alanine and n-benzoylalanine

alanine has been researched along with n-benzoylalanine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.45)18.7374
1990's15 (48.39)18.2507
2000's10 (32.26)29.6817
2010's3 (9.68)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Guiochon, G; Jacobson, SC1
Hisaoka, M; Kamoshida, K; Kurihara, A; Mikuni, N1
Inoue, Y; Kuhara, T; Matsumoto, I; Matsumoto, M; Shinka, T1
Hirouchi, Y; Hori, R; Inui, K; Kamiya, A; Kawahara, Y; Naganuma, H; Okada, R2
Kawahara, Y; Shimada, J1
Hasegawa, T; Nabeshima, T; Nadai, M; Wang, L1
Allenmark, SG; Andersson, S; Guiochon, G; Jacobson, SC1
Irimajiri, S; Masuda, T; Matsuoka, Y; Obana, M; Suzuki, A1
Arimori, K; Kitagawa, A; Kobayashi, M; Nakamura, C; Nakano, M; Tokunaga, J5
Haruta, T; Hata, I; Mayumi, M; Tsukahara, H1
Kim, SH; Kim, WB; Kwon, JW; Lee, MG1
Cihlar, T; Ho, ES; Lin, DC; Mendel, DB1
Aihara, Y; Fukamachi, K; Hori, T; Imamura, T; Kasuya, H; Kawashima, A; Kikuchi, K; Ochiai, T; Shiseki, M; Tozuka, K; Yamaguchi, K1
Kim, KH2
Cha, SH; Endou, H; Hosoyamada, M; Narikawa, S; Sekine, T; Takeda, M1
Gawandi, VB; Lima, S; Liskey, D; Phillips, RS1
Hishida, A; Kanamaru, M; Nagashima, S; Ohashi, N; Tajima, N; Togawa, A; Uematsu, T1
Abe, K; Arai, T; Hasebe, N; Horiuchi, M; Kimura, M; Tokumura, M1
Ishizuka, H; Naganuma, H; Tajima, N1
Connon, SJ; Gun'ko, YK; Peschiulli, A; Quigley, C; Tallon, S1
Do, H; Hong, S; Jung, Y; Kim, H; Kim, YM; Kong, H; Lee, Y; Yoon, JH1
Hitomi, S; Ishikawa, H; Maeno, T; Nakamura, H; Shichi, D; Suzuki, H; Tokuda, Y1
Kishida, H; Kogita, Y; Morii, K; Okushin, H; Takata, M; Uesaka, K; Yamamoto, T1
Li, J; Li, Y; Qin, Z; Song, S; Zhu, M1
Akamatsu, M; Asao, M; Fujita, T; Iwamura, H1

Trials

1 trial(s) available for alanine and n-benzoylalanine

ArticleYear
Overview of a new carbapenem, panipenem/betamipron.
    Drugs under experimental and clinical research, 1994, Volume: 20, Issue:6

    Topics: Alanine; Animals; Carbapenems; Dogs; Half-Life; Humans; In Vitro Techniques; Kidney; Macaca fascicularis; Rats; Rats, Wistar; Species Specificity; Thienamycins

1994

Other Studies

30 other study(ies) available for alanine and n-benzoylalanine

ArticleYear
Contribution of ionically immobilized bovine serum albumin to the retention of enantiomers.
    Journal of chromatography, 1992, May-27, Volume: 600, Issue:1

    Topics: Alanine; Animals; Cattle; Chromatography, Ion Exchange; Mandelic Acids; Serum Albumin, Bovine; Stereoisomerism

1992
Neurotoxicity of panipenem/betamipron, a new carbapenem, in rabbits: correlation to concentration in central nervous system.
    Journal of pharmacobio-dynamics, 1992, Volume: 15, Issue:7

    Topics: Alanine; Animals; beta-Alanine; Brain; Drug Therapy, Combination; Electroencephalography; Male; Rabbits; Thienamycins

1992
Benzoylalanine: detection and identification of an alanine conjugate with benzoic acid in hyperammonemic patients treated with sodium benzoate.
    Clinica chimica acta; international journal of clinical chemistry, 1985, Oct-15, Volume: 151, Issue:3

    Topics: Alanine; Ammonia; Benzoates; Benzoic Acid; Carboxylic Acids; Child, Preschool; Chromatography, Gas; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant; Infant, Newborn; Metabolism, Inborn Errors

1985
Protective effect of N-acyl amino acids (NAAs) on cephaloridine (CER) nephrotoxicity in rabbits.
    Japanese journal of pharmacology, 1993, Volume: 63, Issue:4

    Topics: Alanine; Amino Acids; Animals; Cephaloridine; Histocytochemistry; Injections, Intravenous; Kidney Tubules, Proximal; Male; Necrosis; Rabbits; Staining and Labeling

1993
Preventive effect of betamipron on nephrotoxicity and uptake of carbapenems in rabbit renal cortex.
    Japanese journal of pharmacology, 1994, Volume: 66, Issue:1

    Topics: Alanine; Animals; Carbapenems; Glycosuria, Renal; Imipenem; In Vitro Techniques; Kidney Cortex; Kidney Diseases; Male; Necrosis; Proteinuria; Rabbits; Thienamycins

