neeli, R; Roitel, O; Scrutton, NS | 1 |
| Bohren, KM; Brownlee, JM; Gabbay, KH; Harrison, DH; Milne, AC | 1 |
| Agnelli, P; Colombi, P; Curti, B; Dossena, L; Morandi, P; Mulazzi, S; Negri, A; Tedeschi, G; Vanoni, MA | 1 |
| González-Segura, L; Mújica-Jiménez, C; Muñoz-Clares, RA; Velasco-García, R; Zaldívar-Machorro, VJ | 1 |
| Gao, YT; Martásek, P; Masters, BS; Panda, SP; Roman, LJ; Salerno, JC | 1 |
| Ilg, T; Jaeger, M; Rothacker, B | 1 |
| Dickert, F; Dobbek, H; Knauer, SH; Mende, S; Spiegelhauer, O; Ullmann, GM | 1 |
| Benkovic, SJ; Kohen, A; Lee, J; Perissinotti, LL; Stojković, V | 1 |
| Dang, Z; Liu, D; Shen, Z; Wang, X; Xu, X; Zhang, P; Zhou, Z; Zhu, W | 1 |
| Gan, J; Gong, J; Humphreys, WG; Iyer, RA; Jemal, M; Masson, E; Pursley, J; Syed, S; Williams, D; Xia, YQ | 1 |
| Echandi, MP; Ellerbrock, J; Fedkenheuer, M; Franceschini, S; Martin Del Campo, JS; Robinson, R; Rodriguez, PJ; Romero, E; Sobrado, P | 1 |
| Cabrera, R; Fuentealba, M; Krapp, A; Maturana, P; Muñoz, R | 1 |
| Louder, A; Meints, CE; Mothersole, RG; Wolthers, KR | 1 |
| Li, Y; Wang, C; Wang, X; Zhang, H | 1 |
2 review(s) available for alanine and nadp
| Article | Year |
|---|---|
Phytoenzyme systems as models for an understanding of general metabolic pathways.
Topics: Acetyl Coenzyme A; Alanine; Animals; Biotin; Carboxy-Lyases; Carrier Proteins; Chloroplasts; Coenzyme A; Fatty Acid Desaturases; Fatty Acids; Fatty Acids, Nonesterified; Humans; Linolenic Acids; Lipids; NADP; Oleic Acids; Oxidation-Reduction; Photosynthesis; Plants; Propionates; Refsum Disease; Stearic Acids | 1975 |
Mechanisms and physiological roles of fatty acid chain elongation in microsomes and mitochondria.
Topics: Acetates; Acetyl Coenzyme A; Alanine; Animals; Aorta; Arteriosclerosis; Caproates; Carbon Radioisotopes; Cattle; Centrifugation, Zonal; Citric Acid Cycle; Coenzyme A; Fatty Acids, Unsaturated; Gluconeogenesis; Glutamates; Linolenic Acids; Liver; Malonates; Microsomes, Liver; Mitochondria, Liver; Myocardium; NAD; NADP; Oxidoreductases; Rats; Thermodynamics | 1973 |
94 other study(ies) available for alanine and nadp
| Article | Year |
|---|---|
Assimilation of ammonia and growth of biotin deficient Aspergillus nidulans.
Topics: Alanine; Amino Acid Oxidoreductases; Ammonia; Aspergillus nidulans; Avitaminosis; Biotin; Glutamate Dehydrogenase; Glutamate Synthase; Glutamate-Ammonia Ligase; NAD; NADP | 1976 |
Comparative studies on the metabolism of 2-(tetrahydrofuryl)-5-fluorouracil and 5-fluorouracil.
Topics: Alanine; Animals; DNA, Neoplasm; Fluorouracil; In Vitro Techniques; Male; Mice; Microsomes, Liver; NADP; Neoplasms, Experimental; Nucleic Acid Precursors; Rats; Tegafur; Tissue Distribution | 1977 |
[Role of pyruvate kinase in non-specific changes of carbon photosynthetic metabolism, caused by the photophosphorylation inhibition].
Topics: Alanine; Carbon Dioxide; Chloroplasts; NADP; Paraquat; Photophosphorylation; Pyruvate Kinase; Vitamin K | 1978 |
Coupled optical rate determinations of amino acid oxidase activity.
Topics: Alanine; Amino Acid Oxidoreductases; Animals; D-Amino-Acid Oxidase; Glutamate Dehydrogenase; Kidney; Kinetics; Leucine; Manometry; Methods; NAD; NADP; Spectrophotometry; Swine | 1975 |
Purification and characterization of N-methylalanine dehydrogenase.
Topics: Alanine; Amino Acid Oxidoreductases; Chromatography, DEAE-Cellulose; Chromatography, Gel; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; NADP; Oxidation-Reduction; Pseudomonas; Structure-Activity Relationship | 1975 |
AD 5, a dehydroalanine derivative, decreases the amount of reactive oxygen species formed during nitrofurantion microsomal metabolism.
Topics: Alanine; Animals; Hydrogen Peroxide; Kinetics; Male; Microsomes, Liver; NADP; Nitrofurantoin; Oxygen Consumption; Rats; Rats, Inbred Strains; Superoxides | 1990 |
Ammonia assimilation in Bacillus polymyxa. 15N NMR and enzymatic studies.
Topics: Alanine; Alanine Dehydrogenase; Alanine Transaminase; Amino Acid Oxidoreductases; Ammonia; Bacillus; Glutamate Dehydrogenase; Glutamate Synthase; Glutamates; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; NADP; Nitrates; Nitrogen Fixation | 1987 |
[Effect of a pyruvate injection on liver metabolism in the rat].
