alanine and morphine

alanine has been researched along with morphine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19909 (40.91)18.7374
1990's3 (13.64)18.2507
2000's7 (31.82)29.6817
2010's2 (9.09)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Ho, IK; Loh, HH; Way, EL1
Larson, AA1
Davis, JO; Spielman, WS1
Bachelard, HS; Lindsay, JR1
Contreras, E; Tamayo, L1
Hepler, JR; Myers, RD; Noto, T1
Calverley, PM; Carmichael, GL; Scott, DB1
Holm, AC; Ogren, SO1
Brodin, E; Franck, J; Rosén, A1
Coderre, TJ; Fundytus, ME1
Reilly, S; Trifunovic, R1
Fournié-Zaluski, M; Hutcheson, DM; Maldonado, R; Pache, DM; Roques, BP; Sewell, RD; Subhan, F1
Chaipatikul, V; Law, PY; Loh, HH1
CONTRERAS, E; CROXATTO, R; HUIDOBRO, F1
Brillet, K; Kieffer, BL; Massotte, D1
Celver, J; Chavkin, C; Jin, W; Lowe, J; Xu, M1
Bezancon, E; Franconi, JM; Merle, M; Serres, S1
Jafari, MT1
Becker, A; Doll, C; Glück, L; Grecksch, G; Höllt, V; Imhof, AK; Just, S; Koch, T; Lupp, A; Pierstorff, C; Schulz, S; Stumm, R1
Fakira, AK; Lee, HT; Liu, J; Melyan, Z; Morón, JA; Neve, R; Portugal, GS; Russo, SJ; Xia, Y1
Atwal, H; Ayoub, SM; Collins, SA; Di Marzo, V; Farag, M; Iannotti, FA; Leri, F; Lichtman, AH; Limebeer, CL; Mechoulam, R; Parker, LA; Piscitelli, F; Rock, EM; Smoum, R1
Duffy, EM; Jorgensen, WL1

Trials

1 trial(s) available for alanine and morphine

ArticleYear
Effects of alaproclate and morphine on the ventilatory response to carbon dioxide in normal man.
    British journal of anaesthesia, 1983, Volume: 55, Issue:9

    Topics: Adult; Alanine; Carbon Dioxide; Depression, Chemical; Drug Synergism; Humans; Male; Morphine; Respiration; Time Factors

1983

Other Studies

21 other study(ies) available for alanine and morphine

ArticleYear
Pharmacological manipulation of gamma-aminobutyric acid (GABA) in morphine analgesia, tolerance and physical dependence.
    Life sciences, 1976, May-15, Volume: 18, Issue:10

    Topics: Alanine; Aminobutyrates; Aminooxyacetic Acid; Analgesia; Animals; Bicuculline; Biological Transport; Drug Interactions; Drug Tolerance; gamma-Aminobutyric Acid; Humans; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Receptors, Drug; Substance Withdrawal Syndrome; Substance-Related Disorders

1976
Intrathecal GABA, glycine, taurine or beta-alanine elicits dyskinetic movements in mice.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:2

    Topics: Alanine; Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glycine; Injections, Intraperitoneal; Injections, Spinal; Male; Mice; Morphine; Movement Disorders; Naloxone; Strychnine; Taurine; Time Factors

1989
The renin-angiotensin system and aldosterone secretion during sodium depletion in the rat.
    Circulation research, 1974, Volume: 35, Issue:4

    Topics: Adrenocorticotropic Hormone; Alanine; Aldosterone; Angiotensin II; Animals; Blood Pressure; Corticosterone; Dexamethasone; Drug Synergism; Enzyme Inhibitors; Hypophysectomy; Kidney; Male; Morphine; Nephrectomy; Oligopeptides; Pituitary Gland, Anterior; Rats; Renin; Sarcosine; Sodium

1974
Effects of neurotropic drugs on glucose metabolism in rat brain in vivo.
    Biochemical pharmacology, 1966, Volume: 15, Issue:8

    Topics: Alanine; Amino Acids; Aminobutyrates; Amphetamine; Animals; Aspartic Acid; Brain; Carbon Isotopes; Chlorpromazine; Glucose; Glutamates; Glutamine; Glutarates; Iproniazid; Keto Acids; Male; Morphine; Pentobarbital; Pyruvates; Rats

1966
Effects of glycine, beta-alanine and diazepam upon morphine-tolerant-dependent mice.
    The Journal of pharmacy and pharmacology, 1980, Volume: 32, Issue:5

    Topics: Alanine; Analgesia; Animals; beta-Alanine; Diazepam; Drug Interactions; Drug Tolerance; Female; Glycine; Humans; Mice; Morphine; Morphine Dependence; Naloxone; Substance Withdrawal Syndrome

1980
Profile of amino acid synthesis in rat hippocampus during push-pull perfusion of ethanol or morphine.
    Neuroscience, 1984, Volume: 13, Issue:2

    Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Ethanol; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Hippocampus; Male; Morphine; Rats; Rats, Inbred Strains

1984
Test-specific effects of the 5-HT reuptake inhibitors alaproclate and zimelidine on pain sensitivity and morphine analgesia.
    Journal of neural transmission, 1980, Volume: 47, Issue:4

    Topics: Alanine; Analgesia; Animals; Behavior, Animal; Brompheniramine; Desipramine; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; p-Chloroamphetamine; Pain; Pyridines; Rats; Serotonin; Zimeldine

1980
Effects of acute systemic treatment with the 5 HT-uptake blocker alaproclate on tissue levels and release of substance P in rat periaqueductal grey.
    Neuropeptides, 1995, Volume: 28, Issue:6