1994
The effects of N-benzoyl-beta-alanine, a new nephroprotective drug, on the distribution and renal excretion of enprofylline in rats.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:7

    Topics: Alanine; Animals; Bronchodilator Agents; Injections, Intravenous; Kidney Tubules; Male; Protein Binding; Rats; Rats, Wistar; Xanthines

1993
Estimation of the number of enantioselective sites of bovine serum albumin using frontal chromatography.
    Chirality, 1993, Volume: 5, Issue:7

    Topics: Adsorption; Alanine; Binding Sites; Chromatography, Affinity; Mandelic Acids; Phenylbutyrates; Serum Albumin, Bovine; Stereoisomerism; Structure-Activity Relationship; Tryptophan

1993
[A case of infective endocarditis with purpura and macroscopic hematuria as initial manifestations].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1996, Volume: 70, Issue:4

    Topics: Acute Kidney Injury; Adult; Alanine; Endocarditis, Bacterial; Female; Hematuria; Humans; IgA Vasculitis; Thienamycins

1996
Protective effect of N-benzoyl-beta-alanine against cisplatin nephrotoxicity in rats.
    Renal failure, 1996, Volume: 18, Issue:2

    Topics: Alanine; Animals; Antineoplastic Agents; Body Weight; Cisplatin; Drug Evaluation, Preclinical; Kidney; Liver; Male; Organ Size; Random Allocation; Rats; Rats, Wistar; Time Factors

1996
Protective effects of N-benzoyl amino acids on cisplatin nephrotoxicity in rats.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:11

    Topics: Alanine; Animals; Antineoplastic Agents; Blood Urea Nitrogen; Body Weight; Cisplatin; Creatinine; Kidney; Liver; Male; Organ Size; Piperacillin; Rats; Rats, Wistar

1996
Effects of betamipron on cisplatin nephrotoxicity and its pharmacokinetics in rats.
    Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:4

    Topics: Alanine; Animals; Antineoplastic Agents; Bile; Blood Urea Nitrogen; Body Weight; Carcinoma 256, Walker; Cisplatin; Creatinine; Drug Antagonism; Intestines; Kidney; Male; Organ Size; Rats; Rats, Wistar

1997
Betamipron reduces cisplatin nephrotoxicity in rodents without modifying its antileukemic activity in mice.
    Renal failure, 1997, Volume: 19, Issue:3

    Topics: Acetylglucosaminidase; Alanine; Animals; Antineoplastic Agents; beta 2-Microglobulin; Blood Urea Nitrogen; Body Weight; Cisplatin; Creatinine; gamma-Glutamyltransferase; Kidney; Kidney Glomerulus; Kidney Tubules; Leukemia P388; Male; Mice; Rats; Rats, Wistar

1997
Protective effects of betamipron on renal toxicity during repeated cisplatin administration in rats and protective mechanism.
    Renal failure, 1998, Volume: 20, Issue:1

    Topics: Alanine; Animals; Antineoplastic Agents; Catalase; Cisplatin; Glutathione; Kidney; Kidney Cortex; Lipid Peroxides; Male; Rats; Rats, Wistar

1998
Nitric oxide in septic and aseptic meningitis in children.
    Scandinavian journal of clinical and laboratory investigation, 1998, Volume: 58, Issue:1

    Topics: Alanine; Anti-Bacterial Agents; Child; Child, Preschool; Dexamethasone; Female; Humans; Infant; Male; Meningitis, Aseptic; Meningitis, Haemophilus; Meningitis, Pneumococcal; Nitric Oxide; Thienamycins

1998
Nephroprotective effect of betamipron on a new carbapenem, DA-1131, in rabbits.
    Biopharmaceutics & drug disposition, 1999, Volume: 20, Issue:3

    Topics: Alanine; Animals; Carbapenems; Drug Interactions; Kidney Function Tests; Kidney Tubular Necrosis, Acute; Male; Protective Agents; Rabbits

1999
Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1.
    Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:3

    Topics: Adenine; Alanine; Animals; Anion Transport Proteins; Antiviral Agents; Biological Transport; Carrier Proteins; CHO Cells; Cidofovir; Cricetinae; Cytosine; Humans; Kidney; Organophosphate Poisoning; Organophosphonates; Organophosphorus Compounds; Probenecid

2000
[Two cases of methicillin-resistant Staphylococcus aureus (MRSA) sepsis following craniotomy].
    No shinkei geka. Neurological surgery, 2000, Volume: 28, Issue:5

    Topics: Adult; Aged; Alanine; Aminoglycosides; Ampicillin; Anti-Bacterial Agents; Craniotomy; Dibekacin; Drug Therapy, Combination; Female; Humans; Male; Meningeal Neoplasms; Meningioma; Methicillin Resistance; Postoperative Complications; Sepsis; Staphylococcal Infections; Sulbactam; Thienamycins; Treatment Outcome; Vancomycin

2000
Thermodynamic aspects of hydrophobicity and biological QSAR.
    Journal of computer-aided molecular design, 2001, Volume: 15, Issue:4