Topics: Acetone; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; Citrates; Glutamates; Glycerophosphates; Ketoglutaric Acids; Liver; Male; Metabolism; Models, Chemical; NADP; Phosphates; Phosphoric Acids; Pyruvates; Rats; Time Factors; Trioses; Urea | 1971 |
[Effect of the simultaneous administration of pyruvate and ethanol on liver metabolism in the rat].
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; Citrates; Drug Synergism; Ethanol; Glutamates; Ketoglutaric Acids; Liver; Male; Metabolism; Models, Chemical; NADP; Oxidation-Reduction; Phosphates; Pyruvates; Rats; Time Factors; Urea | 1971 |
Analytical isotachophoresis in capillary tubes used for the separation of ions involved in the enzymatic transformation of glucose to 6-phosphogluconate.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Electrophoresis; Gluconates; Glucose; Glucosephosphates; Hydrochloric Acid; Hydrogen-Ion Concentration; Methods; NADP; Spectrophotometry, Ultraviolet | 1973 |
Regulation of alanine dehydrogenase in Bacillus (licheniformis).
Topics: Alanine; Amino Acid Oxidoreductases; Ammonium Chloride; Ammonium Sulfate; Bacillus; Cell-Free System; Chemical Precipitation; Chromatography, DEAE-Cellulose; Glucose; Glutamates; Malates; NAD; NADP; Pyruvates; Spectrophotometry; Spores, Bacterial; Stereoisomerism; Time Factors | 1974 |
Hepatic metabolism in normal and genetically obese mice.
Topics: Alanine; Amino Acids; Animals; Blood Glucose; Carbon Radioisotopes; Citrates; Female; Gluconeogenesis; Glucosephosphates; Glycerol; Glycerophosphates; Glycogen; Heterozygote; Homozygote; Lactates; Lipids; Liver; NADP; Obesity; Starvation; Triglycerides | 1974 |
Equilibrium kinetic study of the catalytic mechanism of oxidative deamination of alanine by bovine liver glutamate dehydrogenase.
Topics: Alanine; Animals; Binding Sites; Carbon Radioisotopes; Catalysis; Cattle; Deamination; Glutamate Dehydrogenase; Glutamates; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; Liver; Models, Chemical; NAD; NADP; Oxidation-Reduction; Pyruvates | 1974 |
Mechanisms for the formation of alanine and aspartate on rat liver in vivo after administration of ammonium chloride.
Topics: Alanine; Alanine Transaminase; Ammonia; Ammonium Chloride; Animals; Arginine; Aspartic Acid; Centrifugation; Cycloserine; Ketoglutaric Acids; Liver; Male; NAD; NADP; Rats; Time Factors; Urea | 1974 |
The effect of lysine on gluconeogenesis from lactate in rat hepatocytes.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Female; Gluconeogenesis; Glucose; Glutamates; Lactates; Liver; Lysine; Mitochondria, Liver; NADP; Oxaloacetates; Pyruvate Carboxylase; Pyruvates; Rats | 1974 |
[The light-induced increase in the activity of NADP+-dependent glyceraldehyde-3-phosphate dehydrogenase. IV. Influence on the intensity of the photosynthesis].
Topics: Alanine; Amino Acids; Chloramphenicol; Enzymes; Ethionine; Feedback; Light; Methionine; NADP; Phenylalanine; Photosynthesis; Plants | 1966 |
Substrate transformations dependent on respiratory states of mitochondria. Changes in metabolic control sites of rabbit heart mitochondria.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Alanine; Animals; Carbon Isotopes; Citrates; Dinitrophenols; Glutamates; Hydroxybutyrates; Malates; Mitochondria; Myocardium; NAD; NADP; Oxaloacetates; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Pyruvates; Rabbits; Succinates | 1967 |
Flavensomycin, an inhibitor of enzyme reactions involving hydrogen transfer.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acid Oxidoreductases; Antifungal Agents; Cytochromes; D-Amino-Acid Oxidase; Electron Transport; Flavin-Adenine Dinucleotide; Glucose Oxidase; Hexokinase; Isocitrate Dehydrogenase; L-Lactate Dehydrogenase; Leucine; NAD; NADP; Oxidoreductases; Penicillium; Phenylalanine; Pyruvates | 1967 |
Some unusual mutants of a locus related to the am locus in Neurospora.
Topics: Alanine; Genetics, Microbial; Glutamate Dehydrogenase; Hydrogen-Ion Concentration; Mutation; NAD; NADP; Neurospora | 1968 |
[Effect of fasting and insulin on lipogenesis and gluconeogenesis from amino acids in living mice].
Topics: Acetoacetates; Alanine; Animals; Carbon Isotopes; Fasting; Fatty Acids; Female; Gluconeogenesis; Insulin; Leucine; Liver; Mice; NAD; NADP; Oleic Acids; Palmitic Acids; Stearic Acids; Stereoisomerism; Stimulation, Chemical; Tritium | 1968 |
Control of gluconeogenesis in biotin-deficient rat liver.
Topics: Alanine; Animals; Aspartic Acid; Avitaminosis; Bicarbonates; Biotin; Blood Glucose; Carbon Isotopes; Fatty Acids, Nonesterified; Gluconeogenesis; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycerol; Lactates; Ligases; Liver; Liver Glycogen; Male; NAD; NADP; Pyruvates; Rats; Succinates; Time Factors | 1969 |
Control mechanisms of gluconeogenesis and ketogenesis. I. Effects of oleate on gluconeogenesis in perfused rat liver.
