Compounds > alanine

alanine and n-methylscopolamine

alanine has been researched along with n-methylscopolamine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (71.43)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Birdsall, NJ; Lazareno, S; Matsui, H1
Lameh, J; Moro, O; Sadée, W; Shockley, MS1
Cheng, E; Cline, RT; Fraser, CM; Geoghagen, NS; Lee, NH1
Schöneberg, T; Soldner, A; Wess, J; Zeng, FY1
Curtis, CA; Hulme, EC; Ward, SD1
Bloodworth, LM; Hamdan, FF; Siddiqui, NA; Ward, SD; Wess, J1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1

Other Studies

7 other study(ies) available for alanine and n-methylscopolamine

ArticleYear
Probing of the location of the allosteric site on m1 muscarinic receptors by site-directed mutagenesis.
    Molecular pharmacology, 1995, Volume: 47, Issue:1

    Topics: Acetylcholine; Alanine; Allosteric Regulation; Animals; Base Sequence; Binding Sites; Binding, Competitive; Gallamine Triethiodide; Kinetics; Molecular Sequence Data; Muscarinic Antagonists; Mutagenesis, Site-Directed; Mutation; N-Methylscopolamine; Receptors, Muscarinic; Scopolamine Derivatives; Tritium; Tryptophan

1995
Overlapping multi-site domains of the muscarinic cholinergic Hm1 receptor involved in signal transduction and sequestration.
    The Journal of biological chemistry, 1994, Mar-04, Volume: 269, Issue:9

    Topics: Alanine; Amino Acid Sequence; Cell Line; Conserved Sequence; Genetic Vectors; Humans; Kidney; Kinetics; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylscopolamine; Phosphatidylinositols; Point Mutation; Propanolamines; Protein Structure, Secondary; Quinuclidinyl Benzilate; Receptor, Muscarinic M1; Receptors, Muscarinic; Scopolamine Derivatives; Signal Transduction

1994
Alanine scanning mutagenesis of conserved arginine/lysine-arginine/lysine-X-X-arginine/lysine G protein-activating motifs on m1 muscarinic acetylcholine receptors.
    Molecular pharmacology, 1996, Volume: 50, Issue:1

    Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Binding, Competitive; Carbachol; Cell Membrane; CHO Cells; Conserved Sequence; Cricetinae; DNA Primers; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylscopolamine; Oxotremorine; Protein Structure, Secondary; Quinuclidinyl Benzilate; Receptor, Muscarinic M2; Receptors, Muscarinic; Recombinant Proteins; Scopolamine Derivatives; Second Messenger Systems; Transfection

1996
Conserved extracellular cysteine pair in the M3 muscarinic acetylcholine receptor is essential for proper receptor cell surface localization but not for G protein coupling.
    Journal of neurochemistry, 1999, Volume: 72, Issue:6

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Carbachol; Cell Membrane; Conserved Sequence; COS Cells; Cysteine; Disulfides; GTP-Binding Proteins; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylscopolamine; Phosphatidylinositols; Protein Structure, Secondary; Radioligand Assay; Rats; Receptor, Muscarinic M3; Receptors, Muscarinic; Recombinant Proteins; Transfection; Tritium

1999
Alanine-scanning mutagenesis of transmembrane domain 6 of the M(1) muscarinic acetylcholine receptor suggests that Tyr381 plays key roles in receptor function.
    Molecular pharmacology, 1999, Volume: 56, Issue:5

    Topics: Acetylcholine; Alanine; Animals; Atropine; Binding, Competitive; COS Cells; Immunohistochemistry; Ligands; Muscarinic Agonists; Muscarinic Antagonists; Mutagenesis, Site-Directed; N-Methylscopolamine; Oxotremorine; Phosphatidylinositols; Pilocarpine; Protein Structure, Tertiary; Quinuclidinyl Benzilate; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Tyrosine

1999
Use of an in situ disulfide cross-linking strategy to map proximities between amino acid residues in transmembrane domains I and VII of the M3 muscarinic acetylcholine receptor.
    Biochemistry, 2002, Jun-18, Volume: 41, Issue:24

    Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; COS Cells; Cross-Linking Reagents; Cysteine; Disulfides; Ethyl Methanesulfonate; Hydrolysis; Ligands; Molecular Sequence Data; Muscarinic Agonists; Muscarinic Antagonists; Mutagenesis, Site-Directed; N-Methylscopolamine; Peptide Fragments; Peptide Mapping; Phosphatidylinositols; Protein Structure, Tertiary; Rats; Receptor, Muscarinic M3; Receptors, Muscarinic; Sulfhydryl Compounds; Transfection; Tritium

2002
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009