    Topics: 5,7-Dihydroxytryptamine; Alanine; Animals; Cholecystokinin; Kinetics; Male; Morphine; Neurokinin A; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Substance P

1995
Effect of activity at metabotropic, as well as ionotropic (NMDA), glutamate receptors on morphine dependence.
    British journal of pharmacology, 1994, Volume: 113, Issue:4

    Topics: Alanine; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzoates; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Injections, Intraventricular; Injections, Subcutaneous; Male; Morphine; Morphine Dependence; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome

1994
Progressive ratio performance in rats with gustatory thalamus lesions.
    Behavioral neuroscience, 1999, Volume: 113, Issue:5

    Topics: Alanine; Animals; Drinking Behavior; Electric Stimulation; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reaction Time; Reinforcement Schedule; Reward; Taste; Thalamic Nuclei

1999
Analgesic doses of the enkephalin degrading enzyme inhibitor RB 120 do not have discriminative stimulus properties.
    European journal of pharmacology, 2000, Aug-04, Volume: 401, Issue:2

    Topics: Alanine; Analgesics; Animals; Anti-Anxiety Agents; Discrimination Learning; Discrimination, Psychological; Disulfides; Dose-Response Relationship, Drug; Indoles; Male; Meglumine; Morphine; Protease Inhibitors; Rats; Rats, Wistar

2000
Ligand-selective activation of mu-oid receptor: demonstrated with deletion and single amino acid mutations of third intracellular loop domain.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:3

    Topics: Adenylyl Cyclases; Alanine; Analgesics, Opioid; Cells, Cultured; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gene Deletion; Humans; Membrane Proteins; Morphine; Narcotic Antagonists; Pertussis Toxin; Protein Structure, Tertiary; Receptors, Opioid, mu

2003
STUDIES ON MORPHINE. IV. EFFECTS OF SOME METABOLITES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
    Archives internationales de pharmacodynamie et de therapie, 1963, Dec-01, Volume: 146

    Topics: Alanine; Cyanides; Fluoroacetates; Glutamine; Iodoacetates; Mice; Morphine; NAD; Nalorphine; Niacin; Niacinamide; Pharmacology; Pyridines; Pyridoxine; Research; Serine; Toxicology; Tryptophan

1963
Enhanced spontaneous activity of the mu opioid receptor by cysteine mutations: characterization of a tool for inverse agonist screening.
    BMC pharmacology, 2003, Dec-01, Volume: 3

    Topics: Alanine; Cells, Cultured; Cysteine; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Morphine; Mutation; Narcotic Antagonists; Receptors, Opioid, mu; Sulfur Radioisotopes

2003
Distinct domains of the mu-opioid receptor control uncoupling and internalization.
    Molecular pharmacology, 2004, Volume: 65, Issue:3

    Topics: Alanine; Amino Acid Substitution; Animals; Arrestin; Cells, Cultured; G Protein-Coupled Inwardly-Rectifying Potassium Channels; G-Protein-Coupled Receptor Kinase 3; Green Fluorescent Proteins; Humans; Luminescent Proteins; Morphine; Oocytes; Phagocytosis; Phosphorylation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Receptors, Opioid, mu; Threonine; Xenopus laevis

2004
Ex vivo analysis of lactate and glucose metabolism in the rat brain under different states of depressed activity.
    The Journal of biological chemistry, 2004, Nov-12, Volume: 279, Issue:46

    Topics: Alanine; Analgesics, Opioid; Animals; Brain; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulation; Chloralose; Female; Glucose; Hypnotics and Sedatives; Lactic Acid; Morphine; Nuclear Magnetic Resonance, Biomolecular; Pentobarbital; Rats; Rats, Wistar; Tissue Extracts

2004
Improved design for high resolution electrospray ionization ion mobility spectrometry.
    Talanta, 2009, Mar-15, Volume: 77, Issue:5

    Topics: Alanine; Butylamines; Codeine; Equipment Design; Morphine; Organothiophosphorus Compounds; Spectrometry, Mass, Electrospray Ionization

2009
Analgesic tolerance to high-efficacy agonists but not to morphine is diminished in phosphorylation-deficient S375A μ-opioid receptor knock-in mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Sep-28, Volume: 31, Issue:39

    Topics: Alanine; Analgesics, Opioid; Animals; Drug Tolerance; Gene Knock-In Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Morphine; Pain Measurement; Phosphorylation; Receptors, Opioid, mu; Serine

2011
Hippocampal GluA1-containing AMPA receptors mediate context-dependent sensitization to morphine.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Nov-09, Volume: 31, Issue:45

    Topics: Alanine; Analysis of Variance; Animals; Behavior, Animal; Carrier Proteins; Cell Cycle Proteins; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Gene Transfer Techniques; Green Fluorescent Proteins; Guanylate Kinases; Hippocampus; In Situ Nick-End Labeling; Long-Term Potentiation; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Motor Activity; Mutation; Narcotics; Nuclear Proteins; Phosphorylation; Protein Transport; Random Allocation; Receptors, AMPA; Serine; Subcellular Fractions

2011
Oleoyl alanine (HU595): a stable monomethylated oleoyl glycine interferes with acute naloxone precipitated morphine withdrawal in male rats.
    Psychopharmacology, 2020, Volume: 237, Issue:9

    Topics: Alanine; Analgesics, Opioid; Animals; Glycine; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Oleic Acids; Rats; Rats, Sprague-Dawley; Reward; Substance Withdrawal Syndrome

2020
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000