Topics: Alanine; Animals; Coenzyme A; Fatty Acids, Nonesterified; Fructose-Bisphosphatase; Gluconeogenesis; Glyceraldehyde-3-Phosphate Dehydrogenases; In Vitro Techniques; Ketone Bodies; Lactates; Ligases; Liver; Liver Glycogen; Male; Mitochondria, Liver; Models, Biological; NAD; NADP; Oleic Acids; Perfusion; Phosphofructokinase-1; Pyruvates; Rats; Stimulation, Chemical; Time Factors; Trioses | 1969 |
[Effects of an intraperitoneal injection of ethanol on liver metabolism of the rat].
Topics: Alanine; Animals; Aspartic Acid; Citrates; Ethanol; Glutamates; Glycolysis; Injections, Intraperitoneal; Ketoglutaric Acids; Liver; Male; NADP; Rats | 1969 |
Metabolic effects of ethanol in perfused rat liver.
Topics: Acetates; Adenine Nucleotides; Alanine; Animals; Citric Acid Cycle; Coenzyme A; Depression, Chemical; Ethanol; Fatty Acids; Flavins; Fluorometry; Gluconeogenesis; Hydrogen; In Vitro Techniques; Isocitrate Dehydrogenase; Ketone Bodies; Liver; Lyases; Male; NAD; NADP; Oleic Acids; Oxygen Consumption; Perfusion; Phosphofructokinase-1; Polarography; Rats; Stimulation, Chemical | 1969 |
[Determination of substrate concentrations and cofactors in rat liver].
Topics: Acetoacetates; Alanine; Animals; Aspartic Acid; Citrates; Citric Acid Cycle; Glutamates; Glycerophosphates; Hydroxybutyrates; Ketoglutaric Acids; Lactates; Liver; Malates; NAD; NADP; Oxaloacetates; Pyruvates; Rats; Trioses | 1969 |
Isoenzymes of snail livers. II. Dehydrogenases.
Topics: Alanine; Amino Acid Oxidoreductases; Animals; Ecology; Electrophoresis; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; Glycerolphosphate Dehydrogenase; Hydroxybutyrate Dehydrogenase; Isocitrate Dehydrogenase; Isoenzymes; L-Lactate Dehydrogenase; Liver; Malate Dehydrogenase; NAD; NADP; Oxidoreductases; Phosphogluconate Dehydrogenase; Snails; Trematoda | 1969 |
Intracellular localization of enzymes in leaves and chloroplast membrane permeability to compounds involved in amino acid syntheses.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acid Oxidoreductases; Amino Acids; Aspartate Aminotransferases; Aspartic Acid; Carbon Dioxide; Chloroplasts; Glutamate Dehydrogenase; Glutamates; Glutathione Reductase; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycine; Isocitrate Dehydrogenase; Malate Dehydrogenase; NAD; NADP; Nicotiana; Oxidoreductases; Plants; Plants, Edible; Plants, Toxic; Pyruvate Kinase; Serine | 1969 |
Further studies on plant valine dehydrogenase.
Topics: Alanine; Chromatography, Gel; Glutamate Dehydrogenase; Hydrogen-Ion Concentration; Hydroxylamines; Keto Acids; Kinetics; Leucine; NADP; Oxidoreductases; Plant Cells; Plants; Ultracentrifugation; Valine | 1970 |
The role of the phagocyte in host-parasite interactions. XXV. Metabolic and bactericidal activities of leukocytes from pregnant women.
Topics: Alanine; Animals; Bacteriuria; Blood Bactericidal Activity; Carbon Isotopes; Carboxy-Lyases; Escherichia coli; Female; Glucose; Guinea Pigs; Hexosephosphates; Humans; Leukocytes; NADP; Oxidation-Reduction; Peroxidases; Phagocytosis; Pregnancy | 1970 |
Nitrogen metabolism in the perfused rat liver.
Topics: Alanine; Ammonia; Ammonium Chloride; Animals; Aspartic Acid; Glutamate Dehydrogenase; Glutamates; Glutamine; Hydroxybutyrate Dehydrogenase; Liver; NAD; NADP; Nitrogen; Perfusion; Rats; Stimulation, Chemical; Urea | 1970 |
Effect of glucose, galactose, and different nitrogen-sources on the activity of yeast glutamate dehydrogenase (NAD and NADP-linked) from normal strain and impaired respiration mutant.
Topics: Alanine; Ammonia; Galactose; Glucose; Glutamate Dehydrogenase; Glutamates; Methods; Mutation; NAD; NADP; Nitrogen; Saccharomyces | 1970 |
[Effects of simultaneous i. p. injection of fructose and ethanol on hepatic metabolism in the rat].
Topics: Alanine; Animals; Aspartic Acid; Citrates; Ethanol; Fasting; Fructose; Glutamates; Glycolysis; Injections, Intraperitoneal; Ketoglutaric Acids; Liver; Male; NADP; Oxidoreductases; Rats | 1970 |
Energy cost of gluconeogenesis in rat liver.
Topics: Adenosine Triphosphate; Alanine; Animals; Citrates; Ethanol; Fructose; Gluconeogenesis; Hexosephosphates; Ligases; Liver; Mitochondria, Liver; NAD; NADP; Oxaloacetates; Oxidative Phosphorylation; Oxygen Consumption; Perfusion; Phosphofructokinase-1; Phosphoric Acids; Pyruvate Kinase; Pyruvates; Rats; Starvation; Xylitol | 1971 |
[Effects of an intraperitoneal injection of fructose on the hepatic metabolism of the rat].