    Topics: Alanine; Binding Sites; Computer Simulation; Computer-Aided Design; Drug Design; Ligands; Models, Molecular; Proteins; Quantitative Structure-Activity Relationship; Receptors, Drug; Solvents; Thermodynamics; Water

2001
Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters.
    European journal of pharmacology, 2001, May-11, Volume: 419, Issue:2-3

    Topics: Alanine; Anion Transport Proteins; Carrier Proteins; Cells, Cultured; Cilastatin; Humans; Kidney Tubules, Proximal; Probenecid; Protease Inhibitors; Uricosuric Agents

2001
Thermodynamic quantitative structure-activity relationship analysis for enzyme-ligand interactions in aqueous phosphate buffer and organic solvent.
    Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:8

    Topics: Alanine; Chymotrypsin; Esters; Pentanols; Phosphates; Quantitative Structure-Activity Relationship; Solvents; Thermodynamics

2001
Reaction of Pseudomonas fluorescens kynureninase with beta-benzoyl-L-alanine: detection of a new reaction intermediate and a change in rate-determining step.
    Biochemistry, 2004, Mar-23, Volume: 43, Issue:11

    Topics: Alanine; Bacterial Proteins; Benzoates; Hydrolases; Kinetics; Kynurenine; Protons; Pseudomonas fluorescens; Pyruvic Acid; Recombinant Proteins; Spectrophotometry; Substrate Specificity

2004
Pharmacokinetics of panipenem/betamipron in patients with end-stage renal disease.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2005, Volume: 11, Issue:1

    Topics: Adult; Aged; Alanine; Anti-Bacterial Agents; Area Under Curve; Dose-Response Relationship, Drug; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Infusions, Intravenous; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Thienamycins

2005
Absence of convulsive liability of doripenem, a new carbapenem antibiotic, in comparison with beta-lactam antibiotics.
    Toxicology, 2006, May-01, Volume: 222, Issue:1-2

    Topics: Alanine; Animals; Anti-Bacterial Agents; Anticonvulsants; Carbapenems; Convulsants; Dogs; Doripenem; Drug Interactions; Electroencephalography; Injections, Intravenous; Injections, Intraventricular; Male; Meropenem; Mice; Mice, Inbred ICR; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Thienamycins; Valproic Acid

2006
Population pharmacokinetic analysis of panipenem/betamipron in patients with various degrees of renal function.
    Chemotherapy, 2006, Volume: 52, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Area Under Curve; Chromatography, High Pressure Liquid; Creatinine; Haemophilus influenzae; Humans; Kidney Function Tests; Metabolic Clearance Rate; Middle Aged; Renal Insufficiency; Thienamycins

2006
Organocatalytic asymmetric addition of alcohols and thiols to activated electrophiles: efficient dynamic kinetic resolution and desymmetrization protocols.
    The Journal of organic chemistry, 2008, Aug-15, Volume: 73, Issue:16

    Topics: Alanine; Alcohols; Amino Acids; Anhydrides; Cinchona Alkaloids; Kinetics; Lactones; Propanols; Sulfhydryl Compounds; Urea; Valine

2008
Structural effects of N-aromatic acyl-amino acid conjugates on their deconjugation in the cecal contents of rats: implication in design of a colon-specific prodrug with controlled conversion rate at the target site.
    Biopharmaceutics & drug disposition, 2011, Volume: 32, Issue:6

    Topics: Alanine; Amino Acids, Aromatic; Animals; Antimetabolites, Antineoplastic; Cecum; Colon; Delayed-Action Preparations; Fluorouracil; Gastrointestinal Contents; Hydrogen-Ion Concentration; Male; Molecular Targeted Therapy; Prodrugs; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

2011
A retrospective cohort study of panipenem/betamipron for adult pneumococcal bacteremia at three teaching hospitals in Japan.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2013, Volume: 19, Issue:4

    Topics: Aged; Aged, 80 and over; Alanine; Anti-Bacterial Agents; Bacteremia; Female; Hospitals, Teaching; Humans; Japan; Logistic Models; Male; Middle Aged; Pneumococcal Infections; Retrospective Studies; Streptococcus pneumoniae; Thienamycins; Treatment Outcome

2013
Reversible splenial lesion of the corpus callosum associated with bacterial meningitis.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2014, Volume: 19

    Topics: Alanine; Cerebrospinal Fluid; Corpus Callosum; Dexamethasone; Drainage; Humans; Liver Abscess; Magnetic Resonance Imaging; Male; Meningitis, Pneumococcal; Middle Aged; Streptococcus pneumoniae; Thienamycins; Tomography, X-Ray Computed; Treatment Outcome

2014
A Multiwell-Based Assay for Screening Thyroid Hormone Signaling Disruptors Using
    Molecules (Basel, Switzerland), 2022, Jan-25, Volume: 27, Issue:3

    Topics: Alanine; Animals; Endocrine Disruptors; Gene Expression; Halogenated Diphenyl Ethers; High-Throughput Screening Assays; Signal Transduction; Thyroid Hormones; Triiodothyronine; Xenopus laevis

2022
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:10

    Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste

1987