Topics: Alanine; Animals; Aspartic Acid; Citrates; Citric Acid Cycle; Fasting; Fructose; Glutamates; Glycolysis; Injections, Intraperitoneal; Ketoglutaric Acids; Lipids; Liver; Malates; Male; NAD; NADP; Oxaloacetates; Rats; Stimulation, Chemical; Time Factors; Transaminases | 1970 |
Characterization of ferredoxin from nutsedge, Cyperus rotundus L., and other species with a high photosynthetic capacity.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Bacteria; Biological Evolution; Carbon Dioxide; Chlorophyll; Chloroplasts; Cytochromes; Dicarboxylic Acids; Electron Spin Resonance Spectroscopy; Electrophoresis, Disc; Ferredoxins; Glycine; Hydrogen-Ion Concentration; Iron; Molecular Weight; NADP; Pentosephosphates; Peptides; Photochemistry; Photosynthesis; Plant Proteins; Plants; Serine; Species Specificity; Spectrophotometry; Sulfur | 1970 |
Simulation of the Krebs cycle and closely related metabolism in perfused rat liver. I. Construction of a model.
Topics: Adenine Nucleotides; Alanine; Animals; Citric Acid Cycle; Coenzyme A; Cytoplasm; Glutamate Dehydrogenase; Isocitrate Dehydrogenase; Ligases; Liver; Mitochondria, Liver; Models, Biological; NAD; NADP; Nucleotides; Oleic Acids; Perfusion; Pyridines; Rats | 1971 |
Acrylamide gel electrophoresis of intracellular proteins during early stages of sporulation in Bacillus subtilis.
Topics: Alanine; Alcohol Oxidoreductases; Alkaline Phosphatase; Amino Acid Oxidoreductases; Bacillus subtilis; Bacterial Proteins; Cell-Free System; Electrophoresis, Disc; Esterases; Fructose-Bisphosphate Aldolase; Glucose; Glutamate Dehydrogenase; Hexokinase; Histocytochemistry; Malate Dehydrogenase; Methods; NAD; NADP; Oxidoreductases; Peptide Hydrolases; Picolinic Acids; Spectrophotometry; Spores; Spores, Bacterial | 1971 |
Analytical-band centrifugation of an active enzyme-substrate complex. 2. Determination of active units of various enzymes.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acid Oxidoreductases; Animals; Aspartate-Semialdehyde Dehydrogenase; Cattle; Escherichia coli; Galactosidases; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; L-Lactate Dehydrogenase; Liver; Macromolecular Substances; Methods; Muscles; NAD; NADP; Rabbits; Saccharomyces cerevisiae; Ultracentrifugation | 1971 |
Inorganic nitrogen assimilation in yeasts: alteration in enzyme activities associated with changes in cultural conditions and growth phase.
Topics: Alanine; Alanine Transaminase; Amino Acid Oxidoreductases; Amino Acids; Ammonium Sulfate; Aspartate Aminotransferases; Aspartic Acid; Cell-Free System; Culture Media; Electrophoresis, Disc; Genetics, Microbial; Glucose; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Hydro-Lyases; Hydrogen-Ion Concentration; Lyases; Mutation; NAD; NADP; Nitrogen; Saccharomyces; Saccharomyces cerevisiae; Spectrophotometry; Threonine; Transaminases | 1972 |
[Glutamate cycle, first step of nitrogen metabolism in Bacillus megaterium].
Topics: Alanine; Allosteric Regulation; Amino Acid Oxidoreductases; Ammonia; Aspartic Acid; Bacillus megaterium; Enzyme Repression; Glucose; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Ketoglutaric Acids; Lyases; Mutation; NAD; NADP; Nitrogen; Oxaloacetates; Oxidoreductases; Pyruvates; Transaminases | 1972 |
A microfluorometric enzymatic assay for the determination of alanine and pyruvate in plasma and tissues.
Topics: Alanine; Alanine Transaminase; Animals; Centrifugation; Filtration; Fluorometry; Humans; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kidney; L-Lactate Dehydrogenase; Liver; Male; Methods; Muscles; NADP; Perchlorates; Pyruvates; Rats; Temperature; Time Factors; Ultracentrifugation | 1972 |
Synthesis of amino acids from succinate by the mitochondria of Neurospora crassa.
Topics: Adenosine Diphosphate; Alanine; Carbon Isotopes; Glucosephosphates; Glutamates; Malate Dehydrogenase; Mitochondria; NADP; Neurospora; Neurospora crassa; Phosphoric Monoester Hydrolases; Pyridoxal Phosphate; Pyruvates; Succinates; Thiamine Pyrophosphate; Valine | 1972 |
The cellular production of hydrogen peroxide.
Topics: Adenosine Diphosphate; Alanine; Animals; Antimycin A; Azides; Catalase; Cells; Cytochrome c Group; Cytosol; Hydrogen Peroxide; Kinetics; Liver; Mitochondria; Mitochondria, Liver; NADP; Organoids; Oxidation-Reduction; Peroxidases; Rats; Saccharomyces cerevisiae; Spectrophotometry; Subcellular Fractions; Succinates; Uric Acid | 1972 |
Bioluminescent assays of picomole levels of various metabolites using immobilized enzymes.
Topics: Alanine; Enzymes, Immobilized; FMN Reductase; Gluconates; Glucose; Glutamates; Lactates; Luciferases; Luminescent Measurements; Malates; Microchemistry; NAD; NADH, NADPH Oxidoreductases; NADP | 1982 |
D175 discriminates between NADH and NADPH in the coenzyme binding site of Lactobacillus delbrueckii subsp. bulgaricus D-lactate dehydrogenase.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Bacteria; Base Sequence; Binding Sites; Consensus Sequence; Kinetics; L-Lactate Dehydrogenase; Lactobacillus; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Oligodeoxyribonucleotides; Point Mutation; Recombinant Proteins; Sequence Homology, Amino Acid; Substrate Specificity | 1995 |
The choice of reducing substrate is altered by replacement of an alanine by a proline in the FAD domain of a bispecific NAD(P)H-nitrate reductase from birch.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Codon; Flavin-Adenine Dinucleotide; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Nitrate Reductase (NAD(P)H); Nitrate Reductases; Oxidation-Reduction; Proline; Recombinant Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Trees | 1995 |
Effects of substitution of Thr63 by alanine on the structure and function of Lactobacillus casei dihydrofolate reductase.
Topics: Alanine; Kinetics; Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; Methotrexate; Models, Molecular; Mutagenesis, Site-Directed; NADP; Solutions; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thermodynamics; Threonine | 1994 |
Reductive and oxidative half-reactions of glutathione reductase from Escherichia coli.
Topics: Alanine; Binding Sites; Escherichia coli; Glutathione Reductase; Histidine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction | 1994 |
Adding a positive charge at residue 46 of Drosophila alcohol dehydrogenase increases cofactor specificity for NADP+.
Topics: Alanine; Alcohol Dehydrogenase; Animals; Arginine; Codon; Drosophila; Electrochemistry; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; NADP; Protein Structure, Tertiary; Recombinant Proteins; Substrate Specificity | 1994 |
Is the NAD(P)H:flavin oxidoreductase from Escherichia coli a member of the ferredoxin-NADP+ reductase family?. Evidence for the catalytic role of serine 49 residue.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Catalysis; DNA Primers; Escherichia coli; Flavins; FMN Reductase; Hydroxyl Radical; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NADH, NADPH Oxidoreductases; NADP; Sequence Alignment; Serine; Threonine | 1996 |
The oxidative and reductive half reactions of subunit interface mutants of Escherichia coli glutathione reductase.
Topics: Alanine; Escherichia coli; Glutathione Reductase; Kinetics; Macromolecular Substances; NADP; Oxidation-Reduction; Point Mutation; Spectrophotometry; Valine | 1996 |
Modified ligands to FA and FB in photosystem I. Proposed chemical rescue of a [4Fe-4S] cluster with an external thiolate in alanine, glycine, and serine mutants of PsaC.
Topics: Alanine; Bacterial Proteins; Cytochromes; Cytochromes f; Electron Spin Resonance Spectroscopy; Electron Transport; Glycine; Iron-Sulfur Proteins; Kinetics; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Photosynthetic Reaction Center Complex Proteins; Photosystem I Protein Complex; Serine; Structure-Activity Relationship | 1996 |
Induction of p21 mediated by reactive oxygen species formed during the metabolism of aziridinylbenzoquinones by HCT116 cells.
Topics: Acetylcysteine; Alanine; Antineoplastic Agents; Aziridines; Benzoquinones; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dicumarol; Enzyme Inhibitors; Free Radicals; Humans; Hydrogen Peroxide; NADP; Oxidation-Reduction; Oxygen; Tumor Cells, Cultured | 1996 |
The nutritive function of glia is regulated by signals released by neurons.
Topics: Alanine; Ammonia; Animals; Bees; Glucose; Glutamic Acid; In Vitro Techniques; Male; Models, Biological; NAD; NADP; Neuroglia; Neurons; Photoreceptor Cells, Invertebrate; Proline; Retina; Signal Transduction | 1997 |
Effect of selective cysteine --> alanine replacements on the catalytic functions of lysine: N6-hydroxylase.
Topics: 2,6-Dichloroindophenol; Alanine; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cyanogen Bromide; Cysteine; Dithionitrobenzoic Acid; Flavoproteins; Iodoacetates; Iodoacetic Acid; Lysine; Mass Spectrometry; Mixed Function Oxygenases; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Peptide Fragments; Protein Conformation; Recombinant Proteins; Sequence Analysis; Trypsin | 1997 |
Modulation of striatal quinolinate neurotoxicity by elevation of endogenous brain kynurenic acid.
Topics: Alanine; Animals; Anticonvulsants; Corpus Striatum; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; GABA Antagonists; Huntington Disease; Injections, Intraventricular; Kynurenic Acid; Kynurenine; Male; NADP; Neurons, Afferent; Niacin; Probenecid; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
Rapid reduction of Hg(II) by mercuric ion reductase does not require the conserved C-terminal cysteine pair using HgBr2 as the substrate.
Topics: Alanine; Bacillus; Binding Sites; Bromides; Catalysis; Conserved Sequence; Cysteine; Glutathione Reductase; Kinetics; Mercury Compounds; Models, Molecular; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Oxidoreductases; Peptide Fragments; Substrate Specificity | 1998 |
Role of Arg100 and Arg264 from Anabaena PCC 7119 ferredoxin-NADP+ reductase for optimal NADP+ binding and electron transfer.
Topics: Alanine; Anabaena; Arginine; Circular Dichroism; Computer Simulation; Crystallography, X-Ray; Electron Transport; Escherichia coli; Ferredoxin-NADP Reductase; Glutamic Acid; Kinetics; Models, Molecular; NADP; Oxidation-Reduction; Recombinant Proteins; Spectrophotometry; Substrate Specificity | 1998 |
Structure of catalase-A from Saccharomyces cerevisiae.
Topics: Alanine; Binding Sites; Catalase; Crystallography, X-Ray; Heme; Models, Molecular; Mutagenesis, Site-Directed; NADP; Protein Conformation; Saccharomyces cerevisiae; Valine | 1999 |
Thioredoxin reductase from Plasmodium falciparum: evidence for interaction between the C-terminal cysteine residues and the active site disulfide-dithiol.
Topics: Alanine; Animals; Binding Sites; Cysteine; Disulfides; Dithionite; Dithionitrobenzoic Acid; Kinetics; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Peptide Fragments; Plasmodium falciparum; Thioredoxin-Disulfide Reductase; Titrimetry; Toluene | 1999 |
Role of the lateral channel in catalase HPII of Escherichia coli.
Topics: Alanine; Base Sequence; Binding Sites; Biopolymers; Catalase; DNA Primers; Enzyme Inhibitors; Escherichia coli; Mutagenesis, Site-Directed; NADP; Protein Conformation | 1999 |
The cysteine-proximal aspartates in the Fx-binding niche of photosystem I. Effect of alanine and lysine replacements on photoautotrophic growth, electron transfer rates, single-turnover flash efficiency, and EPR spectral properties.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Binding Sites; Cyanobacteria; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport; Kinetics; Lysine; Membrane Proteins; Mutagenesis, Site-Directed; NADP; Photosynthetic Reaction Center Complex Proteins; Photosystem I Protein Complex; Structure-Activity Relationship | 1999 |
Glutamate synthase: identification of the NADPH-binding site by site-directed mutagenesis.
Topics: Adenine Nucleotides; Alanine; Amino Acid Substitution; Azospirillum brasilense; Binding Sites; Catalysis; DNA, Bacterial; Flavin-Adenine Dinucleotide; Fluorescent Dyes; Glutamate Synthase; Glycine; Mutagenesis, Site-Directed; NADP; Operon; Recombinant Proteins; Sequence Analysis, DNA; Spectrophotometry; Titrimetry | 2000 |
Serine 121 is an essential amino acid for biotin sulfoxide reductase functionality.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Binding Sites; Biotin; Catalysis; Chromatography, High Pressure Liquid; Coenzymes; Conserved Sequence; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Factor Xa; Glutathione Transferase; Guanine Nucleotides; Iron-Sulfur Proteins; Ligands; Mass Spectrometry; Metalloproteins; Molecular Sequence Data; Molybdenum Cofactors; Mutagenesis, Site-Directed; NADP; Oxidative Stress; Oxidoreductases; Oxygen; Paraquat; Pteridines; Pterins; Recombinant Fusion Proteins; Rhodobacter sphaeroides; Sequence Homology, Amino Acid; Serine; Spectrometry, Fluorescence; Threonine; Time Factors | 2000 |
Trp-676 facilitates nicotinamide coenzyme exchange in the reductive half-reaction of human cytochrome P450 reductase: properties of the soluble W676H and W676A mutant reductases.
Topics: Alanine; Binding Sites; Catalysis; Cytochrome c Group; Enzyme Activation; Flavin-Adenine Dinucleotide; Histidine; Humans; Kinetics; Mutagenesis, Site-Directed; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Protein Structure, Tertiary; Recombinant Proteins; Solubility; Spectrometry, Fluorescence; Thermodynamics; Tryptophan | 2000 |
Coenzyme specificity of human monomeric carbonyl reductase: contribution of Lys-15, Ala-37 and Arg-38.
Topics: Alanine; Alcohol Oxidoreductases; Arginine; Binding Sites; Coenzymes; Escherichia coli; Humans; In Vitro Techniques; Kinetics; Lysine; Mutagenesis, Site-Directed; NAD; NADP; Recombinant Proteins | 2001 |
Optimizing an artificial metabolic pathway: engineering the cofactor specificity of Corynebacterium 2,5-diketo-D-gluconic acid reductase for use in vitamin C biosynthesis.
Topics: Alanine; Amino Acid Substitution; Ascorbic Acid; Binding Sites; Corynebacterium; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Gluconates; Glycine; Kinetics; Mutagenesis, Site-Directed; NAD; NADP; Phenylalanine; Recombinant Fusion Proteins; Sugar Alcohol Dehydrogenases; Thermodynamics; Tyrosine | 2002 |
Structural and thermodynamic studies on a salt-bridge triad in the NADP-binding domain of glutamate dehydrogenase from Thermotoga maritima: cooperativity and electrostatic contribution to stability.
Topics: Alanine; Arginine; Binding Sites; Crystallography, X-Ray; Cysteine; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Guanidine; Lysine; Mutagenesis, Site-Directed; NADP; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Salts; Serine; Static Electricity; Structure-Activity Relationship; Thermodynamics; Thermotoga maritima; Urea | 2002 |
Essential glycine in the proton channel of Escherichia coli transhydrogenase.
Topics: Alanine; Amino Acid Sequence; Catalysis; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glycine; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; NADP Transhydrogenases; Protein Conformation; Protein Structure, Tertiary; Protons; Serine | 2003 |
[STUDY OF THE PURIFICATION AND PROPERTIES OF 6-PHOSPHOGLUCONATE DEHYDROGENASE (6 PGD) EXTRACTED FROM BACILLUS SUBTILIS].
Topics: Alanine; Bacillus subtilis; Chromatography; Cysteine; Enzyme Inhibitors; Gluconates; Glycine; Glycosides; Ion Exchange Resins; NADP; Oxidoreductases; Peptides; Phosphogluconate Dehydrogenase; Prostaglandins D; Research; Sulfhydryl Compounds; Valine | 1963 |
PLASMA AMINO ACID PATTERNS IN ALCOHOLISM: THE EFFECTS OF ETHANOL LOADING.
Topics: Alanine; Alcoholism; Amino Acids; Autoanalysis; Biomedical Research; Blood; Ethanol; Genetics, Medical; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Methionine; NAD; NADP; Proline; Proteins; Serine; Toxicology; Valine | 1964 |
REAGENT-INDUCED CHANGES IN THE STRUCTURE AND CATALYTIC ACTIVITY OF GLUTAMIC DEHYDROGENASE.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Oxidoreductases; Antigen-Antibody Reactions; Catalysis; Copper; Diethylstilbestrol; Edetic Acid; Enzyme Inhibitors; Glutamate Dehydrogenase; Guanine Nucleotides; Immunoelectrophoresis; Manganese; NAD; NADP; Phenanthrolines; Research; Zinc | 1964 |
VARIATION IN ALANINE DEHYDROGENASE AND GLUTAMATE DEHYDROGENASE DURING THE SYNCHRONOUS DEVELOPMENT OF CHLAMYDOMONAS.
Topics: Alanine; Alanine Dehydrogenase; Amino Acid Oxidoreductases; Amino Acids; Ammonium Chloride; Ammonium Compounds; Autoradiography; Carbon Dioxide; Carbon Isotopes; Chlamydomonas; Chromatography; Eukaryota; Glutamate Dehydrogenase; Glutamates; Malate Dehydrogenase; Manometry; NADP; Photosynthesis; Plants; Pyruvates; Quaternary Ammonium Compounds; Research; Spectrophotometry | 1964 |
PURIFICATION AND PROPERTIES OF THE ALANINE RACEMASE FROM BACILLUS SUBTILIS.
Topics: Alanine; Alanine Racemase; Amino Acid Oxidoreductases; Animals; Bacillus subtilis; Cattle; D-Amino-Acid Oxidase; Dialysis; Edetic Acid; Electrophoresis; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Glutathione; Hot Temperature; Isomerases; Mercury; NAD; NADP; Oxidoreductases; Pharmacology; Pyridoxal Phosphate; Renal Dialysis; Research; Serum Albumin; Serum Albumin, Bovine; Streptomycin | 1964 |
HORMONAL REGULATION OF ENZYME ACTIVITY.
Topics: Adenine Nucleotides; Alanine; Amino Acid Oxidoreductases; Diethylstilbestrol; Enzyme Inhibitors; Estradiol; Estriol; Estrone; Glutamate Dehydrogenase; Guanine Nucleotides; Hormones; Hydroxyprogesterones; Mercury; Metabolism; Models, Theoretical; NAD; NADP; Phenanthrolines; Pregnenolone; Progesterone; Research | 1965 |
PHOSPHOENOLPYRUVATE CARBOXYLASE ACTIVITY AND GLYCOGENESIS IN THE FLATWORM, HYMENOLEPIS DIMINUTA.
Topics: Adenosine Triphosphate; Alanine; Alcohol Oxidoreductases; Animals; Aspartic Acid; Carbohydrate Metabolism; Carbon Dioxide; Carboxy-Lyases; Cestoda; Citric Acid Cycle; Dialysis; Fumarates; Glutamates; Glycogen; Glycolysis; Hymenolepis diminuta; Keto Acids; Lactates; Malates; NAD; NADP; Oxaloacetates; Phosphoenolpyruvate Carboxylase; Platyhelminths; Pyruvates; Renal Dialysis; Research; Succinates | 1965 |
SIMULTANEOUS INDUCTION AND REPRESSION OF NITRATE REDUCTASE AND TPNH CYTOCHROME REDUCTASE IN NEUROSPORA CRASSA.
Topics: Adenine; Alanine; Ammonia; Arginine; Aspartic Acid; Cytochrome Reductases; Cytochromes; Electron Transport; Enzyme Repression; Flavin-Adenine Dinucleotide; Hot Temperature; Kinetics; Lyases; Molecular Biology; Mutation; NADP; Neurospora; Neurospora crassa; Nitrate Reductase; Nitrate Reductases; Nitrates; Nitrites; Oxidoreductases; Pharmacology; Proteins; Research | 1965 |
Relaxing the nicotinamide cofactor specificity of phosphite dehydrogenase by rational design.
Topics: Alanine; Amino Acid Sequence; Chromatography, High Pressure Liquid; Computer Simulation; Enzyme Stability; Escherichia coli Proteins; Glutamic Acid; Hot Temperature; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NADH, NADPH Oxidoreductases; NADP; Niacinamide; Protein Engineering; Sequence Homology, Amino Acid; Substrate Specificity; Thermodynamics | 2003 |
An appraisal of multiple NADPH binding-site models proposed for cytochrome P450 reductase, NO synthase, and related diflavin reductase systems.
Topics: Alanine; Bacillus megaterium; Binding Sites; Catalysis; Cysteine; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; NADP; NADPH-Ferrihemoprotein Reductase; Nitric Oxide Synthase; Oxidation-Reduction; Spectrophotometry; Substrate Specificity | 2004 |
Alanine scanning mutagenesis of the testosterone binding site of rat 3 alpha-hydroxysteroid dehydrogenase demonstrates contact residues influence the rate-determining step.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); Alanine; Amino Acid Substitution; Animals; Binding Sites; Catalysis; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Progesterone; Protein Binding; Rats; Recombinant Proteins; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity; Testosterone | 2004 |
Switching pyridine nucleotide specificity in P450 BM3: mechanistic analysis of the W1046H and W1046A enzymes.
Topics: Alanine; Amino Acid Substitution; Animals; Bacillus megaterium; Bacterial Proteins; Cytochrome P-450 Enzyme System; Flavin-Adenine Dinucleotide; Histidine; Kinetics; Mixed Function Oxygenases; Mutation; NADP; NADPH-Ferrihemoprotein Reductase; Potentiometry; Protein Structure, Tertiary; Pyridines; Rats; Spectrophotometry; Substrate Specificity; Thermodynamics; Tryptophan | 2005 |
The structure of Apo R268A human aldose reductase: hinges and latches that control the kinetic mechanism.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); Alanine; Aldehyde Reductase; Arginine; Base Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; Glycine; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; NADP; Protein Conformation; Serine; Static Electricity; Stereoisomerism; Temperature; Ultraviolet Rays | 2005 |
The unexpected structural role of glutamate synthase [4Fe-4S](+1,+2) clusters as demonstrated by site-directed mutagenesis of conserved C residues at the N-terminus of the enzyme beta subunit.
Topics: Alanine; Amino Acid Sequence; Ammonia; Animals; Azospirillum brasilense; Cattle; Chromatography; Dihydrouracil Dehydrogenase (NADP); Dose-Response Relationship, Drug; Electron Transport; Electrons; Electrophoresis, Polyacrylamide Gel; Flavins; Glutamate Synthase; Glutarates; Imino Acids; Iron; Iron-Sulfur Proteins; Ketoglutaric Acids; Kinetics; Models, Biological; Models, Genetic; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; NADP; Oligonucleotides; Plasmids; Promoter Regions, Genetic; Protein Conformation; Protein Engineering; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrophotometry | 2005 |
Disulfiram irreversibly aggregates betaine aldehyde dehydrogenase--a potential target for antimicrobial agents against Pseudomonas aeruginosa.
Topics: Alanine; Anti-Infective Agents; Betaine-Aldehyde Dehydrogenase; Binding Sites; Catalysis; Chromatography; Cysteine; Disulfiram; Dithionitrobenzoic Acid; Enzyme Inhibitors; Glutathione; Kinetics; Methyl Methanesulfonate; Models, Chemical; Mutagenesis, Site-Directed; Mutation; NADP; Protein Conformation; Protein Structure, Quaternary; Proteins; Pseudomonas aeruginosa; Sulfhydryl Compounds; Temperature; Time Factors | 2006 |
The role of a conserved serine residue within hydrogen bonding distance of FAD in redox properties and the modulation of catalysis by Ca2+/calmodulin of constitutive nitric-oxide synthases.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Calcium; Calmodulin; Catalysis; Electron Transport; Flavin-Adenine Dinucleotide; Humans; Hydrogen Bonding; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Oxidation-Reduction; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Serine; Threonine | 2006 |
Saturation transfer difference NMR studies on substrates and inhibitors of succinic semialdehyde dehydrogenases.
Topics: Alanine; Aldehydes; Animals; Binding Sites; Cloning, Molecular; Cysteine; Drosophila Proteins; Enzyme Inhibitors; Escherichia coli Proteins; gamma-Aminobutyric Acid; Hydrocarbons, Aromatic; NAD; NADP; Nuclear Magnetic Resonance, Biomolecular; Substrate Specificity; Succinate-Semialdehyde Dehydrogenase | 2008 |
Cysteine as a modulator residue in the active site of xenobiotic reductase A: a structural, thermodynamic and kinetic study.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Coumarins; Cysteine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Protein Conformation; Pseudomonas putida; Serine; Substrate Specificity; Thermodynamics; Xenobiotics | 2010 |
The effect of active-site isoleucine to alanine mutation on the DHFR catalyzed hydride-transfer.
Topics: Alanine; Amino Acid Substitution; Catalysis; Catalytic Domain; Escherichia coli; Isoleucine; Kinetics; Molecular Dynamics Simulation; Mutation; NADP; Tetrahydrofolate Dehydrogenase | 2010 |
Stereoselective degradation of metalaxyl and its enantiomers in rat and rabbit hepatic microsomes in vitro.
Topics: Alanine; Animals; Chromatography, High Pressure Liquid; Fungicides, Industrial; Kinetics; Male; Microsomes, Liver; NADP; Rabbits; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Stereoisomerism; Structure-Activity Relationship | 2012 |
Metabolic chiral inversion of brivanib and its relevance to safety and pharmacology.
Topics: Administration, Oral; Adolescent; Adult; Alanine; Animals; Area Under Curve; Cytosol; Female; Humans; Ketones; Macaca fascicularis; Male; Microsomes, Liver; Middle Aged; NADP; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Receptor, Fibroblast Growth Factor, Type 1; Triazines; Vascular Endothelial Growth Factor Receptor-2; Young Adult | 2012 |
Arg279 is the key regulator of coenzyme selectivity in the flavin-dependent ornithine monooxygenase SidA.
Topics: Alanine; Arginine; Aspergillus fumigatus; Escherichia coli; Flavins; Fungal Proteins; Glutamic Acid; Hydroxylation; Kinetics; Mixed Function Oxygenases; Models, Molecular; Mutagenesis, Site-Directed; NAD; NADP; Ornithine; Oxidation-Reduction; Oxygen; Protein Conformation; Recombinant Fusion Proteins; Static Electricity; Substrate Specificity | 2014 |
Determinants of Cofactor Specificity for the Glucose-6-Phosphate Dehydrogenase from Escherichia coli: Simulation, Kinetics and Evolutionary Studies.
Topics: Alanine; Amino Acid Motifs; Bayes Theorem; Binding Sites; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Evolution, Molecular; Glucosephosphate Dehydrogenase; Kinetics; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Mutation; NADP; Phylogeny; Plasmids; Substrate Specificity | 2016 |
Role of active site loop in coenzyme binding and flavin reduction in cytochrome P450 reductase.
Topics: Alanine; Arabidopsis; Arginine; Aspartic Acid; Bacillus megaterium; Catalysis; Catalytic Domain; Chromatography, High Pressure Liquid; Cytochromes c; Flavins; Humans; Hydrogen Bonding; Kinetics; Mutagenesis, Site-Directed; Mutation; NADP; NADPH-Ferrihemoprotein Reductase; Protein Binding; Protein Domains; Saccharomyces cerevisiae; Static Electricity; Tryptophan | 2016 |
Understanding the high L-valine production in Corynebacterium glutamicum VWB-1 using transcriptomics and proteomics.
Topics: Alanine; Corynebacterium glutamicum; Leucine; NADP; Proteomics; Pyruvic Acid; Transcriptome; Valine | 2018 |